-
1
-
-
0344021409
-
Prions and the Immune System: A Journey Through Gut, Spleen, and Nerves
-
DOI 10.1016/S0065-2776(03)81004-0
-
A. Aguzzi Prions and the immune system: a journey through gut, spleen, and nerves Adv Immunol 81 2003 123 171 (Pubitemid 38009043)
-
(2003)
Advances in Immunology
, vol.81
, pp. 123-171
-
-
Aguzzi, A.1
-
2
-
-
33748857338
-
Pathogenesis of prion diseases: Current status and future outlook
-
DOI 10.1038/nrmicro1492, PII NRMICRO1492
-
A. Aguzzi, and M. Heikenwalder Pathogenesis of prion diseases: current status and future outlook Nat Rev Microbiol 4 2006 765 775 (Pubitemid 44420127)
-
(2006)
Nature Reviews Microbiology
, vol.4
, Issue.10
, pp. 765-775
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
4
-
-
0141614845
-
No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders
-
DOI 10.1080/14660820310011737
-
A. Ahmad-Annuar, P. Shah, M. Hafezparast, H. Hummerich, A.S. Witherden, and K.E. Morrison No association with common Caucasian genotypes in exons 8, 13 and 14 of the human cytoplasmic dynein heavy chain gene (DNCHC1) and familial motor neuron disorders Amyotroph Lateral Scler Other Mot Neuron Disord 4 2003 150 157 (Pubitemid 37184883)
-
(2003)
Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders
, vol.4
, Issue.3
, pp. 150-157
-
-
Ahmad-Annuar, A.1
Sha, P.2
Hafezparast, M.3
Hummerich, H.4
Witherden, A.S.5
Morrison, K.E.6
Shaw, P.J.7
Kirby, J.8
Warner, T.T.9
Crosby, A.10
Proukakis, C.11
Wilkinson, P.12
Orell, R.W.13
Bradley, L.14
Martin, J.E.15
Fisher, E.M.C.16
-
5
-
-
0025613142
-
Basal ganglia-thalamocortical circuits: Parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions
-
G.E. Alexander, M.D. Crutcher, and M.R. DeLong Basal ganglia- thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions Prog Brain Res 85 1990 119 146
-
(1990)
Prog Brain Res
, vol.85
, pp. 119-146
-
-
Alexander, G.E.1
Crutcher, M.D.2
Delong, M.R.3
-
6
-
-
0028943648
-
Protein phosphatase 1 regulates the cytoplasmic dynein-driven formation of endoplasmic reticulum networks in vitro
-
V. Allan Protein phosphatase 1 regulates the cytoplasmic dynein-driven formation of endoplasmic reticulum networks in vitro J Cell Biol 128 1995 879 891
-
(1995)
J Cell Biol
, vol.128
, pp. 879-891
-
-
Allan, V.1
-
7
-
-
27744494043
-
Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival
-
DOI 10.1038/nature04256, PII N04256
-
E. Allen, J. Ding, W. Wang, S. Pramanik, J. Chou, and V. Yau Gigaxonin-controlled degradation of MAP1B light chain is critical to neuronal survival Nature 438 2005 224 228 (Pubitemid 41599874)
-
(2005)
Nature
, vol.438
, Issue.7065
, pp. 224-228
-
-
Allen, E.1
Ding, J.2
Wang, W.3
Pramanik, S.4
Chou, J.5
Yau, V.6
Yang, Y.7
-
8
-
-
33745498250
-
PLD1 and ERK2 regulate cytosolic lipid droplet formation
-
DOI 10.1242/jcs.02941
-
L. Andersson, P. Bostrom, J. Ericson, M. Rutberg, B. Magnusson, and D. Marchesan PLD1 and ERK2 regulate cytosolic lipid droplet formation J Cell Sci 119 2006 2246 2257 (Pubitemid 43960314)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.11
, pp. 2246-2257
-
-
Andersson, L.1
Bostrom, P.2
Ericson, J.3
Rutberg, M.4
Magnusson, B.5
Marchesan, D.6
Ruiz, M.7
Asp, L.8
Huang, P.9
Frohman, M.A.10
Boren, J.11
Olofsson, S.-O.12
-
9
-
-
0027176364
-
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
-
DOI 10.1038/ng0893-398
-
S.E. Andrew, Y.P. Goldberg, B. Kremer, H. Telenius, J. Theilmann, and S. Adam The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease Nat Genet 4 1993 398 403 (Pubitemid 23231490)
-
(1993)
Nature Genetics
, vol.4
, Issue.4
, pp. 398-403
-
-
Andrew, S.E.1
Goldberg, Y.P.2
Kremer, B.3
Telenius, H.4
Theilmann, J.5
Adam, S.6
Starr, E.7
Squitieri, F.8
Lin, B.9
Kalchman, M.A.10
Graham, R.K.11
Hayden, M.R.12
-
10
-
-
0027730175
-
Cytoplasmic dynein-dependent vesicular transport from early to late endosomes
-
DOI 10.1083/jcb.123.6.1373
-
F. Aniento, N. Emans, G. Griffiths, and J. Gruenberg Cytoplasmic dynein-dependent vesicular transport from early to late endosomes J Cell Biol 123 1993 1373 1387 (Pubitemid 24012018)
-
(1993)
Journal of Cell Biology
, vol.123
, Issue.6
, pp. 1373-1387
-
-
Aniento, F.1
Emans, N.2
Griffiths, G.3
Gruenberg, J.4
-
11
-
-
33846224191
-
Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations
-
DOI 10.1523/JNEUROSCI.4798-06.2007
-
R.H. Baloh, R.E. Schmidt, A. Pestronk, and J. Milbrandt Altered axonal mitochondrial transport in the pathogenesis of Charcot-Marie-Tooth disease from mitofusin 2 mutations J Neurosci 27 2007 422 430 (Pubitemid 46106016)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.2
, pp. 422-430
-
-
Baloh, R.H.1
Schmidt, R.E.2
Pestronk, A.3
Milbrandt, J.4
-
12
-
-
78149471570
-
Autophagy in neurodegenerative disorders: Pathogenic roles and therapeutic implications
-
R. Banerjee, M.F. Beal, and B. Thomas Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications Trends Neurosci 33 12 2010 541 549
-
(2010)
Trends Neurosci
, vol.33
, Issue.12
, pp. 541-549
-
-
Banerjee, R.1
Beal, M.F.2
Thomas, B.3
-
13
-
-
0033432837
-
Pathophysiology of chorea and bradykinesia in Huntington's disease
-
DOI 10.1002/1531-8257(199905)14:3<398::AID-MDS1003>3.0.CO;2-F
-
A. Berardelli, J. Noth, P.D. Thompson, E.L. Bollen, A. Curra, and G. Deuschl Pathophysiology of chorea and bradykinesia in Huntington's disease Mov Disord 14 1999 398 403 (Pubitemid 30011648)
-
(1999)
Movement Disorders
, vol.14
, Issue.3
, pp. 398-403
-
-
Berardelli, A.1
Noth, J.2
Thompson, P.D.3
Bollen, E.L.E.M.4
Curra, A.5
Deuschl, G.6
Van Dijk, J.G.7
Topper, R.8
Schwarz, M.9
Roos, R.A.C.10
-
14
-
-
33846199544
-
Dynactin enhances the processivity of kinesin-2
-
DOI 10.1111/j.1600-0854.2006.00517.x
-
M.A. Berezuk, and T.A. Schroer Dynactin enhances the processivity of kinesin-2 Traffic 8 2007 124 129 (Pubitemid 46099999)
-
(2007)
Traffic
, vol.8
, Issue.2
, pp. 124-129
-
-
Berezuk, M.A.1
Schroer, T.A.2
-
15
-
-
77953886784
-
Current status on Alzheimer disease molecular genetics: From past, to present, to future
-
K. Bettens, K. Sleegers, and C. Van Broeckhoven Current status on Alzheimer disease molecular genetics: from past, to present, to future Hum Mol Genet 19 2010 R4 R11
-
(2010)
Hum Mol Genet
, vol.19
-
-
Bettens, K.1
Sleegers, K.2
Van Broeckhoven, C.3
-
16
-
-
0023813668
-
Modifications of microtubule proteins in ALS nerve precede detectable histologic and ultrastructural changes
-
S. Binet, and V. Meininger Modifications of microtubule proteins in ALS nerve precede detectable histologic and ultrastructural changes Neurology 38 1988 1596 1600
-
(1988)
Neurology
, vol.38
, pp. 1596-1600
-
-
Binet, S.1
Meininger, V.2
-
17
-
-
33746310315
-
Alzheimer's disease
-
DOI 10.1016/S0140-6736(06)69113-7, PII S0140673606691137
-
K. Blennow, M.J. de Leon, and H. Zetterberg Alzheimer's disease Lancet 368 2006 387 403 (Pubitemid 44108123)
-
(2006)
Lancet
, vol.368
, Issue.9533
, pp. 387-403
-
-
Blennow, K.1
De Leon, M.J.2
Zetterberg, H.3
-
18
-
-
33749056809
-
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
-
DOI 10.1016/j.neuron.2006.09.018, PII S0896627306007252
-
S. Boillee, C. Vande Velde, and D.W. Cleveland ALS: a disease of motor neurons and their nonneuronal neighbors Neuron 52 2006 39 59 (Pubitemid 44466358)
-
(2006)
Neuron
, vol.52
, Issue.1
, pp. 39-59
-
-
Boillee, S.1
Vande Velde, C.2
Cleveland, DonW.3
-
19
-
-
0028356488
-
Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems
-
D.R. Borchelt, V.E. Koliatsos, M. Guarnieri, C.A. Pardo, S.S. Sisodia, and D.L. Price Rapid anterograde axonal transport of the cellular prion glycoprotein in the peripheral and central nervous systems J Biol Chem 269 1994 14711 14714 (Pubitemid 24194036)
-
(1994)
Journal of Biological Chemistry
, vol.269
, Issue.20
, pp. 14711-14714
-
-
Borchelt, D.R.1
Koliatsos, V.E.2
Guarnieri, M.3
Pardo, C.A.4
Sisodia, S.S.5
Price, D.L.6
-
20
-
-
35748972649
-
SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity
-
DOI 10.1038/ncb1648, PII NCB1648
-
P. Bostrom, L. Andersson, M. Rutberg, J. Perman, U. Lidberg, and B.R. Johansson SNARE proteins mediate fusion between cytosolic lipid droplets and are implicated in insulin sensitivity Nat Cell Biol 9 2007 1286 1293 (Pubitemid 350042360)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.11
, pp. 1286-1293
-
-
Bostrom, P.1
Andersson, L.2
Rutberg, M.3
Perman, J.4
Lidberg, U.5
Johansson, B.R.6
Fernandez-Rodriguez, J.7
Ericson, J.8
Nilsson, T.9
Boren, J.10
Olofsson, S.-O.11
-
21
-
-
24144438938
-
Cytosolic lipid droplets increase in size by microtubule-dependent complex formation
-
DOI 10.1161/01.ATV.0000179676.41064.d4
-
P. Bostrom, M. Rutberg, J. Ericsson, P. Holmdahl, L. Andersson, and M.A. Frohman Cytosolic lipid droplets increase in size by microtubule-dependent complex formation Arterioscler Thromb Vasc Biol 25 2005 1945 1951 (Pubitemid 41243467)
-
(2005)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.25
, Issue.9
, pp. 1945-1951
-
-
Bostrom, P.1
Rutberg, M.2
Ericsson, J.3
Holmdahl, P.4
Andersson, L.5
Frohman, M.A.6
Boren, J.7
Olofsson, S.-O.8
-
22
-
-
26844505808
-
Toxin-induced models of Parkinson's disease
-
DOI 10.1602/neurorx.2.3.484
-
J. Bove, D. Prou, C. Perier, and S. Przedborski Toxin-induced models of Parkinson's disease NeuroRx 2 2005 484 494 (Pubitemid 41444882)
-
(2005)
NeuroRx
, vol.2
, Issue.3
, pp. 484-494
-
-
Bove, J.1
Prou, D.2
Perier, C.3
Przedborski, S.4
-
23
-
-
77958479351
-
A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons
-
10.1093/hmg/ddq1361
-
K.E. Braunstein, J. Eschbach, K. Rona-Voros, R. Soylu, E. Mikrouli, and Y. Larmet A point mutation in the dynein heavy chain gene leads to striatal atrophy and compromises neurite outgrowth of striatal neurons Hum Mol Genet 2010 10.1093/hmg/ddq1361
-
(2010)
Hum Mol Genet
-
-
Braunstein, K.E.1
Eschbach, J.2
Rona-Voros, K.3
Soylu, R.4
Mikrouli, E.5
Larmet, Y.6
-
24
-
-
0023219957
-
Fast axonal transport in amyotrophic lateral sclerosis: An intra-axonal organelle traffic analysis
-
A.C. Breuer, M.P. Lynn, M.B. Atkinson, S.M. Chou, A.J. Wilbourn, and K.E. Marks Fast axonal transport in amyotrophic lateral sclerosis: an intra-axonal organelle traffic analysis Neurology 37 1987 738 748 (Pubitemid 17064659)
-
(1987)
Neurology
, vol.37
, Issue.5
, pp. 738-748
-
-
Breuer, A.C.1
Lynn, M.P.2
Atkinson, M.B.3
-
25
-
-
0002434444
-
Natural history of amyotrophic lateral sclerosis
-
B.R. Brooks, M. Sanjak, D. Belden, K. Juhasz-Poscine, and A. Waclawik Natural history of amyotrophic lateral sclerosis R.H.J. Brown, V. Meininger, M. Swash, Amyotrophic Lateral Sclerosis 2000 Dunitz London 31 58
-
(2000)
Amyotrophic Lateral Sclerosis
, pp. 31-58
-
-
Brooks, B.R.1
Sanjak, M.2
Belden, D.3
Juhasz-Poscine, K.4
Waclawik, A.5
-
26
-
-
0036849511
-
Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport
-
J. Brownlees, S. Ackerley, A.J. Grierson, N.J. Jacobsen, K. Shea, and B.H. Anderton Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport Hum Mol Genet 11 2002 2837 2844 (Pubitemid 35331816)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.23
, pp. 2837-2844
-
-
Brownlees, J.1
Ackerley, S.2
Grierson, A.J.3
Jacobsen, N.J.O.4
Shea, K.5
Anderton, B.H.6
Leigh, P.N.7
Shaw, C.E.8
Miller, C.C.J.9
-
27
-
-
0030727535
-
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution
-
DOI 10.1083/jcb.139.2.469
-
J.K. Burkhardt, C.J. Echeverri, T. Nilsson, and R.B. Vallee Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution J Cell Biol 139 1997 469 484 (Pubitemid 27459318)
-
(1997)
Journal of Cell Biology
, vol.139
, Issue.2
, pp. 469-484
-
-
Burkhardt, J.K.1
Echeverri, C.J.2
Nilsson, T.3
Vallee, R.B.4
-
29
-
-
13244295520
-
The highways and byways of prion protein trafficking
-
DOI 10.1016/j.tcb.2004.12.002, PII S0962892404003344
-
V. Campana, D. Sarnataro, and C. Zurzolo The highways and byways of prion protein trafficking Trends Cell Biol 15 2005 102 111 (Pubitemid 40188220)
-
(2005)
Trends in Cell Biology
, vol.15
, Issue.2
, pp. 102-111
-
-
Campana, V.1
Sarnataro, D.2
Zurzolo, C.3
-
30
-
-
4644319713
-
Aβ localization in abnormal endosomes: Association with earliest Aβ elevations in AD and Down syndrome
-
DOI 10.1016/j.neurobiolaging.2004.02.027, PII S0197458004001150
-
A.M. Cataldo, S. Petanceska, N.B. Terio, C.M. Peterhoff, R. Durham, and M. Mercken Abeta localization in abnormal endosomes: association with earliest Abeta elevations in AD and Down syndrome Neurobiol Aging 25 2004 1263 1272 (Pubitemid 39299162)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.10
, pp. 1263-1272
-
-
Cataldo, A.M.1
Petanceska, S.2
Terio, N.B.3
Peterhoff, C.M.4
Durham, R.5
Mercken, M.6
Mehta, P.D.7
Buxbaum, J.8
Haroutunian, V.9
Nixon, R.A.10
-
31
-
-
0033869715
-
Endocytic pathway abnormalities precede amyloid β deposition in sporadic alzheimer's disease and down syndrome: Differential effects of APOE genotype and presenilin mutations
-
A.M. Cataldo, C.M. Peterhoff, J.C. Troncoso, T. Gomez-Isla, B.T. Hyman, and R.A. Nixon Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer's disease and Down syndrome: differential effects of APOE genotype and presenilin mutations Am J Pathol 157 2000 277 286 (Pubitemid 30641743)
-
(2000)
American Journal of Pathology
, vol.157
, Issue.1
, pp. 277-286
-
-
Cataldo, A.M.1
Peterhoff, C.M.2
Troncoso, J.C.3
Gomez-Isla, T.4
Hyman, B.T.5
Nixon, R.A.6
-
32
-
-
34547193908
-
Huntingtin facilitates dynein/dynactin-mediated vesicle transport
-
DOI 10.1073/pnas.0610628104
-
J.P. Caviston, J.L. Ross, S.M. Antony, M. Tokito, and E.L. Holzbaur Huntingtin facilitates dynein/dynactin-mediated vesicle transport Proc Natl Acad Sci U S A 104 2007 10045 10050 (Pubitemid 47175260)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10045-10050
-
-
Caviston, J.P.1
Ross, J.L.2
Antony, S.M.3
Tokito, M.4
Holzbaur, E.L.F.5
-
33
-
-
78650048929
-
Characterisation of the properties of a novel mutation in VAPB in familial ALS
-
H.J. Chen, G. Anagnostou, A. Chai, J. Withers, A. Morris, and J. Adhikaree Characterisation of the properties of a novel mutation in VAPB in familial ALS J Biol Chem 285 51 2010 40266 40281
-
(2010)
J Biol Chem
, vol.285
, Issue.51
, pp. 40266-40281
-
-
Chen, H.J.1
Anagnostou, G.2
Chai, A.3
Withers, J.4
Morris, A.5
Adhikaree, J.6
-
34
-
-
37549068958
-
Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene
-
X.J. Chen, E.N. Levedakou, K.J. Millen, R.L. Wollmann, B. Soliven, and B. Popko Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene J Neurosci 27 2007 14515 14524
-
(2007)
J Neurosci
, vol.27
, pp. 14515-14524
-
-
Chen, X.J.1
Levedakou, E.N.2
Millen, K.J.3
Wollmann, R.L.4
Soliven, B.5
Popko, B.6
-
36
-
-
45749094601
-
Glued subunit of dynactin
-
DOI 10.1093/hmg/ddn092
-
E.S. Chevalier-Larsen, K.E. Wallace, C.R. Pennise, and E.L. Holzbaur Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin Hum Mol Genet 17 2008 1946 1955 (Pubitemid 351865843)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.13
, pp. 1946-1955
-
-
Chevalier-Larsen, E.S.1
Wallace, K.E.2
Pennise, C.R.3
Holzbaur, E.L.F.4
-
37
-
-
58049192812
-
Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS
-
C.Y. Chow, J.E. Landers, S.K. Bergren, P.C. Sapp, A.E. Grant, and J.M. Jones Deleterious variants of FIG4, a phosphoinositide phosphatase, in patients with ALS Am J Hum Genet 84 2009 85 88
-
(2009)
Am J Hum Genet
, vol.84
, pp. 85-88
-
-
Chow, C.Y.1
Landers, J.E.2
Bergren, S.K.3
Sapp, P.C.4
Grant, A.E.5
Jones, J.M.6
-
38
-
-
77956123201
-
Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi
-
Y.L. Clarkson, T. Gillespie, E.M. Perkins, A.R. Lyndon, and M. Jackson Beta-III spectrin mutation L253P associated with spinocerebellar ataxia type 5 interferes with binding to Arp1 and protein trafficking from the Golgi Hum Mol Genet 19 2010 3634 3641
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3634-3641
-
-
Clarkson, Y.L.1
Gillespie, T.2
Perkins, E.M.3
Lyndon, A.R.4
Jackson, M.5
-
39
-
-
18444379677
-
Akt is altered in an animal model of Huntington's disease and in patients
-
DOI 10.1111/j.1460-9568.2005.03985.x
-
E. Colin, E. Regulier, V. Perrin, A. Durr, A. Brice, and P. Aebischer Akt is altered in an animal model of Huntington's disease and in patients Eur J Neurosci 21 2005 1478 1488 (Pubitemid 40646594)
-
(2005)
European Journal of Neuroscience
, vol.21
, Issue.6
, pp. 1478-1488
-
-
Colin, E.1
Regulier, E.2
Perrin, V.3
Durr, A.4
Brice, A.5
Aebischer, P.6
Deglon, N.7
Humbert, S.8
Saudou, F.9
-
40
-
-
49149112606
-
Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
-
E. Colin, D. Zala, G. Liot, H. Rangone, M. Borrell-Pages, and X.J. Li Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons EMBO J 27 2008 2124 2134
-
(2008)
EMBO J
, vol.27
, pp. 2124-2134
-
-
Colin, E.1
Zala, D.2
Liot, G.3
Rangone, H.4
Borrell-Pages, M.5
Li, X.J.6
-
41
-
-
33746533924
-
α-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
DOI 10.1126/science.1129462
-
A.A. Cooper, A.D. Gitler, A. Cashikar, C.M. Haynes, K.J. Hill, and B. Bhullar Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models Science 313 2006 324 328 (Pubitemid 44480951)
-
(2006)
Science
, vol.313
, Issue.5785
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
Bhullar, B.6
Liu, K.7
Xu, K.8
Strathearn, K.E.9
Liu, F.10
Cao, S.11
Caldwell, K.A.12
Caldwell, G.A.13
Marsischky, G.14
Kolodner, R.D.15
LaBaer, J.16
Rochet, J.-C.17
Bonini, N.M.18
Lindquist, S.19
-
42
-
-
0026760941
-
Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex
-
I. Corthesy-Theulaz, A. Pauloin, and S.R. Pfeffer Cytoplasmic dynein participates in the centrosomal localization of the Golgi complex J Cell Biol 118 1992 1333 1345
-
(1992)
J Cell Biol
, vol.118
, pp. 1333-1345
-
-
Corthesy-Theulaz, I.1
Pauloin, A.2
Pfeffer, S.R.3
-
43
-
-
53949113331
-
Action in the axon: Generation and transport of signaling endosomes
-
K.E. Cosker, S.L. Courchesne, and R.A. Segal Action in the axon: generation and transport of signaling endosomes Curr Opin Neurobiol 18 2008 270 275
-
(2008)
Curr Opin Neurobiol
, vol.18
, pp. 270-275
-
-
Cosker, K.E.1
Courchesne, S.L.2
Segal, R.A.3
-
44
-
-
77956392186
-
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS)
-
L.E. Cox, L. Ferraiuolo, E.F. Goodall, P.R. Heath, A. Higginbottom, and H. Mortiboys Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS) PLoS ONE 5 2010 e9872
-
(2010)
PLoS ONE
, vol.5
, pp. 9872
-
-
Cox, L.E.1
Ferraiuolo, L.2
Goodall, E.F.3
Heath, P.R.4
Higginbottom, A.5
Mortiboys, H.6
-
45
-
-
59349089711
-
Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin
-
C. Creppe, L. Malinouskaya, M.L. Volvert, M. Gillard, P. Close, and O. Malaise Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin Cell 136 2009 551 564
-
(2009)
Cell
, vol.136
, pp. 551-564
-
-
Creppe, C.1
Malinouskaya, L.2
Volvert, M.L.3
Gillard, M.4
Close, P.5
Malaise, O.6
-
46
-
-
77953892400
-
Molecular mechanisms of neurodegeneration in Alzheimer's disease
-
L. Crews, and E. Masliah Molecular mechanisms of neurodegeneration in Alzheimer's disease Hum Mol Genet 19 2010 R12 R20
-
(2010)
Hum Mol Genet
, vol.19
-
-
Crews, L.1
Masliah, E.2
-
47
-
-
77953463398
-
Protein degradation, aggregation, and misfolding
-
A.M. Cuervo, E.S. Wong, and M. Martinez-Vicente Protein degradation, aggregation, and misfolding Mov Disord 25 Suppl. 1 2010 S49 S54
-
(2010)
Mov Disord
, vol.25
, Issue.SUPPL. 1
-
-
Cuervo, A.M.1
Wong, E.S.2
Martinez-Vicente, M.3
-
48
-
-
33749042331
-
Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
-
DOI 10.1016/j.cell.2006.09.015, PII S0092867406012050
-
L. Cui, H. Jeong, F. Borovecki, C.N. Parkhurst, N. Tanese, and D. Krainc Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration Cell 127 2006 59 69 (Pubitemid 44466642)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
49
-
-
65549140785
-
DYNC2H1 mutations cause asphyxiating thoracic dystrophy and short rib-polydactyly syndrome, type III
-
N. Dagoneau, M. Goulet, D. Genevieve, Y. Sznajer, J. Martinovic, and S. Smithson DYNC2H1 mutations cause asphyxiating thoracic dystrophy and short rib-polydactyly syndrome, type III Am J Hum Genet 84 2009 706 711
-
(2009)
Am J Hum Genet
, vol.84
, pp. 706-711
-
-
Dagoneau, N.1
Goulet, M.2
Genevieve, D.3
Sznajer, Y.4
Martinovic, J.5
Smithson, S.6
-
50
-
-
44649154996
-
Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B
-
A. De Luca, C. Progida, M.R. Spinosa, P. Alifano, and C. Bucci Characterization of the Rab7K157N mutant protein associated with Charcot-Marie-Tooth type 2B Biochem Biophys Res Commun 372 2008 283 287
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 283-287
-
-
De Luca, A.1
Progida, C.2
Spinosa, M.R.3
Alifano, P.4
Bucci, C.5
-
51
-
-
35548991459
-
Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content
-
DOI 10.1093/hmg/ddm226
-
K.J. De Vos, A.L. Chapman, M.E. Tennant, C. Manser, E.L. Tudor, and K.F. Lau Familial amyotrophic lateral sclerosis-linked SOD1 mutants perturb fast axonal transport to reduce axonal mitochondria content Hum Mol Genet 16 2007 2720 2728 (Pubitemid 350018514)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.22
, pp. 2720-2728
-
-
De Vos, K.J.1
Chapman, A.L.2
Tennant, M.E.3
Manser, C.4
Tudor, E.L.5
Lau, K.-F.6
Brownlees, J.7
Ackerley, S.8
Shaw, P.J.9
Mcloughlin, D.M.10
Shaw, C.E.11
Leigh, P.N.12
Miller, C.C.J.13
Grierson, A.J.14
-
53
-
-
77954466407
-
Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons
-
H. Decker, K.Y. Lo, S.M. Unger, S.T. Ferreira, and M.A. Silverman Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons J Neurosci 30 2010 9166 9171
-
(2010)
J Neurosci
, vol.30
, pp. 9166-9171
-
-
Decker, H.1
Lo, K.Y.2
Unger, S.M.3
Ferreira, S.T.4
Silverman, M.A.5
-
54
-
-
33749620373
-
Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway
-
DOI 10.1016/j.neuron.2006.08.018, PII S0896627306006404
-
K. Deinhardt, S. Salinas, C. Verastegui, R. Watson, D. Worth, and S. Hanrahan Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway Neuron 52 2006 293 305 (Pubitemid 44548343)
-
(2006)
Neuron
, vol.52
, Issue.2
, pp. 293-305
-
-
Deinhardt, K.1
Salinas, S.2
Verastegui, C.3
Watson, R.4
Worth, D.5
Hanrahan, S.6
Bucci, C.7
Schiavo, G.8
-
55
-
-
0037899137
-
NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
-
DOI 10.1016/S0896-6273(03)00397-0
-
J.D. Delcroix, J.S. Valletta, C. Wu, S.J. Hunt, A.S. Kowal, and W.C. Mobley NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals Neuron 39 2003 69 84 (Pubitemid 36830949)
-
(2003)
Neuron
, vol.39
, Issue.1
, pp. 69-84
-
-
Delcroix, J.-D.1
Valletta, J.S.2
Wu, C.3
Hunt, S.J.4
Kowal, A.S.5
Mobley, W.C.6
-
56
-
-
77952932485
-
FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis
-
H.X. Deng, H. Zhai, E.H. Bigio, J. Yan, F. Fecto, and K. Ajroud FUS-immunoreactive inclusions are a common feature in sporadic and non-SOD1 familial amyotrophic lateral sclerosis Ann Neurol 67 2010 739 748
-
(2010)
Ann Neurol
, vol.67
, pp. 739-748
-
-
Deng, H.X.1
Zhai, H.2
Bigio, E.H.3
Yan, J.4
Fecto, F.5
Ajroud, K.6
-
57
-
-
77954162482
-
Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E
-
F. Dequen, M. Filali, R.C. Lariviere, R. Perrot, S. Hisanaga, and J.P. Julien Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E Hum Mol Genet 19 2010 2616 2629
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2616-2629
-
-
Dequen, F.1
Filali, M.2
Lariviere, R.C.3
Perrot, R.4
Hisanaga, S.5
Julien, J.P.6
-
58
-
-
33745473350
-
Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities
-
DOI 10.1073/pnas.0510197103
-
R.S. Devon, P.C. Orban, K. Gerrow, M.A. Barbieri, C. Schwab, and L.P. Cao Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities Proc Natl Acad Sci U S A 103 2006 9595 9600 (Pubitemid 43955870)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.25
, pp. 9595-9600
-
-
Devon, R.S.1
Orban, P.C.2
Gerrow, K.3
Barbieri, M.A.4
Schwab, C.5
Cao, L.P.6
Helm, J.R.7
Bissada, M.8
Cruz-Aguado, R.9
Davidson, T.-L.10
Witmer, J.11
Metzler, M.12
Lam, C.K.13
Tetzlaff, W.14
Simpson, E.M.15
McCaffery, J.M.16
El-Husseini, A.E.17
Leavitt, B.R.18
Hayden, M.R.19
-
59
-
-
70350161427
-
Bicaudal-D and its role in cargo sorting by microtubule-based motors
-
M. Dienstbier, and X. Li Bicaudal-D and its role in cargo sorting by microtubule-based motors Biochem Soc Trans 37 2009 1066 1071
-
(2009)
Biochem Soc Trans
, vol.37
, pp. 1066-1071
-
-
Dienstbier, M.1
Li, X.2
-
60
-
-
0028989602
-
Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons
-
M. DiFiglia, E. Sapp, K. Chase, C. Schwarz, A. Meloni, and C. Young Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons Neuron 14 1995 1075 1081
-
(1995)
Neuron
, vol.14
, pp. 1075-1081
-
-
Difiglia, M.1
Sapp, E.2
Chase, K.3
Schwarz, C.4
Meloni, A.5
Young, C.6
-
61
-
-
33646140347
-
Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport
-
J. Ding, E. Allen, W. Wang, A. Valle, C. Wu, and T. Nardine Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport Hum Mol Genet 15 2006 1451 1463
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1451-1463
-
-
Ding, J.1
Allen, E.2
Wang, W.3
Valle, A.4
Wu, C.5
Nardine, T.6
-
62
-
-
39749165656
-
Differential regulation of dynein and kinesin motor proteins by tau
-
DOI 10.1126/science.1152993
-
R. Dixit, J.L. Ross, Y.E. Goldman, and E.L. Holzbaur Differential regulation of dynein and kinesin motor proteins by tau Science 319 2008 1086 1089 (Pubitemid 351300789)
-
(2008)
Science
, vol.319
, Issue.5866
, pp. 1086-1089
-
-
Dixit, R.1
Ross, J.L.2
Goldman, Y.E.3
Holzbaur, E.L.F.4
-
63
-
-
34047175919
-
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation
-
DOI 10.1523/JNEUROSCI.0037-07.2007
-
J.P. Dompierre, J.D. Godin, B.C. Charrin, F.P. Cordelieres, S.J. King, and S. Humbert Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation J Neurosci 27 2007 3571 3583 (Pubitemid 46515140)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.13
, pp. 3571-3583
-
-
Dompierre, J.P.1
Godin, J.D.2
Charrin, B.C.3
Cordelieres, F.P.4
King, S.J.5
Humbert, S.6
Saudou, F.7
-
64
-
-
33845905221
-
Dynein is required for receptor sorting and the morphogenesis of early endosomes
-
DOI 10.1038/ncb1525, PII NCB1525
-
O.J. Driskell, A. Mironov, V.J. Allan, and P.G. Woodman Dynein is required for receptor sorting and the morphogenesis of early endosomes Nat Cell Biol 9 2007 113 120 (Pubitemid 46024205)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.1
, pp. 113-120
-
-
Driskell, O.J.1
Mironov, A.2
Allan, V.J.3
Woodman, P.G.4
-
65
-
-
77957973735
-
Skeletal muscle in motor neuron diseases: Therapeutic target and delivery route for potential treatments
-
L. Dupuis, and A. Echaniz-Laguna Skeletal muscle in motor neuron diseases: therapeutic target and delivery route for potential treatments Curr Drug Targets 11 10 2010 1250 1261
-
(2010)
Curr Drug Targets
, vol.11
, Issue.10
, pp. 1250-1261
-
-
Dupuis, L.1
Echaniz-Laguna, A.2
-
66
-
-
57649107154
-
Mice with a mutation in the dynein heavy chain 1 gene display sensory neuropathy but lack motor neuron disease
-
L. Dupuis, A. Fergani, K.E. Braunstein, J. Eschbach, N. Holl, and F. Rene Mice with a mutation in the dynein heavy chain 1 gene display sensory neuropathy but lack motor neuron disease Exp Neurol 215 2009 146 152
-
(2009)
Exp Neurol
, vol.215
, pp. 146-152
-
-
Dupuis, L.1
Fergani, A.2
Braunstein, K.E.3
Eschbach, J.4
Holl, N.5
Rene, F.6
-
67
-
-
65949094823
-
Neuromuscular junction destruction during amyotrophic lateral sclerosis: Insights from transgenic models
-
L. Dupuis, and J.P. Loeffler Neuromuscular junction destruction during amyotrophic lateral sclerosis: insights from transgenic models Curr Opin Pharmacol 9 2009 341 346
-
(2009)
Curr Opin Pharmacol
, vol.9
, pp. 341-346
-
-
Dupuis, L.1
Loeffler, J.P.2
-
68
-
-
77955636420
-
Autosomal dominant cerebellar ataxias: Polyglutamine expansions and beyond
-
A. Durr Autosomal dominant cerebellar ataxias: polyglutamine expansions and beyond Lancet Neurol 9 2010 885 894
-
(2010)
Lancet Neurol
, vol.9
, pp. 885-894
-
-
Durr, A.1
-
69
-
-
77953309202
-
The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease
-
A.M. El-Kadi, V. Bros-Facer, W. Deng, A. Philpott, E. Stoddart, and G. Banks The legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease J Biol Chem 285 2010 18627 18639
-
(2010)
J Biol Chem
, vol.285
, pp. 18627-18639
-
-
El-Kadi, A.M.1
Bros-Facer, V.2
Deng, W.3
Philpott, A.4
Stoddart, E.5
Banks, G.6
-
70
-
-
0030726894
-
Huntingtin-associated protein 1 (HAP1) interacts with the p150(Glued) subunit of dynactin
-
S. Engelender, A.H. Sharp, V. Colomer, M.K. Tokito, A. Lanahan, and P. Worley Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin Hum Mol Genet 6 1997 2205 2212 (Pubitemid 27501070)
-
(1997)
Human Molecular Genetics
, vol.6
, Issue.13
, pp. 2205-2212
-
-
Engelender, S.1
Sharp, A.H.2
Colomer, V.3
Tokito, M.K.4
Lanahan, A.5
Worley, P.6
Holzbaur, E.L.F.7
Ross, C.A.8
-
71
-
-
70049087124
-
Impaired axonal transport in motor neurons correlates with clinical prion disease
-
V. Ermolayev, T. Cathomen, J. Merk, M. Friedrich, W. Hartig, and G.S. Harms Impaired axonal transport in motor neurons correlates with clinical prion disease PLoS Pathog 5 2009 e1000558
-
(2009)
PLoS Pathog
, vol.5
, pp. 1000558
-
-
Ermolayev, V.1
Cathomen, T.2
Merk, J.3
Friedrich, M.4
Hartig, W.5
Harms, G.S.6
-
72
-
-
67649400910
-
Ultramicroscopy reveals axonal transport impairments in cortical motor neurons at prion disease
-
V. Ermolayev, M. Friedrich, R. Nozadze, T. Cathomen, M.A. Klein, and G.S. Harms Ultramicroscopy reveals axonal transport impairments in cortical motor neurons at prion disease Biophys J 96 2009 3390 3398
-
(2009)
Biophys J
, vol.96
, pp. 3390-3398
-
-
Ermolayev, V.1
Friedrich, M.2
Nozadze, R.3
Cathomen, T.4
Klein, M.A.5
Harms, G.S.6
-
73
-
-
78650299647
-
Mutations in cytoplasmic dynein lead to a Huntington's disease-like defect in energy metabolism of brown and white adipose tissues
-
J. Eschbach, A. Fergani, H. Oudart, J.P. Robin, F. Rene, and J.L. de Aguilar Mutations in cytoplasmic dynein lead to a Huntington's disease-like defect in energy metabolism of brown and white adipose tissues Biochim Biophys Acta 1812 1 2011 59 69
-
(2011)
Biochim Biophys Acta
, vol.1812
, Issue.1
, pp. 59-69
-
-
Eschbach, J.1
Fergani, A.2
Oudart, H.3
Robin, J.P.4
Rene, F.5
De Aguilar, J.L.6
-
74
-
-
0036724052
-
Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene
-
DOI 10.1086/342359
-
E. Eymard-Pierre, G. Lesca, S. Dollet, F.M. Santorelli, M. di Capua, and E. Bertini Infantile-onset ascending hereditary spastic paralysis is associated with mutations in the alsin gene Am J Hum Genet 71 2002 518 527 (Pubitemid 34970123)
-
(2002)
American Journal of Human Genetics
, vol.71
, Issue.3
, pp. 518-527
-
-
Eymard-Pierre, E.1
Lesca, G.2
Dollet, S.3
Santorelli, F.M.4
Di Capua, M.5
Bertini, E.6
Boespflug-Tanguy, O.7
-
75
-
-
59149097039
-
DCTN1 mutations in Perry syndrome
-
M.J. Farrer, M.M. Hulihan, J.M. Kachergus, J.C. Dachsel, A.J. Stoessl, and L.L. Grantier DCTN1 mutations in Perry syndrome Nat Genet 41 2009 163 165
-
(2009)
Nat Genet
, vol.41
, pp. 163-165
-
-
Farrer, M.J.1
Hulihan, M.M.2
Kachergus, J.M.3
Dachsel, J.C.4
Stoessl, A.J.5
Grantier, L.L.6
-
76
-
-
35948983328
-
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
-
DOI 10.1083/jcb.200702115
-
M. Filimonenko, S. Stuffers, C. Raiborg, A. Yamamoto, L. Malerod, and E.M. Fisher Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease J Cell Biol 179 2007 485 500 (Pubitemid 350074792)
-
(2007)
Journal of Cell Biology
, vol.179
, Issue.3
, pp. 485-500
-
-
Filimonenko, M.1
Stuffers, S.2
Raiborg, C.3
Yamamoto, A.4
Malerod, L.5
Fisher, E.M.C.6
Isaacs, A.7
Brech, A.8
Stenmark, H.9
Simonsen, A.10
-
77
-
-
35948978460
-
Moving mitochondria: Establishing distribution of an essential organelle
-
DOI 10.1111/j.1600-0854.2007.00644.x
-
R.L. Frederick, and J.M. Shaw Moving mitochondria: establishing distribution of an essential organelle Traffic 8 2007 1668 1675 (Pubitemid 350066679)
-
(2007)
Traffic
, vol.8
, Issue.12
, pp. 1668-1675
-
-
Frederick, R.L.1
Shaw, J.M.2
-
78
-
-
37849000527
-
Evaluation tools and animal models of peripheral neuropathies
-
B. Fricker, A. Muller, and F. Rene Evaluation tools and animal models of peripheral neuropathies Neurodegener Dis 5 2008 72 108
-
(2008)
Neurodegener Dis
, vol.5
, pp. 72-108
-
-
Fricker, B.1
Muller, A.2
Rene, F.3
-
79
-
-
74749103945
-
UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration
-
H.N. Fridolfsson, N. Ly, M. Meyerzon, and D.A. Starr UNC-83 coordinates kinesin-1 and dynein activities at the nuclear envelope during nuclear migration Dev Biol 338 2010 237 250
-
(2010)
Dev Biol
, vol.338
, pp. 237-250
-
-
Fridolfsson, H.N.1
Ly, N.2
Meyerzon, M.3
Starr, D.A.4
-
80
-
-
33747811791
-
Fragmentation of Golgi apparatus of nigral neurons with α-synuclein-positive inclusions in patients with Parkinson's disease
-
DOI 10.1007/s00401-006-0114-4
-
Y. Fujita, E. Ohama, M. Takatama, S. Al-Sarraj, and K. Okamoto Fragmentation of Golgi apparatus of nigral neurons with alpha-synuclein-positive inclusions in patients with Parkinson's disease Acta Neuropathol 112 2006 261 265 (Pubitemid 44275881)
-
(2006)
Acta Neuropathologica
, vol.112
, Issue.3
, pp. 261-265
-
-
Fujita, Y.1
Ohama, E.2
Takatama, M.3
Al-Sarraj, S.4
Okamoto, K.5
-
81
-
-
77950170203
-
The p.P56S mutation in the VAPB gene is not due to a single founder: The first European case
-
A.D. Funke, M. Esser, A. Kruttgen, J. Weis, M. Mitne-Neto, and M. Lazar The p.P56S mutation in the VAPB gene is not due to a single founder: the first European case Clin Genet 77 2010 302 303
-
(2010)
Clin Genet
, vol.77
, pp. 302-303
-
-
Funke, A.D.1
Esser, M.2
Kruttgen, A.3
Weis, J.4
Mitne-Neto, M.5
Lazar, M.6
-
82
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
DOI 10.1016/j.cell.2004.06.018, PII S0092867404006191
-
L.R. Gauthier, B.C. Charrin, M. Borrell-Pages, J.P. Dompierre, H. Rangone, and F.P. Cordelieres Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules Cell 118 2004 127 138 (Pubitemid 38902819)
-
(2004)
Cell
, vol.118
, Issue.1
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
De Mey, J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
Saudou, F.11
-
83
-
-
0031444202
-
An extended microtubule-binding structure within the dynein motor domain
-
DOI 10.1038/37663
-
M.A. Gee, J.E. Heuser, and R.B. Vallee An extended microtubule-binding structure within the dynein motor domain Nature 390 1997 636 639 (Pubitemid 28016202)
-
(1997)
Nature
, vol.390
, Issue.6660
, pp. 636-639
-
-
Gee, M.A.1
Heuser, J.E.2
Vallee, R.B.3
-
84
-
-
38349160161
-
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis
-
A.D. Gitler, B.J. Bevis, J. Shorter, K.E. Strathearn, S. Hamamichi, and L.J. Su The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis Proc Natl Acad Sci U S A 105 2008 145 150
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 145-150
-
-
Gitler, A.D.1
Bevis, B.J.2
Shorter, J.3
Strathearn, K.E.4
Hamamichi, S.5
Su, L.J.6
-
85
-
-
77955436243
-
Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis
-
J.D. Godin, K. Colombo, M. Molina-Calavita, G. Keryer, D. Zala, and B.C. Charrin Huntingtin is required for mitotic spindle orientation and mammalian neurogenesis Neuron 67 2010 392 406
-
(2010)
Neuron
, vol.67
, pp. 392-406
-
-
Godin, J.D.1
Colombo, K.2
Molina-Calavita, M.3
Keryer, G.4
Zala, D.5
Charrin, B.C.6
-
86
-
-
33744531110
-
Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death
-
DOI 10.1016/j.jns.2006.01.019, PII S0022510X06000384
-
N.K. Gonatas, A. Stieber, and J.O. Gonatas Fragmentation of the Golgi apparatus in neurodegenerative diseases and cell death J Neurol Sci 246 2006 21 30 (Pubitemid 43815336)
-
(2006)
Journal of the Neurological Sciences
, vol.246
, Issue.1-2
, pp. 21-30
-
-
Gonatas, N.K.1
Stieber, A.2
Gonatas, J.O.3
-
87
-
-
34248149517
-
Amyotrophic lateral sclerosis: All roads lead to Rome
-
DOI 10.1111/j.1471-4159.2006.04408.x
-
J.L. Gonzalez de Aguilar, A. Echaniz-Laguna, A. Fergani, F. Rene, V. Meininger, and J.P. Loeffler Amyotrophic lateral sclerosis: all roads lead to Rome J Neurochem 101 5 2007 1153 1160 (Pubitemid 46718806)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.5
, pp. 1153-1160
-
-
Aguilar, J.-L.G.D.1
Echaniz-Laguna, A.2
Fergani, A.3
Rene, F.4
Meininger, V.5
Loeffler, J.-P.6
Dupuis, L.7
-
88
-
-
0037073748
-
Golgi fragmentation occurs in the cells with prefibrillar α-synuclein aggregates and precedes the formation of fibrillar inclusion
-
DOI 10.1074/jbc.M208194200
-
N. Gosavi, H.J. Lee, J.S. Lee, S. Patel, and S.J. Lee Golgi fragmentation occurs in the cells with prefibrillar alpha-synuclein aggregates and precedes the formation of fibrillar inclusion J Biol Chem 277 2002 48984 48992 (Pubitemid 35470870)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.50
, pp. 48984-48992
-
-
Gosavi, N.1
Lee, H.-J.2
Lee, J.S.3
Patel, S.4
Lee, S.-J.5
-
89
-
-
0042733013
-
Rab5-stimulated up-regulation of the endocytic pathway increases intracellular β-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Aβ production
-
DOI 10.1074/jbc.M304122200
-
O.M. Grbovic, P.M. Mathews, Y. Jiang, S.D. Schmidt, R. Dinakar, and N.B. Summers-Terio Rab5-stimulated up-regulation of the endocytic pathway increases intracellular beta-cleaved amyloid precursor protein carboxyl-terminal fragment levels and Abeta production J Biol Chem 278 2003 31261 31268 (Pubitemid 36994643)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.33
, pp. 31261-31268
-
-
Grbovic, O.M.1
Mathews, P.M.2
Jiang, Y.3
Schmidt, S.D.4
Dinakar, R.5
Summers-Terio, N.B.6
Ceresa, B.P.7
Nixon, R.A.8
Cataldo, A.M.9
-
90
-
-
33645422711
-
ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis
-
M.J. Greenway, P.M. Andersen, C. Russ, S. Ennis, S. Cashman, and C. Donaghy ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis Nat Genet 38 2006 411 413
-
(2006)
Nat Genet
, vol.38
, pp. 411-413
-
-
Greenway, M.J.1
Andersen, P.M.2
Russ, C.3
Ennis, S.4
Cashman, S.5
Donaghy, C.6
-
91
-
-
0034611001
-
Dynein-mediated cargo transport in vivo. A switch controls travel distance
-
S.P. Gross, M.A. Welte, S.M. Block, and E.F. Wieschaus Dynein-mediated cargo transport in vivo. A switch controls travel distance J Cell Biol 148 2000 945 956
-
(2000)
J Cell Biol
, vol.148
, pp. 945-956
-
-
Gross, S.P.1
Welte, M.A.2
Block, S.M.3
Wieschaus, E.F.4
-
92
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
DOI 10.1016/S0896-6273(03)00594-4
-
S. Gunawardena, L.S. Her, R.G. Brusch, R.A. Laymon, I.R. Niesman, and B. Gordesky-Gold Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila Neuron 40 2003 25 40 (Pubitemid 37222462)
-
(2003)
Neuron
, vol.40
, Issue.1
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.-S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.B.9
-
93
-
-
58349085737
-
What causes cell death in Parkinson's disease?
-
A. Gupta, V.L. Dawson, and T.M. Dawson What causes cell death in Parkinson's disease? Ann Neurol 64 Suppl. 2 2008 S3 S15
-
(2008)
Ann Neurol
, vol.64
, Issue.SUPPL. 2
-
-
Gupta, A.1
Dawson, V.L.2
Dawson, T.M.3
-
94
-
-
31144448704
-
Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking
-
DOI 10.1093/hmg/ddi440
-
S. Hadano, S.C. Benn, S. Kakuta, A. Otomo, K. Sudo, and R. Kunita Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking Hum Mol Genet 15 2006 233 250 (Pubitemid 43125978)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.2
, pp. 233-250
-
-
Hadano, S.1
Benn, S.C.2
Kakuta, S.3
Otomo, A.4
Sudo, K.5
Kunita, R.6
Suzuki-Utsunomiya, K.7
Mizumura, H.8
Shefner, J.M.9
Cox, G.A.10
Iwakura, Y.11
Brown Jr., R.H.12
Ikeda, J.-E.13
-
95
-
-
0034785483
-
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
-
DOI 10.1038/ng1001-166
-
S. Hadano, C.K. Hand, H. Osuga, Y. Yanagisawa, A. Otomo, and R.S. Devon A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2 Nat Genet 29 2001 166 173 (Pubitemid 32952653)
-
(2001)
Nature Genetics
, vol.29
, Issue.2
, pp. 166-173
-
-
Hadano, S.1
Hand, C.K.2
Osuga, H.3
Yanagisawa, Y.4
Otomo, A.5
Devon, R.S.6
Miyamoto, N.7
Showguchi-Miyata, J.8
Okada, Y.9
Singaraja, R.10
Figlewicz, D.A.11
Kwiatkowski, T.12
Hosler, B.A.13
Sagie, T.14
Skaug, J.15
Nasir, J.16
Brown, R.H.17
Scherer, S.W.18
Rouleau, G.A.19
Hayden, M.R.20
Ikeda, J.-E.21
more..
-
96
-
-
9644275349
-
Prion disease incubation time is not affected in mice heterozygous for a dynein mutation
-
DOI 10.1016/j.bbrc.2004.10.206, PII S0006291X0402532X
-
M. Hafezparast, S. Brandner, J. Linehan, J.E. Martin, J. Collinge, and E.M. Fisher Prion disease incubation time is not affected in mice heterozygous for a dynein mutation Biochem Biophys Res Commun 326 2005 18 22 (Pubitemid 39573194)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.326
, Issue.1
, pp. 18-22
-
-
Hafezparast, M.1
Brandner, S.2
Linehan, J.3
Martin, J.E.4
Collinge, J.5
Fisher, E.M.C.6
-
97
-
-
0037734370
-
Mutations in dynein link motor neuron degeneration to defects in retrograde transport
-
DOI 10.1126/science.1083129
-
M. Hafezparast, R. Klocke, C. Ruhrberg, A. Marquardt, A. Ahmad-Annuar, and S. Bowen Mutations in dynein link motor neuron degeneration to defects in retrograde transport Science 300 2003 808 812 (Pubitemid 36532118)
-
(2003)
Science
, vol.300
, Issue.5620
, pp. 808-812
-
-
Hafezparast, M.1
Klocke, R.2
Ruhrberg, C.3
Marquardt, A.4
Ahmad-Annuar, A.5
Bowen, S.6
Lalli, G.7
Witherden, A.S.8
Hummerich, H.9
Nicholson, S.10
Morgan, P.J.11
Oozageer, R.12
Priestley, J.V.13
Averill, S.14
King, V.R.15
Ball, S.16
Peters, J.17
Toda, T.18
Yamamoto, A.19
Hiraoka, Y.20
Augustin, M.21
Korthaus, D.22
Wattler, S.23
Wabnitz, P.24
Dickneite, C.25
Lampel, S.26
Boehme, F.27
Peraus, G.28
Popp, A.29
Rudelius, M.30
Schlegel, J.31
Fuchs, H.32
De Angelis, M.H.33
Schiavo, G.34
Shima, D.T.35
Russ, A.P.36
Stumm, G.37
Martin, J.E.38
Fisher, E.M.C.39
more..
-
98
-
-
0032489870
-
Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein
-
DOI 10.1083/jcb.141.1.51
-
A. Harada, Y. Takei, Y. Kanai, Y. Tanaka, S. Nonaka, and N. Hirokawa Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein J Cell Biol 141 1998 51 59 (Pubitemid 28182640)
-
(1998)
Journal of Cell Biology
, vol.141
, Issue.1
, pp. 51-59
-
-
Harada, A.1
Takei, Y.2
Kanai, Y.3
Tanaka, Y.4
Nonaka, S.5
Hirokawa, N.6
-
99
-
-
2542421751
-
Dynein motors transport activated Trks to promote survival of target-dependent neurons
-
DOI 10.1038/nn1242
-
H.M. Heerssen, M.F. Pazyra, and R.A. Segal Dynein motors transport activated Trks to promote survival of target-dependent neurons Nat Neurosci 7 2004 596 604 (Pubitemid 38691898)
-
(2004)
Nature Neuroscience
, vol.7
, Issue.6
, pp. 596-604
-
-
Heerssen, H.M.1
Pazyra, M.F.2
Segal, R.A.3
-
101
-
-
58149385090
-
Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin
-
L.S. Her, and L.S. Goldstein Enhanced sensitivity of striatal neurons to axonal transport defects induced by mutant huntingtin J Neurosci 28 2008 13662 13672
-
(2008)
J Neurosci
, vol.28
, pp. 13662-13672
-
-
Her, L.S.1
Goldstein, L.S.2
-
102
-
-
0032559260
-
Kinesin and dynein superfamily proteins and the mechanism of organelle transport
-
DOI 10.1126/science.279.5350.519
-
N. Hirokawa Kinesin and dynein superfamily proteins and the mechanism of organelle transport Science 279 1998 519 526 (Pubitemid 28067273)
-
(1998)
Science
, vol.279
, Issue.5350
, pp. 519-526
-
-
Hirokawa, N.1
-
103
-
-
78449269612
-
Molecular motors in neurons: Transport mechanisms and roles in brain function, development, and disease
-
N. Hirokawa, S. Niwa, and Y. Tanaka Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease Neuron 68 2010 610 638
-
(2010)
Neuron
, vol.68
, pp. 610-638
-
-
Hirokawa, N.1
Niwa, S.2
Tanaka, Y.3
-
104
-
-
30544452263
-
The axonal transport of mitochondria
-
DOI 10.1242/jcs.02745
-
P.J. Hollenbeck, and W.M. Saxton The axonal transport of mitochondria J Cell Sci 118 2005 5411 5419 (Pubitemid 43079283)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.23
, pp. 5411-5419
-
-
Hollenbeck, P.J.1
Saxton, W.M.2
-
105
-
-
0035965256
-
Beta III spectrin binds to the Arp1 subunit of dynactin
-
E.A. Holleran, L.A. Ligon, M. Tokito, M.C. Stankewich, J.S. Morrow, and E.L. Holzbaur Beta III spectrin binds to the Arp1 subunit of dynactin J Biol Chem 276 2001 36598 36605
-
(2001)
J Biol Chem
, vol.276
, pp. 36598-36605
-
-
Holleran, E.A.1
Ligon, L.A.2
Tokito, M.3
Stankewich, M.C.4
Morrow, J.S.5
Holzbaur, E.L.6
-
107
-
-
0035422303
-
Mammalian golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes
-
DOI 10.1093/emboj/20.15.4041
-
C.C. Hoogenraad, A. Akhmanova, S.A. Howell, B.R. Dortland, C.I. De Zeeuw, and R. Willemsen Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes EMBO J 20 2001 4041 4054 (Pubitemid 32751821)
-
(2001)
EMBO Journal
, vol.20
, Issue.15
, pp. 4041-4054
-
-
Hoogenraad, C.C.1
Akhmanova, A.2
Howell, S.A.3
Dortland, B.R.4
De Zeeuw, C.I.5
Willemsen, R.6
Visser, P.7
Grosveld, F.8
Galjart, N.9
-
108
-
-
0037161744
-
HDAC6 is a microtubule-associated deacetylase
-
DOI 10.1038/417455a
-
C. Hubbert, A. Guardiola, R. Shao, Y. Kawaguchi, A. Ito, and A. Nixon HDAC6 is a microtubule-associated deacetylase Nature 417 2002 455 458 (Pubitemid 34563539)
-
(2002)
Nature
, vol.417
, Issue.6887
, pp. 455-458
-
-
Hubbert, C.1
Guardiola, A.2
Shao, R.3
Kawaguchi, Y.4
Ito, A.5
Nixon, A.6
Yoshida, M.7
Wang, X.-F.8
Yao, T.-P.9
-
109
-
-
39149132089
-
ESCRT complexes and the biogenesis of multivesicular bodies
-
J.H. Hurley ESCRT complexes and the biogenesis of multivesicular bodies Curr Opin Cell Biol 20 2008 4 11
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 4-11
-
-
Hurley, J.H.1
-
110
-
-
31744441984
-
Spectrin mutations cause spinocerebellar ataxia type 5
-
DOI 10.1038/ng1728, PII NG1728
-
Y. Ikeda, K.A. Dick, M.R. Weatherspoon, D. Gincel, K.R. Armbrust, and J.C. Dalton Spectrin mutations cause spinocerebellar ataxia type 5 Nat Genet 38 2006 184 190 (Pubitemid 43177231)
-
(2006)
Nature Genetics
, vol.38
, Issue.2
, pp. 184-190
-
-
Ikeda, Y.1
Dick, K.A.2
Weatherspoon, M.R.3
Gincel, D.4
Armbrust, K.R.5
Dalton, J.C.6
Stevanin, G.7
Durr, A.8
Zuhlke, C.9
Burk, K.10
Clark, H.B.11
Brice, A.12
Rothstein, J.D.13
Schut, L.J.14
Day, J.W.15
Ranum, L.P.W.16
-
111
-
-
74049164709
-
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
-
H. Ilieva, M. Polymenidou, and D.W. Cleveland Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond J Cell Biol 187 2009 761 772
-
(2009)
J Cell Biol
, vol.187
, pp. 761-772
-
-
Ilieva, H.1
Polymenidou, M.2
Cleveland, D.W.3
-
112
-
-
50449101429
-
Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
-
H.S. Ilieva, K. Yamanaka, S. Malkmus, O. Kakinohana, T. Yaksh, and M. Marsala Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death Proc Natl Acad Sci U S A 105 2008 12599 12604
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 12599-12604
-
-
Ilieva, H.S.1
Yamanaka, K.2
Malkmus, S.3
Kakinohana, O.4
Yaksh, T.5
Marsala, M.6
-
113
-
-
40449139980
-
The itinerary of autophagosomes: From peripheral formation to kiss-and-run fusion with lysosomes
-
DOI 10.1111/j.1600-0854.2008.00701.x
-
L. Jahreiss, F.M. Menzies, and D.C. Rubinsztein The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes Traffic 9 2008 574 587 (Pubitemid 351351616)
-
(2008)
Traffic
, vol.9
, Issue.4
, pp. 574-587
-
-
Jahreiss, L.1
Menzies, F.M.2
Rubinsztein, D.C.3
-
114
-
-
0032500599
-
Binding of α-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation
-
DOI 10.1074/jbc.273.41.26292
-
P.H. Jensen, M.S. Nielsen, R. Jakes, C.G. Dotti, and M. Goedert Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation J Biol Chem 273 1998 26292 26294 (Pubitemid 28471629)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.41
, pp. 26292-26294
-
-
Jensen, P.H.1
Nielsen, M.S.2
Jakes, R.3
Dotti, C.G.4
Goedert, M.5
-
115
-
-
58149393853
-
Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome
-
Q. Jiang, Y. Ren, and J. Feng Direct binding with histone deacetylase 6 mediates the reversible recruitment of parkin to the centrosome J Neurosci 28 2008 12993 13002
-
(2008)
J Neurosci
, vol.28
, pp. 12993-13002
-
-
Jiang, Q.1
Ren, Y.2
Feng, J.3
-
116
-
-
33847003020
-
Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin
-
M. Johansson, N. Rocha, W. Zwart, I. Jordens, L. Janssen, and C. Kuijl Activation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrin J Cell Biol 176 2007 459 471
-
(2007)
J Cell Biol
, vol.176
, pp. 459-471
-
-
Johansson, M.1
Rocha, N.2
Zwart, W.3
Jordens, I.4
Janssen, L.5
Kuijl, C.6
-
117
-
-
0035975946
-
The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors
-
DOI 10.1016/S0960-9822(01)00531-0
-
I. Jordens, M. Fernandez-Borja, M. Marsman, S. Dusseljee, L. Janssen, and J. Calafat The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors Curr Biol 11 2001 1680 1685 (Pubitemid 33037779)
-
(2001)
Current Biology
, vol.11
, Issue.21
, pp. 1680-1685
-
-
Jordens, I.1
Fernandez-Borja, M.2
Marsman, M.3
Dusseljee, S.4
Janssen, L.5
Calafat, J.6
Janssen, H.7
Wubbolts, R.8
Neefjes, J.9
-
118
-
-
0028904293
-
Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein
-
Y.S. Jou, and R.M. Myers Evidence from antibody studies that the CAG repeat in the Huntington disease gene is expressed in the protein Hum Mol Genet 4 1995 465 469
-
(1995)
Hum Mol Genet
, vol.4
, pp. 465-469
-
-
Jou, Y.S.1
Myers, R.M.2
-
119
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
DOI 10.1038/ng.132, PII NG132
-
E. Kabashi, P.N. Valdmanis, P. Dion, D. Spiegelman, B.J. McConkey, and C. Vande Velde TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis Nat Genet 40 2008 572 574 (Pubitemid 351601218)
-
(2008)
Nature Genetics
, vol.40
, Issue.5
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
Velde, C.V.6
Bouchard, J.-P.7
Lacomblez, L.8
Pochigaeva, K.9
Salachas, F.10
Pradat, P.-F.11
Camu, W.12
Meininger, V.13
Dupre, N.14
Rouleau, G.A.15
-
120
-
-
0033636136
-
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I
-
A. Kamal, G.B. Stokin, Z. Yang, C.H. Xia, and L.S. Goldstein Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I Neuron 28 2000 449 459
-
(2000)
Neuron
, vol.28
, pp. 449-459
-
-
Kamal, A.1
Stokin, G.B.2
Yang, Z.3
Xia, C.H.4
Goldstein, L.S.5
-
121
-
-
70450228589
-
Regulators of the cytoplasmic dynein motor
-
J.R. Kardon, and R.D. Vale Regulators of the cytoplasmic dynein motor Nat Rev Mol Cell Biol 10 2009 854 865
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 854-865
-
-
Kardon, J.R.1
Vale, R.D.2
-
122
-
-
0028806377
-
Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex
-
S. Karki, and E.L. Holzbaur Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex J Biol Chem 270 1995 28806 28811
-
(1995)
J Biol Chem
, vol.270
, pp. 28806-28811
-
-
Karki, S.1
Holzbaur, E.L.2
-
123
-
-
33751339785
-
Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration
-
DOI 10.1523/JNEUROSCI.3032-06.2006
-
M. Katsuno, H. Adachi, M. Minamiyama, M. Waza, K. Tokui, and H. Banno Reversible disruption of dynactin 1-mediated retrograde axonal transport in polyglutamine-induced motor neuron degeneration J Neurosci 26 2006 12106 12117 (Pubitemid 44808377)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.47
, pp. 12106-12117
-
-
Katsuno, M.1
Adachi, H.2
Minamiyama, M.3
Waza, M.4
Tokui, K.5
Banno, H.6
Suzuki, K.7
Onoda, Y.8
Tanaka, F.9
Doyu, M.10
Sobue, G.11
-
124
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
DOI 10.1016/S0092-8674(03)00939-5
-
Y. Kawaguchi, J.J. Kovacs, A. McLaurin, J.M. Vance, A. Ito, and T.P. Yao The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress Cell 115 2003 727 738 (Pubitemid 38030301)
-
(2003)
Cell
, vol.115
, Issue.6
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.-P.6
-
125
-
-
71449086017
-
Dynein dysfunction induces endocytic pathology accompanied by an increase in Rab GTPases: A potential mechanism underlying age-dependent endocytic dysfunction
-
N. Kimura, M. Inoue, S. Okabayashi, F. Ono, and T. Negishi Dynein dysfunction induces endocytic pathology accompanied by an increase in Rab GTPases: a potential mechanism underlying age-dependent endocytic dysfunction J Biol Chem 284 2009 31291 31302
-
(2009)
J Biol Chem
, vol.284
, pp. 31291-31302
-
-
Kimura, N.1
Inoue, M.2
Okabayashi, S.3
Ono, F.4
Negishi, T.5
-
126
-
-
35148816608
-
Endosomal accumulation of GM1 ganglioside-bound amyloid β-protein in neurons of aged monkey brains
-
DOI 10.1097/WNR.0b013e3282f0d2ab, PII 0000175620071029000007
-
N. Kimura, and K. Yanagisawa Endosomal accumulation of GM1 ganglioside-bound amyloid beta-protein in neurons of aged monkey brains Neuroreport 18 2007 1669 1673 (Pubitemid 47549131)
-
(2007)
NeuroReport
, vol.18
, Issue.16
, pp. 1669-1673
-
-
Kimura, N.1
Yanagisawa, K.2
-
127
-
-
0033789351
-
Dynactin increases the processivity of the cytoplasmic dynein motor
-
S.J. King, and T.A. Schroer Dynactin increases the processivity of the cytoplasmic dynein motor Nat Cell Biol 2 2000 20 24
-
(2000)
Nat Cell Biol
, vol.2
, pp. 20-24
-
-
King, S.J.1
Schroer, T.A.2
-
128
-
-
0032573114
-
Cytoplasmic dynein contains a family of differentially expressed light chains
-
DOI 10.1021/bi9810813
-
S.M. King, E. Barbarese, J.F. Dillman 3rd, S.E. Benashski, K.T. Do, and R.S. Patel-King Cytoplasmic dynein contains a family of differentially expressed light chains Biochemistry 37 1998 15033 15041 (Pubitemid 28503230)
-
(1998)
Biochemistry
, vol.37
, Issue.43
, pp. 15033-15041
-
-
King, S.M.1
Barbarese, E.2
Dillman III, J.F.3
Benashski, S.E.4
Do, K.T.5
Patel-King, R.S.6
Pfister, K.K.7
-
129
-
-
77950908040
-
Clearance of mutant proteins as a therapeutic target in neurodegenerative diseases
-
D. Krainc Clearance of mutant proteins as a therapeutic target in neurodegenerative diseases Arch Neurol 67 2010 388 392
-
(2010)
Arch Neurol
, vol.67
, pp. 388-392
-
-
Krainc, D.1
-
130
-
-
51649124062
-
Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations
-
P. Kuhnlein, A.D. Sperfeld, B. Vanmassenhove, V. Van Deerlin, V.M. Lee, and J.Q. Trojanowski Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations Arch Neurol 65 2008 1185 1189
-
(2008)
Arch Neurol
, vol.65
, pp. 1185-1189
-
-
Kuhnlein, P.1
Sperfeld, A.D.2
Vanmassenhove, B.3
Van Deerlin, V.4
Lee, V.M.5
Trojanowski, J.Q.6
-
131
-
-
0036759121
-
Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau
-
V. Kunzi, M. Glatzel, M.Y. Nakano, U.F. Greber, F. Van Leuven, and A. Aguzzi Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau J Neurosci 22 2002 7471 7477 (Pubitemid 35386347)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.17
, pp. 7471-7477
-
-
Kunzi, V.1
Glatzel, M.2
Nakano, M.Y.3
Greber, U.F.4
Van Leuven, F.5
Aguzzi, A.6
-
132
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
T.J. Kwiatkowski Jr., D.A. Bosco, A.L. Leclerc, E. Tamrazian, C.R. Vanderburg, and C. Russ Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis Science 323 2009 1205 1208
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski Jr., T.J.1
Bosco, D.A.2
Leclerc, A.L.3
Tamrazian, E.4
Vanderburg, C.R.5
Russ, C.6
-
133
-
-
0026529245
-
Caudate nucleus pathology in Parkinson's disease: Ultrastructural and biochemical findings in biopsy material
-
B. Lach, D. Grimes, B. Benoit, and A. Minkiewicz-Janda Caudate nucleus pathology in Parkinson's disease: ultrastructural and biochemical findings in biopsy material Acta Neuropathol 83 1992 352 360
-
(1992)
Acta Neuropathol
, vol.83
, pp. 352-360
-
-
Lach, B.1
Grimes, D.2
Benoit, B.3
Minkiewicz-Janda, A.4
-
134
-
-
0035575858
-
Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic Murine model of Huntington's disease
-
G.A. Laforet, E. Sapp, K. Chase, C. McIntyre, F.M. Boyce, and M. Campbell Changes in cortical and striatal neurons predict behavioral and electrophysiological abnormalities in a transgenic murine model of Huntington's disease J Neurosci 21 2001 9112 9123 (Pubitemid 33096854)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.23
, pp. 9112-9123
-
-
Laforet, G.A.1
Sapp, E.2
Chase, K.3
McIntyre, C.4
Boyce, F.M.5
Campbell, M.6
Cadigan, B.A.7
Warzecki, L.8
Tagle, D.A.9
Reddy, P.H.10
Cepeda, C.11
Calvert, C.R.12
Jokel, E.S.13
Klapstein, G.J.14
Ariano, M.A.15
Levine, M.S.16
DiFiglia, M.17
Aronin, N.18
-
135
-
-
62149141328
-
Rethinking ALS: The FUS about TDP-43
-
C. Lagier-Tourenne, and D.W. Cleveland Rethinking ALS: the FUS about TDP-43 Cell 136 2009 1001 1004
-
(2009)
Cell
, vol.136
, pp. 1001-1004
-
-
Lagier-Tourenne, C.1
Cleveland, D.W.2
-
136
-
-
38449097283
-
glued causes dysfunction of dynactin in mice
-
DOI 10.1523/JNEUROSCI.4226-07.2007
-
C. Lai, X. Lin, J. Chandran, H. Shim, W.J. Yang, and H. Cai The G59S mutation in p150(glued) causes dysfunction of dynactin in mice J Neurosci 27 2007 13982 13990 (Pubitemid 351377874)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.51
, pp. 13982-13990
-
-
Lai, C.1
Lin, X.2
Chandran, J.3
Shim, H.4
Yang, W.-J.5
Cai, H.6
-
137
-
-
34447123766
-
Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis
-
DOI 10.1523/JNEUROSCI.4599-06.2007
-
D. Laifenfeld, L.J. Patzek, D.L. McPhie, Y. Chen, Y. Levites, and A.M. Cataldo Rab5 mediates an amyloid precursor protein signaling pathway that leads to apoptosis J Neurosci 27 2007 7141 7153 (Pubitemid 47037567)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.27
, pp. 7141-7153
-
-
Laifenfeld, D.1
Patzek, L.J.2
McPhie, D.L.3
Chen, Y.4
Levites, Y.5
Cataldo, A.M.6
Neve, R.L.7
-
138
-
-
39849107361
-
Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking
-
DOI 10.1523/JNEUROSCI.4231-07.2008
-
F.M. Laird, M.H. Farah, S. Ackerley, A. Hoke, N. Maragakis, and J.D. Rothstein Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking J Neurosci 28 2008 1997 2005 (Pubitemid 351317634)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.9
, pp. 1997-2005
-
-
Laird, F.M.1
Farah, M.H.2
Ackerley, S.3
Hoke, A.4
Maragakis, N.5
Rothstein, J.D.6
Griffin, J.7
Price, D.L.8
Martin, L.J.9
Wong, P.C.10
-
139
-
-
0037198698
-
Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration
-
DOI 10.1016/S0896-6273(02)00696-7
-
B.H. LaMonte, K.E. Wallace, B.A. Holloway, S.S. Shelly, J. Ascano, and M. Tokito Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration Neuron 34 2002 715 727 (Pubitemid 34628735)
-
(2002)
Neuron
, vol.34
, Issue.5
, pp. 715-727
-
-
LaMonte, B.H.1
Wallace, K.E.2
Holloway, B.A.3
Shelly, S.S.4
Ascano, J.5
Tokito, M.6
Van Winkle, T.7
Howland, D.S.8
Holzbaur, E.L.F.9
-
140
-
-
0025800526
-
Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy
-
A.R. La Spada, E.M. Wilson, D.B. Lubahn, A.E. Harding, and K.H. Fischbeck Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy Nature 352 1991 77 79 (Pubitemid 21896702)
-
(1991)
Nature
, vol.352
, Issue.6330
, pp. 77-79
-
-
La Spada, A.R.1
Wilson, E.M.2
Lubahn, D.B.3
Harding, A.E.4
Fischbeck, K.H.5
-
141
-
-
0037111837
-
Evidence that synaptically released β-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice
-
O. Lazarov, M. Lee, D.A. Peterson, and S.S. Sisodia Evidence that synaptically released beta-amyloid accumulates as extracellular deposits in the hippocampus of transgenic mice J Neurosci 22 2002 9785 9793 (Pubitemid 35332862)
-
(2002)
Journal of Neuroscience
, vol.22
, Issue.22
, pp. 9785-9793
-
-
Lazarov, O.1
Lee, M.2
Peterson, D.A.3
Sisodia, S.S.4
-
142
-
-
20044396527
-
Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: Revisited
-
DOI 10.1523/JNEUROSCI.3089-04.2005
-
O. Lazarov, G.A. Morfini, E.B. Lee, M.H. Farah, A. Szodorai, and S.R. DeBoer Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited J Neurosci 25 2005 2386 2395 (Pubitemid 40322280)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.9
, pp. 2386-2395
-
-
Lazarov, O.1
Morfini, G.A.2
Lee, E.B.3
Farah, M.H.4
Szodorai, A.5
DeBoer, S.R.6
Koliatsos, V.E.7
Kins, S.8
Lee, V.M.-Y.9
Wong, P.C.10
Price, D.L.11
Brady, S.T.12
Sisodia, S.S.13
-
143
-
-
33845656077
-
Impairment of microtubule-dependent trafficking by overexpression of α-synuclein
-
DOI 10.1111/j.1460-9568.2006.05210.x
-
H.J. Lee, F. Khoshaghideh, S. Lee, and S.J. Lee Impairment of microtubule-dependent trafficking by overexpression of alpha-synuclein Eur J Neurosci 24 2006 3153 3162 (Pubitemid 44952647)
-
(2006)
European Journal of Neuroscience
, vol.24
, Issue.11
, pp. 3153-3162
-
-
Lee, H.-J.1
Khoshaghideh, F.2
Lee, S.3
Lee, S.-J.4
-
144
-
-
34548492271
-
ESCRT-III Dysfunction Causes Autophagosome Accumulation and Neurodegeneration
-
DOI 10.1016/j.cub.2007.07.029, PII S0960982207017071
-
J.A. Lee, A. Beigneux, S.T. Ahmad, S.G. Young, and F.B. Gao ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration Curr Biol 17 2007 1561 1567 (Pubitemid 47380392)
-
(2007)
Current Biology
, vol.17
, Issue.18
, pp. 1561-1567
-
-
Lee, J.-A.1
Beigneux, A.2
Ahmad, S.T.3
Young, S.G.4
Gao, F.-B.5
-
145
-
-
66649128231
-
P150/glued modifies nuclear estrogen receptor function
-
S.J. Lee, C. Chae, and M.M. Wang p150/glued modifies nuclear estrogen receptor function Mol Endocrinol 23 2009 620 629
-
(2009)
Mol Endocrinol
, vol.23
, pp. 620-629
-
-
Lee, S.J.1
Chae, C.2
Wang, M.M.3
-
148
-
-
0028797783
-
Identification and characterization of a spinal muscular atrophy-determining gene
-
S. Lefebvre, L. Burglen, S. Reboullet, O. Clermont, P. Burlet, and L. Viollet Identification and characterization of a spinal muscular atrophy-determining gene Cell 80 1995 155 165
-
(1995)
Cell
, vol.80
, pp. 155-165
-
-
Lefebvre, S.1
Burglen, L.2
Reboullet, S.3
Clermont, O.4
Burlet, P.5
Viollet, L.6
-
149
-
-
33644507718
-
Cytoplasmic dynein/dynactin function and dysfunction in motor neurons
-
DOI 10.1016/j.ijdevneu.2005.11.013, PII S0736574805001449, Neural Signal Transduction in Health and Disease - Cytokinesd, Mitochondrial Dysfunction and Transport Processes
-
J.R. Levy, and E.L. Holzbaur Cytoplasmic dynein/dynactin function and
-
(2006)
International Journal of Developmental Neuroscience
, vol.24
, Issue.2-3
, pp. 103-111
-
-
Levy, J.R.1
Holzbaur, E.L.F.2
-
150
-
-
33644551565
-
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation
-
J.R. Levy, C.J. Sumner, J.P. Caviston, M.K. Tokito, S. Ranganathan, and L.A. Ligon A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation J Cell Biol 172 2006 733 745
-
(2006)
J Cell Biol
, vol.172
, pp. 733-745
-
-
Levy, J.R.1
Sumner, C.J.2
Caviston, J.P.3
Tokito, M.K.4
Ranganathan, S.5
Ligon, L.A.6
-
151
-
-
17844399774
-
Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons
-
DOI 10.1097/00001756-200504250-00002
-
L.A. Ligon, B.H. LaMonte, K.E. Wallace, N. Weber, R.G. Kalb, and E.L. Holzbaur Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons Neuroreport 16 2005 533 536 (Pubitemid 40586076)
-
(2005)
NeuroReport
, vol.16
, Issue.6
, pp. 533-536
-
-
Ligon, L.A.1
LaMonte, B.H.2
Wallace, K.E.3
Weber, N.4
Kalb, R.G.5
Holzbaur, E.L.F.6
-
152
-
-
0026601916
-
Immunolocalization of cytoplasmic dynein to lysosomes in cultured cells
-
S.X. Lin, and C.A. Collins Immunolocalization of cytoplasmic dynein to lysosomes in cultured cells J Cell Sci 101 Pt 1 1992 125 137
-
(1992)
J Cell Sci
, vol.101
, Issue.PART 1
, pp. 125-137
-
-
Lin, S.X.1
Collins, C.A.2
-
153
-
-
72149087091
-
Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein
-
X. Lin, L. Parisiadou, X.L. Gu, L. Wang, H. Shim, and L. Sun Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein Neuron 64 2009 807 827
-
(2009)
Neuron
, vol.64
, pp. 807-827
-
-
Lin, X.1
Parisiadou, L.2
Gu, X.L.3
Wang, L.4
Shim, H.5
Sun, L.6
-
154
-
-
77950564431
-
Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila
-
D.N. Lorenzo, M.G. Li, S.E. Mische, K.R. Armbrust, L.P. Ranum, and T.S. Hays Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila J Cell Biol 189 2010 143 158
-
(2010)
J Cell Biol
, vol.189
, pp. 143-158
-
-
Lorenzo, D.N.1
Li, M.G.2
Mische, S.E.3
Armbrust, K.R.4
Ranum, L.P.5
Hays, T.S.6
-
155
-
-
35649028013
-
Interaction of tau protein with the dynactin complex
-
DOI 10.1038/sj.emboj.7601878, PII 7601878
-
E. Magnani, J. Fan, L. Gasparini, M. Golding, M. Williams, and G. Schiavo Interaction of tau protein with the dynactin complex EMBO J 26 2007 4546 4554 (Pubitemid 350036634)
-
(2007)
EMBO Journal
, vol.26
, Issue.21
, pp. 4546-4554
-
-
Magnani, E.1
Fan, J.2
Gasparini, L.3
Golding, M.4
Williams, M.5
Schiavo, G.6
Goedert, M.7
Amos, L.A.8
Spillantini, M.G.9
-
156
-
-
1342325553
-
Cytoplasmic dynein functions as a gear in response to load
-
DOI 10.1038/nature02293
-
R. Mallik, B.C. Carter, S.A. Lex, S.J. King, and S.P. Gross Cytoplasmic dynein functions as a gear in response to load Nature 427 2004 649 652 (Pubitemid 38248486)
-
(2004)
Nature
, vol.427
, Issue.6975
, pp. 649-652
-
-
Mallik, R.1
Carter, B.C.2
Lex, S.A.3
King, S.J.4
Gross, S.P.5
-
157
-
-
9244232349
-
Molecular motors: Strategies to get along
-
R. Mallik, and S.P. Gross Molecular motors: strategies to get along Curr Biol 14 2004 R971 R982
-
(2004)
Curr Biol
, vol.14
-
-
Mallik, R.1
Gross, S.P.2
-
158
-
-
33845348169
-
Expanding the phenotypes of the Pro56Ser VAPB mutation: Proximal SMA with dysautonomia
-
DOI 10.1002/mus.20657
-
V.D. Marques, A.A. Barreira, M.B. Davis, P.M. Abou-Sleiman, W.A. Silva Jr., and M.A. Zago Expanding the phenotypes of the Pro56Ser VAPB mutation: proximal SMA with dysautonomia Muscle Nerve 34 2006 731 739 (Pubitemid 44877556)
-
(2006)
Muscle and Nerve
, vol.34
, Issue.6
, pp. 731-739
-
-
Marques, V.D.1
Barreira, A.A.2
Davis, M.B.3
Abou-Sleiman, P.M.4
Silva Jr., W.A.5
Zago, M.A.6
Sobreira, C.7
Fazan, V.8
Marques Jr., W.9
-
159
-
-
77951665859
-
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
-
M. Martinez-Vicente, Z. Talloczy, E. Wong, G. Tang, H. Koga, and S. Kaushik Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease Nat Neurosci 13 2010 567 576
-
(2010)
Nat Neurosci
, vol.13
, pp. 567-576
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Wong, E.3
Tang, G.4
Koga, H.5
Kaushik, S.6
-
160
-
-
0036902478
-
Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex
-
DOI 10.1038/ncb891
-
T. Matanis, A. Akhmanova, P. Wulf, E. Del Nery, T. Weide, and T. Stepanova Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex Nat Cell Biol 4 2002 986 992 (Pubitemid 35469430)
-
(2002)
Nature Cell Biology
, vol.4
, Issue.12
, pp. 986-992
-
-
Matanis, T.1
Akhmanova, A.2
Wulf, P.3
Del Nery, E.4
Weide, T.5
Stepanova, T.6
Galjart, N.7
Grosveld, F.8
Goud, B.9
De Zeeuw, C.I.10
Barnekow, A.11
Hoogenraad, C.C.12
-
161
-
-
77951181836
-
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
-
N. Matsuda, S. Sato, K. Shiba, K. Okatsu, K. Saisho, and C.A. Gautier PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy J Cell Biol 189 2010 211 221
-
(2010)
J Cell Biol
, vol.189
, pp. 211-221
-
-
Matsuda, N.1
Sato, S.2
Shiba, K.3
Okatsu, K.4
Saisho, K.5
Gautier, C.A.6
-
162
-
-
77950686629
-
Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation
-
B.A. McCray, E. Skordalakes, and J.P. Taylor Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation Hum Mol Genet 19 2010 1033 1047
-
(2010)
Hum Mol Genet
, vol.19
, pp. 1033-1047
-
-
McCray, B.A.1
Skordalakes, E.2
Taylor, J.P.3
-
163
-
-
0034106888
-
Basal ganglia and cerebellar loops: Motor and cognitive circuits
-
DOI 10.1016/S0165-0173(99)00040-5, PII S0165017399000405
-
F.A. Middleton, and P.L. Strick Basal ganglia and cerebellar loops: motor and cognitive circuits Brain Res Brain Res Rev 31 2000 236 250 (Pubitemid 30136179)
-
(2000)
Brain Research Reviews
, vol.31
, Issue.2-3
, pp. 236-250
-
-
Middleton, F.A.1
Strick, P.L.2
-
164
-
-
0037115599
-
Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells
-
DOI 10.1242/jcs.00168
-
A. Mikami, S.H. Tynan, T. Hama, K. Luby-Phelps, T. Saito, and J.E. Crandall Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cells J Cell Sci 115 2002 4801 4808 (Pubitemid 36054633)
-
(2002)
Journal of Cell Science
, vol.115
, Issue.24
, pp. 4801-4808
-
-
Mikami, A.1
Tynan, S.H.2
Hama, T.3
Luby-Phelps, K.4
Saito, T.5
Crandall, J.E.6
Besharse, J.C.7
Valle, R.B.8
-
165
-
-
77955396350
-
SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: Genotype-phenotype correlations
-
S. Millecamps, F. Salachas, C. Cazeneuve, P. Gordon, B. Bricka, and A. Camuzat SOD1, ANG, VAPB, TARDBP, and FUS mutations in familial amyotrophic lateral sclerosis: genotype-phenotype correlations J Med Genet 47 2010 554 560
-
(2010)
J Med Genet
, vol.47
, pp. 554-560
-
-
Millecamps, S.1
Salachas, F.2
Cazeneuve, C.3
Gordon, P.4
Bricka, B.5
Camuzat, A.6
-
166
-
-
3242875557
-
Axonal mitochondrial transport and potential are correlated
-
DOI 10.1242/jcs.01130
-
K.E. Miller, and M.P. Sheetz Axonal mitochondrial transport and potential are correlated J Cell Sci 117 2004 2791 2804 (Pubitemid 38997261)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2791-2804
-
-
Miller, K.E.1
Sheetz, M.P.2
-
167
-
-
77949801029
-
Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex
-
A. Misko, S. Jiang, I. Wegorzewska, J. Milbrandt, and R.H. Baloh Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex J Neurosci 30 2010 4232 4240
-
(2010)
J Neurosci
, vol.30
, pp. 4232-4240
-
-
Misko, A.1
Jiang, S.2
Wegorzewska, I.3
Milbrandt, J.4
Baloh, R.H.5
-
168
-
-
33847770318
-
1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C
-
DOI 10.1073/pnas.0611231104
-
G. Morfini, G. Pigino, K. Opalach, Y. Serulle, J.E. Moreira, and M. Sugimori 1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C Proc Natl Acad Sci U S A 104 2007 2442 2447 (Pubitemid 46391416)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.7
, pp. 2442-2447
-
-
Morfini, G.1
Pigino, G.2
Opalach, K.3
Serulle, Y.4
Moreira, J.E.5
Sugimori, M.6
Llinas, R.R.7
Brady, S.T.8
-
169
-
-
33745520772
-
JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport
-
DOI 10.1038/nn1717, PII N1717
-
G. Morfini, G. Pigino, G. Szebenyi, Y. You, S. Pollema, and S.T. Brady JNK mediates pathogenic effects of polyglutamine-expanded androgen receptor on fast axonal transport Nat Neurosci 9 2006 907 916 (Pubitemid 43980505)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.7
, pp. 907-916
-
-
Morfini, G.1
Pigino, G.2
Szebenyi, G.3
You, Y.4
Pollema, S.5
Brady, S.T.6
-
170
-
-
70350455072
-
Axonal transport defects in neurodegenerative diseases
-
G.A. Morfini, M. Burns, L.I. Binder, N.M. Kanaan, N. LaPointe, and D.A. Bosco Axonal transport defects in neurodegenerative diseases J Neurosci 29 2009 12776 12786
-
(2009)
J Neurosci
, vol.29
, pp. 12776-12786
-
-
Morfini, G.A.1
Burns, M.2
Binder, L.I.3
Kanaan, N.M.4
Lapointe, N.5
Bosco, D.A.6
-
171
-
-
0347993816
-
c in peripheral nerve
-
K.L. Moya, R. Hassig, C. Creminon, I. Laffont, and L. Di Giamberardino Enhanced detection and retrograde axonal transport of PrPc in peripheral nerve J Neurochem 88 2004 155 160 (Pubitemid 38030218)
-
(2004)
Journal of Neurochemistry
, vol.88
, Issue.1
, pp. 155-160
-
-
Moya, K.L.1
Hassig, R.2
Creminon, C.3
Laffont, I.4
Di Giamberardino, L.5
-
172
-
-
4143084861
-
Point mutations of the p150 subunit of dynactin (DCTN1) gene ALS
-
C. Munch, R. Sedlmeier, T. Meyer, V. Homberg, A.D. Sperfeld, and A. Kurt Point mutations of the p150 subunit of dynactin (DCTN1) gene in ALS Neurology 63 2004 724 726 (Pubitemid 39100836)
-
(2004)
Neurology
, vol.63
, Issue.4
, pp. 724-726
-
-
Munch, C.1
Sedlmeier, R.2
Meyer, T.3
Homberg, V.4
Sperfeld, A.D.5
Kurt, A.6
Prudlo, J.7
Peraus, G.8
Hanemann, C.O.9
Stumm, G.10
Ludolph, A.C.11
-
173
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
D. Narendra, A. Tanaka, D.F. Suen, and R.J. Youle Parkin is recruited selectively to impaired mitochondria and promotes their autophagy J Cell Biol 183 2008 795 803
-
(2008)
J Cell Biol
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
174
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
D.P. Narendra, S.M. Jin, A. Tanaka, D.F. Suen, C.A. Gautier, and J. Shen PINK1 is selectively stabilized on impaired mitochondria to activate Parkin PLoS Biol 8 2010 e1000298
-
(2010)
PLoS Biol
, vol.8
, pp. 1000298
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
-
175
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
DOI 10.1126/science.1134108
-
M. Neumann, D.M. Sampathu, L.K. Kwong, A.C. Truax, M.C. Micsenyi, and T.T. Chou Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 2006 130 133 (Pubitemid 44547757)
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.-Y.19
-
177
-
-
6344257200
-
A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis
-
DOI 10.1086/425287
-
A.L. Nishimura, M. Mitne-Neto, H.C. Silva, A. Richieri-Costa, S. Middleton, and D. Cascio A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis Am J Hum Genet 75 2004 822 831 (Pubitemid 39390489)
-
(2004)
American Journal of Human Genetics
, vol.75
, Issue.5
, pp. 822-831
-
-
Nishimura, A.L.1
Mitne-Neto, M.2
Silva, H.C.A.3
Richieri-Costa, A.4
Middleton, S.5
Cascio, D.6
Kok, F.7
Oliveira, J.R.M.8
Gillingwater, T.9
Webb, J.10
Skehel, P.11
Zatz, M.12
-
178
-
-
34548851476
-
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
-
DOI 10.1083/jcb.200611128
-
J.A. Olzmann, L. Li, M.V. Chudaev, J. Chen, F.A. Perez, and R.D. Palmiter Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6 J Cell Biol 178 2007 1025 1038 (Pubitemid 47443324)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.6
, pp. 1025-1038
-
-
Olzmann, J.A.1
Li, A.2
Chudaev, M.V.3
Chen, J.4
Perez, F.A.5
Palmiter, R.D.6
Chin, L.-S.7
-
179
-
-
78649842747
-
A cytoplasmic dynein tail mutation impairs motor processivity
-
K.M. Ori-McKenney, J. Xu, S.P. Gross, and R.B. Vallee A cytoplasmic dynein tail mutation impairs motor processivity Nat Cell Biol 12 2010 1228 1234
-
(2010)
Nat Cell Biol
, vol.12
, pp. 1228-1234
-
-
Ori-Mckenney, K.M.1
Xu, J.2
Gross, S.P.3
Vallee, R.B.4
-
180
-
-
0041308082
-
ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics
-
DOI 10.1093/hmg/ddg184
-
A. Otomo, S. Hadano, T. Okada, H. Mizumura, R. Kunita, and H. Nishijima ALS2, a novel guanine nucleotide exchange factor for the small GTPase Rab5, is implicated in endosomal dynamics Hum Mol Genet 12 2003 1671 1687 (Pubitemid 36896660)
-
(2003)
Human Molecular Genetics
, vol.12
, Issue.14
, pp. 1671-1687
-
-
Otomo, A.1
Hadano, S.2
Okada, T.3
Mizumura, H.4
Kunita, R.5
Nishijima, H.6
Showguchi-Miyata, J.7
Yanagisawa, Y.8
Kohiki, E.9
Suga, E.10
Yasuda, M.11
Osuga, H.12
Nishimoto, T.13
Narumiya, S.14
Ikeda, J.E.15
-
181
-
-
77953266051
-
Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components
-
C.Y. Ou, V.Y. Poon, C.I. Maeder, S. Watanabe, E.K. Lehrman, and A.K. Fu Two cyclin-dependent kinase pathways are essential for polarized trafficking of presynaptic components Cell 141 2010 846 858
-
(2010)
Cell
, vol.141
, pp. 846-858
-
-
Ou, C.Y.1
Poon, V.Y.2
Maeder, C.I.3
Watanabe, S.4
Lehrman, E.K.5
Fu, A.K.6
-
182
-
-
77954132249
-
Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: From synapses toward neural networks
-
J.J. Palop, and L. Mucke Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks Nat Neurosci 13 2010 812 818
-
(2010)
Nat Neurosci
, vol.13
, pp. 812-818
-
-
Palop, J.J.1
Mucke, L.2
-
183
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
DOI 10.1038/nature05853, PII NATURE05853
-
U.B. Pandey, Z. Nie, Y. Batlevi, B.A. McCray, G.P. Ritson, and N.B. Nedelsky HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS Nature 447 2007 859 863 (Pubitemid 46920134)
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
Diprospero, N.A.8
Knight, M.A.9
Schuldiner, O.10
Padmanabhan, R.11
Hild, M.12
Berry, D.L.13
Garza, D.14
Hubbert, C.C.15
Yao, T.-P.16
Baehrecke, E.H.17
Taylor, J.P.18
-
184
-
-
77953846289
-
PARIS-htt: An optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking
-
R. Pardo, M. Molina-Calavita, G. Poizat, G. Keryer, S. Humbert, and F. Saudou pARIS-htt: an optimised expression platform to study huntingtin reveals functional domains required for vesicular trafficking Mol Brain 3 2010 17
-
(2010)
Mol Brain
, vol.3
, pp. 17
-
-
Pardo, R.1
Molina-Calavita, M.2
Poizat, G.3
Keryer, G.4
Humbert, S.5
Saudou, F.6
-
185
-
-
33749006845
-
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B)
-
DOI 10.1212/01.wnl.0000231510.89311.8b, PII 0000611420060926000037
-
N. Parkinson, P.G. Ince, M.O. Smith, R. Highley, G. Skibinski, and P.M. Andersen ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B) Neurology 67 2006 1074 1077 (Pubitemid 44454610)
-
(2006)
Neurology
, vol.67
, Issue.6
, pp. 1074-1077
-
-
Parkinson, N.1
Ince, P.G.2
Smith, M.O.3
Highley, R.4
Skibinski, G.5
Andersen, P.M.6
Morrison, K.E.7
Pall, H.S.8
Hardiman, O.9
Collinge, J.10
Shaw, P.J.11
Fisher, E.M.C.12
-
186
-
-
0023608935
-
MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties
-
B.M. Paschal, H.S. Shpetner, and R.B. Vallee MAP 1C is a microtubule-activated ATPase which translocates microtubules in vitro and has dynein-like properties J Cell Biol 105 1987 1273 1282 (Pubitemid 18029851)
-
(1987)
Journal of Cell Biology
, vol.105
, Issue.3
, pp. 1273-1282
-
-
Paschal, B.M.1
Shpetner, H.S.2
Vallee, R.B.3
-
187
-
-
0023205148
-
Retrograde transport by the microtubule-associated protein MAP 1C
-
DOI 10.1038/330181a0
-
B.M. Paschal, and R.B. Vallee Retrograde transport by the microtubule-associated protein MAP 1 C Nature 330 1987 181 183 (Pubitemid 17158550)
-
(1987)
Nature
, vol.330
, Issue.6144
, pp. 181-183
-
-
Paschal, B.M.1
Vallee, R.B.2
-
188
-
-
55549111249
-
Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport
-
D. Peretti, N. Dahan, E. Shimoni, K. Hirschberg, and S. Lev Coordinated lipid transfer between the endoplasmic reticulum and the Golgi complex requires the VAP proteins and is essential for Golgi-mediated transport Mol Biol Cell 19 2008 3871 3884
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3871-3884
-
-
Peretti, D.1
Dahan, N.2
Shimoni, E.3
Hirschberg, K.4
Lev, S.5
-
189
-
-
5444267945
-
Phenotypic analysis of neurofilament light gene mutations linked to Charcot-Marie-Tooth disease in cell culture models
-
DOI 10.1093/hmg/ddh236
-
R. Perez-Olle, S.T. Jones, and R.K. Liem Phenotypic analysis of neurofilament light gene mutations linked to Charcot-Marie-Tooth disease in cell culture models Hum Mol Genet 13 2004 2207 2220 (Pubitemid 39359921)
-
(2004)
Human Molecular Genetics
, vol.13
, Issue.19
, pp. 2207-2220
-
-
Perez-Olle, R.1
Jones, S.T.2
Liem, R.K.H.3
-
190
-
-
77950618122
-
Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans
-
E.M. Perkins, Y.L. Clarkson, N. Sabatier, D.M. Longhurst, C.P. Millward, and J. Jack Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans J Neurosci 30 2010 4857 4867
-
(2010)
J Neurosci
, vol.30
, pp. 4857-4867
-
-
Perkins, E.M.1
Clarkson, Y.L.2
Sabatier, N.3
Longhurst, D.M.4
Millward, C.P.5
Jack, J.6
-
191
-
-
68549121208
-
A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration
-
E. Perlson, G.B. Jeong, J.L. Ross, R. Dixit, K.E. Wallace, and R.G. Kalb A switch in retrograde signaling from survival to stress in rapid-onset neurodegeneration J Neurosci 29 2009 9903 9917
-
(2009)
J Neurosci
, vol.29
, pp. 9903-9917
-
-
Perlson, E.1
Jeong, G.B.2
Ross, J.L.3
Dixit, R.4
Wallace, K.E.5
Kalb, R.G.6
-
192
-
-
0025304455
-
Cytoplasmic dynein is localized to kinetochores during mitosis
-
C.M. Pfarr, M. Coue, P.M. Grissom, T.S. Hays, M.E. Porter, and J.R. McIntosh Cytoplasmic dynein is localized to kinetochores during mitosis Nature 345 1990 263 265
-
(1990)
Nature
, vol.345
, pp. 263-265
-
-
Pfarr, C.M.1
Coue, M.2
Grissom, P.M.3
Hays, T.S.4
Porter, M.E.5
McIntosh, J.R.6
-
193
-
-
27744443394
-
Cytoplasmic dynein nomenclature
-
DOI 10.1083/jcb.200508078
-
K.K. Pfister, E.M. Fisher, I.R. Gibbons, T.S. Hays, E.L. Holzbaur, and J.R. McIntosh Cytoplasmic dynein nomenclature J Cell Biol 171 2005 411 413 (Pubitemid 41586928)
-
(2005)
Journal of Cell Biology
, vol.171
, Issue.3
, pp. 411-413
-
-
Kevin Pfister, K.1
Fisher, E.M.C.2
Gibbons, I.R.3
Hays, T.S.4
Holzbaur, E.L.F.5
Richard McIntosh, J.6
Porter, M.E.7
Schroer, T.A.8
Vaughan, K.T.9
Witman, G.B.10
King, S.M.11
Vallee, R.B.12
-
194
-
-
33645778345
-
Genetic analysis of the cytoplasmic dynein subunit families
-
K.K. Pfister, P.R. Shah, H. Hummerich, A. Russ, J. Cotton, and A.A. Annuar Genetic analysis of the cytoplasmic dynein subunit families PLoS Genet 2 2006 e1
-
(2006)
PLoS Genet
, vol.2
, pp. 1
-
-
Pfister, K.K.1
Shah, P.R.2
Hummerich, H.3
Russ, A.4
Cotton, J.5
Annuar, A.A.6
-
195
-
-
65249161745
-
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta
-
G. Pigino, G. Morfini, Y. Atagi, A. Deshpande, C. Yu, and L. Jungbauer Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta Proc Natl Acad Sci U S A 106 2009 5907 5912
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5907-5912
-
-
Pigino, G.1
Morfini, G.2
Atagi, Y.3
Deshpande, A.4
Yu, C.5
Jungbauer, L.6
-
196
-
-
33646759268
-
Kinesin-1 and dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons
-
DOI 10.1091/mbc.E05-06-0526
-
A.D. Pilling, D. Horiuchi, C.M. Lively, and W.M. Saxton Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons Mol Biol Cell 17 2006 2057 2068 (Pubitemid 44011618)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.4
, pp. 2057-2068
-
-
Pilling, A.D.1
Horiuchi, D.2
Lively, C.M.3
Saxton, W.M.4
-
197
-
-
0032949365
-
Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas
-
M.E. Porter, R. Bower, J.A. Knott, P. Byrd, and W. Dentler Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in Chlamydomonas Mol Biol Cell 10 1999 693 712 (Pubitemid 29144632)
-
(1999)
Molecular Biology of the Cell
, vol.10
, Issue.3
, pp. 693-712
-
-
Porter, M.E.1
Bower, R.2
Knott, J.A.3
Byrd, P.4
Dentler, W.5
-
198
-
-
0037382240
-
Mutant dynactin in motor neuron disease
-
DOI 10.1038/ng1123
-
I. Puls, C. Jonnakuty, B.H. LaMonte, E.L. Holzbaur, M. Tokito, and E. Mann Mutant dynactin in motor neuron disease Nat Genet 33 2003 455 456 (Pubitemid 36390002)
-
(2003)
Nature Genetics
, vol.33
, Issue.4
, pp. 455-456
-
-
Puls, I.1
Jonnakuty, C.2
LaMonte, B.H.3
Holzbaur, E.L.F.4
Tokito, M.5
Mann, E.6
Floeter, M.K.7
Bidus, K.8
Drayna, D.9
Oh, S.J.10
Brown Jr., R.H.11
Ludlow, C.L.12
Fischbeck, K.H.13
-
199
-
-
20944448536
-
Distal spinal and bulbar muscular atrophy caused by dynactin mutation
-
DOI 10.1002/ana.20468
-
I. Puls, S.J. Oh, C.J. Sumner, K.E. Wallace, M.K. Floeter, and E.A. Mann Distal spinal and bulbar muscular atrophy caused by dynactin mutation Ann Neurol 57 2005 687 694 (Pubitemid 40628857)
-
(2005)
Annals of Neurology
, vol.57
, Issue.5
, pp. 687-694
-
-
Puls, I.1
Oh, S.J.2
Sumner, C.J.3
Wallace, K.E.4
Floeter, M.K.5
Mann, E.A.6
Kennedy, W.R.7
Wendelschafer-Crabb, G.8
Vortmeyer, A.9
Powers, R.10
Finnegan, K.11
Holzbaur, E.L.F.12
Fischbeck, K.H.13
Ludlow, C.L.14
-
200
-
-
63649086486
-
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
-
C. Raiborg, and H. Stenmark The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins Nature 458 2009 445 452
-
(2009)
Nature
, vol.458
, pp. 445-452
-
-
Raiborg, C.1
Stenmark, H.2
-
201
-
-
22844436451
-
Dynein mutations impair autophagic clearance of aggregate-prone proteins
-
DOI 10.1038/ng1591
-
B. Ravikumar, A. Acevedo-Arozena, S. Imarisio, Z. Berger, C. Vacher, and C.J. O'Kane Dynein mutations impair autophagic clearance of aggregate-prone proteins Nat Genet 37 2005 771 776 (Pubitemid 41754897)
-
(2005)
Nature Genetics
, vol.37
, Issue.7
, pp. 771-776
-
-
Ravikumar, B.1
Acevedo-Arozena, A.2
Imarisio, S.3
Berger, Z.4
Vacher, C.5
O'Kane, C.J.6
Brown, S.D.M.7
Rubinsztein, D.C.8
-
202
-
-
77957352699
-
The Diverse Functions of Oxysterol-Binding Proteins
-
S. Raychaudhuri, and W.A. Prinz The Diverse Functions of Oxysterol-Binding Proteins Annu Rev Cell Dev Biol 26 2010 157 177
-
(2010)
Annu Rev Cell Dev Biol
, vol.26
, pp. 157-177
-
-
Raychaudhuri, S.1
Prinz, W.A.2
-
203
-
-
33750618516
-
Microtubule Acetylation Promotes Kinesin-1 Binding and Transport
-
DOI 10.1016/j.cub.2006.09.014, PII S096098220602207X
-
N.A. Reed, D. Cai, T.L. Blasius, G.T. Jih, E. Meyhofer, and J. Gaertig Microtubule acetylation promotes kinesin-1 binding and transport Curr Biol 16 2006 2166 2172 (Pubitemid 44692098)
-
(2006)
Current Biology
, vol.16
, Issue.21
, pp. 2166-2172
-
-
Reed, N.A.1
Cai, D.2
Blasius, T.L.3
Jih, G.T.4
Meyhofer, E.5
Gaertig, J.6
Verhey, K.J.7
-
204
-
-
67650895049
-
Activity-dependent regulation of synapses by retrograde messengers
-
W.G. Regehr, M.R. Carey, and A.R. Best Activity-dependent regulation of synapses by retrograde messengers Neuron 63 2009 154 170
-
(2009)
Neuron
, vol.63
, pp. 154-170
-
-
Regehr, W.G.1
Carey, M.R.2
Best, A.R.3
-
205
-
-
77950860161
-
Retrograde signaling in axonal regeneration
-
I. Rishal, and M. Fainzilber Retrograde signaling in axonal regeneration Exp Neurol 223 2010 5 10
-
(2010)
Exp Neurol
, vol.223
, pp. 5-10
-
-
Rishal, I.1
Fainzilber, M.2
-
206
-
-
67649600680
-
Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning
-
N. Rocha, C. Kuijl, R. van der Kant, L. Janssen, D. Houben, and H. Janssen Cholesterol sensor ORP1L contacts the ER protein VAP to control Rab7-RILP-p150 Glued and late endosome positioning J Cell Biol 185 2009 1209 1225
-
(2009)
J Cell Biol
, vol.185
, pp. 1209-1225
-
-
Rocha, N.1
Kuijl, C.2
Van Der Kant, R.3
Janssen, L.4
Houben, D.5
Janssen, H.6
-
207
-
-
33744826279
-
Processive bidirectional motion of dynein-dynactin complexes in vitro
-
DOI 10.1038/ncb1421, PII N1421
-
J.L. Ross, K. Wallace, H. Shuman, Y.E. Goldman, and E.L. Holzbaur Processive bidirectional motion of dynein-dynactin complexes in vitro Nat Cell Biol 8 2006 562 570 (Pubitemid 43827348)
-
(2006)
Nature Cell Biology
, vol.8
, Issue.6
, pp. 562-570
-
-
Ross, J.L.1
Wallace, K.2
Shuman, H.3
Goldman, Y.E.4
Holzbaur, E.L.F.5
-
208
-
-
39149138988
-
Cargo transport: Molecular motors navigate a complex cytoskeleton
-
J.L. Ross, M.Y. Ali, and D.M. Warshaw Cargo transport: molecular motors navigate a complex cytoskeleton Curr Opin Cell Biol 20 2008 41 47
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 41-47
-
-
Ross, J.L.1
Ali, M.Y.2
Warshaw, D.M.3
-
209
-
-
46749144187
-
Genomic investigation of α-synuclein multiplication and parkinsonism
-
DOI 10.1002/ana.21380
-
O.A. Ross, A.T. Braithwaite, L.M. Skipper, J. Kachergus, M.M. Hulihan, and F.A. Middleton Genomic investigation of alpha-synuclein multiplication and parkinsonism Ann Neurol 63 2008 743 750 (Pubitemid 351945533)
-
(2008)
Annals of Neurology
, vol.63
, Issue.6
, pp. 743-750
-
-
Ross, O.A.1
Braithwaite, A.T.2
Skipper, L.M.3
Kachergus, J.4
Hulihan, M.M.5
Middleton, F.A.6
Nishioka, K.7
Fuchs, J.8
Gasser, T.9
Maraganore, D.M.10
Adler, C.H.11
Larvor, L.12
Chartier-Harlin, M.-C.13
Nilsson, C.14
Langston, J.W.15
Gwinn, K.16
Hattori, N.17
Farrer, M.J.18
-
210
-
-
0027519511
-
Analysis of the huntingtin gene revels a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number
-
D.C. Rubinsztein, D.E. Barton, B.C. Davison, and M.A. Ferguson-Smith Analysis of the huntingtin gene reveals a trinucleotide-length polymorphism in the region of the gene that contains two CCG-rich stretches and a correlation between decreased age of onset of Huntington's disease and CAG repeat number Hum Mol Genet 2 1993 1713 1715 (Pubitemid 23358694)
-
(1993)
Human Molecular Genetics
, vol.2
, Issue.10
, pp. 1713-1715
-
-
Rubinsztein, D.C.1
Barton, D.E.2
Davison, B.C.C.3
Ferguson-Smith, A.4
-
211
-
-
33749854516
-
Acute impairment of mitochondrial trafficking by β-amyloid peptides in hippocampal neurons
-
DOI 10.1523/JNEUROSCI.3231-06.2006
-
Y. Rui, P. Tiwari, Z. Xie, and J.Q. Zheng Acute impairment of mitochondrial trafficking by beta-amyloid peptides in hippocampal neurons J Neurosci 26 2006 10480 10487 (Pubitemid 44564598)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.41
, pp. 10480-10487
-
-
Rui, Y.1
Tiwari, P.2
Xie, Z.3
Zheng, J.Q.4
-
212
-
-
52949094629
-
Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis
-
N.J. Rutherford, Y.J. Zhang, M. Baker, J.M. Gass, N.A. Finch, and Y.F. Xu Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis PLoS Genet 4 2008 e1000193
-
(2008)
PLoS Genet
, vol.4
, pp. 1000193
-
-
Rutherford, N.J.1
Zhang, Y.J.2
Baker, M.3
Gass, J.M.4
Finch, N.A.5
Xu, Y.F.6
-
213
-
-
11144353869
-
Parkinson's disease α-synuclein mutations exhibit defective axonal transport in cultured neurons
-
DOI 10.1242/jcs.00967
-
A.R. Saha, J. Hill, M.A. Utton, A.A. Asuni, S. Ackerley, and A.J. Grierson Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons J Cell Sci 117 2004 1017 1024 (Pubitemid 38456084)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.7
, pp. 1017-1024
-
-
Saha, A.R.1
Hill, J.2
Utton, M.A.3
Asuni, A.A.4
Ackerley, S.5
Grierson, A.J.6
Miller, C.C.7
Davies, A.M.8
Buchman, V.L.9
Anderton, B.H.10
Hanger, D.P.11
-
214
-
-
36248991778
-
ESCRTing proteins in the endocytic pathway
-
DOI 10.1016/j.tibs.2007.09.010, PII S0968000407002617
-
S. Saksena, J. Sun, T. Chu, and S.D. Emr ESCRTing proteins in the endocytic pathway Trends Biochem Sci 32 2007 561 573 (Pubitemid 350123053)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.12
, pp. 561-573
-
-
Saksena, S.1
Sun, J.2
Chu, T.3
Emr, S.D.4
-
215
-
-
0029812897
-
Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis
-
S. Sasaki, and M. Iwata Impairment of fast axonal transport in the proximal axons of anterior horn neurons in amyotrophic lateral sclerosis Neurology 47 1996 535 540 (Pubitemid 26324056)
-
(1996)
Neurology
, vol.47
, Issue.2
, pp. 535-540
-
-
Sasaki, S.1
Iwata, M.2
-
216
-
-
23644437653
-
Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene
-
DOI 10.1007/s00401-005-1021-9
-
S. Sasaki, H. Warita, K. Abe, and M. Iwata Impairment of axonal transport in the axon hillock and the initial segment of anterior horn neurons in transgenic mice with a G93A mutant SOD1 gene Acta Neuropathol 110 2005 48 56 (Pubitemid 41131196)
-
(2005)
Acta Neuropathologica
, vol.110
, Issue.1
, pp. 48-56
-
-
Sasaki, S.1
Warita, H.2
Abe, K.3
Iwata, M.4
-
217
-
-
53349168419
-
Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes
-
D. Satoh, D. Sato, T. Tsuyama, M. Saito, H. Ohkura, and M.M. Rolls Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes Nat Cell Biol 10 2008 1164 1171
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1164-1171
-
-
Satoh, D.1
Sato, D.2
Tsuyama, T.3
Saito, M.4
Ohkura, H.5
Rolls, M.M.6
-
220
-
-
0024604298
-
Cytoplasmic dynein is a minus end-directed motor for membranous organelles
-
DOI 10.1016/0092-8674(89)90627-2
-
T.A. Schroer, E.R. Steuer, and M.P. Sheetz Cytoplasmic dynein is a minus end-directed motor for membranous organelles Cell 56 1989 937 946 (Pubitemid 19091006)
-
(1989)
Cell
, vol.56
, Issue.6
, pp. 937-946
-
-
Schroer, T.A.1
Steuer, E.R.2
Sheetz, M.P.3
-
221
-
-
33847784020
-
1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCδ enzymatic activities
-
DOI 10.1073/pnas.0611227104
-
Y. Serulle, G. Morfini, G. Pigino, J.E. Moreira, M. Sugimori, and S.T. Brady 1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCdelta enzymatic activities Proc Natl Acad Sci U S A 104 2007 2437 2441 (Pubitemid 46391415)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.7
, pp. 2437-2441
-
-
Serulle, Y.1
Morfini, G.2
Pigino, G.3
Moreira, J.E.4
Sugimori, M.5
Brady, S.T.6
Llinas, R.R.7
-
222
-
-
77954957020
-
Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport
-
P. Shi, A.L. Strom, J. Gal, and H. Zhu Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport Biochim Biophys Acta 1802 2010 707 716
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 707-716
-
-
Shi, P.1
Strom, A.L.2
Gal, J.3
Zhu, H.4
-
223
-
-
62449332148
-
Stimulated nuclear translocation of NF-kappaB and shuttling differentially depend on dynein and the dynactin complex
-
C.K. Shrum, D. Defrancisco, and M.K. Meffert Stimulated nuclear translocation of NF-kappaB and shuttling differentially depend on dynein and the dynactin complex Proc Natl Acad Sci U S A 106 2009 2647 2652
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2647-2652
-
-
Shrum, C.K.1
Defrancisco, D.2
Meffert, M.K.3
-
224
-
-
58749097964
-
Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration
-
C.L. Simpson, R. Lemmens, K. Miskiewicz, W.J. Broom, V.K. Hansen, and P.W. van Vught Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration Hum Mol Genet 18 2009 472 481
-
(2009)
Hum Mol Genet
, vol.18
, pp. 472-481
-
-
Simpson, C.L.1
Lemmens, R.2
Miskiewicz, K.3
Broom, W.J.4
Hansen, V.K.5
Van Vught, P.W.6
-
225
-
-
64449085303
-
Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons
-
C. Sinadinos, T. Burbidge-King, D. Soh, L.M. Thompson, J.L. Marsh, and A. Wyttenbach Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons Neurobiol Dis 34 2009 389 395
-
(2009)
Neurobiol Dis
, vol.34
, pp. 389-395
-
-
Sinadinos, C.1
Burbidge-King, T.2
Soh, D.3
Thompson, L.M.4
Marsh, J.L.5
Wyttenbach, A.6
-
226
-
-
0027212769
-
Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system
-
S.S. Sisodia, E.H. Koo, P.N. Hoffman, G. Perry, and D.L. Price Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system J Neurosci 13 1993 3136 3142 (Pubitemid 23199238)
-
(1993)
Journal of Neuroscience
, vol.13
, Issue.7
, pp. 3136-3142
-
-
Sisodia, S.S.1
Koo, E.H.2
Hoffman, P.N.3
Perry, G.4
Price, D.L.5
-
227
-
-
23044471011
-
Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia
-
DOI 10.1038/ng1609
-
G. Skibinski, N.J. Parkinson, J.M. Brown, L. Chakrabarti, S.L. Lloyd, and H. Hummerich Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia Nat Genet 37 2005 806 808 (Pubitemid 41077105)
-
(2005)
Nature Genetics
, vol.37
, Issue.8
, pp. 806-808
-
-
Skibinski, G.1
Parkinson, N.J.2
Brown, J.M.3
Chakrabarti, L.4
Lloyd, S.L.5
Hummerich, H.6
Nielsen, J.E.7
Hodges, J.R.8
Spillantini, M.G.9
Thusgaard, T.10
Brandner, S.11
Brun, A.12
Rossor, M.N.13
Gade, A.14
Johannsen, P.15
Sorensen, S.A.16
Gydesen, S.17
Fisher, E.M.C.18
Collinge, J.19
-
228
-
-
39549098329
-
Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease
-
DOI 10.1523/JNEUROSCI.3677-07.2008
-
M.R. Spinosa, C. Progida, A. De Luca, A.M. Colucci, P. Alifano, and C. Bucci Functional characterization of Rab7 mutant proteins associated with Charcot-Marie-Tooth type 2B disease J Neurosci 28 2008 1640 1648 (Pubitemid 351287044)
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.7
, pp. 1640-1648
-
-
Spinosa, M.R.1
Progida, C.2
De Luca, A.3
Colucci, A.M.R.4
Alifano, P.5
Bucci, C.6
-
229
-
-
77951753826
-
Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry
-
D. Splinter, M.E. Tanenbaum, A. Lindqvist, D. Jaarsma, A. Flotho, and K.L. Yu Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry PLoS Biol 8 2010 e1000350
-
(2010)
PLoS Biol
, vol.8
, pp. 1000350
-
-
Splinter, D.1
Tanenbaum, M.E.2
Lindqvist, A.3
Jaarsma, D.4
Flotho, A.5
Yu, K.L.6
-
230
-
-
41149180753
-
TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis
-
DOI 10.1126/science.1154584
-
J. Sreedharan, I.P. Blair, V.B. Tripathi, X. Hu, C. Vance, and B. Rogelj TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis Science 319 2008 1668 1672 (Pubitemid 351432505)
-
(2008)
Science
, vol.319
, Issue.5870
, pp. 1668-1672
-
-
Sreedharan, J.1
Blair, I.P.2
Tripathi, V.B.3
Hu, X.4
Vance, C.5
Rogelj, B.6
Ackerley, S.7
Durnall, J.C.8
Williams, K.L.9
Buratti, E.10
Baralle, F.11
De Belleroche, J.12
Mitchell, J.D.13
Leigh, P.N.14
Al-Chalabi, A.15
Miller, C.C.16
Nicholson, G.17
Shaw, C.E.18
-
231
-
-
77950526211
-
Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes
-
M.C. Stankewich, B. Gwynn, T. Ardito, L. Ji, J. Kim, and R.F. Robledo Targeted deletion of betaIII spectrin impairs synaptogenesis and generates ataxic and seizure phenotypes Proc Natl Acad Sci U S A 107 2010 6022 6027
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 6022-6027
-
-
Stankewich, M.C.1
Gwynn, B.2
Ardito, T.3
Ji, L.4
Kim, J.5
Robledo, R.F.6
-
232
-
-
54949151536
-
Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides
-
G.B. Stokin, A. Almenar-Queralt, S. Gunawardena, E.M. Rodrigues, T. Falzone, and J. Kim Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides Hum Mol Genet 17 2008 3474 3486
-
(2008)
Hum Mol Genet
, vol.17
, pp. 3474-3486
-
-
Stokin, G.B.1
Almenar-Queralt, A.2
Gunawardena, S.3
Rodrigues, E.M.4
Falzone, T.5
Kim, J.6
-
233
-
-
33746355958
-
Axonal transport and Alzheimer's disease
-
DOI 10.1146/annurev.biochem.75.103004.142637
-
G.B. Stokin, and L.S. Goldstein Axonal transport and Alzheimer's disease Annu Rev Biochem 75 2006 607 627 (Pubitemid 44118045)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 607-627
-
-
Stokin, G.B.1
Goldstein, L.S.B.2
-
234
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's diseases
-
DOI 10.1126/science.1105681
-
G.B. Stokin, C. Lillo, T.L. Falzone, R.G. Brusch, E. Rockenstein, and S.L. Mount Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease Science 307 2005 1282 1288 (Pubitemid 40299973)
-
(2005)
Science
, vol.307
, Issue.5713
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
Brusch, R.G.4
Rockenstein, E.5
Mount, S.L.6
Raman, R.7
Davies, P.8
Masliah, E.9
Williams, D.S.10
Goldstein, L.S.B.11
-
235
-
-
53049090386
-
Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation
-
A.L. Strom, P. Shi, F. Zhang, J. Gal, R. Kilty, and L.J. Hayward Interaction of amyotrophic lateral sclerosis (ALS)-related mutant copper-zinc superoxide dismutase with the dynein-dynactin complex contributes to inclusion formation J Biol Chem 283 2008 22795 22805
-
(2008)
J Biol Chem
, vol.283
, pp. 22795-22805
-
-
Strom, A.L.1
Shi, P.2
Zhang, F.3
Gal, J.4
Kilty, R.5
Hayward, L.J.6
-
236
-
-
67349135343
-
ESCRT proteins in physiology and disease
-
S. Stuffers, A. Brech, and H. Stenmark ESCRT proteins in physiology and disease Exp Cell Res 315 2009 1619 1626
-
(2009)
Exp Cell Res
, vol.315
, pp. 1619-1626
-
-
Stuffers, S.1
Brech, A.2
Stenmark, H.3
-
237
-
-
10744224530
-
Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport
-
DOI 10.1016/S0896-6273(03)00569-5
-
G. Szebenyi, G.A. Morfini, A. Babcock, M. Gould, K. Selkoe, and D.L. Stenoien Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport Neuron 40 2003 41 52 (Pubitemid 37229083)
-
(2003)
Neuron
, vol.40
, Issue.1
, pp. 41-52
-
-
Szebenyi, G.1
Morfini, G.A.2
Babcock, A.3
Gould, M.4
Selkoe, K.5
Stenoien, D.L.6
Young, M.7
Faber, P.W.8
MacDonald, M.E.9
McPhaul, M.J.10
Brady, S.T.11
-
239
-
-
67049171648
-
Neuronal protein trafficking associated with Alzheimer disease: From APP and BACE1 to glutamate receptors
-
B.L. Tang Neuronal protein trafficking associated with Alzheimer disease: from APP and BACE1 to glutamate receptors Cell Adhes Migr 3 2009 118 128
-
(2009)
Cell Adhes Migr
, vol.3
, pp. 118-128
-
-
Tang, B.L.1
-
240
-
-
0025329534
-
Recent progress on structural interactions of the endoplasmic reticulum
-
M. Terasaki Recent progress on structural interactions of the endoplasmic reticulum Cell Motil Cytoskeleton 15 1990 71 75 (Pubitemid 20132387)
-
(1990)
Cell Motility and the Cytoskeleton
, vol.15
, Issue.2
, pp. 71-75
-
-
Terasaki, M.1
-
241
-
-
50849110466
-
A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice
-
E. Teuling, V. van Dis, P.S. Wulf, E.D. Haasdijk, A. Akhmanova, and C.C. Hoogenraad A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice Hum Mol Genet 17 2008 2849 2862
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2849-2862
-
-
Teuling, E.1
Van Dis, V.2
Wulf, P.S.3
Haasdijk, E.D.4
Akhmanova, A.5
Hoogenraad, C.C.6
-
242
-
-
77952900626
-
Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs
-
N. Thayanidhi, J.R. Helm, D.C. Nycz, M. Bentley, Y. Liang, and J.C. Hay Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs Mol Biol Cell 21 2010 1850 1863
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1850-1863
-
-
Thayanidhi, N.1
Helm, J.R.2
Nycz, D.C.3
Bentley, M.4
Liang, Y.5
Hay, J.C.6
-
243
-
-
70350156915
-
Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort
-
N. Ticozzi, V. Silani, A.L. Leclerc, P. Keagle, C. Gellera, and A. Ratti Analysis of FUS gene mutation in familial amyotrophic lateral sclerosis within an Italian cohort Neurology 73 15 2009 1180 1185
-
(2009)
Neurology
, vol.73
, Issue.15
, pp. 1180-1185
-
-
Ticozzi, N.1
Silani, V.2
Leclerc, A.L.3
Keagle, P.4
Gellera, C.5
Ratti, A.6
-
244
-
-
2642536202
-
Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor
-
DOI 10.1074/jbc.M313504200
-
J.D. Topp, N.W. Gray, R.D. Gerard, and B.F. Horazdovsky Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor J Biol Chem 279 2004 24612 24623 (Pubitemid 38725328)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.23
, pp. 24612-24623
-
-
Topp, J.D.1
Gray, N.W.2
Gerard, R.D.3
Horazdovsky, B.F.4
-
245
-
-
4444316194
-
Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro
-
DOI 10.1128/MCB.24.18.8195-8209.2004
-
E. Trushina, R.B. Dyer, J.D. Badger 2nd, D. Ure, L. Eide, and D.D. Tran Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro Mol Cell Biol 24 2004 8195 8209 (Pubitemid 39167467)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.18
, pp. 8195-8209
-
-
Trushina, E.1
Dyer, R.B.2
Badger II, J.D.3
Ure, D.4
Eide, L.5
Tran, D.D.6
Vrieze, B.T.7
Legendre-Guillemin, V.8
McPherson, P.S.9
Mandavilli, B.S.10
Van Houten, B.11
Zeitlin, S.12
McNiven, M.13
Aebersold, R.14
Hayden, M.15
Parisi, J.E.16
Seeberg, E.17
Dragatsis, I.18
Doyle, K.19
Bender, A.20
Chacko, C.21
McMurray, C.T.22
more..
-
246
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
DOI 10.1038/sj.emboj.7601963, PII 7601963
-
G. Twig, A. Elorza, A.J. Molina, H. Mohamed, J.D. Wikstrom, and G. Walzer Fission and selective fusion govern mitochondrial segregation and elimination by autophagy EMBO J 27 2008 433 446 (Pubitemid 351161653)
-
(2008)
EMBO Journal
, vol.27
, Issue.2
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.A.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
247
-
-
77953583994
-
Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations
-
H. Urwin, A. Authier, J.E. Nielsen, D. Metcalf, C. Powell, and K. Froud Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations Hum Mol Genet 19 2010 2228 2238
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2228-2238
-
-
Urwin, H.1
Authier, A.2
Nielsen, J.E.3
Metcalf, D.4
Powell, C.5
Froud, K.6
-
248
-
-
37849023471
-
CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro
-
J. van der Zee, H. Urwin, S. Engelborghs, M. Bruyland, R. Vandenberghe, and B. Dermaut CHMP2B C-truncating mutations in frontotemporal lobar degeneration are associated with an aberrant endosomal phenotype in vitro Hum Mol Genet 17 2008 313 322
-
(2008)
Hum Mol Genet
, vol.17
, pp. 313-322
-
-
Van Der Zee, J.1
Urwin, H.2
Engelborghs, S.3
Bruyland, M.4
Vandenberghe, R.5
Dermaut, B.6
-
249
-
-
77954891060
-
Synapse pathology in psychiatric and neurologic disease
-
M. van Spronsen, and C.C. Hoogenraad Synapse pathology in psychiatric and neurologic disease Curr Neurol Neurosci Rep 10 2010 207 214
-
(2010)
Curr Neurol Neurosci Rep
, vol.10
, pp. 207-214
-
-
Van Spronsen, M.1
Hoogenraad, C.C.2
-
250
-
-
20544456820
-
Microtubule plus ends, motors, and traffic of Golgi membranes
-
DOI 10.1016/j.bbamcr.2005.05.001, PII S0167488905000832
-
K.T. Vaughan Microtubule plus ends, motors, and traffic of Golgi membranes Biochim Biophys Acta 1744 2005 316 324 (Pubitemid 40848250)
-
(2005)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1744
, Issue.3 SPEC. ISS.
, pp. 316-324
-
-
Vaughan, K.T.1
-
251
-
-
0029563632
-
Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued
-
K.T. Vaughan, and R.B. Vallee Cytoplasmic dynein binds dynactin through a direct interaction between the intermediate chains and p150Glued J Cell Biol 131 1995 1507 1516
-
(1995)
J Cell Biol
, vol.131
, pp. 1507-1516
-
-
Vaughan, K.T.1
Vallee, R.B.2
-
252
-
-
77957287735
-
Axonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type i Charcot-Marie-Tooth neuropathy
-
N. Vavlitou, I. Sargiannidou, K. Markoullis, K. Kyriacou, S.S. Scherer, and K.A. Kleopa Axonal pathology precedes demyelination in a mouse model of X-linked demyelinating/type I Charcot-Marie-Tooth neuropathy J Neuropathol Exp Neurol 69 2010 945 958
-
(2010)
J Neuropathol Exp Neurol
, vol.69
, pp. 945-958
-
-
Vavlitou, N.1
Sargiannidou, I.2
Markoullis, K.3
Kyriacou, K.4
Scherer, S.S.5
Kleopa, K.A.6
-
253
-
-
0037371509
-
Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy
-
DOI 10.1086/367847
-
K. Verhoeven, P. De Jonghe, K. Coen, N. Verpoorten, M. Auer-Grumbach, and J.M. Kwon Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy Am J Hum Genet 72 2003 722 727 (Pubitemid 36255971)
-
(2003)
American Journal of Human Genetics
, vol.72
, Issue.3
, pp. 722-727
-
-
Verhoeven, K.1
De Jonghe, P.2
Coen, K.3
Verpoorten, N.4
Auer-Grumbach, M.5
Kwon, J.M.6
FitzPatrick, D.7
Schmedding, E.8
De Vriendt, E.9
Jacobs, A.10
Van Gerwen, V.11
Wagner, K.12
Hartung, H.-P.13
Timmerman, V.14
-
254
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
C. Vives-Bauza, C. Zhou, Y. Huang, M. Cui, R.L. de Vries, and J. Kim PINK1-dependent recruitment of Parkin to mitochondria in mitophagy Proc Natl Acad Sci U S A 107 1 2010 378 383
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, Issue.1
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
-
255
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
C. Vives-Bauza, C. Zhou, Y. Huang, M. Cui, R.L. de Vries, and J. Kim PINK1-dependent recruitment of Parkin to mitochondria in mitophagy Proc Natl Acad Sci U S A 107 2010 378 383
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
-
256
-
-
77957737750
-
Tau Reduction Prevents A{beta}-Induced Defects in Axonal Transport
-
K.A. Vossel, K. Zhang, J. Brodbeck, A.C. Daub, P. Sharma, and S. Finkbeiner Tau Reduction Prevents A{beta}-Induced Defects in Axonal Transport Science 330 6001 2010 198
-
(2010)
Science
, vol.330
, Issue.6001
, pp. 198
-
-
Vossel, K.A.1
Zhang, K.2
Brodbeck, J.3
Daub, A.C.4
Sharma, P.5
Finkbeiner, S.6
-
257
-
-
6344272746
-
The interaction of neurofilaments with the microtubule motor cytoplasmic dynein
-
DOI 10.1091/mbc.E04-05-0401
-
O.I. Wagner, J. Ascano, M. Tokito, J.F. Leterrier, P.A. Janmey, and E.L. Holzbaur The interaction of neurofilaments with the microtubule motor cytoplasmic dynein Mol Biol Cell 15 2004 5092 5100 (Pubitemid 39392222)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.11
, pp. 5092-5100
-
-
Wagner, O.I.1
Ascano, J.2
Tokito, M.3
Leterrier, J.-F.4
Janmey, P.A.5
Holzbaur, E.L.F.6
-
258
-
-
33846225133
-
Huntington's disease
-
DOI 10.1016/S0140-6736(07)60111-1, PII S0140673607601111
-
F.O. Walker Huntington's disease Lancet 369 2007 218 228 (Pubitemid 46107685)
-
(2007)
Lancet
, vol.369
, Issue.9557
, pp. 218-228
-
-
Walker, F.O.1
-
259
-
-
33750437278
-
Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1α in Huntington's disease neurodegeneration
-
DOI 10.1016/j.cmet.2006.10.004, PII S1550413106003329
-
P. Weydt, V.V. Pineda, A.E. Torrence, R.T. Libby, T.F. Satterfield, and E.R. Lazarowski Thermoregulatory and metabolic defects in Huntington's disease transgenic mice implicate PGC-1alpha in Huntington's disease neurodegeneration Cell Metab 4 2006 349 362 (Pubitemid 44645069)
-
(2006)
Cell Metabolism
, vol.4
, Issue.5
, pp. 349-362
-
-
Weydt, P.1
Pineda, V.V.2
Torrence, A.E.3
Libby, R.T.4
Satterfield, T.F.5
Lazarowski, EduardoR.6
Gilbert, M.L.7
Morton, G.J.8
Bammler, T.K.9
Strand, A.D.10
Cui, L.11
Beyer, R.P.12
Easley, C.N.13
Smith, A.C.14
Krainc, D.15
Luquet, S.16
Sweet, IanR.17
Schwartz, M.W.18
La Spada, A.R.19
-
260
-
-
68949150785
-
What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy?
-
J.D. Wikstrom, G. Twig, and O.S. Shirihai What can mitochondrial heterogeneity tell us about mitochondrial dynamics and autophagy? Int J Biochem Cell Biol 41 2009 1914 1927
-
(2009)
Int J Biochem Cell Biol
, vol.41
, pp. 1914-1927
-
-
Wikstrom, J.D.1
Twig, G.2
Shirihai, O.S.3
-
261
-
-
0033366384
-
Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
-
DOI 10.1038/4553
-
T.L. Williamson, and D.W. Cleveland Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons Nat Neurosci 2 1999 50 56 (Pubitemid 30488940)
-
(1999)
Nature Neuroscience
, vol.2
, Issue.1
, pp. 50-56
-
-
Williamson, T.L.1
Cleveland, D.W.2
-
262
-
-
77957189194
-
Alpha-Synuclein impairs macroautophagy: Implications for Parkinson's disease
-
A.R. Winslow, C.W. Chen, S. Corrochano, A. Acevedo-Arozena, D.E. Gordon, and A.A. Peden alpha-Synuclein impairs macroautophagy: implications for Parkinson's disease J Cell Biol 190 2010 1023 1037
-
(2010)
J Cell Biol
, vol.190
, pp. 1023-1037
-
-
Winslow, A.R.1
Chen, C.W.2
Corrochano, S.3
Acevedo-Arozena, A.4
Gordon, D.E.5
Peden, A.A.6
-
263
-
-
77954116814
-
Autophagy gone awry in neurodegenerative diseases
-
E. Wong, and A.M. Cuervo Autophagy gone awry in neurodegenerative diseases Nat Neurosci 13 2010 805 811
-
(2010)
Nat Neurosci
, vol.13
, pp. 805-811
-
-
Wong, E.1
Cuervo, A.M.2
-
264
-
-
0034785509
-
The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis
-
DOI 10.1038/ng1001-160
-
Y. Yang, A. Hentati, H.X. Deng, O. Dabbagh, T. Sasaki, and M. Hirano The gene encoding alsin, a protein with three guanine-nucleotide exchange factor domains, is mutated in a form of recessive amyotrophic lateral sclerosis Nat Genet 29 2001 160 165 (Pubitemid 32952652)
-
(2001)
Nature Genetics
, vol.29
, Issue.2
, pp. 160-165
-
-
Yang, Y.1
Hentati, A.2
Deng, H.-X.3
Dabbagh, O.4
Sasaki, T.5
Hirano, M.6
Hung, W.-Y.7
Ouahchi, K.8
Yan, J.9
Azim, A.C.10
Cole, N.11
Gascon, G.12
Yagmour, A.13
Ben-Hamida, M.14
Pericak-Vance, M.15
Hentati, F.16
Siddique, T.17
-
265
-
-
42949094584
-
TDP-43 mutation in familial amyotrophic lateral sclerosis
-
DOI 10.1002/ana.21392
-
A. Yokoseki, A. Shiga, C.F. Tan, A. Tagawa, H. Kaneko, and A. Koyama TDP-43 mutation in familial amyotrophic lateral sclerosis Ann Neurol 63 2008 538 542 (Pubitemid 351614721)
-
(2008)
Annals of Neurology
, vol.63
, Issue.4
, pp. 538-542
-
-
Yokoseki, A.1
Shiga, A.2
Tan, C.-F.3
Tagawa, A.4
Kaneko, H.5
Koyama, A.6
Eguchi, H.7
Tsujino, A.8
Ikeuchi, T.9
Kakita, A.10
Okamoto, K.11
Nishizawa, M.12
Takahashi, H.13
Onodera, O.14
-
266
-
-
0026507671
-
Distribution of cytoplasmic and axonemal dyneins in rat tissues
-
T. Yoshida, H. Takanari, and K. Izutsu Distribution of cytoplasmic and axonemal dyneins in rat tissues J Cell Sci 101 Pt 3 1992 579 587
-
(1992)
J Cell Sci
, vol.101
, Issue.PART 3
, pp. 579-587
-
-
Yoshida, T.1
Takanari, H.2
Izutsu, K.3
-
267
-
-
47749146105
-
Localized Regulation of Axonal RanGTPase Controls Retrograde Injury Signaling in Peripheral Nerve
-
DOI 10.1016/j.neuron.2008.05.029, PII S0896627308004923
-
D. Yudin, S. Hanz, S. Yoo, E. Iavnilovitch, D. Willis, and T. Gradus Localized regulation of axonal RanGTPase controls retrograde injury signaling in peripheral nerve Neuron 59 2008 241 252 (Pubitemid 352033684)
-
(2008)
Neuron
, vol.59
, Issue.2
, pp. 241-252
-
-
Yudin, D.1
Hanz, S.2
Yoo, S.3
Iavnilovitch, E.4
Willis, D.5
Gradus, T.6
Vuppalanchi, D.7
Segal-Ruder, Y.8
Ben-Yaakov, K.9
Hieda, M.10
Yoneda, Y.11
Twiss, J.L.12
Fainzilber, M.13
-
268
-
-
57049184027
-
Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons
-
DOI 10.1093/hmg/ddn281
-
D. Zala, E. Colin, H. Rangone, G. Liot, S. Humbert, and F. Saudou Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons Hum Mol Genet 17 2008 3837 3846 (Pubitemid 352762847)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.24
, pp. 3837-3846
-
-
Zala, D.1
Colin, E.2
Rangone, H.3
Liot, G.4
Humbert, S.5
Saudou, F.6
-
269
-
-
0030817291
-
Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
-
DOI 10.1083/jcb.139.5.1307
-
B. Zhang, P. Tu, F. Abtahian, J.Q. Trojanowski, and V.M. Lee Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation J Cell Biol 139 1997 1307 1315 (Pubitemid 27523216)
-
(1997)
Journal of Cell Biology
, vol.139
, Issue.5
, pp. 1307-1315
-
-
Zhang, B.1
Tu, P.-H.2
Abtahian, F.3
Trojanowski, J.Q.4
Lee, V.M.-Y.5
-
270
-
-
34447550238
-
Interaction between familial Amyotrophic Lateral Sclerosis (ALS)-linked SOD1 mutants and the dynein complex
-
DOI 10.1074/jbc.M609743200
-
F. Zhang, A.L. Strom, K. Fukada, S. Lee, L.J. Hayward, and H. Zhu Interaction between familial amyotrophic lateral sclerosis (ALS)-linked SOD1 mutants and the dynein complex J Biol Chem 282 2007 16691 16699 (Pubitemid 47100405)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.22
, pp. 16691-16699
-
-
Zhang, F.1
Strom, A.-L.2
Fukada, K.3
Lee, S.4
Hayward, L.J.5
Zhu, H.6
-
271
-
-
70350211470
-
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice
-
X. Zhang, K. Lei, X. Yuan, X. Wu, Y. Zhuang, and T. Xu SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice Neuron 64 2009 173 187
-
(2009)
Neuron
, vol.64
, pp. 173-187
-
-
Zhang, X.1
Lei, K.2
Yuan, X.3
Wu, X.4
Zhuang, Y.5
Xu, T.6
-
272
-
-
53349164540
-
Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons
-
Y. Zheng, J. Wildonger, B. Ye, Y. Zhang, A. Kita, and S.H. Younger Dynein is required for polarized dendritic transport and uniform microtubule orientation in axons Nat Cell Biol 10 2008 1172 1180
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1172-1180
-
-
Zheng, Y.1
Wildonger, J.2
Ye, B.3
Zhang, Y.4
Kita, A.5
Younger, S.H.6
-
273
-
-
67049158203
-
Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy
-
X. Zhou, T. Ikenoue, X. Chen, L. Li, K. Inoki, and K.L. Guan Rheb controls misfolded protein metabolism by inhibiting aggresome formation and autophagy Proc Natl Acad Sci U S A 106 2009 8923 8928
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 8923-8928
-
-
Zhou, X.1
Ikenoue, T.2
Chen, X.3
Li, L.4
Inoki, K.5
Guan, K.L.6
-
274
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
DOI 10.1126/science.1059581
-
C. Zuccato, A. Ciammola, D. Rigamonti, B.R. Leavitt, D. Goffredo, and L. Conti Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease Science 293 2001 493 498 (Pubitemid 32679077)
-
(2001)
Science
, vol.293
, Issue.5529
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
-
275
-
-
23044515099
-
Functions and mechanisms of retrograde neurotrophin signalling
-
DOI 10.1038/nrn1727
-
L.S. Zweifel, R. Kuruvilla, and D.D. Ginty Functions and mechanisms of retrograde neurotrophin signalling Nat Rev Neurosci 6 2005 615 625 (Pubitemid 41059336)
-
(2005)
Nature Reviews Neuroscience
, vol.6
, Issue.8
, pp. 615-625
-
-
Zweifel, L.S.1
Kuruvilla, R.2
Ginty, D.D.3
|