Gene targeting of GAN in mouse causes a toxic accumulation of microtubule-associated protein 8 and impaired retrograde axonal transport

Human Molecular Genetics

Volumn 15, Issue 9, 2006, Pages 1451-1463

  Ding, Jianqing ^a   Allen, Elizabeth ^a   Wang, Wei ^a   Valle, Angela ^a   Wu, Chengbiao ^a   Nardine, Timothy ^a   Cui, Bianxiao ^b   Yi, Jing ^c   Taylor, Anne ^d   Jeon, Noo Li ^d   Chu, Steven ^b   So, Yuen ^a   Vogel, Hannes ^a   Tolwani, Ravi ^a   Mobley, William ^a   Yang, Yanmin ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d University of California at Irvine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYNEIN ADENOSINE TRIPHOSPHATASE; MICROTUBULE ASSOCIATED PROTEIN; PROTEASOME; UBIQUITIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; GENE DISRUPTION; GENE TARGETING; GIANT AXONAL NEUROPATHY; IN VITRO STUDY; MICROTUBULE; MOUSE; NEUROLOGY; NEUROPATHY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RETROGRADE NERVE FIBER TRANSPORT; WILD TYPE;

ANIMALS; AXONAL TRANSPORT; AXONS; BRAIN CHEMISTRY; CELL DEATH; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DISEASE MODELS, ANIMAL; DYNEIN ATPASE; GANGLIA, SPINAL; GENE TARGETING; HUMANS; MICE; MICE, KNOCKOUT; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; SCIATIC NERVE;

ANIMALIA;

EID: 33646140347     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl069     Document Type: Article

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