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Volumn 16, Issue 6, 2005, Pages 533-536

Mutant superoxide dismutase disrupts cytoplasmic dynein in motor neurons

Author keywords

Amyotrophic lateral sclerosis; Axonal transport; Cu Zn superoxide dismutase I; Cytoplasmic dynein; Dynactin; Retrograde transport

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; MUTANT PROTEIN; SUPEROXIDE DISMUTASE;

EID: 17844399774     PISSN: 09594965     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001756-200504250-00002     Document Type: Article
Times cited : (116)

References (24)
  • 1
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: Deciphering selective motor neuron death in ALS
    • Cleveland DW, Rothstein JD. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2001; 2:806-819.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 2
    • 0033004145 scopus 로고    scopus 로고
    • Cytoplasmic dynein and dynactin in cell division and intracellular transport
    • Karki S, Holzbaur ELF. Cytoplasmic dynein and dynactin in cell division and intracellular transport. Curr Opin Cell Biol 1999; 11:45-53.
    • (1999) Curr Opin Cell Biol , vol.11 , pp. 45-53
    • Karki, S.1    Holzbaur, E.L.F.2
  • 3
    • 2342561865 scopus 로고    scopus 로고
    • Motor neurons rely on motor proteins
    • Holzbaur ELF. Motor neurons rely on motor proteins. Trends Cell Biol 2004; 14:233-240.
    • (2004) Trends Cell Biol , vol.14 , pp. 233-240
    • Holzbaur, E.L.F.1
  • 5
    • 0037734370 scopus 로고    scopus 로고
    • Mutations in dynein link motor neuron degeneration to defects in retrograde transport
    • Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S et al. Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science 2003; 300:808-812.
    • (2003) Science , vol.300 , pp. 808-812
    • Hafezparast, M.1    Klocke, R.2    Ruhrberg, C.3    Marquardt, A.4    Ahmad-Annuar, A.5    Bowen, S.6
  • 6
    • 0037198698 scopus 로고    scopus 로고
    • Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration
    • LaMonte BH, Holloway BA, Tokito M, Van Winkle T, Howland DS, Holzbaur ELF. Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration. Neuron 2002; 34:715-727.
    • (2002) Neuron , vol.34 , pp. 715-727
    • LaMonte, B.H.1    Holloway, B.A.2    Tokito, M.3    Van Winkle, T.4    Howland, D.S.5    Holzbaur, E.L.F.6
  • 7
    • 0028284779 scopus 로고
    • Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation
    • Gurney ME, Pu H, Chiu AY, Dal Canto MC, Polchow CY, Alexander DD et al. Motor neuron degeneration in mice that express a human Cu, Zn superoxide dismutase mutation. Science 1994; 264:1772-1775.
    • (1994) Science , vol.264 , pp. 1772-1775
    • Gurney, M.E.1    Pu, H.2    Chiu, A.Y.3    Dal Canto, M.C.4    Polchow, C.Y.5    Alexander, D.D.6
  • 8
    • 0031938716 scopus 로고    scopus 로고
    • Differential effects of neurotrophic factors on motoneuron retrograde labeling in a murine model of motoneuron disease
    • Sagot Y, Rosse T, Vejsada R, Perrelet D, Kato AC. Differential effects of neurotrophic factors on motoneuron retrograde labeling in a murine model of motoneuron disease. J Neurosci 1998; 18:1132-1141.
    • (1998) J Neurosci , vol.18 , pp. 1132-1141
    • Sagot, Y.1    Rosse, T.2    Vejsada, R.3    Perrelet, D.4    Kato, A.C.5
  • 9
    • 0029742626 scopus 로고    scopus 로고
    • Functionally distinct isoforms of dynactin are expressed in human neurons
    • Tokito MK, Howland DS, Lee VM-Y, Holzbaur ELF. Functionally distinct isoforms of dynactin are expressed in human neurons. Mol Biol Cell 1996; 7:1167-1180.
    • (1996) Mol Biol Cell , vol.7 , pp. 1167-1180
    • Tokito, M.K.1    Howland, D.S.2    Lee, V.M.-Y.3    Holzbaur, E.L.F.4
  • 10
    • 0037347393 scopus 로고    scopus 로고
    • BDNF heightens the sensitivity of motor neurons to excitotoxic insults through activation of TrkB
    • Hu P, Kalb RG. BDNF heightens the sensitivity of motor neurons to excitotoxic insults through activation of TrkB. J Neurochemistry 2003; 84:1421-1430.
    • (2003) J Neurochemistry , vol.84 , pp. 1421-1430
    • Hu, P.1    Kalb, R.G.2
  • 11
    • 0031007040 scopus 로고    scopus 로고
    • Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus
    • Neve RL, Howe JR, Hong S, Kalb RG. Introduction of the glutamate receptor subunit 1 into motor neurons in vitro and in vivo using a recombinant herpes simplex virus. Neuroscience 1997; 79:435-447.
    • (1997) Neuroscience , vol.79 , pp. 435-447
    • Neve, R.L.1    Howe, J.R.2    Hong, S.3    Kalb, R.G.4
  • 12
    • 0032720268 scopus 로고    scopus 로고
    • Influence of age on regeneration in the peripheral nervous system
    • Kerezoudi E, Thomas PK. Influence of age on regeneration in the peripheral nervous system. Gerontology 1999; 45:301-306.
    • (1999) Gerontology , vol.45 , pp. 301-306
    • Kerezoudi, E.1    Thomas, P.K.2
  • 14
    • 0029966363 scopus 로고    scopus 로고
    • Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions
    • Tu PH, Raju P, Robinson KA, Gurney ME, Trojanowski JQ, Lee VM. Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions. Proc Natl Acad Sci USA 1996; 93:3155-3160.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3155-3160
    • Tu, P.H.1    Raju, P.2    Robinson, K.A.3    Gurney, M.E.4    Trojanowski, J.Q.5    Lee, V.M.6
  • 16
    • 0037198709 scopus 로고    scopus 로고
    • Dynactin is necessary for synapse stabilization
    • Eaton BA, Fetter RD, Davis GW. Dynactin is necessary for synapse stabilization. Neuron 2002; 34:729-741.
    • (2002) Neuron , vol.34 , pp. 729-741
    • Eaton, B.A.1    Fetter, R.D.2    Davis, G.W.3
  • 18
    • 0030817291 scopus 로고    scopus 로고
    • Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation
    • Zhang B, Tu P, Abtahian F, Trojanowski JQ, Lee VMY. Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation. J Cell Biol 1997; 139:1307-1315.
    • (1997) J Cell Biol , vol.139 , pp. 1307-1315
    • Zhang, B.1    Tu, P.2    Abtahian, F.3    Trojanowski, J.Q.4    Lee, V.M.Y.5
  • 19
    • 0033366384 scopus 로고    scopus 로고
    • Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons
    • Williamson TL, Cleveland DW. Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons. Nat Neuro 1999; 2:50-56.
    • (1999) Nat Neuro , vol.2 , pp. 50-56
    • Williamson, T.L.1    Cleveland, D.W.2
  • 20
    • 1642528556 scopus 로고    scopus 로고
    • Disruption of the structure of the Golgi apparatus and the function of the secretory pathway by mutants G93A and G85R of Cu, Zn superoxide dismutase (SOD1) of familial amyotrophic lateral sclerosis
    • Stieber A, Gonatas JO, Moore JS, Bantly A, Yim HS, Yim MB et al. Disruption of the structure of the Golgi apparatus and the function of the secretory pathway by mutants G93A and G85R of Cu, Zn superoxide dismutase (SOD1) of familial amyotrophic lateral sclerosis. J Neurol Sci 2004; 219:45-53.
    • (2004) J Neurol Sci , vol.219 , pp. 45-53
    • Stieber, A.1    Gonatas, J.O.2    Moore, J.S.3    Bantly, A.4    Yim, H.S.5    Yim, M.B.6
  • 21
    • 0029890685 scopus 로고    scopus 로고
    • The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease
    • Mourelatos Z, Gonatas NK, Stieber A, Gurney ME, Dal Canto MC. The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease. Proc Natl Acad Sci USA 1996; 93:5472-5477.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 5472-5477
    • Mourelatos, Z.1    Gonatas, N.K.2    Stieber, A.3    Gurney, M.E.4    Dal Canto, M.C.5
  • 22
    • 0025330692 scopus 로고
    • Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis revealed by organelle-specific antibodies
    • Mourelatos Z, Adler H, Hirona A, Donnenfeld H, Gonatos JO, Gonatos NK. Fragmentation of the Golgi apparatus of motor neurons in amyotrophic lateral sclerosis revealed by organelle-specific antibodies. Proc Natl Acad Sci USA 1990; 87:4393-4395.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4393-4395
    • Mourelatos, Z.1    Adler, H.2    Hirona, A.3    Donnenfeld, H.4    Gonatos, J.O.5    Gonatos, N.K.6
  • 23
    • 0346020435 scopus 로고    scopus 로고
    • The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
    • Kawaguchi Y, Kovacs JJ, McLaurin A, Vance JM, Ito A, Yao T-P. The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress. Cell 2003; 115:727-738.
    • (2003) Cell , vol.115 , pp. 727-738
    • Kawaguchi, Y.1    Kovacs, J.J.2    McLaurin, A.3    Vance, J.M.4    Ito, A.5    Yao, T.-P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.