Dynactin

Annual Review of Cell and Developmental Biology

Volumn 20, Issue , 2004, Pages 759-779

  Schroer, Trina A ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Centrosome; Dynein; Microtubule; Motility; Motor

Indexed keywords

ACTIN; ACTIN RELATED PROTEIN; ACTIN RELATED PROTEIN 11; DYNACTIN; DYNEIN ADENOSINE TRIPHOSPHATASE; PROTEIN; PROTEIN CAPZ; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

CELL ACTIVITY; CELL MEMBRANE; CELL NUCLEUS; CELL STRUCTURE; CELLULAR DISTRIBUTION; CYTOPLASM; EUKARYOTE; HUMAN; MICROTUBULE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW;

ANIMALS; INTRACELLULAR SPACE; MICROTUBULE-ASSOCIATED PROTEINS; PROTEIN SUBUNITS;

EUKARYOTA;

EID: 4444249640     PISSN: 10810706     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.cellbio.20.012103.094623     Document Type: Review

References (125)

1. Askham JM, Vaughan KT, Goodson HV, Morrison EE. 2002. Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome. Mol. Biol. Cell 13:3627-45
2. Beaudouin J, Gerlich D, Daigle N, Eils R, Ellenberg J. 2002. Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina. Cell 108:83-96
3. Berrueta L, Tirnauer JS, Schuyler SC, Pellman D, Bierer BE. 1999. The APC-associated protein EB1 associates with components of the dynactin complex and cytoplasmic dynein intermediate chain. Curr. Biol. 9:425-28
4. Bingham JB, King SJ, Schroer TA. 1998. Purification of dynein and dynactin from brain tissue. Methods Enzymol. 298:171-84
5. Bingham JB, Schroer TA. 1999. Self-regulated polymerization of the actin-related protein, Arp1. Curr. Biol. 9:223-26
6. Blangy A, Arnaud L, Nigg EA. 1997. Phosphorylation by p34cdc2 protein kinase regulates binding of the kinesin-related motor HsEg5 to the dynactin subunit p150. J. Biol. Chem. 272:19418-24
7. Bradley P, Cowen L, Menke M, King J, Berger B. 2001. BETAWRAP: successful prediction of parallel beta-helices from primary sequence reveals an association with many microbial pathogens. Proc. Natl. Acad. Sci. USA 98:14819-24
8. Brandon NJ, Handford EJ, Schurov I, Rain JC, Pelling M, et al. 2004. Disrupted in Schizophrenia 1 and Nude1 form a neurodevelopmentally regulated protein complex: implications for schizophrenia and other major neurological disorders. Mol. Cell. Neurosci. 25:42-55
9. Bu W, Su LK. 2003. Characterization of functional domains of human EB1 family proteins. J. Biol. Chem. 278:49721-31
10. Burkhardt JK, Echeverri CJ, Nilsson T, Vallee RB. 1997. Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintanance of membrane organelle distribution. J. Cell Biol. 139:469-84
11. Busson S, Dujardin D, Moreau A, Dompierre J, De Mey JR. 1998. Dynein and dynactin are localized to astral microtubules and at cortical sites in mitotic epithelial cells. Curr. Biol. 8:541-44
12. Cantalupo G, Alifano P, Roberti V, Bruni CB, Bucci C. 2001. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. EMBO J. 20:683-93
13. Clark SW, Meyer DI. 1992. Centractin is an actin homologue associated with the centrosome. Nature 359:246-50
14. Corcoran LJ, Mitchison TJ, Liu Q. 2004. A novel action of histone deacetylase inhibitors in a protein aggresome disease model. Curr. Biol. 12:488-92
15. De Brabander M, Nuydens R, Geerts H, Hopkins CR. 1988. Dynamic behavior of the transferrin receptor followed in living epidermoid carcinoma (A431) cells with nanovid microscopy. Cell Motil. Cytoskelet. 9:30-47
16. Deacon SW, Serpinskaya AS, Vaughan PS, Lopez Fanarraga M, Vernos I, et al. 2003. Dynactin is required for bidirectional organelle transport. J. Cell Biol. 160:297-301
17. Dohner K, Wolfstein A, Prank U, Echeverri C, Dujardin D, et al. 2002. Function of dynein and dynactin in herpes simplex virus capsid transport. Mol. Biol. Cell 13:2795-809
18. Dujardin DL, Barnhart LE, Stehman SA, Gomes ER, Gundersen GG, et al. 2003. A role for cytoplasmic dynein and LIS1 in directed cell movement. J. Cell Biol. 163:1205-11
19. Dujardin DL, Vallee RB. 2002. Dynein at the cortex. Curr. Opin. Cell Biol. 14:44-49
20. Duncan JE, Warrior R. 2002. The cytoplasmic dynein and kinesin motors have interdependent roles in patterning the Drosophila oocyte. Curr. Biol. 12:1982-91
21. Ebneth A, Godemann R, Stamer K, Illenberger S, Trinczek B, et al. 1998. Overexpression of tau protein inhibits kinesin-dependent trafficking of vesicles, mitochondria, and endoplasmic reticulum - implications for Alzheimers-disease. J. Cell Biol. 143:777-94
22. Echeverri CJ, Paschal BM, Vaughan KT, Vallee RB. 1996. Molecular characterization of 50 kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis. J. Cell Biol. 132:617-33
23. Echeverri CJ, Vallee RB. 1996. Domain analysis of dynamitin, the 50 kD subunit of dynactin. Mol. Biol. Cell 7:404a (Abst.)
24. Eckley DM, Gill SR, Melkonian KA, Bingham JB, Goodson HV, et al. 1999. Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the Arp1 filament pointed end. J. Cell Biol. 147:307-19
25. Eckley DM, Schroer TA. 2003. Interactions between the evolutionarily conserved, actin-related protein, Arp11, actin, and Arp1. Mol. Biol. Cell 14:2645-54
26. Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, et al. 1997. Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum. Mol. Genet. 6:2205-12
27. Gaglio T, Dionne MA, Compton DA. 1997. Mitotic spindle poles are organized by structural and motor proteins in addition to centrosomes. J. Cell Biol. 138:1055-66
28. Garces JA, Clark IB, Meyer DI, Vallee RB. 1999. Interaction of the p62 subunit of dynactin with Arp1 and the cortical actin cytoskeleton. Curr. Biol. 9:1497-500
29. Garcia-Mata R, Gao YS, Sztul E. 2002. Hassles with taking out the garbage: aggravating aggresomes. Traffic 3:388-96
30. Geiser JR, Schott EJ, Kingsbury TJ, Cole NB, Totis LJ, et al. 1997. Saccharomyces cerevisiae genes required in the absence of the CIN8-encoded spindle motor act in functionally diverse mitotic pathways. Mol. Biol. Cell 8:1035-50
31. Gill SR, Schroer TA, Szilak I, Steuer ER, Sheetz MP, et al. 1991. Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J. Cell Biol. 115:1639-50
32. Gonczy P, Pichler S, Kirkham M, Hyman AA. 1999. Cytoplasmic dynein is required for distinct aspects of MTOC positioning, including centrosome separation, in the one cell stage Caenorhabditis elegans embryo. J. Cell Biol. 147:135-50
33. Grieshaber SS, Grieshaber NA, Hackstadt T. 2003. Chlamydia trachomatis uses host cell dynein to traffic to the microtubule-organizing center in a p50 dynamitin-independent process. J. Cell Sci. 116:3793-802
34. Guignot J, Caron E, Beuzon C, Bucci C, Kagan J, et al. 2004. Microtubule motors control membrane dynamics of Salmonella-containing vacuoles. J. Cell Sci. 117:1033-45
35. Habermann A, Schroer TA, Griffiths G, Burkhardt JK. 2001. Immunolocalization of cytoplasmic dynein and dynactin subunits in cultured macrophages: enrichment on early endocytic organelles. J. Cell Sci. 114:229-40
36. Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, et al. 2003. Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science 300:808-12
37. Helfand BT, Chang L, Goldman RD. 2004. Intermediate filaments are dynamic and motile elements of cellular architecture. J. Cell Sci. 117:133-41
38. Helfand BT, Loomis P, Yoon M, Goldman RD. 2003. Rapid transport of neural intermediate filament protein. J. Cell Sci. 116:2345-59
39. Helfand BT, Mikami A, Vallee RB, Goldman RD. 2002. A requirement for cytoplasmic dynein and dynactin in intermediate filament network assembly and organization. J. Cell Biol. 157:795-806
40. Holleran EA, Karki S, Holzbaur EL. 1998. The role of the dynactin complex in intracellular motility. Int. Rev. Cytol. 182:69-109
41. Holleran EA, Ligon LA, Tokito M, Stankewich MC, Morrow JS, et al. 2001. beta III spectrin binds to the Arp1 subunit of dynactin. J. Biol. Chem. 276:36598-605
42. Holleran EA, Tokito MK, Karki S, Holzbaur ELF. 1996. Centractin (Arp1) associates with spectrin revealing a potential mechanism to link dynactin to intracellular organelles. J. Cell Biol. 135:1815-29
43. Holzbaur ELF, Hammarback JA, Paschal BM, Kravit NG, Pfister KK, et al. 1991. Homology of a 150K cytoplasmic dynein-associated polypeptide with the Drosophila gene Glued. Nature 351:579-83
44. Hoogenraad CC, Akhmanova A, Howell SA, Dortland BR, De Zeeuw CI, et al. 2001. Mammalian Golgi-associated Bicaudal-D2 functions in the dynein-dynactin pathway by interacting with these complexes. EMBO J. 20:4041-54
45. Hoogenraad CC, Wulf P, Schiefermeier N, Stepanova T, Galjart N, et al. 2003. Bicaudal D induces selective dynein-mediated microtubule minus end-directed transport. EMBO J. 22:6004-15
46. Januschke J, Gervais L, Dass S, Kaltschmidt JA, Lopez-Schier H, et al. 2002. Polar transport in the Drosophila oocyte requires Dynein and Kinesin I cooperation. Curr. Biol. 12:1971-81
47. Jin T, Yue L, Li J. 2001. In vivo interaction between dynamitin and MacMARCKS detected by the fluorescent resonance energy transfer method. J. Biol. Chem. 276:12879-84
48. Johnston JA, Illing ME, Kopito RR. 2002. Cytoplasmic dynein/dynactin mediates the assembly of aggresomes. Cell Motil. Cytoskelet. 53:26-38
49. Jordens I, Fernandez-Borja M, Marsman M, Dusseljee S, Janssen L, et al. 2001. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr. Biol. 11:1680-95
50. Kahana JA, Schlenstedt G, Evanchuk DM, Geiser JR, Hoyt MA, et al. 1998. The yeast dynactin complex is involved in partitioning the mitotic spindle between mother and daughter cells during anaphase B. Mol. Biol. Cell 9:1741-56
51. Karki S, Holzbaur ELF. 1995. Affinity chromatography demonstrates a direct binding between cytoplasmic dynein and the dynactin complex. J. Biol. Chem. 270:28806-11
52. Karki S, LaMonte B, Holzbaur ELF. 1998. Characterization of the p22 subunit of dynactin reveals the localization of cytoplasmic dynein and dynactin to the midbody of dividing cells. J. Cell Biol. 142:1023-34
53. Karki S, Tokito MK, Holzbaur EL. 2000. A dynactin subunit with a highly conserved cysteine-rich motif interacts directly with Arp1. J. Biol. Chem. 275:4834-39
54. King SJ, Brown CL, Maier KC, Quintyne NJ, Schroer TA. 2003. Analysis of the dynein-dynactin interaction in vitro and in vivo. Mol. Biol. Cell 14:5089-97
55. King SJ, Schroer TA. 2000. Dynactin increases the processivity of the cytoplasmic dynein motor. Nat. Cell Biol. 2:20-24
56. Kloc M, Zearfoss NR, Etkin LD. 2002. Mechanisms of subcellular mRNA localization. Cell 108:533-44
57. Kopito R. 2003. The missing linker: an unexpected role for a histone deacetylase. Mol. Cell 12:1349-51
58. Kuhle V, Jackel D, Hensel M. 2004. Effector proteins encoded by Salmonella pathogenicity island 2 interfere with the microtubule cytoskeleton after translocation into host cells. Traffic 5:356-70
59. Kumar S, Zhou Y, Plamann M. 2001. Dynactin-membrane interaction is regulated by the C-terminal domains of p150(Glued). EMBO Rep. 2:939-44
60. Lafont F, Burkhardt JK, Simons K. 1994. Involvement of microtubule motors in basolateral and apical transport in kidney cells. Nature 372:801-3
61. Lane JD, Vergnolle MA, Woodman PG, Allan VJ. 2001. Apoptotic cleavage of cytoplasmic dynein intermediate chain and p150(Glued) stops dynein-dependent membrane motility. J. Cell Biol. 153:1415-26
62. Lange BM. 2002. Integration of the centrosome in cell cycle control, stress response and signal transduction pathways. Curr. Opin. Cell Biol. 14:35-43
63. Lee IH, Kumar S, Plamann M. 2001. Null mutants of the Neurospora actin-related protein 1 pointed-end complex show distinct phenotypes. Mol. Biol. Cell 12:2195-206
64. Li S, Finley J, Liu ZJ, Qiu SH, Chen H, et al. 2002. Crystal structure of the cytoskeleton-associated protein (CAP-Gly) domain. J. Biol. Chem. 277:48596-601
65. Li SH, Gutekunst CA, Hersch SM, Li XJ. 1998. Interaction of Huntingtin-associated protein with dynactin P150Glued. J. Neurosci. 18:1261-69
66. Liang Y, Yu W, Li Y, Yang Z, Yan X, et al. 2004. Nude1 functions in membrane traffic mainly through association with Lis1 and cytoplasmic dynein. J. Cell Biol. 164:557-66
67. Ligon LA, Shelly SS, Tokito M, Holzbaur EL. 2003. The microtubule plus-end proteins EB1 and dynactin have differential effects on microtubule polymerization. Mol. Biol. Cell 14:1405-17
68. MacDougall N, Clark A, MacDougall E, Davis I. 2003. Drosophila gurken (TGFalpha) mRNA localizes as particles that move within the oocyte in two dynein-dependent steps. Dev. Cell 4:307-19
69. Matanis T, Akhmanova A, Wulf P, Del Nery E, Weide T, et al. 2002. Bicaudal-D regulates COPI-independent Golgi-ER transport by recruiting the dynein-dynactin motor complex. Nat. Cell Biol. 4:986-92
70. Matteoni R, Kreis TE. 1987. Translocation and clustering of endosomes and lysosomes depends on microtubules. J. Cell Biol. 105:1253-65
71. McDonald D, Vodicka MA, Lucero G, Svitkina TM, Borisy GG, et al. 2002. Visualization of the intracellular behavior of HIV in living cells. J. Cell Biol. 159:441-52
72. McGrail M, Gepner J, Silvanovich A, Ludmann S, Serr M, et al. 1995. Regulation of cytoplasmic dynein function in vivo by the Drosophila Glued complex. J. Cell Biol. 131:411-25
73. McMillan JN, Tatchell K. 1994. The JNM1 gene in the yeast Saccharomyces cerevisiae is required for nuclear migration and spindle orientation during the mitotic cell cycle. J. Cell Biol. 125:143-58
74. Melki R, Vainberg IE, Chow RL, Cowan NJ. 1993. Chaperonin-mediated folding of vertebrate actin-related protein and γ-tubulin. J. Cell Biol. 122:1301-10
75. Morris JA, Kandpal G, Ma L, Austin CP. 2003. DISCI (Disrupted-In- Schizophrenia 1) is a centrosome-associated protein that interacts with MAP1A, MIPT3, ATF4/5 and NUDEL: regulation and loss of interaction with mutation. Hum. Mol. Genet. 12:1591-608
76. Muresan V, Stankewich MC, Steffen W, Morrow JS, Holzbaur EL, et al. 2001. Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins: a role for spectrin and acidic phospholipids. Mol. Cell 7:173-83
77. Ozeki Y, Tomoda T, Kleiderlein J, Kamiya A, Bord L, et al. 2003. Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth. Proc. Natl. Acad. Sci. USA 100:289-94
78. Parisi G, Fornasari M, Echave J. 2004. Dynactins p25 and p27 would be LbH proteins. FEBS Lett. 562:1-4
79. Park J-H. 2003. Roles for the dynactin complex in the glucocorticoid receptor signaling pathway. PhD thesis. The Johns Hopkins Univ. 291 pp.
80. Glued and a novel actin. J. Biol. Chem. 268:15318-23
81. Payne C, Rawe V, Ramalho-Santos J, Simerly C, Schatten G. 2003. Preferentially localized dynein and perinuclear dynactin associate with nuclear pore complex proteins to mediate genomic union during mammalian fertilization. J. Cell Sci. 116:4727-38
82. Pfister KK, Benashski SE, Dillman JF III, Patel-King RS, King SM. 1998. Identification and molecular characterization of the p24 dynactin light chain. Cell. Motil. Cytoskelet. 41:154-67
83. Presley JF, Zaal KJM, Schroer TA, Cole NB, Lippincott-Schwartz J. 1997. ER to Golgi transport visualized in living cells. Nature 389:81-85
84. Puls I, Jonnakuty C, LaMonte BH, Holzbaur EL, Tokito M, et al. 2003. Mutant dynactin in motor neuron disease. Nat. Genet. 33:455-56
85. Quintyne NJ, Gill SR, Eckley DM, Crego CL, Compton DA, et al. 1999. Dynactin is required for microtubule anchoring at fibroblast centrosomes. J. Cell Biol. 147:321-34
86. Quintyne NJ, Schroer TA. 2002. Distinct cell cycle-dependent roles for dynactin and dynein at centrosomes. J Cell Biol. 159:245-54
87. Reinsch S, Karsenti E. 1997. Movement of nuclei along microtubules in Xenopus egg extracts. Curr. Biol. 7:211-14
88. Riehemann K, Sorg C. 1993. Sequence homologies between four cytoskeleton-associated proteins. Trends Biochem. Sci. 18:82-83
89. Salina D, Bodoor K, Eckley DM, Schroer TA, Rattner JB, et al. 2002. Cytoplasmic dynein as a facilitator of nuclear envelope breakdown. Cell 108:97-107
90. Schafer DA, Gill SR, Cooper JA, Heuser JE, Schroer TA. 1994a. Ultrastructural analysis of the dynactin complex: An actin-related protein is a component of a filament that resembles F-actin. J. Cell Biol. 126:403-12
91. Schafer DA, Korshunova YO, Schroer TA, Cooper JA. 1994b. Differential localization and sequence analysis of capping protein β-subunit isoforms of vertebrates. J. Cell Biol. 127:453-65
92. Scheich C, Niesen FH, Seckler R, Bussow K. 2004. An automated in vitro protein folding screen applied to a human dynactin subunit. Protein Sci. 13:370-80
93. Schnapp BJ, Reese TS. 1989. Dynein is the motor for retrograde axonal transport of organelles. Proc. Natl. Acad. Sci. USA 86:1548-52
94. Schrader M, King SJ, Stroh TA, Schroer TA. 2000. Real time imaging reveals a peroxisomal reticulum in living cells. J. Cell Sci. 113:3663-71
95. Schroer TA. 1994. New insights into the interaction of cytoplasmic dynein with the actin-related protein, Arp1. J. Cell Biol. 127:1-4
96. Schroer TA, Sheetz MP. 1991. Two activators of microtubule-based vesicle transport. J. Cell Biol. 115:1309-18
97. Schuyler SC, Pellman D. 2001. Microtubule "plus-end-tracking proteins": The end is just the beginning. Cell 105:421-24
98. Short B, Preisinger C, Schaletzky J, Kopajtich R, Barr FA. 2002. The Rab6 GTPase regulates recruitment of the dynactin complex to Golgi membranes. Curr. Biol. 12:1792-95
99. Skop A, White J. 1998. The dynactin complex is required for cleavage plane specification in early Caenorhabditis elegans embryos. Curr. Biol. 8:1110-16
100. Smith GA, Enquist LW. 2002. Break ins and break outs: viral interactions with the cytoskeleton of mammalian cells. Annu. Rev. Cell Dev. Biol. 18:135-61
101. Starr DA, Williams BC, Hays TS, Goldberg ML. 1998. ZW10 helps recruit dynactin and dynein to the kinetochore. J. Cell Biol. 142:763-74
102. Steffen W, Karki S, Vaughan KT, Vallee RB, Holzbaur EL, et al. 1997. The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes. Mol. Biol. Cell 8:2077-88
103. Suomalainen M, Nakano MY, Keller S, Boucke K, Stidwill RP, et al. 1999. Microtubule-dependent plus- and minus end-directed motilities are competing processes for nuclear targeting of adenovirus. J. Cell Biol. 144:657-72
104. Swaroop A, Swaroop M, Garen A. 1987. Sequence analysis of the complete cDNA and encoded polypeptide for the glued gene of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 84:6501-5
105. Tai AW, Chuang JZ, Bode C, Wolfrum U, Sung CH. 1999. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. Cell 97:877-87
106. Tokito MK, Holzbaur EL. 1998. The genomic structure of DCTN1, a candidate gene for limb-girdle muscular dystrophy (LGMD2B). Biochim. Biophys. Acta 1442:432-36
107. Tokito MK, Howland DS, Lee VM-Y, Holzbaur ELF. 1996. Functionally distinct isoforms of dynactin are expressed in human neurons. Mol. Biol. Cell 7:1167-80
108. Tynan SH, Purohit A, Doxsey SJ, Vallee RB. 2000. Light intermediate chain 1 defines a functional subfraction of cytoplasmic dynein which binds to pericentrin. J. Biol. Chem. 275:32763-68
109. Valetti C, Wetzel DM, Schrader M, Hasbani MJ, Gill SR, et al. 1999. Role of dynactin in endocytic traffic: effects of dynamitin overexpression and colocalization with CLIP-170. Mol. Biol. Cell 10:4107-20
110. Vaughan KT, Tynan SH, Faulkner NE, Echeverri CJ, Vallee RB. 1999. Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends. J. Cell Sci. 112:1437-47
111. Glued. J. Cell Biol. 131:1507-16
112. Vaughan PS, Miura P, Henderson M, Byrne B, Vaughan KT. 2002. A role for regulated binding of p150(Glued) to microtubule plus ends in organelle transport. J. Cell Biol. 158:305-19
113. Walczak CE, Vernos I, Mitchison TJ, Karsenti E, Heald R. 1998. A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity. Curr. Biol. 8:903-13
114. Wang L, Ho CL, Sun D, Liem RK, Brown A. 2000. Rapid movement of axonal neurofilaments interrupted by prolonged pauses. Nat. Cell Biol. 2:137-41
115. Wang Y, Jerdeva G, Yarber FA, da Costa SR, Xie J, et al. 2003. Cytoplasmic dynein participates in apically targeted stimulated secretory traffic in primary rabbit lacrimal acinar epithelial cells. J. Cell Sci. 116:2051-65
116. Waterman-Storer CM, Karki S, Holzbaur EL. 1995. The p150Glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1). Proc. Natl. Acad. Sci. USA 92:1634-38
117. Wiemer EA, Wenzel T, Deerinck TJ, Ellisman MH, Subramani S. 1997. Visualization of the peroxisomal compartment in living mammalian cells: dynamic behavior and association with microtubules. J. Cell Biol. 136:71-80
118. Wilkie GS, Davis I. 2001. Drosophila wingless and pair-rule transcripts localize apically by dynein-mediated transport of RNA particles. Cell 105:209-19
119. Xiang X, Plamann M. 2003. Cytoskeleton and motor proteins in filamentous fungi. Curr. Opin. Microbiol. 6:628-33
120. Yamamoto A, Hiraoka Y. 2003. Cytoplasmic dynein in fungi: insights from nuclear migration. J. Cell Sci. 116:4501-12
121. Young A, Dictenberg JB, Purohit A, Tuft R, Doxsey SJ. 2000. Cytoplasmic dynein-mediated assembly of pericentrin and gamma tubulin onto centrosomes. Mol. Biol. Cell 11:2047-56
122. Young MR, D'Arcy Hart P. 1986. Movements and other distinguishing features of small vesicles identified by darkfield microscopy in living macrophages. Exp. Cell Res. 164:199-210
123. Yue L, Lu S, Garces J, Jin T, Li J. 2000. Protein kinase C-regulated dynamitin-macrophage-enriched myristoylated alanine-rice C kinase substrate interaction is involved in macrophage cell spreading. J. Biol. Chem. 275:23948-56
124. Ziegelbauer J, Shan B, Yager D, Larabell C, Hoffmann B, et al. 2001. Transcription factor MIZ-1 is regulated via microtubule association. Mol. Cell 8:339-49
125. Zimmerman W, Doxsey SJ. 2000. Construction of centrosomes and spindle poles by molecular motor-driven assembly of protein particles. Traffic 1:927-34