-
1
-
-
0034927081
-
Neurotrophins: Roles in neuronal development and function
-
Huang, E. J. & Reichardt, L. F. Neurotrophins: roles in neuronal development and function. Annu. Rev. Neurosci. 24, 677-736 (2001).
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 677-736
-
-
Huang, E.J.1
Reichardt, L.F.2
-
2
-
-
0034941330
-
Nerve growth factor signaling, neuroprotection, and neural repair
-
Sofroniew, M. V, Howe, C. L. & Mobley, W. C. Nerve growth factor signaling, neuroprotection, and neural repair. Annu. Rev. Neurosci. 24, 1217-1281 (2001).
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 1217-1281
-
-
Sofroniew, M.V.1
Howe, C.L.2
Mobley, W.C.3
-
3
-
-
0041488911
-
Trk receptors: Roles in neuronal signal transduction
-
Huang, E. J. & Reichardt, L. F. Trk receptors: roles in neuronal signal transduction. Annu. Rev. Biochem. 72, 609-642 (2003).
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 609-642
-
-
Huang, E.J.1
Reichardt, L.F.2
-
5
-
-
0027324447
-
The history of the discovery of the nerve growth factor
-
Hamburger, V. The history of the discovery of the nerve growth factor. J. Neurobiol. 24, 893-897 (1993).
-
(1993)
J. Neurobiol.
, vol.24
, pp. 893-897
-
-
Hamburger, V.1
-
6
-
-
78651025304
-
Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions
-
Hamburger, V. & Levi-Montalcini, R. Proliferation, differentiation and degeneration in the spinal ganglia of the chick embryo under normal and experimental conditions. J. Exp. Zool. 111, 457-501 (1949).
-
(1949)
J. Exp. Zool.
, vol.111
, pp. 457-501
-
-
Hamburger, V.1
Levi-Montalcini, R.2
-
7
-
-
0023236055
-
The nerve growth factor 35 years later
-
Levi-Montalcini, R. The nerve growth factor 35 years later. Science 237, 1154-1162 (1987).
-
(1987)
Science
, vol.237
, pp. 1154-1162
-
-
Levi-Montalcini, R.1
-
8
-
-
0024336393
-
The neurotrophic theory and naturally occurring motoneuron death
-
Oppenheim, R. W. The neurotrophic theory and naturally occurring motoneuron death. Trends Neurosci. 12, 252-255 (1989).
-
(1989)
Trends Neurosci.
, vol.12
, pp. 252-255
-
-
Oppenheim, R.W.1
-
9
-
-
0028238769
-
Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
-
Snider, W. D. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77, 627-638 (1994).
-
(1994)
Cell
, vol.77
, pp. 627-638
-
-
Snider, W.D.1
-
10
-
-
0016810608
-
The effects of axotomy on the development of the rat superior cervical ganglion
-
Hendry, I. A. The effects of axotomy on the development of the rat superior cervical ganglion. Brain Res. 90, 235-244 (1975).
-
(1975)
Brain Res.
, vol.90
, pp. 235-244
-
-
Hendry, I.A.1
-
11
-
-
1842313862
-
Local control of neurite development by nerve growth factor
-
Campenot, R. B. Local control of neurite development by nerve growth factor. Proc. Natl Acad. Sci. USA 74, 4516-4519 (1977).
-
(1977)
Proc. Natl Acad. Sci. USA
, vol.74
, pp. 4516-4519
-
-
Campenot, R.B.1
-
12
-
-
0031845159
-
Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation
-
Deckwerth, T. L., Easton, R. M., Knudson, C. M., Korsmeyer, S. J. & Johnson, E. M. Jr. Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation. Exp. Neurol. 152, 150-162 (1998).
-
(1998)
Exp. Neurol.
, vol.152
, pp. 150-162
-
-
Deckwerth, T.L.1
Easton, R.M.2
Knudson, C.M.3
Korsmeyer, S.J.4
Johnson Jr., E.M.5
-
13
-
-
0032192529
-
Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c
-
Deshmukh, M. & Johnson, E. M. Jr. Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c. Neuron 21, 695-705 (1998).
-
(1998)
Neuron
, vol.21
, pp. 695-705
-
-
Deshmukh, M.1
Johnson Jr., E.M.2
-
14
-
-
0033579301
-
Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons
-
Riccio, A., Ahn, S., Davenport, C. M., Blendy, J. A. & Ginty, D. D. Mediation by a CREB family transcription factor of NGF-dependent survival of sympathetic neurons. Science 286, 2358-2361 (1999).
-
(1999)
Science
, vol.286
, pp. 2358-2361
-
-
Riccio, A.1
Ahn, S.2
Davenport, C.M.3
Blendy, J.A.4
Ginty, D.D.5
-
15
-
-
0032212257
-
Developmental regulation of apoptosis in dorsal root ganglion neurons
-
Vogelbaum, M. A., Tong, J. X. & Rich, K. M. Developmental regulation of apoptosis in dorsal root ganglion neurons. J. Neurosci. 18, 8928-8935 (1998).
-
(1998)
J. Neurosci.
, vol.18
, pp. 8928-8935
-
-
Vogelbaum, M.A.1
Tong, J.X.2
Rich, K.M.3
-
16
-
-
0037171782
-
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB
-
Lonze, B. E., Riccio, A., Cohen, S. & Ginty, D. D. Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron 34, 371-385 (2002).
-
(2002)
Neuron
, vol.34
, pp. 371-385
-
-
Lonze, B.E.1
Riccio, A.2
Cohen, S.3
Ginty, D.D.4
-
17
-
-
0030801304
-
An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons
-
Riccio, A., Pierchala, B. A., Ciarallo, C. L & Ginty, D. D. An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons. Science 277, 1097-1100 (1997).
-
(1997)
Science
, vol.277
, pp. 1097-1100
-
-
Riccio, A.1
Pierchala, B.A.2
Ciarallo, C.L.3
Ginty, D.D.4
-
18
-
-
0033568881
-
Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex
-
Watson, F. L. et al. Rapid nuclear responses to target-derived neurotrophins require retrograde transport of ligand-receptor complex. J. Neurosci. 19, 7889-7900 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 7889-7900
-
-
Watson, F.L.1
-
19
-
-
0033694754
-
The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase
-
Atwal, J. K., Massie, B., Miller, F. D. & Kaplan, D. R. The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron 27, 265-277 (2000).
-
(2000)
Neuron
, vol.27
, pp. 265-277
-
-
Atwal, J.K.1
Massie, B.2
Miller, F.D.3
Kaplan, D.R.4
-
20
-
-
0033695838
-
Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons
-
Kuruvilla, R., Ye, H. & Ginty, D. D. Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons. Neuron 27, 499-512 (2000).
-
(2000)
Neuron
, vol.27
, pp. 499-512
-
-
Kuruvilla, R.1
Ye, H.2
Ginty, D.D.3
-
21
-
-
0034804675
-
Neurotrophins use the Erk5 pathway to mediate a retrograde survival response
-
Watson, F. L. et al. Neurotrophins use the Erk5 pathway to mediate a retrograde survival response. Nature Neurosci. 4, 981-988 (2001). Shows that distinct effector pathways are activated by local and retrograde neurotrophin signalling. Neurotrophin stimulation of axon terminals activates ERK1 and 2 locally in axons but neuronal survival responses are mediated by the retrograde activation of ERK5 in cell bodies.
-
(2001)
Nature Neurosci.
, vol.4
, pp. 981-988
-
-
Watson, F.L.1
-
22
-
-
0842348861
-
Heterogeneous requirement of NGF for sympathetic target innervation in vivo
-
Glebova, N. O. & Ginty, D. D. Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J. Neurosci. 24, 743-751 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 743-751
-
-
Glebova, N.O.1
Ginty, D.D.2
-
23
-
-
3242698182
-
A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling
-
Kuruvilla, R. et al. A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling. Cell 118, 243-255 (2004).
-
(2004)
Cell
, vol.118
, pp. 243-255
-
-
Kuruvilla, R.1
-
24
-
-
0033757828
-
Development of sensory neurons in the absence of NGF/TrkA signaling in vivo
-
Patel, T. D., Jackman, A., Rice, F. L, Kucera, J. & Snider, W. D. Development of sensory neurons in the absence of NGF/TrkA signaling in vivo. Neuron 25, 345-357 (2000).
-
(2000)
Neuron
, vol.25
, pp. 345-357
-
-
Patel, T.D.1
Jackman, A.2
Rice, F.L.3
Kucera, J.4
Snider, W.D.5
-
25
-
-
0038580908
-
Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents
-
Patel, T. D. et al. Peripheral NT3 signaling is required for ETS protein expression and central patterning of proprioceptive sensory afferents. Neuron 38, 403-416 (2003).
-
(2003)
Neuron
, vol.38
, pp. 403-416
-
-
Patel, T.D.1
-
26
-
-
0037101970
-
Function and regulation of CREB family transcription factors in the nervous system
-
Lonze, B. E. & Ginty, D. D. Function and regulation of CREB family transcription factors in the nervous system. Neuron 35, 605-623 (2002).
-
(2002)
Neuron
, vol.35
, pp. 605-623
-
-
Lonze, B.E.1
Ginty, D.D.2
-
27
-
-
0037806030
-
Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons
-
Graef, I. A. et al. Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell 113, 657-670 (2003).
-
(2003)
Cell
, vol.113
, pp. 657-670
-
-
Graef, I.A.1
-
28
-
-
0037194898
-
GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of specific motor neuron pools
-
Haase, G. et al. GDNF acts through PEA3 to regulate cell body positioning and muscle innervation of specific motor neuron pools. Neuron 35, 893-905 (2002).
-
(2002)
Neuron
, vol.35
, pp. 893-905
-
-
Haase, G.1
-
29
-
-
0024465771
-
Target size regulates calibre and myelination of sympathetic axons
-
Voyvodic, J. T. Target size regulates calibre and myelination of sympathetic axons. Nature 342, 430-433 (1989).
-
(1989)
Nature
, vol.342
, pp. 430-433
-
-
Voyvodic, J.T.1
-
30
-
-
0024359852
-
Peripheral target regulation of dendritic geometry in the rat superior cervical ganglion
-
Voyvodic, J. T. Peripheral target regulation of dendritic geometry in the rat superior cervical ganglion. J. Neurosci. 9, 1997-2010 (1989).
-
(1989)
J. Neurosci.
, vol.9
, pp. 1997-2010
-
-
Voyvodic, J.T.1
-
31
-
-
0025452844
-
Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse
-
Ruit, K. G., Osborne, P. A., Schmidt, R. E., Johnson, E. M. Jr. & Snider, W. D. Nerve growth factor regulates sympathetic ganglion cell morphology and survival in the adult mouse. J. Neurosci. 10, 2412-2419 (1990).
-
(1990)
J. Neurosci.
, vol.10
, pp. 2412-2419
-
-
Ruit, K.G.1
Osborne, P.A.2
Schmidt, R.E.3
Johnson Jr., E.M.4
Snider, W.D.5
-
32
-
-
0026323611
-
Administration or deprivation of nerve growth factor during development permanently alters neuronal geometry
-
Ruit, K. G. & Snider, W. D. Administration or deprivation of nerve growth factor during development permanently alters neuronal geometry. J. Comp. Neurol. 314, 106-113 (1991).
-
(1991)
J. Comp. Neurol.
, vol.314
, pp. 106-113
-
-
Ruit, K.G.1
Snider, W.D.2
-
33
-
-
0023765649
-
Nerve growth factor enhances dendritic arborization of sympathetic ganglion cells in developing mammals
-
Snider, W. D. Nerve growth factor enhances dendritic arborization of sympathetic ganglion cells in developing mammals. J. Neurosci. 8, 2628-2634 (1988).
-
(1988)
J. Neurosci.
, vol.8
, pp. 2628-2634
-
-
Snider, W.D.1
-
34
-
-
0029082799
-
Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons
-
Lein, P., Johnson, M., Quo, X., Rueger, D. & Higgins, D. Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons. Neuron 15, 597-605 (1995).
-
(1995)
Neuron
, vol.15
, pp. 597-605
-
-
Lein, P.1
Johnson, M.2
Quo, X.3
Rueger, D.4
Higgins, D.5
-
35
-
-
0016754637
-
Functional and structural changes in mammalian sympathetic neurones following interruption of their axons
-
Purves, D. Functional and structural changes in mammalian sympathetic neurones following interruption of their axons. J. Physiol. (Lond.) 252, 429-463 (1975).
-
(1975)
J. Physiol. (Lond.)
, vol.252
, pp. 429-463
-
-
Purves, D.1
-
36
-
-
0017078898
-
Functional and structural changes in mammalian sympathetic neurones following colchicine application to post-ganglionic nerves
-
Purves, D. Functional and structural changes in mammalian sympathetic neurones following colchicine application to post-ganglionic nerves. J. Physiol. (Lond.) 259, 159-175 (1976).
-
(1976)
J. Physiol. (Lond.)
, vol.259
, pp. 159-175
-
-
Purves, D.1
-
37
-
-
0019321644
-
Elimination of synapses in the developing nervous system
-
Purves, D. & Lichtman, J. W. Elimination of synapses in the developing nervous system. Science 210, 153-157 (1980).
-
(1980)
Science
, vol.210
, pp. 153-157
-
-
Purves, D.1
Lichtman, J.W.2
-
38
-
-
0017816844
-
The effects of nerve growth factor and its antiserum on synapses in the superior cervical ganglion of the guinea-pig
-
Nja, A. & Purves, D. The effects of nerve growth factor and its antiserum on synapses in the superior cervical ganglion of the guinea-pig. J. Physiol. (Lond.) 277, 55-75 (1978).
-
(1978)
J. Physiol. (Lond.)
, vol.277
, pp. 55-75
-
-
Nja, A.1
Purves, D.2
-
39
-
-
0031039772
-
Synaptic innervation density is regulated by neuron-derived BDNF
-
Causing, C. G. et al. Synaptic innervation density is regulated by neuron-derived BDNF. Neuron 18, 257-267 (1997).
-
(1997)
Neuron
, vol.18
, pp. 257-267
-
-
Causing, C.G.1
-
40
-
-
0028795367
-
Neuronal and nonneuronal expression of neurotrophins and their receptors in sensory and sympathetic ganglia suggest new intercellular trophic interactions
-
Wetmore, C. & Olson, L. Neuronal and nonneuronal expression of neurotrophins and their receptors in sensory and sympathetic ganglia suggest new intercellular trophic interactions. J. Comp. Neurol. 353, 143-159 (1995).
-
(1995)
J. Comp. Neurol.
, vol.353
, pp. 143-159
-
-
Wetmore, C.1
Olson, L.2
-
41
-
-
17344367304
-
TrkB and neurotrophin-4 are important for development and maintenance of sympathetic preganglionic neurons innervating the adrenal medulla
-
Schober, A. et al. TrkB and neurotrophin-4 are important for development and maintenance of sympathetic preganglionic neurons innervating the adrenal medulla. J. Neurosci. 18, 7272-7284 (1998).
-
(1998)
J. Neurosci.
, vol.18
, pp. 7272-7284
-
-
Schober, A.1
-
42
-
-
0032894559
-
Expression of neurotrophin receptors trkB and trkC and their ligands in rat adrenal gland and the intermediolateral column of the spinal cord
-
Schober, A. et al. Expression of neurotrophin receptors trkB and trkC and their ligands in rat adrenal gland and the intermediolateral column of the spinal cord. Cell Tissue Res. 296, 271-279 (1999).
-
(1999)
Cell Tissue Res.
, vol.296
, pp. 271-279
-
-
Schober, A.1
-
43
-
-
0035341260
-
Lack of neurotrophin-4 causes selective structural and chemical deficits in sympathetic ganglia and their preganglionic innervation
-
Roosen, A. et al. Lack of neurotrophin-4 causes selective structural and chemical deficits in sympathetic ganglia and their preganglionic innervation. J. Neurosci. 21, 3073-3084 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 3073-3084
-
-
Roosen, A.1
-
44
-
-
0021229536
-
Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: Specificity and level of regulation
-
Acheson, A. L., Naujoks, K. & Thoenen, H. Nerve growth factor-mediated enzyme induction in primary cultures of bovine adrenal chromaffin cells: specificity and level of regulation. J. Neurosci. 4, 1771-1780 (1984).
-
(1984)
J. Neurosci.
, vol.4
, pp. 1771-1780
-
-
Acheson, A.L.1
Naujoks, K.2
Thoenen, H.3
-
45
-
-
0017651337
-
Selective induction of tyrosine hydroxylase and dopamine β-hydroxylase by nerve growth factor: Comparison between adrenal medulla and sympathetic ganglia of adult and newborn rats
-
Otten, U., Schwab, M., Gagnon, C. & Thoenen, H. Selective induction of tyrosine hydroxylase and dopamine β-hydroxylase by nerve growth factor: comparison between adrenal medulla and sympathetic ganglia of adult and newborn rats. Brain Res. 133, 291-303 (1977).
-
(1977)
Brain Res.
, vol.133
, pp. 291-303
-
-
Otten, U.1
Schwab, M.2
Gagnon, C.3
Thoenen, H.4
-
46
-
-
0033004556
-
Cellular and molecular determinants of sympathetic neuron development
-
Francis, N. J. & Landis, S. C. Cellular and molecular determinants of sympathetic neuron development. Annu. Rev. Neurosci. 22, 541-566 (1999).
-
(1999)
Annu. Rev. Neurosci.
, vol.22
, pp. 541-566
-
-
Francis, N.J.1
Landis, S.C.2
-
47
-
-
0029061444
-
NGF-stimulated retrograde transport of trkA in the mammalian nervous system
-
Ehlers, M. D., Kaplan, D. R., Price, D. L. & Koliatsos, V. E. NGF-stimulated retrograde transport of trkA in the mammalian nervous system. J. Cell Biol. 130, 149-156 (1995).
-
(1995)
J. Cell Biol.
, vol.130
, pp. 149-156
-
-
Ehlers, M.D.1
Kaplan, D.R.2
Price, D.L.3
Koliatsos, V.E.4
-
48
-
-
0026022964
-
Dissecting the mode of action of a neuronal growth factor
-
Halegoua, S., Armstrong, R. C. & Kremer, N. E. Dissecting the mode of action of a neuronal growth factor. Curr. Top. Microbiol. Immunol. 165, 119-170 (1991).
-
(1991)
Curr. Top. Microbiol. Immunol.
, vol.165
, pp. 119-170
-
-
Halegoua, S.1
Armstrong, R.C.2
Kremer, N.E.3
-
49
-
-
0015980737
-
The retrograde axonal transport of nerve growth factor
-
Hendry, I. A., Stockel, K., Thoenen, H. & Iversen, L. L. The retrograde axonal transport of nerve growth factor. Brain Res. 68, 103-121 (1974).
-
(1974)
Brain Res.
, vol.68
, pp. 103-121
-
-
Hendry, I.A.1
Stockel, K.2
Thoenen, H.3
Iversen, L.L.4
-
50
-
-
0029925240
-
NTR and trkB receptors
-
NTR and trkB receptors. J. Neurosci. 16, 2995-3008 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 2995-3008
-
-
Von Bartheld, C.S.1
-
51
-
-
0022975298
-
Comparative dynamics of retrograde transport of nerve growth factor and horseradish peroxidase in rat lumbar dorsal root ganglia
-
Yip, H. K. & Johnson, E. M. Jr. Comparative dynamics of retrograde transport of nerve growth factor and horseradish peroxidase in rat lumbar dorsal root ganglia. J. Neurocytol. 15, 789-798 (1986).
-
(1986)
J. Neurocytol.
, vol.15
, pp. 789-798
-
-
Yip, H.K.1
Johnson Jr., E.M.2
-
52
-
-
0036606330
-
Retrograde neurotrophin signaling: Trk-ing along the axon
-
Ginty, D. D. & Segal, R. A. Retrograde neurotrophin signaling: Trk-ing along the axon. Curr. Opin. Neurobiol. 12, 268-274 (2002).
-
(2002)
Curr. Opin. Neurobiol.
, vol.12
, pp. 268-274
-
-
Ginty, D.D.1
Segal, R.A.2
-
53
-
-
0037899138
-
Evidence in support of signaling endosome-based retrograde survival of sympathetic neurons
-
Ye, H., Kuruvilla, R., Zweifel, L S. & Ginty, D. D. Evidence in support of signaling endosome-based retrograde survival of sympathetic neurons. Neuron 39, 57-68 (2003).
-
(2003)
Neuron
, vol.39
, pp. 57-68
-
-
Ye, H.1
Kuruvilla, R.2
Zweifel, L.S.3
Ginty, D.D.4
-
54
-
-
0030861966
-
Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures
-
Senger, D. L. & Campenot, R. B. Rapid retrograde tyrosine phosphorylation of trkA and other proteins in rat sympathetic neurons in compartmented cultures. J. Cell Biol. 138, 411-421 (1997).
-
(1997)
J. Cell Biol.
, vol.138
, pp. 411-421
-
-
Senger, D.L.1
Campenot, R.B.2
-
55
-
-
2542421751
-
Dynein motors transport activated Trks to promote survival of target-dependent neurons
-
Heerssen, H. M., Pazyra, M. F. & Segal, R. A. Dynein motors transport activated Trks to promote survival of target-dependent neurons. Nature Neurosci. 7, 596-604 (2004).
-
(2004)
Nature Neurosci.
, vol.7
, pp. 596-604
-
-
Heerssen, H.M.1
Pazyra, M.F.2
Segal, R.A.3
-
56
-
-
19444366758
-
Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors
-
Valdez, G. et al. Pincher-mediated macroendocytosis underlies retrograde signaling by neurotrophin receptors. J. Neurosci. 25, 5236-5247 (2005).
-
(2005)
J. Neurosci.
, vol.25
, pp. 5236-5247
-
-
Valdez, G.1
-
57
-
-
0034255428
-
Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation
-
Zhang, Y, Moheban, D. B., Conway, B. R., Bhattacharyya, A. & Segal, R. A. Cell surface Trk receptors mediate NGF-induced survival while internalized receptors regulate NGF-induced differentiation. J. Neurosci. 20, 5671-5678 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 5671-5678
-
-
Zhang, Y.1
Moheban, D.B.2
Conway, B.R.3
Bhattacharyya, A.4
Segal, R.A.5
-
58
-
-
0037734370
-
Mutations in dynein link motor neuron degeneration to defects in retrograde transport
-
Hafezparast, M. et al. Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science 300, 808-812 (2003). Shows that mutations in dynein, which disrupt retrograde transport, lead to degeneration of projection neurons in mice.
-
(2003)
Science
, vol.300
, pp. 808-812
-
-
Hafezparast, M.1
-
59
-
-
0142090754
-
Spatial requirements for TrkA kinase activity in the support of neuronal survival and axon growth in rat sympathetic neurons
-
MacInnis, B. L., Senger, D. L. & Campenot, R. B. Spatial requirements for TrkA kinase activity in the support of neuronal survival and axon growth in rat sympathetic neurons. Neuropharmacology 45, 995-1010 (2003).
-
(2003)
Neuropharmacology
, vol.45
, pp. 995-1010
-
-
MacInnis, B.L.1
Senger, D.L.2
Campenot, R.B.3
-
60
-
-
0037154885
-
Retrograde support of neuronal survival without retrograde transport of nerve growth factor
-
MacInnis, B. L. & Campenot, R. B. Retrograde support of neuronal survival without retrograde transport of nerve growth factor. Science 295, 1536-1539 (2002).
-
(2002)
Science
, vol.295
, pp. 1536-1539
-
-
MacInnis, B.L.1
Campenot, R.B.2
-
61
-
-
0037899137
-
NGF signaling in sensory neurons: Evidence that early endosomes carry NGF retrograde signals
-
Delcroix, J. D. et al. NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals. Neuron 39, 69-84 (2003). Provides biochemical insight into the nature of the 'signalling endosomes' that carry NGF and TrkA. Using an intact nerve preparation, the authors isolated retrogradely transported NGF-TrkA-containing vesicles, which were shown to carry not only activated signalling effectors but also markers of early endosomes such as Rab5 and EEA1.
-
(2003)
Neuron
, vol.39
, pp. 69-84
-
-
Delcroix, J.D.1
-
62
-
-
0035426219
-
Nerve growth factor activates persistent Rap1 signaling in endosomes
-
Wu, C., Lai, C. F. & Mobley, W. C. Nerve growth factor activates persistent Rap1 signaling in endosomes. J. Neurosci. 21, 5406-5416 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 5406-5416
-
-
Wu, C.1
Lai, C.F.2
Mobley, W.C.3
-
63
-
-
0029152904
-
Retrograde axonal transport of signal transduction proteins in rat sciatic nerve
-
Johanson, S. O., Crouch, M. F. & Hendry, I. A. Retrograde axonal transport of signal transduction proteins in rat sciatic nerve. Brain Res. 690, 55-63 (1995).
-
(1995)
Brain Res.
, vol.690
, pp. 55-63
-
-
Johanson, S.O.1
Crouch, M.F.2
Hendry, I.A.3
-
64
-
-
4243333179
-
Axonal transport of activating transcription factor-2 is modulated by nerve growth factor in nociceptive neurons
-
Delcroix, J. D. et al. Axonal transport of activating transcription factor-2 is modulated by nerve growth factor in nociceptive neurons. J. Neurosci. 19, RC24 (1999).
-
(1999)
J. Neurosci.
, vol.19
-
-
Delcroix, J.D.1
-
65
-
-
0035105470
-
Regulation of receptor tyrosine kinase signaling by endocytic trafficking
-
Wiley, H. S. & Burke, P. M. Regulation of receptor tyrosine kinase signaling by endocytic trafficking. Traffic 2, 12-18 (2001).
-
(2001)
Traffic
, vol.2
, pp. 12-18
-
-
Wiley, H.S.1
Burke, P.M.2
-
66
-
-
0034307565
-
NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking
-
Beattie, E. C., Howe, C. L, Wilde, A., Brodsky, F. M. & Mobley, W. C. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. J. Neurosci. 20, 7325-7333 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 7325-7333
-
-
Beattie, E.C.1
Howe, C.L.2
Wilde, A.3
Brodsky, F.M.4
Mobley, W.C.5
-
67
-
-
0035819073
-
NGF signaling from clathrin-coated vesicles: Evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway
-
Howe, C. L., Valletta, J. S., Rusnak, A. S. & Mobley, W. C. NGF signaling from clathrin-coated vesicles: evidence that signaling endosomes serve as a platform for the Ras-MAPK pathway. Neuron 32, 801-814 (2001).
-
(2001)
Neuron
, vol.32
, pp. 801-814
-
-
Howe, C.L.1
Valletta, J.S.2
Rusnak, A.S.3
Mobley, W.C.4
-
68
-
-
0037684840
-
Caveolae/raft-dependent endocytosis
-
Nabi, I. R. & Le, P. U. Caveolae/raft-dependent endocytosis. J. Cell Biol. 161, 673-677 (2003).
-
(2003)
J. Cell Biol.
, vol.161
, pp. 673-677
-
-
Nabi, I.R.1
Le, P.U.2
-
69
-
-
0037071547
-
Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes
-
Shao, Y. et al. Pincher, a pinocytic chaperone for nerve growth factor/TrkA signaling endosomes. J. Cell Biol. 157, 679-691 (2002). This paper identifies a novel protein, Pincher, that promotes clathrin-independent macropinocytosis of NGF and TrkA.
-
(2002)
J. Cell Biol.
, vol.157
, pp. 679-691
-
-
Shao, Y.1
-
70
-
-
14544295742
-
Endocytosis of membrane receptors: Two pathways are better than one
-
Aguilar, R. C. & Wendland, B. Endocytosis of membrane receptors: two pathways are better than one. Proc. Natl Acad. Sci. USA 102, 2679-2680 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 2679-2680
-
-
Aguilar, R.C.1
Wendland, B.2
-
71
-
-
14544306526
-
Clathrin-independent endocytosis of ubiquitinated cargos
-
Sigismund, S. et al. Clathrin-independent endocytosis of ubiquitinated cargos. Proc. Natl Acad. Sci. USA 102, 2760-2765 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 2760-2765
-
-
Sigismund, S.1
-
73
-
-
0242361578
-
2+ influx
-
2+ influx. J. Cell Biol. 163, 385-395 (2003).
-
(2003)
J. Cell Biol.
, vol.163
, pp. 385-395
-
-
Du, J.1
-
74
-
-
0037424236
-
Trafficking of TrkA-green fluorescent protein chimerae during nerve growth factor-induced differentiation
-
Jullien, J. et al. Trafficking of TrkA-green fluorescent protein chimerae during nerve growth factor-induced differentiation. J. Biol. Chem. 278, 8706-8716 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 8706-8716
-
-
Jullien, J.1
-
75
-
-
0028170166
-
p75 nerve growth factor receptor modulates p140trkA kinase activity, but not ligand internalization, in PC12 cells
-
Kahle, P., Barker, P. A., Shooter, E. M. & Hertel, C. p75 nerve growth factor receptor modulates p140trkA kinase activity, but not ligand internalization, in PC12 cells. J. Neurosci. Res. 38, 599-606 (1994).
-
(1994)
J. Neurosci. Res.
, vol.38
, pp. 599-606
-
-
Kahle, P.1
Barker, P.A.2
Shooter, E.M.3
Hertel, C.4
-
76
-
-
14644394937
-
Differential endocytic sorting of p75NTR and TrkA in response to NGF: A role for late endosomes in TrkA trafficking
-
Saxena, S. et al. Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking. Mol. Cell. Neurosci. 28, 571-587 (2005).
-
(2005)
Mol. Cell. Neurosci.
, vol.28
, pp. 571-587
-
-
Saxena, S.1
-
78
-
-
0033538576
-
The structural era of endocytosis
-
Marsh, M. & McMahon, H. T. The structural era of endocytosis. Science 285, 215-220 (1999).
-
(1999)
Science
, vol.285
, pp. 215-220
-
-
Marsh, M.1
McMahon, H.T.2
-
79
-
-
0034698787
-
Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis
-
Confalonieri, S., Salcini, A. E., Puri, C., Tacchetti, C. & Di Fiore, P. P. Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis. J. Cell Biol. 150, 905-912 (2000).
-
(2000)
J. Cell Biol.
, vol.150
, pp. 905-912
-
-
Confalonieri, S.1
Salcini, A.E.2
Puri, C.3
Tacchetti, C.4
Di Fiore, P.P.5
-
80
-
-
0033525759
-
EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake
-
Wilde, A. et al. EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96, 677-687 (1999).
-
(1999)
Cell
, vol.96
, pp. 677-687
-
-
Wilde, A.1
-
81
-
-
20144387125
-
A chemical-genetic approach to studying neurotrophin signaling
-
Chen, X. et al. A chemical-genetic approach to studying neurotrophin signaling. Neuron 46, 13-21 (2005).
-
(2005)
Neuron
, vol.46
, pp. 13-21
-
-
Chen, X.1
-
82
-
-
0033216248
-
Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons
-
Tsui-Pierchala, B. A. & Ginty, D. D. Characterization of an NGF-P-TrkA retrograde-signaling complex and age-dependent regulation of TrkA phosphorylation in sympathetic neurons. J. Neurosci. 19, 8207-8218 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 8207-8218
-
-
Tsui-Pierchala, B.A.1
Ginty, D.D.2
-
83
-
-
0031017336
-
125I- nerve growth factor in rat sympathetic neurons in compartmented cultures
-
125I-nerve growth factor in rat sympathetic neurons in compartmented cultures. J. Neurosci. 17, 1282-1290 (1997).
-
(1997)
J. Neurosci.
, vol.17
, pp. 1282-1290
-
-
Ure, D.R.1
Campenot, R.B.2
-
84
-
-
0033849090
-
Signalling organelle for retrograde axonal transport of internalized neurotrophins from the nerve terminal
-
Sandow, S. L. et al. Signalling organelle for retrograde axonal transport of internalized neurotrophins from the nerve terminal. Immunol. Cell Biol. 78, 430-435 (2000).
-
(2000)
Immunol. Cell Biol.
, vol.78
, pp. 430-435
-
-
Sandow, S.L.1
-
85
-
-
1542334491
-
Comparison of nerve terminal events in vivo effecting retrograde transport of vesicles containing neurotrophins or synaptic vesicle components
-
Weible, M. W., 2nd, Ozsarac, N., Grimes, M. L. & Hendry, I. A. Comparison of nerve terminal events in vivo effecting retrograde transport of vesicles containing neurotrophins or synaptic vesicle components. J. Neurosci. Res. 75, 771-781 (2004).
-
(2004)
J. Neurosci. Res.
, vol.75
, pp. 771-781
-
-
Weible II, M.W.1
Ozsarac, N.2
Grimes, M.L.3
Hendry, I.A.4
-
86
-
-
0037096094
-
High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors
-
Bhattacharyya, A. et al. High-resolution imaging demonstrates dynein-based vesicular transport of activated Trk receptors. J. Neurobiol. 51, 302-312 (2002).
-
(2002)
J. Neurobiol.
, vol.51
, pp. 302-312
-
-
Bhattacharyya, A.1
-
87
-
-
0033776498
-
Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1
-
York, R. D. et al. Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. Mol. Cell. Biol. 20, 8069-8083 (2000).
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 8069-8083
-
-
York, R.D.1
-
88
-
-
0035975965
-
Modular phosphoinositide-binding domains - Their role in signalling and membrane trafficking
-
Cullen, P. J., Cozier, G. E., Banting, G. & Mellor, H. Modular phosphoinositide-binding domains - their role in signalling and membrane trafficking. Curr. Biol. 11, R882-R893 (2001).
-
(2001)
Curr. Biol.
, vol.11
-
-
Cullen, P.J.1
Cozier, G.E.2
Banting, G.3
Mellor, H.4
-
89
-
-
0032581654
-
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
-
Simonsen, A. et al. EEA1 links PI(3)K function to Rab5 regulation of endosome fusion. Nature 394, 494-498 (1998).
-
(1998)
Nature
, vol.394
, pp. 494-498
-
-
Simonsen, A.1
-
90
-
-
0033580299
-
The Rab5 effector EEA1 is a core component of endosome docking
-
Christoforidis, S., McBride, H. M., Burgoyne, R. D. & Zerial, M. The Rab5 effector EEA1 is a core component of endosome docking. Nature 397, 621-625 (1999).
-
(1999)
Nature
, vol.397
, pp. 621-625
-
-
Christoforidis, S.1
McBride, H.M.2
Burgoyne, R.D.3
Zerial, M.4
-
91
-
-
0029813779
-
Dynamic organization of endocytic pathways in axons of cultured sympathetic neurons
-
Overly, C. C. & Hollenbeck, P. J. Dynamic organization of endocytic pathways in axons of cultured sympathetic neurons. J. Neurosci. 16, 6056-6064 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 6056-6064
-
-
Overly, C.C.1
Hollenbeck, P.J.2
-
92
-
-
0028906375
-
Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine
-
Overly, C. C., Lee, K. D., Berthiaume, E. & Hollenbeck, P. J. Quantitative measurement of intraorganelle pH in the endosomal-lysosomal pathway in neurons by using ratiometric imaging with pyranine. Proc. Natl Acad. Sci. USA 92, 3156-3160 (1995).
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 3156-3160
-
-
Overly, C.C.1
Lee, K.D.2
Berthiaume, E.3
Hollenbeck, P.J.4
-
93
-
-
0031730287
-
Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis
-
Zapf-Colby, A. & Olefsky, J. M. Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. Endocrinology 139, 3232-3240 (1998).
-
(1998)
Endocrinology
, vol.139
, pp. 3232-3240
-
-
Zapf-Colby, A.1
Olefsky, J.M.2
-
94
-
-
0035256647
-
Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor
-
Yano, H. et al. Association of Trk neurotrophin receptors with components of the cytoplasmic dynein motor. J. Neurosci. 21, RC125 (2001).
-
(2001)
J. Neurosci.
, vol.21
-
-
Yano, H.1
-
95
-
-
0020322468
-
Binding, internalization, and retrograde transport of 1251-nerve growth factor in cultured rat sympathetic neurons
-
Claude, P., Hawrot, E., Dunis, D. A. & Campenot, R. B. Binding, internalization, and retrograde transport of 1251-nerve growth factor in cultured rat sympathetic neurons. J. Neurosci. 2, 431-442 (1982).
-
(1982)
J. Neurosci.
, vol.2
, pp. 431-442
-
-
Claude, P.1
Hawrot, E.2
Dunis, D.A.3
Campenot, R.B.4
-
96
-
-
0016438595
-
Retrograde axonal transport of nerve growth factor: Specificity and biological importance
-
Stoeckel, K. & Thoenen, H. Retrograde axonal transport of nerve growth factor: specificity and biological importance. Brain Res. 85, 337-341 (1975).
-
(1975)
Brain Res.
, vol.85
, pp. 337-341
-
-
Stoeckel, K.1
Thoenen, H.2
-
97
-
-
10544248585
-
Endocytosis of activated TrkA: Evidence that nerve growth factor induces formation of signaling endosomes
-
Grimes, M. L. et al. Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes. J. Neurosci. 16, 7950-7964 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 7950-7964
-
-
Grimes, M.L.1
-
98
-
-
0036787904
-
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
-
Wang, Y., Pennock, S., Chen, X. & Wang, Z. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol. Cell. Biol. 22, 7279-7290 (2002).
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7279-7290
-
-
Wang, Y.1
Pennock, S.2
Chen, X.3
Wang, Z.4
-
99
-
-
0032499282
-
Rap1 mediates sustained MAP kinase activation induced by nerve growth factor
-
York, R. D. et al. Rap1 mediates sustained MAP kinase activation induced by nerve growth factor. Nature 392, 622-626 (1998).
-
(1998)
Nature
, vol.392
, pp. 622-626
-
-
York, R.D.1
-
100
-
-
0034735517
-
Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a
-
Barbieri, M. A. et al. Epidermal growth factor and membrane trafficking. EGF receptor activation of endocytosis requires Rab5a. J. Cell Biol. 151, 539-550 (2000).
-
(2000)
J. Cell Biol.
, vol.151
, pp. 539-550
-
-
Barbieri, M.A.1
-
101
-
-
0034676451
-
The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5
-
Lanzetti, L. et al. The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5. Nature 408, 374-377 (2000).
-
(2000)
Nature
, vol.408
, pp. 374-377
-
-
Lanzetti, L.1
-
102
-
-
0035171352
-
Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex
-
Lippe, R., Miaczynska, M., Rybin, V, Runge, A. & Zerial, M. Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex. Mol. Biol. Cell 12, 2219-2228 (2001).
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2219-2228
-
-
Lippe, R.1
Miaczynska, M.2
Rybin, V.3
Runge, A.4
Zerial, M.5
-
103
-
-
1542283606
-
Alzheimer's disease and NGF signaling
-
Salehi, A., Delcroix, J. D. & Swaab, D. F. Alzheimer's disease and NGF signaling. J. Neural. Transm. 111, 323-345 (2004).
-
(2004)
J. Neural. Transm.
, vol.111
, pp. 323-345
-
-
Salehi, A.1
Delcroix, J.D.2
Swaab, D.F.3
-
104
-
-
2942591228
-
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
-
Cooper, J. D. et al. Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion. Proc. Natl Acad. Sci. USA 98, 10439-10444 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, pp. 10439-10444
-
-
Cooper, J.D.1
-
105
-
-
0033813571
-
Neurotrophic factors in Alzheimer's and Parkinson's disease brain
-
Siegel, G. J. & Chauhan, N. B. Neurotrophic factors in Alzheimer's and Parkinson's disease brain. Brain Res. Brain Res. Rev. 33, 199-227 (2000).
-
(2000)
Brain Res. Brain Res. Rev.
, vol.33
, pp. 199-227
-
-
Siegel, G.J.1
Chauhan, N.B.2
-
106
-
-
0029039162
-
Nerve growth factor in Alzheimer's disease: Defective retrograde transport to nucleus basalis
-
Mufson, E. J., Conner, J. M. & Kordower, J. H. Nerve growth factor in Alzheimer's disease: defective retrograde transport to nucleus basalis. Neuroreport 6, 1063-1066 (1995).
-
(1995)
Neuroreport
, vol.6
, pp. 1063-1066
-
-
Mufson, E.J.1
Conner, J.M.2
Kordower, J.H.3
-
107
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier, L. R. et al. Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118, 127-138 (2004).
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
-
108
-
-
0018309057
-
Independent control of the local environment of somas and neurites
-
Campenot, R. B. Independent control of the local environment of somas and neurites. Methods Enzymol. 58, 302-307 (1979).
-
(1979)
Methods Enzymol.
, vol.58
, pp. 302-307
-
-
Campenot, R.B.1
|