The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors

Current Biology

Volumn 11, Issue 21, 2001, Pages 1680-1685

  Jordens, Ingrid ^a   Fernandez Borja, Mar ^a   Marsman, Marije ^a   Dusseljee, Simone ^a   Janssen, Lennert ^a   Calafat, Jero ^a   Janssen, Hans ^a   Wubbolts, Richard ^a   Neefjes, Jacques ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035975946     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(01)00531-0     Document Type: Article

References (23)

1. Opposing motor activities of dynein and kinesin determine retention and transport of MHC class II-containing compartments
2. Regulated bidirectional motility of melanophore pigment granules along microtubules in vitro
3. Molecular requirements for bi-directional movement of phagosomes along microtubules
4. The involvement of the intermediate chain of cytoplasmic dynein in binding the motor complex to membranous organelles of Xenopus oocytes
5. The diversity of Rab proteins in vesicle transport
6. The Rab GTPase family
7. Rabinteracting lysosomal protein (RILP): The Rab7 effector required for transport to lysosomes
8. Rab7: A key to lysosome biogenesis
9. Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments
10. Rab 7: An important regulator of late endocytic membrane traffic
11. The rab7 GTPase resides on a vesicular compartment connected to lysosomes
12. Direct vesicular transport of MHC class II molecules from lysosomal structures to the cell surface
13. The major substrates for TAP in vivo are derived from newly synthesized proteins
14. RanBP1 is crucial for the release of RanGTP from importin beta-related nuclear transport factors
15. A brain serine/threonine protein kinase activated by Cdc42 and Rac1
16. PAK kinases are directly coupled to the PIX family of nucleotide exchange factors
17. Molecular characterization of the 50-kD subunit of dynactin reveals function for the complex in chromosome alignment and spindle organization during mitosis
18. Analysis of dynactin subcomplexes reveals a novel actin-related protein associated with the arp1 minifilament pointed end
19. Dynactin-dependent, dynein-driven vesicle transport in the absence of membrane proteins. A role for spectrin and acidic phospholipids
20. BetaIII spectrin binds to the Arp1 subunit of dynactin
21. Interaction of a Golgi-associated kinesin-like protein with Rab6
22. Rab5 regulates motility of early endosomes on microtubules
23. Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle