The Legs at odd angles (Loa) mutation in cytoplasmic dynein ameliorates mitochondrial function in SOD1G93A mouse model for motor neuron disease

Journal of Biological Chemistry

Volumn 285, Issue 24, 2010, Pages 18627-18639

  El Kadi, Ali Morsi ^a   Bros Facer, Virginie ^b   Deng, Wenhan ^a   Philpott, Amelia ^a   Stoddart, Eleanor ^a   Banks, Gareth ^b   Jackson, Graham S ^b   Fisher, Elizabeth M C ^b   Duchen, Michael R ^c   Greensmith, Linda ^b   Moore, Anthony L ^a   Hafezparast, Majid ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYOTROPHIC LATERAL SCLEROSIS; AUTOSOMAL DOMINANTS; CYTOPLASMIC DYNEIN; DIRECT INTERACTIONS; HEAVY CHAIN; LIFE SPAN; MEMBRANE POTENTIALS; MITOCHONDRIAL FUNCTION; MITOCHONDRIAL MATRIX; MITOCHONDRIAL RESPIRATION; MOTOR NEURON DISEASE; MOTOR NEURONS; MOUSE MODELS; NEURODEGENERATIVE DISEASE; SPINAL CORDS; SUPER OXIDE DISMUTASE; TOXIC EFFECT; TRANSGENIC MICE; WILD TYPES;

BRAIN; MITOCHONDRIA; OXYGEN; PROTEINS; TOXIC MATERIALS;

NEURONS;

COPPER ZINC SUPEROXIDE DISMUTASE; DYNEIN ADENOSINE TRIPHOSPHATASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE MUTATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOTONEURON; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CYTOPLASM; DISEASE MODELS, ANIMAL; DYNEINS; FEMALE; HETEROZYGOTE; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; MOTOR NEURON DISEASE; MOTOR NEURONS; MUTATION; SUPEROXIDE DISMUTASE;

MUS MUSCULUS;

EID: 77953309202     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.129320     Document Type: Article

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