-
1
-
-
1842334441
-
Anterograde transport of brain-derived neurotrophic factor and its role in the brain
-
Altar CA, Cai N, Bliven T, Juhasz M, Conner JM, Acheson AL, Lindsay RM, Wiegand SJ (1997) Anterograde transport of brain-derived neurotrophic factor and its role in the brain. Nature 389: 856-860
-
(1997)
Nature
, vol.389
, pp. 856-860
-
-
Altar, C.A.1
Cai, N.2
Bliven, T.3
Juhasz, M.4
Conner, J.M.5
Acheson, A.L.6
Lindsay, R.M.7
Wiegand, S.J.8
-
2
-
-
33947607769
-
The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport
-
Araki Y, Kawano T, Taru H, Saito Y, Wada S, Miyamoto K, Kobayashi H, Ishikawa HO, Ohsugi Y, Yamamoto T, Matsuno K, Kinjo M, Suzuki T (2007) The novel cargo Alcadein induces vesicle association of kinesin-1 motor components and activates axonal transport. EMBO J 26: 1475-1486
-
(2007)
EMBO J
, vol.26
, pp. 1475-1486
-
-
Araki, Y.1
Kawano, T.2
Taru, H.3
Saito, Y.4
Wada, S.5
Miyamoto, K.6
Kobayashi, H.7
Ishikawa, H.O.8
Ohsugi, Y.9
Yamamoto, T.10
Matsuno, K.11
Kinjo, M.12
Suzuki, T.13
-
3
-
-
0024805885
-
Changes in microtubule polarity orientation during the development of hippocampal neurons in culture
-
Baas PW, Black MM, Banker GA (1989) Changes in microtubule polarity orientation during the development of hippocampal neurons in culture. J Cell Biol 109: 3085-3094
-
(1989)
J Cell Biol
, vol.109
, pp. 3085-3094
-
-
Baas, P.W.1
Black, M.M.2
Banker, G.A.3
-
4
-
-
2442506955
-
Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor
-
Baquet ZC, Gorski JA, Jones KR (2004) Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor. J Neurosci 24: 4250-4258
-
(2004)
J Neurosci
, vol.24
, pp. 4250-4258
-
-
Baquet, Z.C.1
Gorski, J.A.2
Jones, K.R.3
-
5
-
-
0030878098
-
Fast transport and retrograde movement of huntingtin and HAP 1 in axons
-
Block-Galarza J, Chase KO, Sapp E, Vaughn KT, Vallee RB, DiFiglia M, Aronin N (1997) Fast transport and retrograde movement of huntingtin and HAP 1 in axons. NeuroReport 8: 2247-2251
-
(1997)
NeuroReport
, vol.8
, pp. 2247-2251
-
-
Block-Galarza, J.1
Chase, K.O.2
Sapp, E.3
Vaughn, K.T.4
Vallee, R.B.5
DiFiglia, M.6
Aronin, N.7
-
6
-
-
33751282353
-
Huntington's disease: From huntingtin function and dysfunction to therapeutic strategies
-
Borrell-Pages M, Zala D, Humbert S, Saudou F (2006) Huntington's disease: from huntingtin function and dysfunction to therapeutic strategies. Cell Mol Life Sci 63: 2642-2660
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 2642-2660
-
-
Borrell-Pages, M.1
Zala, D.2
Humbert, S.3
Saudou, F.4
-
7
-
-
0025021497
-
A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm
-
Brady ST, Pfister KK, Bloom GS (1990) A monoclonal antibody against kinesin inhibits both anterograde and retrograde fast axonal transport in squid axoplasm. Proc Natl Acad Sci USA 87: 1061-1065
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 1061-1065
-
-
Brady, S.T.1
Pfister, K.K.2
Bloom, G.S.3
-
8
-
-
0030727535
-
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution
-
Burkhardt JK, Echeverri CJ, Nilsson T, Vallee RB (1997) Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distribution. J Cell Biol 139: 469-484
-
(1997)
J Cell Biol
, vol.139
, pp. 469-484
-
-
Burkhardt, J.K.1
Echeverri, C.J.2
Nilsson, T.3
Vallee, R.B.4
-
9
-
-
34547193908
-
Huntingtin facilitates dynein/dynactin-mediated vesicle transport
-
Caviston JP, Ross JL, Antony SM, Tokito M, Holzbaur EL (2007) Huntingtin facilitates dynein/dynactin-mediated vesicle transport. Proc Natl Acad Sci USA 104: 10045-10050
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 10045-10050
-
-
Caviston, J.P.1
Ross, J.L.2
Antony, S.M.3
Tokito, M.4
Holzbaur, E.L.5
-
10
-
-
0037415607
-
Dynactin is required for bidirectional organelle transport
-
Deacon SW, Serpinskaya AS, Vaughan PS, Fanarraga ML, Vernos I, Vaughan KT, Gelfand VI (2003) Dynactin is required for bidirectional organelle transport. J Cell Biol 160: 297-300
-
(2003)
J Cell Biol
, vol.160
, pp. 297-300
-
-
Deacon, S.W.1
Serpinskaya, A.S.2
Vaughan, P.S.3
Fanarraga, M.L.4
Vernos, I.5
Vaughan, K.T.6
Gelfand, V.I.7
-
11
-
-
34047175919
-
Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation
-
Dompierre JP, Godin JD, Charrin BC, Cordelieres FP, King SJ, Humbert S, Saudou F (2007) Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation. J Neurosci 27: 3571-3583
-
(2007)
J Neurosci
, vol.27
, pp. 3571-3583
-
-
Dompierre, J.P.1
Godin, J.D.2
Charrin, B.C.3
Cordelieres, F.P.4
King, S.J.5
Humbert, S.6
Saudou, F.7
-
12
-
-
0034710696
-
A mutant of the motor protein kinesin that moves in both directions on microtubules
-
Endow SA, Higuchi H (2000) A mutant of the motor protein kinesin that moves in both directions on microtubules. Nature 406: 913-916
-
(2000)
Nature
, vol.406
, pp. 913-916
-
-
Endow, S.A.1
Higuchi, H.2
-
13
-
-
0030726894
-
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin
-
Engelender S, Sharp AH, Colomer V, Tokito MK, Lanahan A, Worley P, Holzbaur EL, Ross CA (1997) Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin. Hum Mol Genet 6: 2205-2212
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2205-2212
-
-
Engelender, S.1
Sharp, A.H.2
Colomer, V.3
Tokito, M.K.4
Lanahan, A.5
Worley, P.6
Holzbaur, E.L.7
Ross, C.A.8
-
14
-
-
3142636768
-
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules
-
Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, Cordelieres FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F (2004) Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules. Cell 118: 127-138
-
(2004)
Cell
, vol.118
, pp. 127-138
-
-
Gauthier, L.R.1
Charrin, B.C.2
Borrell-Pages, M.3
Dompierre, J.P.4
Rangone, H.5
Cordelieres, F.P.6
De Mey, J.7
MacDonald, M.E.8
Lessmann, V.9
Humbert, S.10
Saudou, F.11
-
15
-
-
33646768127
-
Axonal transport of mitochondria requires Milton to recruit kinesin heavy chain and is light chain independent
-
Glater EE, Megeath LJ, Stowers RS, Schwarz TL (2006) Axonal transport of mitochondria requires Milton to recruit kinesin heavy chain and is light chain independent. J Cell Biol 173: 545-557
-
(2006)
J Cell Biol
, vol.173
, pp. 545-557
-
-
Glater, E.E.1
Megeath, L.J.2
Stowers, R.S.3
Schwarz, T.L.4
-
16
-
-
0141503438
-
A determinant for directionality of organelle transport in Drosophila embryos
-
Gross SP, Guo Y, Martinez JE, Welte MA (2003) A determinant for directionality of organelle transport in Drosophila embryos. Curr Biol 13: 1660-1668
-
(2003)
Curr Biol
, vol.13
, pp. 1660-1668
-
-
Gross, S.P.1
Guo, Y.2
Martinez, J.E.3
Welte, M.A.4
-
17
-
-
0141750470
-
Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila
-
Gunawardena S, Her LS, Brusch RG, Laymon RA, Niesman IR, Gordesky-Gold B, Sintasath L, Bonini NM, Goldstein LS (2003) Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila. Neuron 40: 25-40
-
(2003)
Neuron
, vol.40
, pp. 25-40
-
-
Gunawardena, S.1
Her, L.S.2
Brusch, R.G.3
Laymon, R.A.4
Niesman, I.R.5
Gordesky-Gold, B.6
Sintasath, L.7
Bonini, N.M.8
Goldstein, L.S.9
-
18
-
-
0029152808
-
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies
-
Gutekunst CA, Levey AI, Heilman CJ, Whaley WL, Yi H, Nash NR, Rees HD, Madden JJ, Hersch SM (1995) Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies. Proc Natl Acad Sci USA 92: 8710-8714
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 8710-8714
-
-
Gutekunst, C.A.1
Levey, A.I.2
Heilman, C.J.3
Whaley, W.L.4
Yi, H.5
Nash, N.R.6
Rees, H.D.7
Madden, J.J.8
Hersch, S.M.9
-
19
-
-
30544452263
-
The axonal transport of mitochondria
-
Hollenbeck PJ, Saxton WM (2005) The axonal transport of mitochondria. J Cell Sci 118: 5411-5419
-
(2005)
J Cell Sci
, vol.118
, pp. 5411-5419
-
-
Hollenbeck, P.J.1
Saxton, W.M.2
-
20
-
-
0031947483
-
The role of the dynactin complex in intracellular motility
-
Holleran EA, Karki S, Holzbaur ELF (1998) The role of the dynactin complex in intracellular motility. Int Rev Cytol 182: 69-109
-
(1998)
Int Rev Cytol
, vol.182
, pp. 69-109
-
-
Holleran, E.A.1
Karki, S.2
Holzbaur, E.L.F.3
-
21
-
-
0036083379
-
The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt
-
Humbert S, Bryson EA, Cordelieres FP, Connors NC, Datta SR, Finkbeiner S, Greenberg ME, Saudou F (2002) The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt. Dev Cell 2: 831-837
-
(2002)
Dev Cell
, vol.2
, pp. 831-837
-
-
Humbert, S.1
Bryson, E.A.2
Cordelieres, F.P.3
Connors, N.C.4
Datta, S.R.5
Finkbeiner, S.6
Greenberg, M.E.7
Saudou, F.8
-
22
-
-
0034075589
-
Axonal membrane proteins are transported in distinct carriers: A two-color video microscopy study in cultured hippocampal neurons
-
Kaether C, Skehel P, Dotti CG (2000) Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons. Mol Biol Cell 11: 1213-1224
-
(2000)
Mol Biol Cell
, vol.11
, pp. 1213-1224
-
-
Kaether, C.1
Skehel, P.2
Dotti, C.G.3
-
23
-
-
0034279183
-
KIF5C, a novel neuronal kinesin enriched in motor neurons
-
Kanai Y, Okada Y, Tanaka Y, Harada A, Terada S, Hirokawa N (2000) KIF5C, a novel neuronal kinesin enriched in motor neurons. J Neurosci 20: 6374-6384
-
(2000)
J Neurosci
, vol.20
, pp. 6374-6384
-
-
Kanai, Y.1
Okada, Y.2
Tanaka, Y.3
Harada, A.4
Terada, S.5
Hirokawa, N.6
-
24
-
-
20344382542
-
Kinesin and dynein move a peroxisome in vivo: A tug-of-war or coordinated movement?
-
Kural C, Kim H, Syed S, Goshima G, Gelfand VI, Selvin PR (2005) Kinesin and dynein move a peroxisome in vivo: a tug-of-war or coordinated movement? Science 308: 1469-1472
-
(2005)
Science
, vol.308
, pp. 1469-1472
-
-
Kural, C.1
Kim, H.2
Syed, S.3
Goshima, G.4
Gelfand, V.I.5
Selvin, P.R.6
-
25
-
-
0032519646
-
Interaction of huntingtin-associated protein with dynactin P150Glued
-
Li SH, Gutekunst CA, Hersch SM, Li XJ (1998) Interaction of huntingtin-associated protein with dynactin P150Glued. J Neurosci 18: 1261-1269
-
(1998)
J Neurosci
, vol.18
, pp. 1261-1269
-
-
Li, S.H.1
Gutekunst, C.A.2
Hersch, S.M.3
Li, X.J.4
-
26
-
-
0028803757
-
A huntingtin-associated protein enriched in brain with implications for pathology
-
Li XJ, Li SH, Sharp AH, Nucifora Jr FC, Schilling G, Lanahan A, Worley P, Snyder SH, Ross CA (1995) A huntingtin-associated protein enriched in brain with implications for pathology. Nature 378: 398-402
-
(1995)
Nature
, vol.378
, pp. 398-402
-
-
Li, X.J.1
Li, S.H.2
Sharp, A.H.3
Nucifora Jr, F.C.4
Schilling, G.5
Lanahan, A.6
Worley, P.7
Snyder, S.H.8
Ross, C.A.9
-
27
-
-
2342640469
-
A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity
-
Ligon LA, Tokito M, Finklestein JM, Grossman FE, Holzbaur EL (2004) A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. J Biol Chem 279: 19201-19208
-
(2004)
J Biol Chem
, vol.279
, pp. 19201-19208
-
-
Ligon, L.A.1
Tokito, M.2
Finklestein, J.M.3
Grossman, F.E.4
Holzbaur, E.L.5
-
28
-
-
0032741064
-
Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport
-
Martin M, Iyadurai SJ, Gassman A, Gindhart Jr JG, Hays TS, Saxton WM (1999) Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport. Mol Biol Cell 10: 3717-3728
-
(1999)
Mol Biol Cell
, vol.10
, pp. 3717-3728
-
-
Martin, M.1
Iyadurai, S.J.2
Gassman, A.3
Gindhart Jr, J.G.4
Hays, T.S.5
Saxton, W.M.6
-
29
-
-
0034657922
-
Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth
-
Martinez-Arca S, Alberts P, Zahraoui A, Louvard D, Galli T (2000) Role of tetanus neurotoxin insensitive vesicle-associated membrane protein (TI-VAMP) in vesicular transport mediating neurite outgrowth. J Cell Biol 149: 889-900
-
(2000)
J Cell Biol
, vol.149
, pp. 889-900
-
-
Martinez-Arca, S.1
Alberts, P.2
Zahraoui, A.3
Louvard, D.4
Galli, T.5
-
30
-
-
33645642673
-
Interaction of Huntingtin-associated protein-1 with kinesin light chain: Implications in intracellular trafficking in neurons
-
McGuire JR, Rong J, Li SH, Li XJ (2006) Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons. J Biol Chem 281: 3552-3559
-
(2006)
J Biol Chem
, vol.281
, pp. 3552-3559
-
-
McGuire, J.R.1
Rong, J.2
Li, S.H.3
Li, X.J.4
-
31
-
-
32644434386
-
Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease
-
Pal A, Severin F, Lommer B, Shevchenko A, Zerial M (2006) Huntingtin-HAP40 complex is a novel Rab5 effector that regulates early endosome motility and is up-regulated in Huntington's disease. J Cell Biol 172: 605-618
-
(2006)
J Cell Biol
, vol.172
, pp. 605-618
-
-
Pal, A.1
Severin, F.2
Lommer, B.3
Shevchenko, A.4
Zerial, M.5
-
32
-
-
32544432052
-
Inhibition of calcineurin by FK506 protects against polyglutamine- huntingtin toxicity through an increase of huntingtin phosphorylation at S421
-
Pardo R, Colin E, Regulier E, Aebischer P, Deglon N, Humbert S, Saudou F (2006) Inhibition of calcineurin by FK506 protects against polyglutamine- huntingtin toxicity through an increase of huntingtin phosphorylation at S421. J Neurosci 26: 1635-1645
-
(2006)
J Neurosci
, vol.26
, pp. 1635-1645
-
-
Pardo, R.1
Colin, E.2
Regulier, E.3
Aebischer, P.4
Deglon, N.5
Humbert, S.6
Saudou, F.7
-
33
-
-
0032475931
-
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions
-
Saudou F, Finkbeiner S, Devys D, Greenberg ME (1998) Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions. Cell 95: 55-66
-
(1998)
Cell
, vol.95
, pp. 55-66
-
-
Saudou, F.1
Finkbeiner, S.2
Devys, D.3
Greenberg, M.E.4
-
35
-
-
0023754370
-
The role of kinesin and other soluble factors in organelle movement along microtubules
-
Schroer TA, Schnapp BJ, Reese TS, Sheetz MP (1988) The role of kinesin and other soluble factors in organelle movement along microtubules. J Cell Biol 107: 1785-1792
-
(1988)
J Cell Biol
, vol.107
, pp. 1785-1792
-
-
Schroer, T.A.1
Schnapp, B.J.2
Reese, T.S.3
Sheetz, M.P.4
-
36
-
-
0345701251
-
Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein)
-
Stepanova T, Slemmer J, Hoogenraad CC, Lansbergen G, Dortland B, De Zeeuw CI, Grosveld F, van Cappellen G, Akhmanova A, Galjart N (2003) Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein). J Neurosci 23: 2655-2664
-
(2003)
J Neurosci
, vol.23
, pp. 2655-2664
-
-
Stepanova, T.1
Slemmer, J.2
Hoogenraad, C.C.3
Lansbergen, G.4
Dortland, B.5
De Zeeuw, C.I.6
Grosveld, F.7
van Cappellen, G.8
Akhmanova, A.9
Galjart, N.10
-
37
-
-
17144365137
-
Neurotrophins: A ticket to ride for BDNF
-
Thomas K, Davies A (2005) Neurotrophins: a ticket to ride for BDNF. Curr Biol 15: R262-R264
-
(2005)
Curr Biol
, vol.15
-
-
Thomas, K.1
Davies, A.2
-
38
-
-
0037459061
-
The molecular motor toolbox for intracellular transport
-
Vale RD (2003) The molecular motor toolbox for intracellular transport. Cell 112: 467-480
-
(2003)
Cell
, vol.112
, pp. 467-480
-
-
Vale, R.D.1
-
39
-
-
0030716506
-
The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport
-
Waterman-Storer CM, Karki SB, Kuznetsov SA, Tabb JS, Weiss DG, Langford GM, Holzbaur EL (1997) The interaction between cytoplasmic dynein and dynactin is required for fast axonal transport. Proc Natl Acad Sci USA 94: 12180-12185
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12180-12185
-
-
Waterman-Storer, C.M.1
Karki, S.B.2
Kuznetsov, S.A.3
Tabb, J.S.4
Weiss, D.G.5
Langford, G.M.6
Holzbaur, E.L.7
-
40
-
-
3142642871
-
Bidirectional transport along microtubules
-
Welte MA (2004) Bidirectional transport along microtubules. Curr Biol 14: R525-R537
-
(2004)
Curr Biol
, vol.14
-
-
Welte, M.A.1
-
41
-
-
0032548920
-
Developmental regulation of vesicle transport in Drosophila embryos: Forces and kinetics
-
Welte MA, Gross SP, Postner M, Block SM, Wieschaus EF (1998) Developmental regulation of vesicle transport in Drosophila embryos: forces and kinetics. Cell 92: 547-557
-
(1998)
Cell
, vol.92
, pp. 547-557
-
-
Welte, M.A.1
Gross, S.P.2
Postner, M.3
Block, S.M.4
Wieschaus, E.F.5
-
42
-
-
0035919701
-
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
-
Zuccato C, Ciammola A, Rigamonti D, Leavitt BR, Goffredo D, Conti L, MacDonald ME, Friedlander RM, Silani V, Hayden MR, Timmusk T, Sipione S, Cattaneo E (2001) Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease. Science 293: 493-498
-
(2001)
Science
, vol.293
, pp. 493-498
-
-
Zuccato, C.1
Ciammola, A.2
Rigamonti, D.3
Leavitt, B.R.4
Goffredo, D.5
Conti, L.6
MacDonald, M.E.7
Friedlander, R.M.8
Silani, V.9
Hayden, M.R.10
Timmusk, T.11
Sipione, S.12
Cattaneo, E.13
|