NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits

Journal of Neuroscience

Volumn 29, Issue 45, 2009, Pages 14177-14184

  Weberpals, Marc ^a   Hermes, Michael ^a   Hermann, S ^b   Kummer, Markus P ^a   Terwel, Dick ^a   Semmler, Alexander ^a   Berger, Meike ^b   Schäfers, Michael ^b   Heneka, Michael T ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; BETA ACTIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; FLUORODEOXYGLUCOSE F 18; GLUCOSE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MUNC18 PROTEIN; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPTOBREVIN; SYNAPTOPHYSIN; SYNAPTOTAGMIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN METABOLISM; BRAIN PROTECTION; CELL ACTIVATION; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE SEVERITY; GENE; GENE EXPRESSION; GLUCOSE TRANSPORT; IMMUNOHISTOCHEMISTRY; LEARNING; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NONHUMAN; NOS2 GENE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; REFERENCE MEMORY; SEPSIS; WILD TYPE; WORKING MEMORY;

ANIMALS; BRAIN; CELL DEATH; COGNITION DISORDERS; GLUCOSE; LIPOPOLYSACCHARIDES; MAZE LEARNING; MEMORY, SHORT-TERM; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NITRIC OXIDE SYNTHASE TYPE II; RNA, MESSENGER; SEPSIS; SYNAPSES;

EID: 70449678686     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3238-09.2009     Document Type: Article

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