-
1
-
-
0033018506
-
Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis
-
G. Almer, S. Vukosavic, N. Romero, and S. Przedborski Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis J. Neurochem. 72 1999 2415 2425
-
(1999)
J. Neurochem.
, vol.72
, pp. 2415-2425
-
-
Almer, G.1
Vukosavic, S.2
Romero, N.3
Przedborski, S.4
-
2
-
-
0036326074
-
Protective action of the peroxisome proliferator-activated receptor-γ agonist pioglitazone in a mouse model of Parkinson's Disease
-
T. Breidert, J. Callebert, M.T. Heneka, G. Landreth, J.M. Launay, and E.C. Hirsch Protective action of the peroxisome proliferator-activated receptor-γ agonist pioglitazone in a mouse model of Parkinson's Disease J. Neurochem. 82 2002 615 624
-
(2002)
J. Neurochem.
, vol.82
, pp. 615-624
-
-
Breidert, T.1
Callebert, J.2
Heneka, M.T.3
Landreth, G.4
Launay, J.M.5
Hirsch, E.C.6
-
3
-
-
0028015713
-
Peroxisome proliferator-activated receptor (PPAR) gamma: Adipose-predominant expression and induction early in adipocyte differentiation
-
A. Chawla, E.J. Schwarz, D.D. Dimaculangan, and M.A. Lazar Peroxisome proliferator-activated receptor (PPAR) gamma: adipose-predominant expression and induction early in adipocyte differentiation Endocrinology 135 1994 798 800
-
(1994)
Endocrinology
, vol.135
, pp. 798-800
-
-
Chawla, A.1
Schwarz, E.J.2
Dimaculangan, D.D.3
Lazar, M.A.4
-
4
-
-
0032528350
-
Inhibition of inducible nitric oxide synthase by peroxisome proliferator-activated receptor agonists: Correlation with induction of heme oxygenase 1
-
P.R. Colville-Nash, S.S. Qureshi, D. Willis, and D.A. Willoughby Inhibition of inducible nitric oxide synthase by peroxisome proliferator- activated receptor agonists: correlation with induction of heme oxygenase 1 J. Immunol. 161 1998 978 984
-
(1998)
J. Immunol.
, vol.161
, pp. 978-984
-
-
Colville-Nash, P.R.1
Qureshi, S.S.2
Willis, D.3
Willoughby, D.A.4
-
5
-
-
0347087323
-
Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with Iκbα induction and block of NFκB and iNOS activation
-
T. Dehmer, M.T. Heneka, M. Sastre, J. Dichgans, and J.B. Schulz Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with Iκbα induction and block of NFκB and iNOS activation J. Neurochem. 88 2004 494 501
-
(2004)
J. Neurochem.
, vol.88
, pp. 494-501
-
-
Dehmer, T.1
Heneka, M.T.2
Sastre, M.3
Dichgans, J.4
Schulz, J.B.5
-
6
-
-
0035500386
-
Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis
-
J.L. Elliott Cytokine upregulation in a murine model of familial amyotrophic lateral sclerosis Brain Res. Mol. Brain Res. 95 2001 172 178
-
(2001)
Brain Res. Mol. Brain Res.
, vol.95
, pp. 172-178
-
-
Elliott, J.L.1
-
7
-
-
0036260784
-
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis
-
D.L. Feinstein, E. Galea, V. Gavrilyuk, C.F. Brosnan, C.C. Whitacre, L. Dumitrescu-Ozimek, G.E. Landreth, H.A. Pershadsingh, G. Weinberg, and M.T. Heneka Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis Ann. Neurol. 51 2002 694 702
-
(2002)
Ann. Neurol.
, vol.51
, pp. 694-702
-
-
Feinstein, D.L.1
Galea, E.2
Gavrilyuk, V.3
Brosnan, C.F.4
Whitacre, C.C.5
Dumitrescu-Ozimek, L.6
Landreth, G.E.7
Pershadsingh, H.A.8
Weinberg, G.9
Heneka, M.T.10
-
8
-
-
0032499257
-
Inhibition of ICE slows ALS in mice
-
R.M. Friedlander, R.H. Brown, V. Gagliardini, J. Wang, and J. Yuan Inhibition of ICE slows ALS in mice Nature 392 1998 560
-
(1998)
Nature
, vol.392
, pp. 560
-
-
Friedlander, R.M.1
Brown, R.H.2
Gagliardini, V.3
Wang, J.4
Yuan, J.5
-
9
-
-
0031841018
-
Tumor necrosis factor is increased in the spinal cord of an animal model of motor neuron degeneration
-
P. Ghezzi, R. Bernardini, R. Giuffrida, M. Bellomo, C. Manzoni, D. Comoletti, E. Di Santo, F. Beningi, and T. Mennini Tumor necrosis factor is increased in the spinal cord of an animal model of motor neuron degeneration Eur. Cytokine Network 9 1998 139 144
-
(1998)
Eur. Cytokine Network
, vol.9
, pp. 139-144
-
-
Ghezzi, P.1
Bernardini, R.2
Giuffrida, R.3
Bellomo, M.4
Manzoni, C.5
Comoletti, D.6
Di Santo, E.7
Beningi, F.8
Mennini, T.9
-
10
-
-
0033000906
-
Inducible cyclooxygenase may have anti-inflammatory properties
-
D.W. Gilroy, P.R. Colville-Nash, D. Willis, J. Chivers, M.J. Paul-Clark, and D.A. Willoughby Inducible cyclooxygenase may have anti-inflammatory properties Nat. Med. 5 1999 698 701
-
(1999)
Nat. Med.
, vol.5
, pp. 698-701
-
-
Gilroy, D.W.1
Colville-Nash, P.R.2
Willis, D.3
Chivers, J.4
Paul-Clark, M.J.5
Willoughby, D.A.6
-
11
-
-
0028125281
-
Transgenic-mouse model of amyotrophic lateral sclerosis
-
M.E. Gurney Transgenic-mouse model of amyotrophic lateral sclerosis N. Engl. J. Med. 331 1994 1721 1722
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1721-1722
-
-
Gurney, M.E.1
-
12
-
-
0032125587
-
Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS
-
E.D. Hall, J.A. Oostveen, and M.E. Gurney Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS Glia 23 1998 249 256
-
(1998)
Glia
, vol.23
, pp. 249-256
-
-
Hall, E.D.1
Oostveen, J.A.2
Gurney, M.E.3
-
13
-
-
0033378706
-
Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine induced apoptotic cell death by inhibition of inducible nitric oxide synthase
-
M.T. Heneka, D.L. Feinstein, E. Galea, M. Gleichmann, U. Wullner, and T. Klockgether Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine induced apoptotic cell death by inhibition of inducible nitric oxide synthase J. Neuroimmunol. 100 1999 156 168
-
(1999)
J. Neuroimmunol.
, vol.100
, pp. 156-168
-
-
Heneka, M.T.1
Feinstein, D.L.2
Galea, E.3
Gleichmann, M.4
Wullner, U.5
Klockgether, T.6
-
14
-
-
0034666289
-
Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase and cell death in vivo
-
M.T. Heneka, T. Klockgether, and D.L. Feinstein Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase and cell death in vivo J. Neurosci. 20 2000 6862 6867
-
(2000)
J. Neurosci.
, vol.20
, pp. 6862-6867
-
-
Heneka, M.T.1
Klockgether, T.2
Feinstein, D.L.3
-
15
-
-
0036062628
-
Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93-SOD1 mouse model of amyotrophic lateral sclerosis
-
K. Hensley, R.A. Floyd, B. Gordon, S. Mou, Q.N. Pye, C. Stewart, M. West, and K. Williamson Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93-SOD1 mouse model of amyotrophic lateral sclerosis J. Neurochem. 82 2002 365 374
-
(2002)
J. Neurochem.
, vol.82
, pp. 365-374
-
-
Hensley, K.1
Floyd, R.A.2
Gordon, B.3
Mou, S.4
Pye, Q.N.5
Stewart, C.6
West, M.7
Williamson, K.8
-
16
-
-
0029838035
-
Neuropathology of ALS: An overview
-
A. Hirano Neuropathology of ALS: an overview Neurology 47 1996 S63 S66
-
(1996)
Neurology
, vol.47
-
-
Hirano, A.1
-
17
-
-
0031888958
-
PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines
-
C. Jiang, A.T. Ting, and B. Seed PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines Nature 391 1998 82 86
-
(1998)
Nature
, vol.391
, pp. 82-86
-
-
Jiang, C.1
Ting, A.T.2
Seed, B.3
-
18
-
-
0037311051
-
Effects of peroxisome proliferator-activated receptor-γ agonists on central nervous system inflammation
-
T. Kielian, and P.D. Drew Effects of peroxisome proliferator-activated receptor-γ agonists on central nervous system inflammation J. Neurosci. Res. 71 2003 315 325
-
(2003)
J. Neurosci. Res.
, vol.71
, pp. 315-325
-
-
Kielian, T.1
Drew, P.D.2
-
19
-
-
0034647003
-
Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model
-
M. Li, V.O. Ona, C. Guegan, M. Chen, V. Jackson-Lewis, L.J. Andrews, A.J. Olszweski, P.E. Stieg, J.P. Lee, S. Przedborski, and R.M. Friedlander Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model Science 288 2000 335 339
-
(2000)
Science
, vol.288
, pp. 335-339
-
-
Li, M.1
Ona, V.O.2
Guegan, C.3
Chen, M.4
Jackson-Lewis, V.5
Andrews, L.J.6
Olszweski, A.J.7
Stieg, P.E.8
Lee, J.P.9
Przedborski, S.10
Friedlander, R.M.11
-
20
-
-
0031057599
-
Disposition of the new antidiabetic agent pioglitazone in rats, dogs and monkeys
-
Y. Maeshiba, Y. Kiyota, K. Yamashita, Y. Yoshimura, M. Motohashi, and S. Tanayma Disposition of the new antidiabetic agent pioglitazone in rats, dogs and monkeys Arzneimittel-forschung 47 1997 29 35
-
(1997)
Arzneimittel-forschung
, vol.47
, pp. 29-35
-
-
Maeshiba, Y.1
Kiyota, Y.2
Yamashita, K.3
Yoshimura, Y.4
Motohashi, M.5
Tanayma, S.6
-
21
-
-
0031993322
-
Terminal differentiation of human breast cancer through PPAR gamma
-
E. Mueller, P. Sarraf, P. Tontonoz, R.M. Evans, K.J. Martin, M. Zhang, C. Fletcher, S. Singer, and B.M. Spiegelman Terminal differentiation of human breast cancer through PPAR gamma Mol. Cell. 1 1998 465 470
-
(1998)
Mol. Cell.
, vol.1
, pp. 465-470
-
-
Mueller, E.1
Sarraf, P.2
Tontonoz, P.3
Evans, R.M.4
Martin, K.J.5
Zhang, M.6
Fletcher, C.7
Singer, S.8
Spiegelman, B.M.9
-
22
-
-
0034765498
-
Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: No requirement for proapoptotic interleukin-1beta in neurodegeneration
-
M.D. Nguyen, J.P. Julien, and S. Rivest Induction of proinflammatory molecules in mice with amyotrophic lateral sclerosis: no requirement for proapoptotic interleukin-1beta in neurodegeneration Ann. Neurol. 50 2001 630 639
-
(2001)
Ann. Neurol.
, vol.50
, pp. 630-639
-
-
Nguyen, M.D.1
Julien, J.P.2
Rivest, S.3
-
23
-
-
0035194691
-
Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord
-
M.K. Olsen, S.L. Roberds, B.R. Ellerbrock, T.J. Fleck, D.K. McKinley, and M.E. Gurney Disease mechanisms revealed by transcription profiling in SOD1-G93A transgenic mouse spinal cord Ann. Neurol. 50 2001 730 740
-
(2001)
Ann. Neurol.
, vol.50
, pp. 730-740
-
-
Olsen, M.K.1
Roberds, S.L.2
Ellerbrock, B.R.3
Fleck, T.J.4
McKinley, D.K.5
Gurney, M.E.6
-
24
-
-
4344640378
-
Effect of pioglitazone treatment in a patient with secondary multiple sclerosis
-
H.A. Pershadsingh, M.T. Heneka, R. Saini, N.M. Amin, D.J. Broeske, and D.L. Feinstein Effect of pioglitazone treatment in a patient with secondary multiple sclerosis J. Neuroinflammation 20 1 (1) 2004 3
-
(2004)
J. Neuroinflammation
, vol.20
, Issue.11
, pp. 3
-
-
Pershadsingh, H.A.1
Heneka, M.T.2
Saini, R.3
Amin, N.M.4
Broeske, D.J.5
Feinstein, D.L.6
-
25
-
-
0033551134
-
Cyclopentenone prostaglandins suppress activation of microglia: Down-regulation of inducible nitric oxide synthase by 15-deoxy-Delta 12, 14-prostaglandin J2
-
T.V. Petrova, K.T. Akama, and L.J. Van Eldik Cyclopentenone prostaglandins suppress activation of microglia: down-regulation of inducible nitric oxide synthase by 15-deoxy-Delta 12, 14-prostaglandin J2 Proc. Natl. Acad. Sci. U. S. A. 96 1999 4668 4673
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 4668-4673
-
-
Petrova, T.V.1
Akama, K.T.2
Van Eldik, L.J.3
-
26
-
-
0031886864
-
The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation
-
M. Ricote, A.C. Li, T.M. Wilson, C.J. Kelly, and C.K. Glass The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation Nature 391 1998 79 82
-
(1998)
Nature
, vol.391
, pp. 79-82
-
-
Ricote, M.1
Li, A.C.2
Wilson, T.M.3
Kelly, C.J.4
Glass, C.K.5
-
27
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
D.R. Rosen, T. Siddique, and D. Patterson Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis Nature 362 1993 59 62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
-
28
-
-
0029812020
-
Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis
-
D. Schiffer, S. Cordera, P. Cavalla, and A. Migheli Reactive astrogliosis of the spinal cord in amyotrophic lateral sclerosis J. Neurol. Sci. 139 Suppl. 1996 27 33
-
(1996)
J. Neurol. Sci.
, vol.139
, pp. 27-33
-
-
Schiffer, D.1
Cordera, S.2
Cavalla, P.3
Migheli, A.4
-
29
-
-
0028180070
-
MPPAR gamma 2: Tissue-specific regulator of an adipocyte enhancer
-
P. Tontonoz, E. Hu, R.A. Graves, A.I. Budavari, and B.M. Spiegelman mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer Genes Dev. 8 1994 1224 1234
-
(1994)
Genes Dev.
, vol.8
, pp. 1224-1234
-
-
Tontonoz, P.1
Hu, E.2
Graves, R.A.3
Budavari, A.I.4
Spiegelman, B.M.5
-
30
-
-
0026339976
-
Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
-
M.J. West, L. Slomianka, and H.J. Gundersen Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator Anat. Rec. 231 1991 482 497
-
(1991)
Anat. Rec.
, vol.231
, pp. 482-497
-
-
West, M.J.1
Slomianka, L.2
Gundersen, H.J.3
-
31
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
P.C. Wong, C.A. Pardo, D.R. Borchelt, M.K. Lee, N.G. Copeland, N.A. Jenkins, S.S. Sisodia, D.W. Cleveland, and D.L. Price An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria Neuron 14 1995 1105 1116
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
Sisodia, S.S.7
Cleveland, D.W.8
Price, D.L.9
-
32
-
-
0036269810
-
Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis
-
T. Yoshihara, S. Ishigaki, M. Yamamoto, Y. Liang, J. Niwa, H. Takeuchi, M. Doyu, and G. Sobue Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis J. Neurochem. 80 2002 158 167
-
(2002)
J. Neurochem.
, vol.80
, pp. 158-167
-
-
Yoshihara, T.1
Ishigaki, S.2
Yamamoto, M.3
Liang, Y.4
Niwa, J.5
Takeuchi, H.6
Doyu, M.7
Sobue, G.8
-
33
-
-
4644269605
-
Role of peroxisome proliferator-activated receptors in inflammation control
-
J. Youssef, and M. Badr Role of peroxisome proliferator-activated receptors in inflammation control J. Biomed. Biotechnol. 3 2004 156 166
-
(2004)
J. Biomed. Biotechnol.
, vol.3
, pp. 156-166
-
-
Youssef, J.1
Badr, M.2
|