Fibrillar amyloid-β peptides activate microglia via TLR2: Implications for Alzheimer's disease

Journal of Immunology

Volumn 181, Issue 10, 2008, Pages 7254-7262

  Jana, Malabendu ^a   Palencia, Carlos A ^a   Pahan, Kalipada ^a  

^a RUSH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CD11B ANTIGEN; CD68 ANTIGEN; FIBRILLARIN; GLYCOPROTEIN P 15095; INTEGRIN; MYELOID DIFFERENTIATION FACTOR 88; TOLL LIKE RECEPTOR 2; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); CYTOKINE; LEUKOCYTE ANTIGEN; MESSENGER RNA; PEPTIDE FRAGMENT; TLR2 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; CELL ACTIVATION; CONTROLLED STUDY; ENZYME ACTIVATION; IN VIVO STUDY; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE EXPRESSION PROFILING; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; ANTIGENS, CD; CYTOKINES; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; GENE EXPRESSION PROFILING; MICE; MICE, KNOCKOUT; MICROGLIA; MYELOID DIFFERENTIATION FACTOR 88; PEPTIDE FRAGMENTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOLL-LIKE RECEPTOR 2;

EID: 58149181978     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.10.7254     Document Type: Article

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