Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease

Journal of Neuroscience

Volumn 25, Issue 39, 2005, Pages 8843-8853

  Kitazawa, Masashi ^a   Oddo, Salvatore ^a   Yamasaki, Tritia R ^a   Green, Kim N ^a   LaFerla, Frank M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyloid; APP; cdk5; Interleukin; Microglia; Tau; Transgenic

Indexed keywords

AMYLOID BETA PROTEIN; CYCLIN DEPENDENT KINASE 5; LIPOPOLYSACCHARIDE; ROSCOVITINE; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ACTIVITY; DISEASE COURSE; DISEASE EXACERBATION; ENCEPHALITIS; FEMALE; HIPPOCAMPUS; MALE; MICROGLIA; MOUSE; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SENILE PLAQUE; TRANSGENIC MOUSE;

AGING; ALZHEIMER DISEASE; ANIMALS; CYCLIN-DEPENDENT KINASE 5; DISEASE MODELS, ANIMAL; ENCEPHALITIS; ENZYME ACTIVATION; FEMALE; HIPPOCAMPUS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, TRANSGENIC; MICROGLIA; NEURAL PATHWAYS; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PURINES; TAU PROTEINS; TAUOPATHIES;

EID: 25644456097     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2868-05.2005     Document Type: Article

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