메뉴 건너뛰기




Volumn 351, Issue 11, 2004, Pages

Thiazolidinediones

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ADIPONECTIN; ALBUMIN; ANTIRETROVIRUS AGENT; BIOLOGICAL MARKER; CHOLESTEROL; CLOMIFENE; CREATININE; FENOFIBRATE; GEMFIBROZIL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; PLACEBO; PLASMINOGEN ACTIVATOR INHIBITOR 1; RALOXIFENE; ROSIGLITAZONE; SULFONYLUREA DERIVATIVE; TAMOXIFEN; TRIACYLGLYCEROL; TROGLITAZONE; TYROSINE DERIVATIVE;

EID: 19244365650     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMra041001     Document Type: Review
Times cited : (1979)

References (120)
  • 1
    • 0028063888 scopus 로고
    • Pathogenesis of non-insulin-dependent diabetes mellitus
    • Yki-Järvinen H. Pathogenesis of non-insulin-dependent diabetes mellitus. Lancet 1994;343:91-5.
    • (1994) Lancet , vol.343 , pp. 91-95
    • Yki-Järvinen, H.1
  • 2
    • 0037034257 scopus 로고    scopus 로고
    • Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
    • Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med 2002;346:393-403.
    • (2002) N Engl J Med , vol.346 , pp. 393-403
  • 3
    • 4444384467 scopus 로고    scopus 로고
    • Insulin resistance in type 2 diabetes
    • Pickup JC, Williams G, eds. Oxford, England: Blackwell
    • Yki-Järvinen H. Insulin resistance in type 2 diabetes. In: Pickup JC, Williams G, eds. Textbook of diabetes. 3rd ed. Oxford, England: Blackwell, 2003:22.1-22.19.
    • (2003) Textbook of Diabetes. 3rd Ed.
    • Yki-Järvinen, H.1
  • 4
    • 0029016829 scopus 로고
    • An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)
    • Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma). J Biol Chem 1995;270:12953-6.
    • (1995) J Biol Chem , vol.270 , pp. 12953-12956
    • Lehmann, J.M.1    Moore, L.B.2    Smith-Oliver, T.A.3    Wilkison, W.O.4    Willson, T.M.5    Kliewer, S.A.6
  • 5
    • 0035976638 scopus 로고    scopus 로고
    • Nuclear receptors and lipid physiology: Opening the X-files
    • Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files. Science 2001;294: 1866-70.
    • (2001) Science , vol.294 , pp. 1866-1870
    • Chawla, A.1    Repa, J.J.2    Evans, R.M.3    Mangelsdorf, D.J.4
  • 6
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J, Moller DE. The mechanisms of action of PPARs. Annu Rev Med 2002;53: 409-35.
    • (2002) Annu Rev Med , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 7
    • 0036094913 scopus 로고    scopus 로고
    • Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis
    • Barbier O, Torra LP, Duguay Y, et al. Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis. Arterioscler Thromb Vasc Biol 2002;22:717-26.
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 717-726
    • Barbier, O.1    Torra, L.P.2    Duguay, Y.3
  • 8
    • 0034923501 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma and metabolic disease
    • Willson TM, Lambert MH, Kliewer SA. Peroxisome proliferator-activated receptor gamma and metabolic disease. Annu Rev Biochem 2001;70:341-67.
    • (2001) Annu Rev Biochem , vol.70 , pp. 341-367
    • Willson, T.M.1    Lambert, M.H.2    Kliewer, S.A.3
  • 9
    • 0033793133 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs): Nuclear receptors at the crossroads between lipid metabolism and inflammation
    • Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res 2000;49:497-505.
    • (2000) Inflamm Res , vol.49 , pp. 497-505
    • Chinetti, G.1    Fruchart, J.C.2    Staels, B.3
  • 10
    • 12444273748 scopus 로고    scopus 로고
    • Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator
    • Berger JP, Petro AE, Macnaul KL, et al. Distinct properties and advantages of a novel peroxisome proliferator-activated protein [gamma] selective modulator. Mol Endocrinol 2003;17:662-76.
    • (2003) Mol Endocrinol , vol.17 , pp. 662-676
    • Berger, J.P.1    Petro, A.E.2    Macnaul, K.L.3
  • 11
    • 0036399805 scopus 로고    scopus 로고
    • PPAR(gamma) and glucose homeostasis
    • Picard F, Auwerx J. PPAR(gamma) and glucose homeostasis. Annu Rev Nutr 2002; 22:167-97.
    • (2002) Annu Rev Nutr , vol.22 , pp. 167-197
    • Picard, F.1    Auwerx, J.2
  • 12
    • 2242436246 scopus 로고    scopus 로고
    • Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice
    • Duez H, Chao YS, Hernandez M, et al. Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice. J Biol Chem 2002;277:48051-7.
    • (2002) J Biol Chem , vol.277 , pp. 48051-48057
    • Duez, H.1    Chao, Y.S.2    Hernandez, M.3
  • 13
    • 0033527030 scopus 로고    scopus 로고
    • Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol
    • Rubins HB, Robins SJ, Collins D, et al. Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. N Engl J Med 1999;341:410-8.
    • (1999) N Engl J Med , vol.341 , pp. 410-418
    • Rubins, H.B.1    Robins, S.J.2    Collins, D.3
  • 14
    • 0035941990 scopus 로고    scopus 로고
    • Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: The Diabetes Atherosclerosis Intervention Study, a randomised study
    • Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet 2001; 357:905-10. [Erratum, Lancet 2001;357: 1890.]
    • (2001) Lancet , vol.357 , pp. 905-910
  • 15
    • 0035832505 scopus 로고    scopus 로고
    • Erratum
    • Effect of fenofibrate on progression of coronary-artery disease in type 2 diabetes: the Diabetes Atherosclerosis Intervention Study, a randomised study. Lancet 2001; 357:905-10. [Erratum, Lancet 2001;357: 1890.]
    • (2001) Lancet , vol.357 , pp. 1890
  • 16
    • 0037396839 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors beta/delta: Emerging roles for a previously neglected third family member
    • Michalik L, Desvergne B, Wahli W. Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member. Curr Opin Lipidol 2003;14:129-35.
    • (2003) Curr Opin Lipidol , vol.14 , pp. 129-135
    • Michalik, L.1    Desvergne, B.2    Wahli, W.3
  • 17
    • 0033811933 scopus 로고    scopus 로고
    • Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in normal human pancreatic islet cells
    • Dubois M, Pattou F, Kerr-Conte J, et al. Expression of peroxisome proliferator-activated receptor gamma (PPARgamma) in normal human pancreatic islet cells. Diabetologia 2000;43:1165-9.
    • (2000) Diabetologia , vol.43 , pp. 1165-1169
    • Dubois, M.1    Pattou, F.2    Kerr-Conte, J.3
  • 18
    • 0033754530 scopus 로고    scopus 로고
    • Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: A 6-month randomized placebo-controlled dose-response study
    • Aronoff S, Rosenblatt S, Braithwaite S, Egan JW, Mathisen AL, Schneider RL. Pioglitazone hydrochloride monotherapy improves glycemic control in the treatment of patients with type 2 diabetes: a 6-month randomized placebo-controlled dose-response study. Diabetes Care 2000;23:1605-11.
    • (2000) Diabetes Care , vol.23 , pp. 1605-1611
    • Aronoff, S.1    Rosenblatt, S.2    Braithwaite, S.3    Egan, J.W.4    Mathisen, A.L.5    Schneider, R.L.6
  • 19
    • 18744401592 scopus 로고    scopus 로고
    • Metabolic efficacy and safety of once-daily pioglitazone monotherapy in patients with type 2 diabetes: A double-blind, placebo-controlled study
    • Scherbaum WA, Göke B. Metabolic efficacy and safety of once-daily pioglitazone monotherapy in patients with type 2 diabetes: a double-blind, placebo-controlled study. Horm Metab Res 2002;34:589-95.
    • (2002) Horm Metab Res , vol.34 , pp. 589-595
    • Scherbaum, W.A.1    Göke, B.2
  • 20
    • 0034919411 scopus 로고    scopus 로고
    • The impact of pioglitazone on glycemic control and atherogenic dyslipidemia in patients with type 2 diabetes mellitus
    • Rosenblatt S, Miskin B, Glazer NB, Prince MJ, Robertson KE. The impact of pioglitazone on glycemic control and atherogenic dyslipidemia in patients with type 2 diabetes mellitus. Coron Artery Dis 2001;12: 413-23.
    • (2001) Coron Artery Dis , vol.12 , pp. 413-423
    • Rosenblatt, S.1    Miskin, B.2    Glazer, N.B.3    Prince, M.J.4    Robertson, K.E.5
  • 21
    • 0034531195 scopus 로고    scopus 로고
    • Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: A randomized, placebo-controlled study
    • Einhorn D, Rendell M, Rosenzweig J, Egan JW, Mathisen AL, Schneider RL. Pioglitazone hydrochloride in combination with metformin in the treatment of type 2 diabetes mellitus: a randomized, placebo-controlled study. Clin Ther 2000;22:1395-409.
    • (2000) Clin Ther , vol.22 , pp. 1395-1409
    • Einhorn, D.1    Rendell, M.2    Rosenzweig, J.3    Egan, J.W.4    Mathisen, A.L.5    Schneider, R.L.6
  • 22
    • 0034933056 scopus 로고    scopus 로고
    • Pioglitazone hydrochloride in combination with sulfonylurea therapy improves glycemic control in patients with type 2 diabetes mellitus: A randomized, placebo-controlled study
    • Kipnes MS, Krosnick A, Rendell MS, Egan JW, Mathisen AL, Schneider RL. Pioglitazone hydrochloride in combination with sulfonylurea therapy improves glycemic control in patients with type 2 diabetes mellitus: a randomized, placebo-controlled study. Am J Med 2001;111:10-7.
    • (2001) Am J Med , vol.111 , pp. 10-17
    • Kipnes, M.S.1    Krosnick, A.2    Rendell, M.S.3    Egan, J.W.4    Mathisen, A.L.5    Schneider, R.L.6
  • 23
    • 0036284873 scopus 로고    scopus 로고
    • Efficacy and safety of pioglitazone in type 2 diabetes: A randomised, placebo-controlled study in patients receiving stable insulin therapy
    • Rosenstock J, Einhorn D, Hershon K, Glazer NB, Yu S. Efficacy and safety of pioglitazone in type 2 diabetes: a randomised, placebo-controlled study in patients receiving stable insulin therapy. Int J Clin Pract 2002;56:251-7.
    • (2002) Int J Clin Pract , vol.56 , pp. 251-257
    • Rosenstock, J.1    Einhorn, D.2    Hershon, K.3    Glazer, N.B.4    Yu, S.5
  • 24
    • 0035140430 scopus 로고    scopus 로고
    • Rosiglitazone monotherapy is effective in patients with type 2 diabetes
    • Lebovitz HE, Dole JF, Parwardhan R, Rappaport EB, Freed MI. Rosiglitazone monotherapy is effective in patients with type 2 diabetes. J Clin Endocrinol Metab 2001;86:280-8. [Errata, J Clin Endocrinol Metab 2001;86:1659, 2002;87:iv.]
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 280-288
    • Lebovitz, H.E.1    Dole, J.F.2    Parwardhan, R.3    Rappaport, E.B.4    Freed, M.I.5
  • 25
    • 0035030226 scopus 로고    scopus 로고
    • Errata
    • Lebovitz HE, Dole JF, Parwardhan R, Rappaport EB, Freed MI. Rosiglitazone monotherapy is effective in patients with type 2 diabetes. J Clin Endocrinol Metab 2001;86:280-8. [Errata, J Clin Endocrinol Metab 2001;86:1659, 2002;87:iv.]
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1659
  • 26
    • 0035140430 scopus 로고    scopus 로고
    • Lebovitz HE, Dole JF, Parwardhan R, Rappaport EB, Freed MI. Rosiglitazone monotherapy is effective in patients with type 2 diabetes. J Clin Endocrinol Metab 2001;86:280-8. [Errata, J Clin Endocrinol Metab 2001;86:1659, 2002;87:iv.]
    • (2002) J Clin Endocrinol Metab , vol.87
  • 27
    • 0034607438 scopus 로고    scopus 로고
    • Effect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitus: A randomized controlled trial
    • Fonseca V, Rosenstock J, Patwardhan R, Salzman A. Effect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitus: a randomized controlled trial. JAMA 2000;283:1695-702. [Erratum, JAMA 2000;284:1384.]
    • (2000) JAMA , vol.283 , pp. 1695-1702
    • Fonseca, V.1    Rosenstock, J.2    Patwardhan, R.3    Salzman, A.4
  • 28
    • 85136353998 scopus 로고    scopus 로고
    • Erratum
    • Fonseca V, Rosenstock J, Patwardhan R, Salzman A. Effect of metformin and rosiglitazone combination therapy in patients with type 2 diabetes mellitus: a randomized controlled trial. JAMA 2000;283:1695-702. [Erratum, JAMA 2000;284:1384.]
    • (2000) JAMA , vol.284 , pp. 1384
  • 29
    • 0036244970 scopus 로고    scopus 로고
    • Efficacy and safety of rosiglitazone plus metformin in Mexicans with type 2 diabetes
    • Gomez-Perez FJ, Fanghanel-Salmon G, Antonio Barbosa J, et al. Efficacy and safety of rosiglitazone plus metformin in Mexicans with type 2 diabetes. Diabetes Metab Res Rev 2002;18:127-34.
    • (2002) Diabetes Metab Res Rev , vol.18 , pp. 127-134
    • Gomez-Perez, F.J.1    Fanghanel-Salmon, G.2    Antonio Barbosa, J.3
  • 30
    • 0036965689 scopus 로고    scopus 로고
    • An international study of the effects of rosiglitazone plus sulphonylurea in patients with type 2 diabetes
    • Vongthavaravat V, Wajchenberg BL, Waitman JN, et al. An international study of the effects of rosiglitazone plus sulphonylurea in patients with type 2 diabetes. Curr Med Res Opin 2002;18:456-61.
    • (2002) Curr Med Res Opin , vol.18 , pp. 456-461
    • Vongthavaravat, V.1    Wajchenberg, B.L.2    Waitman, J.N.3
  • 31
    • 0035408779 scopus 로고    scopus 로고
    • A randomized trial of rosiglitazone therapy in patients with inadequately controlled insulin-treated type 2 diabetes
    • Raskin P, Rendell M, Riddle MC, Dole JF, Freed MI, Rosenstock J. A randomized trial of rosiglitazone therapy in patients with inadequately controlled insulin-treated type 2 diabetes. Diabetes Care 2001;24:1226-32.
    • (2001) Diabetes Care , vol.24 , pp. 1226-1232
    • Raskin, P.1    Rendell, M.2    Riddle, M.C.3    Dole, J.F.4    Freed, M.I.5    Rosenstock, J.6
  • 32
    • 0027983920 scopus 로고
    • Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone
    • Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 1994;331:1188-93.
    • (1994) N Engl J Med , vol.331 , pp. 1188-1193
    • Nolan, J.J.1    Ludvik, B.2    Beerdsen, P.3    Joyce, M.4    Olefsky, J.5
  • 34
    • 0035671770 scopus 로고    scopus 로고
    • Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type 2 diabetic patients
    • Miyazaki Y, Glass L, Triplitt C, et al. Effect of rosiglitazone on glucose and non-esterified fatty acid metabolism in Type 2 diabetic patients. Diabetologia 2001;44: 2210-9.
    • (2001) Diabetologia , vol.44 , pp. 2210-2219
    • Miyazaki, Y.1    Glass, L.2    Triplitt, C.3
  • 35
    • 0842313004 scopus 로고    scopus 로고
    • Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients
    • Bajaj M, Suraamomkul S, Piper P, et al. Decreased plasma adiponectin concentrations are closely related to hepatic fat content and hepatic insulin resistance in pioglitazone-treated type 2 diabetic patients. J Clin Endocrinol Metab 2004;89:200-6.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 200-206
    • Bajaj, M.1    Suraamomkul, S.2    Piper, P.3
  • 36
    • 0036072223 scopus 로고    scopus 로고
    • Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients
    • Miyazaki Y, Mahankali A, Matsuda M, et al. Effect of pioglitazone on abdominal fat distribution and insulin sensitivity in type 2 diabetic patients. J Clin Endocrinol Metab 2002;87:2784-91.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2784-2791
    • Miyazaki, Y.1    Mahankali, A.2    Matsuda, M.3
  • 37
    • 0034833667 scopus 로고    scopus 로고
    • Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone
    • Miyazaki Y, Mahankali A, Matsuda M, et al. Improved glycemic control and enhanced insulin sensitivity in type 2 diabetic subjects treated with pioglitazone. Diabetes Care 2001;24:710-9.
    • (2001) Diabetes Care , vol.24 , pp. 710-719
    • Miyazaki, Y.1    Mahankali, A.2    Matsuda, M.3
  • 38
    • 0031977203 scopus 로고    scopus 로고
    • Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance: Effects of troglitazone
    • Tack CJ, Ong MK, Lutterman JA, Smits P. Insulin-induced vasodilatation and endothelial function in obesity/insulin resistance: effects of troglitazone. Diabetologia 1998;41:569-76.
    • (1998) Diabetologia , vol.41 , pp. 569-576
    • Tack, C.J.1    Ong, M.K.2    Lutterman, J.A.3    Smits, P.4
  • 39
    • 0030762562 scopus 로고    scopus 로고
    • Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance
    • Cavaghan MK, Ehrmann DA, Byrne MM, Polonsky KS. Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance. J Clin Invest 1997;100:530-7.
    • (1997) J Clin Invest , vol.100 , pp. 530-537
    • Cavaghan, M.K.1    Ehrmann, D.A.2    Byrne, M.M.3    Polonsky, K.S.4
  • 40
    • 0036517099 scopus 로고    scopus 로고
    • Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes
    • Miyazaki Y, Matsuda M, DeFronzo RA. Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes. Diabetes Care 2002;25:517-23.
    • (2002) Diabetes Care , vol.25 , pp. 517-523
    • Miyazaki, Y.1    Matsuda, M.2    DeFronzo, R.A.3
  • 41
    • 0036776903 scopus 로고    scopus 로고
    • Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients
    • Carey DG, Cowin GJ, Galloway GJ, et al. Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients. Obes Res 2002;10:1008-15. [Erratum, Obes Res 2002;10:following table of contents.]
    • (2002) Obes Res , vol.10 , pp. 1008-1015
    • Carey, D.G.1    Cowin, G.J.2    Galloway, G.J.3
  • 42
    • 0036776903 scopus 로고    scopus 로고
    • Erratum
    • following table of contents
    • Carey DG, Cowin GJ, Galloway GJ, et al. Effect of rosiglitazone on insulin sensitivity and body composition in type 2 diabetic patients. Obes Res 2002;10:1008-15. [Erratum, Obes Res 2002;10:following table of contents.]
    • (2002) Obes Res , vol.10
  • 43
    • 17544396164 scopus 로고    scopus 로고
    • Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation
    • Adams M, Montague CT, Prins JB, et al. Activators of peroxisome proliferator-activated receptor gamma have depot-specific effects on human preadipocyte differentiation. J Clin Invest 1997;100:3149-53.
    • (1997) J Clin Invest , vol.100 , pp. 3149-3153
    • Adams, M.1    Montague, C.T.2    Prins, J.B.3
  • 44
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
    • Okuno A, Tamemoto H, Tobe K, et al. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest 1998;101:1354-61.
    • (1998) J Clin Invest , vol.101 , pp. 1354-1361
    • Okuno, A.1    Tamemoto, H.2    Tobe, K.3
  • 45
    • 0036310037 scopus 로고    scopus 로고
    • The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes
    • Mayerson AB, Hundal RS, Dufour S, et al. The effects of rosiglitazone on insulin sensitivity, lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes 2002;51:797-802.
    • (2002) Diabetes , vol.51 , pp. 797-802
    • Mayerson, A.B.1    Hundal, R.S.2    Dufour, S.3
  • 46
    • 0037567697 scopus 로고    scopus 로고
    • Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes
    • Bajaj M, Suraamornkul S, Pratipanawatr T, et al. Pioglitazone reduces hepatic fat content and augments splanchnic glucose uptake in patients with type 2 diabetes. Diabetes 2003;52:1364-70.
    • (2003) Diabetes , vol.52 , pp. 1364-1370
    • Bajaj, M.1    Suraamornkul, S.2    Pratipanawatr, T.3
  • 47
    • 3242745192 scopus 로고    scopus 로고
    • Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance and gene expression in adipose tissue in patients with type 2 diabetes
    • Tiikkainen M, Häkkinen A-M, Korsheninnikova E, Nyman T, Mäkimattila S, Yki-Järvinen H. Effects of rosiglitazone and metformin on liver fat content, hepatic insulin resistance, insulin clearance and gene expression in adipose tissue in patients with type 2 diabetes. Diabetes 2004;53:2169-76.
    • (2004) Diabetes , vol.53 , pp. 2169-2176
    • Tiikkainen, M.1    Häkkinen, A.-M.2    Korsheninnikova, E.3    Nyman, T.4    Mäkimattila, S.5    Yki-Järvinen, H.6
  • 48
    • 0043157304 scopus 로고    scopus 로고
    • Rosiglitazone in the treatment of HAART-associated lipodystrophy - A randomized double-blind placebo-controlled study
    • Sutinen J, Häkinen A-M, Westerbacka J, et al. Rosiglitazone in the treatment of HAART-associated lipodystrophy - a randomized double-blind placebo-controlled study. Antivir Ther 2003;8:199-207.
    • (2003) Antivir Ther , vol.8 , pp. 199-207
    • Sutinen, J.1    Häkinen, A.-M.2    Westerbacka, J.3
  • 49
    • 9144229185 scopus 로고    scopus 로고
    • Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle
    • He W, Barak Y, Hevener A, et al. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A 2003;100: 15712-7.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 15712-15717
    • He, W.1    Barak, Y.2    Hevener, A.3
  • 50
    • 0346027235 scopus 로고    scopus 로고
    • Muscle-specific Pparg deletion causes insulin resistance
    • Hevener AL, He W, Barak Y, et al. Muscle-specific Pparg deletion causes insulin resistance. Nat Med 2003;9:1491-7.
    • (2003) Nat Med , vol.9 , pp. 1491-1497
    • Hevener, A.L.1    He, W.2    Barak, Y.3
  • 51
    • 0141446024 scopus 로고    scopus 로고
    • Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
    • Gavrilova O, Haluzik M, Matsusue K, et al. Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem 2003;278: 34268-76.
    • (2003) J Biol Chem , vol.278 , pp. 34268-34276
    • Gavrilova, O.1    Haluzik, M.2    Matsusue, K.3
  • 53
    • 0033547443 scopus 로고    scopus 로고
    • Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes
    • Rieusset J, Auwerx J, Vidal H. Regulation of gene expression by activation of the peroxisome proliferator-activated receptor gamma with rosiglitazone (BRL 49653) in human adipocytes. Biochem Biophys Res Commun 1999;265:265-71.
    • (1999) Biochem Biophys Res Commun , vol.265 , pp. 265-271
    • Rieusset, J.1    Auwerx, J.2    Vidal, H.3
  • 54
    • 0035172839 scopus 로고    scopus 로고
    • Thiazolidinediones (PPARgamma agonists) but not PPARalpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes
    • Smith U, Gogg S, Johansson A, Olausson T, Rotter V, Svalstedt B. Thiazolidinediones (PPARgamma agonists) but not PPARalpha agonists increase IRS-2 gene expression in 3T3-L1 and human adipocytes. FASEB J 2001;15:215-20.
    • (2001) FASEB J , vol.15 , pp. 215-220
    • Smith, U.1    Gogg, S.2    Johansson, A.3    Olausson, T.4    Rotter, V.5    Svalstedt, B.6
  • 55
    • 0036063777 scopus 로고    scopus 로고
    • Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
    • Maeda N, Shimomura I, Kishida K, et al. Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med 2002;8:731-7.
    • (2002) Nat Med , vol.8 , pp. 731-737
    • Maeda, N.1    Shimomura, I.2    Kishida, K.3
  • 56
    • 0037020170 scopus 로고    scopus 로고
    • Role of adiponectin in preventing vascular stenosis: The missing link of adipo-vascular axis
    • Matsuda M, Shimomura I, Sata M, et al. Role of adiponectin in preventing vascular stenosis: the missing link of adipo-vascular axis. J Biol Chem 2002;277:37487-91.
    • (2002) J Biol Chem , vol.277 , pp. 37487-37491
    • Matsuda, M.1    Shimomura, I.2    Sata, M.3
  • 57
    • 0031892271 scopus 로고    scopus 로고
    • TNF-alpha and insulin resistance: Summary and future prospects
    • Peraldi P, Spiegelman B. TNF-alpha and insulin resistance: summary and future prospects. Mol Cell Biochem 1998;182:169-75.
    • (1998) Mol Cell Biochem , vol.182 , pp. 169-175
    • Peraldi, P.1    Spiegelman, B.2
  • 58
    • 0035905758 scopus 로고    scopus 로고
    • The hormone resistin links obesity to diabetes
    • Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes. Nature 2001;409:307-12.
    • (2001) Nature , vol.409 , pp. 307-312
    • Steppan, C.M.1    Bailey, S.T.2    Bhat, S.3
  • 59
    • 0035918143 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta-hydroxysteroid dehydrogenase type 1 expression and activity
    • Berger J, Tanen M, Elbrecht A, et al. Peroxisome proliferator-activated receptor-gamma ligands inhibit adipocyte 11beta-hydroxysteroid dehydrogenase type 1 expression and activity. J Biol Chem 2001;276: 12629-35.
    • (2001) J Biol Chem , vol.276 , pp. 12629-12635
    • Berger, J.1    Tanen, M.2    Elbrecht, A.3
  • 60
    • 0035824440 scopus 로고    scopus 로고
    • A transgenic model of visceral obesity and the metabolic syndrome
    • Masuzaki H, Paterson J, Shinyama H, et al. A transgenic model of visceral obesity and the metabolic syndrome. Science 2001; 294:2166-70.
    • (2001) Science , vol.294 , pp. 2166-2170
    • Masuzaki, H.1    Paterson, J.2    Shinyama, H.3
  • 61
    • 0035462629 scopus 로고    scopus 로고
    • PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein
    • Maeda N, Takahashi M, Funahashi T, et al. PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes 2001; 50:2094-9.
    • (2001) Diabetes , vol.50 , pp. 2094-2099
    • Maeda, N.1    Takahashi, M.2    Funahashi, T.3
  • 62
    • 0034096988 scopus 로고    scopus 로고
    • Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients
    • Hotta K, Funahashi T, Arita Y, et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol 2000;20:1595-9.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 1595-1599
    • Hotta, K.1    Funahashi, T.2    Arita, Y.3
  • 63
    • 0033515761 scopus 로고    scopus 로고
    • Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
    • Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 1999;257:79-83.
    • (1999) Biochem Biophys Res Commun , vol.257 , pp. 79-83
    • Arita, Y.1    Kihara, S.2    Ouchi, N.3
  • 64
    • 0036125944 scopus 로고    scopus 로고
    • Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes
    • Hirose H, Kawai T, Yamamoto Y, et al. Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes. Metabolism 2002;51: 314-7.
    • (2002) Metabolism , vol.51 , pp. 314-317
    • Hirose, H.1    Kawai, T.2    Yamamoto, Y.3
  • 65
    • 0037342120 scopus 로고    scopus 로고
    • Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy
    • Phillips SA, Ciaraldi TP, Kong AP, et al. Modulation of circulating and adipose tissue adiponectin levels by antidiabetic therapy. Diabetes 2003;52:667-74.
    • (2003) Diabetes , vol.52 , pp. 667-674
    • Phillips, S.A.1    Ciaraldi, T.P.2    Kong, A.P.3
  • 66
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Yu JG, Javorschi S, Hevener AL, et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 2002;51: 2968-74.
    • (2002) Diabetes , vol.51 , pp. 2968-2974
    • Yu, J.G.1    Javorschi, S.2    Hevener, A.L.3
  • 67
    • 0034999667 scopus 로고    scopus 로고
    • Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
    • Weyer C, Funahashi T, Tanaka S, et al. Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 2001;86:1930-5.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1930-1935
    • Weyer, C.1    Funahashi, T.2    Tanaka, S.3
  • 70
    • 0037323424 scopus 로고    scopus 로고
    • Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy
    • Addy CL, Gavrila A, Tsiodras S, Brodovicz K, Karchmer AW, Mantzoros CS. Hypoadiponectinemia is associated with insulin resistance, hypertriglyceridemia, and fat redistribution in human immunodeficiency virus-infected patients treated with highly active antiretroviral therapy. J Clin Endocrinol Metab 2003;88:627-36.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 627-636
    • Addy, C.L.1    Gavrila, A.2    Tsiodras, S.3    Brodovicz, K.4    Karchmer, A.W.5    Mantzoros, C.S.6
  • 71
    • 0038697822 scopus 로고    scopus 로고
    • Circulating concentration of adiponectin and its expression in subcutaneous adipose tissue in patients with highly active antiretroviral therapy-associated lipodystrophy
    • Sutinen J, Korsheninnikova E, Funahashi T, Matsuzawa Y, Nyman T, Yki-Järvinen H. Circulating concentration of adiponectin and its expression in subcutaneous adipose tissue in patients with highly active antiretroviral therapy-associated lipodystrophy. J Clin Endocrinol Metab 2003;88:1907-10.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 1907-1910
    • Sutinen, J.1    Korsheninnikova, E.2    Funahashi, T.3    Matsuzawa, Y.4    Nyman, T.5    Yki-Järvinen, H.6
  • 72
    • 0036481709 scopus 로고    scopus 로고
    • Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
    • Yang WS, Jeng CY, Wu TJ, et al. Synthetic peroxisome proliferator- activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care 2002;25:376-80.
    • (2002) Diabetes Care , vol.25 , pp. 376-380
    • Yang, W.S.1    Jeng, C.Y.2    Wu, T.J.3
  • 73
    • 4243645912 scopus 로고    scopus 로고
    • Induction of adipocyte complement-related protein of 30 kilodaltons by PPAKgamma agonists: A potential mechanism of insulin sensitization
    • Combs TP, Wagner JA, Berger J, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPAKgamma agonists: a potential mechanism of insulin sensitization. Endocrinology 2002;143:998-1007.
    • (2002) Endocrinology , vol.143 , pp. 998-1007
    • Combs, T.P.1    Wagner, J.A.2    Berger, J.3
  • 74
    • 0029980285 scopus 로고    scopus 로고
    • cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1)
    • Maeda K, Okubo K, Shimomura I, Funahashi T, Matsuzawa Y, Matsubara K. cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1). Biochem Biophys Res Commun 1996;221: 286-9.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 286-289
    • Maeda, K.1    Okubo, K.2    Shimomura, I.3    Funahashi, T.4    Matsuzawa, Y.5    Matsubara, K.6
  • 75
    • 0034170720 scopus 로고    scopus 로고
    • How will we know if 11beta-hydroxysteroid dehydrogenases are important in common diseases
    • Walker BR. How will we know if 11beta-hydroxysteroid dehydrogenases are important in common diseases. Clin Endocrinol (Oxf) 2000;52:401-2.
    • (2000) Clin Endocrinol (Oxf) , vol.52 , pp. 401-402
    • Walker, B.R.1
  • 76
    • 0242696221 scopus 로고    scopus 로고
    • Lipid overload and overflow: Metabolic trauma and the metabolic syndrome
    • Unger RH. Lipid overload and overflow: metabolic trauma and the metabolic syndrome. Trends Endocrinol Metab 2003;14: 398-403.
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 398-403
    • Unger, R.H.1
  • 77
    • 0035832506 scopus 로고    scopus 로고
    • Lessons from the glitazones: A story of drug development
    • Gale EA. Lessons from the glitazones: a story of drug development. Lancet 2001; 357:1870-5.
    • (2001) Lancet , vol.357 , pp. 1870-1875
    • Gale, E.A.1
  • 78
    • 0037167920 scopus 로고    scopus 로고
    • Initial management of glycemia in type 2 diabetes mellitus
    • Nathan DM. Initial management of glycemia in type 2 diabetes mellitus. N Engl J Med 2002;347:1342-9.
    • (2002) N Engl J Med , vol.347 , pp. 1342-1349
    • Nathan, D.M.1
  • 79
    • 0029099086 scopus 로고
    • Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus
    • DeFronzo RA, Goodman AM, Multicenter Metformin Study Group. Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. N Engl J Med 1995;333:541-9.
    • (1995) N Engl J Med , vol.333 , pp. 541-549
    • DeFronzo, R.A.1    Goodman, A.M.2
  • 80
    • 0036781182 scopus 로고    scopus 로고
    • A Diabetes Outcome Progression Trial (ADOPT): An international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes
    • Viberti G, Kahn SE, Greene DA, et al. A Diabetes Outcome Progression Trial (ADOPT): an international multicenter study of the comparative efficacy of rosiglitazone, glyburide, and metformin in recently diagnosed type 2 diabetes. Diabetes Care 2002;25:1737-43.
    • (2002) Diabetes Care , vol.25 , pp. 1737-1743
    • Viberti, G.1    Kahn, S.E.2    Greene, D.A.3
  • 81
    • 0036551421 scopus 로고    scopus 로고
    • A prospective, randomized comparison of the metabolic effects of pioglitazone or rosiglitazone in patients with type 2 diabetes who were previously treated with troglitazone
    • Khan MA, St Peter JV, Xue JL. A prospective, randomized comparison of the metabolic effects of pioglitazone or rosiglitazone in patients with type 2 diabetes who were previously treated with troglitazone. Diabetes Care 2002;25:708-11.
    • (2002) Diabetes Care , vol.25 , pp. 708-711
    • Khan, M.A.1    St. Peter, J.V.2    Xue, J.L.3
  • 82
    • 0034735992 scopus 로고    scopus 로고
    • Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone
    • Sakamoto J, Kimura H, Moriyama S, et al. Activation of human peroxisome proliferator-activated receptor (PPAR) subtypes by pioglitazone. Biochem Biophys Res Commun 2000;278:704-11.
    • (2000) Biochem Biophys Res Commun , vol.278 , pp. 704-711
    • Sakamoto, J.1    Kimura, H.2    Moriyama, S.3
  • 83
    • 0030986959 scopus 로고    scopus 로고
    • Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM
    • Malmström R, Packard CJ, Caslake M, et al. Defective regulation of triglyceride metabolism by insulin in the liver in NIDDM. Diabetologia 1997;40:454-62.
    • (1997) Diabetologia , vol.40 , pp. 454-462
    • Malmström, R.1    Packard, C.J.2    Caslake, M.3
  • 87
    • 0038805259 scopus 로고    scopus 로고
    • The prevalence and etiology of elevated amino-transferase levels in the United States
    • Clark JM, Brancati FL, Diehl AM. The prevalence and etiology of elevated amino-transferase levels in the United States. Am J Gastroenterol 2003;98:960-7.
    • (2003) Am J Gastroenterol , vol.98 , pp. 960-967
    • Clark, J.M.1    Brancati, F.L.2    Diehl, A.M.3
  • 88
    • 0036263238 scopus 로고    scopus 로고
    • High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Stefan N, Lindsay RS, et al. High alanine aminotransferase is associated with decreased hepatic insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 2002;51:1889-95.
    • (2002) Diabetes , vol.51 , pp. 1889-1895
    • Vozarova, B.1    Stefan, N.2    Lindsay, R.S.3
  • 89
    • 0036312905 scopus 로고    scopus 로고
    • Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men
    • Seppälä-Lindroos A, Vehkavaara S, Häkinen AM, et al. Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men. J Clin Endocrinol Metab 2002;87:3023-8.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3023-3028
    • Seppälä-Lindroos, A.1    Vehkavaara, S.2    Häkinen, A.M.3
  • 90
    • 0342314436 scopus 로고    scopus 로고
    • Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients
    • Ryysy L, Häkkinen AM, Goto T, et al. Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients. Diabetes 2000;49:749-58.
    • (2000) Diabetes , vol.49 , pp. 749-758
    • Ryysy, L.1    Häkkinen, A.M.2    Goto, T.3
  • 91
    • 0141532275 scopus 로고    scopus 로고
    • Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone
    • Neuschwander-Tetri BA, Brunt EM, Wehmeier KR, Oliver D, Bacon BR. Improved nonalcoholic steatohepatitis after 48 weeks of treatment with the PPAR-gamma ligand rosiglitazone. Hepatology 2003;38: 1008-17.
    • (2003) Hepatology , vol.38 , pp. 1008-1017
    • Neuschwander-Tetri, B.A.1    Brunt, E.M.2    Wehmeier, K.R.3    Oliver, D.4    Bacon, B.R.5
  • 92
    • 1442355447 scopus 로고    scopus 로고
    • A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis
    • Promrat K, Lutchman G, Uwaifo GI, et al. A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis. Hepatology 2004;39:188-96.
    • (2004) Hepatology , vol.39 , pp. 188-196
    • Promrat, K.1    Lutchman, G.2    Uwaifo, G.I.3
  • 93
    • 0031773509 scopus 로고    scopus 로고
    • Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: A prospective study
    • Knochenhauer ES, Key TJ, Kahsar-Miller M, Waggoner W, Boots LR, Azziz P. Prevalence of the polycystic ovary syndrome in unselected black and white women of the southeastern United States: a prospective study. J Clin Endocrinol Metab 1998;83: 3078-82.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 3078-3082
    • Knochenhauer, E.S.1    Key, T.J.2    Kahsar-Miller, M.3    Waggoner, W.4    Boots, L.R.5    Azziz, P.6
  • 94
    • 0033014327 scopus 로고    scopus 로고
    • The epidemiology of polycystic ovary syndrome: Prevalence and associated disease risks
    • Solomon CG. The epidemiology of polycystic ovary syndrome: prevalence and associated disease risks. Endocrinol Metab Clin North Am 1999;28:247-63.
    • (1999) Endocrinol Metab Clin North Am , vol.28 , pp. 247-263
    • Solomon, C.G.1
  • 95
    • 0026028184 scopus 로고
    • A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome
    • Nestler JE, Powers LP, Matt DW, et al. A direct effect of hyperinsulinemia on serum sex hormone-binding globulin levels in obese women with the polycystic ovary syndrome. J Clin Endocrinol Metab 1991;72: 83-9.
    • (1991) J Clin Endocrinol Metab , vol.72 , pp. 83-89
    • Nestler, J.E.1    Powers, L.P.2    Matt, D.W.3
  • 96
    • 0035079896 scopus 로고    scopus 로고
    • Insulin-lowering drugs in polycystic ovary syndrome
    • Iuomo MJ, Nestler JE. Insulin-lowering drugs in polycystic ovary syndrome. Obstet Gynecol Clin North Am 2001;28:153-64.
    • (2001) Obstet Gynecol Clin North Am , vol.28 , pp. 153-164
    • Iuomo, M.J.1    Nestler, J.E.2
  • 97
    • 0035041906 scopus 로고    scopus 로고
    • Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: A multicenter, double blind, placebo-controlled trial
    • Azziz R, Ehrmann D, Legro RS, et al. Troglitazone improves ovulation and hirsutism in the polycystic ovary syndrome: a multicenter, double blind, placebo-controlled trial. J Clin Endocrinol Metab 2001;86: 1626-32.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 1626-1632
    • Azziz, R.1    Ehrmann, D.2    Legro, R.S.3
  • 98
    • 0037336327 scopus 로고    scopus 로고
    • Effect of rosiglitazone on spontaneous and clomiphene citrate-induced ovulation in women with polycystic ovary syndrome
    • Ghazeeri G, Kutteh WH, Bryer-Ash M, Haas D, Ke RW. Effect of rosiglitazone on spontaneous and clomiphene citrate-induced ovulation in women with polycystic ovary syndrome. Fertil Steril 2003;79:562-6.
    • (2003) Fertil Steril , vol.79 , pp. 562-566
    • Ghazeeri, G.1    Kutteh, W.H.2    Bryer-Ash, M.3    Haas, D.4    Ke, R.W.5
  • 99
    • 0034699898 scopus 로고    scopus 로고
    • Adverse effects of antiretroviral therapy
    • Carr A, Cooper DA. Adverse effects of antiretroviral therapy. Lancet 2000;356: 1423-30.
    • (2000) Lancet , vol.356 , pp. 1423-1430
    • Carr, A.1    Cooper, D.A.2
  • 100
    • 0034663140 scopus 로고    scopus 로고
    • Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes
    • Arioglu E, Duncan-Morin J, Sebring N, et al. Efficacy and safety of troglitazone in the treatment of lipodystrophy syndromes. Ann Intern Med 2000;133:263-74.
    • (2000) Ann Intern Med , vol.133 , pp. 263-274
    • Arioglu, E.1    Duncan-Morin, J.2    Sebring, N.3
  • 101
    • 0032560807 scopus 로고    scopus 로고
    • Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction
    • Haffner SM, Lehto S, Rönnemaa T, Pyörälä K, Laakso M. Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. N Engl J Med 1998;339:229-34.
    • (1998) N Engl J Med , vol.339 , pp. 229-234
    • Haffner, S.M.1    Lehto, S.2    Rönnemaa, T.3    Pyörälä, K.4    Laakso, M.5
  • 102
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-52. [Erratum, Lancet 1999;354:602.]
    • (1998) Lancet , vol.352 , pp. 837-852
  • 103
    • 0032511583 scopus 로고    scopus 로고
    • Erratum
    • UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet 1998;352:837-52. [Erratum, Lancet 1999;354:602.]
    • (1999) Lancet , vol.354 , pp. 602
  • 104
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • Idem. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998;352:854-65. [Erratum, Lancet 1998;352:1557.]
    • (1998) Lancet , vol.352 , pp. 854-865
  • 105
    • 0032511566 scopus 로고    scopus 로고
    • Erratum
    • Idem. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 1998;352:854-65. [Erratum, Lancet 1998;352:1557.]
    • (1998) Lancet , vol.352 , pp. 1557
  • 106
    • 0034819464 scopus 로고    scopus 로고
    • Combination therapies with insulin in type 2 diabetes
    • Yki-Järvinen H. Combination therapies with insulin in type 2 diabetes. Diabetes Care 2001;24:758-67.
    • (2001) Diabetes Care , vol.24 , pp. 758-767
    • Yki-Järvinen, H.1
  • 107
    • 1842855369 scopus 로고    scopus 로고
    • Clinical effectiveness and cost-effectiveness of pioglitazone and rosiglitazone in the treatment of type 2 diabetes: A systematic review and economic evaluation
    • Czoski-Murray C, Warren E, Chilcott J, Beverley C, Psyllaki MA, Cowan J. Clinical effectiveness and cost-effectiveness of pioglitazone and rosiglitazone in the treatment of type 2 diabetes: a systematic review and economic evaluation. Health Technol Assess 2004;8(13):1-91.
    • (2004) Health Technol Assess , vol.8 , Issue.13 , pp. 1-91
    • Czoski-Murray, C.1    Warren, E.2    Chilcott, J.3    Beverley, C.4    Psyllaki, M.A.5    Cowan, J.6
  • 108
    • 0037231459 scopus 로고    scopus 로고
    • Association of hypoadiponectinemia with coronary artery disease in men
    • Kumada M, Kihara S, Sumitsuji S, et al. Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol 2003;23:85-9.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 85-89
    • Kumada, M.1    Kihara, S.2    Sumitsuji, S.3
  • 109
    • 0037390373 scopus 로고    scopus 로고
    • Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy
    • Yki-Järvinen H, Sutinen J, Silveira A, et al. Regulation of plasma PAI-1 concentrations in HAART-associated lipodystrophy during rosiglitazone therapy. Arterioscler Thromb Vasc Biol 2003;23:688-94.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 688-694
    • Yki-Järvinen, H.1    Sutinen, J.2    Silveira, A.3
  • 110
    • 0037031267 scopus 로고    scopus 로고
    • Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus
    • Haffner SM, Greenberg AS, Weston WM, Chen H, Williams K, Freed MI. Effect of rosiglitazone treatment on nontraditional markers of cardiovascular disease in patients with type 2 diabetes mellitus. Circulation 2002;106:679-84.
    • (2002) Circulation , vol.106 , pp. 679-684
    • Haffner, S.M.1    Greenberg, A.S.2    Weston, W.M.3    Chen, H.4    Williams, K.5    Freed, M.I.6
  • 111
    • 0037324289 scopus 로고    scopus 로고
    • Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease
    • Marx N, Froehlich J, Siam L, et al. Antidiabetic PPAR gamma-activator rosiglitazone reduces MMP-9 serum levels in type 2 diabetic patients with coronary artery disease. Arterioscler Thromb Vasc Biol 2003; 23:283-8.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 283-288
    • Marx, N.1    Froehlich, J.2    Siam, L.3
  • 112
    • 0037302089 scopus 로고    scopus 로고
    • The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: A placebo-controlled randomized clinical trial
    • Caballero AE, Saouaf K, Lim SC, et al. The effects of troglitazone, an insulin-sensitizing agent, on the endothelial function in early and late type 2 diabetes: a placebo-controlled randomized clinical trial. Metabolism 2003;52:173-80.
    • (2003) Metabolism , vol.52 , pp. 173-180
    • Caballero, A.E.1    Saouaf, K.2    Lim, S.C.3
  • 113
    • 2442626743 scopus 로고    scopus 로고
    • Effect of rosiglitazone on common carotid intima-media thickness progression in coronary artery disease patients without diabetes mellitus
    • Sidhu JS, Kaposzta Z, Markus HS, Kaski JC. Effect of rosiglitazone on common carotid intima-media thickness progression in coronary artery disease patients without diabetes mellitus. Arterioscler Thromb Vasc Biol 2004;24:930-4.
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , pp. 930-934
    • Sidhu, J.S.1    Kaposzta, Z.2    Markus, H.S.3    Kaski, J.C.4
  • 114
    • 0012459772 scopus 로고    scopus 로고
    • The PROactive study: Preliminary baseline characteristics in 1843 patients
    • abstract
    • Charbonnel B, Dormandy JA, Erdmann E, Massi-Benedetti M. The PROactive study: preliminary baseline characteristics in 1843 patients. Diabetologia 2002;45: A107. abstract.
    • (2002) Diabetologia , vol.45
    • Charbonnel, B.1    Dormandy, J.A.2    Erdmann, E.3    Massi-Benedetti, M.4
  • 115
    • 0036581153 scopus 로고    scopus 로고
    • Evaluation of liver function in type 2 diabetic patients during clinical trials: Evidence that rosiglitazone does not cause hepatic dysfunction
    • Lebovitz HE, Kreider M, Freed MI. Evaluation of liver function in type 2 diabetic patients during clinical trials: evidence that rosiglitazone does not cause hepatic dysfunction. Diabetes Care 2002;25:815-21.
    • (2002) Diabetes Care , vol.25 , pp. 815-821
    • Lebovitz, H.E.1    Kreider, M.2    Freed, M.I.3
  • 116
    • 0036847135 scopus 로고    scopus 로고
    • AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats
    • Ljung B, Bamberg K, Dahllof B, et al. AZ 242, a novel PPARalpha/gamma agonist with beneficial effects on insulin resistance and carbohydrate and lipid metabolism in ob/ob mice and obese Zucker rats. J Lipid Res 2002;43:1855-63.
    • (2002) J Lipid Res , vol.43 , pp. 1855-1863
    • Ljung, B.1    Bamberg, K.2    Dahllof, B.3
  • 117
    • 0030071445 scopus 로고    scopus 로고
    • Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones
    • Katzenellenbogen JA, O'Malley BW, Katzenellenbogen BS. Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol Endocrinol 1996;10: 119-31.
    • (1996) Mol Endocrinol , vol.10 , pp. 119-131
    • Katzenellenbogen, J.A.1    O'Malley, B.W.2    Katzenellenbogen, B.S.3
  • 118
    • 0037434618 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators - Mechanisms of action and application to clinical practice
    • Riggs BL, Hartmann LC. Selective estrogen-receptor modulators - mechanisms of action and application to clinical practice. N Engl J Med 2003;348:618-29. [Erratum, N Engl J Med 2003;348:1192.]
    • (2003) N Engl J Med , vol.348 , pp. 618-629
    • Riggs, B.L.1    Hartmann, L.C.2
  • 119
    • 0037456732 scopus 로고    scopus 로고
    • Erratum
    • Riggs BL, Hartmann LC. Selective estrogen-receptor modulators - mechanisms of action and application to clinical practice. N Engl J Med 2003;348:618-29. [Erratum, N Engl J Med 2003;348:1192.]
    • (2003) N Engl J Med , vol.348 , pp. 1192
  • 120
    • 7844224790 scopus 로고    scopus 로고
    • N-(2-benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents
    • Henke BR, Blanchard SG, Brackeen MF, et al. N-(2-benzoylphenyl)-L- tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents. J Med Chem 1998;41:5020-36.
    • (1998) J Med Chem , vol.41 , pp. 5020-5036
    • Henke, B.R.1    Blanchard, S.G.2    Brackeen, M.F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.