Activation of toll-like receptor 2 on microglia promotes cell uptake of alzheimer disease-associated amyloid β peptide

Journal of Biological Chemistry

Volumn 281, Issue 6, 2006, Pages 3651-3659

  Chen, Keqiang ^a,c   Iribarren, Pablo ^a   Hu, Jinyue ^a   Chen, Jianhong ^a   Gong, Wanghua ^b   Cho, Edward H ^b   Lockett, Stephen ^b   Dunlop, Nancy M ^a   Ji, Ming Wang ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BRAIN; CELLS; DISEASES; LIPIDS; POLYSACCHARIDES; RNA;

FORMYL PEPTIDE RECEPTOR-LIKE 1 (FPRL1); MOUSE MICROGLIAL CELLS; NEURODEGENERATIVE DISEASES; PEPTIDOGLYCAN (PGN);

POLYPEPTIDES;

AMYLOID BETA PROTEIN[1-42]; FORMYLPEPTIDE RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDOGLYCAN; TOLL LIKE RECEPTOR 2; AMYLOID BETA PROTEIN; CALCIUM; FPRL1 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIGAND; LIPOPOLYSACCHARIDE; LIPOXIN RECEPTOR; MESSENGER RNA; PEPTIDE; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ARTICLE; CHEMOTAXIS; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; STAPHYLOCOCCUS AUREUS; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; CONFOCAL MICROSCOPY; DEGENERATIVE DISEASE; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; INFLAMMATION; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

BACTERIA (MICROORGANISMS); POSIBACTERIA; STAPHYLOCOCCUS AUREUS;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BLOTTING, WESTERN; CALCIUM; CHEMOTAXIS; FLOW CYTOMETRY; INFLAMMATION; LIGANDS; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; MICE; MICROGLIA; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MODELS, BIOLOGICAL; NEURODEGENERATIVE DISEASES; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PEPTIDES; PEPTIDOGLYCAN; RECEPTORS, FORMYL PEPTIDE; RECEPTORS, LIPOXIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2; TRANSFECTION;

EID: 33645650780     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508125200     Document Type: Article

References (54)

1. Morgan, C., Colombres, M., and Nunez, M. T. (2004) Prog. Neurobiol. 74, 323-349
2. Eikelenboom, P., Rozemuller, J. M., and Muiswinkel, F. L. (1998) Exp. Neurol. 154, 89-98
3. Cotter, R. L., Burke, W. J., Thomas, V. S., Potter, J. F., Zheng, J., and Gendelman, H. E. (1999) J. Leukocyte Biol. 65, 416-427
4. McGeer, P. L., and McGeer, E. G. (1999) J. Leukocyte Biol. 65, 409-415
5. Iribarren, P., Zhou, Y., Hu, J., Le, Y., and Wang, J. M. (2005) Immunol. Res. 31, 165-176
6. Wegiel, J., Wang, K. C., Tarnawski, M., and Lach, B. (2000) Acta Neuropathol. 100, 356-364
7. Wisniewski, H. M., and Wegiel, J. (1994) Appl. Neurobiol. 20, 192-194
8. Rogers, J., and Lue, L. F. (2001) Neurochem. Int. 39, 333-340
9. Rogers, J., Strohmeyer, R., Kovelowski, C. J., and Li, R. (2002) Glia 40, 260-269
10. Tiffany, H. L., Lavigne, M. C., Cui, Y. H., Wang, J. M., Leto, T. L., Gao, J. L., and Murphy, P. M. (2001) J. Biol. Chem. 276, 23645-23652
11. Le, Y., Gong, W., Tiffany, H. L., Tumanov, A., Nedospasov, S., Shen, W., Dunlop, N. M., Gao, J. L., Murphy, P. M., Oppenheim, J. J., and Wang, J. M. (2001) J. Neurosci. 21, RC123
12. Giulian, D. (1999) Am. J. Hum. Genet. 65, 13-18
13. Cui, Y., Le, Y., Yazawa, H., Gong, W., and Wang, J. M. (2002) J. Leukocyte Biol. 72, 628-635
14. Yazawa, H., Yu, Z. X., Takeda, K., Le, Y., Gong, W., Ferrans, V. J., Oppenheim, J. J., Li, C. C., and Wang, J. M. (2001) FASEB J. 15, 2454-2462
15. Ying, G., Iribarren, P., Zhou, Y., Gong, W., Zhang, N., Yu, Z. X., Le, Y., Cui, Y., and Wang, J. M. (2004) J. Immunol. 172, 7078-7085
16. Cui, Y. H., Le, Y., Gong, W., Proost, P., Van Damme, J., Murphy, W. J., and Wang, J. M. (2002) J. Immunol. 168, 434-442
17. Cui, Y. H., Le, Y., Zhang, X., Gong W., Abe, K., Sun, R., Van Damme, J., Proost, P., and Wang, J. M. (2002) Neurobiol. Dis. 10, 366-377
18. Kielian, T., Esen, N., and Bearden, E. D. (2005) Glia 49, 567-576
19. Kielian, T., Mayes, P., and Kielian, M. (2002) J. Neuroimmunol. 130, 86-99
20. Le, Y., Murphy, P. M., and Wang, J. M. (2002) Trends Immunol. 23, 541-548
21. Carl, V. S., Steinke, K. B., Nicklin, M., and Smith, M. F. (2002) J. Biol. Chem. 77, 17448-17456
22. Karin, M. (1999) Oncogene 18, 6867-6874
23. Rock, R. B., Genya, G., Shuxian, H., Wen, S. S., Maxim, C., Lokensgard, J. R., and Peterson, P. K. (2004) Clin. Microbiol. Rev. 17, 942-964
24. Monsonego, A., and Weiner, H. L. (2003) Science 302, 834-838
25. Hirsch, E. C., Breidert, T., Rousselet, E., Hunot, S., Hartmann, A., and Michel, P. P. (2003) Ann. N. Y. Acad. Sci. 991, 214-228
26. Minagar, A., Shapshak, P., Fujimura, R., Ownby, R., Heyes, M., and Eisdorfer, C. (2002) J. Neurol. Sci. 202, 13-23
27. Pocock, J. M., Liddle, A. C., Hooper, C., Taylor, D. L., Davenport, C. M., and Morgan, S. C. (2002) Ernst Schering Res. Found. Workshop 39, 105-132
28. Iribarren, P., Cui, Y. H., Le, Y., Ying, G., Zhang, X., Gong, W., and Wang, J. M. (2003) J. Immunol. 171, 5482-5488
29. Kalaria, R. N. (1999) Curr. Opin. Hematol. 6, 15-24
30. Akiyama, H., Barger, S., Barnum, S., Bradt, B., Bauer, J., Cole, G. M., Cooper, N. R., Eikelenboom, P., Emmerling, M., Fiebich, B. L., Finch, C. E., Frautschy, S., Griffin, W. S., Hampel, H., Hull, M., Landreth, G., Lue, L., Mrak, R., Mackenzie, I. R., McGeer, P. L., O'Banion, M. K., Pachter, J., Pasinetti, G., Plata-Salaman, C., Rogers, J., Rydel, R., Shen, Y., Streit, W., Strohmeyer, R., Tooyoma, I., Van Muiswinkel, F. L., Veerhuis, R., Walker, D., Webster, S., Wegrzyniak, B., Wenk, G., and Wyss-Coray, T. (2000) Neurobiol. Aging 21, 383-421
31. Bsibsi, M., Ravid, R., Gveric, D., and van Noort, J. M. (2002) J. Neuropathol. Exp. Neurol. 61, 1013-1021
32. Olson, J. K., and Miller, S. D. (2004) J. Immunol. 173, 3916-3924
33. Laflamme, N., Echchannaoui, H., Landmann, R., and Rivest, S. (2003) Eur. J. Immunol. 33, 1127-1138
34. Zekki, H., Feinstein, D. L., and Rivest, S. (2002) Brain Pathol. 12, 308-319
35. Kielian, T. (2004) J. Neuroinflammation 17, 16
36. Kielian, T., Haney, A., Mayes, P. M., Garg, S., and Esen, N. (2005) Infect. Immun. 73, 7428-7435
37. Tsan, M. F., and Gao, B. (2004) J. Leukocyte Biol. 76, 514-519
38. Vabulas, R. M., Nejad, P. A., Ghose, S., Kirschning, C. J., Issels, R. D., and Wagner, H. (2002) J. Biol. Chem. 277, 15107-15112
39. Vabulas, R. M., Nejad, P. A., Costa, C., Kirschning, C. J., Hans, H., and Wagner, H. (2001) J. Biol. Chem. 276, 31332-31339
40. Vabulas, R. M., Braedel, S., Hilf, N., Singh-Jasuja, H., Herter, S., Ahmad-Nejad, P., Kirschning, C. J., Costa, C., Rammensee, H. G., Wagner, H., and Schild, H. (2002) J. Biol. Chem. 277, 20847-20853
41. Oppenheim, J. J., and Yang, D. (2005) Curr. Opin. Immunol. 17, 359-365
42. Grabiec, A., Meng, G., Fichte, S., Bessler, W., Wagner, H., and Kirschning, C. J. (2004) J. Biol. Chem. 279, 48004-48012
43. Frackowiak, J., Wisniewski, H. M., Wegiel, J., Merz, G. S., Iqbal, K., and Wang, K. C. (1992) Acta Neuropathol. 84, 225-233
44. Frautschy, S. A., Cole, G. M., and Baird, A. (1992) Am. J. Pathol. 140, 1389-1399
45. Shigematsu, K., McGeer, P. L., Walker, D. G., Ishii, T., and McGeer, E. G. (1992) J. Neurosci. Res. 31, 443-453
46. Frautschy, S. A., Yang, F., Irrizarry, M., Hyman, B., Saido, T. C., Hsiao, K., and Cole, G. M. (1998) Am. J. Pathol. 152, 307-317
47. Weldon, D. T., Rogers, S. D., Ghilardi, J. R., Finke, M. P., Cleary, J. P., O'Hare, E., Esler, W. P., Maggio, J. E., and Mantyh, P. W. (1998) J. Neurosci. 18, 2161-2173
48. Rogers, J., Lue, L. F., Walker, D. G., Yan, S. D., Stern, D., Strohmeyer, R., and Kovelowski, C. J. (2002) Ernst Schering Res. Found. Workshop 39, 25-44
49. Ard, M. D., Cole, G. M., Wei, J., Mehrle, A. P., and Fratkin, J. D. (1996) J. Neurosci. Res. 43, 190-202
50. Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., Kholodenko, D., Lee, M., Liao, Z., Lieberburg, I., Motter, R., Mutter, L., Soriano, F., Shopp, G., Vasquez, N., Vandevert, C., Walker, S., Wogulis, M., Yednock, T., Games, D., and Seubert, P. (1999) Nature 400, 173-177
51. Lombardo, J. A., Stern, E. A., McLellan, M. E., Kajdasz, S. T., Hickey, G. A., Bacskai, B. J., and Hyman, B. T. (2003) J. Neurosci. 23, 10879-10883
52. Wilcock, D. M., DiCarlo, G., Henderson, D., Jackson, J., Clarke, K., Ugen, K. E., Gordon, M. N., and Morgan, D. (2003) J. Neurosci. 23, 3745-3751
53. El-Khoury, J., Hickman, S. E., Thomas, C. A., Cao, L., Silverstein, S. C., and Loike, J. D. (1996) Nature 382, 716-719
54. Yan, S. D., Chen, X., Fu, J., Chen, M., Zhu, H., Roher, A., Slattery, T., Zhao, L., Nagashima, M., Morser, J., Migheli, A., Nawroth, P., Stern, D., and Schmidt, A. M. (1996) Nature 382, 685-691