Up-regulation of the inflammatory cytokines IFN-γ and IL-12 and down-regulation of IL-4 in cerebral cortex regions of APPSWE transgenic mice

Journal of Neuroimmunology

Volumn 126, Issue 1-2, 2002, Pages 50-57

  Abbas, Nagat ^a   Bednar, Ivan ^a   Mix, Eilhard ^b   Marie, Svedberg ^a   Paterson, David ^a   Ljungberg, Anna ^a   Morris, Chris ^c   Winblad, Bengt ^a   Nordberg, Agneta ^a   Zhu, Jie ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF ROSTOCK   (Germany)

^c NEWCASTLE GENERAL HOSPITAL   (United Kingdom)

Author keywords

amyloid; Alzheimer's disease; APP; APPSWE transgenic mouse; Cytokines

Indexed keywords

AMYLOID BETA PROTEIN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; MESSENGER RNA; PROTEIN PRECURSOR;

ALZHEIMER DISEASE; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; BRAIN REGION; CELL ACTIVATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; DOWN REGULATION; ENZYME KINETICS; FEMALE; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; INFLAMMATION; KINETICS; MALE; MICROGLIA; MOUSE; NONHUMAN; PERINATAL PERIOD; PRECURSOR; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; TRANSGENIC MOUSE;

AGE FACTORS; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CEREBRAL CORTEX; DOWN-REGULATION; FEMALE; GENE EXPRESSION; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-4; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; RNA, MESSENGER; UP-REGULATION;

EID: 20244364226     PISSN: 01655728     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-5728(02)00050-4     Document Type: Article

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