Noradrenergic Depletion Potentiates β-Amyloid-Induced Cortical Inflammation: Implications for Alzheimer's Disease

Journal of Neuroscience

Volumn 22, Issue 7, 2002, Pages 2434-2442

  Heneka, Michael T ^a   Galea, Elena ^b   Gavriluyk, Vitaliy ^b   Dumitrescu Ozimek, Lucia ^a   Daeschner, JoAnna ^c   O'Banion, M Kerry ^c   Weinberg, Guy ^b   Klockgether, Thomas ^a   Feinstein, Douglas L ^b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

Alzheimer's disease; Amyloid; Cytokines; Interleukin; Locus ceruleus; Nitric oxide

Indexed keywords

2 BROMO N (2 CHLOROETHYL) N ETHYLBENZYLAMINE; AMYLOID BETA PROTEIN; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CYCLOOXYGENASE 2; INTERLEUKIN 1; INTERLEUKIN 6; ISOPRENALINE; NEUROTOXIN; NITRIC OXIDE SYNTHASE; NORADRENALIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); BENZYLAMINE DERIVATIVE; IMMUNOLOGICAL ADJUVANT; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NOS2 PROTEIN, RAT; PEPTIDE FRAGMENT; TYROSINE 3 MONOOXYGENASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL DEATH; CONTROLLED STUDY; DRUG POTENTIATION; ENCEPHALITIS; GENE EXPRESSION; LOCUS CERULEUS; MALE; MICROGLIA; NERVE CELL; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; ANIMAL; BIOSYNTHESIS; BRAIN CORTEX; CELL COUNT; CHEMICALLY INDUCED DISORDER; DRUG ADMINISTRATION ROUTE; DRUG EFFECT; GENETICS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ADJUVANTS, IMMUNOLOGIC; ADRENERGIC BETA-AGONISTS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; BENZYLAMINES; CELL COUNT; CELL DEATH; CEREBRAL CORTEX; DRUG ADMINISTRATION ROUTES; DRUG SYNERGISM; ENCEPHALITIS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-1; LOCUS COERULEUS; MALE; NEURONS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NOREPINEPHRINE; PEPTIDE FRAGMENTS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TYROSINE 3-MONOOXYGENASE;

EID: 0036546148     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-07-02434.2002     Document Type: Article

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