Nonsteroidal Anti-Inflammatory Drugs and Peroxisome Proliferator-Activated Receptor-γ Agonists Modulate Immunostimulated Processing of Amyloid Precursor Protein through Regulation of β-Secretase

Journal of Neuroscience

Volumn 23, Issue 30, 2003, Pages 9796-9804

  Sastre, Magdalena ^a   Dewachter, Ilse ^b   Landreth, Gary E ^c   Wilson, Timothy M ^d   Klockgether, Thomas ^a   Van Leuven, Fred ^b   Heneka, Michael T ^a  

^a UNIVERSITY OF BONN   (Germany)

^b O and N 06602   (Belgium)

^c CASE WESTERN RESERVE UNIVERSITY   (United States)

^d GLAXOSMITHKLINE   (United States)

Author keywords

Amyloid precursor protein (APP); Amyloid ; BACE1; Cytokine; Ibuprofen; NSAIDs; PPAR

Indexed keywords

AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; COMPLEMENTARY DNA; CYTOKINE; IBUPROFEN; INDOMETACIN; MESSENGER RNA; NONSTEROID ANTIINFLAMMATORY AGENT; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PIOGLITAZONE;

ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; INFLAMMATION; NEUROBLASTOMA CELL; PRIORITY JOURNAL;

EID: 0242609178     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.23-30-09796.2003     Document Type: Article

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