Bone marrow-derived microglia play a critical role in restricting senile plaque formation in Alzheimer's disease

Neuron

Volumn 49, Issue 4, 2006, Pages 489-502

  Simard, Alain R ^a   Soulet, Denis ^a   Gowing, Genevieve ^a   Julien, Jean Pierre ^a   Rivest, Serge ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CD11B ANTIGEN; THYMIDINE KINASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL ACTIVATION; CELL INFILTRATION; CELL MIGRATION; CONTROLLED STUDY; IMMUNOREACTIVITY; MICROGLIA; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENILE PLAQUE; TRANSGENIC MOUSE; TREATMENT OUTCOME;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD46; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; CALCIUM-BINDING PROTEINS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HUMANS; IMAGING, THREE-DIMENSIONAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INDOLES; INJECTIONS, INTRAVENTRICULAR; INTERLEUKIN-1; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; MICROSCOPY, CONFOCAL; PEPTIDE FRAGMENTS; PHAGOCYTOSIS; PRESENILIN-1; RNA, MESSENGER; SENILE PLAQUES; TIME FACTORS; TOLL-LIKE RECEPTOR 2; TUMOR NECROSIS FACTOR-ALPHA; WHOLE-BODY IRRADIATION;

EID: 32344440522     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuron.2006.01.022     Document Type: Article

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