TET-mediated active DNA demethylation: Mechanism, function and beyond

Nature Reviews Genetics

Volumn 18, Issue 9, 2017, Pages 517-534

  Wu, Xiaoji ^a,b,c,d   Zhang, Yi ^a,b,c,d  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b BOSTON CHILDREN S HOSPITAL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; CYTOSINE; DIOXYGENASE; PROTEIN; TET PROTEIN; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG; 5 METHYLCYTOSINE;

BIOCHEMICAL ANALYSIS; BIOLOGICAL FUNCTIONS; CELL DIFFERENTIATION; DEMETHYLATION; DEVELOPMENTAL BIOLOGY; DILUTION; DNA DEMETHYLATION; DNA METHYLATION; DNA REPLICATION; ENZYME ACTIVATION; EXCISION REPAIR; GENE LOCATION; GENOME ANALYSIS; HUMAN; MALIGNANT NEOPLASM; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; NERVE CELL; NERVE FUNCTION; NONHUMAN; OXIDATION KINETICS; OXIDATION REDUCTION STATE; PLURIPOTENT STEM CELL; PREIMPLANTATION EMBRYO; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN STRUCTURE; REGULATORY MECHANISM; REVIEW; RNA PROCESSING; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM;

5-METHYLCYTOSINE; ANIMALS; DIOXYGENASES; DNA METHYLATION; GENE EXPRESSION REGULATION; HUMANS; METABOLIC NETWORKS AND PATHWAYS;

EID: 85027516743     PISSN: 14710056     EISSN: 14710064     Source Type: Journal    
DOI: 10.1038/nrg.2017.33     Document Type: Review

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