5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation

Molecular Cell

Volumn 56, Issue 2, 2014, Pages 286-297

  Hon, Gary C ^a   Song, Chun Xiao ^b   Du, Tingting ^a   Jin, Fulai ^a   Selvaraj, Siddarth ^a   Lee, Ah Young ^a   Yen, Chia An ^a   Ye, Zhen ^a   Mao, Shi Qing ^c   Wang, Bang An ^c   Kuan, Samantha ^a   Edsall, Lee E ^a   Zhao, Boxuan Simen ^b   Xu, Guo Liang ^c   He, Chuan ^b   Ren, Bing ^a,d  

^a LUDWIG INSTITUTE FOR CANCER RESEARCH   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; DIOXYGENASE; TEN ELEVEN TRANSLOCATION 2; TRANSCRIPTOME; UNCLASSIFIED DRUG; 5 METHYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE; DNA BINDING PROTEIN; ONCOPROTEIN; TET1 PROTEIN, MOUSE; TET2 PROTEIN, MOUSE; ZINC FINGER PROTEIN;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA METHYLATION; ENHANCER REGION; GENE EXPRESSION; GENE INDUCTION; MASS SPECTROMETRY; MORPHOGENESIS; MOUSE; NONHUMAN; OXIDATION; ANALOGS AND DERIVATIVES; ANIMAL; CELL LINE; DNA SEQUENCE; GENETICS; KNOCKOUT MOUSE; METABOLISM; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PROMOTER REGION;

MAMMALIA;

5-METHYLCYTOSINE; ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; CELL LINE; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; ENHANCER ELEMENTS, GENETIC; MICE; MICE, KNOCKOUT; OXIDATION-REDUCTION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS; SEQUENCE ANALYSIS, DNA; TRANSCRIPTOME; ZINC FINGERS;

EID: 84908204470     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.08.026     Document Type: Article

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