Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: Its structural basis and implications for active DNA demethylation

Nucleic Acids Research

Volumn 40, Issue 20, 2012, Pages 10203-10214

  Hashimoto, Hideharu ^a   Hong, Samuel ^a   Bhagwat, Ashok S ^b   Zhang, Xing ^a   Cheng, Xiaodong ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBOXYLCYTOSINE; 5 HYDROXYMETHYLURACIL; CYTOSINE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DOUBLE STRANDED DNA; HYDROGEN; SUGAR; THYMINE; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG; URACIL; URACIL DNA GLYCOSIDASE;

ARTICLE; DNA CLEAVAGE; DNA METHYLATION; DNA MODIFICATION; DNA STRUCTURE; ENZYME ACTIVE SITE; ENZYME BINDING; ESCHERICHIA COLI; HYDROGEN BOND; MISMATCH REPAIR; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN DOMAIN; TAUTOMERIZATION;

BIOCATALYSIS; CATALYTIC DOMAIN; CYTOSINE; DNA; HUMANS; MODELS, MOLECULAR; PENTOXYL; THYMINE DNA GLYCOSYLASE;

ESCHERICHIA COLI; MAMMALIA;

EID: 84869044795     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks845     Document Type: Article

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