Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

Science

Volumn 333, Issue 6047, 2011, Pages 1303-1307

  He, Yu Fei ^a   Li, Bin Zhong ^a   Li, Zheng ^a   Liu, Peng ^a   Wang, Yang ^a   Tang, Qingyu ^a   Ding, Jianping ^a   Jia, Yingying ^a   Chen, Zhangcheng ^a   Li, N ^a   Sun, Yan ^b   Li, Xiuxue ^b   Dai, Qing ^c   Song, Chun Xiao ^c   Zhang, Kangling ^d   He, Chuan ^c   Xu, Guo Liang ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^c UNIVERSITY OF CHICAGO   (United States)

^d LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 CARBOXYLCYTOSINE; 5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; CYTOSINE DERIVATIVE; GENOMIC DNA; SHORT HAIRPIN RNA; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE;

CELL ORGANELLE; EMBRYO; ENZYME ACTIVITY; GENETIC ANALYSIS; MAMMAL; METHYLATION; OXIDATION; PROTEIN; RODENT; TRANSLOCATION;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; DNA METHYLATION; DNA MODIFICATION; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EXCISION REPAIR; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; QUADRUPOLE MASS SPECTROMETRY; THIN LAYER CHROMATOGRAPHY;

5-METHYLCYTOSINE; ANIMALS; CELL LINE; CYTOSINE; DNA; DNA METHYLATION; DNA-BINDING PROTEINS; EMBRYONIC STEM CELLS; HEK293 CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; OXIDATION-REDUCTION; PROTO-ONCOGENE PROTEINS; RNA, SMALL INTERFERING; THYMINE DNA GLYCOSYLASE; TRANSFECTION;

MAMMALIA;

EID: 80052495940     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1210944     Document Type: Article

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