-
1
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T. H. & Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926 (1992).
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
2
-
-
0027378582
-
Role for DNA methylation in genomic imprinting
-
Li, E., Beard, C. & Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature 366, 362-365 (1993).
-
(1993)
Nature
, vol.366
, pp. 362-365
-
-
Li, E.1
Beard, C.2
Jaenisch, R.3
-
3
-
-
0035158704
-
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
-
Jackson-Grusby, L. et al. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nature Genet. 27, 31-39 (2001).
-
(2001)
Nature Genet
, vol.27
, pp. 31-39
-
-
Jackson-Grusby, L.1
-
4
-
-
0031662164
-
Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
-
Walsh, C. P., Chaillet, J. R. & Bestor, T. H. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nature Genet. 20, 116-117 (1998).
-
(1998)
Nature Genet
, vol.20
, pp. 116-117
-
-
Walsh, C.P.1
Chaillet, J.R.2
Bestor, T.H.3
-
5
-
-
0035933336
-
The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA
-
Fatemi, M., Hermann, A., Pradhan, S. & Jeltsch, A. The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA. J. Mol. Biol. 309, 1189-1199 (2001).
-
(2001)
J. Mol. Biol
, vol.309
, pp. 1189-1199
-
-
Fatemi, M.1
Hermann, A.2
Pradhan, S.3
Jeltsch, A.4
-
6
-
-
7044245474
-
ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
-
Unoki, M., Nishidate, T. & Nakamura, Y. ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene 23, 7601-7610 (2004).
-
(2004)
Oncogene
, vol.23
, pp. 7601-7610
-
-
Unoki, M.1
Nishidate, T.2
Nakamura, Y.3
-
7
-
-
32344450824
-
Genomic DNA methylation: The mark and its mediators
-
Klose, R. J. & Bird, A. P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31, 89-97 (2006).
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
8
-
-
15744401773
-
Eukaryotic cytosine methyltransferases
-
Goll, M. G. & Bestor, T. H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem. 74, 481-514 (2005).
-
(2005)
Annu. Rev. Biochem
, vol.74
, pp. 481-514
-
-
Goll, M.G.1
Bestor, T.H.2
-
9
-
-
0030770835
-
Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
-
Chuang, L. S. et al. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277, 1996-2000 (1997).
-
(1997)
Science
, vol.277
, pp. 1996-2000
-
-
Chuang, L.S.1
-
10
-
-
33847348016
-
DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
-
Spada, F. et al. DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J. Cell Biol. 176, 565-571 (2007).
-
(2007)
J. Cell Biol
, vol.176
, pp. 565-571
-
-
Spada, F.1
-
11
-
-
33846961476
-
VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization
-
Woo, H. R., Pontes, O., Pikaard, C. S. & Richards, E. J. VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization. Genes Dev. 21, 267-277 (2007).
-
(2007)
Genes Dev
, vol.21
, pp. 267-277
-
-
Woo, H.R.1
Pontes, O.2
Pikaard, C.S.3
Richards, E.J.4
-
12
-
-
0037054539
-
Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry
-
Bonapace, I. M. et al. Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry. J. Cell Biol. 157, 909-914 (2002).
-
(2002)
J. Cell Biol
, vol.157
, pp. 909-914
-
-
Bonapace, I.M.1
-
13
-
-
0037072831
-
Targeted disruption of Np95 gene renders murine embryonic stem cells hypersensitive to DNA damaging agents and DNA replication blocks
-
Muto, M. et al. Targeted disruption of Np95 gene renders murine embryonic stem cells hypersensitive to DNA damaging agents and DNA replication blocks. J. Biol. Chem. 277, 34549-34555 (2002).
-
(2002)
J. Biol. Chem
, vol.277
, pp. 34549-34555
-
-
Muto, M.1
-
14
-
-
33947109937
-
Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing
-
Papait, R. et al. Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing. Mol. Biol. Cell 18, 1098-1106 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 1098-1106
-
-
Papait, R.1
-
15
-
-
0038611015
-
Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice
-
de Boer, E. et al. Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice. Proc. Natl Acad. Sci. USA 100, 7480-7485 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 7480-7485
-
-
de Boer, E.1
-
16
-
-
0042311434
-
Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b
-
Suetake, I., Miyazaki, J., Murakami, C., Takeshima, H. & Tajima, S. Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b. J. Biochem. 133, 737-744 (2003).
-
(2003)
J. Biochem
, vol.133
, pp. 737-744
-
-
Suetake, I.1
Miyazaki, J.2
Murakami, C.3
Takeshima, H.4
Tajima, S.5
-
17
-
-
0026439115
-
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
-
Leonhardt, H., Page, A. W., Weier, H. U. & Bestor, T. H. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71, 865-873 (1992).
-
(1992)
Cell
, vol.71
, pp. 865-873
-
-
Leonhardt, H.1
Page, A.W.2
Weier, H.U.3
Bestor, T.H.4
-
18
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano, M., Bell, D. W., Haber, D. A. & Li, E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257 (1999).
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
19
-
-
33745270104
-
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
-
Tsumura, A. et al. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11, 805-814 (2006).
-
(2006)
Genes Cells
, vol.11
, pp. 805-814
-
-
Tsumura, A.1
-
20
-
-
0035943709
-
Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
-
Bachman, K. E., Rountree, M. R. & Baylin, S. B. Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin. J. Biol. Chem. 276, 32282-32287 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, pp. 32282-32287
-
-
Bachman, K.E.1
Rountree, M.R.2
Baylin, S.B.3
-
21
-
-
0036142089
-
Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro
-
Lin, I. G. et al. Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro. Mol. Cell. Biol. 22, 704-723 (2002).
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 704-723
-
-
Lin, I.G.1
-
22
-
-
33847293264
-
Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
-
Chen, T. et al. Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nature Genet. 39, 391-396 (2007).
-
(2007)
Nature Genet
, vol.39
, pp. 391-396
-
-
Chen, T.1
-
23
-
-
36849082927
-
Major and essential role for DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions
-
Takebayashi, S., Tamura, T., Matsuoka, C. & Okano, M. Major and essential role for DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions. Mol. Cell. Biol. 27, 8243-8258 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 8243-8258
-
-
Takebayashi, S.1
Tamura, T.2
Matsuoka, C.3
Okano, M.4
-
24
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760-1764 (2007).
-
(2007)
Science
, vol.317
, pp. 1760-1764
-
-
Bostick, M.1
-
25
-
-
34347334590
-
Biological functions of DNA methyltransferase 1 require its methyltransferase activity
-
Damelin, M. & Bestor, T. H. Biological functions of DNA methyltransferase 1 require its methyltransferase activity. Mol. Cell. Biol. 27, 3891-3899 (2007).
-
(2007)
Mol. Cell. Biol
, vol.27
, pp. 3891-3899
-
-
Damelin, M.1
Bestor, T.H.2
-
26
-
-
0037083752
-
The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity
-
Pradhan, S. & Kim, G. D. The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity. EMBO J. 21, 779-788 (2002).
-
(2002)
EMBO J
, vol.21
, pp. 779-788
-
-
Pradhan, S.1
Kim, G.D.2
-
27
-
-
12444253985
-
Modulation of DNMT1 activity by ADP-ribose polymers
-
Reale, A. et al. Modulation of DNMT1 activity by ADP-ribose polymers. Oncogene 24, 13-19 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 13-19
-
-
Reale, A.1
-
28
-
-
33751209468
-
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
-
Estève, P. O. et al. Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev. 20, 3089-3103 (2006).
-
(2006)
Genes Dev
, vol.20
, pp. 3089-3103
-
-
Estève, P.O.1
-
29
-
-
20344396373
-
Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein
-
Carlone, D. L. et al. Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein. Mol. Cell. Biol. 25, 4881-4891 (2005).
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 4881-4891
-
-
Carlone, D.L.1
-
30
-
-
0032880930
-
Nuclear organization studied with the help of a hypotonic shift: Its use permits hydrophilic molecules to enter into living cells
-
Koberna, K. et al. Nuclear organization studied with the help of a hypotonic shift: its use permits hydrophilic molecules to enter into living cells. Chromosoma 108, 325-335 (1999).
-
(1999)
Chromosoma
, vol.108
, pp. 325-335
-
-
Koberna, K.1
|