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Volumn 450, Issue 7171, 2007, Pages 908-912

The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNA

Author keywords

[No Author keywords available]

Indexed keywords

DNA; DNA METHYLTRANSFERASE 1; GENE PRODUCT; NP95 PROTEIN; SRA PROTEIN; UNCLASSIFIED DRUG;

EID: 36849072573     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06397     Document Type: Article
Times cited : (1043)

References (30)
  • 1
    • 0026708177 scopus 로고
    • Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
    • Li, E., Bestor, T. H. & Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926 (1992).
    • (1992) Cell , vol.69 , pp. 915-926
    • Li, E.1    Bestor, T.H.2    Jaenisch, R.3
  • 2
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., Beard, C. & Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature 366, 362-365 (1993).
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 3
    • 0035158704 scopus 로고    scopus 로고
    • Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
    • Jackson-Grusby, L. et al. Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation. Nature Genet. 27, 31-39 (2001).
    • (2001) Nature Genet , vol.27 , pp. 31-39
    • Jackson-Grusby, L.1
  • 4
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
    • Walsh, C. P., Chaillet, J. R. & Bestor, T. H. Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nature Genet. 20, 116-117 (1998).
    • (1998) Nature Genet , vol.20 , pp. 116-117
    • Walsh, C.P.1    Chaillet, J.R.2    Bestor, T.H.3
  • 5
    • 0035933336 scopus 로고    scopus 로고
    • The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA
    • Fatemi, M., Hermann, A., Pradhan, S. & Jeltsch, A. The activity of the murine DNA methyltransferase Dnmt1 is controlled by interaction of the catalytic domain with the N-terminal part of the enzyme leading to an allosteric activation of the enzyme after binding to methylated DNA. J. Mol. Biol. 309, 1189-1199 (2001).
    • (2001) J. Mol. Biol , vol.309 , pp. 1189-1199
    • Fatemi, M.1    Hermann, A.2    Pradhan, S.3    Jeltsch, A.4
  • 6
    • 7044245474 scopus 로고    scopus 로고
    • ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain
    • Unoki, M., Nishidate, T. & Nakamura, Y. ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain. Oncogene 23, 7601-7610 (2004).
    • (2004) Oncogene , vol.23 , pp. 7601-7610
    • Unoki, M.1    Nishidate, T.2    Nakamura, Y.3
  • 7
    • 32344450824 scopus 로고    scopus 로고
    • Genomic DNA methylation: The mark and its mediators
    • Klose, R. J. & Bird, A. P. Genomic DNA methylation: the mark and its mediators. Trends Biochem. Sci. 31, 89-97 (2006).
    • (2006) Trends Biochem. Sci , vol.31 , pp. 89-97
    • Klose, R.J.1    Bird, A.P.2
  • 8
    • 15744401773 scopus 로고    scopus 로고
    • Eukaryotic cytosine methyltransferases
    • Goll, M. G. & Bestor, T. H. Eukaryotic cytosine methyltransferases. Annu. Rev. Biochem. 74, 481-514 (2005).
    • (2005) Annu. Rev. Biochem , vol.74 , pp. 481-514
    • Goll, M.G.1    Bestor, T.H.2
  • 9
    • 0030770835 scopus 로고    scopus 로고
    • Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1
    • Chuang, L. S. et al. Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277, 1996-2000 (1997).
    • (1997) Science , vol.277 , pp. 1996-2000
    • Chuang, L.S.1
  • 10
    • 33847348016 scopus 로고    scopus 로고
    • DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells
    • Spada, F. et al. DNMT1 but not its interaction with the replication machinery is required for maintenance of DNA methylation in human cells. J. Cell Biol. 176, 565-571 (2007).
    • (2007) J. Cell Biol , vol.176 , pp. 565-571
    • Spada, F.1
  • 11
    • 33846961476 scopus 로고    scopus 로고
    • VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization
    • Woo, H. R., Pontes, O., Pikaard, C. S. & Richards, E. J. VIM1, a methylcytosine-binding protein required for centromeric heterochromatinization. Genes Dev. 21, 267-277 (2007).
    • (2007) Genes Dev , vol.21 , pp. 267-277
    • Woo, H.R.1    Pontes, O.2    Pikaard, C.S.3    Richards, E.J.4
  • 12
    • 0037054539 scopus 로고    scopus 로고
    • Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry
    • Bonapace, I. M. et al. Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry. J. Cell Biol. 157, 909-914 (2002).
    • (2002) J. Cell Biol , vol.157 , pp. 909-914
    • Bonapace, I.M.1
  • 13
    • 0037072831 scopus 로고    scopus 로고
    • Targeted disruption of Np95 gene renders murine embryonic stem cells hypersensitive to DNA damaging agents and DNA replication blocks
    • Muto, M. et al. Targeted disruption of Np95 gene renders murine embryonic stem cells hypersensitive to DNA damaging agents and DNA replication blocks. J. Biol. Chem. 277, 34549-34555 (2002).
    • (2002) J. Biol. Chem , vol.277 , pp. 34549-34555
    • Muto, M.1
  • 14
    • 33947109937 scopus 로고    scopus 로고
    • Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing
    • Papait, R. et al. Np95 is implicated in pericentromeric heterochromatin replication and in major satellite silencing. Mol. Biol. Cell 18, 1098-1106 (2007).
    • (2007) Mol. Biol. Cell , vol.18 , pp. 1098-1106
    • Papait, R.1
  • 15
    • 0038611015 scopus 로고    scopus 로고
    • Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice
    • de Boer, E. et al. Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice. Proc. Natl Acad. Sci. USA 100, 7480-7485 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 7480-7485
    • de Boer, E.1
  • 16
    • 0042311434 scopus 로고    scopus 로고
    • Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b
    • Suetake, I., Miyazaki, J., Murakami, C., Takeshima, H. & Tajima, S. Distinct enzymatic properties of recombinant mouse DNA methyltransferases Dnmt3a and Dnmt3b. J. Biochem. 133, 737-744 (2003).
    • (2003) J. Biochem , vol.133 , pp. 737-744
    • Suetake, I.1    Miyazaki, J.2    Murakami, C.3    Takeshima, H.4    Tajima, S.5
  • 17
    • 0026439115 scopus 로고
    • A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei
    • Leonhardt, H., Page, A. W., Weier, H. U. & Bestor, T. H. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 71, 865-873 (1992).
    • (1992) Cell , vol.71 , pp. 865-873
    • Leonhardt, H.1    Page, A.W.2    Weier, H.U.3    Bestor, T.H.4
  • 18
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano, M., Bell, D. W., Haber, D. A. & Li, E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99, 247-257 (1999).
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 19
    • 33745270104 scopus 로고    scopus 로고
    • Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
    • Tsumura, A. et al. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b. Genes Cells 11, 805-814 (2006).
    • (2006) Genes Cells , vol.11 , pp. 805-814
    • Tsumura, A.1
  • 20
    • 0035943709 scopus 로고    scopus 로고
    • Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
    • Bachman, K. E., Rountree, M. R. & Baylin, S. B. Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin. J. Biol. Chem. 276, 32282-32287 (2001).
    • (2001) J. Biol. Chem , vol.276 , pp. 32282-32287
    • Bachman, K.E.1    Rountree, M.R.2    Baylin, S.B.3
  • 21
    • 0036142089 scopus 로고    scopus 로고
    • Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro
    • Lin, I. G. et al. Murine de novo methyltransferase Dnmt3a demonstrates strand asymmetry and site preference in the methylation of DNA in vitro. Mol. Cell. Biol. 22, 704-723 (2002).
    • (2002) Mol. Cell. Biol , vol.22 , pp. 704-723
    • Lin, I.G.1
  • 22
    • 33847293264 scopus 로고    scopus 로고
    • Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells
    • Chen, T. et al. Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. Nature Genet. 39, 391-396 (2007).
    • (2007) Nature Genet , vol.39 , pp. 391-396
    • Chen, T.1
  • 23
    • 36849082927 scopus 로고    scopus 로고
    • Major and essential role for DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions
    • Takebayashi, S., Tamura, T., Matsuoka, C. & Okano, M. Major and essential role for DNA methylation mark in mouse embryogenesis and stable association of DNMT1 with newly replicated regions. Mol. Cell. Biol. 27, 8243-8258 (2007).
    • (2007) Mol. Cell. Biol , vol.27 , pp. 8243-8258
    • Takebayashi, S.1    Tamura, T.2    Matsuoka, C.3    Okano, M.4
  • 24
    • 34648833002 scopus 로고    scopus 로고
    • UHRF1 plays a role in maintaining DNA methylation in mammalian cells
    • Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760-1764 (2007).
    • (2007) Science , vol.317 , pp. 1760-1764
    • Bostick, M.1
  • 25
    • 34347334590 scopus 로고    scopus 로고
    • Biological functions of DNA methyltransferase 1 require its methyltransferase activity
    • Damelin, M. & Bestor, T. H. Biological functions of DNA methyltransferase 1 require its methyltransferase activity. Mol. Cell. Biol. 27, 3891-3899 (2007).
    • (2007) Mol. Cell. Biol , vol.27 , pp. 3891-3899
    • Damelin, M.1    Bestor, T.H.2
  • 26
    • 0037083752 scopus 로고    scopus 로고
    • The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity
    • Pradhan, S. & Kim, G. D. The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity. EMBO J. 21, 779-788 (2002).
    • (2002) EMBO J , vol.21 , pp. 779-788
    • Pradhan, S.1    Kim, G.D.2
  • 27
    • 12444253985 scopus 로고    scopus 로고
    • Modulation of DNMT1 activity by ADP-ribose polymers
    • Reale, A. et al. Modulation of DNMT1 activity by ADP-ribose polymers. Oncogene 24, 13-19 (2005).
    • (2005) Oncogene , vol.24 , pp. 13-19
    • Reale, A.1
  • 28
    • 33751209468 scopus 로고    scopus 로고
    • Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
    • Estève, P. O. et al. Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication. Genes Dev. 20, 3089-3103 (2006).
    • (2006) Genes Dev , vol.20 , pp. 3089-3103
    • Estève, P.O.1
  • 29
    • 20344396373 scopus 로고    scopus 로고
    • Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein
    • Carlone, D. L. et al. Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding protein. Mol. Cell. Biol. 25, 4881-4891 (2005).
    • (2005) Mol. Cell. Biol , vol.25 , pp. 4881-4891
    • Carlone, D.L.1
  • 30
    • 0032880930 scopus 로고    scopus 로고
    • Nuclear organization studied with the help of a hypotonic shift: Its use permits hydrophilic molecules to enter into living cells
    • Koberna, K. et al. Nuclear organization studied with the help of a hypotonic shift: its use permits hydrophilic molecules to enter into living cells. Chromosoma 108, 325-335 (1999).
    • (1999) Chromosoma , vol.108 , pp. 325-335
    • Koberna, K.1


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