-
1
-
-
66149146320
-
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M. et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935 (2009).
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
-
2
-
-
79956323623
-
Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz, G. et al. Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473, 398-402 (2011).
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
-
3
-
-
79956308473
-
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells
-
Pastor, W. A. et al. Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. Nature 473, 394-397 (2011).
-
(2011)
Nature
, vol.473
, pp. 394-397
-
-
Pastor, W.A.1
-
4
-
-
79955948324
-
Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
-
Xu, Y. et al. Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells. Mol. Cell 42, 451-464 (2011).
-
(2011)
Mol. Cell
, vol.42
, pp. 451-464
-
-
Xu, Y.1
-
5
-
-
79956292024
-
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
-
Wu, H. et al. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells. Nature 473, 389-393 (2011).
-
(2011)
Nature
, vol.473
, pp. 389-393
-
-
Wu, H.1
-
6
-
-
77956189495
-
Role of Tet proteins in 5mC to 5hmC conversion ES-cell self-renewal and inner cell mass specification
-
Ito, S. et al. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature 466, 1129-1133 (2010).
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
-
7
-
-
0036898933
-
Diverse regulationof protein function by O-GlcNAc: A nuclear and cytoplasmic carbohydrate post-translational modification
-
Vosseller, K., Sakabe, K.,Wells, L.&Hart, G. W. Diverse regulationof protein function by O-GlcNAc: a nuclear and cytoplasmic carbohydrate post-translational modification. Curr. Opin. Chem. Biol. 6, 851-857 (2002).
-
(2002)
Curr. Opin. Chem. Biol.
, vol.6
, pp. 851-857
-
-
Vosseller, K.1
Sakabe, K.2
Wells, L.3
Hart, G.W.4
-
8
-
-
0030959555
-
Dynamic glycosylation of nuclear and cytosolic proteins Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats
-
Kreppel, L. K., Blomberg, M. A. & Hart, G. W. Dynamic glycosylation of nuclear and cytosolic proteins. Cloning and characterization of a unique O-GlcNAc transferase with multiple tetratricopeptide repeats. J. Biol. Chem. 272, 9308-9315 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 9308-9315
-
-
Kreppel, L.K.1
Blomberg, M.A.2
Hart, G.W.3
-
9
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu, T. P. et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477, 606-610 (2011).
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
-
10
-
-
54349112556
-
Structural insights into mechanism and specificity of O-GlcNAc transferase
-
Clarke, A. J. et al. Structural insights into mechanism and specificity of O-GlcNAc transferase. EMBO J. 27, 2780-2788 (2008).
-
(2008)
EMBO J.
, vol.27
, pp. 2780-2788
-
-
Clarke, A.J.1
-
11
-
-
46449085222
-
Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation
-
Martinez-Fleites, C. et al. Structure of an O-GlcNAc transferase homolog provides insight into intracellular glycosylation. Nature Struct.Mol. Biol. 15, 764-765(2008).
-
(2008)
Nature Struct.Mol. Biol.
, vol.15
, pp. 764-765
-
-
Martinez-Fleites, C.1
-
12
-
-
79251611901
-
Structure of human O-GlcNAc transferaseand its complex with a peptide substrate
-
Lazarus,M. B., Nam, Y., Jiang, J., Sliz, P. & Walker, S. Structure of human O-GlcNAc transferaseand its complex with a peptide substrate.Nature469, 564-567(2011).
-
(2011)
Nature
, vol.469
, pp. 564-567
-
-
Lazarus, M.B.1
Nam, Y.2
Jiang, J.3
Sliz, P.4
Walker, S.5
-
13
-
-
53849113697
-
Base J: Discovery, biosyn thesis, and possible functions
-
Borst, P. & Sabatini, R. Base J: discovery, biosynthesis, and possible functions. Annu. Rev. Microbiol. 62, 235-251 (2008).
-
(2008)
Annu. Rev. Microbiol.
, vol.62
, pp. 235-251
-
-
Borst, P.1
Sabatini, R.2
-
14
-
-
80054818714
-
Modificationof histonesby sugar b-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated
-
Zhang,S.,Roche,K.,Nasheuer, H. P.&Lowndes,N. F.Modificationof histonesby sugar b-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated. J. Biol. Chem. 286, 37483-37495 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 37483-37495
-
-
Zhang, S.1
Roche, K.2
Nasheuer, H.P.3
Lowndes, N.F.4
-
15
-
-
84355161950
-
GlcNAcylation of histone H2B facilitates its monoubiquitination
-
Fujiki, R. et al. GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature 480, 557-560 (2011).
-
(2011)
Nature
, vol.480
, pp. 557-560
-
-
Fujiki, R.1
-
16
-
-
78650447665
-
B-N-acetylglucosamine (O-GlcNAc) is part of the histone code
-
Sakabe, K., Wang, Z. & Hart, G. W. b-N-acetylglucosamine (O-GlcNAc) is part of the histone code. Proc. Natl Acad. Sci. USA 107, 19915-19920 (2010).
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 19915-19920
-
-
Sakabe, K.1
Wang, Z.2
Hart, G.W.3
-
17
-
-
84859512121
-
B-N-Acetylglucosamine (O-GlcNAc) is a novel regulator of mitosisspecific phosphorylationson histoneH3
-
Fong, J. J. et al. b-N-Acetylglucosamine (O-GlcNAc) is a novel regulator of mitosisspecific phosphorylationson histoneH3. J. Biol.Chem.287,12195- 12203(2012).
-
(2012)
J. Biol.Chem.
, vol.287
, pp. 12195-12203
-
-
Fong, J.J.1
-
18
-
-
79551661274
-
O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1
-
Capotosti, F. et al. O-GlcNAc transferase catalyzes site-specific proteolysis of HCF-1. Cell 144, 376-388 (2011).
-
(2011)
Cell
, vol.144
, pp. 376-388
-
-
Capotosti, F.1
-
19
-
-
0037067659
-
Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: Coupling protein O-GlcNAcylation to transcriptional repression
-
Yang, X., Zhang, F. & Kudlow, J. E. Recruitment of O-GlcNAc transferase to promoters by corepressor mSin3A: coupling protein O-GlcNAcylation to transcriptional repression. Cell 110, 69-80 (2002).
-
(2002)
Cell
, vol.110
, pp. 69-80
-
-
Yang, X.1
Zhang, F.2
Kudlow, J.E.3
-
20
-
-
0033527739
-
Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats
-
Kreppel, L. K. & Hart, G. W. Regulation of a cytosolic and nuclear O-GlcNAc transferase. Role of the tetratricopeptide repeats. J. Biol. Chem. 274, 32015-32022 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32015-32022
-
-
Kreppel, L.K.1
Hart, G.W.2
-
21
-
-
0037648473
-
Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase
-
Iyer, S. P., Akimoto, Y. & Hart, G. W. Identification and cloning of a novel family of coiled-coil domain proteins that interact with O-GlcNAc transferase. J. Biol. Chem. 278, 5399-5409 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 5399-5409
-
-
Iyer, S.P.1
Akimoto, Y.2
Hart, G.W.3
-
22
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen, T. S. et al. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448, 553-560 (2007).
-
(2007)
Nature
, vol.448
, pp. 553-560
-
-
Mikkelsen, T.S.1
-
23
-
-
83855163995
-
Uncovering the role of 5-hydroxymethylcytosine in the epigenome
-
Branco, M. R., Ficz, G.&Reik, W.Uncovering the role of 5-hydroxymethylcytosine in the epigenome. Nature Rev. Genet. 13, 7-13 (2012).
-
(2012)
Nature Rev. Genet.
, vol.13
, pp. 7-13
-
-
Branco, M.R.1
Ficz, G.2
Reik, W.3
-
24
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
-
Iqbal, K., Jin, S. G., Pfeifer, G. P. & Szabo, P. E. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl Acad. Sci. USA 108, 3642-3647 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
25
-
-
80054097425
-
Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue, A. & Zhang, Y. Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science 334, 194 (2011).
-
(2011)
Science
, vol.334
, Issue.194
-
-
Inoue, A.1
Zhang, Y.2
-
26
-
-
79954457998
-
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
-
Wu, H. et al. Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells. Genes Dev. 25, 679-684 (2011).
-
(2011)
Genes Dev.
, vol.25
, pp. 679-684
-
-
Wu, H.1
-
27
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams, K. et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473, 343-348 (2011).
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
-
28
-
-
78049390185
-
O-GlcNAc transferase regulates mitotic chromatin dynamics
-
Sakabe, K. & Hart, G. W. O-GlcNAc transferase regulates mitotic chromatin dynamics. J. Biol. Chem. 285, 34460-34468 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 34460-34468
-
-
Sakabe, K.1
Hart, G.W.2
-
29
-
-
67650076327
-
Essential role of the glycosyltransferase sxc/Ogt in polycomb repression
-
Gambetta, M. C., Oktaba, K. & Muller, J. Essential role of the glycosyltransferase sxc/Ogt in polycomb repression. Science 325, 93-96 (2009).
-
(2009)
Science
, vol.325
, pp. 93-96
-
-
Gambetta, M.C.1
Oktaba, K.2
Muller, J.3
-
30
-
-
69449092638
-
Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc)
-
Sinclair, D. A. et al. Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc). Proc. Natl Acad. Sci. USA 106, 13427-13432 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 13427-13432
-
-
Sinclair, D.A.1
-
31
-
-
34250782684
-
Purification and analysis of histones
-
Shechter, D., Dormann, H. L., Allis, C. D. & Hake, S. B. Extraction, purification and analysis of histones. Nature Protocols 2, 1445-1457 (2007).
-
(2007)
Nature Protocols
, vol.2
, pp. 1445-1457
-
-
Shechter, D.1
Dormann, H.L.2
Allis, C.D.3
Extraction, B.H.S.4
-
32
-
-
67349189942
-
GlcNAcylation of a histone methyltransferase in retinoic-acidinduced granulopoiesis
-
Fujiki, R. et al. GlcNAcylation of a histone methyltransferase in retinoic-acidinduced granulopoiesis. Nature 459, 455-459 (2009).
-
(2009)
Nature
, vol.459
, pp. 455-459
-
-
Fujiki, R.1
-
33
-
-
33947109881
-
Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes
-
Robinson, K. A., Ball, L. E. & Buse, M. G. Reduction of O-GlcNAc protein modification does not prevent insulin resistance in 3T3-L1 adipocytes. Am. J. Physiol. Endocrinol. Metab. 292, E884-E890 (2007).
-
(2007)
Am. J. Physiol. Endocrinol. Metab.
, vol.292
-
-
Robinson, K.A.1
Ball, L.E.2
Buse, M.G.3
-
34
-
-
78650175023
-
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
-
Ko, M. et al. Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2. Nature 468, 839-843 (2010).
-
(2010)
Nature
, vol.468
, pp. 839-843
-
-
Ko, M.1
-
35
-
-
78951474461
-
MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1
-
Yang, Z. et al. MicroRNA hsa-miR-138 inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells through adenovirus EID-1. Stem Cells Dev. 20, 259-267 (2011).
-
(2011)
Stem Cells Dev.
, vol.20
, pp. 259-267
-
-
Yang, Z.1
|