-
1
-
-
78049414227
-
Epigenetic reprogramming in plant and animal development
-
Feng, S., Jacobsen, S. E. & Reik, W. Epigenetic reprogramming in plant and animal development. Science 330, 622-627 (2010
-
(2010)
Science
, vol.330
, pp. 622-627
-
-
Feng, S.1
Jacobsen, S.E.2
Reik, W.3
-
2
-
-
0034625064
-
Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a
-
Ramsahoye, B. H. et al. Non-CpG methylation is prevalent in embryonic stem cells and may be mediated by DNA methyltransferase 3a. Proc. Natl Acad. Sci. USA 97, 5237-5242 (2000
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 5237-5242
-
-
Ramsahoye, B.H.1
-
3
-
-
84855281409
-
Genomic distribution and inter-sample variation of non-CpG methylation across human cell types
-
Ziller, M. J. et al. Genomic distribution and inter-sample variation of non-CpG methylation across human cell types. PLoS Genet. 7, e1002389 (2011
-
(2011)
PLoS Genet
, vol.7
-
-
Ziller, M.J.1
-
4
-
-
0033615717
-
DNA methyltransferases DNMT3A and DNMT3B are essential for de novo methylation and mammalian development
-
Okano, M., Bell, D. W., Haber, D. A. & Li, E. DNA methyltransferases DNMT3A and DNMT3B are essential for de novo methylation and mammalian development. Cell 99, 247-257 (1999
-
(1999)
Cell
, vol.99
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
5
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li, E., Bestor, T. H. & Jaenisch, R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 69, 915-926 (1992
-
(1992)
Cell
, vol.69
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
6
-
-
79956330964
-
CpG islands and the regulation of transcription
-
Deaton, A. M. & Bird, A. CpG islands and the regulation of transcription. Genes Dev. 25, 1010-1022 (2011
-
(2011)
Genes Dev
, vol.25
, pp. 1010-1022
-
-
Deaton, A.M.1
Bird, A.2
-
7
-
-
0016439429
-
DNA modification mechanisms and gene activity during development
-
Holliday, R. & Pugh, J. E. DNA modification mechanisms and gene activity during development. Science 187, 226-232 (1975
-
(1975)
Science
, vol.187
, pp. 226-232
-
-
Holliday, R.1
Pugh, J.E.2
-
8
-
-
0016692220
-
X inactivation, differentiation, and DNA methylation
-
Riggs, A. D. X inactivation, differentiation, and DNA methylation. Cytogenet. Cell Genet. 14, 9-25 (1975
-
(1975)
Cytogenet. Cell Genet
, vol.14
, pp. 9-25
-
-
Riggs, A.D.1
-
9
-
-
77249137168
-
Principles and challenges of genomewide DNA methylation analysis
-
Laird, P. W. Principles and challenges of genomewide DNA methylation analysis. Nature Rev. Genet. 11, 191-203 (2010
-
(2010)
Nature Rev. Genet
, vol.11
, pp. 191-203
-
-
Laird, P.W.1
-
10
-
-
84859910536
-
A unique regulatory phase of DNA methylation in the early mammalian embryo
-
Smith, Z. D. et al. A unique regulatory phase of DNA methylation in the early mammalian embryo. Nature 484, 339-344 (2012
-
(2012)
Nature
, vol.484
, pp. 339-344
-
-
Smith, Z.D.1
-
11
-
-
78049419464
-
Orphan CpG islands identify numerous conserved promoters in the mammalian genome
-
Illingworth, R. S. et al. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. PLoS Genet. 6, e1001134 (2010
-
(2010)
PLoS Genet
, vol.6
-
-
Illingworth, R.S.1
-
12
-
-
0027960055
-
SP1 sites in the mouse Aprt gene promoter are required to prevent methylation of the CpG island
-
Macleod, D., Charlton, J., Mullins, J. & Bird, A. P. SP1 sites in the mouse Aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 8, 2282-2292 (1994
-
(1994)
Genes Dev
, vol.8
, pp. 2282-2292
-
-
MacLeod, D.1
Charlton, J.2
Mullins, J.3
Bird, A.P.4
-
13
-
-
0028104109
-
SP1 elements protect a CpG island from de novo methylation
-
Brandeis, M. et al. SP1 elements protect a CpG island from de novo methylation. Nature 371, 435-438 (1994
-
(1994)
Nature
, vol.371
, pp. 435-438
-
-
Brandeis, M.1
-
14
-
-
80054994283
-
Identification of genetic elements that autonomously determine DNA methylation states
-
Lienert, F. et al. Identification of genetic elements that autonomously determine DNA methylation states. Nature Genet. 43, 1091-1097 (2011
-
(2011)
Nature Genet
, vol.43
, pp. 1091-1097
-
-
Lienert, F.1
-
15
-
-
84355163093
-
DNA-binding factors shape the mouse methylome at distal regulatory regions
-
Stadler, M. B. et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature 480, 490-495 (2011
-
(2011)
Nature
, vol.480
, pp. 490-495
-
-
Stadler, M.B.1
-
16
-
-
77951116072
-
CpG islands influence chromatin structure via the CpG-binding protein CFP1
-
Thomson, J. P. et al. CpG islands influence chromatin structure via the CpG-binding protein CFP1. Nature 464, 1082-1086 (2010
-
(2010)
Nature
, vol.464
, pp. 1082-1086
-
-
Thomson, J.P.1
-
17
-
-
84864752375
-
CFP1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells
-
Clouaire, T. et al. CFP1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells. Genes Dev. 26, 1714-1728 (2012
-
(2012)
Genes Dev
, vol.26
, pp. 1714-1728
-
-
Clouaire, T.1
-
18
-
-
44949221144
-
MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression
-
Erfurth, F. E. et al. MLL protects CpG clusters from methylation within the Hoxa9 gene, maintaining transcript expression. Proc. Natl Acad. Sci. USA 105, 7517-7522 (2008
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 7517-7522
-
-
Erfurth, F.E.1
-
19
-
-
70449099301
-
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
-
Otani, J. et al. Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain. EMBO Rep. 10, 1235-1241 (2009
-
(2009)
EMBO Rep
, vol.10
, pp. 1235-1241
-
-
Otani, J.1
-
20
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
Ooi, S. K. et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 448, 714-717 (2007
-
(2007)
Nature
, vol.448
, pp. 714-717
-
-
Ooi, S.K.1
-
21
-
-
78649281582
-
Changes in H2A.Z occupancy & DNA methylation during B cell lymphomagenesis
-
Conerly, M. L. et al. Changes in H2A.Z occupancy & DNA methylation during B cell lymphomagenesis. Genome Res. 20, 1383-1390 (2010
-
(2010)
Genome Res
, vol.20
, pp. 1383-1390
-
-
Conerly, M.L.1
-
22
-
-
84859261580
-
Gene reactivation by 5 aza 2Ŷ deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions
-
Yang, X. et al. Gene reactivation by 5 aza 2Ŷ deoxycytidine-induced demethylation requires SRCAP-mediated H2A.Z insertion to establish nucleosome depleted regions. PLoS Genet. 8, e1002604 (2012
-
(2012)
PLoS Genet
, vol.8
-
-
Yang, X.1
-
23
-
-
84861883921
-
Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-Talk
-
Brinkman, A. B. et al. Sequential ChIP-bisulfite sequencing enables direct genome-scale investigation of chromatin and DNA methylation cross-Talk. Genome Res. 22, 1128-1138 (2012
-
(2012)
Genome Res
, vol.22
, pp. 1128-1138
-
-
Brinkman, A.B.1
-
24
-
-
77958481159
-
Nucleosome-interacting proteins regulated by DNA and histone methylation
-
Bartke, T. et al. Nucleosome-interacting proteins regulated by DNA and histone methylation. Cell 143, 470-484 (2010
-
(2010)
Cell
, vol.143
, pp. 470-484
-
-
Bartke, T.1
-
25
-
-
50849107031
-
Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus
-
Lindroth, A. M. et al. Antagonism between DNA and H3K27 methylation at the imprinted Rasgrf1 locus. PLoS Genet. 4, e1000145 (2008
-
(2008)
PLoS Genet
, vol.4
-
-
Lindroth, A.M.1
-
26
-
-
84863986133
-
Functions of DNA methylation: Islands, start sites, gene bodies and beyond
-
Jones, P. A. Functions of DNA methylation: Islands, start sites, gene bodies and beyond. Nature Rev. Genet. 13, 484-492 (2012
-
(2012)
Nature Rev. Genet
, vol.13
, pp. 484-492
-
-
Jones, P.A.1
-
27
-
-
84859087611
-
R loop formation is a distinctive characteristic of unmethylated human CpG island promoters
-
Ginno, P. A., Lott, P. L., Christensen, H. C., Korf, I. & Chedin, F. R loop formation is a distinctive characteristic of unmethylated human CpG island promoters. Mol. Cell 45, 814-825 (2012
-
(2012)
Mol. Cell
, vol.45
, pp. 814-825
-
-
Ginno, P.A.1
Lott, P.L.2
Christensen, H.C.3
Korf, I.4
Chedin, F.5
-
28
-
-
38449104412
-
On the enzymatic properties of DNMT1: Specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme
-
Jeltsch, A. On the enzymatic properties of DNMT1: Specificity, processivity, mechanism of linear diffusion and allosteric regulation of the enzyme. Epigenetics 1, 63-66 (2006
-
(2006)
Epigenetics
, vol.1
, pp. 63-66
-
-
Jeltsch, A.1
-
29
-
-
79952053850
-
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation
-
Song, J., Rechkoblit, O., Bestor, T. H. & Patel, D. J. Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science 331, 1036-1040 (2011
-
(2011)
Science
, vol.331
, pp. 1036-1040
-
-
Song, J.1
Rechkoblit, O.2
Bestor, T.H.3
Patel, D.J.4
-
30
-
-
0028140270
-
Characterization of a negative retinoic acid response element in the murine OCT4 promoter
-
Schoorlemmer, J. et al. Characterization of a negative retinoic acid response element in the murine OCT4 promoter. Mol. Cell. Biol. 14, 1122-1136 (1994
-
(1994)
Mol. Cell. Biol
, vol.14
, pp. 1122-1136
-
-
Schoorlemmer, J.1
-
31
-
-
0035890090
-
LSH a member of the SNF2 family, is required for genome-wide methylation
-
Dennis, K., Fan, T., Geiman, T., Yan, Q. & Muegge, K. LSH, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev. 15, 2940-2944 (2001
-
(2001)
Genes Dev
, vol.15
, pp. 2940-2944
-
-
Dennis, K.1
Fan, T.2
Geiman, T.3
Yan, Q.4
Muegge, K.5
-
32
-
-
31444436545
-
LSH is involved in de novo methylation of DNA
-
Zhu, H. et al. LSH is involved in de novo methylation of DNA. EMBO J. 25, 335-345 (2006
-
(2006)
EMBO J
, vol.25
, pp. 335-345
-
-
Zhu, H.1
-
33
-
-
37549061829
-
LSH cooperates with DNA methyltransferases to repress transcription
-
Myant, K. & Stancheva, I. LSH cooperates with DNA methyltransferases to repress transcription. Mol. Cell. Biol. 28, 215-226 (2008
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 215-226
-
-
Myant, K.1
Stancheva, I.2
-
34
-
-
78651521292
-
LSH and G9A/GLP complex are required for developmentally programmed DNA methylation
-
Myant, K. et al. LSH and G9A/GLP complex are required for developmentally programmed DNA methylation. Genome Res. 21, 83-94 (2011
-
(2011)
Genome Res
, vol.21
, pp. 83-94
-
-
Myant, K.1
-
35
-
-
55549145072
-
De novo DNA methylation promoted by G9A prevents reprogramming of embryonically silenced genes
-
Epsztejn-Litman, S. et al. De novo DNA methylation promoted by G9A prevents reprogramming of embryonically silenced genes. Nature Struct. Mol. Biol. 15, 1176-1183 (2008
-
(2008)
Nature Struct Mol. Iol
, vol.15
, pp. 1176-1183
-
-
Epsztejn-Litman, S.1
-
36
-
-
54349114603
-
DNA methylation in ES cells requires the lysine methyltransferase G9A but not its catalytic activity
-
Dong, K. B. et al. DNA methylation in ES cells requires the lysine methyltransferase G9A but not its catalytic activity. EMBO J. 27, 2691-2701 (2008
-
(2008)
EMBO J
, vol.27
, pp. 2691-2701
-
-
Dong, K.B.1
-
37
-
-
0041624239
-
Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: B mammalian cell culture model of gene variegation
-
Ayyanathan, K. et al. Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: B mammalian cell culture model of gene variegation. Genes Dev. 17, 1855-1869 (2003
-
(2003)
Genes Dev
, vol.17
, pp. 1855-1869
-
-
Ayyanathan, K.1
-
38
-
-
10744230544
-
UV39H mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
-
Lehnertz, B. et al. SUV39H mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr. Biol. 13, 1192-1200 (2003
-
(2003)
Curr. Biol
, vol.13
, pp. 1192-1200
-
-
Lehnertz, B.1
-
39
-
-
0033547330
-
Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene
-
Xu, G. L. et al. Chromosome instability and immunodeficiency syndrome caused by mutations in a DNA methyltransferase gene. Nature 402, 187-191 (1999
-
(1999)
Nature
, vol.402
, pp. 187-191
-
-
Xu, G.L.1
-
40
-
-
4744366752
-
The PWWP domain of DNMT3A and DNMT3B is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin
-
Chen, T., Tsujimoto, N. & Li, E. The PWWP domain of DNMT3A and DNMT3B is required for directing DNA methylation to the major satellite repeats at pericentric heterochromatin. Mol. Cell. Biol. 24, 9048-9058 (2004
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 9048-9058
-
-
Chen, T.1
Tsujimoto, N.2
Li, E.3
-
41
-
-
68749117667
-
NMT3B interacts with constitutive centromere protein CENP C to modulate DNA methylation and the histone code at centromeric regions
-
Gopalakrishnan, S., Sullivan, B. A., Trazzi, S., Della Valle, G. & Robertson, K. D. DNMT3B interacts with constitutive centromere protein CENP C to modulate DNA methylation and the histone code at centromeric regions. Hum. Mol. Genet. 18, 3178-3193 (2009
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 3178-3193
-
-
Gopalakrishnan, S.1
Sullivan, B.A.2
Trazzi, S.3
Della Valle, G.4
Robertson, K.D.5
-
42
-
-
37449015481
-
CENP B controls centromere formation depending on the chromatin context
-
Okada, T. et al. CENP B controls centromere formation depending on the chromatin context. Cell 131, 1287-1300 (2007
-
(2007)
Cell
, vol.131
, pp. 1287-1300
-
-
Okada, T.1
-
43
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston, R. H. et al. Initial sequencing and comparative analysis of the mouse genome. Nature 420, 520-562 (2002
-
(2002)
Nature
, vol.420
, pp. 520-562
-
-
Waterston, R.H.1
-
44
-
-
0036135014
-
Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements
-
Liang, G. et al. Cooperativity between DNA methyltransferases in the maintenance methylation of repetitive elements. Mol. Cell. Biol. 22, 480-491 (2002
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 480-491
-
-
Liang, G.1
-
45
-
-
67349170854
-
Embryonic stem cells use ZFP809 to silence retroviral DNAs
-
Wolf, D. & Goff, S. P. Embryonic stem cells use ZFP809 to silence retroviral DNAs. Nature 458, 1201-1204 (2009
-
(2009)
Nature
, vol.458
, pp. 1201-1204
-
-
Wolf, D.1
Goff, S.P.2
-
46
-
-
74549116659
-
KAP1 controls endogenous retroviruses in embryonic stem cells
-
Rowe, H. M. et al. KAP1 controls endogenous retroviruses in embryonic stem cells. Nature 463, 237-240 (2010
-
(2010)
Nature
, vol.463
, pp. 237-240
-
-
Rowe, H.M.1
-
47
-
-
34848819391
-
TRIM28 mediates primer binding site-Targeted silencing of murine leukemia virus in embryonic cells
-
Wolf, D. & Goff, S. P. TRIM28 mediates primer binding site-Targeted silencing of murine leukemia virus in embryonic cells. Cell 131, 46-57 (2007
-
(2007)
Cell
, vol.131
, pp. 46-57
-
-
Wolf, D.1
Goff, S.P.2
-
48
-
-
36348930084
-
The Kruppel-Associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis
-
Wiznerowicz, M. et al. The Kruppel-Associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis. J. Biol. Chem. 282, 34535-34541 (2007
-
(2007)
J. Biol. Chem
, vol.282
, pp. 34535-34541
-
-
Wiznerowicz, M.1
-
49
-
-
77950862656
-
Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
-
Matsui, T. et al. Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature 464, 927-931 (2010
-
(2010)
Nature
, vol.464
, pp. 927-931
-
-
Matsui, T.1
-
50
-
-
79957844585
-
DNA methylation and SETDB1/ H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs
-
Karimi, M. M. et al. DNA methylation and SETDB1/ H3K9me3 regulate predominantly distinct sets of genes, retroelements, and chimeric transcripts in mESCs. Cell Stem Cell 8, 676-687 (2011
-
(2011)
Cell Stem Cell
, vol.8
, pp. 676-687
-
-
Karimi, M.M.1
-
51
-
-
79955042533
-
Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing
-
Leung, D. C. et al. Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing. Proc. Natl Acad. Sci. USA 108, 5718-5723 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 5718-5723
-
-
Leung, D.C.1
-
52
-
-
77957901287
-
Dynamic instability of genomic methylation patterns in pluripotent stem cells
-
Ooi, S. K. et al. Dynamic instability of genomic methylation patterns in pluripotent stem cells. Epigenet. Chromat. 3, 17 (2010
-
(2010)
Epigenet. Chromat
, vol.3
, pp. 17
-
-
Ooi, S.K.1
-
53
-
-
78549247463
-
L1 retrotransposition in neurons is modulated by MeCP2
-
Muotri, A. R. et al. L1 retrotransposition in neurons is modulated by MeCP2. Nature 468, 443-446 (2010
-
(2010)
Nature
, vol.468
, pp. 443-446
-
-
Muotri, A.R.1
-
54
-
-
0031837109
-
Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
-
Jones, P. L. et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nature Genet. 19, 187-191 (1998
-
(1998)
Nature Genet
, vol.19
, pp. 187-191
-
-
Jones, P.L.1
-
55
-
-
0032574977
-
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
-
Nan, X. et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389 (1998
-
(1998)
Nature
, vol.393
, pp. 386-389
-
-
Nan, X.1
-
56
-
-
0020048308
-
De novo methylation and expression of retroviral genomes during mouse embryogenesis
-
Jahner, D. et al. De novo methylation and expression of retroviral genomes during mouse embryogenesis. Nature 298, 623-628 (1982
-
(1982)
Nature
, vol.298
, pp. 623-628
-
-
Jahner, D.1
-
57
-
-
0011078712
-
De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells
-
Stewart, C. L., Stuhlmann, H., Jahner, D. & Jaenisch, R. De novo methylation, expression, and infectivity of retroviral genomes introduced into embryonal carcinoma cells. Proc. Natl Acad. Sci. USA 79, 4098-4102 (1982
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 4098-4102
-
-
Stewart, C.L.1
Stuhlmann, H.2
Jahner, D.3
Jaenisch, R.4
-
58
-
-
84655164284
-
De novo DNA methylation: B germ cell perspective
-
Smallwood, S. A. & Kelsey, G. De novo DNA methylation: B germ cell perspective. Trends Genet. 28, 33-42 (2012
-
(2012)
Trends Genet
, vol.28
, pp. 33-42
-
-
Smallwood, S.A.1
Kelsey, G.2
-
59
-
-
1942421683
-
Gene-specific timing and epigenetic memory in oocyte imprinting
-
Lucifero, D., Mann, M. R., Bartolomei, M. S. & Trasler, J. M. Gene-specific timing and epigenetic memory in oocyte imprinting. Hum. Mol. Genet. 13, 839-849 (2004
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. 839-849
-
-
Lucifero, D.1
Mann, M.R.2
Bartolomei, M.S.3
Trasler, J.M.4
-
60
-
-
0034703865
-
The H19 methylation imprint is erased and re established differentially on the parental alleles during male germ cell development
-
Davis, T. L., Yang, G. J., McCarrey, J. R. & Bartolomei, M. S. The H19 methylation imprint is erased and re established differentially on the parental alleles during male germ cell development. Hum. Mol. Genet. 9, 2885-2894 (2000
-
(2000)
Hum. Mol. Genet
, vol.9
, pp. 2885-2894
-
-
Davis, T.L.1
Yang, G.J.2
McCarrey, J.R.3
Bartolomei, M.S.4
-
61
-
-
78649701178
-
CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19 IGF2 imprinting control region in prospermatogonia
-
Lee, D. H. et al. CTCF-dependent chromatin bias constitutes transient epigenetic memory of the mother at the H19 IGF2 imprinting control region in prospermatogonia. PLoS Genet. 6, e1001224 (2010
-
(2010)
PLoS Genet
, vol.6
, pp. 1001224
-
-
Lee, D.H.1
-
62
-
-
69449092535
-
Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals
-
Henckel, A. et al. Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals. Hum. Mol. Genet. 18, 3375-3383 (2009
-
(2009)
Hum. Mol. Genet
, vol.18
, pp. 3375-3383
-
-
Henckel, A.1
-
63
-
-
84858770341
-
TRIM28 is required for epigenetic stability during mouse oocyte to embryo transition
-
Messerschmidt, D. M. et al. TRIM28 is required for epigenetic stability during mouse oocyte to embryo transition. Science 335, 1499-1502 (2012
-
(2012)
Science
, vol.335
, pp. 1499-1502
-
-
Messerschmidt, D.M.1
-
64
-
-
53249098795
-
A maternal-zygotic effect gene, ZFP57, maintains both maternal and paternal imprints
-
Li, X. et al. A maternal-zygotic effect gene, ZFP57, maintains both maternal and paternal imprints. Dev. Cell 15, 547-557 (2008
-
(2008)
Dev. Cell
, vol.15
, pp. 547-557
-
-
Li, X.1
-
65
-
-
80555156105
-
In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions
-
Quenneville, S. et al. In embryonic stem cells, ZFP57/KAP1 recognize a methylated hexanucleotide to affect chromatin and DNA methylation of imprinting control regions. Mol. Cell 44, 361-372 (2011
-
(2011)
Mol. Cell
, vol.4
, pp. 361-372
-
-
Quenneville, S.1
-
66
-
-
33745270104
-
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases DNMT1 DNMT3A and DNMT3B
-
Tsumura, A. et al. Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases DNMT1, DNMT3A and DNMT3B. Genes Cells 11, 805-814 (2006
-
(2006)
Genes Cells
, vol.11
, pp. 805-814
-
-
Tsumura, A.1
-
67
-
-
0042132027
-
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by DNMT3A and DNMT3B
-
Chen, T., Ueda, Y., Dodge, J. E., Wang, Z. & Li, E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by DNMT3A and DNMT3B. Mol. Cell. Biol. 23, 5594-5605 (2003
-
(2003)
Mol. Cell. Biol
, vol.23
, pp. 5594-5605
-
-
Chen, T.1
Ueda, Y.2
Dodge, J.E.3
Wang, Z.4
Li, E.5
-
68
-
-
4744372577
-
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells
-
Jackson, M. et al. Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells. Mol. Cell. Biol. 24, 8862-8871 (2004
-
(2004)
Mol. Cell. Biol
, vol.24
, pp. 8862-8871
-
-
Jackson, M.1
-
69
-
-
0029935327
-
Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes
-
Tucker, K. L. et al. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes Dev. 10, 1008-1020 (1996
-
(1996)
Genes Dev
, vol.10
, pp. 1008-1020
-
-
Tucker, K.L.1
-
70
-
-
55549119925
-
Epigenetic restriction of embryonic cell lineage fate by methylation of ELF5
-
Ng, R. K. et al. Epigenetic restriction of embryonic cell lineage fate by methylation of ELF5. Nature Cell Biol. 10, 1280-1290 (2008
-
(2008)
Nature Cell Biol
, vol.10
, pp. 1280-1290
-
-
Ng, R.K.1
-
71
-
-
84857160311
-
Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo
-
Nakanishi, M. O. et al. Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo. Epigenetics 7, 173-182 (2012
-
(2012)
Epigenetics
, vol.7
, pp. 173-182
-
-
Nakanishi, M.O.1
-
72
-
-
84863889319
-
In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases
-
Arand, J. et al. In vivo control of CpG and non-CpG DNA methylation by DNA methyltransferases. PLoS Genet. 8, e1002750 (2012
-
(2012)
PLoS Genet
, vol.8
-
-
Arand, J.1
-
73
-
-
49649120959
-
Regulation of DNA methylation activity through DNMT3L promoter methylation by DNMT3 enzymes in embryonic development
-
Hu, Y. G. et al. Regulation of DNA methylation activity through DNMT3L promoter methylation by DNMT3 enzymes in embryonic development. Hum. Mol. Genet. 17, 2654-2664 (2008
-
(2008)
Hum. Mol. Genet
, vol.17
, pp. 2654-2664
-
-
Hu, Y.G.1
-
74
-
-
79956323623
-
Dynamic regulation of 5 hydroxymethylcytosine in mouse ES cells and during differentiation
-
Ficz, G. et al. Dynamic regulation of 5 hydroxymethylcytosine in mouse ES cells and during differentiation. Nature 473, 398-402 (2011
-
(2011)
Nature
, vol.473
, pp. 398-402
-
-
Ficz, G.1
-
75
-
-
84861221693
-
Quantitative sequencing of 5 methylcytosine and 5 hydroxymethylcytosine at single-base resolution
-
Booth, M. J. et al. Quantitative sequencing of 5 methylcytosine and 5 hydroxymethylcytosine at single-base resolution. Science 336, 934-937 (2012
-
(2012)
Science
, vol.336
, pp. 934-937
-
-
Booth, M.J.1
-
76
-
-
84863458292
-
Embryonic stem cell potency fluctuates with endogenous retrovirus activity
-
Macfarlan, T. S. et al. Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature 487, 57-63 (2012
-
(2012)
Nature
, vol.487
, pp. 57-63
-
-
MacFarlan, T.S.1
-
77
-
-
33645132331
-
G9A mediated irreversible epigenetic inactivation of Oct 3/4 during early embryogenesis
-
Feldman, N. et al. G9A mediated irreversible epigenetic inactivation of Oct 3/4 during early embryogenesis. Nature Cell Biol. 8, 188-194 (2006
-
(2006)
Nature Cell Biol
, vol.8
, pp. 188-194
-
-
Feldman, N.1
-
78
-
-
77956320061
-
Trgeting of de novo DNA methylation throughout the Oct 4 gene regulatory region in differentiating embryonic stem cells
-
Athanasiadou, R. et al. Targeting of de novo DNA methylation throughout the Oct 4 gene regulatory region in differentiating embryonic stem cells. PLoS ONE 5, e9937 (2010
-
(2010)
PLoS ONE
, vol.5
-
-
Athanasiadou, R.1
-
79
-
-
80052284848
-
CT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes Proc
-
You, J. S. et al. OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes. Proc. Natl Acad. Sci. USA 108, 14497-14502 (2011
-
(2011)
Natl Acad. Sci. USA
, vol.108
, pp. 14497-14502
-
-
You, J.S.1
-
80
-
-
84862662420
-
Dynamics and memory of heterochromatin in living cells
-
Hathaway, N. A. et al. Dynamics and memory of heterochromatin in living cells. Cell 149, 1447-1460 (2012
-
(2012)
Cell
, vol.149
, pp. 1447-1460
-
-
Hathaway, N.A.1
-
81
-
-
84862174297
-
Histone H1 depletion impairs embryonic stem cell differentiation
-
Zhang, Y. et al. Histone H1 depletion impairs embryonic stem cell differentiation. PLoS Genet. 8, e1002691 (2012
-
(2012)
PLoS Genet
, vol.8
, pp. 1002691
-
-
Zhang, Y.1
-
82
-
-
33749396836
-
DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
-
Maatouk, D. M. et al. DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages. Development 133, 3411-3418 (2006
-
(2006)
Development
, vol.133
, pp. 3411-3418
-
-
Maatouk, D.M.1
-
83
-
-
20144379783
-
A role for E2F6 in the restriction of male-germ-cell-specific gene expression
-
Pohlers, M. et al. A role for E2F6 in the restriction of male-germ-cell-specific gene expression. Curr. Biol. 15, 1051-1057 (2005
-
(2005)
Curr. Biol
, vol.15
, pp. 1051-1057
-
-
Pohlers, M.1
-
84
-
-
77952695371
-
NMT3B recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues
-
Velasco, G. et al. DNMT3B recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissues. Proc. Natl Acad. Sci. USA 107, 9281-9286 (2010
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 9281-9286
-
-
Velasco, G.1
-
85
-
-
78649459828
-
Targets and dynamics of promoter DNA methylation during early mouse development
-
Borgel, J. et al. Targets and dynamics of promoter DNA methylation during early mouse development. Nature Genet. 42, 1093-1100 (2010
-
(2010)
Nature Genet
, vol.42
, pp. 1093-1100
-
-
Borgel, J.1
-
86
-
-
84865843074
-
Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline
-
Hackett, J. A. et al. Promoter DNA methylation couples genome-defence mechanisms to epigenetic reprogramming in the mouse germline. Development 139, 3623-3632 (2012
-
(2012)
Development
, vol.139
, pp. 3623-3632
-
-
Hackett, J.A.1
-
87
-
-
84865693989
-
Mouse ooplasm confers context-specific reprogramming capacity
-
Chan, M. M., Smith, Z. D., Egli, D., Regev, A. & Meissner, A. Mouse ooplasm confers context-specific reprogramming capacity. Nature Genet. 44, 978-980 (2012
-
(2012)
Nature Genet
, vol.44
, pp. 978-980
-
-
Chan, M.M.1
Smith, Z.D.2
Egli, D.3
Regev, A.4
Meissner, A.5
-
88
-
-
84872770694
-
Germline DNA demethylation dynamics and imprint erasure through 5 hydroxymethylcytosine
-
6 Dec doi:10.1126/science.1229277
-
Hackett, J. A. et al. Germline DNA demethylation dynamics and imprint erasure through 5 hydroxymethylcytosine. Science 6 Dec 2012 (doi:10.1126/ science.1229277
-
(2012)
Science
-
-
Hackett, J.A.1
-
89
-
-
79956302047
-
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
-
Williams, K. et al. TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity. Nature 473, 343-348 (2011
-
(2011)
Nature
, vol.473
, pp. 343-348
-
-
Williams, K.1
-
90
-
-
79956306617
-
Regulation of X chromosome inactivation by the X inactivation centre
-
Augui, S., Nora, E. P. & Heard, E. Regulation of X chromosome inactivation by the X inactivation centre. Nature Rev. Genet. 12, 429-442 (2011
-
(2011)
Nature Rev. Genet
, vol.12
, pp. 429-442
-
-
Augui, S.1
Nora, E.P.2
Heard, E.3
-
91
-
-
84865097073
-
SMCHD1 dependent and-independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome
-
Gendrel, A. V. et al. SMCHD1 dependent and-independent pathways determine developmental dynamics of CpG island methylation on the inactive X chromosome. Dev. Cell 23, 265-279 (2012
-
(2012)
Dev. Cell
, vol.23
, pp. 265-279
-
-
Gendrel, A.V.1
-
92
-
-
80052918929
-
Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment
-
Hodges, E. et al. Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol. Cell 44, 17-28 (2011
-
(2011)
Mol. Cell
, vol.44
, pp. 17-28
-
-
Hodges, E.1
-
93
-
-
79959872458
-
Cell type-specific DNA methylation at intragenic CpG islands in the immune system
-
Deaton, A. M. et al. Cell type-specific DNA methylation at intragenic CpG islands in the immune system. Genome Res. 21, 1074-1086 (2011
-
(2011)
Genome Res
, vol.21
, pp. 1074-1086
-
-
Deaton, A.M.1
-
94
-
-
84865369147
-
DNA methylation dynamics during in vivo differentiation of blood and skin stem cells
-
Bock, C. et al. DNA methylation dynamics during in vivo differentiation of blood and skin stem cells. Mol. Cell 47, 633-647 (2012
-
(2012)
Mol. Cell
, vol.47
, pp. 633-647
-
-
Bock, C.1
-
95
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge, J. J., Snow, J. W., Kim, J. & Orkin, S. H. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 5, 442-449 (2009
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
96
-
-
70350654370
-
DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction
-
Broske, A. M. et al. DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction. Nature Genet. 41, 1207-1215 (2009
-
(2009)
Nature Genet
, vol.41
, pp. 1207-1215
-
-
Broske, A.M.1
-
97
-
-
84864612696
-
Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites
-
Hogart, A. et al. Genome-wide DNA methylation profiles in hematopoietic stem and progenitor cells reveal overrepresentation of ETS transcription factor binding sites. Genome Res. 5, 1407-1418 (2012
-
(2012)
Genome Res
, vol.5
, pp. 1407-1418
-
-
Hogart, A.1
-
98
-
-
77956902023
-
Comprehensive methylome map of lineage commitment from haematopoietic progenitors
-
Ji, H. et al. Comprehensive methylome map of lineage commitment from haematopoietic progenitors. Nature 467, 338-342 (2010
-
(2010)
Nature
, vol.467
, pp. 338-342
-
-
Ji, H.1
-
99
-
-
24344472335
-
DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling
-
Fan, G. et al. DNA methylation controls the timing of astrogliogenesis through regulation of JAK-STAT signaling. Development 132, 3345-3356 (2005
-
(2005)
Development
, vol.132
, pp. 3345-3356
-
-
Fan, G.1
-
100
-
-
34247337999
-
De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells
-
Tadokoro, Y., Ema, H., Okano, M., Li, E. & Nakauchi, H. De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells. J. Exp. Med. 204, 715-722 (2007
-
(2007)
J. Exp. Med
, vol.204
, pp. 715-722
-
-
Tadokoro, Y.1
Ema, H.2
Okano, M.3
Li, E.4
Nakauchi, H.5
-
101
-
-
84555207349
-
DNMT3A is essential for hematopoietic stem cell differentiation
-
Challen, G. A. et al. DNMT3A is essential for hematopoietic stem cell differentiation. Nature Genet. 44, 23-31 (2012
-
(2012)
Nature Genet
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
-
102
-
-
79955970344
-
Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging
-
Bocker, M. T. et al. Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging. Blood 117, e182-e189 (2011
-
(2011)
Blood 117
-
-
Bocker, M.T.1
-
103
-
-
84855292213
-
A promoter DNA demethylation landscape of human hematopoietic differentiation
-
Calvanese, V. et al. A promoter DNA demethylation landscape of human hematopoietic differentiation. Nucleic Acids Res. 40, 116-131 (2012
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 116-131
-
-
Calvanese, V.1
-
104
-
-
78650019179
-
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation
-
Figueroa, M. E. et al. Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation. Cancer Cell 18, 553-567 (2010
-
(2010)
Cancer Cell
, vol.18
, pp. 553-567
-
-
Figueroa, M.E.1
-
105
-
-
80052284526
-
Ten-eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
-
Ko, M. et al. Ten-eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice. Proc. Natl Acad. Sci. USA 108, 14566-14571 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 14566-14571
-
-
Ko, M.1
-
106
-
-
79960064353
-
TET2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio, K. et al. TET2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20, 11-24 (2011
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
-
107
-
-
79960062301
-
TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis
-
Quivoron, C. et al. TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. Cancer Cell 20, 25-38 (2011
-
(2011)
Cancer Cell
, vol.20
, pp. 25-38
-
-
Quivoron, C.1
-
108
-
-
84868103289
-
TET2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre B cells
-
Kallin, E. M. et al. TET2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre B cells. Mol. Cell 48, 266-276 (2012
-
(2012)
Mol. Cell
, vol.48
, pp. 266-276
-
-
Kallin, E.M.1
-
109
-
-
77953628087
-
Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels
-
Klug, M. et al. Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels. Genome Biol. 11, R63 (2010
-
(2010)
Genome Biol
, vol.11
-
-
Klug, M.1
-
110
-
-
18244365863
-
A critical role for DNMT1 and DNA methylation in T cell development, function, and survival
-
Lee, P. P. et al. A critical role for DNMT1 and DNA methylation in T cell development, function, and survival. Immunity 15, 763-774 (2001
-
(2001)
Immunity
, vol.15
, pp. 763-774
-
-
Lee, P.P.1
-
111
-
-
33645770934
-
DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion
-
Chappell, C., Beard, C., Altman, J., Jaenisch, R. & Jacob, J. DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion. J. Immunol. 176, 4562-4572 (2006
-
(2006)
J. Immunol
, vol.176
, pp. 4562-4572
-
-
Chappell, C.1
Beard, C.2
Altman, J.3
Jaenisch, R.4
Jacob, J.5
-
112
-
-
80053376487
-
DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B cell differentiation
-
Shaknovich, R. et al. DNA methyltransferase 1 and DNA methylation patterning contribute to germinal center B cell differentiation. Blood 118, 3559-3569 (2011
-
(2011)
Blood
, vol.118
, pp. 3559-3569
-
-
Shaknovich, R.1
-
113
-
-
81055139701
-
Global DNA demethylation during mouse erythropoiesis in vivo
-
Shearstone, J. R. et al. Global DNA demethylation during mouse erythropoiesis in vivo. Science 334, 799-802 (2011
-
(2011)
Science
, vol.334
, pp. 799-802
-
-
Shearstone, J.R.1
-
114
-
-
4644231710
-
DNA methylation is a nonredundant repressor of the Th2 effector program
-
Makar, K. W. & Wilson, C. B. DNA methylation is a nonredundant repressor of the Th2 effector program. J. Immunol. 173, 4402-4406 (2004
-
(2004)
J. Immunol
, vol.173
, pp. 4402-4406
-
-
Makar, K.W.1
Wilson, C.B.2
-
115
-
-
0346752253
-
Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells
-
Makar, K. W. et al. Active recruitment of DNA methyltransferases regulates interleukin 4 in thymocytes and T cells. Nature Immunol. 4, 1183-1190 (2003
-
(2003)
Nature Immunol
, vol.4
, pp. 1183-1190
-
-
Makar, K.W.1
-
116
-
-
0037340215
-
Selective stable demethylation of the interleukin 2 gene enhances transcription by an active process
-
Bruniquel, D. & Schwartz, R. H. Selective, stable demethylation of the interleukin 2 gene enhances transcription by an active process. Nature Immunol. 4, 235-240 (2003
-
(2003)
Nature Immunol
, vol.4
, pp. 235-240
-
-
Bruniquel, D.1
Schwartz, R.H.2
-
117
-
-
33644854871
-
A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory
-
Murayama, A. et al. A specific CpG site demethylation in the human interleukin 2 gene promoter is an epigenetic memory. EMBO J. 25, 1081-1092 (2006
-
(2006)
EMBO J.
, vol.25
, pp. 1081-1092
-
-
Murayama, A.1
-
118
-
-
76749133610
-
Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T cell fate
-
Zheng, Y. et al. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T cell fate. Nature 463, 808-812 (2010
-
(2010)
Nature
, vol.463
, pp. 808-812
-
-
Zheng, Y.1
-
119
-
-
7544231794
-
Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells
-
Lorincz, M. C., Dickerson, D. R., Schmitt, M. & Groudine, M. Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells. Nature Struct. Mol. Biol. 11, 1068-1075 (2004
-
(2004)
Nature Struct. Mol. Biol
, vol.11
, pp. 1068-1075
-
-
Lorincz, M.C.1
Dickerson, D.R.2
Schmitt, M.3
Groudine, M.4
-
120
-
-
77649267695
-
Dynamic changes in the human methylome during differentiation
-
Laurent, L. et al. Dynamic changes in the human methylome during differentiation. Genome Res. 20, 320-331 (2010
-
(2010)
Genome Res
, vol.20
, pp. 320-331
-
-
Laurent, L.1
-
121
-
-
80455176999
-
CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing
-
Shukla, S. et al. CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing. Nature 479, 74-79 (2011
-
(2011)
Nature
, vol.479
, pp. 74-79
-
-
Shukla, S.1
-
122
-
-
22444448587
-
BLIMP1 is a critical determinant of the germ cell lineage in mice
-
Ohinata, Y. et al. BLIMP1 is a critical determinant of the germ cell lineage in mice. Nature 436, 207-213 (2005
-
(2005)
Nature
, vol.436
, pp. 207-213
-
-
Ohinata, Y.1
-
123
-
-
33744795753
-
BLIMP1 associates with PRMT5 and directs histone arginine methylation in mouse germ cells
-
Ancelin, K. et al. BLIMP1 associates with PRMT5 and directs histone arginine methylation in mouse germ cells. Nature Cell Biol. 8, 623-630 (2006
-
(2006)
Nature Cell Biol
, vol.8
, pp. 623-630
-
-
Ancelin, K.1
-
124
-
-
68949141428
-
Germ cell specification in mice
-
Saitou, M. Germ cell specification in mice. Curr. Opin. Genet. Dev. 19, 386-395 (2009
-
(2009)
Curr. Opin. Genet. Dev
, vol.19
, pp. 386-395
-
-
Saitou, M.1
-
125
-
-
43049095234
-
Requirement of OCT3/4 function for germ cell specification
-
Okamura, D., Tokitake, Y., Niwa, H. & Matsui, Y. Requirement of OCT3/4 function for germ cell specification. Dev. Biol. 317, 576-584 (2008
-
(2008)
Dev. Biol
, vol.317
, pp. 576-584
-
-
Okamura, D.1
Tokitake, Y.2
Niwa, H.3
Matsui, Y.4
-
126
-
-
0037130207
-
A molecular programme for the specification of germ cell fate in mice
-
Saitou, M., Barton, S. C. & Surani, M. A. A molecular programme for the specification of germ cell fate in mice. Nature 418, 293-300 (2002
-
(2002)
Nature
, vol.418
, pp. 293-300
-
-
Saitou, M.1
Barton, S.C.2
Surani, M.A.3
-
127
-
-
18344367065
-
Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells
-
Sato, M. et al. Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells. Mech. Dev. 113, 91-94 (2002
-
(2002)
Mech. Dev
, vol.113
, pp. 91-94
-
-
Sato, M.1
-
128
-
-
12944308793
-
Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice
-
Seki, Y. et al. Extensive and orderly reprogramming of genome-wide chromatin modifications associated with specification and early development of germ cells in mice. Dev. Biol. 278, 440-458 (2005
-
(2005)
Dev. Biol
, vol.278
, pp. 440-458
-
-
Seki, Y.1
-
129
-
-
0036768615
-
Epigenetic reprogramming in mouse primordial germ cells
-
Hajkova, P. et al. Epigenetic reprogramming in mouse primordial germ cells. Mech. Dev. 117, 15-23 (2002
-
(2002)
Mech. Dev
, vol.117
, pp. 15-23
-
-
Hajkova, P.1
-
130
-
-
0037710466
-
Methylation dynamics of repetitive DNA elements in the mouse germ cell lineage
-
Lees-Murdock, D. J., De Felici, M. & Walsh, C. P. Methylation dynamics of repetitive DNA elements in the mouse germ cell lineage. Genomics 82, 230-237 (2003
-
(2003)
Genomics
, vol.82
, pp. 230-237
-
-
Lees-Murdock, D.J.1
De Felici, M.2
Walsh, C.P.3
-
131
-
-
0037298161
-
Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse
-
Lane, N. et al. Resistance of IAPs to methylation reprogramming may provide a mechanism for epigenetic inheritance in the mouse. Genesis 35, 88-93 (2003
-
(2003)
Genesis
, vol.35
, pp. 88-93
-
-
Lane, N.1
-
132
-
-
77249148019
-
Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency
-
Popp, C. et al. Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency. Nature 463, 1101-1105 (2010
-
(2010)
Nature
, vol.463
, pp. 1101-1105
-
-
Popp, C.1
-
133
-
-
84859519339
-
Global profiling of DNA methylation erasure in mouse primordial germ cells
-
Guibert, S., Forne, T. & Weber, M. Global profiling of DNA methylation erasure in mouse primordial germ cells. Genome Res. 22, 633-641 (2012
-
(2012)
Genome Res
, vol.22
, pp. 633-641
-
-
Guibert, S.1
Forne, T.2
Weber, M.3
-
134
-
-
84871702441
-
The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
-
Seisenberger, S. et al. The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol. Cell 48, 849-862 (2012
-
(2012)
Mol. Cell
, vol.48
, pp. 849-862
-
-
Seisenberger, S.1
-
135
-
-
45349086923
-
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
-
Farthing, C. R. et al. Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet. 4, e1000116 (2008
-
(2008)
PLoS Genet
, vol.4
-
-
Farthing, C.R.1
-
136
-
-
49649125042
-
Genome-scale DNA methylation maps of pluripotent and differentiated cells
-
Meissner, A. et al. Genome-scale DNA methylation maps of pluripotent and differentiated cells. Nature 454, 766-770 (2008
-
(2008)
Nature
, vol.454
, pp. 766-770
-
-
Meissner, A.1
-
137
-
-
77954345408
-
Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway
-
Hajkova, P. et al. Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway. Science 329, 78-82 (2010
-
(2010)
Science
, vol.329
, pp. 78-82
-
-
Hajkova, P.1
-
138
-
-
79961139741
-
Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development
-
Dawlaty, M. M. et al. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell 9, 166-175 (2011
-
(2011)
Cell Stem Cell
, vol.9
, pp. 166-175
-
-
Dawlaty, M.M.1
-
139
-
-
84871438065
-
Tet1 controls meiosis by regulating meiotic gene expression
-
doi:10.1038/nature117091 20 1 Dec 2012
-
Yamaguchi, S. et al. Tet1 controls meiosis by regulating meiotic gene expression. Nature 20 Dec 2012 (doi:10.1038/nature11709
-
Nature
-
-
Yamaguchi, S.1
-
140
-
-
45349107280
-
Complex genome-wide transcription dynamics orchestrated by BLIMP1 for the specification of the germ cell lineage in mice
-
Kurimoto, K. et al. Complex genome-wide transcription dynamics orchestrated by BLIMP1 for the specification of the germ cell lineage in mice. Genes Dev. 22, 1617-1635 (2008
-
(2008)
Genes Dev
, vol.22
, pp. 1617-1635
-
-
Kurimoto, K.1
-
141
-
-
84873570094
-
Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice
-
Dec doi:10.1038/ emboj.2012.331
-
Kagiwada, S., Kurimoto, K., Hirota, T., Yamaji, M. & Saitou, M. Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice. EMBO J. 14 Dec 2012 (doi:10.1038/ emboj.2012.331
-
(2012)
EMBO J
, vol.14
-
-
Kagiwada, S.1
Kurimoto, K.2
Hirota, T.3
Yamaji, M.4
Saitou, M.5
-
142
-
-
34447522791
-
Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice
-
Seki, Y. et al. Cellular dynamics associated with the genome-wide epigenetic reprogramming in migrating primordial germ cells in mice. Development 134, 2627-2638 (2007
-
(2007)
Development
, vol.134
, pp. 2627-2638
-
-
Seki, Y.1
-
143
-
-
42249094716
-
Chromatin dynamics during epigenetic reprogramming in the mouse germ line
-
Hajkova, P. et al. Chromatin dynamics during epigenetic reprogramming in the mouse germ line. Nature 452, 877-881 (2008
-
(2008)
Nature
, vol.452
, pp. 877-881
-
-
Hajkova, P.1
-
144
-
-
79960926264
-
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
-
Smallwood, S. A. et al. Dynamic CpG island methylation landscape in oocytes and preimplantation embryos. Nature Genet. 43, 811-814 (2011
-
(2011)
Nature Genet
, vol.43
, pp. 811-814
-
-
Smallwood, S.A.1
-
145
-
-
34347213437
-
Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells
-
Oakes, C. C., La Salle, S., Smiraglia, D. J., Robaire, B. & Trasler, J. M. Developmental acquisition of genome-wide DNA methylation occurs prior to meiosis in male germ cells. Dev. Biol. 307, 368-379 (2007
-
(2007)
Dev. Biol
, vol.307
, pp. 368-379
-
-
Oakes, C.C.1
La Salle, S.2
Smiraglia, D.J.3
Robaire, B.4
Trasler, J.M.5
-
146
-
-
0035930660
-
DNMT3L and the establishment of maternal genomic imprints
-
Bourc'his, D., Xu, G. L., Lin, C. S., Bollman, B. & Bestor, T. H. DNMT3L and the establishment of maternal genomic imprints. Science 294, 2536-2539 (2001
-
(2001)
Science
, vol.294
, pp. 2536-2539
-
-
Bourc'His, D.1
Xu, G.L.2
Lin, C.S.3
Bollman, B.4
Bestor, T.H.5
-
147
-
-
0036333103
-
DNMT3L cooperates with the DNMT3 family of de novo DNA methyltransferases to establish maternal imprints in mice
-
Hata, K., Okano, M., Lei, H. & Li, E. DNMT3L cooperates with the DNMT3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 129, 1983-1993 (2002
-
(2002)
Development
, vol.129
, pp. 1983-1993
-
-
Hata, K.1
Okano, M.2
Lei, H.3
Li, E.4
-
148
-
-
3042584653
-
Essential role for de novo DNA methyltransferase DNMT3A in paternal and maternal imprinting
-
Kaneda, M. et al. Essential role for de novo DNA methyltransferase DNMT3A in paternal and maternal imprinting. Nature 429, 900-903 (2004
-
(2004)
Nature
, vol.429
, pp. 900-903
-
-
Kaneda, M.1
-
149
-
-
77950641592
-
Genetic evidence for DNMT3A dependent imprinting during oocyte growth obtained by conditional knockout with Zp3 Cre and complete exclusion of DNMT3B by chimera formation
-
Feb (doi:10.1111/j.1365 2443. 2009.01374
-
Kaneda, M. et al. Genetic evidence for DNMT3A dependent imprinting during oocyte growth obtained by conditional knockout with Zp3 Cre and complete exclusion of DNMT3B by chimera formation. Genes Cells 1 Feb 2012 (doi:10.1111/j.1365 2443.2009.01374.x
-
(2012)
Genes Cells
, vol.1
-
-
Kaneda, M.1
-
150
-
-
4544223707
-
Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking DNMT3L
-
Bourc'his, D. & Bestor, T. H. Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking DNMT3L. Nature 431, 96-99 (2004
-
(2004)
Nature
, vol.431
, pp. 96-99
-
-
Bourc'His, D.1
Bestor, T.H.2
-
151
-
-
34548705374
-
Role of the DNMT3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse
-
Kato, Y. et al. Role of the DNMT3 family in de novo methylation of imprinted and repetitive sequences during male germ cell development in the mouse. Hum. Mol. Genet. 16, 2272-2280 (2007
-
(2007)
Hum. Mol. Genet
, vol.16
, pp. 2272-2280
-
-
Kato, Y.1
-
152
-
-
84857467013
-
Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks
-
Kobayashi, H. et al. Contribution of intragenic DNA methylation in mouse gametic DNA methylomes to establish oocyte-specific heritable marks. PLoS Genet. 8, e1002440 (2012
-
(2012)
PLoS Genet
, vol.8
-
-
Kobayashi, H.1
-
153
-
-
33751523649
-
LSH is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells
-
De La Fuente, R. et al. LSH is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells. Nature Cell Biol. 8, 1448-1454 (2006
-
(2006)
Nature Cell Biol
, vol.8
, pp. 1448-1454
-
-
De La Fuente, R.1
-
154
-
-
0025800593
-
Methylation levels of maternal and paternal genomes during preimplantation development
-
Howlett, S. K. & Reik, W. Methylation levels of maternal and paternal genomes during preimplantation development. Development 113, 119-127 (1991
-
(1991)
Development
, vol.113
, pp. 119-127
-
-
Howlett, S.K.1
Reik, W.2
-
155
-
-
52049098967
-
A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice
-
Aravin, A. A. et al. A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice. Mol. Cell 31, 785-799 (2008
-
(2008)
Mol. Cell
, vol.31
, pp. 785-799
-
-
Aravin, A.A.1
-
156
-
-
79956052873
-
Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus
-
Watanabe, T. et al. Role for piRNAs and noncoding RNA in de novo DNA methylation of the imprinted mouse Rasgrf1 locus. Science 332, 848-852 (2011
-
(2011)
Science
, vol.332
, pp. 848-852
-
-
Watanabe, T.1
-
157
-
-
34248160438
-
Developmentally regulated piRNA clusters implicate MILI in transposon control
-
Aravin, A. A., Sachidanandam, R., Girard, A., Fejes-Toth, K. & Hannon, G. J. Developmentally regulated piRNA clusters implicate MILI in transposon control. Science 316, 744-747 (2007
-
(2007)
Science
, vol.316
, pp. 744-747
-
-
Aravin, A.A.1
Sachidanandam, R.2
Girard, A.3
Fejes-Toth, K.4
Hannon, G.J.5
-
158
-
-
41649116098
-
DNA methylation of retrotransposon genes is regulated by PIWI family members MILI and MIWI2 in murine fetal testes
-
Kuramochi-Miyagawa, S. et al. DNA methylation of retrotransposon genes is regulated by PIWI family members MILI and MIWI2 in murine fetal testes. Genes Dev. 22, 908-917 (2008
-
(2008)
Genes Dev
, vol.22
, pp. 908-917
-
-
Kuramochi-Miyagawa, S.1
-
159
-
-
0036145567
-
Dynamic reprogramming of DNA methylation in the early mouse embryo
-
Santos, F., Hendrich, B., Reik, W. & Dean, W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol. 241, 172-182 (2002
-
(2002)
Dev. Biol
, vol.241
, pp. 172-182
-
-
Santos, F.1
Hendrich, B.2
Reik, W.3
Dean, W.4
-
160
-
-
0034176639
-
Active demethylation of the paternal genome in the mouse zygote
-
Oswald, J. et al. Active demethylation of the paternal genome in the mouse zygote. Curr. Biol. 10, 475-478 (2000
-
(2000)
Curr. Biol
, vol.10
, pp. 475-478
-
-
Oswald, J.1
-
161
-
-
4744348332
-
Differential DNA methylation reprogramming of various repetitive sequences in mouse preimplantation embryos
-
Kim, S. H. et al. Differential DNA methylation reprogramming of various repetitive sequences in mouse preimplantation embryos. Biochem. Biophys. Res. Commun. 324, 58-63 (2004
-
(2004)
Biochem. Biophys. Res. Commun
, vol.324
, pp. 58-63
-
-
Kim, S.H.1
-
162
-
-
77953596050
-
Dmic link of dna demethylation dna strand breaks and repair in mouse zygotes
-
Wossidlo, M. et al. Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes. EMBO J. 29, 1877-1888 (2010
-
(2010)
EMBO J.
, vol.29
, pp. 1877-1888
-
-
Wossidlo, M.1
-
163
-
-
79952763586
-
Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5 methylcytosine
-
Iqbal, K., Jin, S. G., Pfeifer, G. P. & Szabo, P. E. Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5 methylcytosine. Proc. Natl Acad. Sci. USA 108, 3642-3647 (2011
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 3642-3647
-
-
Iqbal, K.1
Jin, S.G.2
Pfeifer, G.P.3
Szabo, P.E.4
-
164
-
-
79952713567
-
5 Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming
-
Wossidlo, M. et al. 5 hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming. Nature Commun. 2, 241 (2011
-
(2011)
Nature Commun
, vol.2
, pp. 241
-
-
Wossidlo, M.1
-
165
-
-
80053348585
-
The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes
-
Gu, T. P. et al. The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes. Nature 477, 606-610 (2011
-
(2011)
Nature
, vol.477
, pp. 606-610
-
-
Gu, T.P.1
-
166
-
-
75749142980
-
A role for the elongator complex in zygotic paternal genome demethylation
-
Okada, Y., Yamagata, K., Hong, K., Wakayama, T. & Zhang, Y. A role for the elongator complex in zygotic paternal genome demethylation. Nature 463, 554-558 (2010
-
(2010)
Nature
, vol.463
, pp. 554-558
-
-
Okada, Y.1
Yamagata, K.2
Hong, K.3
Wakayama, T.4
Zhang, Y.5
-
167
-
-
80054097425
-
Replication-dependent loss of 5 hydroxymethylcytosine in mouse preimplantation embryos
-
Inoue, A. & Zhang, Y. Replication-dependent loss of 5 hydroxymethylcytosine in mouse preimplantation embryos. Science 334, 194 (2011
-
(2011)
Science
, vol.334
, pp. 194
-
-
Inoue, A.1
Zhang, Y.2
-
168
-
-
70350002304
-
Distribution of p53 binding protein 1 (53BP1) and phosphorylated H2A.X during mouse preimplantation development in the absence of DNA damage
-
Ziegler-Birling, C., Helmrich, A., Tora, L. & Torres-Padilla, M. E. Distribution of p53 binding protein 1 (53BP1) and phosphorylated H2A.X during mouse preimplantation development in the absence of DNA damage. Int. J. Dev. Biol. 53, 1003-1011 (2009
-
(2009)
Int. J. Dev. Biol
, vol.53
, pp. 1003-1011
-
-
Ziegler-Birling, C.1
Helmrich, A.2
Tora, L.3
Torres-Padilla, M.E.4
-
169
-
-
79955029493
-
Epigenetic reprogramming and development: B unique heterochromatin organization in the preimplantation mouse embryo
-
Burton, A. & Torres-Padilla, M. E. Epigenetic reprogramming and development: B unique heterochromatin organization in the preimplantation mouse embryo. Brief Funct. Genom. 9, 444-454 (2010
-
(2010)
Brief Funct. Genom
, vol.9
, pp. 444-454
-
-
Burton, A.1
Torres-Padilla, M.E.2
-
170
-
-
40849129243
-
PRC1 and SUV39H specify parental asymmetry at constitutive heterochromatin in early mouse embryos
-
Puschendorf, M. et al. PRC1 and SUV39H specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nature Genet. 40, 411-420 (2008
-
(2008)
Nature Genet
, vol.40
, pp. 411-420
-
-
Puschendorf, M.1
-
171
-
-
14844286976
-
Dynamic chromatin modifications characterise the first cell cycle in mouse embryos
-
Santos, F., Peters, A. H., Otte, A. P., Reik, W. & Dean, W. Dynamic chromatin modifications characterise the first cell cycle in mouse embryos. Dev. Biol. 280, 225-236 (2005
-
(2005)
Dev. Biol
, vol.280
, pp. 225-236
-
-
Santos, F.1
Peters, A.H.2
Otte, A.P.3
Reik, W.4
Dean, W.5
-
172
-
-
84862551364
-
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos
-
Nakamura, T. et al. PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos. Nature 486, 415-419 (2012
-
(2012)
Nature
, vol.486
, pp. 415-419
-
-
Nakamura, T.1
-
173
-
-
33845885282
-
PGC7/Stella protects against DNA demethylation in early embryogenesis
-
Nakamura, T. et al. PGC7/Stella protects against DNA demethylation in early embryogenesis. Nature Cell Biol. 9, 64-71 (2007
-
(2007)
Nature Cell Biol
, vol.9
, pp. 64-71
-
-
Nakamura, T.1
-
174
-
-
45349108598
-
Maternal and zygotic DNMT1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development
-
Hirasawa, R. et al. Maternal and zygotic DNMT1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes Dev. 22, 1607-1616 (2008
-
(2008)
Genes Dev
, vol.22
, pp. 1607-1616
-
-
Hirasawa, R.1
-
175
-
-
0037093255
-
Dynamics of DNMT1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development
-
Ratnam, S. et al. Dynamics of DNMT1 methyltransferase expression and intracellular localization during oogenesis and preimplantation development. Dev. Biol. 245, 304-314 (2002
-
(2002)
Dev. Biol
, vol.245
, pp. 304-314
-
-
Ratnam, S.1
-
176
-
-
84860221291
-
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
-
Hashimoto, H. et al. Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation. Nucleic Acids Res. 40, 4841-4849 (2012
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 4841-4849
-
-
Hashimoto, H.1
-
177
-
-
79959431845
-
Recognition of 5 hydroxymethylcytosine by the UHRF1 SRA domain
-
Frauer, C. et al. Recognition of 5 hydroxymethylcytosine by the UHRF1 SRA domain. PLoS ONE 6, e21306 (2011
-
(2011)
PLoS ONE
, vol.6
-
-
Frauer, C.1
-
178
-
-
33847055935
-
Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1
-
Valinluck, V. & Sowers, L. C. Endogenous cytosine damage products alter the site selectivity of human DNA maintenance methyltransferase DNMT1. Cancer Res. 67, 946-950 (2007
-
(2007)
Cancer Res
, vol.67
, pp. 946-950
-
-
Valinluck, V.1
Sowers, L.C.2
-
179
-
-
34548458560
-
Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3
-
Reese, K. J., Lin, S., Verona, R. I., Schultz, R. M. & Bartolomei, M. S. Maintenance of paternal methylation and repression of the imprinted H19 gene requires MBD3. PLoS Genet. 3, e137 (2007
-
(2007)
PLoS Genet
, vol.3
-
-
Reese, K.J.1
Lin, S.2
Verona, R.I.3
Schultz, R.M.4
Bartolomei, M.S.5
-
180
-
-
84455167621
-
MDB3/NURD complex regulates expression of 5 hydroxymethylcytosine marked genes in embryonic stem cells
-
Yildirim, O. et al. MDB3/NURD complex regulates expression of 5 hydroxymethylcytosine marked genes in embryonic stem cells. Cell 147, 1498-1510 (2011
-
(2011)
Cell
, vol.147
, pp. 1498-1510
-
-
Yildirim, O.1
-
181
-
-
77956189495
-
Role of TET proteins in 5mC to 5hmC conversion ES cell self-renewal and inner cell mass specification
-
Ito, S. et al. Role of TET proteins in 5mC to 5hmC conversion, ES cell self-renewal and inner cell mass specification. Nature 466, 1129-1133 (2010
-
(2010)
Nature
, vol.466
, pp. 1129-1133
-
-
Ito, S.1
-
182
-
-
0035868824
-
Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development
-
Hendrich, B., Guy, J., Ramsahoye, B., Wilson, V. A. & Bird, A. Closely related proteins MBD2 and MBD3 play distinctive but interacting roles in mouse development. Genes Dev. 15, 710-723 (2001
-
(2001)
Genes Dev
, vol.15
, pp. 710-723
-
-
Hendrich, B.1
Guy, J.2
Ramsahoye, B.3
Wilson, V.A.4
Bird, A.5
-
183
-
-
34247333474
-
MBD3 a component of the NuRD co repressor complex, is required for development of pluripotent cells
-
Kaji, K., Nichols, J. & Hendrich, B. MBD3, a component of the NuRD co repressor complex, is required for development of pluripotent cells. Development 134, 1123-1132 (2007
-
(2007)
Development
, vol.134
, pp. 1123-1132
-
-
Kaji, K.1
Nichols, J.2
Hendrich, B.3
-
184
-
-
0142243222
-
Control elements of Dnmt1 gene are regulated in cell-cycle dependent manner
-
Kishikawa, S., Murata, T., Ugai, H., Yamazaki, T. & Yokoyama, K. K. Control elements of Dnmt1 gene are regulated in cell-cycle dependent manner. Nucleic Acids Res. (SUPPL3), 307-308 (2003
-
(2003)
Nucleic Acids Res.
, Issue.SUPPL. 3
, pp. 307-308
-
-
Kishikawa, S.1
Murata, T.2
Ugai, H.3
Yamazaki, T.4
Yokoyama, K.K.5
-
185
-
-
0030770835
-
Human DNA-(cytosine 5) methyltransferase-PCNA complex as a target for p21WAF1
-
Chuang, L. S. et al. Human DNA-(cytosine 5) methyltransferase-PCNA complex as a target for p21WAF1. Science 277, 1996-2000 (1997
-
(1997)
Science
, vol.277
, pp. 1996-2000
-
-
Chuang, L.S.1
-
186
-
-
36849072573
-
The SRA protein Np95 mediates epigenetic inheritance by recruiting DNMT1 to methylated DNA
-
Sharif, J. et al. The SRA protein Np95 mediates epigenetic inheritance by recruiting DNMT1 to methylated DNA. Nature 450, 908-912 (2007
-
(2007)
Nature
, vol.450
, pp. 908-912
-
-
Sharif, J.1
-
187
-
-
34648833002
-
UHRF1 plays a role in maintaining DNA methylation in mammalian cells
-
Bostick, M. et al. UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760-1764 (2007
-
(2007)
Science
, vol.317
, pp. 1760-1764
-
-
Bostick, M.1
-
188
-
-
53649097070
-
Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism
-
Arita, K., Ariyoshi, M., Tochio, H., Nakamura, Y. & Shirakawa, M. Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism. Nature 455, 818-821 (2008
-
(2008)
Nature
, vol.455
, pp. 818-821
-
-
Arita, K.1
Ariyoshi, M.2
Tochio, H.3
Nakamura, Y.4
Shirakawa, M.5
-
189
-
-
53649088595
-
Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1
-
Avvakumov, G. V. et al. Structural basis for recognition of hemi-methylated DNA by the SRA domain of human UHRF1. Nature 455, 822-825 (2008
-
(2008)
Nature
, vol.455
, pp. 822-825
-
-
Avvakumov, G.V.1
-
190
-
-
78049510229
-
DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination
-
ra80
-
Du, Z. et al. DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. Sci. Signal. 3, ra80 (2010
-
(2010)
Sci. Signal
, vol.3
-
-
Du, Z.1
-
191
-
-
65249102251
-
Regulation of DNMT1 stability through SET7 mediated lysine methylation in mammalian cells
-
Esteve, P. O. et al. Regulation of DNMT1 stability through SET7 mediated lysine methylation in mammalian cells. Proc. Natl Acad. Sci. USA 106, 5076-5081 (2009
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 5076-5081
-
-
Esteve, P.O.1
-
192
-
-
0033919595
-
Dnmt1 forms a complex with rb e2f1 and hdac1 and represses transcription from e2f responsive promoters
-
Robertson, K. D. et al. DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F responsive promoters. Nature Genet. 25, 338-342 (2000
-
(2000)
Nature Genet
, vol.25
, pp. 338-342
-
-
Robertson, K.D.1
-
193
-
-
58149156264
-
The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation
-
Wang, J. et al. The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nature Genet. 41, 125-129 (2009
-
(2009)
Nature Genet
, vol.41
, pp. 125-129
-
-
Wang, J.1
-
194
-
-
0033988813
-
DNA methyltransferase DNMT1 associates with histone deacetylase activity
-
Fuks, F., Burgers, W. A., Brehm, A., Hughes-Davies, L. & Kouzarides, T. DNA methyltransferase DNMT1 associates with histone deacetylase activity. Nature Genet. 24, 88-91 (2000
-
(2000)
Nature Genet
, vol.24
, pp. 88-91
-
-
Fuks, F.1
Burgers, W.A.2
Brehm, A.3
Hughes-Davies, L.4
Kouzarides, T.5
-
195
-
-
84869087517
-
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation
-
Rothbart, S. B. et al. Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation. Nature Struct. Mol. Biol. 19, 1155-1160 (2012
-
(2012)
Nature Struct. Mol. Biol
, vol.19
, pp. 1155-1160
-
-
Rothbart, S.B.1
-
196
-
-
0036837862
-
DNA methylation density influences the stability of an epigenetic imprint and DNMT3A/B independent de novo methylation
-
Lorincz, M. C., Schubeler, D., Hutchinson, S. R., Dickerson, D. R. & Groudine, M. DNA methylation density influences the stability of an epigenetic imprint and DNMT3A/B independent de novo methylation. Mol. Cell. Biol. 22, 7572-7580 (2002
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 7572-7580
-
-
Lorincz, M.C.1
Schubeler, D.2
Hutchinson, S.R.3
Dickerson, D.R.4
Groudine, M.5
-
197
-
-
66149146320
-
Conversion of 5 methylcytosine to 5 hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M. et al. Conversion of 5 methylcytosine to 5 hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935 (2009
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
-
198
-
-
79956292024
-
Dual functions of TET1 in transcriptional regulation in mouse embryonic stem cells
-
Wu, H. et al. Dual functions of TET1 in transcriptional regulation in mouse embryonic stem cells. Nature 473, 389-393 (2011
-
(2011)
Nature
, vol.473
, pp. 389-393
-
-
Wu, H.1
-
199
-
-
79959937861
-
Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair
-
Cortellino, S. et al. Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair. Cell 146, 67-79 (2011
-
(2011)
Cell
, vol.146
, pp. 67-79
-
-
Cortellino, S.1
-
200
-
-
79951810964
-
Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability
-
Cortazar, D. et al. Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability. Nature 470, 419-423 (2011
-
(2011)
Nature
, vol.470
, pp. 419-423
-
-
Cortazar, D.1
-
201
-
-
79953089167
-
PIWI-interacting small RNAs: The vanguard of genome defence
-
Siomi, M. C., Sato, K., Pezic, D. & Aravin, A. A. PIWI-interacting small RNAs: The vanguard of genome defence. Nature Rev. Mol. Cell Biol. 12, 246-258 (2011
-
(2011)
Nature Rev. Mol. Cell Biol
, vol.12
, pp. 246-258
-
-
Siomi, M.C.1
Sato, K.2
Pezic, D.3
Aravin, A.A.4
-
202
-
-
77955409741
-
MOV10L1 is necessary for protection of spermatocytes against retrotransposons by PIWI-interacting RNAs
-
Frost, R. J. et al. MOV10L1 is necessary for protection of spermatocytes against retrotransposons by PIWI-interacting RNAs. Proc. Natl Acad. Sci. USA 107, 11847-11852 (2010
-
(2010)
Proc. Natl Acad. Sci. USA
, vol.107
, pp. 11847-11852
-
-
Frost, R.J.1
-
203
-
-
67349141725
-
Loss of the MILI-interacting Tudor domain-containing protein 1 activates transposons and alters the MILI-Associated small RNA profile
-
Reuter, M. et al. Loss of the MILI-interacting Tudor domain-containing protein 1 activates transposons and alters the MILI-Associated small RNA profile. Nature Struct. Mol. Biol. 16, 639-646 (2009
-
(2009)
Nature Struct. Mol. Biol
, vol.16
, pp. 639-646
-
-
Reuter, M.1
-
204
-
-
71649101009
-
The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline
-
Shoji, M. et al. The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev. Cell 17, 775-787 (2009
-
(2009)
Dev. Cell
, vol.17
, pp. 775-787
-
-
Shoji, M.1
|