PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos

Nature

Volumn 486, Issue 7403, 2012, Pages 415-419

  Nakamura, Toshinobu ^a,d   Liu, Yu Jung ^a   Nakashima, Hiroyuki ^a   Umehara, Hiroki ^a   Inoue, Kimiko ^b   Matoba, Shogo ^b   Tachibana, Makoto ^c   Ogura, Atsuo ^b   Shinkai, Yoichi ^c   Nakano, Toru ^a  

^a OSAKA UNIVERSITY   (Japan)

^b RIKEN BIORESOURCE CENTER   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYMETHYLCYTOSINE; 5 METHYLCYTOSINE; CELL PROTEIN; HISTONE H3; LYSINE; PROTEIN PGC7; UNCLASSIFIED DRUG;

CHEMICAL BINDING; EMBRYO; ENZYME ACTIVITY; GENOME; SPERM;

ANIMAL TISSUE; ARTICLE; CHROMATIN; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; EMBRYO DEVELOPMENT; EMBRYONIC STEM CELL; EPIGENETICS; GENE CONVERSION; GENE EXPRESSION REGULATION; MOUSE; NONHUMAN; PRIMORDIAL GERM CELL; PRIORITY JOURNAL; PROTEIN BINDING; SOMATIC CELL;

5-METHYLCYTOSINE; ANIMALS; CHROMATIN; CYTOSINE; DNA METHYLATION; DNA-BINDING PROTEINS; EMBRYO, MAMMALIAN; EMBRYONIC DEVELOPMENT; FEMALE; GENOMIC IMPRINTING; HISTONES; LYSINE; MALE; METHYLATION; MICE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; RAS-GRF1; REPRESSOR PROTEINS; RNA, UNTRANSLATED; SPERMATOZOA;

EID: 84862551364     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11093     Document Type: Article

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