Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX

Nature

Volumn 497, Issue 7447, 2013, Pages 122-126

  Ko, Myunggon ^a   An, Jungeun ^a   Bandukwala, Hozefa S ^a   Chavez, Lukas ^a   Äijö, Tarmo ^a,b   Pastor, William A ^a,f   Segal, Matthew F ^a   Li, Huiming ^c,g   Koh, Kian Peng ^c,h   Lähdesmäki, Harri ^b   Hogan, Patrick G ^a   Aravind, L ^d   Rao, Anjana ^a,c,e  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b AALTO UNIVERSITY   (Finland)

^c BOSTON CHILDREN S HOSPITAL   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e SANFORD CONSORTIUM FOR REGENERATIVE MEDICINE   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g Bristol Myers Squibb   (United States)

^h UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCYTOSINE; DIOXYGENASE; GENOMIC DNA; IDAX PROTEIN; PROTEIN INHIBITOR; TET2 PROTEIN; UNCLASSIFIED DRUG;

BIODEGRADATION; DNA; ENZYME ACTIVITY; GENE EXPRESSION; METHYLATION; ORGANIC COMPOUND; OXIDATION; PROTEIN; RECRUITMENT (POPULATION DYNAMICS); TRANSLOCATION;

ARTICLE; CELL STRAIN HEK293; CPG ISLAND; DNA BINDING; DNA SEQUENCE; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; KIDNEY CARCINOMA; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; VILLOUS ADENOMA;

5-METHYLCYTOSINE; ANIMALS; BASE SEQUENCE; CASPASES; CATALYTIC DOMAIN; CPG ISLANDS; DIOXYGENASES; DNA METHYLATION; DNA-BINDING PROTEINS; DOWN-REGULATION; EMBRYONIC STEM CELLS; ENZYME ACTIVATION; HEK293 CELLS; HUMANS; MICE; OXIDATION-REDUCTION; PROMOTER REGIONS, GENETIC; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; U937 CELLS;

EID: 84877582944     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12052     Document Type: Article

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