Active demethylation in mouse zygotes involves cytosine deamination and base excision repair

Epigenetics and Chromatin

Volumn 6, Issue 1, 2013, Pages

  Santos, Fátima ^a   Peat, Julian ^a   Burgess, Heather ^a,c   Rada, Cristina ^b   Reik, Wolf ^a,c   Dean, Wendy ^a  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

AID; BER; DNA methylation; Epigenetic reprogramming; Hydroxymethylation; TET3; UNG2

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; CYCLINE; CYTOSINE; CYTOSINE DEAMINASE; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3B; ENZYME; FLAP ENDONUCLEASE; FLAP ENDONUCLEASE 1; OXYGENASE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; SINGLE STRANDED DNA; TET3 HYDROXYLASE; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE;

ACTIVE DEMETHYLATION; ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CHROMATIN; CYTOSINE DEAMINATION; DEAMINATION; DEMETHYLATION; DNA END JOINING REPAIR; DNA METHYLATION; DNA REPAIR; DNA REPLICATION; DNA SUPERCOILING; EMBRYO; EMBRYONIC STEM CELL; EXCISION REPAIR; EXPERIMENTAL MOUSE; FEMALE; FLUORESCENCE; GENE MUTATION; HOMOLOGOUS RECOMBINATION; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN GENE; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SOMATIC HYPERMUTATION; THREE DIMENSIONAL IMAGING; ZYGOTE;

MAMMALIA;

EID: 84887354987     PISSN: None     EISSN: 17568935     Source Type: Journal    
DOI: 10.1186/1756-8935-6-39     Document Type: Article

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