메뉴 건너뛰기




Volumn 42, Issue 13, 2014, Pages 8592-8604

TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; DEOXYRIBONUCLEOPROTEIN; DNA GLYCOSYLTRANSFERASE; METHYL CPG BINDING PROTEIN; METHYLCYTOSINE; NEIL1 GLYCOSYLASE; NEIL2 GLYCOSYLASE; NEIL3 GLYCOSYLASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN LIG3; PROTEIN MBD4; REGULATOR PROTEIN; TET PROTEIN; THYMINE DNA GLYCOSYLASE; UNCLASSIFIED DRUG; XRCC1 PROTEIN;

EID: 84905582980     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gku552     Document Type: Article
Times cited : (77)

References (70)
  • 1
    • 0032565753 scopus 로고    scopus 로고
    • Imprinting of the mouse Igf2r gene depends on an intronic CpG island
    • Wutz, A. and Barlow, D.P. (1998) Imprinting of the mouse Igf2r gene depends on an intronic CpG island. Mol. Cell. Endocrinol., 140, 9-14.
    • (1998) Mol. Cell. Endocrinol. , vol.140 , pp. 9-14
    • Wutz, A.1    Barlow, D.P.2
  • 2
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird, A. (2002) DNA methylation patterns and epigenetic memory. Genes Dev., 16, 6-21.
    • (2002) Genes Dev. , vol.16 , pp. 6-21
    • Bird, A.1
  • 3
    • 0023701018 scopus 로고
    • Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
    • Bestor, T., Laudano, A., Mattaliano, R. and Ingram, V. (1988) Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J. Mol. Biol., 203, 971-983.
    • (1988) J. Mol. Biol. , vol.203 , pp. 971-983
    • Bestor, T.1    Laudano, A.2    Mattaliano, R.3    Ingram, V.4
  • 4
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano, M., Bell, D.W., Haber, D.A. and Li, E. (1999) DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell, 99, 247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 5
    • 0035930660 scopus 로고    scopus 로고
    • Dnmt3L and the establishment of maternal genomic imprints
    • Bourc'his, D., Xu, G.L., Lin, C.S., Bollman, B. and Bestor, T.H. (2001) Dnmt3L and the establishment of maternal genomic imprints. Science, 294, 2536-2539.
    • (2001) Science , vol.294 , pp. 2536-2539
    • Bourc'his, D.1    Xu, G.L.2    Lin, C.S.3    Bollman, B.4    Bestor, T.H.5
  • 6
    • 80052461558 scopus 로고    scopus 로고
    • Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
    • Ito, S., Shen, L., Dai, Q., Wu, S.C., Collins, L.B., Swenberg, J.A., He, C. and Zhang, Y. (2011) Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine. Science, 333, 1300-1303.
    • (2011) Science , vol.333 , pp. 1300-1303
    • Ito, S.1    Shen, L.2    Dai, Q.3    Wu, S.C.4    Collins, L.B.5    Swenberg, J.A.6    He, C.7    Zhang, Y.8
  • 7
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis, S. and Heintz, N. (2009) The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science, 324, 929-930.
    • (2009) Science , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 10
    • 66749152204 scopus 로고    scopus 로고
    • Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids
    • Iyer, L.M., Tahiliani, M., Rao, A. and Aravind, L. (2009) Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell Cycle, 8, 1698-1710.
    • (2009) Cell Cycle , vol.8 , pp. 1698-1710
    • Iyer, L.M.1    Tahiliani, M.2    Rao, A.3    Aravind, L.4
  • 14
    • 80054046273 scopus 로고    scopus 로고
    • Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia
    • Konstandin, N., Bultmann, S., Szwagierczak, A., Dufour, A., Ksienzyk, B., Schneider, F., Herold, T., Mulaw, M., Kakadia, P.M., Schneider, S. et al. (2011) Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia. Leukemia, 25, 1649-1652.
    • (2011) Leukemia , vol.25 , pp. 1649-1652
    • Konstandin, N.1    Bultmann, S.2    Szwagierczak, A.3    Dufour, A.4    Ksienzyk, B.5    Schneider, F.6    Herold, T.7    Mulaw, M.8    Kakadia, P.M.9    Schneider, S.10
  • 17
    • 84864722177 scopus 로고    scopus 로고
    • 5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription
    • Kellinger, M.W., Song, C.X., Chong, J., Lu, X.Y., He, C. and Wang, D. (2012) 5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription. Nat. Struct. Mol. Biol., 19, 831-833.
    • (2012) Nat. Struct. Mol. Biol. , vol.19 , pp. 831-833
    • Kellinger, M.W.1    Song, C.X.2    Chong, J.3    Lu, X.Y.4    He, C.5    Wang, D.6
  • 18
    • 80053917872 scopus 로고    scopus 로고
    • Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: Potential implications for active demethylation of CpG sites
    • Maiti, A. and Drohat, A.C. (2011) Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites. J. Biol. Chem., 286, 35334-35338.
    • (2011) J. Biol. Chem. , vol.286 , pp. 35334-35338
    • Maiti, A.1    Drohat, A.C.2
  • 20
    • 80054097425 scopus 로고    scopus 로고
    • Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos
    • Inoue, A. and Zhang, Y. (2011) Replication-dependent loss of 5-hydroxymethylcytosine in mouse preimplantation embryos. Science, 334, 194.
    • (2011) Science , vol.334 , pp. 194
    • Inoue, A.1    Zhang, Y.2
  • 21
    • 79952763586 scopus 로고    scopus 로고
    • Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine
    • Iqbal, K., Jin, S.G., Pfeifer, G.P. and Szabo, P.E. (2011) Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine. Proc. Natl. Acad. Sci. U.S.A., 108, 3642-3647.
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 3642-3647
    • Iqbal, K.1    Jin, S.G.2    Pfeifer, G.P.3    Szabo, P.E.4
  • 22
    • 0033523760 scopus 로고    scopus 로고
    • DNA methyltransferase is actively retained in the cytoplasm during early development
    • Cardoso, M.C. and Leonhardt, H. (1999) DNA methyltransferase is actively retained in the cytoplasm during early development. J. Cell Biol., 147, 25-32.
    • (1999) J. Cell Biol. , vol.147 , pp. 25-32
    • Cardoso, M.C.1    Leonhardt, H.2
  • 23
    • 79955538247 scopus 로고    scopus 로고
    • Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain
    • Guo, J.U., Su, Y., Zhong, C., Ming, G.L. and Song, H. (2011) Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain. Cell, 145, 423-434.
    • (2011) Cell , vol.145 , pp. 423-434
    • Guo, J.U.1    Su, Y.2    Zhong, C.3    Ming, G.L.4    Song, H.5
  • 24
    • 77956095231 scopus 로고    scopus 로고
    • Active DNA demethylation: Many roads lead to Rome
    • Wu, S.C. and Zhang, Y. (2010) Active DNA demethylation: many roads lead to Rome. Nat. Rev. Mol. Cell Biol., 11, 607-620.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 607-620
    • Wu, S.C.1    Zhang, Y.2
  • 25
    • 80052495940 scopus 로고    scopus 로고
    • Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA
    • He, Y.F., Li, B.Z., Li, Z., Liu, P., Wang, Y., Tang, Q., Ding, J., Jia, Y., Chen, Z., Li, L. et al. (2011) Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA. Science, 333, 1303-1307.
    • (2011) Science , vol.333 , pp. 1303-1307
    • He, Y.F.1    Li, B.Z.2    Li, Z.3    Liu, P.4    Wang, Y.5    Tang, Q.6    Ding, J.7    Jia, Y.8    Chen, Z.9    Li, L.10
  • 26
    • 84876393023 scopus 로고    scopus 로고
    • Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair
    • Campalans, A., Kortulewski, T., Amouroux, R., Menoni, H., Vermeulen, W. and Radicella, J.P. (2013) Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair. Nucleic Acids Res., 41, 3115-3129.
    • (2013) Nucleic Acids Res. , vol.41 , pp. 3115-3129
    • Campalans, A.1    Kortulewski, T.2    Amouroux, R.3    Menoni, H.4    Vermeulen, W.5    Radicella, J.P.6
  • 28
    • 33746801232 scopus 로고    scopus 로고
    • Differential recruitment of DNA Ligase i and III to DNA repair sites
    • Mortusewicz, O., Rothbauer, U., Cardoso, M.C. and Leonhardt, H. (2006) Differential recruitment of DNA Ligase I and III to DNA repair sites. Nucleic Acids Res., 34, 3523-3532.
    • (2006) Nucleic Acids Res. , vol.34 , pp. 3523-3532
    • Mortusewicz, O.1    Rothbauer, U.2    Cardoso, M.C.3    Leonhardt, H.4
  • 30
    • 84876946045 scopus 로고    scopus 로고
    • Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics
    • Shen, L., Wu, H., Diep, D., Yamaguchi, S., D'Alessio, A.C., Fung, H.L., Zhang, K. and Zhang, Y. (2013) Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosine oxidation dynamics. Cell, 153, 692-706.
    • (2013) Cell , vol.153 , pp. 692-706
    • Shen, L.1    Wu, H.2    Diep, D.3    Yamaguchi, S.4    D'alessio, A.C.5    Fung, H.L.6    Zhang, K.7    Zhang, Y.8
  • 32
    • 84866887356 scopus 로고    scopus 로고
    • Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: Structural basis and implications for active DNA demethylation
    • Hashimoto, H., Zhang, X. and Cheng, X. (2012) Excision of thymine and 5-hydroxymethyluracil by the MBD4 DNA glycosylase domain: structural basis and implications for active DNA demethylation. Nucleic Acids Res., 40, 8276-8284.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 8276-8284
    • Hashimoto, H.1    Zhang, X.2    Cheng, X.3
  • 33
    • 84864452214 scopus 로고    scopus 로고
    • Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice
    • Kemmerich, K., Dingler, F.A., Rada, C. and Neuberger, M.S. (2012) Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice. Nucleic Acids Res., 40, 6016-6025.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 6016-6025
    • Kemmerich, K.1    Dingler, F.A.2    Rada, C.3    Neuberger, M.S.4
  • 35
  • 39
    • 77956189495 scopus 로고    scopus 로고
    • Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    • Ito, S., D'Alessio, A.C., Taranova, O.V., Hong, K., Sowers, L.C. and Zhang, Y. (2010) Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification. Nature, 466, 1129-1133.
    • (2010) Nature , vol.466 , pp. 1129-1133
    • Ito, S.1    D'alessio, A.C.2    Taranova, O.V.3    Hong, K.4    Sowers, L.C.5    Zhang, Y.6
  • 40
    • 79960273984 scopus 로고    scopus 로고
    • Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5-hydroxymethylcytosine
    • Szwagierczak, A., Brachmann, A., Schmidt, C.S., Bultmann, S., Leonhardt, H. and Spada, F. (2011) Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5-hydroxymethylcytosine. Nucleic Acids Res., 39, 5149-5156.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 5149-5156
    • Szwagierczak, A.1    Brachmann, A.2    Schmidt, C.S.3    Bultmann, S.4    Leonhardt, H.5    Spada, F.6
  • 42
    • 54249144665 scopus 로고    scopus 로고
    • Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins
    • Rottach, A., Kremmer, E., Nowak, D., Leonhardt, H. and Cardoso, M.C. (2008) Generation and characterization of a rat monoclonal antibody specific for multiple red fluorescent proteins. Hybridoma, 27, 337-343.
    • (2008) Hybridoma , vol.27 , pp. 337-343
    • Rottach, A.1    Kremmer, E.2    Nowak, D.3    Leonhardt, H.4    Cardoso, M.C.5
  • 43
    • 57449099865 scopus 로고    scopus 로고
    • Max quant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
    • Cox, J. and Mann, M. (2008) MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification. Nat. Biotechnol., 26, 1367-1372.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1367-1372
    • Cox, J.1    Mann, M.2
  • 44
    • 84886668282 scopus 로고    scopus 로고
    • Visualization and targeted disruption of protein interactions in living cells
    • Herce, H.D., Deng, W., Helma, J., Leonhardt, H. and Cardoso, M.C. (2013) Visualization and targeted disruption of protein interactions in living cells. Nat. Commun., 4, 2660.
    • (2013) Nat. Commun. , vol.4 , pp. 2660
    • Herce, H.D.1    Deng, W.2    Helma, J.3    Leonhardt, H.4    Cardoso, M.C.5
  • 45
    • 84856257194 scopus 로고    scopus 로고
    • The fluorescent two-hybrid (F2H) assay for direct analysis of protein-protein interactions in living cells
    • Zolghadr, K., Rothbauer, U. and Leonhardt, H. (2012) The fluorescent two-hybrid (F2H) assay for direct analysis of protein-protein interactions in living cells. Methods Mol. Biol., 812, 275-282.
    • (2012) Methods Mol. Biol. , vol.812 , pp. 275-282
    • Zolghadr, K.1    Rothbauer, U.2    Leonhardt, H.3
  • 47
    • 0034721829 scopus 로고    scopus 로고
    • Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis
    • Hardeland, U., Bentele, M., Jiricny, J. and Schar, P. (2000) Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis. J. Biol. Chem., 275, 33449-33456.
    • (2000) J. Biol. Chem. , vol.275 , pp. 33449-33456
    • Hardeland, U.1    Bentele, M.2    Jiricny, J.3    Schar, P.4
  • 48
    • 84875436273 scopus 로고    scopus 로고
    • Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant
    • Hashimoto, H., Zhang, X. and Cheng, X. (2013) Selective excision of 5-carboxylcytosine by a thymine DNA glycosylase mutant. J. Mol. Biol., 425, 971-976.
    • (2013) J. Mol. Biol. , vol.425 , pp. 971-976
    • Hashimoto, H.1    Zhang, X.2    Cheng, X.3
  • 49
    • 84869044795 scopus 로고    scopus 로고
    • Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: Its structural basis and implications for active DNA demethylation
    • Hashimoto, H., Hong, S., Bhagwat, A.S., Zhang, X. and Cheng, X. (2012) Excision of 5-hydroxymethyluracil and 5-carboxylcytosine by the thymine DNA glycosylase domain: its structural basis and implications for active DNA demethylation. Nucleic Acids Res., 40, 10203-10214.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 10203-10214
    • Hashimoto, H.1    Hong, S.2    Bhagwat, A.S.3    Zhang, X.4    Cheng, X.5
  • 51
    • 0025314841 scopus 로고
    • Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells
    • Wiebauer, K. and Jiricny, J. (1990) Mismatch-specific thymine DNA glycosylase and DNA polymerase beta mediate the correction of G.T mispairs in nuclear extracts from human cells. Proc. Natl. Acad. Sci. U.S.A., 87, 5842-5845.
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 5842-5845
    • Wiebauer, K.1    Jiricny, J.2
  • 53
    • 84455167621 scopus 로고    scopus 로고
    • Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells
    • Yildirim, O., Li, R., Hung, J.H., Chen, P.B., Dong, X., Ee, L.S., Weng, Z., Rando, O.J. and Fazzio, T.G. (2011) Mbd3/NURD complex regulates expression of 5-hydroxymethylcytosine marked genes in embryonic stem cells. Cell, 147, 1498-1510.
    • (2011) Cell , vol.147 , pp. 1498-1510
    • Yildirim, O.1    Li, R.2    Hung, J.H.3    Chen, P.B.4    Dong, X.5    Ee, L.S.6    Weng, Z.7    Rando, O.J.8    Fazzio, T.G.9
  • 55
    • 84872953223 scopus 로고    scopus 로고
    • TET2 promotes histone O-GlcNAcylation during gene transcription
    • Chen, Q., Chen, Y., Bian, C., Fujiki, R. and Yu, X. (2013) TET2 promotes histone O-GlcNAcylation during gene transcription. Nature, 493, 561-564.
    • (2013) Nature , vol.493 , pp. 561-564
    • Chen, Q.1    Chen, Y.2    Bian, C.3    Fujiki, R.4    Yu, X.5
  • 56
    • 84880530231 scopus 로고    scopus 로고
    • Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells
    • Shi, F.T., Kim, H., Lu, W., He, Q., Liu, D., Goodell, M.A., Wan, M. and Songyang, Z. (2013) Ten-eleven translocation 1 (Tet1) is regulated by O-linked N-acetylglucosamine transferase (Ogt) for target gene repression in mouse embryonic stem cells. J. Biol. Chem., 288, 20776-20784.
    • (2013) J. Biol. Chem. , vol.288 , pp. 20776-20784
    • Shi, F.T.1    Kim, H.2    Lu, W.3    He, Q.4    Liu, D.5    Goodell, M.A.6    Wan, M.7    Songyang, Z.8
  • 57
    • 84896858308 scopus 로고    scopus 로고
    • Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked beta-N-acetylglucosamine transferase (OGT)
    • Zhang, Q., Liu, X., Gao, W., Li, P., Hou, J., Li, J. and Wong, J. (2014) Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked beta-N-acetylglucosamine transferase (OGT). J. Biol. Chem., 289, 5986-5996.
    • (2014) J. Biol. Chem. , vol.289 , pp. 5986-5996
    • Zhang, Q.1    Liu, X.2    Gao, W.3    Li, P.4    Hou, J.5    Li, J.6    Wong, J.7
  • 59
    • 0347379928 scopus 로고    scopus 로고
    • Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2
    • Dou, H., Mitra, S. and Hazra, T.K. (2003) Repair of oxidized bases in DNA bubble structures by human DNA glycosylases NEIL1 and NEIL2. J. Biol. Chem., 278, 49679-49684.
    • (2003) J. Biol. Chem. , vol.278 , pp. 49679-49684
    • Dou, H.1    Mitra, S.2    Hazra, T.K.3
  • 60
    • 0037162995 scopus 로고    scopus 로고
    • Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions
    • Hazra, T.K., Kow, Y.W., Hatahet, Z., Imhoff, B., Boldogh, I., Mokkapati, S.K., Mitra, S. and Izumi, T. (2002) Identification and characterization of a novel human DNA glycosylase for repair of cytosine-derived lesions. J. Biol. Chem., 277, 30417-30420.
    • (2002) J. Biol. Chem. , vol.277 , pp. 30417-30420
    • Hazra, T.K.1    Kow, Y.W.2    Hatahet, Z.3    Imhoff, B.4    Boldogh, I.5    Mokkapati, S.K.6    Mitra, S.7    Izumi, T.8
  • 61
    • 84862758175 scopus 로고    scopus 로고
    • New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs
    • Gibson, B.A. and Kraus, W.L. (2012) New insights into the molecular and cellular functions of poly(ADP-ribose) and PARPs. Nat. Rev. Mol. Cell Biol., 13, 411-424.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 411-424
    • Gibson, B.A.1    Kraus, W.L.2
  • 62
    • 0029842307 scopus 로고    scopus 로고
    • Reconstitution of DNA base excision-repair with purified human proteins: Interaction between DNA polymerase beta and the XRCC1 protein
    • Kubota, Y., Nash, R.A., Klungland, A., Schar, P., Barnes, D.E. and Lindahl, T. (1996) Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein. EMBO J., 15, 6662-6670.
    • (1996) EMBO J. , vol.15 , pp. 6662-6670
    • Kubota, Y.1    Nash, R.A.2    Klungland, A.3    Schar, P.4    Barnes, D.E.5    Lindahl, T.6
  • 63
    • 0032858478 scopus 로고    scopus 로고
    • Holding damaged DNA together
    • Rice, P.A. (1999) Holding damaged DNA together. Nat. Struct. Biol., 6, 805-806.
    • (1999) Nat. Struct. Biol. , vol.6 , pp. 805-806
    • Rice, P.A.1
  • 64
    • 38049007502 scopus 로고    scopus 로고
    • Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells
    • Mortusewicz, O., Ame, J.C., Schreiber, V. and Leonhardt, H. (2007) Feedback-regulated poly(ADP-ribosyl)ation by PARP-1 is required for rapid response to DNA damage in living cells. Nucleic Acids Res., 35, 7665-7675.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 7665-7675
    • Mortusewicz, O.1    Ame, J.C.2    Schreiber, V.3    Leonhardt, H.4
  • 65
    • 84859265962 scopus 로고    scopus 로고
    • Active DNA demethylation by Gadd45 and DNA repair
    • Niehrs, C. and Schafer, A. (2012) Active DNA demethylation by Gadd45 and DNA repair. Trends Cell Biol., 22, 220-227.
    • (2012) Trends Cell Biol. , vol.22 , pp. 220-227
    • Niehrs, C.1    Schafer, A.2
  • 66
    • 0037388165 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase
    • Bransteitter, R., Pham, P., Scharff, M.D. and Goodman, M.F. (2003) Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase. Proc. Natl. Acad. Sci. U.S.A., 100, 4102-4107.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 4102-4107
    • Bransteitter, R.1    Pham, P.2    Scharff, M.D.3    Goodman, M.F.4
  • 67
    • 84887354987 scopus 로고    scopus 로고
    • Active demethylation in mouse zygotes involves cytosine deamination and base excision repair
    • Santos, F., Peat, J., Burgess, H., Rada, C., Reik, W. and Dean, W. (2013) Active demethylation in mouse zygotes involves cytosine deamination and base excision repair. Epigenet. Chromat., 6, 39.
    • (2013) Epigenet. Chromat. , vol.6 , pp. 39
    • Santos, F.1    Peat, J.2    Burgess, H.3    Rada, C.4    Reik, W.5    Dean, W.6
  • 68
  • 69
    • 84859749531 scopus 로고    scopus 로고
    • DNA glycosylases: In DNA repair and beyond
    • Jacobs, A.L. and Schar, P. (2012) DNA glycosylases: in DNA repair and beyond. Chromosoma, 121, 1-20.
    • (2012) Chromosoma , vol.121 , pp. 1-20
    • Jacobs, A.L.1    Schar, P.2
  • 70
    • 32944471308 scopus 로고    scopus 로고
    • Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein
    • Torisu, K., Tsuchimoto, D., Ohnishi, Y. and Nakabeppu, Y. (2005) Hematopoietic tissue-specific expression of mouse Neil3 for endonuclease VIII-like protein. J. Biochem., 138, 763-772.
    • (2005) J. Biochem. , vol.138 , pp. 763-772
    • Torisu, K.1    Tsuchimoto, D.2    Ohnishi, Y.3    Nakabeppu, Y.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.