-
1
-
-
0033771402
-
The superfamily of heptahelical receptors
-
Lefkowitz RJ. The superfamily of heptahelical receptors. Nat Cell Biol. 2000;2:E133-E136.
-
(2000)
Nat Cell Biol
, vol.2
, pp. E133-E136
-
-
Lefkowitz, R.J.1
-
2
-
-
33947356279
-
G protein coupled receptor structure and activation
-
Kobilka BK. G protein coupled receptor structure and activation. Biochim Biophys Acta. 2007;1768:794-807.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 794-807
-
-
Kobilka, B.K.1
-
3
-
-
79952488185
-
Therapeutic potential of betaarrestin-and G protein-biased agonists
-
Whalen EJ, Rajagopal S, Lefkowitz RJ. Therapeutic potential of betaarrestin-and G protein-biased agonists. Trends Mol Med. 2011;17: 126-139.
-
(2011)
Trends Mol Med
, vol.17
, pp. 126-139
-
-
Whalen, E.J.1
Rajagopal, S.2
Lefkowitz, R.J.3
-
4
-
-
17644402459
-
Transduction of receptor signals by betaarrestins
-
Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by betaarrestins. Science. 2005;308:512-517.
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
7
-
-
33947375174
-
Physiological roles of G protein-coupled receptor kinases and arrestins
-
Premont RT, Gainetdinov RR. Physiological roles of G protein-coupled receptor kinases and arrestins. Annu Rev Physiol. 2007;69:511-534.
-
(2007)
Annu Rev Physiol
, vol.69
, pp. 511-534
-
-
Premont, R.T.1
Gainetdinov, R.R.2
-
9
-
-
84945960435
-
Emerging functional divergence of beta-arrestin isoforms in GPCR function
-
Srivastava A, Gupta B, Gupta C, et al. Emerging functional divergence of beta-arrestin isoforms in GPCR function. Trends Endocrinol Metab. 2015;26:628-642.
-
(2015)
Trends Endocrinol Metab
, vol.26
, pp. 628-642
-
-
Srivastava, A.1
Gupta, B.2
Gupta, C.3
-
10
-
-
0035852697
-
Beta-arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
-
Kohout TA, Lin FS, Perry SJ, et al. Beta-arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc Natl Acad Sci U S A. 2001;98:1601-1606.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 1601-1606
-
-
Kohout, T.A.1
Lin, F.S.2
Perry, S.J.3
-
11
-
-
80052038573
-
Beta-arrestin-mediated receptor trafficking and signal transduction
-
Shenoy SK, Lefkowitz RJ. Beta-arrestin-mediated receptor trafficking and signal transduction. Trends Pharmacol Sci. 2011;32:521-533.
-
(2011)
Trends Pharmacol Sci
, vol.32
, pp. 521-533
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
12
-
-
84855901533
-
Molecular mechanism of betaarrestin-biased agonism at seven-transmembrane receptors
-
Reiter E, Ahn S, Shukla AK, et al. Molecular mechanism of betaarrestin-biased agonism at seven-transmembrane receptors. Annu Rev Pharmacol Toxicol. 2012;52:179-197.
-
(2012)
Annu Rev Pharmacol Toxicol
, vol.52
, pp. 179-197
-
-
Reiter, E.1
Ahn, S.2
Shukla, A.K.3
-
13
-
-
0037174646
-
Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins
-
Perry SJ, Baillie GS, Kohout TA, et al. Targeting of cyclic AMP degradation to beta 2-adrenergic receptors by beta-arrestins. Science. 2002; 298:834-836.
-
(2002)
Science
, vol.298
, pp. 834-836
-
-
Perry, S.J.1
Baillie, G.S.2
Kohout, T.A.3
-
14
-
-
0037417890
-
Beta-arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi
-
Baillie GS, Sood A, McPhee I, et al. Beta-arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates beta-adrenoceptor switching from Gs to Gi. Proc Natl Acad Sci U S A. 2003;100:940-945.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 940-945
-
-
Baillie, G.S.1
Sood, A.2
McPhee, I.3
-
15
-
-
38549107922
-
Signaling from beta1-and beta2-adrenergic receptors is defined by differential interactions with PDE4
-
Richter W, Day P, Agrawal R, et al. Signaling from beta1-and beta2-adrenergic receptors is defined by differential interactions with PDE4. EMBO J. 2008;27:384-393.
-
(2008)
EMBO J
, vol.27
, pp. 384-393
-
-
Richter, W.1
Day, P.2
Agrawal, R.3
-
16
-
-
33846834013
-
Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins
-
Nelson CD, Perry SJ, Regier DS, et al. Targeting of diacylglycerol degradation to M1 muscarinic receptors by beta-arrestins. Science. 2007;315:663-666.
-
(2007)
Science
, vol.315
, pp. 663-666
-
-
Nelson, C.D.1
Perry, S.J.2
Regier, D.S.3
-
17
-
-
68949125160
-
Biophysics and function of phosphatidic acid: A molecular perspective
-
Kooijman EE, Burger KN. Biophysics and function of phosphatidic acid: a molecular perspective. Biochim Biophys Acta. 2009;1791: 881-888.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 881-888
-
-
Kooijman, E.E.1
Burger, K.N.2
-
18
-
-
0030593035
-
Role of betaarrestin in mediating agonist-promoted G protein-coupled receptor internalization
-
Ferguson SS, Downey WE III, Colapietro AM, et al. Role of betaarrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science. 1996;271:363-366.
-
(1996)
Science
, vol.271
, pp. 363-366
-
-
Ferguson, S.S.1
Downey, W.E.2
Colapietro, A.M.3
-
19
-
-
0029770657
-
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
-
Goodman OB Jr, Krupnick JG, Santini F, et al. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature. 1996;383:447-450.
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman, O.B.1
Krupnick, J.G.2
Santini, F.3
-
20
-
-
84873411358
-
Distinct roles for beta-arrestin2 and arrestin-domain-containing proteins in beta2 adrenergic receptor trafficking
-
Han SO, Kommaddi RP, Shenoy SK. Distinct roles for beta-arrestin2 and arrestin-domain-containing proteins in beta2 adrenergic receptor trafficking. EMBO Rep. 2013;14:164-171.
-
(2013)
EMBO Rep
, vol.14
, pp. 164-171
-
-
Han, S.O.1
Kommaddi, R.P.2
Shenoy, S.K.3
-
21
-
-
85007355267
-
Chapter one-ubiquitination and deubiquitination of G protein-coupled receptors
-
Jean-Charles PY, Snyder JC, Shenoy SK. Chapter one-ubiquitination and deubiquitination of G protein-coupled receptors. Prog Mol Biol Transl Sci. 2016;141:1-55.
-
(2016)
Prog Mol Biol Transl Sci
, vol.141
, pp. 1-55
-
-
Jean-Charles, P.Y.1
Snyder, J.C.2
Shenoy, S.K.3
-
23
-
-
0035834428
-
Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and betaarrestin
-
Shenoy SK, McDonald PH, Kohout TA, et al. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and betaarrestin. Science. 2001;294:1307-1313.
-
(2001)
Science
, vol.294
, pp. 1307-1313
-
-
Shenoy, S.K.1
McDonald, P.H.2
Kohout, T.A.3
-
24
-
-
52049117442
-
Nedd4 mediates agonistdependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor
-
Shenoy SK, Xiao K, Venkataramanan V, et al. Nedd4 mediates agonistdependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. J Biol Chem. 2008;283:22166-22176.
-
(2008)
J Biol Chem
, vol.283
, pp. 22166-22176
-
-
Shenoy, S.K.1
Xiao, K.2
Venkataramanan, V.3
-
25
-
-
84879088145
-
Arrestins as regulators of kinases and phosphatases
-
Luttrell LM, Miller WE. Arrestins as regulators of kinases and phosphatases. Prog Mol Biol Transl Sci. 2013;118:115-147.
-
(2013)
Prog Mol Biol Transl Sci
, vol.118
, pp. 115-147
-
-
Luttrell, L.M.1
Miller, W.E.2
-
26
-
-
84871997357
-
MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound beta(2)-adrenergic receptors
-
Han SO, Xiao K, Kim J, et al. MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound beta(2)-adrenergic receptors. J Cell Biol. 2012;199:817-830.
-
(2012)
J Cell Biol
, vol.199
, pp. 817-830
-
-
Han, S.O.1
Xiao, K.2
Kim, J.3
-
27
-
-
34447649922
-
Beta-arrestin-biased ligands at seventransmembrane receptors
-
Violin JD, Lefkowitz RJ. Beta-arrestin-biased ligands at seventransmembrane receptors. Trends Pharmacol Sci. 2007;28:416-422.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 416-422
-
-
Violin, J.D.1
Lefkowitz, R.J.2
-
28
-
-
84896703861
-
Minireview: More than just a hammer: Ligand bias and pharmaceutical discovery
-
Luttrell LM. Minireview: more than just a hammer: ligand bias and pharmaceutical discovery. Mol Endocrinol. 2014;28:281-294.
-
(2014)
Mol Endocrinol
, vol.28
, pp. 281-294
-
-
Luttrell, L.M.1
-
30
-
-
84962459565
-
The conformational signature of beta-arrestin2 predicts its trafficking and signalling functions
-
Lee MH, Appleton KM, Strungs EG, et al. The conformational signature of beta-arrestin2 predicts its trafficking and signalling functions. Nature. 2016;531:665-668.
-
(2016)
Nature
, vol.531
, pp. 665-668
-
-
Lee, M.H.1
Appleton, K.M.2
Strungs, E.G.3
-
31
-
-
84941048021
-
Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR
-
Yang F, Yu X, Liu C, et al. Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and (19)F-NMR. Nat Commun. 2015;6:8202.
-
(2015)
Nat Commun
, vol.6
, pp. 8202
-
-
Yang, F.1
Yu, X.2
Liu, C.3
-
32
-
-
84962420929
-
Beta-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle
-
Nuber S, Zabel U, Lorenz K, et al. beta-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle. Nature. 2016;531:661-664.
-
(2016)
Nature
, vol.531
, pp. 661-664
-
-
Nuber, S.1
Zabel, U.2
Lorenz, K.3
-
33
-
-
0033527663
-
Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
-
Oakley RH, Laporte SA, Holt JA, et al. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem. 1999;274:32248-32257.
-
(1999)
J Biol Chem
, vol.274
, pp. 32248-32257
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
-
34
-
-
0034595860
-
Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors
-
Oakley RH, Laporte SA, Holt JA, et al. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem. 2000;275: 17201-17210.
-
(2000)
J Biol Chem
, vol.275
, pp. 17201-17210
-
-
Oakley, R.H.1
Laporte, S.A.2
Holt, J.A.3
-
35
-
-
9144253232
-
Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2
-
Wei H, Ahn S, Barnes WG, et al. Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2. J Biol Chem. 2004;279:48255-48261.
-
(2004)
J Biol Chem
, vol.279
, pp. 48255-48261
-
-
Wei, H.1
Ahn, S.2
Barnes, W.G.3
-
36
-
-
57649138443
-
Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization
-
Krasel C, Zabel U, Lorenz K, et al. Dual role of the beta2-adrenergic receptor C terminus for the binding of beta-arrestin and receptor internalization. J Biol Chem. 2008;283:31840-31848.
-
(2008)
J Biol Chem
, vol.283
, pp. 31840-31848
-
-
Krasel, C.1
Zabel, U.2
Lorenz, K.3
-
37
-
-
33751509646
-
A phosphorylation cluster of five serine and threonine residues in the C-terminus of the folliclestimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation
-
Kara E, Crepieux P, Gauthier C, et al. A phosphorylation cluster of five serine and threonine residues in the C-terminus of the folliclestimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation. Mol Endocrinol. 2006;20: 3014-3026.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 3014-3026
-
-
Kara, E.1
Crepieux, P.2
Gauthier, C.3
-
38
-
-
79957663678
-
Ligand-dependent mechanisms of sst2A receptor trafficking: Role of site-specific phosphorylation and receptor activation in the actions of biased somatostatin agonists
-
Kao YJ, Ghosh M, Schonbrunn A. Ligand-dependent mechanisms of sst2A receptor trafficking: role of site-specific phosphorylation and receptor activation in the actions of biased somatostatin agonists. Mol Endocrinol. 2011;25:1040-1054.
-
(2011)
Mol Endocrinol
, vol.25
, pp. 1040-1054
-
-
Kao, Y.J.1
Ghosh, M.2
Schonbrunn, A.3
-
39
-
-
45749126997
-
Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences
-
Jones BW, Hinkle PM. Arrestin binds to different phosphorylated regions of the thyrotropin-releasing hormone receptor with distinct functional consequences. Mol Pharmacol. 2008;74:195-202.
-
(2008)
Mol Pharmacol
, vol.74
, pp. 195-202
-
-
Jones, B.W.1
Hinkle, P.M.2
-
40
-
-
1542349921
-
The role of phosphorylation in D1 dopamine receptor desensitization: Evidence for a novel mechanism of arrestin association
-
Kim OJ, Gardner BR, Williams DB, et al. The role of phosphorylation in D1 dopamine receptor desensitization: evidence for a novel mechanism of arrestin association. J Biol Chem. 2004;279:7999-8010.
-
(2004)
J Biol Chem
, vol.279
, pp. 7999-8010
-
-
Kim, O.J.1
Gardner, B.R.2
Williams, D.B.3
-
41
-
-
84963864551
-
Distinct phosphorylation clusters determine the signaling outcome of free fatty acid receptor 4/g protein-coupled receptor 120
-
Prihandoko R, Alvarez-Curto E, Hudson BD, et al. Distinct phosphorylation clusters determine the signaling outcome of free fatty acid receptor 4/g protein-coupled receptor 120. Mol Pharmacol. 2016;89:505-520.
-
(2016)
Mol Pharmacol
, vol.89
, pp. 505-520
-
-
Prihandoko, R.1
Alvarez-Curto, E.2
Hudson, B.D.3
-
42
-
-
84916886215
-
Identification and functional characterization of the phosphorylation sites of the neuropeptide FF2 receptor
-
Bray L, Froment C, Pardo P, et al. Identification and functional characterization of the phosphorylation sites of the neuropeptide FF2 receptor. J Biol Chem. 2014;289:33754-33766.
-
(2014)
J Biol Chem
, vol.289
, pp. 33754-33766
-
-
Bray, L.1
Froment, C.2
Pardo, P.3
-
43
-
-
40349088827
-
G-protein-coupled receptor phosphorylation: Where, when and by whom
-
Tobin AB. G-protein-coupled receptor phosphorylation: where, when and by whom. Br J Pharmacol. 2008;153(suppl 1):S167-S176.
-
(2008)
Br J Pharmacol
, vol.153
, pp. S167-S176
-
-
Tobin, A.B.1
-
44
-
-
79953192547
-
Differential G-proteincoupled receptor phosphorylation provides evidence for a signaling bar code
-
Butcher AJ, Prihandoko R, Kong KC, et al. Differential G-proteincoupled receptor phosphorylation provides evidence for a signaling bar code. J Biol Chem. 2011;286:11506-11518.
-
(2011)
J Biol Chem
, vol.286
, pp. 11506-11518
-
-
Butcher, A.J.1
Prihandoko, R.2
Kong, K.C.3
-
45
-
-
80051625665
-
Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection
-
Lau EK, Trester-Zedlitz M, Trinidad JC, et al. Quantitative encoding of the effect of a partial agonist on individual opioid receptors by multisite phosphorylation and threshold detection. Sci Signal. 2011;4:ra52.
-
(2011)
Sci Signal
, vol.4
, pp. ra52
-
-
Lau, E.K.1
Trester-Zedlitz, M.2
Trinidad, J.C.3
-
46
-
-
13444291851
-
Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling
-
Kim J, Ahn S, Ren XR, et al. Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling. Proc Natl Acad Sci U S A. 2005;102:1442-1447.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1442-1447
-
-
Kim, J.1
Ahn, S.2
Ren, X.R.3
-
47
-
-
13444270337
-
Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor
-
Ren XR, Reiter E, Ahn S, et al. Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor. Proc Natl Acad Sci U S A. 2005;102:1448-1453.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1448-1453
-
-
Ren, X.R.1
Reiter, E.2
Ahn, S.3
-
48
-
-
67649856866
-
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
-
Zidar DA, Violin JD, Whalen EJ, et al. Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands. Proc Natl Acad Sci U S A. 2009;106:9649-9654.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 9649-9654
-
-
Zidar, D.A.1
Violin, J.D.2
Whalen, E.J.3
-
49
-
-
80051616441
-
Distinct phosphorylation sites on the beta(2)-adrenergic receptor establish a barcode that encodes differential functions of beta-arrestin
-
Nobles KN, Xiao K, Ahn S, et al. Distinct phosphorylation sites on the beta(2)-adrenergic receptor establish a barcode that encodes differential functions of beta-arrestin. Sci Signal. 2011;4:ra51.
-
(2011)
Sci Signal
, vol.4
, pp. ra51
-
-
Nobles, K.N.1
Xiao, K.2
Ahn, S.3
-
50
-
-
77951230331
-
Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling
-
Busillo JM, Armando S, Sengupta R, et al. Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J Biol Chem. 2010;285:7805-7817.
-
(2010)
J Biol Chem
, vol.285
, pp. 7805-7817
-
-
Busillo, J.M.1
Armando, S.2
Sengupta, R.3
-
51
-
-
85005965121
-
Distinct cortical and striatal actions of a beta-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties
-
Urs NM, Gee SM, Pack TF, et al. Distinct cortical and striatal actions of a beta-arrestin-biased dopamine D2 receptor ligand reveal unique antipsychotic-like properties. Proc Natl Acad Sci U S A. 2016;113: E8178-E8186.
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E8178-E8186
-
-
Urs, N.M.1
Gee, S.M.2
Pack, T.F.3
-
52
-
-
84877581626
-
Structure of active betaarrestin-1 bound to a G-protein-coupled receptor phosphopeptide
-
Shukla AK, Manglik A, Kruse AC, et al. Structure of active betaarrestin-1 bound to a G-protein-coupled receptor phosphopeptide. Nature. 2013;497:137-141.
-
(2013)
Nature
, vol.497
, pp. 137-141
-
-
Shukla, A.K.1
Manglik, A.2
Kruse, A.C.3
-
53
-
-
84975062691
-
Ubiquitin-related roles of betaarrestins in endocytic trafficking and signal transduction
-
Jean-Charles PY, Rajiv V, Shenoy SK. Ubiquitin-related roles of betaarrestins in endocytic trafficking and signal transduction. J Cell Physiol. 2016;231:2071-2080.
-
(2016)
J Cell Physiol
, vol.231
, pp. 2071-2080
-
-
Jean-Charles, P.Y.1
Rajiv, V.2
Shenoy, S.K.3
-
54
-
-
84965169006
-
Ubiquitin-specific protease 20 regulates the reciprocal functions of beta-arrestin2 in Toll-like receptor 4-promoted nuclear factor kappaB (NFkappaB) activation
-
Jean-Charles PY, Zhang L, Wu JH, et al. Ubiquitin-specific protease 20 regulates the reciprocal functions of beta-arrestin2 in Toll-like receptor 4-promoted nuclear factor kappaB (NFkappaB) activation. J Biol Chem. 2016;291:7450-7464.
-
(2016)
J Biol Chem
, vol.291
, pp. 7450-7464
-
-
Jean-Charles, P.Y.1
Zhang, L.2
Wu, J.H.3
-
55
-
-
0033613938
-
Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes
-
Luttrell LM, Ferguson SS, Daaka Y, et al. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science. 1999;283:655-661.
-
(1999)
Science
, vol.283
, pp. 655-661
-
-
Luttrell, L.M.1
Ferguson, S.S.2
Daaka, Y.3
-
56
-
-
0034689003
-
Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2
-
DeFea KA, Zalevsky J, Thoma MS, et al. Beta-arrestin-dependent endocytosis of proteinase-activated receptor 2 is required for intracellular targeting of activated ERK1/2. J Cell Biol. 2000;148:1267-1281.
-
(2000)
J Cell Biol
, vol.148
, pp. 1267-1281
-
-
DeFea, K.A.1
Zalevsky, J.2
Thoma, M.S.3
-
57
-
-
0035956983
-
Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds
-
Luttrell LM, Roudabush FL, Choy EW, et al. Activation and targeting of extracellular signal-regulated kinases by beta-arrestin scaffolds. Proc Natl Acad Sci U S A. 2001;98:2449-2454.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 2449-2454
-
-
Luttrell, L.M.1
Roudabush, F.L.2
Choy, E.W.3
-
58
-
-
0034711397
-
Beta-arrestin 2: A receptorregulated MAPK scaffold for the activation of JNK3
-
McDonald PH, Chow CW, Miller WE, et al. Beta-arrestin 2: a receptorregulated MAPK scaffold for the activation of JNK3. Science. 2000; 290:1574-1577.
-
(2000)
Science
, vol.290
, pp. 1574-1577
-
-
McDonald, P.H.1
Chow, C.W.2
Miller, W.E.3
-
59
-
-
84975484151
-
Chapter three-ubiquitination, protein turnover of g-proteincoupled receptor kinases in GPCR signaling and cellular regulation
-
Penela P. Chapter three-ubiquitination, protein turnover of g-proteincoupled receptor kinases in GPCR signaling and cellular regulation. Prog Mol Biol Transl Sci. 2016;141:85-140.
-
(2016)
Prog Mol Biol Transl Sci
, vol.141
, pp. 85-140
-
-
Penela, P.1
-
60
-
-
5944221106
-
Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI
-
Barlic J, Andrews JD, Kelvin AA, et al. Regulation of tyrosine kinase activation and granule release through beta-arrestin by CXCRI. Nat Immunol. 2000;1:227-233.
-
(2000)
Nat Immunol
, vol.1
, pp. 227-233
-
-
Barlic, J.1
Andrews, J.D.2
Kelvin, A.A.3
-
61
-
-
84959245777
-
Beta-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation
-
Eichel K, Jullie D, von Zastrow M. Beta-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation. Nat Cell Biol. 2016;18:303-310.
-
(2016)
Nat Cell Biol
, vol.18
, pp. 303-310
-
-
Eichel, K.1
Jullie, D.2
Von Zastrow, M.3
-
62
-
-
35748944113
-
Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation
-
Shenoy SK, Barak LS, Xiao K, et al. Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. J Biol Chem. 2007;282:29549-29562.
-
(2007)
J Biol Chem
, vol.282
, pp. 29549-29562
-
-
Shenoy, S.K.1
Barak, L.S.2
Xiao, K.3
-
63
-
-
17144364766
-
Receptor-specific ubiquitination of betaarrestin directs assembly and targeting of seven-transmembrane receptor signalosomes
-
Shenoy SK, Lefkowitz RJ. Receptor-specific ubiquitination of betaarrestin directs assembly and targeting of seven-transmembrane receptor signalosomes. J Biol Chem. 2005;280:15315-15324.
-
(2005)
J Biol Chem
, vol.280
, pp. 15315-15324
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
64
-
-
0037458614
-
The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation
-
Tohgo A, Choy EW, Gesty-Palmer D, et al. The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation. J Biol Chem. 2003;278:6258-6267.
-
(2003)
J Biol Chem
, vol.278
, pp. 6258-6267
-
-
Tohgo, A.1
Choy, E.W.2
Gesty-Palmer, D.3
-
65
-
-
0037737763
-
Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination
-
Shenoy SK, Lefkowitz RJ. Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. J Biol Chem. 2003;278:14498-14506.
-
(2003)
J Biol Chem
, vol.278
, pp. 14498-14506
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
66
-
-
66149116039
-
Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
-
Shenoy SK, Modi AS, Shukla AK, et al. Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proc Natl Acad Sci U S A. 2009;106:6650-6655.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 6650-6655
-
-
Shenoy, S.K.1
Modi, A.S.2
Shukla, A.K.3
-
67
-
-
84958547196
-
Arrestin-dependent activation of JNK family kinases
-
Zhan X, Kook S, Gurevich EV, et al. Arrestin-dependent activation of JNK family kinases. Handb Exp Pharmacol. 2014;219:259-280.
-
(2014)
Handb Exp Pharmacol
, vol.219
, pp. 259-280
-
-
Zhan, X.1
Kook, S.2
Gurevich, E.V.3
-
68
-
-
84887088263
-
Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins
-
Iacovelli L, Felicioni M, Nistico R, et al. Selective regulation of recombinantly expressed mGlu7 metabotropic glutamate receptors by G protein-coupled receptor kinases and arrestins. Neuropharmacology. 2014;77:303-312.
-
(2014)
Neuropharmacology
, vol.77
, pp. 303-312
-
-
Iacovelli, L.1
Felicioni, M.2
Nistico, R.3
-
69
-
-
0037147145
-
Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation
-
Sun Y, Cheng Z, Ma L, et al. Beta-arrestin2 is critically involved in CXCR4-mediated chemotaxis, and this is mediated by its enhancement of p38 MAPK activation. J Biol Chem. 2002;277:49212-49219.
-
(2002)
J Biol Chem
, vol.277
, pp. 49212-49219
-
-
Sun, Y.1
Cheng, Z.2
Ma, L.3
-
70
-
-
57649186957
-
A novel protein kinase A-independent, betaarrestin-1-dependent signaling pathway for p38 mitogen-activatedprotein kinase activation by beta2-adrenergic receptors
-
Gong K, Li Z, Xu M, et al. A novel protein kinase A-independent, betaarrestin-1-dependent signaling pathway for p38 mitogen-activatedprotein kinase activation by beta2-adrenergic receptors. J Biol Chem. 2008;283:29028-29036.
-
(2008)
J Biol Chem
, vol.283
, pp. 29028-29036
-
-
Gong, K.1
Li, Z.2
Xu, M.3
-
71
-
-
33745832645
-
Kappa opioid receptor activation of p38 MAPK is GRK3-and arrestin-dependent in neurons and astrocytes
-
Bruchas MR, Macey TA, Lowe JD, et al. Kappa opioid receptor activation of p38 MAPK is GRK3-and arrestin-dependent in neurons and astrocytes. J Biol Chem. 2006;281:18081-18089.
-
(2006)
J Biol Chem
, vol.281
, pp. 18081-18089
-
-
Bruchas, M.R.1
Macey, T.A.2
Lowe, J.D.3
-
72
-
-
35548997505
-
Stress-induced p38 mitogenactivated protein kinase activation mediates kappa-opioid-dependent dysphoria
-
Bruchas MR, Land BB, Aita M, et al. Stress-induced p38 mitogenactivated protein kinase activation mediates kappa-opioid-dependent dysphoria. J Neurosci. 2007;27:11614-11623.
-
(2007)
J Neurosci
, vol.27
, pp. 11614-11623
-
-
Bruchas, M.R.1
Land, B.B.2
Aita, M.3
-
73
-
-
77956712828
-
Beta-arrestin inhibits CAMKKbetadependent AMPK activation downstream of protease-activated-receptor-2
-
Wang P, Jiang Y, Wang Y, et al. Beta-arrestin inhibits CAMKKbetadependent AMPK activation downstream of protease-activated-receptor-2. BMC Biochem. 2010;11:36.
-
(2010)
BMC Biochem
, vol.11
, pp. 36
-
-
Wang, P.1
Jiang, Y.2
Wang, Y.3
-
74
-
-
70349646820
-
An arrestin-dependent multi-kinase signaling complex mediates MIP-1beta/CCL4 signaling and chemotaxis of primary human macrophages
-
Cheung R, Malik M, Ravyn V, et al. An arrestin-dependent multi-kinase signaling complex mediates MIP-1beta/CCL4 signaling and chemotaxis of primary human macrophages. J Leukoc Biol. 2009;86:833-845.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 833-845
-
-
Cheung, R.1
Malik, M.2
Ravyn, V.3
-
75
-
-
0036962405
-
Beta-arrestin 1 couples thrombin to the rapid activation of the Akt pathway
-
Goel R, Baldassare JJ. Beta-arrestin 1 couples thrombin to the rapid activation of the Akt pathway. Ann N Y Acad Sci. 2002;973:138-141.
-
(2002)
Ann N y Acad Sci
, vol.973
, pp. 138-141
-
-
Goel, R.1
Baldassare, J.J.2
-
76
-
-
61849088939
-
C-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and-dependent mechanisms
-
Lodeiro M, Theodoropoulou M, Pardo M, et al. c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and-dependent mechanisms. PLoS One. 2009;4:e4686.
-
(2009)
PLoS One
, vol.4
, pp. e4686
-
-
Lodeiro, M.1
Theodoropoulou, M.2
Pardo, M.3
-
77
-
-
79960091427
-
Myocardial AKT: The omnipresent nexus
-
Sussman MA, Volkers M, Fischer K, et al. Myocardial AKT: the omnipresent nexus. Physiol Rev. 2011;91:1023-1070.
-
(2011)
Physiol Rev
, vol.91
, pp. 1023-1070
-
-
Sussman, M.A.1
Volkers, M.2
Fischer, K.3
-
78
-
-
84901455907
-
The physical association of the P2Y12 receptor with PAR4 regulates arrestin-mediated Akt activation
-
Khan A, Li D, Ibrahim S, et al. The physical association of the P2Y12 receptor with PAR4 regulates arrestin-mediated Akt activation. Mol Pharmacol. 2014;86:1-11.
-
(2014)
Mol Pharmacol.
, vol.86
, pp. 1-11
-
-
Khan, A.1
Li, D.2
Ibrahim, S.3
-
79
-
-
67649797371
-
{Beta}-arrestin-2 mediates antiapoptotic signaling through regulation of BAD phosphorylation
-
Ahn S, Kim J, Hara MR, et al. {Beta}-Arrestin-2 mediates antiapoptotic signaling through regulation of BAD phosphorylation. J Biol Chem. 2009;284:8855-8865.
-
(2009)
J Biol Chem
, vol.284
, pp. 8855-8865
-
-
Ahn, S.1
Kim, J.2
Hara, M.R.3
-
80
-
-
84907211040
-
Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis
-
Kendall RT, Lee MH, Pleasant DL, et al. Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis. J Biol Chem. 2014;289:26155-26166.
-
(2014)
J Biol Chem
, vol.289
, pp. 26155-26166
-
-
Kendall, R.T.1
Lee, M.H.2
Pleasant, D.L.3
-
81
-
-
80052832196
-
A stress response pathway regulates DNA damage through beta2-adrenoreceptors and beta-arrestin-1
-
Hara MR, Kovacs JJ, Whalen EJ, et al. A stress response pathway regulates DNA damage through beta2-adrenoreceptors and beta-arrestin-1. Nature. 2011;477:349-353.
-
(2011)
Nature
, vol.477
, pp. 349-353
-
-
Hara, M.R.1
Kovacs, J.J.2
Whalen, E.J.3
-
82
-
-
37649023273
-
A beta-arrestin 2 signaling complex mediates lithium action on behavior
-
Beaulieu JM, Marion S, Rodriguiz RM, et al. A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell. 2008;132:125-136.
-
(2008)
Cell
, vol.132
, pp. 125-136
-
-
Beaulieu, J.M.1
Marion, S.2
Rodriguiz, R.M.3
-
84
-
-
80052346263
-
Glycogen synthase kinase-3 is essential for beta-arrestin-2 complex formation and lithium-sensitive behaviors in mice
-
O'Brien WT, Huang J, Buccafusca R, et al. Glycogen synthase kinase-3 is essential for beta-arrestin-2 complex formation and lithium-sensitive behaviors in mice. J Clin Invest. 2011;121:3756-3762.
-
(2011)
J Clin Invest
, vol.121
, pp. 3756-3762
-
-
O'Brien, W.T.1
Huang, J.2
Buccafusca, R.3
-
85
-
-
84984596161
-
PAR2-dependent activation of GSK3beta regulates the survival of colon stem/progenitor cells
-
Nasri I, Bonnet D, Zwarycz B, et al. PAR2-dependent activation of GSK3beta regulates the survival of colon stem/progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2016;311:G221-G236.
-
(2016)
Am J Physiol Gastrointest Liver Physiol
, vol.311
, pp. G221-G236
-
-
Nasri, I.1
Bonnet, D.2
Zwarycz, B.3
-
86
-
-
84926162022
-
Neuropeptide y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor
-
Lecat S, Belemnaba L, Galzi JL, et al. Neuropeptide Y receptor mediates activation of ERK1/2 via transactivation of the IGF receptor. Cell Signal. 2015;27:1297-1304.
-
(2015)
Cell Signal
, vol.27
, pp. 1297-1304
-
-
Lecat, S.1
Belemnaba, L.2
Galzi, J.L.3
-
87
-
-
84969130046
-
Beta-arrestin-2 counters CXCR7-mediated EGFR transactivation and proliferation
-
Kallifatidis G, Munoz D, Singh RK, et al. Beta-arrestin-2 counters CXCR7-mediated EGFR transactivation and proliferation. Mol Cancer Res. 2016;14:493-503.
-
(2016)
Mol Cancer Res
, vol.14
, pp. 493-503
-
-
Kallifatidis, G.1
Munoz, D.2
Singh, R.K.3
-
88
-
-
84886021055
-
Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P1/S1P3-dependent beta-arrestin/c-Src pathways
-
Ryu JM, Baek YB, Shin MS, et al. Sphingosine-1-phosphate-induced Flk-1 transactivation stimulates mouse embryonic stem cell proliferation through S1P1/S1P3-dependent beta-arrestin/c-Src pathways. Stem Cell Res. 2014;12:69-85.
-
(2014)
Stem Cell Res
, vol.12
, pp. 69-85
-
-
Ryu, J.M.1
Baek, Y.B.2
Shin, M.S.3
-
89
-
-
34848820302
-
Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection
-
Noma T, Lemaire A, Naga Prasad SV, et al. Beta-arrestin-mediated beta1-adrenergic receptor transactivation of the EGFR confers cardioprotection. J Clin Invest. 2007;117:2445-2458.
-
(2007)
J Clin Invest
, vol.117
, pp. 2445-2458
-
-
Noma, T.1
Lemaire, A.2
Naga Prasad, S.V.3
-
90
-
-
84957110055
-
Alpha1a-Adrenoceptor genetic variant triggers vascular smooth muscle cell hyperproliferation and agonist induced hypertrophy via EGFR transactivation pathway
-
Gradinaru I, Babaeva E, Schwinn DA, et al. Alpha1a-Adrenoceptor genetic variant triggers vascular smooth muscle cell hyperproliferation and agonist induced hypertrophy via EGFR transactivation pathway. PLoS One. 2015;10:e0142787.
-
(2015)
PLoS One
, vol.10
, pp. e0142787
-
-
Gradinaru, I.1
Babaeva, E.2
Schwinn, D.A.3
-
91
-
-
62449145673
-
Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis
-
Rosano L, Cianfrocca R, Masi S, et al. Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis. Proc Natl Acad Sci U S A. 2009;106:2806-2811.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2806-2811
-
-
Rosano, L.1
Cianfrocca, R.2
Masi, S.3
-
92
-
-
79959783092
-
EGFR trans-activation by urotensin II receptor is mediated by beta-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy
-
Esposito G, Perrino C, Cannavo A, et al. EGFR trans-activation by urotensin II receptor is mediated by beta-arrestin recruitment and confers cardioprotection in pressure overload-induced cardiac hypertrophy. Basic Res Cardiol. 2011;106:577-589.
-
(2011)
Basic Res Cardiol
, vol.106
, pp. 577-589
-
-
Esposito, G.1
Perrino, C.2
Cannavo, A.3
-
93
-
-
84954401886
-
Beta-arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells
-
Santos-Zas I, Gurriaran-Rodriguez U, Cid-Diaz T, et al. Beta-arrestin scaffolds and signaling elements essential for the obestatin/GPR39 system that determine the myogenic program in human myoblast cells. Cell Mol Life Sci. 2016;73:617-635.
-
(2016)
Cell Mol Life Sci
, vol.73
, pp. 617-635
-
-
Santos-Zas, I.1
Gurriaran-Rodriguez, U.2
Cid-Diaz, T.3
-
94
-
-
79959610178
-
GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness
-
Zajac M, Law J, Cvetkovic DD, et al. GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness. PLoS One. 2011;6: e21599.
-
(2011)
PLoS One
, vol.6
, pp. e21599
-
-
Zajac, M.1
Law, J.2
Cvetkovic, D.D.3
-
95
-
-
2942751868
-
Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
-
Zou Y, Akazawa H, Qin Y, et al. Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II. Nat Cell Biol. 2004;6:499-506.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 499-506
-
-
Zou, Y.1
Akazawa, H.2
Qin, Y.3
-
96
-
-
0027722248
-
Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro
-
Sadoshima J, Xu Y, Slayter HS, et al. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell. 1993;75:977-984.
-
(1993)
Cell
, vol.75
, pp. 977-984
-
-
Sadoshima, J.1
Xu, Y.2
Slayter, H.S.3
-
97
-
-
77953819826
-
Beta-arrestin-biased agonism of the angiotensin receptor induced by mechanical stress
-
Rakesh K, Yoo B, Kim IM, et al. Beta-arrestin-biased agonism of the angiotensin receptor induced by mechanical stress. Sci Signal. 2010;3: ra46.
-
(2010)
Sci Signal
, vol.3
, pp. ra46
-
-
Rakesh, K.1
Yoo, B.2
Kim, I.M.3
-
98
-
-
84899441356
-
Src is required for mechanical stretchinduced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent beta-arrestin2 pathways
-
Wang S, Gong H, Jiang G, et al. Src is required for mechanical stretchinduced cardiomyocyte hypertrophy through angiotensin II type 1 receptor-dependent beta-arrestin2 pathways. PLoS One. 2014;9:e92926.
-
(2014)
PLoS One
, vol.9
, pp. e92926
-
-
Wang, S.1
Gong, H.2
Jiang, G.3
-
99
-
-
84946046817
-
The role of beta-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome
-
Wisler JW, Harris EM, Raisch M, et al. The role of beta-arrestin2-dependent signaling in thoracic aortic aneurysm formation in a murine model of Marfan syndrome. Am J Physiol Heart Circ Physiol. 2015; 309:H1516-H1527.
-
(2015)
Am J Physiol Heart Circ Physiol
, vol.309
, pp. H1516-H1527
-
-
Wisler, J.W.1
Harris, E.M.2
Raisch, M.3
-
100
-
-
84877576407
-
Beta-arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice
-
Trivedi DB, Loftin CD, Clark J, et al. Beta-arrestin-2 deficiency attenuates abdominal aortic aneurysm formation in mice. Circ Res. 2013;112: 1219-1229.
-
(2013)
Circ Res
, vol.112
, pp. 1219-1229
-
-
Trivedi, D.B.1
Loftin, C.D.2
Clark, J.3
-
102
-
-
84912083325
-
G Protein and beta-arrestin signaling bias at the ghrelin receptor
-
Evron T, Peterson SM, Urs NM, et al. G Protein and beta-arrestin signaling bias at the ghrelin receptor. J Biol Chem. 2014;289:33442-33455.
-
(2014)
J Biol Chem
, vol.289
, pp. 33442-33455
-
-
Evron, T.1
Peterson, S.M.2
Urs, N.M.3
-
103
-
-
84861740318
-
Acute activation of beta2-adrenergic receptor regulates focal adhesions through betaArrestin2-and p115Rho-GEF protein-mediated activation of RhoA
-
Ma X, Zhao Y, Daaka Y, et al. Acute activation of beta2-adrenergic receptor regulates focal adhesions through betaArrestin2-and p115Rho-GEF protein-mediated activation of RhoA. J Biol Chem. 2012;287: 18925-18936.
-
(2012)
J Biol Chem
, vol.287
, pp. 18925-18936
-
-
Ma, X.1
Zhao, Y.2
Daaka, Y.3
-
104
-
-
18544379729
-
Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization
-
Bhattacharya M, Anborgh PH, Babwah AV, et al. Beta-arrestins regulate a Ral-GDS Ral effector pathway that mediates cytoskeletal reorganization. Nat Cell Biol. 2002;4:547-555.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 547-555
-
-
Bhattacharya, M.1
Anborgh, P.H.2
Babwah, A.V.3
-
105
-
-
14844338481
-
Beta-arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation
-
Barnes WG, Reiter E, Violin JD, et al. Beta-arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. J Biol Chem. 2005;280:8041-8050.
-
(2005)
J Biol Chem
, vol.280
, pp. 8041-8050
-
-
Barnes, W.G.1
Reiter, E.2
Violin, J.D.3
-
106
-
-
79952265050
-
Beta-arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation
-
Anthony DF, Sin YY, Vadrevu S, et al. Beta-arrestin 1 inhibits the GTPase-activating protein function of ARHGAP21, promoting activation of RhoA following angiotensin II type 1A receptor stimulation. Mol Cell Biol. 2011;31:1066-1075.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 1066-1075
-
-
Anthony, D.F.1
Sin, Y.Y.2
Vadrevu, S.3
-
107
-
-
77952373578
-
The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase
-
Godin CM, Ferguson SS. The angiotensin II type 1 receptor induces membrane blebbing by coupling to Rho A, Rho kinase, and myosin light chain kinase. Mol Pharmacol. 2010;77:903-911.
-
(2010)
Mol Pharmacol
, vol.77
, pp. 903-911
-
-
Godin, C.M.1
Ferguson, S.S.2
-
108
-
-
84892617010
-
Beta-arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration
-
Simard E, Kovacs JJ, Miller WE, et al. Beta-arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration. PLoS One. 2013;8:e80532.
-
(2013)
PLoS One
, vol.8
, pp. e80532
-
-
Simard, E.1
Kovacs, J.J.2
Miller, W.E.3
-
109
-
-
77951992340
-
Beta-arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2
-
Zoudilova M, Min J, Richards HL, et al. Beta-arrestins scaffold cofilin with chronophin to direct localized actin filament severing and membrane protrusions downstream of protease-activated receptor-2. J Biol Chem. 2010;285:14318-14329.
-
(2010)
J Biol Chem
, vol.285
, pp. 14318-14329
-
-
Zoudilova, M.1
Min, J.2
Richards, H.L.3
-
110
-
-
84888439320
-
Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and betaarrestin 1 pathway
-
Mittal N, Roberts K, Pal K, et al. Select G-protein-coupled receptors modulate agonist-induced signaling via a ROCK, LIMK, and betaarrestin 1 pathway. Cell Rep. 2013;5:1010-1021.
-
(2013)
Cell Rep
, vol.5
, pp. 1010-1021
-
-
Mittal, N.1
Roberts, K.2
Pal, K.3
-
111
-
-
84976904251
-
Endothelin A receptor drives invadopodia function and cell motility through the betaarrestin/ PDZ-RhoGEF pathway in ovarian carcinoma
-
Semprucci E, Tocci P, Cianfrocca R, et al. Endothelin A receptor drives invadopodia function and cell motility through the betaarrestin/ PDZ-RhoGEF pathway in ovarian carcinoma. Oncogene. 2016;35:3432-3442.
-
(2016)
Oncogene
, vol.35
, pp. 3432-3442
-
-
Semprucci, E.1
Tocci, P.2
Cianfrocca, R.3
-
112
-
-
84861986053
-
Wnt/beta-catenin signaling and disease
-
Clevers H, Nusse R. Wnt/beta-catenin signaling and disease. Cell. 2012; 149:1192-1205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
113
-
-
84959515677
-
Wnt signaling pathway in cardiac fibrosis: New insights and directions
-
Tao H, Yang JJ, Shi KH, et al. Wnt signaling pathway in cardiac fibrosis: new insights and directions. Metabolism. 2016;65:30-40.
-
(2016)
Metabolism
, vol.65
, pp. 30-40
-
-
Tao, H.1
Yang, J.J.2
Shi, K.H.3
-
114
-
-
77949411833
-
Beta-arrestins-scaffolds and signalling elements essential for WNT/Frizzled signalling pathways?
-
Schulte G, Schambony A, Bryja V. Beta-arrestins-scaffolds and signalling elements essential for WNT/Frizzled signalling pathways? Br J Pharmacol. 2010;159:1051-1058.
-
(2010)
Br J Pharmacol
, vol.159
, pp. 1051-1058
-
-
Schulte, G.1
Schambony, A.2
Bryja, V.3
-
115
-
-
0041470133
-
Dishevelled 2 recruits betaarrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
-
Chen W, ten Berge D, Brown J, et al. Dishevelled 2 recruits betaarrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science. 2003;301:1391-1394.
-
(2003)
Science
, vol.301
, pp. 1391-1394
-
-
Chen, W.1
Ten Berge, D.2
Brown, J.3
-
116
-
-
84891959525
-
Beta-arrestin promotes Wntinduced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein
-
Kriz V, Pospichalova V, Masek J, et al. Beta-arrestin promotes Wntinduced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. J Biol Chem. 2014;289:1128-1141.
-
(2014)
J Biol Chem
, vol.289
, pp. 1128-1141
-
-
Kriz, V.1
Pospichalova, V.2
Masek, J.3
-
117
-
-
34248995559
-
Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements
-
Kim GH, Han JK. Essential role for beta-arrestin 2 in the regulation of Xenopus convergent extension movements. EMBO J. 2007;26:2513-2526.
-
(2007)
EMBO J
, vol.26
, pp. 2513-2526
-
-
Kim, G.H.1
Han, J.K.2
-
118
-
-
84923764475
-
Distinct functionality of dishevelled isoforms on Ca2+/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation
-
Gentzel M, Schille C, Rauschenberger V, et al. Distinct functionality of dishevelled isoforms on Ca2+/calmodulin-dependent protein kinase 2 (CamKII) in Xenopus gastrulation. Mol Biol Cell. 2015;26:966-977.
-
(2015)
Mol Biol Cell
, vol.26
, pp. 966-977
-
-
Gentzel, M.1
Schille, C.2
Rauschenberger, V.3
-
119
-
-
84900297244
-
Beta-arrestin interacts with the beta/ gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2 +) pathway in xenopus gastrulation
-
Seitz K, Dursch V, Harnos J, et al. Beta-arrestin interacts with the beta/ gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2 +) pathway in xenopus gastrulation. PLoS One. 2014;9:e87132.
-
(2014)
PLoS One
, vol.9
, pp. e87132
-
-
Seitz, K.1
Dursch, V.2
Harnos, J.3
-
120
-
-
84055182505
-
Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through beta-arrestin and dishevelled-2 scaffolds
-
Soh UJ, Trejo J. Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through beta-arrestin and dishevelled-2 scaffolds. Proc Natl Acad Sci U S A. 2011;108:E1372-E1380.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. E1372-E1380
-
-
Soh, U.J.1
Trejo, J.2
-
121
-
-
84871584695
-
Biased agonism of proteaseactivated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46
-
Mosnier LO, Sinha RK, Burnier L, et al. Biased agonism of proteaseactivated receptor 1 by activated protein C caused by noncanonical cleavage at Arg46. Blood. 2012;120:5237-5246.
-
(2012)
Blood
, vol.120
, pp. 5237-5246
-
-
Mosnier, L.O.1
Sinha, R.K.2
Burnier, L.3
-
122
-
-
21244502159
-
Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling
-
Riewald M, Ruf W. Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling. J Biol Chem. 2005;280:19808-19814.
-
(2005)
J Biol Chem
, vol.280
, pp. 19808-19814
-
-
Riewald, M.1
Ruf, W.2
-
123
-
-
0032975515
-
Pro-and anti-inflammatory actions of thrombin: A distinct role for proteinase-activated receptor-1 (PAR1)
-
Vergnolle N, Hollenberg MD, Wallace JL. Pro-and anti-inflammatory actions of thrombin: a distinct role for proteinase-activated receptor-1 (PAR1). Br J Pharmacol. 1999;126:1262-1268.
-
(1999)
Br J Pharmacol
, vol.126
, pp. 1262-1268
-
-
Vergnolle, N.1
Hollenberg, M.D.2
Wallace, J.L.3
-
124
-
-
64849083719
-
Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1
-
Schuepbach RA, Feistritzer C, Fernandez JA, et al. Protection of vascular barrier integrity by activated protein C in murine models depends on protease-activated receptor-1. Thromb Haemost. 2009;101:724-733.
-
(2009)
Thromb Haemost
, vol.101
, pp. 724-733
-
-
Schuepbach, R.A.1
Feistritzer, C.2
Fernandez, J.A.3
-
125
-
-
85025105846
-
Occupancy of human EPCR by protein C induces beta-arrestin-2 biased PAR1 signaling by both APC and thrombin
-
Roy RV, Ardeshirylajimi A, Dinarvand P, et al. Occupancy of human EPCR by protein C induces beta-arrestin-2 biased PAR1 signaling by both APC and thrombin. Blood. 2016;128:1884-1893.
-
(2016)
Blood
, vol.128
, pp. 1884-1893
-
-
Roy, R.V.1
Ardeshirylajimi, A.2
Dinarvand, P.3
-
126
-
-
84886100276
-
Beta-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced beta-catenin signaling
-
Rosano L, Cianfrocca R, Tocci P, et al. Beta-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced beta-catenin signaling. Oncogene. 2013;32:5066-5077.
-
(2013)
Oncogene
, vol.32
, pp. 5066-5077
-
-
Rosano, L.1
Cianfrocca, R.2
Tocci, P.3
-
127
-
-
84918530212
-
Endothelin A receptor/betaarrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy
-
Rosano L, Cianfrocca R, Tocci P, et al. Endothelin A receptor/betaarrestin signaling to the Wnt pathway renders ovarian cancer cells resistant to chemotherapy. Cancer Res. 2014;74:7453-7464.
-
(2014)
Cancer Res
, vol.74
, pp. 7453-7464
-
-
Rosano, L.1
Cianfrocca, R.2
Tocci, P.3
-
129
-
-
11144285406
-
Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway
-
Wilbanks AM, Fralish GB, Kirby ML, et al. Beta-arrestin 2 regulates zebrafish development through the hedgehog signaling pathway. Science. 2004;306:2264-2267.
-
(2004)
Science
, vol.306
, pp. 2264-2267
-
-
Wilbanks, A.M.1
Fralish, G.B.2
Kirby, M.L.3
-
131
-
-
11144256194
-
Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2
-
Chen W, Ren XR, Nelson CD, et al. Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2. Science. 2004; 306:2257-2260.
-
(2004)
Science
, vol.306
, pp. 2257-2260
-
-
Chen, W.1
Ren, X.R.2
Nelson, C.D.3
-
132
-
-
46449127054
-
Beta-arrestin-mediated localization of smoothened to the primary cilium
-
Kovacs JJ, Whalen EJ, Liu R, et al. Beta-arrestin-mediated localization of smoothened to the primary cilium. Science. 2008;320:1777-1781.
-
(2008)
Science
, vol.320
, pp. 1777-1781
-
-
Kovacs, J.J.1
Whalen, E.J.2
Liu, R.3
-
133
-
-
84856098531
-
Oxysterols are allosteric activators of the oncoprotein Smoothened
-
Nachtergaele S, Mydock LK, Krishnan K, et al. Oxysterols are allosteric activators of the oncoprotein Smoothened. Nat Chem Biol. 2012; 8:211-220.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 211-220
-
-
Nachtergaele, S.1
Mydock, L.K.2
Krishnan, K.3
-
135
-
-
84883487161
-
Interaction of smoothened with integrinlinked kinase in primary cilia mediates Hedgehog signalling
-
Barakat B, Yu L, Lo C, et al. Interaction of smoothened with integrinlinked kinase in primary cilia mediates Hedgehog signalling. EMBO Rep. 2013;14:837-844.
-
(2013)
EMBO Rep
, vol.14
, pp. 837-844
-
-
Barakat, B.1
Yu, L.2
Lo, C.3
-
136
-
-
84978103999
-
Smoothened determines betaarrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium
-
Pal K, Hwang SH, Somatilaka B, et al. Smoothened determines betaarrestin-mediated removal of the G protein-coupled receptor Gpr161 from the primary cilium. J Cell Biol. 2016;212:861-875.
-
(2016)
J Cell Biol
, vol.212
, pp. 861-875
-
-
Pal, K.1
Hwang, S.H.2
Somatilaka, B.3
-
137
-
-
84872508509
-
The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling
-
Mukhopadhyay S, Wen X, Ratti N, et al. The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell. 2013;152:210-223.
-
(2013)
Cell
, vol.152
, pp. 210-223
-
-
Mukhopadhyay, S.1
Wen, X.2
Ratti, N.3
-
138
-
-
80052606605
-
Molecular basis of lysophosphatidic acid-induced NFkappaB activation
-
Sun W, Yang J. Molecular basis of lysophosphatidic acid-induced NFkappaB activation. Cell Signal. 2010;22:1799-1803.
-
(2010)
Cell Signal
, vol.22
, pp. 1799-1803
-
-
Sun, W.1
Yang, J.2
-
139
-
-
31344463886
-
Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling
-
Wang Y, Tang Y, Teng L, et al. Association of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signaling. Nat Immunol. 2006;7:139-147.
-
(2006)
Nat Immunol
, vol.7
, pp. 139-147
-
-
Wang, Y.1
Tang, Y.2
Teng, L.3
-
140
-
-
2342510314
-
Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways
-
Gao H, Sun Y, Wu Y, et al. Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways. Mol Cell. 2004;14:303-317.
-
(2004)
Mol Cell
, vol.14
, pp. 303-317
-
-
Gao, H.1
Sun, Y.2
Wu, Y.3
-
141
-
-
2942554958
-
Beta-arrestin inhibits NFkappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha
-
Witherow DS, Garrison TR, Miller WE, et al. Beta-arrestin inhibits NFkappaB activity by means of its interaction with the NF-kappaB inhibitor IkappaBalpha. Proc Natl Acad Sci U S A. 2004;101:8603-8607.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 8603-8607
-
-
Witherow, D.S.1
Garrison, T.R.2
Miller, W.E.3
-
142
-
-
48049101191
-
Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration
-
Kim J, Zhang L, Peppel K, et al. Beta-arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration. Circ Res. 2008;103:70-79.
-
(2008)
Circ Res
, vol.103
, pp. 70-79
-
-
Kim, J.1
Zhang, L.2
Peppel, K.3
-
143
-
-
84894528689
-
Beta-arrestin 1 is required for endothelin-1-induced NF-kappaB activation in ovarian cancer cells
-
Cianfrocca R, Tocci P, Semprucci E, et al. Beta-arrestin 1 is required for endothelin-1-induced NF-kappaB activation in ovarian cancer cells. Life Sci. 2014;118:179-184.
-
(2014)
Life Sci
, vol.118
, pp. 179-184
-
-
Cianfrocca, R.1
Tocci, P.2
Semprucci, E.3
-
144
-
-
77951872871
-
Beta-arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation
-
Mangmool S, Shukla AK, Rockman HA. Beta-arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation. J Cell Biol. 2010;189:573-587.
-
(2010)
J Cell Biol
, vol.189
, pp. 573-587
-
-
Mangmool, S.1
Shukla, A.K.2
Rockman, H.A.3
-
145
-
-
70349613570
-
Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction
-
Yoo B, Lemaire A, Mangmool S, et al. Beta1-adrenergic receptors stimulate cardiac contractility and CaMKII activation in vivo and enhance cardiac dysfunction following myocardial infarction. Am J Physiol Heart Circ Physiol. 2009;297:H1377-H1386.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
, pp. H1377-H1386
-
-
Yoo, B.1
Lemaire, A.2
Mangmool, S.3
-
146
-
-
84873601412
-
Specific interactions between Epac1, beta-arrestin2 and PDE4D5 regulate betaadrenergic receptor subtype differential effects on cardiac hypertrophic signaling
-
Berthouze-Duquesnes M, Lucas A, Sauliere A, et al. Specific interactions between Epac1, beta-arrestin2 and PDE4D5 regulate betaadrenergic receptor subtype differential effects on cardiac hypertrophic signaling. Cell Signal. 2013;25:970-980.
-
(2013)
Cell Signal
, vol.25
, pp. 970-980
-
-
Berthouze-Duquesnes, M.1
Lucas, A.2
Sauliere, A.3
-
148
-
-
84981517053
-
GPCR-g protein-betaarrestin super-complex mediates sustained G protein signaling
-
Thomsen AR, Plouffe B, Cahill TJ III, et al. GPCR-g protein-betaarrestin super-complex mediates sustained G protein signaling. Cell. 2016;166:907-919.
-
(2016)
Cell
, vol.166
, pp. 907-919
-
-
Thomsen, A.R.1
Plouffe, B.2
Cahill, T.J.3
-
150
-
-
84884761170
-
Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin
-
Feinstein TN, Yui N, Webber MJ, et al. Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin. J Biol Chem. 2013;288:27849-27860.
-
(2013)
J Biol Chem
, vol.288
, pp. 27849-27860
-
-
Feinstein, T.N.1
Yui, N.2
Webber, M.J.3
-
151
-
-
84875604499
-
Conformational biosensors reveal GPCR signalling from endosomes
-
Irannejad R, Tomshine JC, Tomshine JR, et al. Conformational biosensors reveal GPCR signalling from endosomes. Nature. 2013;495:534-538.
-
(2013)
Nature
, vol.495
, pp. 534-538
-
-
Irannejad, R.1
Tomshine, J.C.2
Tomshine, J.R.3
-
152
-
-
84872847980
-
Noncanonical GPCR signaling arising from a PTH receptor-arrestin-gbetagamma complex
-
Wehbi VL, Stevenson HP, Feinstein TN, et al. Noncanonical GPCR signaling arising from a PTH receptor-arrestin-gbetagamma complex. Proc Natl Acad Sci U S A. 2013;110:1530-1535.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 1530-1535
-
-
Wehbi, V.L.1
Stevenson, H.P.2
Feinstein, T.N.3
-
153
-
-
65949105042
-
Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors
-
Mullershausen F, Zecri F, Cetin C, et al. Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors. Nat Chem Biol. 2009;5:428-434.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 428-434
-
-
Mullershausen, F.1
Zecri, F.2
Cetin, C.3
-
155
-
-
70349309325
-
Sustained cyclic AMP production by parathyroid hormone receptor endocytosis
-
Ferrandon S, Feinstein TN, Castro M, et al. Sustained cyclic AMP production by parathyroid hormone receptor endocytosis. Nat Chem Biol. 2009;5:734-742.
-
(2009)
Nat Chem Biol
, vol.5
, pp. 734-742
-
-
Ferrandon, S.1
Feinstein, T.N.2
Castro, M.3
-
156
-
-
84879088103
-
True arrestins and arrestin-fold proteins: A structurebased appraisal
-
Aubry L, Klein G. True arrestins and arrestin-fold proteins: a structurebased appraisal. Prog Mol Biol Transl Sci. 2013;118:21-56.
-
(2013)
Prog Mol Biol Transl Sci
, vol.118
, pp. 21-56
-
-
Aubry, L.1
Klein, G.2
-
157
-
-
84906232914
-
Visualization of arrestin recruitment by a G-protein-coupled receptor
-
Shukla AK, Westfield GH, Xiao K, et al. Visualization of arrestin recruitment by a G-protein-coupled receptor. Nature. 2014;512:218-222.
-
(2014)
Nature
, vol.512
, pp. 218-222
-
-
Shukla, A.K.1
Westfield, G.H.2
Xiao, K.3
-
158
-
-
84994890792
-
Functional competence of a partially engaged GPCR-beta-arrestin complex
-
Kumari P, Srivastava A, Banerjee R, et al. Functional competence of a partially engaged GPCR-beta-arrestin complex. Nat Commun. 2016;7: 13416.
-
(2016)
Nat Commun
, vol.7
, pp. 13416
-
-
Kumari, P.1
Srivastava, A.2
Banerjee, R.3
-
159
-
-
8144222927
-
Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes
-
Terrillon S, Bouvier M. Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes. EMBO J. 2004;23: 3950-3961.
-
(2004)
EMBO J
, vol.23
, pp. 3950-3961
-
-
Terrillon, S.1
Bouvier, M.2
-
160
-
-
84964692098
-
Regulation of chronic inflammatory and immune processes by extracellular vesicles
-
Robbins PD, Dorronsoro A, Booker CN. Regulation of chronic inflammatory and immune processes by extracellular vesicles. J Clin Invest. 2016;126:1173-1180.
-
(2016)
J Clin Invest
, vol.126
, pp. 1173-1180
-
-
Robbins, P.D.1
Dorronsoro, A.2
Booker, C.N.3
-
161
-
-
84935449205
-
Circulating exosomes induced by cardiac pressure overload contain functional angiotensin II type 1 receptors
-
Pironti G, Strachan RT, Abraham D, et al. Circulating exosomes induced by cardiac pressure overload contain functional angiotensin II type 1 receptors. Circulation. 2015;131:2120-2130.
-
(2015)
Circulation
, vol.131
, pp. 2120-2130
-
-
Pironti, G.1
Strachan, R.T.2
Abraham, D.3
-
162
-
-
0141703263
-
Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
-
Wei H, Ahn S, Shenoy SK, et al. Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proc Natl Acad Sci U S A. 2003;100: 10782-10787.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 10782-10787
-
-
Wei, H.1
Ahn, S.2
Shenoy, S.K.3
-
163
-
-
77954693401
-
Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists
-
Christensen GL, Kelstrup CD, Lyngso C, et al. Quantitative phosphoproteomics dissection of seven-transmembrane receptor signaling using full and biased agonists. Mol Cell Proteomics. 2010;9:1540-1553.
-
(2010)
Mol Cell Proteomics
, vol.9
, pp. 1540-1553
-
-
Christensen, G.L.1
Kelstrup, C.D.2
Lyngso, C.3
-
164
-
-
77956998735
-
Global phosphorylation analysis of betaarrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)
-
Xiao K, Sun J, Kim J, et al. Global phosphorylation analysis of betaarrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci U S A. 2010;107:15299-15304.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 15299-15304
-
-
Xiao, K.1
Sun, J.2
Kim, J.3
-
165
-
-
44849117014
-
Beta-arrestin-mediated signaling regulates protein synthesis
-
DeWire SM, Kim J, Whalen EJ, et al. Beta-arrestin-mediated signaling regulates protein synthesis. J Biol Chem. 2008;283:10611-10620.
-
(2008)
J Biol Chem
, vol.283
, pp. 10611-10620
-
-
DeWire, S.M.1
Kim, J.2
Whalen, E.J.3
-
166
-
-
65249162262
-
An adrenal beta-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo
-
Lymperopoulos A, Rengo G, Zincarelli C, et al. An adrenal beta-arrestin 1-mediated signaling pathway underlies angiotensin II-induced aldosterone production in vitro and in vivo. Proc Natl Acad Sci U S A. 2009; 106:5825-5830.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5825-5830
-
-
Lymperopoulos, A.1
Rengo, G.2
Zincarelli, C.3
-
167
-
-
84892921129
-
Negative impact of betaarrestin-1 on post-myocardial infarction heart failure via cardiac andadrenal-dependent neurohormonal mechanisms
-
Bathgate-Siryk A, Dabul S, Pandya K, et al. Negative impact of betaarrestin-1 on post-myocardial infarction heart failure via cardiac andadrenal-dependent neurohormonal mechanisms. Hypertension. 2014;63: 404-412.
-
(2014)
Hypertension
, vol.63
, pp. 404-412
-
-
Bathgate-Siryk, A.1
Dabul, S.2
Pandya, K.3
-
168
-
-
85020900361
-
Structure-activity relationship study of angiotensin II analogs in terms of beta-arrestin-dependent signaling to aldosterone production
-
Valero TR, Sturchler E, Jafferjee M, et al. Structure-activity relationship study of angiotensin II analogs in terms of beta-arrestin-dependent signaling to aldosterone production. Pharmacol Res Perspect. 2016;4: e00226.
-
(2016)
Pharmacol Res Perspect
, vol.4
, pp. e00226
-
-
Valero, T.R.1
Sturchler, E.2
Jafferjee, M.3
-
169
-
-
79960382104
-
Biased ligands for better cardiovascular drugs: Dissecting G-protein-coupled receptor pharmacology
-
DeWire SM, Violin JD. Biased ligands for better cardiovascular drugs: dissecting G-protein-coupled receptor pharmacology. Circ Res. 2011; 109:205-216.
-
(2011)
Circ Res
, vol.109
, pp. 205-216
-
-
DeWire, S.M.1
Violin, J.D.2
-
170
-
-
78649609643
-
Selectively engaging betaarrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance
-
Violin JD, DeWire SM, Yamashita D, et al. Selectively engaging betaarrestins at the angiotensin II type 1 receptor reduces blood pressure and increases cardiac performance. J Pharmacol Exp Ther. 2010;335:572-579.
-
(2010)
J Pharmacol Exp Ther
, vol.335
, pp. 572-579
-
-
Violin, J.D.1
DeWire, S.M.2
Yamashita, D.3
-
171
-
-
84994881308
-
Cardioprotective angiotensin-(1-7) peptide acts as a natural-biased ligand at the angiotensin II type 1 receptor
-
Galandrin S, Denis C, Boularan C, et al. Cardioprotective angiotensin-(1-7) peptide acts as a natural-biased ligand at the angiotensin II type 1 receptor. Hypertension. 2016;68:1365-1374.
-
(2016)
Hypertension
, vol.68
, pp. 1365-1374
-
-
Galandrin, S.1
Denis, C.2
Boularan, C.3
-
172
-
-
0037050009
-
Seven-transmembrane-spanning receptors and heart function
-
Rockman HA, Koch WJ, Lefkowitz RJ. Seven-transmembrane-spanning receptors and heart function. Nature. 2002;415:206-212.
-
(2002)
Nature
, vol.415
, pp. 206-212
-
-
Rockman, H.A.1
Koch, W.J.2
Lefkowitz, R.J.3
-
173
-
-
0024994781
-
Beta-adrenergic pathways in nonfailing and failing human ventricular myocardium
-
Bristow MR, Hershberger RE, Port JD, et al. Beta-adrenergic pathways in nonfailing and failing human ventricular myocardium. Circulation. 1990;82:I12-I25.
-
(1990)
Circulation
, vol.82
, pp. I12-I25
-
-
Bristow, M.R.1
Hershberger, R.E.2
Port, J.D.3
-
174
-
-
0034976707
-
Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure
-
Port JD, Bristow MR. Altered beta-adrenergic receptor gene regulation and signaling in chronic heart failure. J Mol Cell Cardiol. 2001;33:887-905.
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 887-905
-
-
Port, J.D.1
Bristow, M.R.2
-
175
-
-
84873403704
-
Cardiomyocyte life-death decisions in response to chronic beta-adrenergic signaling
-
Whelan RS, Konstantinidis K, Xiao RP, et al. Cardiomyocyte life-death decisions in response to chronic beta-adrenergic signaling. Circ Res. 2013;112:408-410.
-
(2013)
Circ Res
, vol.112
, pp. 408-410
-
-
Whelan, R.S.1
Konstantinidis, K.2
Xiao, R.P.3
-
176
-
-
84890957716
-
Beta-arrestins in cardiac G proteincoupled receptor signaling and function: Partners in crime or good cop, bad cop?
-
Lymperopoulos A, Negussie S. Beta-arrestins in cardiac G proteincoupled receptor signaling and function: partners in crime or good cop, bad cop? Int J Mol Sci. 2013;14:24726-24741.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 24726-24741
-
-
Lymperopoulos, A.1
Negussie, S.2
-
178
-
-
8244219693
-
Pharmacology of carvedilol: Rationale for use in hypertension, coronary artery disease, and congestive heart failure
-
Ruffolo RR Jr, Feuerstein GZ. Pharmacology of carvedilol: rationale for use in hypertension, coronary artery disease, and congestive heart failure. Cardiovasc Drugs Ther. 1997;11(suppl 1):247-256.
-
(1997)
Cardiovasc Drugs Ther
, vol.11
, pp. 247-256
-
-
Ruffolo, R.R.1
Feuerstein, G.Z.2
-
179
-
-
36749094552
-
A unique mechanism of betablocker action: Carvedilol stimulates beta-arrestin signaling
-
Wisler JW, DeWire SM, Whalen EJ, et al. A unique mechanism of betablocker action: carvedilol stimulates beta-arrestin signaling. Proc Natl Acad Sci U S A. 2007;104:16657-16662.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 16657-16662
-
-
Wisler, J.W.1
DeWire, S.M.2
Whalen, E.J.3
-
180
-
-
33751162165
-
Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogenactivated protein kinase reveals the pluridimensionality of efficacy
-
Galandrin S, Bouvier M. Distinct signaling profiles of beta1 and beta2 adrenergic receptor ligands toward adenylyl cyclase and mitogenactivated protein kinase reveals the pluridimensionality of efficacy. Mol Pharmacol. 2006;70:1575-1584.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1575-1584
-
-
Galandrin, S.1
Bouvier, M.2
-
181
-
-
55749084393
-
Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation
-
Kim IM, Tilley DG, Chen J, et al. Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation. Proc Natl Acad Sci U S A. 2008;105:14555-14560.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14555-14560
-
-
Kim, I.M.1
Tilley, D.G.2
Chen, J.3
-
182
-
-
84895930317
-
Beta-arrestin1-biased beta1-adrenergic receptor signaling regulates microRNA processing
-
Kim IM, Wang Y, Park KM, et al. Beta-arrestin1-biased beta1-adrenergic receptor signaling regulates microRNA processing. Circ Res. 2014;114:833-844.
-
(2014)
Circ Res
, vol.114
, pp. 833-844
-
-
Kim, I.M.1
Wang, Y.2
Park, K.M.3
-
183
-
-
84989332560
-
Potential role of MicroRNAs in cardiovascular disease: Are they up to their hype?
-
Duggal B, Gupta MK, Naga Prasad SV. Potential role of MicroRNAs in cardiovascular disease: are they up to their hype? Curr Cardiol Rev. 2016;12:304-310.
-
(2016)
Curr Cardiol Rev
, vol.12
, pp. 304-310
-
-
Duggal, B.1
Gupta, M.K.2
Naga Prasad, S.V.3
-
184
-
-
70350463883
-
Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks
-
Naga Prasad SV, Duan ZH, Gupta MK, et al. Unique microRNA profile in end-stage heart failure indicates alterations in specific cardiovascular signaling networks. J Biol Chem. 2009;284:27487-27499.
-
(2009)
J Biol Chem
, vol.284
, pp. 27487-27499
-
-
Naga Prasad, S.V.1
Duan, Z.H.2
Gupta, M.K.3
-
185
-
-
84930331083
-
MicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death
-
Tang Y, Wang Y, Park KM, et al. MicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death. Cardiovasc Res. 2015;106:387-397.
-
(2015)
Cardiovasc Res
, vol.106
, pp. 387-397
-
-
Tang, Y.1
Wang, Y.2
Park, K.M.3
-
186
-
-
84969631872
-
MicroRNA-150 inhibits the activation of cardiac fibroblasts by regulating c-Myb
-
Deng P, Chen L, Liu Z, et al. MicroRNA-150 inhibits the activation of cardiac fibroblasts by regulating c-Myb. Cell Physiol Biochem. 2016; 38:2103-2122.
-
(2016)
Cell Physiol Biochem
, vol.38
, pp. 2103-2122
-
-
Deng, P.1
Chen, L.2
Liu, Z.3
-
187
-
-
85015203386
-
LncRNA MIAT enhances cardiac hypertrophy partly through sponging MIR-150
-
Zhu XH, Yuan YX, Rao SL, et al. LncRNA MIAT enhances cardiac hypertrophy partly through sponging miR-150. Eur Rev Med Pharmacol Sci. 2016;20:3653-3660.
-
(2016)
Eur Rev Med Pharmacol Sci
, vol.20
, pp. 3653-3660
-
-
Zhu, X.H.1
Yuan, Y.X.2
Rao, S.L.3
-
188
-
-
84924532623
-
MicroRNA-150 protects the heart from injury by inhibiting monocyte accumulation in a mouse model of acute myocardial infarction
-
Liu Z, Ye P, Wang S, et al. MicroRNA-150 protects the heart from injury by inhibiting monocyte accumulation in a mouse model of acute myocardial infarction. Circ Cardiovasc Genet. 2015;8:11-20.
-
(2015)
Circ Cardiovasc Genet
, vol.8
, pp. 11-20
-
-
Liu, Z.1
Ye, P.2
Wang, S.3
-
189
-
-
84939185722
-
MicroRNA-150 protects against pressure overload-induced cardiac hypertrophy
-
Liu W, Liu Y, Zhang Y, et al. MicroRNA-150 protects against pressure overload-induced cardiac hypertrophy. J Cell Biochem. 2015;116: 2166-2176.
-
(2015)
J Cell Biochem
, vol.116
, pp. 2166-2176
-
-
Liu, W.1
Liu, Y.2
Zhang, Y.3
-
190
-
-
84896709217
-
Relation of reduced expression of MIR-150 in platelets to atrial fibrillation in patients with chronic systolic heart failure
-
Goren Y, Meiri E, Hogan C, et al. Relation of reduced expression of MiR-150 in platelets to atrial fibrillation in patients with chronic systolic heart failure. Am J Cardiol. 2014;113:976-981.
-
(2014)
Am J Cardiol
, vol.113
, pp. 976-981
-
-
Goren, Y.1
Meiri, E.2
Hogan, C.3
-
191
-
-
84983628302
-
Carvedilol-responsive microRNAs, MIR-199a-3p and-214 protect cardiomyocytes from simulated ischemia-reperfusion injury
-
Park KM, Teoh JP, Wang Y, et al. Carvedilol-responsive microRNAs, miR-199a-3p and-214 protect cardiomyocytes from simulated ischemia-reperfusion injury. Am J Physiol Heart Circ Physiol. 2016; 311:H371-H383.
-
(2016)
Am J Physiol Heart Circ Physiol
, vol.311
, pp. H371-H383
-
-
Park, K.M.1
Teoh, J.P.2
Wang, Y.3
-
192
-
-
0242352636
-
Blocking receptors on the inside: Pepducinbased intervention of PAR signaling and thrombosis
-
Kuliopulos A, Covic L. Blocking receptors on the inside: pepducinbased intervention of PAR signaling and thrombosis. Life Sci. 2003; 74:255-262.
-
(2003)
Life Sci
, vol.74
, pp. 255-262
-
-
Kuliopulos, A.1
Covic, L.2
-
193
-
-
84859760355
-
Turning receptors on and off with intracellular pepducins: New insights into G-protein-coupled receptor drug development
-
O'Callaghan K, Kuliopulos A, Covic L. Turning receptors on and off with intracellular pepducins: new insights into G-protein-coupled receptor drug development. J Biol Chem. 2012;287:12787-12796.
-
(2012)
J Biol Chem
, vol.287
, pp. 12787-12796
-
-
O'Callaghan, K.1
Kuliopulos, A.2
Covic, L.3
-
194
-
-
84978128490
-
Beta-arrestin-biased signaling through the beta2-adrenergic receptor promotes cardiomyocyte contraction
-
Carr R III, Schilling J, Song J, et al. Beta-arrestin-biased signaling through the beta2-adrenergic receptor promotes cardiomyocyte contraction. Proc Natl Acad Sci U S A. 2016;113:E4107-E4116.
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E4107-E4116
-
-
Carr, R.1
Schilling, J.2
Song, J.3
-
195
-
-
81055145330
-
Discovery of beta-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy
-
Allen JA, Yost JM, Setola V, et al. Discovery of beta-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic efficacy. Proc Natl Acad Sci U S A. 2011;108:18488-18493.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 18488-18493
-
-
Allen, J.A.1
Yost, J.M.2
Setola, V.3
-
196
-
-
77949458560
-
Third generation antipsychotic drugs: Partial agonism or receptor functional selectivity?
-
Mailman RB, Murthy V. Third generation antipsychotic drugs: partial agonism or receptor functional selectivity? Curr Pharm Des. 2010;16: 488-501.
-
(2010)
Curr Pharm des
, vol.16
, pp. 488-501
-
-
Mailman, R.B.1
Murthy, V.2
-
197
-
-
73949084919
-
A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation
-
Gesty-Palmer D, Flannery P, Yuan L, et al. A beta-arrestin-biased agonist of the parathyroid hormone receptor (PTH1R) promotes bone formation independent of G protein activation. Sci Transl Med. 2009;1:1ra1.
-
(2009)
Sci Transl Med
, vol.1
, pp. 1ra1
-
-
Gesty-Palmer, D.1
Flannery, P.2
Yuan, L.3
-
198
-
-
84873042671
-
Beta-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo
-
Gesty-Palmer D, Yuan L, Martin B, et al. Beta-arrestin-selective G protein-coupled receptor agonists engender unique biological efficacy in vivo. Mol Endocrinol. 2013;27:296-314.
-
(2013)
Mol Endocrinol
, vol.27
, pp. 296-314
-
-
Gesty-Palmer, D.1
Yuan, L.2
Martin, B.3
-
199
-
-
15444378518
-
Beta-arrestin-and G protein receptor kinase-mediated calcium-sensing receptor desensitization
-
Pi M, Oakley RH, Gesty-Palmer D, et al. Beta-arrestin-and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Mol Endocrinol. 2005;19:1078-1087.
-
(2005)
Mol Endocrinol
, vol.19
, pp. 1078-1087
-
-
Pi, M.1
Oakley, R.H.2
Gesty-Palmer, D.3
-
200
-
-
80053927094
-
The antidepressant desipramine is an arrestin-biased ligand at the alpha(2A)-adrenergic receptor driving receptor down-regulation in vitro and in vivo
-
Cottingham C, Chen Y, Jiao K, et al. The antidepressant desipramine is an arrestin-biased ligand at the alpha(2A)-adrenergic receptor driving receptor down-regulation in vitro and in vivo. J Biol Chem. 2011;286: 36063-36075.
-
(2011)
J Biol Chem
, vol.286
, pp. 36063-36075
-
-
Cottingham, C.1
Chen, Y.2
Jiao, K.3
-
201
-
-
80051979129
-
Quantifying ligand bias at seven-transmembrane receptors
-
Rajagopal S, Ahn S, Rominger DH, et al. Quantifying ligand bias at seven-transmembrane receptors. Mol Pharmacol. 2011;80:367-377.
-
(2011)
Mol Pharmacol
, vol.80
, pp. 367-377
-
-
Rajagopal, S.1
Ahn, S.2
Rominger, D.H.3
-
202
-
-
84940742699
-
Identification of gene signatures regulated by carvedilol in mouse heart
-
Teoh JP, Park KM, Broskova Z, et al. Identification of gene signatures regulated by carvedilol in mouse heart. Physiol Genomics. 2015;47: 376-385.
-
(2015)
Physiol Genomics
, vol.47
, pp. 376-385
-
-
Teoh, J.P.1
Park, K.M.2
Broskova, Z.3
-
203
-
-
84882629555
-
The beta-blocker nebivolol Is a GRK/beta-arrestin biased agonist
-
Erickson CE, Gul R, Blessing CP, et al. The beta-blocker nebivolol Is a GRK/beta-arrestin biased agonist. PLoS One. 2013;8:e71980.
-
(2013)
PLoS One
, vol.8
, pp. e71980
-
-
Erickson, C.E.1
Gul, R.2
Blessing, C.P.3
-
204
-
-
84961172231
-
Discovery and characterization of biased allosteric agonists of the chemokine receptor CXCR3
-
Milanos L, Brox R, Frank T, et al. Discovery and characterization of biased allosteric agonists of the chemokine receptor CXCR3. J Med Chem. 2016;59:2222-2243.
-
(2016)
J Med Chem
, vol.59
, pp. 2222-2243
-
-
Milanos, L.1
Brox, R.2
Frank, T.3
-
205
-
-
84997796763
-
Identification of two distinct sites for antagonist and biased agonist binding to the human chemokine receptor CXCR3
-
Milanos L, Saleh N, Kling RC, et al. Identification of two distinct sites for antagonist and biased agonist binding to the human chemokine receptor CXCR3. Angew Chem Int Ed Engl. 2016;55:15277-15281.
-
(2016)
Angew Chem Int Ed Engl
, vol.55
, pp. 15277-15281
-
-
Milanos, L.1
Saleh, N.2
Kling, R.C.3
-
206
-
-
84939856434
-
Beta-arrestin recruitment and biased agonism at free fatty acid receptor 1
-
Mancini AD, Bertrand G, Vivot K, et al. Beta-arrestin recruitment and biased agonism at free fatty acid receptor 1. J Biol Chem. 2015;290: 21131-21140.
-
(2015)
J Biol Chem
, vol.290
, pp. 21131-21140
-
-
Mancini, A.D.1
Bertrand, G.2
Vivot, K.3
-
207
-
-
79953006585
-
Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits beta-arrestin without activating G proteins
-
Rosethorne EM, Charlton SJ. Agonist-biased signaling at the histamine H4 receptor: JNJ7777120 recruits beta-arrestin without activating G proteins. Mol Pharmacol. 2011;79:749-757.
-
(2011)
Mol Pharmacol
, vol.79
, pp. 749-757
-
-
Rosethorne, E.M.1
Charlton, S.J.2
-
208
-
-
84863928803
-
Ligand bias at metabotropic glutamate 1a receptors: Molecular determinants that distinguish beta-arrestin-mediated from G protein-mediated signaling
-
Emery AC, DiRaddo JO, Miller E, et al. Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish beta-arrestin-mediated from G protein-mediated signaling. Mol Pharmacol. 2012;82:291-301.
-
(2012)
Mol Pharmacol
, vol.82
, pp. 291-301
-
-
Emery, A.C.1
DiRaddo, J.O.2
Miller, E.3
-
209
-
-
84978652298
-
ML314: A biased neurotensin receptor ligand for nethamphetamine abuse
-
Barak LS, Bai Y, Peterson S, et al. ML314: a biased neurotensin receptor ligand for nethamphetamine abuse. ACS Chem Biol. 2016;11:1880-1890.
-
(2016)
ACS Chem Biol
, vol.11
, pp. 1880-1890
-
-
Barak, L.S.1
Bai, Y.2
Peterson, S.3
-
210
-
-
84884257510
-
Discovery of ML314, a brain penetrant non-peptidic beta-arrestin biased agonist of the neurotensin NTR1 receptor
-
Peddibhotla S, Hedrick MP, Hershberger P, et al. Discovery of ML314, a brain penetrant non-peptidic beta-arrestin biased agonist of the neurotensin NTR1 receptor. ACS Med Chem Lett. 2013;4:846-851.
-
(2013)
ACS Med Chem Lett
, vol.4
, pp. 846-851
-
-
Peddibhotla, S.1
Hedrick, M.P.2
Hershberger, P.3
-
211
-
-
84890635488
-
Identification of novel functionally selective kappa-opioid receptor scaffolds
-
White KL, Scopton AP, Rives ML, et al. Identification of novel functionally selective kappa-opioid receptor scaffolds. Mol Pharmacol. 2014;85:83-90.
-
(2014)
Mol Pharmacol
, vol.85
, pp. 83-90
-
-
White, K.L.1
Scopton, A.P.2
Rives, M.L.3
|