A stress response pathway regulates DNA damage through β2- adrenoreceptors and β-arrestin-1

Nature

Volumn 477, Issue 7364, 2011, Pages 349-353

  Hara, Makoto R ^a   Kovacs, Jeffrey J ^a   Whalen, Erin J ^a   Rajagopal, Sudarshan ^a   Strachan, Ryan T ^a   Grant, Wayne ^b   Towers, Aaron J ^a   Williams, Barbara ^a   Lam, Christopher M ^a   Xiao, Kunhong ^a   Shenoy, Sudha K ^a   Gregory, Simon G ^a   Ahn, Seungkirl ^a   Duckett, Derek R ^b   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN 1; CATECHOLAMINE; PROTEIN MDM2; PROTEIN P53;

AGING; BIOCHEMISTRY; CARDIOVASCULAR DISEASE; CATABOLISM; CYTOLOGY; DISEASE INCIDENCE; DNA; ENVIRONMENTAL STRESS; ENZYME ACTIVITY; EPIDEMIOLOGY; GENOME; HOMEOSTASIS; HOMINID; HORMONE; NERVOUS SYSTEM; NERVOUS SYSTEM DISORDER; PATERNAL EFFECT; PROTEIN; SYMPTOM; TUMOR;

ANIMAL EXPERIMENT; ARTICLE; DNA DAMAGE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROTEIN BINDING; STRESS; TESTIS; THYMUS;

ANIMALS; ARRESTINS; CATECHOLAMINES; CELL LINE; CELL NUCLEUS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DNA DAMAGE; FIBROBLASTS; HUMANS; MALE; MICE; MICE, INBRED C57BL; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MDM2; RECEPTORS, ADRENERGIC, BETA-2; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL; TESTIS; THYMUS GLAND; TUMOR SUPPRESSOR PROTEIN P53;

MUS;

EID: 80052832196     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10368     Document Type: Article

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