Carvedilol-responsive microRNAs, miR-199a-3p and -214 protect cardiomyocytes from simulated ischemia-reperfusion injury

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 311, Issue 2, 2016, Pages H371-H383

  Park, Kyoung Mi ^a   Teoh, Jian Peng ^a   Wang, Yongchao ^a   Broskova, Zuzana ^a   Bayoumi, Ahmed S ^a   Tang, Yaoliang ^a   Su, Huabo ^a   Weintraub, Neal L ^a   Kim, Il Man ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Apoptosis; Heart disease; MicroRNAs; arrestin biased adrenergic receptor signaling; blocker

Indexed keywords

BETA 1 ADRENERGIC RECEPTOR; BETA ARRESTIN 1; CARVEDILOL; MICRORNA; MICRORNA 199A 3P; MICRORNA 214; PROTEIN KINASE B; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CARBAZOLE DERIVATIVE; MIRN199 MICRORNA, MOUSE; MIRN199 MICRORNA, RAT; MIRN214 MICRORNA, MOUSE; MIRN214 MICRORNA,RAT; PROPANOLAMINE DERIVATIVE;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIAC MUSCLE CELL; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE OVEREXPRESSION; GENE SILENCING; HEART CELL CULTURE; HEART PROTECTION; MOUSE; MYOCARDIAL ISCHEMIA REPERFUSION INJURY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SIMULATION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL LINE; COMPUTER SIMULATION; DRUG EFFECTS; GENETICS; IMMUNOBLOTTING; IN VITRO STUDY; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TUNEL ASSAY;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; APOPTOSIS; CARBAZOLES; CELL LINE; CELLS, CULTURED; COMPUTER SIMULATION; IMMUNOBLOTTING; IN SITU NICK-END LABELING; IN VITRO TECHNIQUES; MICE; MICE, INBRED C57BL; MICRORNAS; MYOCYTES, CARDIAC; PROPANOLAMINES; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; UP-REGULATION;

EID: 84983628302     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00807.2015     Document Type: Article

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