Structure of active β-arrestin-1 bound to a G-protein-coupled receptor phosphopeptide

Nature

Volumn 497, Issue 7447, 2013, Pages 137-141

  Shukla, Arun K ^a   Manglik, Aashish ^b   Kruse, Andrew C ^b   Xiao, Kunhong ^a   Reis, Rosana I ^a   Tseng, Wei Chou ^a   Staus, Dean P ^a   Hilger, Daniel ^b   Uysal, Serdar ^c   Huang, Li Yin ^a   Paduch, Marcin ^c   Tripathi Shukla, Prachi ^a   Koide, Akiko ^c   Koide, Shohei ^c   Weis, William I ^b   Kossiakoff, Anthony A ^c   Kobilka, Brian K ^b   Lefkowitz, Robert J ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ARRESTIN 1; G PROTEIN COUPLED RECEPTOR; PHOSPHOPEPTIDE; VASOPRESSIN V2 RECEPTOR;

ANTIBODY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; MOLECULAR ANALYSIS; PEPTIDE; PROTEIN; ROTATION;

ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HINGE REGION; INTERNALIZATION; MOLECULAR RECOGNITION; MUTAGENESIS; NONHUMAN; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN CROSS LINKING; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; ARRESTINS; CRYSTALLOGRAPHY, X-RAY; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MODELS, MOLECULAR; PHOSPHOPEPTIDES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; RATS; RECEPTORS, VASOPRESSIN; ROTATION;

EID: 84877581626     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12120     Document Type: Article

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