Phospho-selective mechanisms of arrestin conformations and functions revealed by unnatural amino acid incorporation and 19 F-NMR

Nature Communications

Volumn 6, Issue , 2015, Pages

  Yang, Fan ^a,b   Yu, Xiao ^b   Liu, Chuan ^b   Qu, Chang Xiu ^b   Gong, Zheng ^b   Liu, Hong Da ^b   Li, Fa Hui ^a   Wang, Hong Mei ^b   He, Dong Fang ^b   Yi, Fan ^b   Song, Chen ^c   Tian, Chang Lin ^d   Xiao, Kun Hong ^e,f   Wang, Jiang Yun ^a   Sun, Jin Peng ^b  

^a INSTITUTE OF BIOPHYSICS   (China)

^b SHANDONG UNIVERSITY   (China)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^e UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^f DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BETA ARRESTIN 1; CLATHRIN; FLUORINE; G PROTEIN COUPLED RECEPTOR; PHOSPHATE; PHOSPHOPEPTIDE; SMALL INTERFERING RNA; 3,5-DIFLUOROTYROSINE; ADRBK1 PROTEIN, HUMAN; ARRB1 PROTEIN, HUMAN; BETA ARRESTIN; G PROTEIN COUPLED RECEPTOR KINASE; G PROTEIN COUPLED RECEPTOR KINASE 2; G-PROTEIN-COUPLED RECEPTOR KINASE 6; PHOSPHATE BINDING PROTEIN; PHOSPHOPROTEIN; RETINA S ANTIGEN; TYROSINE;

AMINO ACID; NUCLEAR MAGNETIC RESONANCE; PEPTIDE; PHOSPHATE; PROTEIN;

ARTICLE; BINDING SITE; FLUORINE NUCLEAR MAGNETIC RESONANCE; HEK293 CELL LINE; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN CONFORMATION; PROTEIN PHOSPHORYLATION; PROTEIN PURIFICATION; WESTERN BLOTTING; ANALOGS AND DERIVATIVES; ANIMAL; BOVINE; CONFOCAL MICROSCOPY; ESCHERICHIA COLI; FLUORINE MAGNETIC RESONANCE IMAGING; GENETICS; METABOLISM; MUTATION; NUCLEAR MAGNETIC RESONANCE; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY;

ANIMALS; ARRESTINS; BETA-ARRESTIN 1; BETA-ARRESTINS; BINDING SITES; BLOTTING, WESTERN; CATTLE; CLATHRIN; ESCHERICHIA COLI; FLUORINE; FLUORINE-19 MAGNETIC RESONANCE IMAGING; G-PROTEIN-COUPLED RECEPTOR KINASE 2; G-PROTEIN-COUPLED RECEPTOR KINASES; HEK293 CELLS; HUMANS; MICROSCOPY, CONFOCAL; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHOSPHATE-BINDING PROTEINS; PHOSPHOPROTEINS; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; TYROSINE;

EID: 84941048021     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms9202     Document Type: Article

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