The role of phosphorylation in D1 dopamine receptor desensitization: Evidence for a novel mechanism of arrestin association

Journal of Biological Chemistry

Volumn 279, Issue 9, 2004, Pages 7999-8010

  Kim, Ok Jin ^a   Gardner, Benjamin R ^a,c   Williams, Daniel B ^a,d   Marinec, Paul S ^a   Cabrera, David M ^a   Peters, Jennifer D ^a,e   Mak, Chun C ^a   Kim, Kyeong Man ^b   Sibley, David R ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b Chonnam National University   (South Korea)

^c PFIZER GLOBAL RESEARCH AND DEVELOPMENT   (United Kingdom)

^d NEW MEXICO HIGHLANDS UNIVERSITY   (United States)

^e PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BIOASSAY; MICROSCOPIC EXAMINATION; MUTAGENESIS; PROTEINS;

DOPAMINE; PHOSPHORYLATION;

BIOCHEMISTRY;

DOPAMINE 1 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; PROTEIN KINASE C; RETINA S ANTIGEN; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; CYCLIC AMP; PHOTOPROTEIN; RECOMBINANT PROTEIN; TRITIUM;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CONFOCAL MICROSCOPY; DESENSITIZATION; DOPAMINE METABOLISM; DRUG RECEPTOR BINDING; ENDOCYTOSIS; ENZYME PHOSPHORYLATION; GENE MUTATION; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; RECEPTOR OCCUPANCY; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; BIOSYNTHESIS; BIOTINYLATION; CELL LINE; CHEMISTRY; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; PHOSPHORYLATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CONFORMATION; RADIOASSAY; RAT; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; TRANSPORT AT THE CELLULAR LEVEL;

(R)-2,3,4,5-TETRAHYDRO-8-CHLORO-3-METHYL-5-PHENYL-1H-3-BENZAZEPIN-7-OL; AMINO ACID SEQUENCE; ANIMALS; ARRESTIN; BINDING SITES; BIOLOGICAL TRANSPORT; BIOTINYLATION; CELL LINE; CYCLIC AMP; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHOSPHORYLATION; PROTEIN CONFORMATION; RADIOLIGAND ASSAY; RATS; RECEPTORS, DOPAMINE D1; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRITIUM;

EID: 1542349921     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M308281200     Document Type: Article

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