β-arrestin recruitment and biased agonism at free fatty acid receptor 1

Journal of Biological Chemistry

Volumn 290, Issue 34, 2015, Pages 21131-21140

  Mancini, Arturo D ^a   Bertrand, Gyslaine ^b   Vivot, Kevin ^a   Carpentier, Éric ^c   Tremblay, Caroline ^a   Ghislain, Julien ^a   Bouvier, Michel ^c   Poitout, Vincent ^a,c  

^a CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIV MONTPELLIER   (France)

^c UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BIOLOGICAL MEMBRANES; BIOSENSORS; CELL CULTURE; CELLS; CYTOLOGY; ENERGY TRANSFER; FATTY ACIDS; INSULIN; LIGANDS; PHYSIOLOGY; PROTEINS; SIGNAL TRANSDUCTION; SIGNALING;

BIOLUMINESCENCE RESONANCE ENERGY TRANSFER; FUNCTIONAL VALIDATION; HETEROTRIMERIC G PROTEINS; INSULIN SECRETING CELLS; INSULINOTROPIC ACTIVITY; PANCREATIC BETA CELLS; PHARMACOLOGICAL BLOCKADE; TRANS-MEMBRANE DOMAINS;

CELL SIGNALING;

BETA ARRESTIN; BETA ARRESTIN 1; BETA ARRESTIN 2; G PROTEIN COUPLED RECEPTOR 40; BENZOFURAN DERIVATIVE; G PROTEIN COUPLED RECEPTOR; G-PROTEIN-COUPLED RECEPTOR 40, RAT; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INSULIN; OLEIC ACID; PALMITIC ACID; RETINA S ANTIGEN; SMALL INTERFERING RNA; SULFONE; TAK-875;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; INSULIN RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RECEPTOR BINDING; SIGNAL TRANSDUCTION; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DRUG EFFECTS; ELECTRON SPIN RESONANCE; GENE EXPRESSION REGULATION; GENETIC PROCEDURES; GENETICS; HEK293 CELL LINE; HUMAN; KINETICS; METABOLISM; PANCREAS ISLET BETA CELL; RAT; SECRETION (PROCESS); TISSUE CULTURE TECHNIQUE; TUMOR CELL LINE;

ANIMALS; ARRESTINS; BENZOFURANS; BIOSENSING TECHNIQUES; CELL LINE, TUMOR; ELECTRON SPIN RESONANCE SPECTROSCOPY; GENE EXPRESSION REGULATION; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HUMANS; INSULIN; INSULIN-SECRETING CELLS; KINETICS; MICE; OLEIC ACID; PALMITIC ACID; RATS; RECEPTORS, G-PROTEIN-COUPLED; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SULFONES; TISSUE CULTURE TECHNIQUES;

EID: 84939856434     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.644450     Document Type: Article

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