Activated protein C promotes protease-activated receptor-1 cytoprotective signaling through β-arrestin and dishevelled-2 scaffolds

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 50, 2011, Pages

  Soh, Unice J K ^a   Trejo, JoAnn ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biased agonism; Endothelial dysfunction; Inflammation; Sepsis

Indexed keywords

ACTIVATED PROTEIN C; BETA ARRESTIN; CAVEOLIN 1; DISHEVELLED 2; PROTEASE ACTIVATED PROTEIN C; PROTEINASE ACTIVATED RECEPTOR 1; RAC1 PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL ACTIVATION; CELL PROTECTION; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEPLETION; PROTEIN EXPRESSION; RNA INTERFERENCE; UMBILICAL VEIN ENDOTHELIAL CELL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ARRESTINS; CAVEOLIN 1; CYTOPROTECTION; ENDOTHELIAL CELLS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; MEMBRANE MICRODOMAINS; PHOSPHOPROTEINS; POLYMERIZATION; PROTEIN BINDING; PROTEIN C; PROTEIN TRANSPORT; RAC1 GTP-BINDING PROTEIN; RECEPTOR, PAR-1; SIGNAL TRANSDUCTION;

EID: 84055182505     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1112482108     Document Type: Article

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