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Volumn 65, Issue 2, 2016, Pages 30-40

Wnt signaling pathway in cardiac fibrosis: New insights and directions

Author keywords

Cardiac fibroblast; Cardiac fibrosis; Proliferation; Wnt; Catenin

Indexed keywords

BETA CATENIN; WNT PROTEIN; CCN PROTEIN; CTNNB1 PROTEIN, HUMAN; FRZB PROTEIN; GLYCOPROTEIN; ONCOPROTEIN; WISP1 PROTEIN, HUMAN;

EID: 84959515677     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2015.10.013     Document Type: Review
Times cited : (106)

References (114)
  • 1
    • 84902765162 scopus 로고    scopus 로고
    • The incremental prognostic value of myocardial fibrosis in patients with non-ischemic cardiomyopathy without congestive heart failure
    • P.G. Masci, C. Doulaptsis, E. Bertella, A. Del Torto, R. Symons, G. Pontone, and et al. The incremental prognostic value of myocardial fibrosis in patients with non-ischemic cardiomyopathy without congestive heart failure Circ Heart Fail 7 2014 448 456
    • (2014) Circ Heart Fail , vol.7 , pp. 448-456
    • Masci, P.G.1    Doulaptsis, C.2    Bertella, E.3    Del Torto, A.4    Symons, R.5    Pontone, G.6
  • 2
    • 84886644443 scopus 로고    scopus 로고
    • Usefulness of high-sensitivity cardiac troponin T and brain natriuretic peptide as biomarkers of myocardial fibrosis in patients with hypertrophic cardiomyopathy
    • T. Kawasaki, C. Sakai, K. Harimoto, M. Yamano, S. Miki, and T. Kamitani Usefulness of high-sensitivity cardiac troponin T and brain natriuretic peptide as biomarkers of myocardial fibrosis in patients with hypertrophic cardiomyopathy Am J Cardiol 112 2013 867 872
    • (2013) Am J Cardiol , vol.112 , pp. 867-872
    • Kawasaki, T.1    Sakai, C.2    Harimoto, K.3    Yamano, M.4    Miki, S.5    Kamitani, T.6
  • 3
    • 84902491754 scopus 로고    scopus 로고
    • Targeting the unfolded protein response in heart diseases
    • M. Liu, and S.C. Dudley Jr. Targeting the unfolded protein response in heart diseases Expert Opin Ther Targets 2014 1 5
    • (2014) Expert Opin Ther Targets , pp. 1-5
    • Liu, M.1    Dudley, S.C.2
  • 5
    • 84901440560 scopus 로고    scopus 로고
    • Integrins alphavbeta5 and alphavbeta3 promote latent TGF-beta1 activation by human cardiac fibroblast contraction
    • V. Sarrazy, A. Koehler, M. Chow, E. Zimina, C.X. Li, H. Kato, and et al. Integrins alphavbeta5 and alphavbeta3 promote latent TGF-beta1 activation by human cardiac fibroblast contraction Cardiovasc Res 102 2014 407 417
    • (2014) Cardiovasc Res , vol.102 , pp. 407-417
    • Sarrazy, V.1    Koehler, A.2    Chow, M.3    Zimina, E.4    Li, C.X.5    Kato, H.6
  • 6
    • 84899061619 scopus 로고    scopus 로고
    • Targeting cardiac fibroblasts to treat fibrosis of the heart: Focus on HDACs
    • K.B. Schuetze, T.A. McKinsey, and C.S. Long Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs J Mol Cell Cardiol 70 2014 100 107
    • (2014) J Mol Cell Cardiol , vol.70 , pp. 100-107
    • Schuetze, K.B.1    McKinsey, T.A.2    Long, C.S.3
  • 7
    • 84876002562 scopus 로고    scopus 로고
    • Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions
    • Q. Mao, C.X. Lin, X.L. Liang, J.S. Gao, and B. Xu Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actions Mol Med Rep 7 2013 1617 1623
    • (2013) Mol Med Rep , vol.7 , pp. 1617-1623
    • Mao, Q.1    Lin, C.X.2    Liang, X.L.3    Gao, J.S.4    Xu, B.5
  • 8
    • 84899044784 scopus 로고    scopus 로고
    • Cardiac fibroblast in development and wound healing
    • A. Deb, and E. Ubil Cardiac fibroblast in development and wound healing J Mol Cell Cardiol 70 2014 47 55
    • (2014) J Mol Cell Cardiol , vol.70 , pp. 47-55
    • Deb, A.1    Ubil, E.2
  • 10
    • 84896935441 scopus 로고    scopus 로고
    • Relaxin inhibit cardiac fibrosis induced by phorbol 12-myristate 13-acetate
    • Y.P. Wang, P. Wang, L. Dong, H. Chen, Y.Q. Wu, H.W. Li, and et al. Relaxin inhibit cardiac fibrosis induced by phorbol 12-myristate 13-acetate Biomed Environ Sci 27 2014 138 141
    • (2014) Biomed Environ Sci , vol.27 , pp. 138-141
    • Wang, Y.P.1    Wang, P.2    Dong, L.3    Chen, H.4    Wu, Y.Q.5    Li, H.W.6
  • 11
    • 84941599192 scopus 로고    scopus 로고
    • Chronic high fat diet induces cardiac hypertrophy and fibrosis in mice
    • Z. Wang, L. Li, H. Zhao, S. Peng, and Z. Zuo Chronic high fat diet induces cardiac hypertrophy and fibrosis in mice Metab Clin Exp 64 2015 917 925
    • (2015) Metab Clin Exp , vol.64 , pp. 917-925
    • Wang, Z.1    Li, L.2    Zhao, H.3    Peng, S.4    Zuo, Z.5
  • 12
  • 14
    • 84875069394 scopus 로고
    • Fibroblasts in post-infarction inflammation and cardiac repair
    • W. Chen, and N.G. Frangogiannis Fibroblasts in post-infarction inflammation and cardiac repair Biochim Biophys Acta 2013 1833 945 953
    • (1833) Biochim Biophys Acta , vol.2013 , pp. 945-953
    • Chen, W.1    Frangogiannis, N.G.2
  • 15
    • 84874969415 scopus 로고    scopus 로고
    • The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction
    • F.A. van Nieuwenhoven, and N.A. Turner The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction Vasc Pharmacol 58 2013 182 188
    • (2013) Vasc Pharmacol , vol.58 , pp. 182-188
    • Van Nieuwenhoven, F.A.1    Turner, N.A.2
  • 17
    • 84880901534 scopus 로고    scopus 로고
    • The role of cardiac fibroblasts in extracellular matrix-mediated signaling during normal and pathological cardiac development
    • K.E. Sullivan, and L.D. Black The role of cardiac fibroblasts in extracellular matrix-mediated signaling during normal and pathological cardiac development J Biomech Eng 135 2013 71001
    • (2013) J Biomech Eng , vol.135 , pp. 71001
    • Sullivan, K.E.1    Black, L.D.2
  • 18
    • 84857192566 scopus 로고    scopus 로고
    • Wnt1/betacatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair
    • J. Duan, C. Gherghe, D. Liu, E. Hamlett, L. Srikantha, L. Rodgers, and et al. Wnt1/betacatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair EMBO J 31 2012 429 442
    • (2012) EMBO J , vol.31 , pp. 429-442
    • Duan, J.1    Gherghe, C.2    Liu, D.3    Hamlett, E.4    Srikantha, L.5    Rodgers, L.6
  • 19
    • 84860376241 scopus 로고    scopus 로고
    • Fibroproliferative disorders and their mechanobiology
    • C. Huang, and R. Ogawa Fibroproliferative disorders and their mechanobiology Connect Tissue Res 53 2012 187 196
    • (2012) Connect Tissue Res , vol.53 , pp. 187-196
    • Huang, C.1    Ogawa, R.2
  • 20
    • 84882239726 scopus 로고    scopus 로고
    • Plasma rich in growth factors promotes bone tissue regeneration by stimulating proliferation, migration, and autocrine secretion in primary human osteoblasts
    • E. Anitua, R. Tejero, M.M. Zalduendo, and G. Orive Plasma rich in growth factors promotes bone tissue regeneration by stimulating proliferation, migration, and autocrine secretion in primary human osteoblasts J Periodontol 84 2013 1180 1190
    • (2013) J Periodontol , vol.84 , pp. 1180-1190
    • Anitua, E.1    Tejero, R.2    Zalduendo, M.M.3    Orive, G.4
  • 21
    • 84900796850 scopus 로고    scopus 로고
    • The potential of targeting Wnt/beta-catenin in colon cancer
    • A. Sebio, M. Kahn, and H.J. Lenz The potential of targeting Wnt/beta-catenin in colon cancer Expert Opin Ther Targets 18 2014 611 615
    • (2014) Expert Opin Ther Targets , vol.18 , pp. 611-615
    • Sebio, A.1    Kahn, M.2    Lenz, H.J.3
  • 22
    • 1542346154 scopus 로고    scopus 로고
    • Wnt signalling via the epidermal growth factor receptor: A role in breast cancer?
    • E.A. Musgrove Wnt signalling via the epidermal growth factor receptor: a role in breast cancer? Breast Cancer Res 6 2004 65 68
    • (2004) Breast Cancer Res , vol.6 , pp. 65-68
    • Musgrove, E.A.1
  • 23
    • 84885719487 scopus 로고    scopus 로고
    • Insights into insect wing origin provided by functional analysis of vestigial in the red flour beetle, Tribolium castaneum
    • C.M. Clark-Hachtel, D.M. Linz, and Y. Tomoyasu Insights into insect wing origin provided by functional analysis of vestigial in the red flour beetle, Tribolium castaneum Proc Natl Acad Sci U S A 110 2013 16951 16956
    • (2013) Proc Natl Acad Sci U S A , vol.110 , pp. 16951-16956
    • Clark-Hachtel, C.M.1    Linz, D.M.2    Tomoyasu, Y.3
  • 25
    • 84879840404 scopus 로고    scopus 로고
    • Structural studies of Wnts and identification of an LRP6 binding site
    • M.L. Chu, V.E. Ahn, H.J. Choi, D.L. Daniels, R. Nusse, and W.I. Weis Structural studies of Wnts and identification of an LRP6 binding site Structure 21 2013 1235 1242
    • (2013) Structure , vol.21 , pp. 1235-1242
    • Chu, M.L.1    Ahn, V.E.2    Choi, H.J.3    Daniels, D.L.4    Nusse, R.5    Weis, W.I.6
  • 26
    • 84880169315 scopus 로고    scopus 로고
    • Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling
    • C.G. Miao, Y.Y. Yang, X. He, X.F. Li, C. Huang, Y. Huang, and et al. Wnt signaling pathway in rheumatoid arthritis, with special emphasis on the different roles in synovial inflammation and bone remodeling Cell Signal 25 2013 2069 2078
    • (2013) Cell Signal , vol.25 , pp. 2069-2078
    • Miao, C.G.1    Yang, Y.Y.2    He, X.3    Li, X.F.4    Huang, C.5    Huang, Y.6
  • 28
    • 84899844060 scopus 로고    scopus 로고
    • Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/beta-catenin signaling
    • R.D. Prinz, C.M. Willis, T.H. van Kuppevelt, and M. Kluppel Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/beta-catenin signaling PLoS One 9 2014 e92381
    • (2014) PLoS One , vol.9 , pp. e92381
    • Prinz, R.D.1    Willis, C.M.2    Van Kuppevelt, T.H.3    Kluppel, M.4
  • 29
    • 77955869484 scopus 로고    scopus 로고
    • Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1
    • X. Zhou, S. Yu, D.M. Zhao, J.T. Harty, V.P. Badovinac, and H.H. Xue Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1 Immunity 33 2010 229 240
    • (2010) Immunity , vol.33 , pp. 229-240
    • Zhou, X.1    Yu, S.2    Zhao, D.M.3    Harty, J.T.4    Badovinac, V.P.5    Xue, H.H.6
  • 30
    • 84925371635 scopus 로고    scopus 로고
    • C3a and C5a receptor antagonists ameliorate endothelial-myofibroblast transition via the Wnt/beta-catenin signaling pathway in diabetic kidney disease
    • L. Li, L. Chen, J. Zang, X. Tang, Y. Liu, J. Zhang, and et al. C3a and C5a receptor antagonists ameliorate endothelial-myofibroblast transition via the Wnt/beta-catenin signaling pathway in diabetic kidney disease Metab Clin Exp 64 2015 597 610
    • (2015) Metab Clin Exp , vol.64 , pp. 597-610
    • Li, L.1    Chen, L.2    Zang, J.3    Tang, X.4    Liu, Y.5    Zhang, J.6
  • 31
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • B.T. MacDonald, K. Tamai, and X. He Wnt/beta-catenin signaling: components, mechanisms, and diseases Dev Cell 17 2009 9 26
    • (2009) Dev Cell , vol.17 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 32
    • 79955492739 scopus 로고    scopus 로고
    • Fas-associated factor 1 antagonizes Wnt signaling by promoting beta-catenin degradation
    • L. Zhang, F. Zhou, T. van Laar, J. Zhang, H. van Dam, and P. Ten Dijke Fas-associated factor 1 antagonizes Wnt signaling by promoting beta-catenin degradation Mol Biol Cell 22 2011 1617 1624
    • (2011) Mol Biol Cell , vol.22 , pp. 1617-1624
    • Zhang, L.1    Zhou, F.2    Van Laar, T.3    Zhang, J.4    Van Dam, H.5    Ten Dijke, P.6
  • 33
    • 77955846908 scopus 로고    scopus 로고
    • The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner
    • I. Struewing, T. Boyechko, C. Barnett, M. Beildeck, S.W. Byers, and C.D. Mao The balance of TCF7L2 variants with differential activities in Wnt-signaling is regulated by lithium in a GSK3beta-independent manner Biochem Biophys Res Commun 399 2010 245 250
    • (2010) Biochem Biophys Res Commun , vol.399 , pp. 245-250
    • Struewing, I.1    Boyechko, T.2    Barnett, C.3    Beildeck, M.4    Byers, S.W.5    Mao, C.D.6
  • 34
    • 37349108182 scopus 로고    scopus 로고
    • Adherens junction breakdown in the periderm following cadmium administration in the chick embryo: Distribution of cadherins and associated molecules
    • J. Thompson, L. Wong, P.S. Lau, and J. Bannigan Adherens junction breakdown in the periderm following cadmium administration in the chick embryo: distribution of cadherins and associated molecules Reprod Toxicol 25 2008 39 46
    • (2008) Reprod Toxicol , vol.25 , pp. 39-46
    • Thompson, J.1    Wong, L.2    Lau, P.S.3    Bannigan, J.4
  • 35
    • 84875216922 scopus 로고    scopus 로고
    • The WNT signaling pathway from ligand secretion to gene transcription: Molecular mechanisms and pharmacological targets
    • H.A. Baarsma, M. Konigshoff, and R. Gosens The WNT signaling pathway from ligand secretion to gene transcription: molecular mechanisms and pharmacological targets Pharmacol Ther 138 2013 66 83
    • (2013) Pharmacol Ther , vol.138 , pp. 66-83
    • Baarsma, H.A.1    Konigshoff, M.2    Gosens, R.3
  • 36
    • 84896869459 scopus 로고    scopus 로고
    • ROS, Notch, and Wnt signaling pathways: Crosstalk between three major regulators of cardiovascular biology
    • C. Caliceti, P. Nigro, P. Rizzo, and R. Ferrari ROS, Notch, and Wnt signaling pathways: crosstalk between three major regulators of cardiovascular biology Biomed Res Int 2014 2014 318714
    • (2014) Biomed Res Int , vol.2014 , pp. 318714
    • Caliceti, C.1    Nigro, P.2    Rizzo, P.3    Ferrari, R.4
  • 38
    • 84856334082 scopus 로고    scopus 로고
    • Mapping of the Wnt/beta-catenin/TCF response elements in the human versican promoter
    • M. Rahmani, J.M. Carthy, and B.M. McManus Mapping of the Wnt/beta-catenin/TCF response elements in the human versican promoter Methods Mol Biol 836 2012 35 52
    • (2012) Methods Mol Biol , vol.836 , pp. 35-52
    • Rahmani, M.1    Carthy, J.M.2    McManus, B.M.3
  • 39
    • 84856191525 scopus 로고    scopus 로고
    • Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers
    • B.D. White, A.J. Chien, and D.W. Dawson Dysregulation of Wnt/beta-catenin signaling in gastrointestinal cancers Gastroenterology 142 2012 219 232
    • (2012) Gastroenterology , vol.142 , pp. 219-232
    • White, B.D.1    Chien, A.J.2    Dawson, D.W.3
  • 40
    • 84897938327 scopus 로고    scopus 로고
    • Regulation of Wnt/beta-catenin signaling by posttranslational modifications
    • C. Gao, G. Xiao, and J. Hu Regulation of Wnt/beta-catenin signaling by posttranslational modifications Cell Biosci 4 2014 13
    • (2014) Cell Biosci , vol.4 , pp. 13
    • Gao, C.1    Xiao, G.2    Hu, J.3
  • 41
    • 77952690895 scopus 로고    scopus 로고
    • Beta-catenin - A supporting role in the skeleton
    • N. Case, and J. Rubin Beta-catenin - a supporting role in the skeleton J Cell Biochem 110 2010 545 553
    • (2010) J Cell Biochem , vol.110 , pp. 545-553
    • Case, N.1    Rubin, J.2
  • 42
    • 84875249340 scopus 로고    scopus 로고
    • Beta-catenin versus the other armadillo catenins: Assessing our current view of canonical Wnt signaling
    • R.K. Miller, J.Y. Hong, W.A. Munoz, and P.D. McCrea Beta-catenin versus the other armadillo catenins: assessing our current view of canonical Wnt signaling Prog Mol Biol Transl Sci 116 2013 387 407
    • (2013) Prog Mol Biol Transl Sci , vol.116 , pp. 387-407
    • Miller, R.K.1    Hong, J.Y.2    Munoz, W.A.3    McCrea, P.D.4
  • 43
    • 84862171364 scopus 로고    scopus 로고
    • The many faces and functions of beta-catenin
    • T. Valenta, G. Hausmann, and K. Basler The many faces and functions of beta-catenin EMBO J 31 2012 2714 2736
    • (2012) EMBO J , vol.31 , pp. 2714-2736
    • Valenta, T.1    Hausmann, G.2    Basler, K.3
  • 44
    • 80053466165 scopus 로고    scopus 로고
    • Wnt/Ca2 + signaling pathway: A brief overview
    • A. De Wnt/Ca2 + signaling pathway: a brief overview Acta Biochim Biophys Sin 43 2011 745 756
    • (2011) Acta Biochim Biophys Sin , vol.43 , pp. 745-756
    • De, A.1
  • 45
    • 70350058688 scopus 로고    scopus 로고
    • EP2 receptor mediated cAMP release is augmented by PGF 2 alpha activation of the FP receptor via the calcium-calmodulin pathway
    • A.B. Abera, K.J. Sales, R.D. Catalano, A.A. Katz, and H.N. Jabbour EP2 receptor mediated cAMP release is augmented by PGF 2 alpha activation of the FP receptor via the calcium-calmodulin pathway Cell Signal 22 2010 71 79
    • (2010) Cell Signal , vol.22 , pp. 71-79
    • Abera, A.B.1    Sales, K.J.2    Catalano, R.D.3    Katz, A.A.4    Jabbour, H.N.5
  • 46
    • 84875058649 scopus 로고    scopus 로고
    • Role of the Wnt-Frizzled system in cardiac pathophysiology: A rapidly developing, poorly understood area with enormous potential
    • K. Dawson, M. Aflaki, and S. Nattel Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential J Physiol 591 2013 1409 1432
    • (2013) J Physiol , vol.591 , pp. 1409-1432
    • Dawson, K.1    Aflaki, M.2    Nattel, S.3
  • 47
    • 1542298276 scopus 로고    scopus 로고
    • Peroxisomal localization in the developing mouse cerebellum: Implications for neuronal abnormalities related to deficiencies in peroxisomes
    • T. Nagase, N. Shimozawa, Y. Takemoto, Y. Suzuki, M. Komori, and N. Kondo Peroxisomal localization in the developing mouse cerebellum: implications for neuronal abnormalities related to deficiencies in peroxisomes Biochim Biophys Acta 1671 2004 26 33
    • (2004) Biochim Biophys Acta , vol.1671 , pp. 26-33
    • Nagase, T.1    Shimozawa, N.2    Takemoto, Y.3    Suzuki, Y.4    Komori, M.5    Kondo, N.6
  • 48
    • 84879127872 scopus 로고    scopus 로고
    • The calcineurin-NFAT pathway negatively regulates megakaryopoiesis
    • A. Zaslavsky, S.T. Chou, K. Schadler, A. Lieberman, M. Pimkin, Y.J. Kim, and et al. The calcineurin-NFAT pathway negatively regulates megakaryopoiesis Blood 121 2013 3205 3215
    • (2013) Blood , vol.121 , pp. 3205-3215
    • Zaslavsky, A.1    Chou, S.T.2    Schadler, K.3    Lieberman, A.4    Pimkin, M.5    Kim, Y.J.6
  • 49
    • 84899485738 scopus 로고    scopus 로고
    • Transcriptional regulation of arterial differentiation via Wnt, Sox and Notch
    • M.F. Morini, and E. Dejana Transcriptional regulation of arterial differentiation via Wnt, Sox and Notch Curr Opin Hematol 21 2014 229 234
    • (2014) Curr Opin Hematol , vol.21 , pp. 229-234
    • Morini, M.F.1    Dejana, E.2
  • 50
    • 34447131518 scopus 로고    scopus 로고
    • The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition
    • S.K. Dissanayake, M. Wade, C.E. Johnson, M.P. O'Connell, P.D. Leotlela, A.D. French, and et al. The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition J Biol Chem 282 2007 17259 17271
    • (2007) J Biol Chem , vol.282 , pp. 17259-17271
    • Dissanayake, S.K.1    Wade, M.2    Johnson, C.E.3    O'Connell, M.P.4    Leotlela, P.D.5    French, A.D.6
  • 51
    • 79551587194 scopus 로고    scopus 로고
    • Strange as it may seem: The many links between Wnt signaling, planar cell polarity, and cilia
    • J.B. Wallingford, and B. Mitchell Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia Genes Dev 25 2011 201 213
    • (2011) Genes Dev , vol.25 , pp. 201-213
    • Wallingford, J.B.1    Mitchell, B.2
  • 52
    • 84895909035 scopus 로고    scopus 로고
    • Mitotic spindle asymmetry: A Wnt/PCP-regulated mechanism generating asymmetrical division in cortical precursors
    • D. Delaunay, V. Cortay, D. Patti, K. Knoblauch, and C. Dehay Mitotic spindle asymmetry: a Wnt/PCP-regulated mechanism generating asymmetrical division in cortical precursors Cell Rep 6 2014 400 414
    • (2014) Cell Rep , vol.6 , pp. 400-414
    • Delaunay, D.1    Cortay, V.2    Patti, D.3    Knoblauch, K.4    Dehay, C.5
  • 53
    • 84896725023 scopus 로고    scopus 로고
    • The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells
    • C. Artus, F. Glacial, K. Ganeshamoorthy, N. Ziegler, M. Godet, T. Guilbert, and et al. The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells J Cereb Blood Flow Metab 34 2014 433 440
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 433-440
    • Artus, C.1    Glacial, F.2    Ganeshamoorthy, K.3    Ziegler, N.4    Godet, M.5    Guilbert, T.6
  • 55
    • 84895192951 scopus 로고    scopus 로고
    • WNT/Frizzled signalling: Receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3
    • J.P. Dijksterhuis, J. Petersen, and G. Schulte WNT/Frizzled signalling: receptor-ligand selectivity with focus on FZD-G protein signalling and its physiological relevance: IUPHAR Review 3 Br J Pharmacol 171 2014 1195 1209
    • (2014) Br J Pharmacol , vol.171 , pp. 1195-1209
    • Dijksterhuis, J.P.1    Petersen, J.2    Schulte, G.3
  • 56
    • 84877144141 scopus 로고    scopus 로고
    • Polarizing pathways: Balancing endothelial polarity, permeability, and lumen formation
    • C.O. Lizama, and A.C. Zovein Polarizing pathways: balancing endothelial polarity, permeability, and lumen formation Exp Cell Res 319 2013 1247 1254
    • (2013) Exp Cell Res , vol.319 , pp. 1247-1254
    • Lizama, C.O.1    Zovein, A.C.2
  • 57
    • 84892367590 scopus 로고    scopus 로고
    • Structural and temporal requirements of Wnt/PCP protein Vangl2 function for convergence and extension movements and facial branchiomotor neuron migration in zebrafish
    • X. Pan, V. Sittaramane, S. Gurung, and A. Chandrasekhar Structural and temporal requirements of Wnt/PCP protein Vangl2 function for convergence and extension movements and facial branchiomotor neuron migration in zebrafish Mech Dev 131 2014 1 14
    • (2014) Mech Dev , vol.131 , pp. 1-14
    • Pan, X.1    Sittaramane, V.2    Gurung, S.3    Chandrasekhar, A.4
  • 58
    • 84860143671 scopus 로고    scopus 로고
    • Novel therapeutic approaches to post-infarction remodelling
    • D. Fraccarollo, P. Galuppo, and J. Bauersachs Novel therapeutic approaches to post-infarction remodelling Cardiovasc Res 94 2012 293 303
    • (2012) Cardiovasc Res , vol.94 , pp. 293-303
    • Fraccarollo, D.1    Galuppo, P.2    Bauersachs, J.3
  • 59
    • 84904259334 scopus 로고    scopus 로고
    • Cryptotanshinone attenuates cardiac fibrosis via downregulation of COX-2, NOX-2 and NOX-4
    • Y. Ma, H. Li, Z. Yue, J. Guo, S. Xu, J. Xu, and et al. Cryptotanshinone attenuates cardiac fibrosis via downregulation of COX-2, NOX-2 and NOX-4 J Cardiovasc Pharmacol 64 2014 28 37
    • (2014) J Cardiovasc Pharmacol , vol.64 , pp. 28-37
    • Ma, Y.1    Li, H.2    Yue, Z.3    Guo, J.4    Xu, S.5    Xu, J.6
  • 60
    • 84899982846 scopus 로고    scopus 로고
    • MiR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-beta/Smad3 signaling
    • Y. Zhang, X.R. Huang, L.H. Wei, A.C. Chung, C.M. Yu, and H.Y. Lan miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-beta/Smad3 signaling Mol Ther 22 2014 974 985
    • (2014) Mol Ther , vol.22 , pp. 974-985
    • Zhang, Y.1    Huang, X.R.2    Wei, L.H.3    Chung, A.C.4    Yu, C.M.5    Lan, H.Y.6
  • 61
    • 84899088319 scopus 로고    scopus 로고
    • Cardiac fibroblasts: The good, the bad, the ugly, the beautiful
    • J.N. Weiss, and J. Sadoshima Cardiac fibroblasts: the good, the bad, the ugly, the beautiful J Mol Cell Cardiol 70 2014 1-1
    • (2014) J Mol Cell Cardiol , vol.70 , pp. 1
    • Weiss, J.N.1    Sadoshima, J.2
  • 62
    • 84895073611 scopus 로고    scopus 로고
    • Protective effect of lycopene on cardiac function and myocardial fibrosis after acute myocardial infarction in rats via the modulation of p38 and MMP-9
    • X. Wang, H. Lv, Y. Gu, H. Cao, Y. Tang, H. Chen, and et al. Protective effect of lycopene on cardiac function and myocardial fibrosis after acute myocardial infarction in rats via the modulation of p38 and MMP-9 J Mol Histol 45 2014 113 120
    • (2014) J Mol Histol , vol.45 , pp. 113-120
    • Wang, X.1    Lv, H.2    Gu, Y.3    Cao, H.4    Tang, Y.5    Chen, H.6
  • 63
    • 84883219467 scopus 로고    scopus 로고
    • Roles of transient receptor potential canonical (TRPC) channels and reverse-mode Na +/Ca2 + exchanger on cell proliferation in human cardiac fibroblasts: Effects of transforming growth factor beta1
    • K. Ikeda, T. Nakajima, Y. Yamamoto, N. Takano, T. Tanaka, H. Kikuchi, and et al. Roles of transient receptor potential canonical (TRPC) channels and reverse-mode Na +/Ca2 + exchanger on cell proliferation in human cardiac fibroblasts: effects of transforming growth factor beta1 Cell Calcium 54 2013 213 225
    • (2013) Cell Calcium , vol.54 , pp. 213-225
    • Ikeda, K.1    Nakajima, T.2    Yamamoto, Y.3    Takano, N.4    Tanaka, T.5    Kikuchi, H.6
  • 64
    • 84889091885 scopus 로고    scopus 로고
    • Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy
    • Y.J. Shimada, J.J. Passeri, A.L. Baggish, C. O'Callaghan, P.A. Lowry, G. Yannekis, and et al. Effects of losartan on left ventricular hypertrophy and fibrosis in patients with nonobstructive hypertrophic cardiomyopathy JACC Heart Fail 1 2013 480 487
    • (2013) JACC Heart Fail , vol.1 , pp. 480-487
    • Shimada, Y.J.1    Passeri, J.J.2    Baggish, A.L.3    O'Callaghan, C.4    Lowry, P.A.5    Yannekis, G.6
  • 65
    • 84878771646 scopus 로고    scopus 로고
    • IL-1beta suppresses TGF-beta-mediated myofibroblast differentiation in cardiac fibroblasts
    • H. Bronnum, T. Eskildsen, D.C. Andersen, M. Schneider, and S.P. Sheikh IL-1beta suppresses TGF-beta-mediated myofibroblast differentiation in cardiac fibroblasts Growth Factors 31 2013 81 89
    • (2013) Growth Factors , vol.31 , pp. 81-89
    • Bronnum, H.1    Eskildsen, T.2    Andersen, D.C.3    Schneider, M.4    Sheikh, S.P.5
  • 66
    • 84876856286 scopus 로고    scopus 로고
    • Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts
    • A. Maqbool, K.E. Hemmings, D.J. O'Regan, S.G. Ball, K.E. Porter, and N.A. Turner Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts Matrix Biol 32 2013 208 214
    • (2013) Matrix Biol , vol.32 , pp. 208-214
    • Maqbool, A.1    Hemmings, K.E.2    O'Regan, D.J.3    Ball, S.G.4    Porter, K.E.5    Turner, N.A.6
  • 67
    • 84883167643 scopus 로고    scopus 로고
    • Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation
    • N. Gaber, M. Gagliardi, P. Patel, C. Kinnear, C. Zhang, D. Chitayat, and et al. Fetal reprogramming and senescence in hypoplastic left heart syndrome and in human pluripotent stem cells during cardiac differentiation Am J Pathol 183 2013 720 734
    • (2013) Am J Pathol , vol.183 , pp. 720-734
    • Gaber, N.1    Gagliardi, M.2    Patel, P.3    Kinnear, C.4    Zhang, C.5    Chitayat, D.6
  • 68
    • 84891887947 scopus 로고    scopus 로고
    • Imaging aspects of the tumor stroma with therapeutic implications
    • L. Narunsky, R. Oren, F. Bochner, and M. Neeman Imaging aspects of the tumor stroma with therapeutic implications Pharmacol Ther 141 2014 192 208
    • (2014) Pharmacol Ther , vol.141 , pp. 192-208
    • Narunsky, L.1    Oren, R.2    Bochner, F.3    Neeman, M.4
  • 69
    • 84880543015 scopus 로고    scopus 로고
    • The ginsenoside Rg1 prevents transverse aortic constriction-induced left ventricular hypertrophy and cardiac dysfunction by inhibiting fibrosis and enhancing angiogenesis
    • Y.J. Zhang, X.L. Zhang, M.H. Li, J. Iqbal, C.V. Bourantas, J.J. Li, and et al. The ginsenoside Rg1 prevents transverse aortic constriction-induced left ventricular hypertrophy and cardiac dysfunction by inhibiting fibrosis and enhancing angiogenesis J Cardiovasc Pharmacol 62 2013 50 57
    • (2013) J Cardiovasc Pharmacol , vol.62 , pp. 50-57
    • Zhang, Y.J.1    Zhang, X.L.2    Li, M.H.3    Iqbal, J.4    Bourantas, C.V.5    Li, J.J.6
  • 70
    • 84887486685 scopus 로고    scopus 로고
    • Cornelia de Lange syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts
    • A. Pistocchi, G. Fazio, A. Cereda, L. Ferrari, L.R. Bettini, G. Messina, and et al. Cornelia de Lange syndrome: NIPBL haploinsufficiency downregulates canonical Wnt pathway in zebrafish embryos and patients fibroblasts Cell Death Dis 4 2013 e866
    • (2013) Cell Death Dis , vol.4 , pp. e866
    • Pistocchi, A.1    Fazio, G.2    Cereda, A.3    Ferrari, L.4    Bettini, L.R.5    Messina, G.6
  • 71
    • 84901057904 scopus 로고    scopus 로고
    • Loss of microRNA-155 protects the heart from pathological cardiac hypertrophy
    • H.Y. Seok, J. Chen, M. Kataoka, Z.P. Huang, J. Ding, J. Yan, and et al. Loss of microRNA-155 protects the heart from pathological cardiac hypertrophy Circ Res 114 2014 1585 1595
    • (2014) Circ Res , vol.114 , pp. 1585-1595
    • Seok, H.Y.1    Chen, J.2    Kataoka, M.3    Huang, Z.P.4    Ding, J.5    Yan, J.6
  • 72
    • 84893032153 scopus 로고    scopus 로고
    • Effect of oxygen on cardiac differentiation in mouse iPS cells: Role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling
    • T.L. Medley, M. Furtado, N.T. Lam, R. Idrizi, D. Williams, P.J. Verma, and et al. Effect of oxygen on cardiac differentiation in mouse iPS cells: role of hypoxia inducible factor-1 and Wnt/beta-catenin signaling PLoS One 8 2013 e80280
    • (2013) PLoS One , vol.8 , pp. e80280
    • Medley, T.L.1    Furtado, M.2    Lam, N.T.3    Idrizi, R.4    Williams, D.5    Verma, P.J.6
  • 73
    • 84869992760 scopus 로고    scopus 로고
    • Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit + cells
    • E. Yaniz-Galende, J. Chen, E. Chemaly, L. Liang, J.S. Hulot, L. McCollum, and et al. Stem cell factor gene transfer promotes cardiac repair after myocardial infarction via in situ recruitment and expansion of c-kit + cells Circ Res 111 2012 1434 1445
    • (2012) Circ Res , vol.111 , pp. 1434-1445
    • Yaniz-Galende, E.1    Chen, J.2    Chemaly, E.3    Liang, L.4    Hulot, J.S.5    McCollum, L.6
  • 74
    • 82355191817 scopus 로고    scopus 로고
    • An update on primary hip osteoarthritis including altered Wnt and TGF-beta associated gene expression from the bony component of the disease
    • D.D. Kumarasinghe, B. Hopwood, J.S. Kuliwaba, G.J. Atkins, and N.L. Fazzalari An update on primary hip osteoarthritis including altered Wnt and TGF-beta associated gene expression from the bony component of the disease Rheumatology (Oxford) 50 2011 2166 2175
    • (2011) Rheumatology (Oxford) , vol.50 , pp. 2166-2175
    • Kumarasinghe, D.D.1    Hopwood, B.2    Kuliwaba, J.S.3    Atkins, G.J.4    Fazzalari, N.L.5
  • 75
    • 84870915167 scopus 로고    scopus 로고
    • Canonical Wnt/beta-catenin signaling in epicardial fibrosis of failed pediatric heart allografts with diastolic dysfunction
    • B. Ye, Y. Ge, G. Perens, L. Hong, H. Xu, M.C. Fishbein, and et al. Canonical Wnt/beta-catenin signaling in epicardial fibrosis of failed pediatric heart allografts with diastolic dysfunction Cardiovasc Pathol 22 2013 54 57
    • (2013) Cardiovasc Pathol , vol.22 , pp. 54-57
    • Ye, B.1    Ge, Y.2    Perens, G.3    Hong, L.4    Xu, H.5    Fishbein, M.C.6
  • 76
    • 84939943937 scopus 로고    scopus 로고
    • Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway
    • J. Cao, P.L. Tsenovoy, E.A. Thompson, J.R. Falck, R. Touchon, K. Sodhi, and et al. Agonists of epoxyeicosatrienoic acids reduce infarct size and ameliorate cardiac dysfunction via activation of HO-1 and Wnt1 canonical pathway Prostaglandins Other Lipid Mediat 116-117 2015 76 86
    • (2015) Prostaglandins Other Lipid Mediat , vol.116-117 , pp. 76-86
    • Cao, J.1    Tsenovoy, P.L.2    Thompson, E.A.3    Falck, J.R.4    Touchon, R.5    Sodhi, K.6
  • 77
    • 84891825619 scopus 로고    scopus 로고
    • Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation
    • Q. Xiao, F. Zhang, G. Grassia, Y. Hu, Z. Zhang, Q. Xing, and et al. Matrix metalloproteinase-8 promotes vascular smooth muscle cell proliferation and neointima formation Arterioscler Thromb Vasc Biol 34 2014 90 98
    • (2014) Arterioscler Thromb Vasc Biol , vol.34 , pp. 90-98
    • Xiao, Q.1    Zhang, F.2    Grassia, G.3    Hu, Y.4    Zhang, Z.5    Xing, Q.6
  • 78
    • 84861394103 scopus 로고    scopus 로고
    • The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors
    • A. Acharya, S.T. Baek, G. Huang, B. Eskiocak, S. Goetsch, C.Y. Sung, and et al. The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors Development 139 2012 2139 2149
    • (2012) Development , vol.139 , pp. 2139-2149
    • Acharya, A.1    Baek, S.T.2    Huang, G.3    Eskiocak, B.4    Goetsch, S.5    Sung, C.Y.6
  • 79
    • 84862284813 scopus 로고    scopus 로고
    • Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease
    • A. von Gise, and W.T. Pu Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease Circ Res 110 2012 1628 1645
    • (2012) Circ Res , vol.110 , pp. 1628-1645
    • Von Gise, A.1    Pu, W.T.2
  • 80
    • 84899045255 scopus 로고    scopus 로고
    • Cell-cell interaction in the heart via Wnt/beta-catenin pathway after cardiac injury
    • A. Deb Cell-cell interaction in the heart via Wnt/beta-catenin pathway after cardiac injury Cardiovasc Res 102 2014 214 223
    • (2014) Cardiovasc Res , vol.102 , pp. 214-223
    • Deb, A.1
  • 83
    • 84899037226 scopus 로고    scopus 로고
    • Expression and redistribution of beta-catenin in the cardiac myocytes of left ventricle of spontaneously hypertensive rat
    • Q. Zheng, P. Chen, Z. Xu, F. Li, and X.P. Yi Expression and redistribution of beta-catenin in the cardiac myocytes of left ventricle of spontaneously hypertensive rat J Mol Histol 44 2013 565 573
    • (2013) J Mol Histol , vol.44 , pp. 565-573
    • Zheng, Q.1    Chen, P.2    Xu, Z.3    Li, F.4    Yi, X.P.5
  • 84
    • 33745848407 scopus 로고    scopus 로고
    • Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy
    • E. Garcia-Gras, R. Lombardi, M.J. Giocondo, J.T. Willerson, M.D. Schneider, D.S. Khoury, and et al. Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy J Clin Invest 116 2006 2012 2021
    • (2006) J Clin Invest , vol.116 , pp. 2012-2021
    • Garcia-Gras, E.1    Lombardi, R.2    Giocondo, M.J.3    Willerson, J.T.4    Schneider, M.D.5    Khoury, D.S.6
  • 85
    • 82355190091 scopus 로고    scopus 로고
    • Functions of the Wnt/beta-catenin pathway in an anemia-induced zebrafish model of cardiomyopathy are location dependent
    • T. Hoage, X. Sun, and X. Xu Functions of the Wnt/beta-catenin pathway in an anemia-induced zebrafish model of cardiomyopathy are location dependent Biochem Biophys Res Commun 415 2011 490 496
    • (2011) Biochem Biophys Res Commun , vol.415 , pp. 490-496
    • Hoage, T.1    Sun, X.2    Xu, X.3
  • 86
    • 79955405757 scopus 로고    scopus 로고
    • Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size
    • T. Heallen, M. Zhang, J. Wang, M. Bonilla-Claudio, E. Klysik, R.L. Johnson, and et al. Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size Science 332 2011 458 461
    • (2011) Science , vol.332 , pp. 458-461
    • Heallen, T.1    Zhang, M.2    Wang, J.3    Bonilla-Claudio, M.4    Klysik, E.5    Johnson, R.L.6
  • 88
    • 58149333154 scopus 로고    scopus 로고
    • Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction
    • K. Kobayashi, M. Luo, Y. Zhang, D.C. Wilkes, G. Ge, T. Grieskamp, and et al. Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction Nat Cell Biol 11 2009 46 55
    • (2009) Nat Cell Biol , vol.11 , pp. 46-55
    • Kobayashi, K.1    Luo, M.2    Zhang, Y.3    Wilkes, D.C.4    Ge, G.5    Grieskamp, T.6
  • 89
    • 84866092742 scopus 로고    scopus 로고
    • Secreted and transmembrane wnt inhibitors and activators
    • C.M. Cruciat, and C. Niehrs Secreted and transmembrane wnt inhibitors and activators Cold Spring Harb Perspect Biol 5 2013 a015081
    • (2013) Cold Spring Harb Perspect Biol , vol.5 , pp. a015081
    • Cruciat, C.M.1    Niehrs, C.2
  • 90
    • 84899650478 scopus 로고    scopus 로고
    • The inflammatory response in myocardial injury, repair, and remodelling
    • N.G. Frangogiannis The inflammatory response in myocardial injury, repair, and remodelling Nat Rev Cardiol 11 2014 255 265
    • (2014) Nat Rev Cardiol , vol.11 , pp. 255-265
    • Frangogiannis, N.G.1
  • 92
    • 80054940740 scopus 로고    scopus 로고
    • Secreted frizzled-related protein-1 improves postinfarction scar formation through a modulation of inflammatory response
    • L. Barandon, F. Casassus, L. Leroux, C. Moreau, C. Allieres, J.M. Lamaziere, and et al. Secreted frizzled-related protein-1 improves postinfarction scar formation through a modulation of inflammatory response Arterioscler Thromb Vasc Biol 31 2011 e80 e87
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. e80-e87
    • Barandon, L.1    Casassus, F.2    Leroux, L.3    Moreau, C.4    Allieres, C.5    Lamaziere, J.M.6
  • 93
    • 84937540149 scopus 로고    scopus 로고
    • Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy
    • P. Sklepkiewicz, T. Shiomi, R. Kaur, J. Sun, S. Kwon, B. Mercer, and et al. Loss of secreted frizzled-related protein-1 leads to deterioration of cardiac function in mice and plays a role in human cardiomyopathy Circ Heart Fail 8 2015 362 372
    • (2015) Circ Heart Fail , vol.8 , pp. 362-372
    • Sklepkiewicz, P.1    Shiomi, T.2    Kaur, R.3    Sun, J.4    Kwon, S.5    Mercer, B.6
  • 94
    • 84860271216 scopus 로고    scopus 로고
    • Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: Induction of promoter demethylation and histone modification causing inhibition of Wnt signaling
    • H. Shin, J.H. Kim, Y.S. Lee, and Y.C. Lee Change in gene expression profiles of secreted frizzled-related proteins (SFRPs) by sodium butyrate in gastric cancers: induction of promoter demethylation and histone modification causing inhibition of Wnt signaling Int J Oncol 40 2012 1533 1542
    • (2012) Int J Oncol , vol.40 , pp. 1533-1542
    • Shin, H.1    Kim, J.H.2    Lee, Y.S.3    Lee, Y.C.4
  • 95
    • 78650489190 scopus 로고    scopus 로고
    • Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction
    • W. He, L. Zhang, A. Ni, Z. Zhang, M. Mirotsou, L. Mao, and et al. Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction Proc Natl Acad Sci U S A 107 2010 21110 21115
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 21110-21115
    • He, W.1    Zhang, L.2    Ni, A.3    Zhang, Z.4    Mirotsou, M.5    Mao, L.6
  • 96
    • 84902086236 scopus 로고    scopus 로고
    • The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure
    • E.T. Askevold, P. Aukrust, S.H. Nymo, I.G. Lunde, O.J. Kaasboll, S. Aakhus, and et al. The cardiokine secreted Frizzled-related protein 3, a modulator of Wnt signalling, in clinical and experimental heart failure J Intern Med 275 2013 621 630
    • (2013) J Intern Med , vol.275 , pp. 621-630
    • Askevold, E.T.1    Aukrust, P.2    Nymo, S.H.3    Lunde, I.G.4    Kaasboll, O.J.5    Aakhus, S.6
  • 97
    • 84869193037 scopus 로고    scopus 로고
    • Role of WNT/beta-catenin signaling in rejuvenating myogenic differentiation of aged mesenchymal stem cells from cardiac patients
    • K.R. Brunt, Y. Zhang, A. Mihic, M. Li, S.H. Li, P. Xue, and et al. Role of WNT/beta-catenin signaling in rejuvenating myogenic differentiation of aged mesenchymal stem cells from cardiac patients Am J Pathol 181 2012 2067 2078
    • (2012) Am J Pathol , vol.181 , pp. 2067-2078
    • Brunt, K.R.1    Zhang, Y.2    Mihic, A.3    Li, M.4    Li, S.H.5    Xue, P.6
  • 98
    • 78149250947 scopus 로고    scopus 로고
    • Secreted frizzled related protein 4 reduces fibrosis scar size and ameliorates cardiac function after ischemic injury
    • K. Matsushima, T. Suyama, C. Takenaka, N. Nishishita, K. Ikeda, Y. Ikada, and et al. Secreted frizzled related protein 4 reduces fibrosis scar size and ameliorates cardiac function after ischemic injury Tissue Eng A 16 2010 3329 3341
    • (2010) Tissue Eng A , vol.16 , pp. 3329-3341
    • Matsushima, K.1    Suyama, T.2    Takenaka, C.3    Nishishita, N.4    Ikeda, K.5    Ikada, Y.6
  • 99
    • 84925735151 scopus 로고    scopus 로고
    • Klotho and chronic kidney disease
    • M.C. Hu, M. Kuro-o, and O.W. Moe Klotho and chronic kidney disease Contrib Nephrol 180 2013 47 63
    • (2013) Contrib Nephrol , vol.180 , pp. 47-63
    • Hu, M.C.1    Kuro-O, M.2    Moe, O.W.3
  • 100
    • 84878944974 scopus 로고    scopus 로고
    • Dapper-1 induces myocardial remodeling through activation of canonical Wnt signaling in cardiomyocytes
    • M. Hagenmueller, J.H. Riffel, E. Bernhold, J. Fan, M. Zhang, M. Ochs, and et al. Dapper-1 induces myocardial remodeling through activation of canonical Wnt signaling in cardiomyocytes Hypertension 61 2013 1177 1183
    • (2013) Hypertension , vol.61 , pp. 1177-1183
    • Hagenmueller, M.1    Riffel, J.H.2    Bernhold, E.3    Fan, J.4    Zhang, M.5    Ochs, M.6
  • 101
    • 84921539288 scopus 로고    scopus 로고
    • Calcium/calmodulin-dependent protein kinase II couples Wnt signaling with histone deacetylase 4 and mediates dishevelled-induced cardiomyopathy
    • M. Zhang, M. Hagenmueller, J.H. Riffel, M.M. Kreusser, E. Bernhold, J. Fan, and et al. Calcium/calmodulin-dependent protein kinase II couples Wnt signaling with histone deacetylase 4 and mediates dishevelled-induced cardiomyopathy Hypertension 65 2015 335 344
    • (2015) Hypertension , vol.65 , pp. 335-344
    • Zhang, M.1    Hagenmueller, M.2    Riffel, J.H.3    Kreusser, M.M.4    Bernhold, E.5    Fan, J.6
  • 102
    • 84863026962 scopus 로고    scopus 로고
    • Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model
    • J.X. Chen, H. Zeng, J. Reese, J.L. Aschner, and B. Meyrick Overexpression of angiopoietin-2 impairs myocardial angiogenesis and exacerbates cardiac fibrosis in the diabetic db/db mouse model Am J Physiol Heart Circ Physiol 302 2012 H1003 H1012
    • (2012) Am J Physiol Heart Circ Physiol , vol.302 , pp. H1003-H1012
    • Chen, J.X.1    Zeng, H.2    Reese, J.3    Aschner, J.L.4    Meyrick, B.5
  • 103
    • 81255209231 scopus 로고    scopus 로고
    • Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy
    • D. Li, Y. Liu, M. Maruyama, W. Zhu, H. Chen, W. Zhang, and et al. Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy Hum Mol Genet 20 2011 4582 4596
    • (2011) Hum Mol Genet , vol.20 , pp. 4582-4596
    • Li, D.1    Liu, Y.2    Maruyama, M.3    Zhu, W.4    Chen, H.5    Zhang, W.6
  • 105
    • 66149101609 scopus 로고    scopus 로고
    • Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy
    • R. Lombardi, J. Dong, G. Rodriguez, A. Bell, T.K. Leung, R.J. Schwartz, and et al. Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy Circ Res 104 2009 1076 1084
    • (2009) Circ Res , vol.104 , pp. 1076-1084
    • Lombardi, R.1    Dong, J.2    Rodriguez, G.3    Bell, A.4    Leung, T.K.5    Schwartz, R.J.6
  • 106
    • 84896589822 scopus 로고    scopus 로고
    • Osmotic drug delivery to ischemic hindlimbs and perfusion of vasculature with microfil for micro-computed tomography imaging
    • X. Liu, T. Terry, S. Pan, Z. Yang, J.T. Willerson, R.A. Dixon, and et al. Osmotic drug delivery to ischemic hindlimbs and perfusion of vasculature with microfil for micro-computed tomography imaging J Vis Exp 2013
    • (2013) J Vis Exp
    • Liu, X.1    Terry, T.2    Pan, S.3    Yang, Z.4    Willerson, J.T.5    Dixon, R.A.6
  • 108
    • 57749105327 scopus 로고    scopus 로고
    • Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector
    • Y.C. Kim, R.J. Clark, E.A. Ranheim, and C.M. Alexander Wnt1 expression induces short-range and long-range cell recruitments that modify mammary tumor development and are not induced by a cell-autonomous beta-catenin effector Cancer Res 68 2008 10145 10153
    • (2008) Cancer Res , vol.68 , pp. 10145-10153
    • Kim, Y.C.1    Clark, R.J.2    Ranheim, E.A.3    Alexander, C.M.4
  • 109
    • 84922513586 scopus 로고    scopus 로고
    • Akt1 signaling coordinates BMP signaling and beta-catenin activity to regulate second heart field progenitor development
    • W. Luo, X. Zhao, H. Jin, L. Tao, J. Zhu, H. Wang, and et al. Akt1 signaling coordinates BMP signaling and beta-catenin activity to regulate second heart field progenitor development Development 142 2015 732 742
    • (2015) Development , vol.142 , pp. 732-742
    • Luo, W.1    Zhao, X.2    Jin, H.3    Tao, L.4    Zhu, J.5    Wang, H.6
  • 110
    • 84928808938 scopus 로고    scopus 로고
    • Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease
    • K. Maiese Novel applications of trophic factors, Wnt and WISP for neuronal repair and regeneration in metabolic disease Neural Regen Res 10 2015 518 528
    • (2015) Neural Regen Res , vol.10 , pp. 518-528
    • Maiese, K.1
  • 112
    • 84949115392 scopus 로고    scopus 로고
    • Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction
    • Y. Lecarpentier, V. Claes, G. Duthoit, and J.L. Hebert Circadian rhythms, Wnt/beta-catenin pathway and PPAR alpha/gamma profiles in diseases with primary or secondary cardiac dysfunction Front Physiol 5 2014 429
    • (2014) Front Physiol , vol.5 , pp. 429
    • Lecarpentier, Y.1    Claes, V.2    Duthoit, G.3    Hebert, J.L.4
  • 113
    • 84871994794 scopus 로고    scopus 로고
    • Knockdown of dishevelled-1 attenuates cyclosporine A-induced apoptosis in H9c2 cardiomyoblast cells
    • Y. Zhu, J. Chi, Y. Liu, Y. Sun, Y. Fu, X. Zhang, and et al. Knockdown of dishevelled-1 attenuates cyclosporine A-induced apoptosis in H9c2 cardiomyoblast cells Mol Cell Biochem 374 2013 113 123
    • (2013) Mol Cell Biochem , vol.374 , pp. 113-123
    • Zhu, Y.1    Chi, J.2    Liu, Y.3    Sun, Y.4    Fu, Y.5    Zhang, X.6
  • 114
    • 78650169897 scopus 로고    scopus 로고
    • Global gene expression profiles of MT knockout and wild-type mice in the condition of doxorubicin-induced cardiomyopathy
    • Y. Shuai, J. Guo, Y. Dong, W. Zhong, P. Xiao, T. Zhou, and et al. Global gene expression profiles of MT knockout and wild-type mice in the condition of doxorubicin-induced cardiomyopathy Toxicol Lett 200 2011 77 87
    • (2011) Toxicol Lett , vol.200 , pp. 77-87
    • Shuai, Y.1    Guo, J.2    Dong, Y.3    Zhong, W.4    Xiao, P.5    Zhou, T.6


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