Acute activation of β2-adrenergic receptor regulates focal adhesions through βArrestin2- and p115RhoGEF protein-mediated activation of RhoA

Journal of Biological Chemistry

Volumn 287, Issue 23, 2012, Pages 18925-18936

  Ma, Xiaojie ^a   Zhao, Yu ^a   Daaka, Yehia ^a   Nie, Zhongzhen ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENERGIC RECEPTORS; CANCER CELLS; CELL MIGRATION; CELLULAR FUNCTION; CONVERGENCE POINTS; COUPLED RECEPTORS; CYTOSOLS; FOCAL ADHESIONS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; P115RHOGEF; PROTEIN COUPLED RECEPTORS; RESTING CELLS; STRESS FIBERS; UNDERLYING MECHANISM;

CELL MEMBRANES; ENZYME INHIBITION; PROTEINS;

ADHESION;

BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN 2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; P115RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL MIGRATION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOSOL; FOCAL ADHESION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STRESS FIBER;

ANIMALS; ARRESTINS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL MOVEMENT; ENZYME ACTIVATION; FOCAL ADHESIONS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HEK293 CELLS; HUMANS; MICE; RECEPTORS, ADRENERGIC, BETA-2; RHO GTP-BINDING PROTEINS; RHOA GTP-BINDING PROTEIN; SIGNAL TRANSDUCTION;

EID: 84861740318     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.352260     Document Type: Article

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