PAR2-dependent activation of GSK3β regulates the survival of colon stem/progenitor cells

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 311, Issue 2, 2016, Pages G221-G236

  Nasri, Imen ^a,b   Bonnet, Delphine ^a,c   Zwarycz, Bailey ^d   D’Aldebert, Emilie ^a   Khou, Sokchea ^a   Mezghani Jarraya, Raoudha ^b   Quaranta, Muriel ^a   Rolland, Corinne ^a   Bonnart, Chrystelle ^a   Mas, Emmanuel ^a,e   Ferrand, Audrey ^a   Cenac, Nicolas ^a   Magness, Scott ^d   van Landeghem, Laurianne ^f   Vergnolle, Nathalie ^a   Racaud Sultan, Claire ^a  

^a UMR 1220 TCEM (INRA ENITAB)   (France)

^b University of Sfax   (Tunisia)

^c CHU PURPAN   (France)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e HÔPITAL DES ENFANTS   (France)

^f UNIVERSITÉ DE NANTES   (France)

Author keywords

Colorectal cancer; Glycogen synthase kinase 3 ; Inflammation; Protease activated receptor; Spheroid

Indexed keywords

CASPASE 3; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; RETINA S ANTIGEN; RHO KINASE; SERINE; GSK3B PROTEIN, HUMAN; GSK3B PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CACO 2 CELL LINE; CELL PROLIFERATION; CELL SURVIVAL; CELLULAR STRESS RESPONSE; COLON CELL; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; INTESTINAL STEM CELL; INTESTINE CRYPT; INTESTINE EPITHELIUM CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DEPLETION; STARVATION; TUMOR CELL; TUMOR SPHEROID; ANIMAL; C57BL MOUSE; CACO-2 CELL LINE; CANCER STEM CELL; COLON; ENZYMOLOGY; EPITHELIUM CELL; GENETIC TRANSFECTION; GENETICS; METABOLISM; MULTICELLULAR SPHEROID; PATHOLOGY; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEM CELL; STEM CELL NICHE; TUMOR MICROENVIRONMENT;

ANIMALS; ARRESTIN; CACO-2 CELLS; CELL PROLIFERATION; CELL SURVIVAL; COLON; ENZYME ACTIVATION; EPITHELIAL CELLS; GLYCOGEN SYNTHASE KINASE 3 BETA; HUMANS; MALE; MICE, INBRED C57BL; NEOPLASTIC STEM CELLS; PHOSPHORYLATION; PROTEIN PHOSPHATASE 2; RECEPTOR, PAR-2; RHO-ASSOCIATED KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SPHEROIDS, CELLULAR; STEM CELL NICHE; STEM CELLS; TRANSFECTION; TUMOR MICROENVIRONMENT;

EID: 84984596161     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00328.2015     Document Type: Article

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