β-arrestin 1 couples thrombin to the rapid activation of the Akt pathway

Annals of the New York Academy of Sciences

Volumn 973, Issue , 2002, Pages 138-141

  Goel, Reema ^a   Baldassare, Joseph J ^a  

^a SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Akt pathway; thrombin; arrestin 1

Indexed keywords

BETA ARRESTIN; PROTEIN KINASE B; RECEPTOR PROTEIN; THROMBIN;

CELL CYCLE G1 PHASE; CELL STRAIN; CLINICAL PATHWAY; CONFERENCE PAPER; DATA ANALYSIS; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; HAMSTER; NONHUMAN; PROTEIN FOLDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

CRICETINAE; CRICETULUS GRISEUS;

EID: 0036962405     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2002.tb04622.x     Document Type: Conference Paper

References (5)

1. KOCH, W.J., J. INGLESE, W.C. STONE & R.J. LEFKOWITZ. 1993. The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J. Biol. Chem. 268: 8256-8260.
2. PHILLIPS-MASON, P.J., D.M. RABEN & J.J. BALDASSARE. 2000. Phosphatidylinositol 3-kinase activity regulates alpha-thrombin-stimulated G(1) progression by its effect on cyclin D1 expression and cyclin-dependent kinase 4 activity. J. Biol. Chem. 275: 18046-18053.
3. WEBER, J.D., D.M. RABEN, P.J. PHILLIPS & J.J. BALDASSARE. 1997. Sustained activation of extracellular-signal-regulated kinase 1(ERK1) is required for the continued expression of cyclin D1 in G1 phase. Biochem. J. 326: 61-68.
4. FERGUSON, S.S., W.E. DOWNEY III, A.M. COLAPIETRO, et al. 1996. Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization. Science 271: 363-366.
5. LUTTRELL, L.M., S.S. FERGUSON, Y. DAAKA, et al. 1999. Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes. Science 283: 655-661.