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Volumn 291, Issue 14, 2016, Pages 7450-7464

Ubiquitin-specific protease 20 regulates the reciprocal functions of β- Arrestin2 in toll-like receptor 4-promoted nuclear factor kB (NFkB) activation

Author keywords

[No Author keywords available]

Indexed keywords

ASSOCIATION REACTIONS; CELLS; CHEMICAL ACTIVATION; DISEASES; MUSCLE; PLANTS (BOTANY);

EID: 84965169006     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.687129     Document Type: Article
Times cited : (41)

References (69)
  • 2
    • 84879118132 scopus 로고    scopus 로고
    • Arrestins come of age: A personal historical perspective
    • Lefkowitz, R. J. (2013) Arrestins come of age: A personal historical perspective. Prog. Mol. Biol. Transl. Sci. 118, 3-18.
    • (2013) Prog. Mol. Biol. Transl. Sci. , vol.118 , pp. 3-18
    • Lefkowitz, R.J.1
  • 3
    • 33751533776 scopus 로고    scopus 로고
    • New roles for - Arrestins in cell signaling: Not just for seven- Transmembrane receptors
    • Lefkowitz, R. J., Rajagopal, K., and Whalen, E. J. (2006) New roles for - Arrestins in cell signaling: Not just for seven- Transmembrane receptors. Mol. Cell 24, 643-652.
    • (2006) Mol. Cell , vol.24 , pp. 643-652
    • Lefkowitz, R.J.1    Rajagopal, K.2    Whalen, E.J.3
  • 4
    • 80052038573 scopus 로고    scopus 로고
    • Arrestin-mediated receptor trafficking and signal transduction
    • Shenoy, S. K., and Lefkowitz, R. J. (2011) -Arrestin-mediated receptor trafficking and signal transduction. Trends Pharmacol. Sci. 32, 521-533.
    • (2011) Trends Pharmacol. Sci , vol.32 , pp. 521-533
    • Shenoy, S.K.1    Lefkowitz, R.J.2
  • 6
    • 31344463886 scopus 로고    scopus 로고
    • Association of - Arrestin and TRAF6 negatively regulates Toll-like receptorinterleukin 1 receptor signaling
    • Wang, Y., Tang, Y., Teng, L., Wu, Y., Zhao, X., and Pei, G. (2006) Association of - Arrestin and TRAF6 negatively regulates Toll-like receptorinterleukin 1 receptor signaling. Nat. Immunol. 7, 139-147.
    • (2006) Nat. Immunol , vol.7 , pp. 139-147
    • Wang, Y.1    Tang, Y.2    Teng, L.3    Wu, Y.4    Zhao, X.5    Pei, G.6
  • 7
    • 2342510314 scopus 로고    scopus 로고
    • Identification of - Arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-B pathways
    • Gao, H., Sun, Y., Wu, Y., Luan, B., Wang, Y., Qu, B., and Pei, G. (2004) Identification of - Arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-B pathways. Mol. Cell 14, 303-317.
    • (2004) Mol. Cell , vol.14 , pp. 303-317
    • Gao, H.1    Sun, Y.2    Wu, Y.3    Luan, B.4    Wang, Y.5    Qu, B.6    Pei, G.7
  • 8
    • 2942554958 scopus 로고    scopus 로고
    • Arrestin inhibits NF-B activity by means of its interaction with the NF-B inhibitor I-B
    • Witherow, D. S., Garrison, T. R., Miller, W. E., and Lefkowitz, R. J. (2004) -Arrestin inhibits NF-B activity by means of its interaction with the NF-B inhibitor I-B-. Proc. Natl. Acad. Sci. U.S.A. 101, 8603-8607.
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 8603-8607
    • Witherow, D.S.1    Garrison, T.R.2    Miller, W.E.3    Lefkowitz, R.J.4
  • 9
    • 84863338304 scopus 로고    scopus 로고
    • Ubiquitination in signaling to and activation of IKK
    • Chen, Z. J. (2012) Ubiquitination in signaling to and activation of IKK. Immunol. Rev. 246, 95-106.
    • (2012) Immunol. Rev. , vol.246 , pp. 95-106
    • Chen, Z.J.1
  • 10
    • 67650744586 scopus 로고    scopus 로고
    • The role of ubiquitin in NF-B regulatory pathways
    • Skaug, B., Jiang, X., and Chen, Z. J. (2009) The role of ubiquitin in NF-B regulatory pathways. Annu. Rev. Biochem. 78, 769-796.
    • (2009) Annu. Rev. Biochem , vol.78 , pp. 769-796
    • Skaug, B.1    Jiang, X.2    Chen, Z.J.3
  • 12
    • 34247280398 scopus 로고    scopus 로고
    • Arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression
    • Fan, H., Luttrell, L. M., Tempel, G. E., Senn, J. J., Halushka, P. V., and Cook, J. A. (2007) -Arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression. Mol. Immunol. 44, 3092-3099.
    • (2007) Mol. Immunol. , vol.44 , pp. 3092-3099
    • Fan, H.1    Luttrell, L.M.2    Tempel, G.E.3    Senn, J.J.4    Halushka, P.V.5    Cook, J.A.6
  • 13
    • 82455210857 scopus 로고    scopus 로고
    • Increased expression of - Arrestin 1 and 2 in murine models of rheumatoid arthritis: Isoform specific regulation of inflammation
    • Li, P., Cook, J. A., Gilkeson, G. S., Luttrell, L. M., Wang, L., Borg, K. T., Halushka, P. V., and Fan, H. (2011) Increased expression of - Arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation. Mol. Immunol. 49, 64-74.
    • (2011) Mol. Immunol , vol.49 , pp. 64-74
    • Li, P.1    Cook, J.A.2    Gilkeson, G.S.3    Luttrell, L.M.4    Wang, L.5    Borg, K.T.6    Halushka, P.V.7    Fan, H.8
  • 14
    • 48049101191 scopus 로고    scopus 로고
    • Arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration
    • -
    • Kim, J., Zhang, L., Peppel, K., Wu, J. H., Zidar, D. A., Brian, L., DeWire, S. M., Exum, S. T., Lefkowitz, R. J., and Freedman, N. J. (2008) -Arrestins regulate atherosclerosis and neointimal hyperplasia by controlling smooth muscle cell proliferation and migration. Circ. Res. 103, 70-79.
    • (2008) Circ. Res , vol.103 , pp. 70-79
    • Kim, J.1    Zhang, L.2    Peppel, K.3    Wu, J.H.4    Zidar, D.A.5    Brian, L.6    DeWire, S.M.7    Exum, S.T.8    Lefkowitz, R.J.9    Freedman, N.J.10
  • 17
    • 14944378649 scopus 로고    scopus 로고
    • Inflammatory mediators in atherosclerotic vascular disease
    • Zernecke, A., and Weber, C. (2005) Inflammatory mediators in atherosclerotic vascular disease. Basic Res. Cardiol. 100, 93-101.
    • (2005) Basic Res. Cardiol , vol.100 , pp. 93-101
    • Zernecke, A.1    Weber, C.2
  • 19
    • 3242710174 scopus 로고    scopus 로고
    • Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E
    • Michelsen, K. S., Wong, M. H., Shah, P. K., Zhang, W., Yano, J., Doherty, T. M., Akira, S., RaJavashisth, T. B., and Arditi, M. (2004) Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E. Proc. Natl. Acad. Sci. U.S.A. 101, 10679-10684.
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 10679-10684
    • Michelsen, K.S.1    Wong, M.H.2    Shah, P.K.3    Zhang, W.4    Yano, J.5    Doherty, T.M.6    Akira, S.7    RaJavashisth, T.B.8    Arditi, M.9
  • 20
    • 84865485915 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. (2012) Inflammation in atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 32, 2045-2051.
    • (2012) Arterioscler. Thromb. Vasc. Biol , vol.32 , pp. 2045-2051
    • Libby, P.1
  • 21
    • 55949084354 scopus 로고    scopus 로고
    • Arrestin 2 is required for lysophosphatidic acid-induced NF-B activation
    • Sun, J., and Lin, X. (2008) -Arrestin 2 is required for lysophosphatidic acid-induced NF-B activation. Proc. Natl. Acad. Sci. U.S.A. 105, 17085-17090.
    • (2008) Proc. Natl. Acad. Sci. U.S.A , vol.105 , pp. 17085-17090
    • Sun, J.1    Lin, X.2
  • 23
    • 66149116039 scopus 로고    scopus 로고
    • Arrestin-dependent signaling and trafficking of 7- Transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2
    • -
    • Shenoy, S. K., Modi, A. S., Shukla, A. K., Xiao, K., Berthouze, M., Ahn, S., Wilkinson, K. D., Miller, W. E., and Lefkowitz, R. J. (2009) -Arrestin-dependent signaling and trafficking of 7- Transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proc. Natl. Acad. Sci. U.S.A. 106, 6650-6655.
    • (2009) Proc. Natl. Acad. Sci. U.S.A. , vol.106 , pp. 6650-6655
    • Shenoy, S.K.1    Modi, A.S.2    Shukla, A.K.3    Xiao, K.4    Berthouze, M.5    Ahn, S.6    Wilkinson, K.D.7    Miller, W.E.8    Lefkowitz, R.J.9
  • 24
    • 80052049291 scopus 로고    scopus 로고
    • Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-B signaling
    • Yasunaga, J., Lin, F. C., Lu, X., and Jeang, K. T. (2011) Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-B signaling. J. Virol. 85, 6212-6219.
    • (2011) J. Virol , vol.85 , pp. 6212-6219
    • Yasunaga, J.1    Lin, F.C.2    Lu, X.3    Jeang, K.T.4
  • 25
    • 67649556158 scopus 로고    scopus 로고
    • The deubiquitinases USP33 and USP20 coordinate -2 adrenergic receptor recycling and resensitization
    • Berthouze, M., Venkataramanan, V., Li, Y., and Shenoy, S. K. (2009) The deubiquitinases USP33 and USP20 coordinate -2 adrenergic receptor recycling and resensitization. EMBO J. 28, 1684-1696.
    • (2009) EMBO J , vol.28 , pp. 1684-1696
    • Berthouze, M.1    Venkataramanan, V.2    Li, Y.3    Shenoy, S.K.4
  • 26
    • 0029164672 scopus 로고
    • Cloning and analysis of the promoter region of the rat SM22 - gene
    • Kemp, P. R., Osbourn, J. K., Grainger, D. J., and Metcalfe, J. C. (1995) Cloning and analysis of the promoter region of the rat SM22 - gene. Biochem. J. 310, 1037-1043.
    • (1995) Biochem. J , vol.310 , pp. 1037-1043
    • Kemp, P.R.1    Osbourn, J.K.2    Grainger, D.J.3    Metcalfe, J.C.4
  • 27
    • 0028939406 scopus 로고
    • A regulatory element downstream of the rat SM22 - gene transcription start point enhances reporter gene expression in vascular smooth muscle cells
    • Osbourn, J. K., Weissberg, P. L., and Shanahan, C. M. (1995) A regulatory element downstream of the rat SM22 - gene transcription start point enhances reporter gene expression in vascular smooth muscle cells. Gene 154, 249-253.
    • (1995) Gene , vol.154 , pp. 249-253
    • Osbourn, J.K.1    Weissberg, P.L.2    Shanahan, C.M.3
  • 28
    • 24044537898 scopus 로고    scopus 로고
    • Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling
    • Keys, J. R., Zhou, R. H., Harris, D. M., Druckman, C. A., and Eckhart, A. D. (2005) Vascular smooth muscle overexpression of G protein-coupled receptor kinase 5 elevates blood pressure, which segregates with sex and is dependent on Gi-mediated signaling. Circulation 112, 1145-1153.
    • (2005) Circulation , vol.112 , pp. 1145-1153
    • Keys, J.R.1    Zhou, R.H.2    Harris, D.M.3    Druckman, C.A.4    Eckhart, A.D.5
  • 29
    • 0035852697 scopus 로고    scopus 로고
    • Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
    • -
    • Kohout, T. A., Lin, F. S., Perry, S. J., Conner, D. A., and Lefkowitz, R. J. (2001) -Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking. Proc. Natl. Acad. Sci. U.S.A. 98, 1601-1606.
    • (2001) Proc. Natl. Acad. Sci. U.S.A , vol.98 , pp. 1601-1606
    • Kohout, T.A.1    Lin, F.S.2    Perry, S.J.3    Conner, D.A.4    Lefkowitz, R.J.5
  • 30
    • 11244311659 scopus 로고    scopus 로고
    • Activationdependent conformational changes in - Arrestin 2
    • Xiao, K., Shenoy, S. K., Nobles, K., and Lefkowitz, R. J. (2004) Activationdependent conformational changes in - Arrestin 2. J. Biol. Chem. 279, 55744-55753.
    • (2004) J. Biol. Chem , vol.279 , pp. 55744-55753
    • Xiao, K.1    Shenoy, S.K.2    Nobles, K.3    Lefkowitz, R.J.4
  • 32
    • 62149129361 scopus 로고    scopus 로고
    • Reciprocal regulation of the plateletderived growth factor receptor- AndGprotein-coupled receptor kinase 5 by cross-phosphorylation: Effects on catalysis
    • Cai, X., Wu, J. H., Exum, S. T., Oppermann, M., Premont, R. T., Shenoy, S. K., and Freedman, N. J. (2009) Reciprocal regulation of the plateletderived growth factor receptor- AndGprotein-coupled receptor kinase 5 by cross-phosphorylation: Effects on catalysis. Mol. Pharmacol. 75, 626-636.
    • (2009) Mol. Pharmacol , vol.75 , pp. 626-636
    • Cai, X.1    Wu, J.H.2    Exum, S.T.3    Oppermann, M.4    Premont, R.T.5    Shenoy, S.K.6    Freedman, N.J.7
  • 33
    • 0035834428 scopus 로고    scopus 로고
    • Regulation of receptor fate by ubiquitination of activated - 2- Adrenergic receptor and - Arrestin
    • Shenoy, S. K., McDonald, P. H., Kohout, T. A., and Lefkowitz, R. J. (2001) Regulation of receptor fate by ubiquitination of activated - 2- Adrenergic receptor and - Arrestin. Science 294, 1307-1313.
    • (2001) Science , vol.294 , pp. 1307-1313
    • Shenoy, S.K.1    McDonald, P.H.2    Kohout, T.A.3    Lefkowitz, R.J.4
  • 36
    • 84871997357 scopus 로고    scopus 로고
    • MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound -(2)- Adrenergic receptors
    • Han, S. O., Xiao, K., Kim, J., Wu, J. H., Wisler, J. W., Nakamura, N., Freedman, N. J., and Shenoy, S. K. (2012) MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound -(2)- Adrenergic receptors. J. Cell Biol. 199, 817-830.
    • (2012) J. Cell Biol , vol.199 , pp. 817-830
    • Han, S.O.1    Xiao, K.2    Kim, J.3    Wu, J.H.4    Wisler, J.W.5    Nakamura, N.6    Freedman, N.J.7    Shenoy, S.K.8
  • 37
    • 84873411358 scopus 로고    scopus 로고
    • Distinct roles for - Arrestin2 and arrestin-domain-containing proteins in -2 adrenergic re-ceptor trafficking
    • Han, S. O., Kommaddi, R. P., and Shenoy, S. K. (2013) Distinct roles for - Arrestin2 and arrestin-domain-containing proteins in -2 adrenergic re-ceptor trafficking. EMBO Rep. 14, 164-171.
    • (2013) EMBO Rep. , vol.14 , pp. 164-171
    • Han, S.O.1    Kommaddi, R.P.2    Shenoy, S.K.3
  • 38
    • 84879088145 scopus 로고    scopus 로고
    • Arrestins as regulators of kinases and phosphatases
    • Luttrell, L. M., and Miller, W. E. (2013) Arrestins as regulators of kinases and phosphatases. Prog. Mol. Biol. Transl. Sci. 118, 115-147.
    • (2013) Prog. Mol. Biol. Transl. Sci. , vol.118 , pp. 115-147
    • Luttrell, L.M.1    Miller, W.E.2
  • 39
    • 84890157678 scopus 로고    scopus 로고
    • Role of - Arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking
    • Kang, D. S., Tian, X., and Benovic, J. L. (2014) Role of - Arrestins and arrestin domain-containing proteins in G protein-coupled receptor trafficking. Curr. Opin. Cell Biol. 27, 63-71.
    • (2014) Curr. Opin. Cell Biol , vol.27 , pp. 63-71
    • Kang, D.S.1    Tian, X.2    Benovic, J.L.3
  • 40
    • 0029670058 scopus 로고    scopus 로고
    • Expression of the SM22- promoter in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells
    • Li, L., Miano, J. M., Mercer, B., and Olson, E. N. (1996) Expression of the SM22- promoter in transgenic mice provides evidence for distinct transcriptional regulatory programs in vascular and visceral smooth muscle cells. J. Cell Biol. 132, 849-859.
    • (1996) J. Cell Biol , vol.132 , pp. 849-859
    • Li, L.1    Miano, J.M.2    Mercer, B.3    Olson, E.N.4
  • 43
    • 33748549007 scopus 로고    scopus 로고
    • Mouse models of neointimal hyperplasia: Techniques and applications
    • Wang, X., Chai, H., Lin, P. H., Lumsden, A. B., Yao, Q., and Chen, C. (2006) Mouse models of neointimal hyperplasia: Techniques and applications. Med. Sci. Monit. 12, RA177- RA185.
    • (2006) Med. Sci. Monit , vol.12 , pp. RA177-RA185
    • Wang, X.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 44
    • 0141703513 scopus 로고    scopus 로고
    • Tumor necrosis factor-induced IKK phosphorylation of NF-B p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway
    • Sakurai, H., Suzuki, S., Kawasaki, N., Nakano, H., Okazaki, T., Chino, A., Doi, T., and Saiki, I. (2003) Tumor necrosis factor-induced IKK phosphorylation of NF-B p65 on serine 536 is mediated through the TRAF2, TRAF5, and TAK1 signaling pathway. J. Biol. Chem. 278, 36916-36923.
    • (2003) J. Biol. Chem , vol.278 , pp. 36916-36923
    • Sakurai, H.1    Suzuki, S.2    Kawasaki, N.3    Nakano, H.4    Okazaki, T.5    Chino, A.6    Doi, T.7    Saiki, I.8
  • 45
    • 0037851769 scopus 로고    scopus 로고
    • IKK - plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide
    • Yang, F., Tang, E., Guan, K., and Wang, C. Y. (2003) IKK - plays an essential role in the phosphorylation of RelA/p65 on serine 536 induced by lipopolysaccharide. J. Immunol. 170, 5630-5635.
    • (2003) J. Immunol , vol.170 , pp. 5630-5635
    • Yang, F.1    Tang, E.2    Guan, K.3    Wang, C.Y.4
  • 46
    • 0036781052 scopus 로고    scopus 로고
    • NF-B regulation in the immune system
    • Li, Q., and Verma, I. M. (2002) NF-B regulation in the immune system. Nat. Rev. Immunol. 2, 725-734.
    • (2002) Nat. Rev. Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 47
    • 0026490278 scopus 로고
    • Functional analysis of the human vascular cell adhesion molecule 1 promoter
    • Neish, A. S., Williams, A. J., Palmer, H. J., Whitley, M. Z., and Collins, T. (1992) Functional analysis of the human vascular cell adhesion molecule 1 promoter. J. Exp. Med. 176, 1583-1593.
    • (1992) J. Exp. Med , vol.176 , pp. 1583-1593
    • Neish, A.S.1    Williams, A.J.2    Palmer, H.J.3    Whitley, M.Z.4    Collins, T.5
  • 48
    • 81055143970 scopus 로고    scopus 로고
    • PPAR- Attenuates intimal hyperplasia by inhibiting TLR4-mediated inflammation in vascular smooth muscle cells
    • Zhang, L. L., Gao, C. Y., Fang, C. Q., Wang, Y. J., Gao, D., Yao, G. E., Xiang, J., Wang, J. Z., and Li, J. C. (2011) PPAR- Attenuates intimal hyperplasia by inhibiting TLR4-mediated inflammation in vascular smooth muscle cells. Cardiovasc. Res. 92, 484-493.
    • (2011) Cardiovasc. Res , vol.92 , pp. 484-493
    • Zhang, L.L.1    Gao, C.Y.2    Fang, C.Q.3    Wang, Y.J.4    Gao, D.5    Yao, G.E.6    Xiang, J.7    Wang, J.Z.8    Li, J.C.9
  • 49
    • 33750537650 scopus 로고    scopus 로고
    • Endotoxin, TLR4 signaling and vascular inflammation: Potential therapeutic targets in cardiovascular disease
    • Stoll, L. L., Denning, G. M., and Weintraub, N. L. (2006) Endotoxin, TLR4 signaling and vascular inflammation: Potential therapeutic targets in cardiovascular disease. Curr. Pharm. Des. 12, 4229-4245.
    • (2006) Curr. Pharm. des , vol.12 , pp. 4229-4245
    • Stoll, L.L.1    Denning, G.M.2    Weintraub, N.L.3
  • 50
    • 0037737763 scopus 로고    scopus 로고
    • Trafficking patterns of- Arrestin and G protein-coupled receptors determined by the kinetics of - Arrestin deubiquitination
    • Shenoy, S. K., and Lefkowitz, R. J. (2003) Trafficking patterns of- Arrestin and G protein-coupled receptors determined by the kinetics of - Arrestin deubiquitination. J. Biol. Chem. 278, 14498-14506.
    • (2003) J. Biol. Chem. , vol.278 , pp. 14498-14506
    • Shenoy, S.K.1    Lefkowitz, R.J.2
  • 51
    • 50949126350 scopus 로고    scopus 로고
    • Protein partners of deubiquitinating enzymes
    • Ventii, K. H., and Wilkinson, K. D. (2008) Protein partners of deubiquitinating enzymes. Biochem. J. 414, 161-175.
    • (2008) Biochem. J , vol.414 , pp. 161-175
    • Ventii, K.H.1    Wilkinson, K.D.2
  • 52
    • 2442429603 scopus 로고    scopus 로고
    • Tumor necrosis factor - Activates the human plasminogen activator inhibitor-1 gene through a distal nuclear factor -B site
    • Hou, B., Eren, M., Painter, C. A., Covington, J. W., Dixon, J. D., Schoenhard, J. A., and Vaughan, D. E. (2004) Tumor necrosis factor - Activates the human plasminogen activator inhibitor-1 gene through a distal nuclear factor -B site. J. Biol. Chem. 279, 18127-18136.
    • (2004) J. Biol. Chem , vol.279 , pp. 18127-18136
    • Hou, B.1    Eren, M.2    Painter, C.A.3    Covington, J.W.4    Dixon, J.D.5    Schoenhard, J.A.6    Vaughan, D.E.7
  • 54
    • 84866742560 scopus 로고    scopus 로고
    • TGF- signalling in context
    • Massagué, J. (2012) TGF- signalling in context. Nat. Rev. Mol. Cell Biol. 13, 616-630.
    • (2012) Nat. Rev. Mol. Cell Biol , vol.13 , pp. 616-630
    • Massagué, J.1
  • 55
    • 23144449789 scopus 로고    scopus 로고
    • Ubiquitin signalling in the NF-B pathway
    • Chen, Z. J. (2005) Ubiquitin signalling in the NF-B pathway. Nat. Cell Biol. 7, 758-765.
    • (2005) Nat. Cell Biol , vol.7 , pp. 758-765
    • Chen, Z.J.1
  • 56
    • 33748947656 scopus 로고    scopus 로고
    • The UL144 gene product of human cytomegalovirus activates NF-B via a TRAF6-dependent mechanism
    • Poole, E., King, C. A., Sinclair, J. H., and Alcami, A. (2006) The UL144 gene product of human cytomegalovirus activates NF-B via a TRAF6-dependent mechanism. EMBO J. 25, 4390-4399.
    • (2006) EMBO J , vol.25 , pp. 4390-4399
    • Poole, E.1    King, C.A.2    Sinclair, J.H.3    Alcami, A.4
  • 58
    • 84858119736 scopus 로고    scopus 로고
    • Cellular functions of the DUBs
    • Clague, M. J., Coulson, J. M., and Urbé, S. (2012) Cellular functions of the DUBs. J. Cell Sci. 125, 277-286.
    • (2012) J. Cell Sci , vol.125 , pp. 277-286
    • Clague, M.J.1    Coulson, J.M.2    Urbé, S.3
  • 60
    • 78650915537 scopus 로고    scopus 로고
    • Deubiquitinases in the regulation of NF-B signaling
    • Harhaj, E. W., and Dixit, V. M. (2011) Deubiquitinases in the regulation of NF-B signaling. Cell Res 21, 22-39.
    • (2011) Cell Res , vol.21 , pp. 22-39
    • Harhaj, E.W.1    Dixit, V.M.2
  • 61
    • 33750598021 scopus 로고    scopus 로고
    • Impaired regulation of NF-B and increased susceptibility to colitis- Associated tumorigenesis in CYLD-deficient mice
    • Zhang, J., Stirling, B., Temmerman, S. T., Ma, C. A., Fuss, I. J., Derry, J. M., and Jain, A. (2006) Impaired regulation of NF-B and increased susceptibility to colitis- Associated tumorigenesis in CYLD-deficient mice. J. Clin. Invest. 116, 3042-3049.
    • (2006) J. Clin. Invest , vol.116 , pp. 3042-3049
    • Zhang, J.1    Stirling, B.2    Temmerman, S.T.3    Ma, C.A.4    Fuss, I.J.5    Derry, J.M.6    Jain, A.7
  • 62
    • 0034668204 scopus 로고    scopus 로고
    • A20 and A20-binding proteins as cellular inhibitors of nuclear factor- B-dependent gene expression and apoptosis
    • Beyaert, R., Heyninck, K., and Van Huffel, S. (2000) A20 and A20-binding proteins as cellular inhibitors of nuclear factor- B-dependent gene expression and apoptosis. Biochem. Pharmacol. 60, 1143-1151.
    • (2000) Biochem. Pharmacol , vol.60 , pp. 1143-1151
    • Beyaert, R.1    Heyninck, K.2    Van Huffel, S.3
  • 64
    • 84858120447 scopus 로고    scopus 로고
    • Regulation of NF-B signaling by the A20 deubiquitinase
    • Shembade, N., and Harhaj, E. W. (2012) Regulation of NF-B signaling by the A20 deubiquitinase. Cell. Mol. Immunol. 9, 123-130.
    • (2012) Cell, Mol. Immunol , vol.9 , pp. 123-130
    • Shembade, N.1    Harhaj, E.W.2
  • 65
    • 36749057932 scopus 로고    scopus 로고
    • The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-B target genes
    • Wolfrum, S., Teupser, D., Tan, M., Chen, K. Y., and Breslow, J. L. (2007) The protective effect of A20 on atherosclerosis in apolipoprotein E-deficient mice is associated with reduced expression of NF-B target genes. Proc. Natl. Acad. Sci. U.S.A. 104, 18601-18606.
    • (2007) Proc. Natl. Acad. Sci. U.S.A , vol.104 , pp. 18601-18606
    • Wolfrum, S.1    Teupser, D.2    Tan, M.3    Chen, K.Y.4    Breslow, J.L.5
  • 66
    • 84903726513 scopus 로고    scopus 로고
    • The deubiquitinase activity of A20 is dispensable for NF-B signaling
    • De, A., Dainichi, T., Rathinam, C. V., and Ghosh, S. (2014) The deubiquitinase activity of A20 is dispensable for NF-B signaling. EMBO Rep. 15, 775-783.
    • (2014) EMBO Rep , vol.15 , pp. 775-783
    • De, A.1    Dainichi, T.2    Rathinam, C.V.3    Ghosh, S.4
  • 67
    • 84926434294 scopus 로고    scopus 로고
    • Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates postendocytic trafficking of -2 adrenergic receptors to autophagosomes during physiological stress
    • Kommaddi, R. P., Jean-Charles, P. Y., and Shenoy, S. K. (2015) Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates postendocytic trafficking of -2 adrenergic receptors to autophagosomes during physiological stress. J. Biol. Chem. 290, 8888-8903.
    • (2015) J. Biol. Chem , vol.290 , pp. 8888-8903
    • Kommaddi, R.P.1    Jean-Charles, P.Y.2    Shenoy, S.K.3
  • 68
    • 0037292275 scopus 로고    scopus 로고
    • Functional diversity and regulation of different interleukin-1 receptor- Associated kinase (IRAK) family members
    • Janssens, S., and Beyaert, R. (2003) Functional diversity and regulation of different interleukin-1 receptor- Associated kinase (IRAK) family members. Mol. Cell 11, 293-302.
    • (2003) Mol. Cell , vol.11 , pp. 293-302
    • Janssens, S.1    Beyaert, R.2


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