메뉴 건너뛰기




Volumn 116, Issue 2, 2016, Pages 223-246

Reversibility of endothelial dysfunction in diabetes: Role of polyphenols

Author keywords

Cell signalling; Diabetes; Endothelial dysfunction; Polyphenols

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; DIPEPTIDYL PEPTIDASE IV INHIBITOR; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOLIC ACID; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; GLUCOSE; METFORMIN; NITRIC OXIDE; ORGANIC NITRATE; PHOSPHODIESTERASE V INHIBITOR; POLYPHENOL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SODIUM GLUCOSE COTRANSPORTER INHIBITOR; TRANSCRIPTION FACTOR NRF2; VASCULOTROPIN; VITAMIN D; XANTHINE OXIDASE; NITRIC OXIDE SYNTHASE; PLANT EXTRACT; VASCULOTROPIN A;

EID: 84973327581     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114516001884     Document Type: Article
Times cited : (94)

References (262)
  • 1
    • 3242761489 scopus 로고    scopus 로고
    • Physiology of the endothelium
    • Galley HF &Webster NR (2004) Physiology of the endothelium. Br J Anaesth 93, 105-113
    • (2004) Br J Anaesth , vol.93 , pp. 105-113
    • Galley, H.F.1    Webster, N.R.2
  • 2
    • 33745948085 scopus 로고    scopus 로고
    • Insulin resistance and endothelial dysfunction: The road map to cardiovascular diseases
    • Cersosimo E &DeFronzo RA (2006) Insulin resistance and endothelial dysfunction: the road map to cardiovascular diseases. Diabetes Metab Res Rev 22, 423-436
    • (2006) Diabetes Metab Res Rev , vol.22 , pp. 423-436
    • Cersosimo, E.1    DeFronzo, R.A.2
  • 3
    • 33846798106 scopus 로고    scopus 로고
    • Phenotypic heterogeneity of the endothelium: I Structure, function, and mechanisms
    • Aird WC (2007) Phenotypic heterogeneity of the endothelium: I. Structure, function, and mechanisms. Circ Res 100, 158-173
    • (2007) Circ Res , vol.100 , pp. 158-173
    • Aird, W.C.1
  • 4
    • 0025804983 scopus 로고
    • Endothelium-derived relaxing and contracting factors
    • Rubanyi GM (1991) Endothelium-derived relaxing and contracting factors. J Cell Biochem 46, 27-36
    • (1991) J Cell Biochem , vol.46 , pp. 27-36
    • Rubanyi, G.M.1
  • 5
    • 10544239533 scopus 로고    scopus 로고
    • The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation
    • Shimokawa H, Yasutake H, Fujii K, et al. (1996) The importance of the hyperpolarizing mechanism increases as the vessel size decreases in endothelium-dependent relaxations in rat mesenteric circulation. J Cardiovasc Pharmacol 28, 703-711
    • (1996) J Cardiovasc Pharmacol , vol.28 , pp. 703-711
    • Shimokawa, H.1    Yasutake, H.2    Fujii, K.3
  • 6
    • 84892914260 scopus 로고    scopus 로고
    • The vascular endothelium and human diseases
    • Rajendran P, Rengarajan T, Thangavel J, et al. (2013) The vascular endothelium and human diseases. Int J Biol Sci 9, 1057-1069
    • (2013) J Biol Sci , vol.9 , pp. 1057-1069
    • Rajendran, P.1    Rengarajan, T.2    Thangavel, J.3
  • 7
    • 84877139752 scopus 로고    scopus 로고
    • The coagulation system in humans
    • Chan AK &Paredes N (2013) The coagulation system in humans. Methods Mol Biol 992, 3-12
    • (2013) Methods Mol Biol , vol.992 , pp. 3-12
    • Chan, A.K.1    Paredes, N.2
  • 8
    • 0041767435 scopus 로고    scopus 로고
    • Endothelial cell functions
    • Michiels C (2003) Endothelial cell functions. J Cell Physiol 196, 430-443
    • (2003) J Cell Physiol , vol.196 , pp. 430-443
    • Michiels, C.1
  • 9
    • 33845508385 scopus 로고    scopus 로고
    • The pivotal role of the endothelium in haemostasis and thrombosis
    • Verhamme P &Hoylaerts MF (2006) The pivotal role of the endothelium in haemostasis and thrombosis. Acta Clin Belg 61, 213-219
    • (2006) Acta Clin Belg , vol.61 , pp. 213-219
    • Verhamme, P.1    Hoylaerts, M.F.2
  • 10
    • 2342430184 scopus 로고    scopus 로고
    • Vasculogenesis and angiogenesis
    • Patan S (2004) Vasculogenesis and angiogenesis. Cancer Treat Res 117, 3-32
    • (2004) Cancer Treat Res , vol.117 , pp. 3-32
    • Patan, S.1
  • 11
    • 0348049834 scopus 로고    scopus 로고
    • VEGF signalling: Integration and multi-tasking in endothelial cell biology
    • Zachary I (2003) VEGF signalling: integration and multi-tasking in endothelial cell biology. Biochem Soc Trans 31, 1171-1177
    • (2003) Biochem Soc Trans , vol.31 , pp. 1171-1177
    • Zachary, I.1
  • 12
    • 33646107369 scopus 로고    scopus 로고
    • VEGF receptor signalling-in control of vascular function
    • Olsson AK, Dimberg A, Kreuger J, et al. (2006) VEGF receptor signalling-in control of vascular function. Nat Rev Mol Cell Biol 7, 359-371
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 359-371
    • Olsson, A.K.1    Dimberg, A.2    Kreuger, J.3
  • 13
    • 0032773364 scopus 로고    scopus 로고
    • Endothelial function and atherosclerosis
    • Biegelsen ES &Loscalzo J (1999) Endothelial function and atherosclerosis. Coron Artery Dis 10, 241-256
    • (1999) Coron Artery Dis , vol.10 , pp. 241-256
    • Biegelsen, E.S.1    Loscalzo, J.2
  • 14
    • 7244248569 scopus 로고    scopus 로고
    • A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them
    • Carman CV &Springer TA (2004) A transmigratory cup in leukocyte diapedesis both through individual vascular endothelial cells and between them. J Cell Biol 167, 377-388
    • (2004) J Cell Biol , vol.167 , pp. 377-388
    • Carman, C.V.1    Springer, T.A.2
  • 15
    • 0033724749 scopus 로고    scopus 로고
    • Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells
    • Rahman A, Anwar KN &Malik AB (2000) Protein kinase C-zeta mediates TNF-alpha-induced ICAM-1 gene transcription in endothelial cells. Am J Physiol Cell Physiol 279, C906-C914
    • (2000) Am J Physiol Cell Physiol , vol.279 , pp. C906-C914
    • Rahman, A.1    Anwar, K.N.2    Malik, A.B.3
  • 16
    • 58649100256 scopus 로고    scopus 로고
    • Monocyte-endothelial cell interactions in the development of atherosclerosis
    • Mestas J &Ley K (2008) Monocyte-endothelial cell interactions in the development of atherosclerosis. Trends Cardiovasc Med 18, 228-232
    • (2008) Trends Cardiovasc Med , vol.18 , pp. 228-232
    • Mestas, J.1    Ley, K.2
  • 17
    • 0037007153 scopus 로고    scopus 로고
    • Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: A prospective study
    • Gokce N, Keaney JF Jr, Hunter LM, et al. (2002) Risk stratification for postoperative cardiovascular events via noninvasive assessment of endothelial function: a prospective study. Circulation 105, 1567-1572
    • (2002) Circulation , vol.105 , pp. 1567-1572
    • Gokce, N.1    Keaney, J.F.2    Hunter, L.M.3
  • 18
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM &Maseri A (2002) Inflammation and atherosclerosis. Circulation 105, 1135-1143
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 19
    • 84890963093 scopus 로고    scopus 로고
    • Nitric oxide directly promotes vascular endothelial insulin transport
    • Wang H, Wang AX, Aylor K, et al. (2013) Nitric oxide directly promotes vascular endothelial insulin transport. Diabetes 62, 4030-4042
    • (2013) Diabetes , vol.62 , pp. 4030-4042
    • Wang, H.1    Wang, A.X.2    Aylor, K.3
  • 20
    • 27944445736 scopus 로고    scopus 로고
    • Mechanisms of endothelial dysfunction with development of type 1 diabetes mellitus: Role of insulin and C-peptide
    • Joshua IG, Zhang Q, Falcone JC, et al. (2005) Mechanisms of endothelial dysfunction with development of type 1 diabetes mellitus: role of insulin and C-peptide. J Cell Biochem 96, 1149-1156
    • (2005) J Cell Biochem , vol.96 , pp. 1149-1156
    • Joshua, I.G.1    Zhang, Q.2    Falcone, J.C.3
  • 21
    • 34547483879 scopus 로고    scopus 로고
    • Therapeutic regulation of endothelial dysfunction in type 2 diabetes mellitus
    • Hamilton SJ, Chew GT &Watts GF (2007) Therapeutic regulation of endothelial dysfunction in type 2 diabetes mellitus. Diab Vasc Dis Res 4, 89-102
    • (2007) Diab Vasc Dis Res , vol.4 , pp. 89-102
    • Hamilton, S.J.1    Chew, G.T.2    Watts, G.F.3
  • 23
    • 84858315403 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes mellitus: Possible involvement of endoplasmic reticulum stress
    • Basha B, Samuel SM, Triggle CR, et al. (2012) Endothelial dysfunction in diabetes mellitus: possible involvement of endoplasmic reticulum stress? Exp Diabetes Res 2012, 481840
    • (2012) Exp Diabetes Res , vol.2012 , pp. 481840
    • Basha, B.1    Samuel, S.M.2    Triggle, C.R.3
  • 25
    • 38649101592 scopus 로고    scopus 로고
    • Inhibitory effects of fenofibrate on apoptosis and cell proliferation in human endothelial cells in high glucose
    • Zanetti M, Stocca A, Dapas B, et al. (2008) Inhibitory effects of fenofibrate on apoptosis and cell proliferation in human endothelial cells in high glucose. J Mol Med (Berl) 86, 185-195
    • (2008) J Mol Med (Berl) , vol.86 , pp. 185-195
    • Zanetti, M.1    Stocca, A.2    Dapas, B.3
  • 26
    • 70350152746 scopus 로고    scopus 로고
    • Inflammatory stress in primary venous and aortic endothelial cells of type 1 diabetic mice
    • Bucciarelli LG, Pollreisz A, Kebschull M, et al. (2009) Inflammatory stress in primary venous and aortic endothelial cells of type 1 diabetic mice. Diab Vasc Dis Res 6, 249-261
    • (2009) Diab Vasc Dis Res , vol.6 , pp. 249-261
    • Bucciarelli, L.G.1    Pollreisz, A.2    Kebschull, M.3
  • 27
    • 70749083140 scopus 로고    scopus 로고
    • PEDF prevents reactive oxygen species generation and retinal endothelial cell damage at high glucose levels
    • Banumathi E, Sheikpranbabu S, Haribalaganesh R, et al. (2010) PEDF prevents reactive oxygen species generation and retinal endothelial cell damage at high glucose levels. Exp Eye Res 90, 89-96
    • (2010) Exp Eye Res , vol.90 , pp. 89-96
    • Banumathi, E.1    Sheikpranbabu, S.2    Haribalaganesh, R.3
  • 28
    • 54149092601 scopus 로고    scopus 로고
    • Na +/H + exchanger is required for hyperglycaemia-induced endothelial dysfunction via calcium-dependent calpain
    • Wang S, Peng Q, Zhang J, et al. (2008) Na +/H + exchanger is required for hyperglycaemia-induced endothelial dysfunction via calcium-dependent calpain. Cardiovasc Res 80, 255-262
    • (2008) Cardiovasc Res , vol.80 , pp. 255-262
    • Wang, S.1    Peng, Q.2    Zhang, J.3
  • 30
    • 79952142784 scopus 로고    scopus 로고
    • Impaired insulin signaling in endothelial cells reduces insulininduced glucose uptake by skeletal muscle
    • Kubota T, Kubota N, Kumagai H, et al. (2011) Impaired insulin signaling in endothelial cells reduces insulininduced glucose uptake by skeletal muscle. Cell Metab 13, 294-307
    • (2011) Cell Metab , vol.13 , pp. 294-307
    • Kubota, T.1    Kubota, N.2    Kumagai, H.3
  • 31
    • 18244366915 scopus 로고    scopus 로고
    • The union of vascular and metabolic actions of insulin in sickness and in health
    • Kim JA, Koh KK &Quon MJ (2005) The union of vascular and metabolic actions of insulin in sickness and in health. Arterioscler Thromb Vasc Biol 25, 889-891
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 889-891
    • Kim, J.A.1    Koh, K.K.2    Quon, M.J.3
  • 32
    • 70349648329 scopus 로고    scopus 로고
    • Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: The role of endothelin-1
    • Gogg S, Smith U &Jansson PA (2009) Increased MAPK activation and impaired insulin signaling in subcutaneous microvascular endothelial cells in type 2 diabetes: the role of endothelin-1. Diabetes 58, 2238-2245
    • (2009) Diabetes , vol.58 , pp. 2238-2245
    • Gogg, S.1    Smith, U.2    Jansson, P.A.3
  • 33
    • 0037022206 scopus 로고    scopus 로고
    • Insulin causes endothelial dysfunction in humans: Sites and mechanisms
    • Arcaro G, Cretti A, Balzano S, et al. (2002) Insulin causes endothelial dysfunction in humans: sites and mechanisms. Circulation 105, 576-582
    • (2002) Circulation , vol.105 , pp. 576-582
    • Arcaro, G.1    Cretti, A.2    Balzano, S.3
  • 34
    • 50449085395 scopus 로고    scopus 로고
    • An integrated view of insulin resistance and endothelial dysfunction
    • Muniyappa R, Iantorno M &Quon MJ (2008) An integrated view of insulin resistance and endothelial dysfunction. Endocrinol Metab Clin North Am 37, 685-711, ix-x
    • (2008) Endocrinol Metab Clin North Am , vol.37 , pp. 685-711
    • Muniyappa, R.1    Iantorno, M.2    Quon, M.J.3
  • 35
    • 0033968126 scopus 로고    scopus 로고
    • Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle
    • Cusi K, Maezono K, Osman A, et al. (2000) Insulin resistance differentially affects the PI 3-kinase-and MAP kinase-mediated signaling in human muscle. J Clin Invest 105, 311-320
    • (2000) J Clin Invest , vol.105 , pp. 311-320
    • Cusi, K.1    Maezono, K.2    Osman, A.3
  • 36
    • 0034708347 scopus 로고    scopus 로고
    • Endothelin-1 induces NAD(P)H oxidase in human endothelial cells
    • Duerrschmidt N, Wippich N, Goettsch W, et al. (2000) Endothelin-1 induces NAD(P)H oxidase in human endothelial cells. Biochem Biophys Res Commun 269, 713-717
    • (2000) Biochem Biophys Res Commun , vol.269 , pp. 713-717
    • Duerrschmidt, N.1    Wippich, N.2    Goettsch, W.3
  • 37
    • 61949439551 scopus 로고    scopus 로고
    • Endothelial dysfunction in diabetes: From mechanisms to therapeutic targets
    • Potenza MA, Gagliardi S, Nacci C, et al. (2009) Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets. Curr Med Chem 16, 94-112
    • (2009) Curr Med Chem , vol.16 , pp. 94-112
    • Potenza, M.A.1    Gagliardi, S.2    Nacci, C.3
  • 38
    • 57749177096 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: Roles of hyperglycemia, impaired insulin signaling and obesity
    • Bakker W, Eringa EC, Sipkema P, et al. (2009) Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res 335, 165-189
    • (2009) Cell Tissue Res , vol.335 , pp. 165-189
    • Bakker, W.1    Eringa, E.C.2    Sipkema, P.3
  • 39
    • 33751171952 scopus 로고    scopus 로고
    • High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: Role of xanthine oxidase-derived superoxide anion
    • Erdei N, Toth A, Pasztor ET, et al. (2006) High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: role of xanthine oxidase-derived superoxide anion. Am J Physiol Heart Circ Physiol 291, H2107-H2115
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H2107-H2115
    • Erdei, N.1    Toth, A.2    Pasztor, E.T.3
  • 40
    • 23644439439 scopus 로고    scopus 로고
    • Compromised arterial function in human type 2 diabetic patients
    • Okon EB, Chung AW, Rauniyar P, et al. (2005) Compromised arterial function in human type 2 diabetic patients. Diabetes 54, 2415-2423
    • (2005) Diabetes , vol.54 , pp. 2415-2423
    • Okon, E.B.1    Chung, A.W.2    Rauniyar, P.3
  • 41
    • 0442309045 scopus 로고    scopus 로고
    • Augmented contractile response of vascular smooth muscle in a diabetic mouse model
    • Okon EB, Szado T, Laher I, et al. (2003) Augmented contractile response of vascular smooth muscle in a diabetic mouse model. J Vasc Res 40, 520-530
    • (2003) J Vasc Res , vol.40 , pp. 520-530
    • Okon, E.B.1    Szado, T.2    Laher, I.3
  • 42
    • 0141788776 scopus 로고    scopus 로고
    • Superoxide-NO interaction decreases flow-and agonist-induced dilations of coronary arterioles in type 2 diabetes mellitus
    • Bagi Z, Koller A &Kaley G (2003) Superoxide-NO interaction decreases flow-and agonist-induced dilations of coronary arterioles in type 2 diabetes mellitus. Am J Physiol Heart Circ Physiol 285, H1404-H1410
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H1404-H1410
    • Bagi, Z.1    Koller, A.2    Kaley, G.3
  • 43
    • 1442335807 scopus 로고    scopus 로고
    • Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase-mediated production of superoxide and cytokines via lectin-like oxidized low-density lipoprotein receptor-1 activation: Prevention by cilostazol
    • Shin HK, Kim YK, Kim KY, et al. (2004) Remnant lipoprotein particles induce apoptosis in endothelial cells by NAD(P)H oxidase-mediated production of superoxide and cytokines via lectin-like oxidized low-density lipoprotein receptor-1 activation: prevention by cilostazol. Circulation 109, 1022-1028
    • (2004) Circulation , vol.109 , pp. 1022-1028
    • Shin, H.K.1    Kim, Y.K.2    Kim, K.Y.3
  • 44
    • 18344366874 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and aging
    • Lenaz G, Bovina C, D'Aurelio M, et al. (2002) Role of mitochondria in oxidative stress and aging. Ann N Y Acad Sci 959, 199-213
    • (2002) Ann N y Acad Sci , vol.959 , pp. 199-213
    • Lenaz, G.1    Bovina, C.2    D'Aurelio, M.3
  • 45
    • 84864774722 scopus 로고    scopus 로고
    • Mitochondrial function in vascular endothelial cell in diabetes
    • Pangare M &Makino A (2012) Mitochondrial function in vascular endothelial cell in diabetes. J Smooth Muscle Res 48, 1-26
    • (2012) J Smooth Muscle Res , vol.48 , pp. 1-26
    • Pangare, M.1    Makino, A.2
  • 46
    • 34247598856 scopus 로고    scopus 로고
    • Endothelial mitochondria: Contributing to vascular function and disease
    • Davidson SM &Duchen MR (2007) Endothelial mitochondria: contributing to vascular function and disease. Circ Res 100, 1128-1141
    • (2007) Circ Res , vol.100 , pp. 1128-1141
    • Davidson, S.M.1    Duchen, M.R.2
  • 47
    • 77955509429 scopus 로고    scopus 로고
    • Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes
    • Makino A, Scott BT &Dillmann WH (2010) Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes. Diabetologia 53, 1783-1794
    • (2010) Diabetologia , vol.53 , pp. 1783-1794
    • Makino, A.1    Scott, B.T.2    Dillmann, W.H.3
  • 48
    • 0242349764 scopus 로고    scopus 로고
    • Oxidative stress and cardiovascular injury: Part II: Animal and human studies
    • Griendling KK &FitzGerald GA (2003) Oxidative stress and cardiovascular injury: part II: animal and human studies. Circulation 108, 2034-2040
    • (2003) Circulation , vol.108 , pp. 2034-2040
    • Griendling, K.K.1    FitzGerald, G.A.2
  • 49
    • 80051666038 scopus 로고    scopus 로고
    • Reactive oxygen species in cardiovascular disease
    • Sugamura K &Keaney JF Jr (2011) Reactive oxygen species in cardiovascular disease. Free Radic Biol Med 51, 978-992
    • (2011) Free Radic Biol Med , vol.51 , pp. 978-992
    • Sugamura, K.1    Keaney, J.F.2
  • 50
    • 41149150716 scopus 로고    scopus 로고
    • NADPH oxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities
    • Paravicini TM &Touyz RM (2008) NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 31, Suppl. 2, S170-S180
    • (2008) Diabetes Care , vol.31 , pp. S170-S180
    • Paravicini, T.M.1    Touyz, R.M.2
  • 51
    • 34250858839 scopus 로고    scopus 로고
    • Reactive oxygen species-selective regulation of aortic inflammatory gene expression in type 2 diabetes
    • San Martin A, Du P, Dikalova A, et al. (2007) Reactive oxygen species-selective regulation of aortic inflammatory gene expression in type 2 diabetes. Am J Physiol Heart Circ Physiol 292, H2073-H2082
    • (2007) Am J Physiol Heart Circ Physiol , vol.292 , pp. H2073-H2082
    • San, M.A.1    Du, P.2    Dikalova, A.3
  • 52
    • 85011392400 scopus 로고    scopus 로고
    • Hyperglycemiamediated oxidative stress increases pulmonary vascular permeability
    • Clemmer JS, Xiang L, Lu S, et al. (2016) Hyperglycemiamediated oxidative stress increases pulmonary vascular permeability. Microcirculation 23, 221-229
    • (2016) Microcirculation , vol.23 , pp. 221-229
    • Clemmer, J.S.1    Xiang, L.2    Lu, S.3
  • 53
    • 0038476475 scopus 로고    scopus 로고
    • Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice
    • Matsumoto S, Koshiishi I, Inoguchi T, et al. (2003) Confirmation of superoxide generation via xanthine oxidase in streptozotocin-induced diabetic mice. Free Radic Res 37, 767-772
    • (2003) Free Radic Res , vol.37 , pp. 767-772
    • Matsumoto, S.1    Koshiishi, I.2    Inoguchi, T.3
  • 54
    • 0034065857 scopus 로고    scopus 로고
    • Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension
    • Butler R, Morris AD, Belch JJ, et al. (2000) Allopurinol normalizes endothelial dysfunction in type 2 diabetics with mild hypertension. Hypertension 35, 746-751
    • (2000) Hypertension , vol.35 , pp. 746-751
    • Butler, R.1    Morris, A.D.2    Belch, J.J.3
  • 55
    • 33947253955 scopus 로고    scopus 로고
    • Treatment with the xanthine oxidase inhibitor, allopurinol, improves nerve and vascular function in diabetic rats
    • Inkster ME, Cotter MA &Cameron NE (2007) Treatment with the xanthine oxidase inhibitor, allopurinol, improves nerve and vascular function in diabetic rats. Eur J Pharmacol 561, 63-71
    • (2007) Eur J Pharmacol , vol.561 , pp. 63-71
    • Inkster, M.E.1    Cotter, M.A.2    Cameron, N.E.3
  • 56
    • 33645780634 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase in vascular disease: From marvel to menace
    • Forstermann U &Munzel T (2006) Endothelial nitric oxide synthase in vascular disease: from marvel to menace. Circulation 113, 1708-1714
    • (2006) Circulation , vol.113 , pp. 1708-1714
    • Forstermann, U.1    Munzel, T.2
  • 57
    • 0035053883 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase (eNOS) expression and localization in healthy and diabetic rat hearts
    • Felaco M, Grilli A, De Lutiis MA, et al. (2001) Endothelial nitric oxide synthase (eNOS) expression and localization in healthy and diabetic rat hearts. Ann Clin Lab Sci 31, 179-186
    • (2001) Ann Clin Lab Sci , vol.31 , pp. 179-186
    • Felaco, M.1    Grilli, A.2    De Lutiis, M.A.3
  • 58
    • 0141919595 scopus 로고    scopus 로고
    • Mechanisms of endothelial dysfunction: Clinical significance and preventive non-pharmacological therapeutic strategies
    • Taddei S, Ghiadoni L, Virdis A, et al. (2003) Mechanisms of endothelial dysfunction: clinical significance and preventive non-pharmacological therapeutic strategies. Curr Pharm Des 9, 2385-2402
    • (2003) Curr Pharm des , vol.9 , pp. 2385-2402
    • Taddei, S.1    Ghiadoni, L.2    Virdis, A.3
  • 59
    • 0035960677 scopus 로고    scopus 로고
    • Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease
    • Heitzer T, Schlinzig T, Krohn K, et al. (2001) Endothelial dysfunction, oxidative stress, and risk of cardiovascular events in patients with coronary artery disease. Circulation 104, 2673-2678
    • (2001) Circulation , vol.104 , pp. 2673-2678
    • Heitzer, T.1    Schlinzig, T.2    Krohn, K.3
  • 60
    • 0033752910 scopus 로고    scopus 로고
    • Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with type II diabetes mellitus
    • Heitzer T, Krohn K, Albers S, et al. (2000) Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with type II diabetes mellitus. Diabetologia 43, 1435-1438
    • (2000) Diabetologia , vol.43 , pp. 1435-1438
    • Heitzer, T.1    Krohn, K.2    Albers, S.3
  • 61
    • 77956283047 scopus 로고    scopus 로고
    • CGMPdependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action
    • Francis SH, Busch JL, Corbin JD, et al. (2010) cGMPdependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action. Pharmacol Rev 62, 525-563
    • (2010) Pharmacol Rev , vol.62 , pp. 525-563
    • Francis, S.H.1    Busch, J.L.2    Corbin, J.D.3
  • 62
    • 0036276724 scopus 로고    scopus 로고
    • Obesity, atherosclerosis and the vascular endothelium: Mechanisms of reduced nitric oxide bioavailability in obese humans
    • Williams IL, Wheatcroft SB, Shah AM, et al. (2002) Obesity, atherosclerosis and the vascular endothelium: mechanisms of reduced nitric oxide bioavailability in obese humans. Int J Obes Relat Metab Disord 26, 754-764
    • (2002) J Obes Relat Metab Disord , vol.26 , pp. 754-764
    • Williams, I.L.1    Wheatcroft, S.B.2    Shah, A.M.3
  • 63
    • 77956386834 scopus 로고    scopus 로고
    • Reactive oxygen-derived free radicals are key to the endothelial dysfunction of diabetes
    • Shi Y &Vanhoutte PM (2009) Reactive oxygen-derived free radicals are key to the endothelial dysfunction of diabetes. J Diabetes 1, 151-162
    • (2009) J Diabetes , vol.1 , pp. 151-162
    • Shi, Y.1    Vanhoutte, P.M.2
  • 64
    • 0032416666 scopus 로고    scopus 로고
    • Crystal structure of constitutive endothelial nitric oxide synthase: A paradigm for pterin function involving a novel metal center
    • Raman CS, Li H, Martasek P, et al. (1998) Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center. Cell 95, 939-950
    • (1998) Cell , vol.95 , pp. 939-950
    • Raman, C.S.1    Li, H.2    Martasek, P.3
  • 65
    • 34447302843 scopus 로고    scopus 로고
    • Regulation of muscle blood flow in obesity
    • Hodnett BL &Hester RL (2007) Regulation of muscle blood flow in obesity. Microcirculation 14, 273-288
    • (2007) Microcirculation , vol.14 , pp. 273-288
    • Hodnett, B.L.1    Hester, R.L.2
  • 66
    • 0035793616 scopus 로고    scopus 로고
    • Mechanisms underlying endothelial dysfunction in diabetes mellitus
    • Hink U, Li H, Mollnau H, et al. (2001) Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res 88, E14-E22
    • (2001) Circ Res , vol.88 , pp. E14-E22
    • Hink, U.1    Li, H.2    Mollnau, H.3
  • 67
    • 0037143637 scopus 로고    scopus 로고
    • Impaired nitric oxide synthase pathway in diabetes mellitus: Role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase
    • Lin KY, Ito A, Asagami T, et al. (2002) Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase. Circulation 106, 987-992
    • (2002) Circulation , vol.106 , pp. 987-992
    • Lin, K.Y.1    Ito, A.2    Asagami, T.3
  • 68
    • 23244459293 scopus 로고    scopus 로고
    • Vascular consequences of endothelial nitric oxide synthase uncoupling for the activity and expression of the soluble guanylyl cyclase and the cGMP-dependent protein kinase
    • Munzel T, Daiber A, Ullrich V, et al. (2005) Vascular consequences of endothelial nitric oxide synthase uncoupling for the activity and expression of the soluble guanylyl cyclase and the cGMP-dependent protein kinase. Arterioscler Thromb Vasc Biol 25, 1551-1557
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1551-1557
    • Munzel, T.1    Daiber, A.2    Ullrich, V.3
  • 69
    • 44449089304 scopus 로고    scopus 로고
    • Plasma concentration of asymmetric dimethylarginine (ADMA) predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy
    • Lajer M, Tarnow L, Jorsal A, et al. (2008) Plasma concentration of asymmetric dimethylarginine (ADMA) predicts cardiovascular morbidity and mortality in type 1 diabetic patients with diabetic nephropathy. Diabetes Care 31, 747-752
    • (2008) Diabetes Care , vol.31 , pp. 747-752
    • Lajer, M.1    Tarnow, L.2    Jorsal, A.3
  • 70
    • 34447120049 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes
    • Krzyzanowska K, Mittermayer F, Wolzt M, et al. (2007) Asymmetric dimethylarginine predicts cardiovascular events in patients with type 2 diabetes. Diabetes Care 30, 1834-1839
    • (2007) Diabetes Care , vol.30 , pp. 1834-1839
    • Krzyzanowska, K.1    Mittermayer, F.2    Wolzt, M.3
  • 71
    • 41349096436 scopus 로고    scopus 로고
    • Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension
    • Schulz E, Jansen T, Wenzel P, et al. (2008) Nitric oxide, tetrahydrobiopterin, oxidative stress, and endothelial dysfunction in hypertension. Antioxid Redox Signal 10, 1115-1126
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1115-1126
    • Schulz, E.1    Jansen, T.2    Wenzel, P.3
  • 72
    • 77957764137 scopus 로고    scopus 로고
    • Hyperglycemia-induced endoplasmic reticulum stress in endothelial cells
    • Sheikh-Ali M, Sultan S, Alamir AR, et al. (2010) Hyperglycemia-induced endoplasmic reticulum stress in endothelial cells. Nutrition 26, 1146-1150
    • (2010) Nutrition , vol.26 , pp. 1146-1150
    • Sheikh-Ali, M.1    Sultan, S.2    Alamir, A.R.3
  • 73
    • 0034610743 scopus 로고    scopus 로고
    • Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta
    • Nakagawa T, Zhu H, Morishima N, et al. (2000) Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. Nature 403, 98-103
    • (2000) Nature , vol.403 , pp. 98-103
    • Nakagawa, T.1    Zhu, H.2    Morishima, N.3
  • 74
    • 0036606540 scopus 로고    scopus 로고
    • ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
    • Nishitoh H, Matsuzawa A, Tobiume K, et al. (2002) ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats. Genes Dev 16, 1345-1355
    • (2002) Genes Dev , vol.16 , pp. 1345-1355
    • Nishitoh, H.1    Matsuzawa, A.2    Tobiume, K.3
  • 75
    • 0036314984 scopus 로고    scopus 로고
    • Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response
    • Ma Y, Brewer JW, Diehl JA, et al. (2002) Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response. J Mol Biol 318, 1351-1365
    • (2002) J Mol Biol , vol.318 , pp. 1351-1365
    • Ma, Y.1    Brewer, J.W.2    Diehl, J.A.3
  • 76
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan U, Cao Q, Yilmaz E, et al. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-461
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1    Cao, Q.2    Yilmaz, E.3
  • 77
    • 84858155133 scopus 로고    scopus 로고
    • Activation of hexosamine pathway impairs nitric oxide (NO)-dependent arteriolar dilations by increased protein O-GlcNAcylation
    • Beleznai T &Bagi Z (2012) Activation of hexosamine pathway impairs nitric oxide (NO)-dependent arteriolar dilations by increased protein O-GlcNAcylation. Vascul Pharmacol 56, 115-121
    • (2012) Vascul Pharmacol , vol.56 , pp. 115-121
    • Beleznai, T.1    Bagi, Z.2
  • 78
    • 42249106688 scopus 로고    scopus 로고
    • Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells
    • Luo B, Soesanto Y &McClain DA (2008) Protein modification by O-linked GlcNAc reduces angiogenesis by inhibiting Akt activity in endothelial cells. Arterioscler Thromb Vasc Biol 28, 651-657
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 651-657
    • Luo, B.1    Soesanto, Y.2    McClain, D.A.3
  • 79
    • 84936763022 scopus 로고    scopus 로고
    • Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling
    • Scallan JP, Hill MA &Davis MJ (2015) Lymphatic vascular integrity is disrupted in type 2 diabetes due to impaired nitric oxide signalling. Cardiovasc Res 107, 89-97
    • (2015) Cardiovasc Res , vol.107 , pp. 89-97
    • Scallan, J.P.1    Hill, M.A.2    Davis, M.J.3
  • 80
    • 0028113927 scopus 로고
    • Nitric oxide release accounts for insulin's vascular effects in humans
    • Scherrer U, Randin D, Vollenweider P, et al. (1994) Nitric oxide release accounts for insulin's vascular effects in humans. J Clin Invest 94, 2511-2515
    • (1994) J Clin Invest , vol.94 , pp. 2511-2515
    • Scherrer, U.1    Randin, D.2    Vollenweider, P.3
  • 81
    • 0028316832 scopus 로고
    • Skeletal muscle blood flow independently modulates insulin-mediated glucose uptake
    • Baron AD, Steinberg H, Brechtel G, et al. (1994) Skeletal muscle blood flow independently modulates insulin-mediated glucose uptake. Am J Physiol 266, E248-E253
    • (1994) Am J Physiol , vol.266 , pp. E248-E253
    • Baron, A.D.1    Steinberg, H.2    Brechtel, G.3
  • 82
    • 1342343980 scopus 로고    scopus 로고
    • Insulin induced increase in coronary flow reserve is abolished by dexamethasone in young men with uncomplicated type 1 diabetes
    • Laine H, Sundell J, Nuutila P, et al. (2004) Insulin induced increase in coronary flow reserve is abolished by dexamethasone in young men with uncomplicated type 1 diabetes. Heart 90, 270-276
    • (2004) Heart , vol.90 , pp. 270-276
    • Laine, H.1    Sundell, J.2    Nuutila, P.3
  • 83
    • 0036033773 scopus 로고    scopus 로고
    • Mismatch between insulin-mediated glucose uptake and blood flow in the heart of patients with type II diabetes
    • Iozzo P, Chareonthaitawee P, Rimoldi O, et al. (2002) Mismatch between insulin-mediated glucose uptake and blood flow in the heart of patients with type II diabetes. Diabetologia 45, 1404-1409
    • (2002) Diabetologia , vol.45 , pp. 1404-1409
    • Iozzo, P.1    Chareonthaitawee, P.2    Rimoldi, O.3
  • 84
    • 84958761533 scopus 로고    scopus 로고
    • Insulin action in muscle and adipose tissue in type 2 diabetes: The significance of blood flow
    • Lambadiari V, Triantafyllou K &Dimitriadis GD (2015) Insulin action in muscle and adipose tissue in type 2 diabetes: the significance of blood flow. World J Diabetes 6, 626-633
    • (2015) World J Diabetes , vol.6 , pp. 626-633
    • Lambadiari, V.1    Triantafyllou, K.2    Dimitriadis, G.D.3
  • 85
    • 84856714966 scopus 로고    scopus 로고
    • Failure to increase postprandial blood flow in subcutaneous adipose tissue is associated with tissue resistance to adrenergic stimulation
    • Ardilouze JL, Sotornik R, Dennis LA, et al. (2012) Failure to increase postprandial blood flow in subcutaneous adipose tissue is associated with tissue resistance to adrenergic stimulation. Diabetes Metab 38, 27-33
    • (2012) Diabetes Metab , vol.38 , pp. 27-33
    • Ardilouze, J.L.1    Sotornik, R.2    Dennis, L.A.3
  • 86
    • 0019432562 scopus 로고
    • Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice
    • Langille BL &Adamson SL (1981) Relationship between blood flow direction and endothelial cell orientation at arterial branch sites in rabbits and mice. Circ Res 48, 481-488
    • (1981) Circ Res , vol.48 , pp. 481-488
    • Langille, B.L.1    Adamson, S.L.2
  • 87
    • 78649935272 scopus 로고    scopus 로고
    • Endothelial cell dysfunction in hyperglycemia: Phenotypic change, intracellular signaling modification, ultrastructural alteration, and potential clinical outcomes
    • Popov D (2010) Endothelial cell dysfunction in hyperglycemia: phenotypic change, intracellular signaling modification, ultrastructural alteration, and potential clinical outcomes. Int J Diabetes Mellit 2, 189-195
    • (2010) J Diabetes Mellit , vol.2 , pp. 189-195
    • Popov, D.1
  • 88
    • 52649084275 scopus 로고    scopus 로고
    • The pathophysiology of cardiovascular disease and diabetes: Beyond blood pressure and lipids
    • Dokken BB (2008) The pathophysiology of cardiovascular disease and diabetes: beyond blood pressure and lipids. Diabetes Spectr 21, 160-165
    • (2008) Diabetes Spectr , vol.21 , pp. 160-165
    • Dokken, B.B.1
  • 89
    • 33846457372 scopus 로고    scopus 로고
    • Implications of early structural-functional changes in the endothelium for vascular disease
    • Simionescu M (2007) Implications of early structural-functional changes in the endothelium for vascular disease. Arterioscler Thromb Vasc Biol 27, 266-274
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 266-274
    • Simionescu, M.1
  • 90
    • 0035312620 scopus 로고    scopus 로고
    • Improved endothelial function with metformin in type 2 diabetes mellitus
    • Mather KJ, Verma S &Anderson TJ (2001) Improved endothelial function with metformin in type 2 diabetes mellitus. J Am Coll Cardiol 37, 1344-1350
    • (2001) J Am Coll Cardiol , vol.37 , pp. 1344-1350
    • Mather, K.J.1    Verma, S.2    Anderson, T.J.3
  • 91
    • 84890174009 scopus 로고    scopus 로고
    • Long-term effects of metformin on endothelial function in type 2 diabetes: A randomized controlled trial
    • de Jager J, Kooy A, Schalkwijk C, et al. (2014) Long-term effects of metformin on endothelial function in type 2 diabetes: a randomized controlled trial. J Intern Med 275, 59-70
    • (2014) J Intern Med , vol.275 , pp. 59-70
    • De Jager, J.1    Kooy, A.2    Schalkwijk, C.3
  • 92
    • 60549097258 scopus 로고    scopus 로고
    • Targeting incretins in type 2 diabetes: Role of GLP-1 receptor agonists and DPP-4 inhibitors
    • Pratley RE &Gilbert M (2008) Targeting incretins in type 2 diabetes: role of GLP-1 receptor agonists and DPP-4 inhibitors. Rev Diabet Stud 5, 73-94
    • (2008) Rev Diabet Stud , vol.5 , pp. 73-94
    • Pratley, R.E.1    Gilbert, M.2
  • 93
    • 84949110416 scopus 로고    scopus 로고
    • Exenatide protects against glucose-and lipid-induced endothelial dysfunction: Evidence for direct vasodilation effect of GLP-1 receptor agonists in humans
    • Koska J, Sands M, Burciu C, et al. (2015) Exenatide protects against glucose-and lipid-induced endothelial dysfunction: evidence for direct vasodilation effect of GLP-1 receptor agonists in humans. Diabetes 64, 2624-2635
    • (2015) Diabetes , vol.64 , pp. 2624-2635
    • Koska, J.1    Sands, M.2    Burciu, C.3
  • 94
    • 84924284871 scopus 로고    scopus 로고
    • Effects of exenatide on postprandial vascular endothelial dysfunction in type 2 diabetes mellitus
    • Torimoto K, Okada Y, Mori H, et al. (2015) Effects of exenatide on postprandial vascular endothelial dysfunction in type 2 diabetes mellitus. Cardiovasc Diabetol 14, 25
    • (2015) Cardiovasc Diabetol , vol.14 , pp. 25
    • Torimoto, K.1    Okada, Y.2    Mori, H.3
  • 95
    • 84920136833 scopus 로고    scopus 로고
    • Diabetic nephropathy: Treatment with phosphodiesterase type 5 inhibitors
    • Thompson CS (2013) Diabetic nephropathy: treatment with phosphodiesterase type 5 inhibitors. World J Diabetes 4, 124-129
    • (2013) World J Diabetes , vol.4 , pp. 124-129
    • Thompson, C.S.1
  • 96
    • 79951979701 scopus 로고    scopus 로고
    • Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats
    • Kuno Y, Iyoda M, Shibata T, et al. (2011) Sildenafil, a phosphodiesterase type 5 inhibitor, attenuates diabetic nephropathy in non-insulin-dependent Otsuka Long-Evans Tokushima Fatty rats. Br J Pharmacol 162, 1389-1400
    • (2011) Br J Pharmacol , vol.162 , pp. 1389-1400
    • Kuno, Y.1    Iyoda, M.2    Shibata, T.3
  • 97
    • 84862908699 scopus 로고    scopus 로고
    • A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice
    • Matsubara J, Sugiyama S, Sugamura K, et al. (2012) A dipeptidyl peptidase-4 inhibitor, des-fluoro-sitagliptin, improves endothelial function and reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice. J Am Coll Cardiol 59, 265-276
    • (2012) J Am Coll Cardiol , vol.59 , pp. 265-276
    • Matsubara, J.1    Sugiyama, S.2    Sugamura, K.3
  • 98
    • 83455230038 scopus 로고    scopus 로고
    • Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes
    • van Poppel PC, Netea MG, Smits P, et al. (2011) Vildagliptin improves endothelium-dependent vasodilatation in type 2 diabetes. Diabetes Care 34, 2072-2077
    • (2011) Diabetes Care , vol.34 , pp. 2072-2077
    • Van Poppel, P.C.1    Netea, M.G.2    Smits, P.3
  • 99
    • 84892576563 scopus 로고    scopus 로고
    • Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia
    • Rieg T, Masuda T, Gerasimova M, et al. (2014) Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. Am J Physiol Renal Physiol 306, F188-F193
    • (2014) Am J Physiol Renal Physiol , vol.306 , pp. F188-F193
    • Rieg, T.1    Masuda, T.2    Gerasimova, M.3
  • 100
    • 84911942671 scopus 로고    scopus 로고
    • The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity
    • Oelze M, Kroller-Schon S, Welschof P, et al. (2014) The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity. PLOS ONE 9, e112394
    • (2014) PLOS ONE , vol.9 , pp. e112394
    • Oelze, M.1    Kroller-Schon, S.2    Welschof, P.3
  • 101
    • 84946434020 scopus 로고    scopus 로고
    • SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery
    • Han Y, Cho YE, Ayon R, et al. (2015) SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery. Am J Physiol Lung Cell Mol Physiol 309, L1027-L1036
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.309 , pp. L1027-L1036
    • Han, Y.1    Cho, Y.E.2    Ayon, R.3
  • 102
    • 34547636112 scopus 로고    scopus 로고
    • Heme oxygenase-1: A novel key player in the development of tolerance in response to organic nitrates
    • Wenzel P, Oelze M, Coldewey M, et al. (2007) Heme oxygenase-1: a novel key player in the development of tolerance in response to organic nitrates. Arterioscler Thromb Vasc Biol 27, 1729-1735
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1729-1735
    • Wenzel, P.1    Oelze, M.2    Coldewey, M.3
  • 103
    • 80053425581 scopus 로고    scopus 로고
    • Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy
    • Schuhmacher S, Oelze M, Bollmann F, et al. (2011) Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy. Diabetes 60, 2608-2616
    • (2011) Diabetes , vol.60 , pp. 2608-2616
    • Schuhmacher, S.1    Oelze, M.2    Bollmann, F.3
  • 104
    • 0034677448 scopus 로고    scopus 로고
    • Effect of exercise on coronary endothelial function in patients with coronary artery disease
    • Hambrecht R, Wolf A, Gielen S, et al. (2000) Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 342, 454-460
    • (2000) N Engl J Med , vol.342 , pp. 454-460
    • Hambrecht, R.1    Wolf, A.2    Gielen, S.3
  • 105
    • 0036780574 scopus 로고    scopus 로고
    • Exercise training improves vascular endothelial function in patients with type 1 diabetes
    • Fuchsjager-Mayrl G, Pleiner J, Wiesinger GF, et al. (2002) Exercise training improves vascular endothelial function in patients with type 1 diabetes. Diabetes Care 25, 1795-1801
    • (2002) Diabetes Care , vol.25 , pp. 1795-1801
    • Fuchsjager-Mayrl, G.1    Pleiner, J.2    Wiesinger, G.F.3
  • 106
    • 78651350292 scopus 로고    scopus 로고
    • Exercise and type 2 diabetes: The American College of Sports Medicine and the American Diabetes Association: Joint position statement executive summary
    • Colberg SR, Sigal RJ, Fernhall B, et al. (2010) Exercise and type 2 diabetes: the American College of Sports Medicine and the American Diabetes Association: joint position statement executive summary. Diabetes Care 33, 2692-2696
    • (2010) Diabetes Care , vol.33 , pp. 2692-2696
    • Colberg, S.R.1    Sigal, R.J.2    Fernhall, B.3
  • 107
    • 0035850403 scopus 로고    scopus 로고
    • Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: A meta-analysis of controlled clinical trials
    • Boule NG, Haddad E, Kenny GP, et al. (2001) Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA 286, 1218-1227
    • (2001) JAMA , vol.286 , pp. 1218-1227
    • Boule, N.G.1    Haddad, E.2    Kenny, G.P.3
  • 108
    • 84855177888 scopus 로고    scopus 로고
    • Exercise training prevents coronary endothelial dysfunction in type 2 diabetic mice
    • Lee S, Park Y &Zhang C (2011) Exercise training prevents coronary endothelial dysfunction in type 2 diabetic mice. Am J Biomed Sci 3, 241-252
    • (2011) Am J Biomed Sci , vol.3 , pp. 241-252
    • Lee, S.1    Park, Y.2    Zhang, C.3
  • 109
    • 79951659977 scopus 로고    scopus 로고
    • Ascorbic acid prevents oxidant-induced increases in endothelial permeability
    • May JM &Qu ZC (2011) Ascorbic acid prevents oxidant-induced increases in endothelial permeability. Biofactors 37, 46-50
    • (2011) Biofactors , vol.37 , pp. 46-50
    • May, J.M.1    Qu, Z.C.2
  • 110
    • 34447126846 scopus 로고    scopus 로고
    • Telmisartan shows an equivalent effect of Vitamin C in further improving endothelial dysfunction after glycemia normalization in type 1 diabetes
    • Ceriello A, Piconi L, Esposito K, et al. (2007) Telmisartan shows an equivalent effect of vitamin C in further improving endothelial dysfunction after glycemia normalization in type 1 diabetes. Diabetes Care 30, 1694-1698
    • (2007) Diabetes Care , vol.30 , pp. 1694-1698
    • Ceriello, A.1    Piconi, L.2    Esposito, K.3
  • 111
    • 84870058776 scopus 로고    scopus 로고
    • Ascorbic acid blocks hyperglycemic impairment of endothelial function in adolescents with type 1 diabetes
    • Hoffman RP, Dye AS &Bauer JA (2012) Ascorbic acid blocks hyperglycemic impairment of endothelial function in adolescents with type 1 diabetes. Pediatr Diabetes 13, 607-610
    • (2012) Pediatr Diabetes , vol.13 , pp. 607-610
    • Hoffman, R.P.1    Dye, A.S.2    Bauer, J.A.3
  • 112
    • 84958771225 scopus 로고    scopus 로고
    • Ascorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: Findings of a randomized controlled study
    • Mason SA, Della Gatta PA, Snow RJ, et al. (2016) Ascorbic acid supplementation improves skeletal muscle oxidative stress and insulin sensitivity in people with type 2 diabetes: findings of a randomized controlled study. Free Radic Biol Med 93, 227-238
    • (2016) Free Radic Biol Med , vol.93 , pp. 227-238
    • Mason, S.A.1    Della Gatta, P.A.2    Snow, R.J.3
  • 113
    • 40449102805 scopus 로고    scopus 로고
    • The effect of oral folic acid upon plasma homocysteine, endothelial function and oxidative stress in patients with type 1 diabetes and microalbuminuria
    • Wotherspoon F, Laight DW, Turner C, et al. (2008) The effect of oral folic acid upon plasma homocysteine, endothelial function and oxidative stress in patients with type 1 diabetes and microalbuminuria. Int J Clin Pract 62, 569-574
    • (2008) J Clin Pract , vol.62 , pp. 569-574
    • Wotherspoon, F.1    Laight, D.W.2    Turner, C.3
  • 114
    • 84867402014 scopus 로고    scopus 로고
    • Effect of folic acid supplementation on plasma total homocysteine levels and glycemic control in patients with type 2 diabetes: A systematic review and meta-analysis
    • Sudchada P, Saokaew S, Sridetch S, et al. (2012) Effect of folic acid supplementation on plasma total homocysteine levels and glycemic control in patients with type 2 diabetes: a systematic review and meta-analysis. Diabetes Res Clin Pract 98, 151-158
    • (2012) Diabetes Res Clin Pract , vol.98 , pp. 151-158
    • Sudchada, P.1    Saokaew, S.2    Sridetch, S.3
  • 115
    • 0036300151 scopus 로고    scopus 로고
    • Endothelial dysfunction relates to folate status in children and adolescents with type 1 diabetes
    • Wiltshire EJ, Gent R, Hirte C, et al. (2002) Endothelial dysfunction relates to folate status in children and adolescents with type 1 diabetes. Diabetes 51, 2282-2286
    • (2002) Diabetes , vol.51 , pp. 2282-2286
    • Wiltshire, E.J.1    Gent, R.2    Hirte, C.3
  • 116
    • 84903976239 scopus 로고    scopus 로고
    • Effects of folic acid on renal endothelial function in patients with diabetic nephropathy: Results from a randomized trial
    • Schneider MP, Schneider A, Jumar A, et al. (2014) Effects of folic acid on renal endothelial function in patients with diabetic nephropathy: results from a randomized trial. Clin Sci (Lond) 127, 499-505
    • (2014) Clin Sci (Lond) , vol.127 , pp. 499-505
    • Schneider, M.P.1    Schneider, A.2    Jumar, A.3
  • 117
    • 71749111560 scopus 로고    scopus 로고
    • Cancer incidence and mortality after treatment with folic acid and vitamin B12
    • Ebbing M, Bonaa KH, Nygard O, et al. (2009) Cancer incidence and mortality after treatment with folic acid and vitamin B12. JAMA 302, 2119-2126
    • (2009) JAMA , vol.302 , pp. 2119-2126
    • Ebbing, M.1    Bonaa, K.H.2    Nygard, O.3
  • 118
    • 84873473168 scopus 로고    scopus 로고
    • Randomized controlled trial of Vitamin D supplement on endothelial function in patients with type 2 diabetes
    • Yiu YF, Yiu KH, Siu CW, et al. (2013) Randomized controlled trial of vitamin D supplement on endothelial function in patients with type 2 diabetes. Atherosclerosis 227, 140-146
    • (2013) Atherosclerosis , vol.227 , pp. 140-146
    • Yiu, Y.F.1    Yiu, K.H.2    Siu, C.W.3
  • 120
    • 84869054252 scopus 로고    scopus 로고
    • Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients
    • Riek AE, Oh J, Sprague JE, et al. (2012) Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients. J Biol Chem 287, 38482-38494
    • (2012) J Biol Chem , vol.287 , pp. 38482-38494
    • Riek, A.E.1    Oh, J.2    Sprague, J.E.3
  • 121
    • 0037381984 scopus 로고    scopus 로고
    • Effect of chronic treatment with Vitamin E on endothelial dysfunction in a type i in vivo diabetes mellitus model and in vitro
    • Dhein S, Kabat A, Olbrich A, et al. (2003) Effect of chronic treatment with vitamin E on endothelial dysfunction in a type I in vivo diabetes mellitus model and in vitro. J Pharmacol Exp Ther 305, 114-122
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 114-122
    • Dhein, S.1    Kabat, A.2    Olbrich, A.3
  • 122
    • 0033910718 scopus 로고    scopus 로고
    • Vitamin E supplementation improves endothelial function in type i diabetes mellitus: A randomized, placebo-controlled study
    • Skyrme-Jones RA, O'Brien RC, Berry KL, et al. (2000) Vitamin E supplementation improves endothelial function in type I diabetes mellitus: a randomized, placebo-controlled study. J Am Coll Cardiol 36, 94-102
    • (2000) J Am Coll Cardiol , vol.36 , pp. 94-102
    • Skyrme-Jones, R.A.1    O'Brien, R.C.2    Berry, K.L.3
  • 123
    • 19944428613 scopus 로고    scopus 로고
    • The effect of Vitamin E on endothelial function of micro-and macrocirculation and left ventricular function in type 1 and type 2 diabetic patients
    • Economides PA, Khaodhiar L, Caselli A, et al. (2005) The effect of vitamin E on endothelial function of micro-and macrocirculation and left ventricular function in type 1 and type 2 diabetic patients. Diabetes 54, 204-211
    • (2005) Diabetes , vol.54 , pp. 204-211
    • Economides, P.A.1    Khaodhiar, L.2    Caselli, A.3
  • 124
    • 84859098613 scopus 로고    scopus 로고
    • Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: An update for clinicians
    • Habauzit V &Morand C (2012) Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: an update for clinicians. Ther Adv Chronic Dis 3, 87-106
    • (2012) Ther Adv Chronic Dis , vol.3 , pp. 87-106
    • Habauzit, V.1    Morand, C.2
  • 125
    • 84904727810 scopus 로고    scopus 로고
    • Vascular endothelial dysfunction and nutritional compounds in early type 1 diabetes
    • Hoffman RP (2014) Vascular endothelial dysfunction and nutritional compounds in early type 1 diabetes. Curr Diabetes Rev 10, 201-207
    • (2014) Curr Diabetes Rev , vol.10 , pp. 201-207
    • Hoffman, R.P.1
  • 126
    • 33645453199 scopus 로고    scopus 로고
    • Red grapefruit positively influences serum triglyceride level in patients suffering from coronary atherosclerosis: Studies in vitro and in humans
    • Gorinstein S, Caspi A, Libman I, et al. (2006) Red grapefruit positively influences serum triglyceride level in patients suffering from coronary atherosclerosis: studies in vitro and in humans. J Agric Food Chem 54, 1887-1892
    • (2006) J Agric Food Chem , vol.54 , pp. 1887-1892
    • Gorinstein, S.1    Caspi, A.2    Libman, I.3
  • 127
    • 0036228345 scopus 로고    scopus 로고
    • Inverse association of tea and flavonoid intakes with incident myocardial infarction: The Rotterdam Study
    • Geleijnse JM, Launer LJ, Van der Kuip DA, et al. (2002) Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study. Am J Clin Nutr 75, 880-886
    • (2002) Am J Clin Nutr , vol.75 , pp. 880-886
    • Geleijnse, J.M.1    Launer, L.J.2    Van Der Kuip, D.A.3
  • 128
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans I. Review of 97 bioavailability studies
    • Manach C, Williamson G, Morand C, et al. (2005) Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 81, 230S-242S
    • (2005) Am J Clin Nutr 81 , pp. 230S-242S
    • Manach, C.1    Williamson, G.2    Morand, C.3
  • 129
    • 3042696744 scopus 로고    scopus 로고
    • How should we assess the effects of exposure to dietary polyphenols in vitro
    • Kroon PA, Clifford MN, Crozier A, et al. (2004) How should we assess the effects of exposure to dietary polyphenols in vitro? Am J Clin Nutr 80, 15-21
    • (2004) Am J Clin Nutr , vol.80 , pp. 15-21
    • Kroon, P.A.1    Clifford, M.N.2    Crozier, A.3
  • 130
    • 79953253799 scopus 로고    scopus 로고
    • Glucose-induced endoplasmic reticulum stress is independent of oxidative stress: A mechanistic explanation for the failure of antioxidant therapy in diabetes
    • Mooradian AD &Haas MJ (2011) Glucose-induced endoplasmic reticulum stress is independent of oxidative stress: a mechanistic explanation for the failure of antioxidant therapy in diabetes. Free Radic Biol Med 50, 1140-1143
    • (2011) Free Radic Biol Med , vol.50 , pp. 1140-1143
    • Mooradian, A.D.1    Haas, M.J.2
  • 131
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • Alderton WK, Cooper CE &Knowles RG (2001) Nitric oxide synthases: structure, function and inhibition. Biochem J 357, 593-615
    • (2001) Biochem J , vol.357 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 132
    • 33846392950 scopus 로고    scopus 로고
    • Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation
    • Mount PF, Kemp BE &Power DA (2007) Regulation of endothelial and myocardial NO synthesis by multi-site eNOS phosphorylation. J Mol Cell Cardiol 42, 271-279
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 271-279
    • Mount, P.F.1    Kemp, B.E.2    Power, D.A.3
  • 133
    • 84883780569 scopus 로고    scopus 로고
    • Acute exercise induce endothelial nitric oxide synthase phosphorylation via Akt and AMP-activated protein kinase in aorta of rats: Role of reactive oxygen species
    • Barbosa VA, Luciano TF, Marques SO, et al. (2013) Acute exercise induce endothelial nitric oxide synthase phosphorylation via Akt and AMP-activated protein kinase in aorta of rats: role of reactive oxygen species. Int J Cardiol 167, 2983-2988
    • (2013) J Cardiol , vol.167 , pp. 2983-2988
    • Barbosa, V.A.1    Luciano, T.F.2    Marques, S.O.3
  • 134
  • 135
    • 9144222572 scopus 로고    scopus 로고
    • G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells
    • Federici M, Pandolfi A, De Filippis EA, et al. (2004) G972R IRS-1 variant impairs insulin regulation of endothelial nitric oxide synthase in cultured human endothelial cells. Circulation 109, 399-405
    • (2004) Circulation , vol.109 , pp. 399-405
    • Federici, M.1    Pandolfi, A.2    De Filippis, E.A.3
  • 136
    • 0032719024 scopus 로고    scopus 로고
    • Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
    • Jiang ZY, Lin YW, Clemont A, et al. (1999) Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats. J Clin Invest 104, 447-457
    • (1999) J Clin Invest , vol.104 , pp. 447-457
    • Jiang, Z.Y.1    Lin, Y.W.2    Clemont, A.3
  • 137
    • 17744364508 scopus 로고    scopus 로고
    • Effects of NADPH oxidase inhibitor in diabetic nephropathy
    • Asaba K, Tojo A, Onozato ML, et al. (2005) Effects of NADPH oxidase inhibitor in diabetic nephropathy. Kidney Int 67, 1890-1898
    • (2005) Kidney Int , vol.67 , pp. 1890-1898
    • Asaba, K.1    Tojo, A.2    Onozato, M.L.3
  • 138
    • 0029805172 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite: The good, the bad, and ugly
    • Beckman JS &Koppenol WH (1996) Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly. Am J Physiol 271, C1424-C1437
    • (1996) Am J Physiol , vol.271 , pp. C1424-C1437
    • Beckman, J.S.1    Koppenol, W.H.2
  • 139
    • 84946187178 scopus 로고    scopus 로고
    • Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities
    • Liu Z, Jiang C, Zhang J, et al. (2015) Resveratrol inhibits inflammation and ameliorates insulin resistant endothelial dysfunction via regulation of AMP-activated protein kinase and sirtuin 1 activities. J Diabetes 8, 324-335
    • (2015) J Diabetes , vol.8 , pp. 324-335
    • Liu, Z.1    Jiang, C.2    Zhang, J.3
  • 140
    • 80052322329 scopus 로고    scopus 로고
    • Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats
    • Arrick DM, Sun H, Patel KP, et al. (2011) Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats. Am J Physiol Heart Circ Physiol 301, H696-H703
    • (2011) Am J Physiol Heart Circ Physiol , vol.301 , pp. H696-H703
    • Arrick, D.M.1    Sun, H.2    Patel, K.P.3
  • 141
    • 34249666141 scopus 로고    scopus 로고
    • Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas
    • Machha A, Achike FI, Mustafa AM, et al. (2007) Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas. Nitric Oxide 16, 442-447
    • (2007) Nitric Oxide , vol.16 , pp. 442-447
    • Machha, A.1    Achike, F.I.2    Mustafa, A.M.3
  • 142
    • 84907466106 scopus 로고    scopus 로고
    • Quercetin protects against high glucose-induced damage in bone marrow-derived endothelial progenitor cells
    • Zhao LR, Du YJ, Chen L, et al. (2014) Quercetin protects against high glucose-induced damage in bone marrow-derived endothelial progenitor cells. Int J Mol Med 34, 1025-1031
    • (2014) J Mol Med , vol.34 , pp. 1025-1031
    • Zhao, L.R.1    Du, Y.J.2    Chen, L.3
  • 143
    • 84859405175 scopus 로고    scopus 로고
    • Quercetin induces rapid eNOS phosphorylation and vasodilation by an Akt-independent and PKA-dependent mechanism
    • Li PG, Sun L, Han X, et al. (2012) Quercetin induces rapid eNOS phosphorylation and vasodilation by an Akt-independent and PKA-dependent mechanism. Pharmacology 89, 220-228
    • (2012) Pharmacology , vol.89 , pp. 220-228
    • Li, P.G.1    Sun, L.2    Han, X.3
  • 144
    • 84866984649 scopus 로고    scopus 로고
    • Propyl gallate plays a nephroprotective role in early stage of diabetic nephropathy associated with suppression of glomerular endothelial cell proliferation and angiogenesis
    • Tian S, Tang J, Liu H, et al. (2012) Propyl gallate plays a nephroprotective role in early stage of diabetic nephropathy associated with suppression of glomerular endothelial cell proliferation and angiogenesis. Exp Diabetes Res 2012, 209567
    • (2012) Exp Diabetes Res , vol.2012 , pp. 209567
    • Tian, S.1    Tang, J.2    Liu, H.3
  • 145
    • 79960288645 scopus 로고    scopus 로고
    • Imbalance of glomerular VEGF-NO axis in diabetic rats: Prevention by chronic therapy with propyl gallate
    • Tian S, Gan Y, Li J, et al. (2011) Imbalance of glomerular VEGF-NO axis in diabetic rats: prevention by chronic therapy with propyl gallate. J Nephrol 24, 499-506
    • (2011) J Nephrol , vol.24 , pp. 499-506
    • Tian, S.1    Gan, Y.2    Li, J.3
  • 146
    • 84872060269 scopus 로고    scopus 로고
    • Chronic administration of daidzein, a soybean isoflavone, improves endothelial dysfunction and attenuates oxidative stress in streptozotocin-induced diabetic rats
    • Roghani M, Vaez Mahdavi MR, Jalali-Nadoushan MR, et al. (2013) Chronic administration of daidzein, a soybean isoflavone, improves endothelial dysfunction and attenuates oxidative stress in streptozotocin-induced diabetic rats. Phytother Res 27, 112-117
    • (2013) Phytother Res , vol.27 , pp. 112-117
    • Roghani, M.1    Vaez, M.M.R.2    Jalali-Nadoushan, M.R.3
  • 147
    • 84906959745 scopus 로고    scopus 로고
    • Ferulic acid combined with astragaloside IV protects against vascular endothelial dysfunction in diabetic rats
    • Yin Y, Qi F, Song Z, et al. (2014) Ferulic acid combined with astragaloside IV protects against vascular endothelial dysfunction in diabetic rats. Biosci Trends 8, 217-226
    • (2014) Biosci Trends , vol.8 , pp. 217-226
    • Yin, Y.1    Qi, F.2    Song, Z.3
  • 148
    • 79955655412 scopus 로고    scopus 로고
    • Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome
    • Rizza S, Muniyappa R, Iantorno M, et al. (2011) Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome. J Clin Endocrinol Metab 96, E782-E792
    • (2011) J Clin Endocrinol Metab , vol.96 , pp. E782-E792
    • Rizza, S.1    Muniyappa, R.2    Iantorno, M.3
  • 149
    • 84890411632 scopus 로고    scopus 로고
    • Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction
    • Jang HJ, Ridgeway SD &Kim JA (2013) Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction. Am J Physiol Endocrinol Metab 305, E1444-E1451
    • (2013) Am J Physiol Endocrinol Metab , vol.305 , pp. E1444-E1451
    • Jang, H.J.1    Ridgeway, S.D.2    Kim, J.A.3
  • 150
    • 84879804349 scopus 로고    scopus 로고
    • Alpha-linolenic acid exerts an endothelial protective effect against high glucose injury via PI3K/Akt pathway
    • Zhang W, Li R, Li J, et al. (2013) Alpha-linolenic acid exerts an endothelial protective effect against high glucose injury via PI3K/Akt pathway. PLOS ONE 8, e68489
    • (2013) PLOS ONE , vol.8 , pp. e68489
    • Zhang, W.1    Li, R.2    Li, J.3
  • 151
    • 84895813974 scopus 로고    scopus 로고
    • Catechin averts experimental diabetes mellitus-induced vascular endothelial structural and functional abnormalities
    • Bhardwaj P, Khanna D &Balakumar P (2014) Catechin averts experimental diabetes mellitus-induced vascular endothelial structural and functional abnormalities. Cardiovasc Toxicol 14, 41-51
    • (2014) Cardiovasc Toxicol , vol.14 , pp. 41-51
    • Bhardwaj, P.1    Khanna, D.2    Balakumar, P.3
  • 152
    • 33745133405 scopus 로고    scopus 로고
    • Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level
    • Tang WJ, Hu CP, Chen MF, et al. (2006) Epigallocatechin gallate preserves endothelial function by reducing the endogenous nitric oxide synthase inhibitor level. Can J Physiol Pharmacol 84, 163-171
    • (2006) Can J Physiol Pharmacol , vol.84 , pp. 163-171
    • Tang, W.J.1    Hu, C.P.2    Chen, M.F.3
  • 153
    • 79960275495 scopus 로고    scopus 로고
    • Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice
    • Li Volti G, Salomone S, Sorrenti V, et al. (2011) Effect of silibinin on endothelial dysfunction and ADMA levels in obese diabetic mice. Cardiovasc Diabetol 10, 62
    • (2011) Cardiovasc Diabetol , vol.10 , pp. 62
    • Li Volti, G.1    Salomone, S.2    Sorrenti, V.3
  • 154
    • 84893849206 scopus 로고    scopus 로고
    • Berberine protects against palmitate-induced endothelial dysfunction: Involvements of upregulation of AMPK and eNOS and downregulation of NOX4
    • Zhang M, Wang CM, Li J, et al. (2013) Berberine protects against palmitate-induced endothelial dysfunction: involvements of upregulation of AMPK and eNOS and downregulation of NOX4. Mediators Inflamm 2013, 260464
    • (2013) Mediators Inflamm , vol.2013 , pp. 260464
    • Zhang, M.1    Wang, C.M.2    Li, J.3
  • 155
    • 66249092436 scopus 로고    scopus 로고
    • Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase
    • Wang Y, Huang Y, Lam KS, et al. (2009) Berberine prevents hyperglycemia-induced endothelial injury and enhances vasodilatation via adenosine monophosphate-activated protein kinase and endothelial nitric oxide synthase. Cardiovasc Res 82, 484-492
    • (2009) Cardiovasc Res , vol.82 , pp. 484-492
    • Wang, Y.1    Huang, Y.2    Lam, K.S.3
  • 156
    • 0034979273 scopus 로고    scopus 로고
    • Role of vascular endothelial growth factor in regulation of physiological angiogenesis
    • Ferrara N (2001) Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am J Physiol Cell Physiol 280, C1358-C1366
    • (2001) Am J Physiol Cell Physiol , vol.280 , pp. C1358-C1366
    • Ferrara, N.1
  • 157
    • 55849126672 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and diabetic complications
    • Wirostko B, Wong TY &Simo R (2008) Vascular endothelial growth factor and diabetic complications. Prog Retin Eye Res 27, 608-621
    • (2008) Prog Retin Eye Res , vol.27 , pp. 608-621
    • Wirostko, B.1    Wong, T.Y.2    Simo, R.3
  • 158
    • 49349103253 scopus 로고    scopus 로고
    • Intravitreous anti-VEGF for diabetic retinopathy: Hopes and fears for a new therapeutic strategy
    • Simo R &Hernandez C (2008) Intravitreous anti-VEGF for diabetic retinopathy: hopes and fears for a new therapeutic strategy. Diabetologia 51, 1574-1580
    • (2008) Diabetologia , vol.51 , pp. 1574-1580
    • Simo, R.1    Hernandez, C.2
  • 159
    • 2442707596 scopus 로고    scopus 로고
    • The role of vascular endothelial growth factor (VEGF) in renal pathophysiology
    • Schrijvers BF, Flyvbjerg A &De Vriese AS (2004) The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Kidney Int 65, 2003-2017
    • (2004) Kidney Int , vol.65 , pp. 2003-2017
    • Schrijvers, B.F.1    Flyvbjerg, A.2    De Vriese, A.S.3
  • 160
    • 67650236579 scopus 로고    scopus 로고
    • Abnormal angiogenesis in diabetic nephropathy
    • Nakagawa T, Kosugi T, Haneda M, et al. (2009) Abnormal angiogenesis in diabetic nephropathy. Diabetes 58, 1471-1478
    • (2009) Diabetes , vol.58 , pp. 1471-1478
    • Nakagawa, T.1    Kosugi, T.2    Haneda, M.3
  • 161
    • 20244378531 scopus 로고    scopus 로고
    • Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: Restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor
    • Yoon YS, Uchida S, Masuo O, et al. (2005) Progressive attenuation of myocardial vascular endothelial growth factor expression is a seminal event in diabetic cardiomyopathy: restoration of microvascular homeostasis and recovery of cardiac function in diabetic cardiomyopathy after replenishment of local vascular endothelial growth factor. Circulation 111, 2073-2085
    • (2005) Circulation , vol.111 , pp. 2073-2085
    • Yoon, Y.S.1    Uchida, S.2    Masuo, O.3
  • 162
    • 84877344678 scopus 로고    scopus 로고
    • Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies
    • Verheyen A, Peeraer E, Lambrechts D, et al. (2013) Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies. Neuroscience 244, 77-89
    • (2013) Neuroscience , vol.244 , pp. 77-89
    • Verheyen, A.1    Peeraer, E.2    Lambrechts, D.3
  • 163
    • 34249294557 scopus 로고    scopus 로고
    • Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition
    • Verheul HM &Pinedo HM (2007) Possible molecular mechanisms involved in the toxicity of angiogenesis inhibition. Nat Rev Cancer 7, 475-485
    • (2007) Nat Rev Cancer , vol.7 , pp. 475-485
    • Verheul, H.M.1    Pinedo, H.M.2
  • 164
    • 34547505136 scopus 로고    scopus 로고
    • Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina
    • Mrudula T, Suryanarayana P, Srinivas PN, et al. (2007) Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina. Biochem Biophys Res Commun 361, 528-532
    • (2007) Biochem Biophys Res Commun , vol.361 , pp. 528-532
    • Mrudula, T.1    Suryanarayana, P.2    Srinivas, P.N.3
  • 165
    • 34247542013 scopus 로고    scopus 로고
    • Effects of curcumin on retinal oxidative stress and inflammation in diabetes
    • Kowluru RA &Kanwar M (2007) Effects of curcumin on retinal oxidative stress and inflammation in diabetes. Nutr Metab (Lond) 4, 8
    • (2007) Nutr Metab (Lond) , vol.4 , pp. 8
    • Kowluru, R.A.1    Kanwar, M.2
  • 166
    • 79952274286 scopus 로고    scopus 로고
    • Effect of curcumin on vascular endothelial growth factor expression in diabetic mice kidney induced by streptozotocin
    • Sawatpanich T, Petpiboolthai H, Punyarachun B, et al. (2010) Effect of curcumin on vascular endothelial growth factor expression in diabetic mice kidney induced by streptozotocin. J Med Assoc Thai 93, Suppl. 2, S1-S8
    • (2010) J Med Assoc Thai , vol.93 , pp. S1-S8
    • Sawatpanich, T.1    Petpiboolthai, H.2    Punyarachun, B.3
  • 167
    • 84877804288 scopus 로고    scopus 로고
    • Chlorogenic acid decreases retinal vascular hyperpermeability in diabetic rat model
    • Shin JY, Sohn J &Park KH (2013) Chlorogenic acid decreases retinal vascular hyperpermeability in diabetic rat model. J Korean Med Sci 28, 608-613
    • (2013) J Korean Med Sci , vol.28 , pp. 608-613
    • Shin, J.Y.1    Sohn, J.2    Park, K.H.3
  • 168
    • 1642433345 scopus 로고    scopus 로고
    • Opposing effect of angiopoietin-1 on VEGF-mediated disruption of endothelial cell-cell interactions requires activation of PKC beta
    • Wang Y, Pampou S, Fujikawa K, et al. (2004) Opposing effect of angiopoietin-1 on VEGF-mediated disruption of endothelial cell-cell interactions requires activation of PKC beta. J Cell Physiol 198, 53-61
    • (2004) J Cell Physiol , vol.198 , pp. 53-61
    • Wang, Y.1    Pampou, S.2    Fujikawa, K.3
  • 169
    • 33744734628 scopus 로고    scopus 로고
    • Effect of curcumin on proliferation of human retinal endothelial cells under in vitro conditions
    • Premanand C, Rema M, Sameer MZ, et al. (2006) Effect of curcumin on proliferation of human retinal endothelial cells under in vitro conditions. Invest Ophthalmol Vis Sci 47, 2179-2184
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2179-2184
    • Premanand, C.1    Rema, M.2    Sameer, M.Z.3
  • 170
    • 84903553388 scopus 로고    scopus 로고
    • Paeonol inhibits proliferation of vascular smooth muscle cells stimulated by high glucose via Ras-Raf-ERK1/2 signaling pathway in coculture model
    • Chen J, Dai M &Wang Y (2014) Paeonol inhibits proliferation of vascular smooth muscle cells stimulated by high glucose via Ras-Raf-ERK1/2 signaling pathway in coculture model. Evid Based Complement Alternat Med 2014, 484269
    • (2014) Evid Based Complement Alternat Med 2014 , pp. 484269
    • Chen, J.1    Dai, M.2    Wang, Y.3
  • 171
    • 44849101717 scopus 로고    scopus 로고
    • Scutellarein inhibits hypoxia-and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells
    • Gao R, Zhu BH, Tang SB, et al. (2008) Scutellarein inhibits hypoxia-and moderately-high glucose-induced proliferation and VEGF expression in human retinal endothelial cells. Acta Pharmacol Sin 29, 707-712
    • (2008) Acta Pharmacol Sin , vol.29 , pp. 707-712
    • Gao, R.1    Zhu, B.H.2    Tang, S.B.3
  • 172
    • 84879606651 scopus 로고    scopus 로고
    • Resveratrol ameliorates high-glucose-induced hyperpermeability mediated by caveolae via VEGF/KDR pathway
    • Tian C, Zhang R, Ye X, et al. (2013) Resveratrol ameliorates high-glucose-induced hyperpermeability mediated by caveolae via VEGF/KDR pathway. Genes Nutr 8, 231-239
    • (2013) Genes Nutr , vol.8 , pp. 231-239
    • Tian, C.1    Zhang, R.2    Ye, X.3
  • 173
    • 34548438399 scopus 로고    scopus 로고
    • R-(+)-alphalipoic acid inhibits endothelial cell apoptosis and proliferation: Involvement of Akt and retinoblastoma protein/E2F-1
    • Artwohl M, Muth K, Kosulin K, et al. (2007) R-(+)-alphalipoic acid inhibits endothelial cell apoptosis and proliferation: involvement of Akt and retinoblastoma protein/E2F-1. Am J Physiol Endocrinol Metab 293, E681-E689
    • (2007) Am J Physiol Endocrinol Metab , vol.293 , pp. E681-E689
    • Artwohl, M.1    Muth, K.2    Kosulin, K.3
  • 174
    • 24044438290 scopus 로고    scopus 로고
    • Angiogenesis, arteriogenesis, and diabetes: Paradigm reassessed
    • Simons M (2005) Angiogenesis, arteriogenesis, and diabetes: paradigm reassessed? J Am Coll Cardiol 46, 835-837
    • (2005) J Am Coll Cardiol , vol.46 , pp. 835-837
    • Simons, M.1
  • 175
    • 0037220689 scopus 로고    scopus 로고
    • Cellular dysfunction in the diabetic fibroblast: Impairment in migration, vascular endothelial growth factor production, and response to hypoxia
    • Lerman OZ, Galiano RD, Armour M, et al. (2003) Cellular dysfunction in the diabetic fibroblast: impairment in migration, vascular endothelial growth factor production, and response to hypoxia. Am J Pathol 162, 303-312
    • (2003) Am J Pathol , vol.162 , pp. 303-312
    • Lerman, O.Z.1    Galiano, R.D.2    Armour, M.3
  • 176
    • 33644781862 scopus 로고    scopus 로고
    • Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance
    • Naruse K, Rask-Madsen C, Takahara N, et al. (2006) Activation of vascular protein kinase C-beta inhibits Akt-dependent endothelial nitric oxide synthase function in obesity-associated insulin resistance. Diabetes 55, 691-698
    • (2006) Diabetes , vol.55 , pp. 691-698
    • Naruse, K.1    Rask-Madsen, C.2    Takahara, N.3
  • 177
    • 70350528625 scopus 로고    scopus 로고
    • Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice
    • Park CW, Kim HW, Lim JH, et al. (2009) Vascular endothelial growth factor inhibition by dRK6 causes endothelial apoptosis, fibrosis, and inflammation in the heart via the Akt/eNOS axis in db/db mice. Diabetes 58, 2666-2676
    • (2009) Diabetes , vol.58 , pp. 2666-2676
    • Park, C.W.1    Kim, H.W.2    Lim, J.H.3
  • 178
    • 84890623266 scopus 로고    scopus 로고
    • High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt
    • Nakamura N, Naruse K, Kobayashi Y, et al. (2011) High glucose impairs the proliferation and increases the apoptosis of endothelial progenitor cells by suppression of Akt. J Diabetes Investig 2, 262-270
    • (2011) J Diabetes Investig , vol.2 , pp. 262-270
    • Nakamura, N.1    Naruse, K.2    Kobayashi, Y.3
  • 179
    • 84865709126 scopus 로고    scopus 로고
    • VEGF and podocytes in diabetic nephropathy
    • Tufro A &Veron D (2012) VEGF and podocytes in diabetic nephropathy. Semin Nephrol 32, 385-393
    • (2012) Semin Nephrol , vol.32 , pp. 385-393
    • Tufro, A.1    Veron, D.2
  • 180
    • 53849113943 scopus 로고    scopus 로고
    • Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose
    • Yang Z, Mo X, Gong Q, et al. (2008) Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose. Apoptosis 13, 1331-1343
    • (2008) Apoptosis , vol.13 , pp. 1331-1343
    • Yang, Z.1    Mo, X.2    Gong, Q.3
  • 181
    • 84899758312 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/ db mice
    • Yang KS, Lim JH, Kim TW, et al. (2014) Vascular endothelial growth factor-receptor 1 inhibition aggravates diabetic nephropathy through eNOS signaling pathway in db/ db mice. PLOS ONE 9, e94540
    • (2014) PLOS ONE , vol.9 , pp. e94540
    • Yang, K.S.1    Lim, J.H.2    Kim, T.W.3
  • 182
    • 84893774957 scopus 로고    scopus 로고
    • Uncoupling of VEGF with endothelial NO as a potential mechanism for abnormal angiogenesis in the diabetic nephropathy
    • Nakagawa T, Sato W, Kosugi T, et al. (2013) Uncoupling of VEGF with endothelial NO as a potential mechanism for abnormal angiogenesis in the diabetic nephropathy. J Diabetes Res 2013, 184539
    • (2013) J Diabetes Res , vol.2013 , pp. 184539
    • Nakagawa, T.1    Sato, W.2    Kosugi, T.3
  • 183
    • 80855139444 scopus 로고    scopus 로고
    • Protein quality control, retention, and degradation at the endoplasmic reticulum
    • Benyair R, Ron E &Lederkremer GZ (2011) Protein quality control, retention, and degradation at the endoplasmic reticulum. Int Rev Cell Mol Biol 292, 197-280
    • (2011) Rev Cell Mol Biol , vol.292 , pp. 197-280
    • Benyair, R.1    Ron, E.2    Lederkremer, G.Z.3
  • 184
    • 45549103421 scopus 로고    scopus 로고
    • AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response
    • Luo D, He Y, Zhang H, et al. (2008) AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem 283, 11905-11912
    • (2008) J Biol Chem , vol.283 , pp. 11905-11912
    • Luo, D.1    He, Y.2    Zhang, H.3
  • 185
    • 34249276389 scopus 로고    scopus 로고
    • High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory
    • Gharavi NM, Gargalovic PS, Chang I, et al. (2007) High-density lipoprotein modulates oxidized phospholipid signaling in human endothelial cells from proinflammatory to anti-inflammatory. Arterioscler Thromb Vasc Biol 27, 1346-1353
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1346-1353
    • Gharavi, N.M.1    Gargalovic, P.S.2    Chang, I.3
  • 186
    • 0033780610 scopus 로고    scopus 로고
    • A regulatory link between ER-associated protein degradation and the unfolded-protein response
    • Friedlander R, Jarosch E, Urban J, et al. (2000) A regulatory link between ER-associated protein degradation and the unfolded-protein response. Nat Cell Biol 2, 379-384
    • (2000) Nat Cell Biol , vol.2 , pp. 379-384
    • Friedlander, R.1    Jarosch, E.2    Urban, J.3
  • 187
    • 84859817850 scopus 로고    scopus 로고
    • Sensing endoplasmic reticulum stress
    • Parmar VM &Schroder M (2012) Sensing endoplasmic reticulum stress. Adv Exp Med Biol 738, 153-168
    • (2012) Adv Exp Med Biol , vol.738 , pp. 153-168
    • Parmar, V.M.1    Schroder, M.2
  • 188
    • 0035957929 scopus 로고    scopus 로고
    • Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress
    • Yoneda T, Imaizumi K, Oono K, et al. (2001) Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stress. J Biol Chem 276, 13935-13940
    • (2001) J Biol Chem , vol.276 , pp. 13935-13940
    • Yoneda, T.1    Imaizumi, K.2    Oono, K.3
  • 189
    • 26444442450 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress: Cell life and death decisions
    • Xu C, Bailly-Maitre B &Reed JC (2005) Endoplasmic reticulum stress: cell life and death decisions. J Clin Invest 115, 2656-2664
    • (2005) J Clin Invest , vol.115 , pp. 2656-2664
    • Xu, C.1    Bailly-Maitre, B.2    Reed, J.C.3
  • 190
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, et al. (2001) Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state. Mol Cell Biol 21, 1249-1259
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3
  • 191
    • 84866135183 scopus 로고    scopus 로고
    • Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes
    • Chen Y, Wang JJ, Li J, et al. (2012) Activating transcription factor 4 mediates hyperglycaemia-induced endothelial inflammation and retinal vascular leakage through activation of STAT3 in a mouse model of type 1 diabetes. Diabetologia 55, 2533-2545
    • (2012) Diabetologia , vol.55 , pp. 2533-2545
    • Chen, Y.1    Wang, J.J.2    Li, J.3
  • 192
    • 33845722716 scopus 로고    scopus 로고
    • Stress, the endoplasmic reticulum, and insulin resistance
    • Tsiotra PC &Tsigos C (2006) Stress, the endoplasmic reticulum, and insulin resistance. Ann N Y Acad Sci 1083, 63-76
    • (2006) Ann N y Acad Sci , vol.1083 , pp. 63-76
    • Tsiotra, P.C.1    Tsigos, C.2
  • 193
    • 84901461838 scopus 로고    scopus 로고
    • PERK pathway are involved in NO-induced apoptosis in endothelial cells cocultured with RPE under high glucose conditions
    • Zhang X, Fu Y, Xu X, et al. (2014) PERK pathway are involved in NO-induced apoptosis in endothelial cells cocultured with RPE under high glucose conditions. Nitric Oxide 40, 10-16
    • (2014) Nitric Oxide , vol.40 , pp. 10-16
    • Zhang, X.1    Fu, Y.2    Xu, X.3
  • 194
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman RJ (2002) Orchestrating the unfolded protein response in health and disease. J Clin Invest 110, 1389-1398
    • (2002) J Clin Invest , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 195
    • 67349269219 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy
    • Li J, Wang JJ, Yu Q, et al. (2009) Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy. FEBS Lett 583, 1521-1527
    • (2009) FEBS Lett , vol.583 , pp. 1521-1527
    • Li, J.1    Wang, J.J.2    Yu, Q.3
  • 196
    • 78149262655 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in age-related macular degeneration: Trigger for neovascularization
    • Salminen A, Kauppinen A, Hyttinen JM, et al. (2010) Endoplasmic reticulum stress in age-related macular degeneration: trigger for neovascularization. Mol Med 16, 535-542
    • (2010) Mol Med , vol.16 , pp. 535-542
    • Salminen, A.1    Kauppinen, A.2    Hyttinen, J.M.3
  • 197
    • 84865609561 scopus 로고    scopus 로고
    • Novel targets against retinal angiogenesis in diabetic retinopathy
    • Wang S, Park JK &Duh EJ (2012) Novel targets against retinal angiogenesis in diabetic retinopathy. Curr Diab Rep 12, 355-363
    • (2012) Curr Diab Rep , vol.12 , pp. 355-363
    • Wang, S.1    Park, J.K.2    Duh, E.J.3
  • 198
    • 74449092406 scopus 로고    scopus 로고
    • Effects of antioxidants on glucose-induced oxidative stress and endoplasmic reticulum stress in endothelial cells
    • Sheikh-Ali M, Sultan S, Alamir AR, et al. (2010) Effects of antioxidants on glucose-induced oxidative stress and endoplasmic reticulum stress in endothelial cells. Diabetes Res Clin Pract 87, 161-166
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 161-166
    • Sheikh-Ali, M.1    Sultan, S.2    Alamir, A.R.3
  • 199
    • 84921733825 scopus 로고    scopus 로고
    • Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/ NLRP3 inflammasome activation with regulation of AMPK in endothelial cells
    • Song J, Li J, Hou F, et al. (2015) Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/ NLRP3 inflammasome activation with regulation of AMPK in endothelial cells. Metabolism 64, 428-437
    • (2015) Metabolism , vol.64 , pp. 428-437
    • Song, J.1    Li, J.2    Hou, F.3
  • 200
    • 84936891896 scopus 로고    scopus 로고
    • Inflammasomes: Mechanism of action, role in disease, and therapeutics
    • Guo H, Callaway JB &Ting JP (2015) Inflammasomes: mechanism of action, role in disease, and therapeutics. Nat Med 21, 677-687
    • (2015) Nat Med , vol.21 , pp. 677-687
    • Guo, H.1    Callaway, J.B.2    Ting, J.P.3
  • 201
    • 77950343791 scopus 로고    scopus 로고
    • Pattern recognition receptors and inflammation
    • Takeuchi O &Akira S (2010) Pattern recognition receptors and inflammation. Cell 140, 805-820
    • (2010) Cell , vol.140 , pp. 805-820
    • Takeuchi, O.1    Akira, S.2
  • 202
    • 84893663061 scopus 로고    scopus 로고
    • Thioredoxininteracting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet
    • Mohamed IN, Hafez SS, Fairaq A, et al. (2014) Thioredoxininteracting protein is required for endothelial NLRP3 inflammasome activation and cell death in a rat model of high-fat diet. Diabetologia 57, 413-423
    • (2014) Diabetologia , vol.57 , pp. 413-423
    • Mohamed, I.N.1    Hafez, S.S.2    Fairaq, A.3
  • 203
    • 84918802345 scopus 로고    scopus 로고
    • Quercetin, luteolin and epigallocatechin gallate alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with regulation of AMPK in endothelial cells
    • Wu J, Xu X, Li Y, et al. (2014) Quercetin, luteolin and epigallocatechin gallate alleviate TXNIP and NLRP3-mediated inflammation and apoptosis with regulation of AMPK in endothelial cells. Eur J Pharmacol 745, 59-68
    • (2014) Eur J Pharmacol , vol.745 , pp. 59-68
    • Wu, J.1    Xu, X.2    Li, Y.3
  • 204
    • 84935831513 scopus 로고    scopus 로고
    • Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner
    • Li Y, Yang J, Chen MH, et al. (2015) Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner. Pharmacol Res 99, 101-115
    • (2015) Pharmacol Res , vol.99 , pp. 101-115
    • Li, Y.1    Yang, J.2    Chen, M.H.3
  • 205
    • 84929165139 scopus 로고    scopus 로고
    • Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium
    • Zhao Y, Li Q, Zhao W, et al. (2015) Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium. J Ethnopharmacol 169, 210-218
    • (2015) J Ethnopharmacol , vol.169 , pp. 210-218
    • Zhao, Y.1    Li, Q.2    Zhao, W.3
  • 206
    • 61349114196 scopus 로고    scopus 로고
    • Protective effect of quercetin on ER stress caused by calcium dynamics dysregulation in intestinal epithelial cells
    • Natsume Y, Ito S, Satsu H, et al. (2009) Protective effect of quercetin on ER stress caused by calcium dynamics dysregulation in intestinal epithelial cells. Toxicology 258, 164-175
    • (2009) Toxicology , vol.258 , pp. 164-175
    • Natsume, Y.1    Ito, S.2    Satsu, H.3
  • 207
    • 79961054838 scopus 로고    scopus 로고
    • A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin
    • Reiling JH, Clish CB, Carette JE, et al. (2011) A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin. Proc Natl Acad Sci U S A 108, 11756-11765
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 11756-11765
    • Reiling, J.H.1    Clish, C.B.2    Carette, J.E.3
  • 208
    • 33748789479 scopus 로고    scopus 로고
    • Mediators of endoplasmic reticulum stress-induced apoptosis
    • Szegezdi E, Logue SE, Gorman AM, et al. (2006) Mediators of endoplasmic reticulum stress-induced apoptosis. EMBO Rep 7, 880-885
    • (2006) EMBO Rep , vol.7 , pp. 880-885
    • Szegezdi, E.1    Logue, S.E.2    Gorman, A.M.3
  • 209
    • 84900028878 scopus 로고    scopus 로고
    • Quercetin ameliorates tunicamycin-induced endoplasmic reticulum stress in endothelial cells
    • Suganya N, Bhakkiyalakshmi E, Suriyanarayanan S, et al. (2014) Quercetin ameliorates tunicamycin-induced endoplasmic reticulum stress in endothelial cells. Cell Prolif 47, 231-240
    • (2014) Cell Prolif , vol.47 , pp. 231-240
    • Suganya, N.1    Bhakkiyalakshmi, E.2    Suriyanarayanan, S.3
  • 210
    • 19444363980 scopus 로고    scopus 로고
    • Shock, inflammation and PARP
    • Cuzzocrea S (2005) Shock, inflammation and PARP. Pharmacol Res 52, 72-82
    • (2005) Pharmacol Res , vol.52 , pp. 72-82
    • Cuzzocrea, S.1
  • 211
    • 33644814524 scopus 로고    scopus 로고
    • Resveratrol decreases calcium sensitivity of vascular smooth muscle and enhances cytosolic calcium increase in endothelium
    • Buluc M &Demirel-Yilmaz E (2006) Resveratrol decreases calcium sensitivity of vascular smooth muscle and enhances cytosolic calcium increase in endothelium. Vascul Pharmacol 44, 231-237
    • (2006) Vascul Pharmacol , vol.44 , pp. 231-237
    • Buluc, M.1    Demirel-Yilmaz, E.2
  • 212
    • 84862853852 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in retinal vascular degeneration: Protective role of resveratrol
    • Li C, Wang L, Huang K, et al. (2012) Endoplasmic reticulum stress in retinal vascular degeneration: protective role of resveratrol. Invest Ophthalmol Vis Sci 53, 3241-3249
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 3241-3249
    • Li, C.1    Wang, L.2    Huang, K.3
  • 213
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemiainduced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • Du XL, Edelstein D, Rossetti L, et al. (2000) Hyperglycemiainduced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proc Natl Acad Sci U S A 97, 12222-12226
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 12222-12226
    • Du, X.L.1    Edelstein, D.2    Rossetti, L.3
  • 214
    • 0142085746 scopus 로고    scopus 로고
    • Physiological genomics of human arteries: Quantitative relationship between gene expression and arterial stiffness
    • Durier S, Fassot C, Laurent S, et al. (2003) Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness. Circulation 108, 1845-1851
    • (2003) Circulation , vol.108 , pp. 1845-1851
    • Durier, S.1    Fassot, C.2    Laurent, S.3
  • 215
    • 62349116866 scopus 로고    scopus 로고
    • Vascular NAD(P)H oxidase activation in diabetes: A double-edged sword in redox signalling
    • Gao L &Mann GE (2009) Vascular NAD(P)H oxidase activation in diabetes: a double-edged sword in redox signalling. Cardiovasc Res 82, 9-20
    • (2009) Cardiovasc Res , vol.82 , pp. 9-20
    • Gao, L.1    Mann, G.E.2
  • 216
    • 5644247979 scopus 로고    scopus 로고
    • Endotheliumrestricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction
    • Amiri F, Virdis A, Neves MF, et al. (2004) Endotheliumrestricted overexpression of human endothelin-1 causes vascular remodeling and endothelial dysfunction. Circulation 110, 2233-2240
    • (2004) Circulation , vol.110 , pp. 2233-2240
    • Amiri, F.1    Virdis, A.2    Neves, M.F.3
  • 217
    • 80655125179 scopus 로고    scopus 로고
    • Blocking NF-kappaB: An inflammatory issue
    • Rahman A &Fazal F (2011) Blocking NF-kappaB: an inflammatory issue. Proc Am Thorac Soc 8, 497-503
    • (2011) Proc Am Thorac Soc , vol.8 , pp. 497-503
    • Rahman, A.1    Fazal, F.2
  • 218
    • 11844269840 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappaB and IkappaB proteins: Implications in cancer and inflammation
    • Viatour P, Merville MP, Bours V, et al. (2005) Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem Sci 30, 43-52
    • (2005) Trends Biochem Sci , vol.30 , pp. 43-52
    • Viatour, P.1    Merville, M.P.2    Bours, V.3
  • 219
    • 84893415113 scopus 로고    scopus 로고
    • New paradigms in inflammatory signaling in vascular endothelial cells
    • Xiao L, Liu Y &Wang N (2014) New paradigms in inflammatory signaling in vascular endothelial cells. Am J Physiol Heart Circ Physiol 306, H317-H325
    • (2014) Am J Physiol Heart Circ Physiol , vol.306 , pp. H317-H325
    • Xiao, L.1    Liu, Y.2    Wang, N.3
  • 220
    • 0038069126 scopus 로고    scopus 로고
    • High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells
    • Takaishi H, Taniguchi T, Takahashi A, et al. (2003) High glucose accelerates MCP-1 production via p38 MAPK in vascular endothelial cells. Biochem Biophys Res Commun 305, 122-128
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 122-128
    • Takaishi, H.1    Taniguchi, T.2    Takahashi, A.3
  • 221
    • 33745324596 scopus 로고    scopus 로고
    • Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes
    • Natali A, Toschi E, Baldeweg S, et al. (2006) Clustering of insulin resistance with vascular dysfunction and low-grade inflammation in type 2 diabetes. Diabetes 55, 1133-1140
    • (2006) Diabetes , vol.55 , pp. 1133-1140
    • Natali, A.1    Toschi, E.2    Baldeweg, S.3
  • 222
    • 83655172387 scopus 로고    scopus 로고
    • The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: An update
    • Zhang H, Dellsperger KC &Zhang C (2012) The link between metabolic abnormalities and endothelial dysfunction in type 2 diabetes: an update. Basic Res Cardiol 107, 237
    • (2012) Basic Res Cardiol , vol.107 , pp. 237
    • Zhang, H.1    Dellsperger, K.C.2    Zhang, C.3
  • 223
    • 33749365317 scopus 로고    scopus 로고
    • Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: Role of NF-kappaB inhibition
    • Csiszar A, Smith K, Labinskyy N, et al. (2006) Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol 291, H1694-H1699
    • (2006) Am J Physiol Heart Circ Physiol , vol.291 , pp. H1694-H1699
    • Csiszar, A.1    Smith, K.2    Labinskyy, N.3
  • 224
    • 84900814151 scopus 로고    scopus 로고
    • Pleiotropic beneficial effects of epigallocatechin gallate, quercetin and delphinidin on cardiovascular diseases associated with endothelial dysfunction
    • Dayoub O, Andriantsitohaina R &Clere N (2013) Pleiotropic beneficial effects of epigallocatechin gallate, quercetin and delphinidin on cardiovascular diseases associated with endothelial dysfunction. Cardiovasc Hematol Agents Med Chem 11, 249-264
    • (2013) Cardiovasc Hematol Agents Med Chem , vol.11 , pp. 249-264
    • Dayoub, O.1    Andriantsitohaina, R.2    Clere, N.3
  • 225
    • 84904089052 scopus 로고    scopus 로고
    • Molecular mechanisms of curcumin on diabetes-induced endothelial dysfunctions: Txnip, ICAM-1, and NOX2 expressions
    • Wongeakin N, Bhattarakosol P &Patumraj S (2014) Molecular mechanisms of curcumin on diabetes-induced endothelial dysfunctions: Txnip, ICAM-1, and NOX2 expressions. Biomed Res Int 2014, 161346
    • (2014) Biomed Res Int , vol.2014 , pp. 161346
    • Wongeakin, N.1    Bhattarakosol, P.2    Patumraj, S.3
  • 226
    • 79955008744 scopus 로고    scopus 로고
    • Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms
    • Gupta SK, Kumar B, Nag TC, et al. (2011) Curcumin prevents experimental diabetic retinopathy in rats through its hypoglycemic, antioxidant, and anti-inflammatory mechanisms. J Ocul Pharmacol Ther 27, 123-130
    • (2011) J Ocul Pharmacol Ther , vol.27 , pp. 123-130
    • Gupta, S.K.1    Kumar, B.2    Nag, T.C.3
  • 227
    • 77957765255 scopus 로고    scopus 로고
    • Curcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibition
    • Rungseesantivanon S, Thenchaisri N, Ruangvejvorachai P, et al. (2010) Curcumin supplementation could improve diabetes-induced endothelial dysfunction associated with decreased vascular superoxide production and PKC inhibition. BMC Complement Altern Med 10, 57
    • (2010) BMC Complement Altern Med , vol.10 , pp. 57
    • Rungseesantivanon, S.1    Thenchaisri, N.2    Ruangvejvorachai, P.3
  • 228
    • 84878083345 scopus 로고    scopus 로고
    • Quercetin protects against diabetes-induced exaggerated vasoconstriction in rats: Effect on low grade inflammation
    • Mahmoud MF, Hassan NA, El Bassossy HM, et al. (2013) Quercetin protects against diabetes-induced exaggerated vasoconstriction in rats: effect on low grade inflammation. PLOS ONE 8, e63784
    • (2013) PLOS ONE , vol.8 , pp. e63784
    • Mahmoud, M.F.1    Hassan, N.A.2    El Bassossy, H.M.3
  • 229
    • 73949154005 scopus 로고    scopus 로고
    • Dietary flavonoid apigenin inhibits high glucose and tumor necrosis factor alpha-induced adhesion molecule expression in human endothelial cells
    • Yamagata K, Miyashita A, Matsufuji H, et al. (2010) Dietary flavonoid apigenin inhibits high glucose and tumor necrosis factor alpha-induced adhesion molecule expression in human endothelial cells. J Nutr Biochem 21, 116-124
    • (2010) J Nutr Biochem , vol.21 , pp. 116-124
    • Yamagata, K.1    Miyashita, A.2    Matsufuji, H.3
  • 230
    • 0041358574 scopus 로고    scopus 로고
    • A novel potential therapy for diabetic nephropathy and vascular complications: Protein kinase C beta inhibition
    • Tuttle KR &Anderson PW (2003) A novel potential therapy for diabetic nephropathy and vascular complications: protein kinase C beta inhibition. Am J Kidney Dis 42, 456-465
    • (2003) Am J Kidney Dis , vol.42 , pp. 456-465
    • Tuttle, K.R.1    Anderson, P.W.2
  • 231
    • 84875414702 scopus 로고    scopus 로고
    • EGCG attenuates high glucose-induced endothelial cell inflammation by suppression of PKC and NF-kappaB signaling in human umbilical vein endothelial cells
    • Yang J, Han Y, Chen C, et al. (2013) EGCG attenuates high glucose-induced endothelial cell inflammation by suppression of PKC and NF-kappaB signaling in human umbilical vein endothelial cells. Life Sci 92, 589-597
    • (2013) Life Sci , vol.92 , pp. 589-597
    • Yang, J.1    Han, Y.2    Chen, C.3
  • 232
    • 84855906093 scopus 로고    scopus 로고
    • Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells
    • Kim SW, Kim CE &Kim MH (2011) Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells. Biochem Biophys Res Commun 415, 602-607
    • (2011) Biochem Biophys Res Commun , vol.415 , pp. 602-607
    • Kim, S.W.1    Kim, C.E.2    Kim, M.H.3
  • 233
    • 84922731168 scopus 로고    scopus 로고
    • Protection of vascular endothelial cells from high glucose-induced cytotoxicity by emodin
    • Gao Y, Zhang J, Li G, et al. (2015) Protection of vascular endothelial cells from high glucose-induced cytotoxicity by emodin. Biochem Pharmacol 94, 39-45
    • (2015) Biochem Pharmacol , vol.94 , pp. 39-45
    • Gao, Y.1    Zhang, J.2    Li, G.3
  • 234
    • 84897898366 scopus 로고    scopus 로고
    • Brazilin ameliorates high glucose-induced vascular inflammation via inhibiting ROS and CAMs production in human umbilical vein endothelial cells
    • Jayakumar T, Chang CC, Lin SL, et al. (2014) Brazilin ameliorates high glucose-induced vascular inflammation via inhibiting ROS and CAMs production in human umbilical vein endothelial cells. Biomed Res Int 2014, 403703
    • (2014) Biomed Res Int , vol.2014 , pp. 403703
    • Jayakumar, T.1    Chang, C.C.2    Lin, S.L.3
  • 235
    • 84896353574 scopus 로고    scopus 로고
    • Emodin-6-O-beta-D-glucoside inhibits high-glucose-induced vascular inflammation
    • Lee W, Ku SK, Lee D, et al. (2014) Emodin-6-O-beta-D-glucoside inhibits high-glucose-induced vascular inflammation. Inflammation 37, 306-313
    • (2014) Inflammation , vol.37 , pp. 306-313
    • Lee, W.1    Ku, S.K.2    Lee, D.3
  • 236
    • 80051570204 scopus 로고    scopus 로고
    • [Naringin inhibits monocyte adhesion to high glucose-induced human umbilical vein endothelial cells]
    • Xiong Y, Wang GF, Zhang JY, et al. (2010) [Naringin inhibits monocyte adhesion to high glucose-induced human umbilical vein endothelial cells]. Nan Fang Yi Ke Da Xue Xue Bao 30, 321-325
    • (2010) Nan Fang Yi Ke da Xue Xue Bao , vol.30 , pp. 321-325
    • Xiong, Y.1    Wang, G.F.2    Zhang, J.Y.3
  • 237
    • 84906214536 scopus 로고    scopus 로고
    • Fisetin inhibits high-glucoseinduced vascular inflammation in vitro and in vivo
    • Kwak S, Ku SK &Bae JS (2014) Fisetin inhibits high-glucoseinduced vascular inflammation in vitro and in vivo. Inflamm Res 63, 779-787
    • (2014) Inflamm Res , vol.63 , pp. 779-787
    • Kwak, S.1    Ku, S.K.2    Bae, J.S.3
  • 238
    • 84937549362 scopus 로고    scopus 로고
    • Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo
    • Ku SK, Kwak S &Bae JS (2014) Orientin inhibits high glucose-induced vascular inflammation in vitro and in vivo. Inflammation 37, 2164-2173
    • (2014) Inflammation , vol.37 , pp. 2164-2173
    • Ku, S.K.1    Kwak, S.2    Bae, J.S.3
  • 239
    • 84944733950 scopus 로고    scopus 로고
    • Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo
    • Ku SK &Bae JS (2015) Baicalin, baicalein and wogonin inhibits high glucose-induced vascular inflammation in vitro and in vivo. BMB Rep 48, 519-524
    • (2015) BMB Rep , vol.48 , pp. 519-524
    • Ku, S.K.1    Bae, J.S.2
  • 240
    • 84890128149 scopus 로고    scopus 로고
    • Protective effects of chronic resveratrol treatment on vascular inflammatory injury in steptozotocin-induced type 2 diabetic rats: Role of NF-kappa B signaling
    • Zheng X, Zhu S, Chang S, et al. (2013) Protective effects of chronic resveratrol treatment on vascular inflammatory injury in steptozotocin-induced type 2 diabetic rats: role of NF-kappa B signaling. Eur J Pharmacol 720, 147-157
    • (2013) Eur J Pharmacol , vol.720 , pp. 147-157
    • Zheng, X.1    Zhu, S.2    Chang, S.3
  • 241
    • 84861149561 scopus 로고    scopus 로고
    • Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice
    • Babu PV, Si H, Fu Z, et al. (2012) Genistein prevents hyperglycemia-induced monocyte adhesion to human aortic endothelial cells through preservation of the cAMP signaling pathway and ameliorates vascular inflammation in obese diabetic mice. J Nutr 142, 724-730
    • (2012) J Nutr , vol.142 , pp. 724-730
    • Babu, P.V.1    Si, H.2    Fu, Z.3
  • 242
    • 84888841120 scopus 로고    scopus 로고
    • Membranar effects exerted in vitro by polyphenols-quercetin, epigallocatechin gallate and curcumin-on HUVEC and Jurkat cells, relevant for diabetes mellitus
    • Margina D, Gradinaru D, Manda G, et al. (2013) Membranar effects exerted in vitro by polyphenols-quercetin, epigallocatechin gallate and curcumin-on HUVEC and Jurkat cells, relevant for diabetes mellitus. Food Chem Toxicol 61, 86-93
    • (2013) Food Chem Toxicol , vol.61 , pp. 86-93
    • Margina, D.1    Gradinaru, D.2    Manda, G.3
  • 244
    • 33845442925 scopus 로고    scopus 로고
    • Mechanistic studies of the Nrf2-Keap1 signaling pathway
    • Zhang DD (2006) Mechanistic studies of the Nrf2-Keap1 signaling pathway. Drug Metab Rev 38, 769-789
    • (2006) Drug Metab Rev , vol.38 , pp. 769-789
    • Zhang, D.D.1
  • 245
    • 0037428445 scopus 로고    scopus 로고
    • Laminar flow induction of antioxidant response element-mediated genes in endothelial cells A novel anti-inflammatory mechanism
    • Chen XL, Varner SE, Rao AS, et al. (2003) Laminar flow induction of antioxidant response element-mediated genes in endothelial cells. A novel anti-inflammatory mechanism. J Biol Chem 278, 703-711
    • (2003) J Biol Chem , vol.278 , pp. 703-711
    • Chen, X.L.1    Varner, S.E.2    Rao, A.S.3
  • 246
    • 77951479702 scopus 로고    scopus 로고
    • Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: Novel point of convergence between electrophilic and unfolded protein stress pathways
    • Afonyushkin T, Oskolkova OV, Philippova M, et al. (2010) Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways. Arterioscler Thromb Vasc Biol 30, 1007-1013
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1007-1013
    • Afonyushkin, T.1    Oskolkova, O.V.2    Philippova, M.3
  • 247
    • 84937558877 scopus 로고    scopus 로고
    • Activation of nuclear factor erythroid 2-related factor 2 coordinates dimethylarginine dimethylaminohydrolase/PPAR-gamma/endothelial nitric oxide synthase pathways that enhance nitric oxide generation in human glomerular endothelial cells
    • Luo Z, Aslam S, Welch WJ, et al. (2015) Activation of nuclear factor erythroid 2-related factor 2 coordinates dimethylarginine dimethylaminohydrolase/PPAR-gamma/endothelial nitric oxide synthase pathways that enhance nitric oxide generation in human glomerular endothelial cells. Hypertension 65, 896-902
    • (2015) Hypertension , vol.65 , pp. 896-902
    • Luo, Z.1    Aslam, S.2    Welch, W.J.3
  • 248
    • 84878804327 scopus 로고    scopus 로고
    • Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy
    • Zhong Q, Mishra M &Kowluru RA (2013) Transcription factor Nrf2-mediated antioxidant defense system in the development of diabetic retinopathy. Invest Ophthalmol Vis Sci 54, 3941-3948
    • (2013) Invest Ophthalmol Vis Sci , vol.54 , pp. 3941-3948
    • Zhong, Q.1    Mishra, M.2    Kowluru, R.A.3
  • 249
    • 79955068967 scopus 로고    scopus 로고
    • Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia
    • Ungvari Z, Bailey-Downs L, Gautam T, et al. (2011) Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol 300, H1133-H1140
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. H1133-H1140
    • Ungvari, Z.1    Bailey-Downs, L.2    Gautam, T.3
  • 250
    • 1542723493 scopus 로고    scopus 로고
    • Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
    • Suh JH, Shenvi SV, Dixon BM, et al. (2004) Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci U S A 101, 3381-3386
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 3381-3386
    • Suh, J.H.1    Shenvi, S.V.2    Dixon, B.M.3
  • 251
    • 77951199503 scopus 로고    scopus 로고
    • The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy
    • Jiang T, Huang Z, Lin Y, et al. (2010) The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy. Diabetes 59, 850-860
    • (2010) Diabetes , vol.59 , pp. 850-860
    • Jiang, T.1    Huang, Z.2    Lin, Y.3
  • 252
    • 33750734665 scopus 로고    scopus 로고
    • NRF2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia-induced brain endothelial cell apoptosis
    • Okouchi M, Okayama N, Alexander JS, et al. (2006) NRF2-dependent glutamate-L-cysteine ligase catalytic subunit expression mediates insulin protection against hyperglycemia-induced brain endothelial cell apoptosis. Curr Neurovasc Res 3, 249-261
    • (2006) Curr Neurovasc Res , vol.3 , pp. 249-261
    • Okouchi, M.1    Okayama, N.2    Alexander, J.S.3
  • 253
    • 54449084867 scopus 로고    scopus 로고
    • Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice
    • Yoh K, Hirayama A, Ishizaki K, et al. (2008) Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice. Genes Cells 13, 1159-1170
    • (2008) Genes Cells , vol.13 , pp. 1159-1170
    • Yoh, K.1    Hirayama, A.2    Ishizaki, K.3
  • 254
    • 77953741269 scopus 로고    scopus 로고
    • Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2
    • Ungvari Z, Bagi Z, Feher A, et al. (2010) Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. Am J Physiol Heart Circ Physiol 299, H18-H24
    • (2010) Am J Physiol Heart Circ Physiol , vol.299 , pp. H18-H24
    • Ungvari, Z.1    Bagi, Z.2    Feher, A.3
  • 255
    • 84884306619 scopus 로고    scopus 로고
    • Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes
    • Velmurugan GV, Sundaresan NR, Gupta MP, et al. (2013) Defective Nrf2-dependent redox signalling contributes to microvascular dysfunction in type 2 diabetes. Cardiovasc Res 100, 143-150
    • (2013) Cardiovasc Res , vol.100 , pp. 143-150
    • Velmurugan, G.V.1    Sundaresan, N.R.2    Gupta, M.P.3
  • 256
    • 84933544750 scopus 로고    scopus 로고
    • Eriodictyol protects endothelial cells against oxidative stress-induced cell death through modulating ERK/Nrf2/ARE-dependent heme oxygenase-1 expression
    • Lee SE, Yang H, Son GW, et al. (2015) Eriodictyol protects endothelial cells against oxidative stress-induced cell death through modulating ERK/Nrf2/ARE-dependent heme oxygenase-1 expression. Int J Mol Sci 16, 14526-14539
    • (2015) J Mol Sci , vol.16 , pp. 14526-14539
    • Lee, S.E.1    Yang, H.2    Son, G.W.3
  • 257
    • 84882742544 scopus 로고    scopus 로고
    • Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-kappaB pathways in diabetic neuropathy
    • Ganesh Yerra V, Negi G, Sharma SS, et al. (2013) Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-kappaB pathways in diabetic neuropathy. Redox Biol 1, 394-397
    • (2013) Redox Biol , vol.1 , pp. 394-397
    • Ganesh, Y.V.1    Negi, G.2    Sharma, S.S.3
  • 258
    • 58149352893 scopus 로고    scopus 로고
    • Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease
    • Xue M, Qian Q, Adaikalakoteswari A, et al. (2008) Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes 57, 2809-2817
    • (2008) Diabetes , vol.57 , pp. 2809-2817
    • Xue, M.1    Qian, Q.2    Adaikalakoteswari, A.3
  • 259
    • 82155197554 scopus 로고    scopus 로고
    • Nrf2 and NF-kappaB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucoseinduced changes
    • Negi G, Kumar A &Sharma SS (2011) Nrf2 and NF-kappaB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucoseinduced changes. Curr Neurovasc Res 8, 294-304
    • (2011) Curr Neurovasc Res , vol.8 , pp. 294-304
    • Negi, G.1    Kumar, A.2    Sharma, S.S.3
  • 260
    • 84916918569 scopus 로고    scopus 로고
    • Curcumin-induced angiogenesis hastens wound healing in diabetic rats
    • Kant V, Gopal A, Kumar D, et al. (2015) Curcumin-induced angiogenesis hastens wound healing in diabetic rats. J Surg Res 193, 978-988
    • (2015) J Surg Res , vol.193 , pp. 978-988
    • Kant, V.1    Gopal, A.2    Kumar, D.3
  • 261
    • 84865713969 scopus 로고    scopus 로고
    • Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-kappaB-mediated mechanism
    • Babu PV, Si H &Liu D (2012) Epigallocatechin gallate reduces vascular inflammation in db/db mice possibly through an NF-kappaB-mediated mechanism. Mol Nutr Food Res 56, 1424-1432
    • (2012) Mol Nutr Food Res , vol.56 , pp. 1424-1432
    • Babu, P.V.1    Si, H.2    Liu, D.3
  • 262
    • 84891621483 scopus 로고    scopus 로고
    • Resveratrol attenuates diabetic nephropathy via modulating angiogenesis
    • Wen D, Huang X, Zhang M, et al. (2013) Resveratrol attenuates diabetic nephropathy via modulating angiogenesis. PLOS ONE 8, e82336
    • (2013) PLOS ONE , vol.8 , pp. e82336
    • Wen, D.1    Huang, X.2    Zhang, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.