메뉴 건너뛰기




Volumn 13, Issue 11, 2008, Pages 1331-1343

Critical effect of VEGF in the process of endothelial cell apoptosis induced by high glucose

Author keywords

Apoptosis; Bax; Caspase 3; Endothelial cells; Hyperglycemia; VEGF

Indexed keywords

CALCIUM; CASPASE 3; GLUCOSE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; VASCULOTROPIN;

EID: 53849113943     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0257-y     Document Type: Article
Times cited : (74)

References (51)
  • 2
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications I insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group. 10.1056/NEJM199309303291401
    • The Diabetes Control and Complications Trial Research Group 1993 The effect of intensive treatment of diabetes on the development and progression of long-term complications I insulin-dependent diabetes mellitus N Engl J Med 329 977 986 10.1056/NEJM199309303291401
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 3
    • 0021861537 scopus 로고
    • Glucose toxicity for human endothelial cells in culture: Delayed replication, disturbed cell cycle, and accelerated death
    • 10.2337/diabetes.34.7.621
    • M Lorenzi E Cagliero S Toledo 1985 Glucose toxicity for human endothelial cells in culture: delayed replication, disturbed cell cycle, and accelerated death Diabetes 34 621 627 10.2337/diabetes.34.7.621
    • (1985) Diabetes , vol.34 , pp. 621-627
    • Lorenzi, M.1    Cagliero, E.2    Toledo, S.3
  • 5
    • 0036230482 scopus 로고    scopus 로고
    • Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat
    • 10.2337/diabetes.51.4.1076
    • A Ceriello L Quagliaro M D'Amico 2002 Acute hyperglycemia induces nitrotyrosine formation and apoptosis in perfused heart from rat Diabetes 51 1076 1082 10.2337/diabetes.51.4.1076
    • (2002) Diabetes , vol.51 , pp. 1076-1082
    • Ceriello, A.1    Quagliaro, L.2    D'Amico, M.3
  • 6
    • 0034993799 scopus 로고    scopus 로고
    • Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells
    • 10.2337/diabetes.50.6.1472
    • H Nakagami R Morishita K Yamamoto 2001 Phosphorylation of p38 mitogen-activated protein kinase downstream of bax-caspase-3 pathway leads to cell death induced by high D-glucose in human endothelial cells Diabetes 50 1472 1481 10.2337/diabetes.50.6.1472
    • (2001) Diabetes , vol.50 , pp. 1472-1481
    • Nakagami, H.1    Morishita, R.2    Yamamoto, K.3
  • 7
    • 3142667690 scopus 로고    scopus 로고
    • Nerve growth factor promotes reparative angiogenesis and inhibits endothelial apoptosis in cutaneous wounds of Type 1 diabetic mice
    • 6. 10.1007/s00125-004-1414-7
    • G Graiani C Emanueli E Desortes 2004 Nerve growth factor promotes reparative angiogenesis and inhibits endothelial apoptosis in cutaneous wounds of Type 1 diabetic mice Diabetologia 47 6 1047 1054 10.1007/s00125-004-1414-7
    • (2004) Diabetologia , vol.47 , pp. 1047-1054
    • Graiani, G.1    Emanueli, C.2    Desortes, E.3
  • 8
    • 0034612261 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3
    • 22
    • FM Ho SH Liu CS Liau PJ Huang SY Lin-Shiau 2000 High glucose-induced apoptosis in human endothelial cells is mediated by sequential activations of c-Jun NH(2)-terminal kinase and caspase-3 Circulation 101 22 2618 2624
    • (2000) Circulation , vol.101 , pp. 2618-2624
    • Ho, F.M.1    Liu, S.H.2    Liau, C.S.3    Huang, P.J.4    Lin-Shiau, S.Y.5
  • 9
    • 14644425394 scopus 로고    scopus 로고
    • High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway
    • 3. 10.1161/01.ATV.0000155462.24263.e4
    • ML Sheu FM Ho RS Yang 2005 High glucose induces human endothelial cell apoptosis through a phosphoinositide 3-kinase-regulated cyclooxygenase-2 pathway Arterioscler Thromb Vasc Biol 25 3 539 545 10.1161/01.ATV.0000155462.24263.e4
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 539-545
    • Sheu, M.L.1    Ho, F.M.2    Yang, R.S.3
  • 10
    • 0034904776 scopus 로고    scopus 로고
    • Growth factors can influence cell growth and survival through effects on glucose metabolism
    • 17. 10.1128/MCB.21.17.5899-5912.2001
    • MG Vander Heiden DR Plas JC Rathmell CJ Fox MH Harris CB Thompson 2001 Growth factors can influence cell growth and survival through effects on glucose metabolism Mol Cell Biol 21 17 5899 5912 10.1128/MCB.21.17.5899-5912.2001
    • (2001) Mol Cell Biol , vol.21 , pp. 5899-5912
    • Vander Heiden, M.G.1    Plas, D.R.2    Rathmell, J.C.3    Fox, C.J.4    Harris, M.H.5    Thompson, C.B.6
  • 11
    • 0030771213 scopus 로고    scopus 로고
    • Apoptotic cell death and caspase 3 (CPP32) activation induced by calcium ionophore at low concentrations and their prevention by nerve growth factor in PC12 cells
    • 10.1111/j.1432-1033.1997.00008.x
    • T Takadera T Ohyashiki 1997 Apoptotic cell death and caspase 3 (CPP32) activation induced by calcium ionophore at low concentrations and their prevention by nerve growth factor in PC12 cells Eur J Biochem 249 8 12 10.1111/j.1432-1033.1997.00008.x
    • (1997) Eur J Biochem , vol.249 , pp. 8-12
    • Takadera, T.1    Ohyashiki, T.2
  • 12
    • 33744784302 scopus 로고    scopus 로고
    • 2+ on the DADS-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18)
    • 3. 10.1007/s11064-005-9035-1
    • 2+ on the DADS-induced apoptosis in mouse-rat hybrid retina ganglion cells (N18) Neurochem Res 31 3 383 393 10.1007/s11064-005-9035-1
    • (2006) Neurochem Res , vol.31 , pp. 383-393
    • Lin, H.L.1    Yang, J.S.2    Yang, J.H.3
  • 13
    • 0035865563 scopus 로고    scopus 로고
    • Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes
    • 10.1006/taap.2000.9092
    • HM Shen SY Dong CN Ong 2001 Critical role of calcium overloading in cadmium-induced apoptosis in mouse thymocytes Toxicol Appl Pharmacol 171 12 19 10.1006/taap.2000.9092
    • (2001) Toxicol Appl Pharmacol , vol.171 , pp. 12-19
    • Shen, H.M.1    Dong, S.Y.2    Ong, C.N.3
  • 14
    • 0031977191 scopus 로고    scopus 로고
    • The role of calcium in apoptosis
    • 10.1016/S0143-4160(98)90116-6
    • P Nicotera S Orrenius 1998 The role of calcium in apoptosis Cell Calcium 23 173 180 10.1016/S0143-4160(98)90116-6
    • (1998) Cell Calcium , vol.23 , pp. 173-180
    • Nicotera, P.1    Orrenius, S.2
  • 15
    • 0033558798 scopus 로고    scopus 로고
    • VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
    • 2. 10.1006/excr.1998.4359
    • K Gupta S Kshirsagar W Li 1999 VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling Exp Cell Res 247 2 495 504 10.1006/excr.1998.4359
    • (1999) Exp Cell Res , vol.247 , pp. 495-504
    • Gupta, K.1    Kshirsagar, S.2    Li, W.3
  • 16
    • 30144441076 scopus 로고    scopus 로고
    • Vascular endothelial growth factor signalling in endothelial cell survival: A role for NF-κB
    • 10.1016/j.bbrc.2005.12.095
    • J Grosjean S Kiriakidis K Reilly M Feldmann E Paleolog 2006 Vascular endothelial growth factor signalling in endothelial cell survival: a role for NF-κB Biochem Biophys Res Commun 340 984 994 10.1016/j.bbrc.2005.12.095
    • (2006) Biochem Biophys Res Commun , vol.340 , pp. 984-994
    • Grosjean, J.1    Kiriakidis, S.2    Reilly, K.3    Feldmann, M.4    Paleolog, E.5
  • 17
    • 0036147227 scopus 로고    scopus 로고
    • VEGF protects bovine aortic endothelial cells from TNF-alpha- and H2O2-induced apoptosis via co-modulatory effects on p38-and p42/p44-CCDPK signaling
    • 1
    • WL Liu X Guo QQ Chen ZG Guo 2002 VEGF protects bovine aortic endothelial cells from TNF-alpha- and H2O2-induced apoptosis via co-modulatory effects on p38-and p42/p44-CCDPK signaling Acta Pharmacol Sin 23 1 45 49
    • (2002) Acta Pharmacol Sin , vol.23 , pp. 45-49
    • Liu, W.L.1    Guo, X.2    Chen, Q.Q.3    Guo, Z.G.4
  • 18
    • 0034650288 scopus 로고    scopus 로고
    • Protection by vascular endothelial growth factor against sinusoidal endothelial cell damage and apoptosis induced by cold preservation
    • 10.1097/00007890-200001150-00024
    • T Moriga S Arii Y Takeda 2000 Protection by vascular endothelial growth factor against sinusoidal endothelial cell damage and apoptosis induced by cold preservation Transplantation 69 141 147 10.1097/00007890-200001150-00024
    • (2000) Transplantation , vol.69 , pp. 141-147
    • Moriga, T.1    Arii, S.2    Takeda, Y.3
  • 19
    • 0015822275 scopus 로고
    • Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria
    • 10.1172/JCI107470
    • EA Jaffe RL Nachman CG Becker CR Minick 1973 Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria J Clin Invest 52 2745 2756 10.1172/JCI107470
    • (1973) J Clin Invest , vol.52 , pp. 2745-2756
    • Jaffe, E.A.1    Nachman, R.L.2    Becker, C.G.3    Minick, C.R.4
  • 20
    • 0038353186 scopus 로고    scopus 로고
    • Kallikrein-binding protein inhibits retinal neovascularization and decreases vascular leakage
    • G Gao C Shao SX Zhang A Dudley J Fant JX Ma 2003 Kallikrein-binding protein inhibits retinal neovascularization and decreases vascular leakage Diabetologia 46 689 698
    • (2003) Diabetologia , vol.46 , pp. 689-698
    • Gao, G.1    Shao, C.2    Zhang, S.X.3    Dudley, A.4    Fant, J.5    Ma, J.X.6
  • 21
    • 0022572994 scopus 로고
    • High glucose induces DNA damage in cultured human endothelial cells
    • 10.1172/JCI112295
    • M Lorenzi DF Montisano S Toledo 1986 High glucose induces DNA damage in cultured human endothelial cells J Clin Invest 77 322 325 10.1172/JCI112295
    • (1986) J Clin Invest , vol.77 , pp. 322-325
    • Lorenzi, M.1    Montisano, D.F.2    Toledo, S.3
  • 22
    • 0025832494 scopus 로고
    • Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C
    • 10.1172/JCI115179
    • B Tesfamariam ML Brown RA Cohen 1991 Elevated glucose impairs endothelium-dependent relaxation by activating protein kinase C J Clin Invest 87 1643 1648 10.1172/JCI115179
    • (1991) J Clin Invest , vol.87 , pp. 1643-1648
    • Tesfamariam, B.1    Brown, M.L.2    Cohen, R.A.3
  • 23
    • 0026625948 scopus 로고
    • Hypertension, the endothelial cell, and the vascular complications of diabetes mellitus
    • WA Hsueh PW Anderson 1992 Hypertension, the endothelial cell, and the vascular complications of diabetes mellitus Hypertension 20 253 263
    • (1992) Hypertension , vol.20 , pp. 253-263
    • Hsueh, W.A.1    Anderson, P.W.2
  • 24
    • 0030863502 scopus 로고    scopus 로고
    • Glucose-induced protein kinase C activation regulates vascular permeability factor mRNA expression and peptide production by human vascular smooth muscle cells in vitro
    • 9. 10.2337/diabetes.46.9.1497
    • B Williams B Gallacher H Patel C Orme 1997 Glucose-induced protein kinase C activation regulates vascular permeability factor mRNA expression and peptide production by human vascular smooth muscle cells in vitro Diabetes 46 9 1497 1503 10.2337/diabetes.46.9.1497
    • (1997) Diabetes , vol.46 , pp. 1497-1503
    • Williams, B.1    Gallacher, B.2    Patel, H.3    Orme, C.4
  • 25
    • 14044265526 scopus 로고    scopus 로고
    • Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration
    • 10.1242/jcs.01612
    • AB el-Remessy M Bartoli DH Platt D Fulton RB Caldwell 2005 Oxidative stress inactivates VEGF survival signaling in retinal endothelial cells via PI 3-kinase tyrosine nitration J Cell Sci 118 243 252 10.1242/jcs.01612
    • (2005) J Cell Sci , vol.118 , pp. 243-252
    • El-Remessy, A.B.1    Bartoli, M.2    Platt, D.H.3    Fulton, D.4    Caldwell, R.B.5
  • 26
    • 0034046347 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in response to high glucose in rat mesangial cells
    • 3. 10.1677/joe.0.1650617
    • NH Kim HH Jung DR Cha DS Choi 2000 Expression of vascular endothelial growth factor in response to high glucose in rat mesangial cells J Endocrinol 165 3 617 624 10.1677/joe.0.1650617
    • (2000) J Endocrinol , vol.165 , pp. 617-624
    • Kim, N.H.1    Jung, H.H.2    Cha, D.R.3    Choi, D.S.4
  • 27
    • 0032823055 scopus 로고    scopus 로고
    • Regulation of transforming growth factor-beta, basic fibroblast growth factor, and vascular endothelial cell growth factor mRNA in peripheral blood leukocytes in patients with diabetic retinopathy
    • 10.1016/S0026-0495(99)90134-8
    • RM Knott MM Pascal C Ferguson 1999 Regulation of transforming growth factor-beta, basic fibroblast growth factor, and vascular endothelial cell growth factor mRNA in peripheral blood leukocytes in patients with diabetic retinopathy Metabolism 48 1172 1178 10.1016/S0026-0495(99)90134-8
    • (1999) Metabolism , vol.48 , pp. 1172-1178
    • Knott, R.M.1    Pascal, M.M.2    Ferguson, C.3
  • 28
    • 2942570070 scopus 로고    scopus 로고
    • Vascular factors altered in glucose-treated mesangial cells and diabetic glomeruli. Changes in vascular factors impair endothelial cell growth and matrix
    • 5. 10.1038/labinvest.3700082
    • AK Singh KP Gudehithlu AA Pegoraro 2004 Vascular factors altered in glucose-treated mesangial cells and diabetic glomeruli. Changes in vascular factors impair endothelial cell growth and matrix Lab Invest 84 5 597 606 10.1038/labinvest.3700082
    • (2004) Lab Invest , vol.84 , pp. 597-606
    • Singh, A.K.1    Gudehithlu, K.P.2    Pegoraro, A.A.3
  • 29
    • 0035067375 scopus 로고    scopus 로고
    • Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation
    • E Pinter J Haigh A Nagy J Madri 2001 Hyperglycemia-induced vasculopathy in the murine conceptus is mediated via reductions of VEGF-A expression and VEGF receptor activation Am J Pathol 158 1199 1206
    • (2001) Am J Pathol , vol.158 , pp. 1199-1206
    • Pinter, E.1    Haigh, J.2    Nagy, A.3    Madri, J.4
  • 30
    • 0032541029 scopus 로고    scopus 로고
    • P42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts
    • 29. 10.1074/jbc.273.29.18165
    • J Milanini F Viñals J Pouysségur G Pagès 1998 p42/p44 MAP kinase module plays a key role in the transcriptional regulation of the vascular endothelial growth factor gene in fibroblasts J Biol Chem 273 29 18165 18172 10.1074/jbc.273.29.18165
    • (1998) J Biol Chem , vol.273 , pp. 18165-18172
    • Milanini, J.1    Viñals, F.2    Pouysségur, J.3    Pagès, G.4
  • 31
    • 0034282553 scopus 로고    scopus 로고
    • The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1 alpha
    • 17
    • A Sodhi S Montaner V Patel 2000 The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1 alpha Cancer Res 60 17 4873 4880
    • (2000) Cancer Res , vol.60 , pp. 4873-4880
    • Sodhi, A.1    Montaner, S.2    Patel, V.3
  • 32
    • 42349108136 scopus 로고    scopus 로고
    • Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor
    • 2. 10.1093/cvr/cvm085
    • H Xu P Czerwinski M Hortmann 2008 Protein kinase C alpha promotes angiogenic activity of human endothelial cells via induction of vascular endothelial growth factor Cardiovasc Res 78 2 349 355 10.1093/cvr/cvm085
    • (2008) Cardiovasc Res , vol.78 , pp. 349-355
    • Xu, H.1    Czerwinski, P.2    Hortmann, M.3
  • 33
    • 0033118228 scopus 로고    scopus 로고
    • VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells
    • 13. 10.1038/sj.onc.1202527
    • T Takahashi H Ueno M Shibuya 1999 VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells Oncogene 18 13 2221 2230 10.1038/sj.onc.1202527
    • (1999) Oncogene , vol.18 , pp. 2221-2230
    • Takahashi, T.1    Ueno, H.2    Shibuya, M.3
  • 34
    • 0037088694 scopus 로고    scopus 로고
    • Down-regulation of vascular endothelial growth factor and up-regulation of pigment epithelium-derived factor: A possible mechanism for the anti-angiogenic activity of plasminogen kringle 5
    • 11. 10.1074/jbc.M108004200
    • G Gao Y Li S Gee A Dudley J Fant C Crosson 2002 Down-regulation of vascular endothelial growth factor and up-regulation of pigment epithelium-derived factor: a possible mechanism for the anti-angiogenic activity of plasminogen kringle 5 J Biol Chem 277 11 9492 9497 10.1074/jbc.M108004200
    • (2002) J Biol Chem , vol.277 , pp. 9492-9497
    • Gao, G.1    Li, Y.2    Gee, S.3    Dudley, A.4    Fant, J.5    Crosson, C.6
  • 35
    • 0036325725 scopus 로고    scopus 로고
    • Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane
    • 8. 10.2337/diabetes.51.8.2604
    • H Nakagami R Morishita K Yamamoto 2002 Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane Diabetes 51 8 2604 2611 10.2337/diabetes.51.8.2604
    • (2002) Diabetes , vol.51 , pp. 2604-2611
    • Nakagami, H.1    Morishita, R.2    Yamamoto, K.3
  • 36
    • 6344235539 scopus 로고    scopus 로고
    • Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax
    • 42. 10.1074/jbc.M406412200
    • Z Zhang SM Lapolla MG Annis 2004 Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax J Biol Chem 279 42 43920 43928 10.1074/jbc.M406412200
    • (2004) J Biol Chem , vol.279 , pp. 43920-43928
    • Zhang, Z.1    Lapolla, S.M.2    Annis, M.G.3
  • 37
    • 33744953583 scopus 로고    scopus 로고
    • Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2
    • 21. 10.1074/jbc.M602374200
    • C Tan PJ Dlugosz J Peng 2006 Auto-activation of the apoptosis protein Bax increases mitochondrial membrane permeability and is inhibited by Bcl-2 J Biol Chem 281 21 14764 14775 10.1074/jbc.M602374200
    • (2006) J Biol Chem , vol.281 , pp. 14764-14775
    • Tan, C.1    Dlugosz, P.J.2    Peng, J.3
  • 38
    • 33749518527 scopus 로고    scopus 로고
    • Interaction of vascular endothelial growth factor 165 with neuropilin-1 protects rheumatoid synoviocytes from apoptotic death by regulating Bcl-2 expression and Bax translocation
    • 8
    • WU Kim SS Kang SA Yoo 2006 Interaction of vascular endothelial growth factor 165 with neuropilin-1 protects rheumatoid synoviocytes from apoptotic death by regulating Bcl-2 expression and Bax translocation J Immunol 177 8 5727 5735
    • (2006) J Immunol , vol.177 , pp. 5727-5735
    • Kim, W.U.1    Kang, S.S.2    Yoo, S.A.3
  • 39
    • 0036604133 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor
    • 11
    • N Munshi AZ Fernandis RP Cherla IW Park RK Ganju 2002 Lipopolysaccharide-induced apoptosis of endothelial cells and its inhibition by vascular endothelial growth factor J Immunol 168 11 5860 5866
    • (2002) J Immunol , vol.168 , pp. 5860-5866
    • Munshi, N.1    Fernandis, A.Z.2    Cherla, R.P.3    Park, I.W.4    Ganju, R.K.5
  • 40
    • 0030780106 scopus 로고    scopus 로고
    • Movement of Bax from the cytosol to mitochondria during apoptosis
    • 5. 10.1083/jcb.139.5.1281
    • KG Wolter YT Hsu CL Smith A Nechushtan XG Xi RJ Youle 1997 Movement of Bax from the cytosol to mitochondria during apoptosis J Cell Biol 139 5 1281 1292 10.1083/jcb.139.5.1281
    • (1997) J Cell Biol , vol.139 , pp. 1281-1292
    • Wolter, K.G.1    Hsu, Y.T.2    Smith, C.L.3    Nechushtan, A.4    G X. Xi5    Youle, R.J.6
  • 41
    • 0032487582 scopus 로고    scopus 로고
    • Regulated targeting of BAX to mitochondria
    • 1. 10.1083/jcb.143.1.207
    • IS Goping A Gross JN Lavoie 1998 Regulated targeting of BAX to mitochondria J Cell Biol 143 1 207 215 10.1083/jcb.143.1.207
    • (1998) J Cell Biol , vol.143 , pp. 207-215
    • Goping, I.S.1    Gross, A.2    Lavoie, J.N.3
  • 42
    • 0030963602 scopus 로고    scopus 로고
    • Cytosol-to-membrane redistribution of bax and bcl-xL during apoptosis
    • 10.1073/pnas.94.8.3668
    • YT Hsu KG Wolter RJ Youle 1997 Cytosol-to-membrane redistribution of bax and bcl-xL during apoptosis Proc Natl Acad Sci USA 94 3668 3672 10.1073/pnas.94.8.3668
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3668-3672
    • Hsu, Y.T.1    Wolter, K.G.2    Youle, R.J.3
  • 43
    • 0032528118 scopus 로고    scopus 로고
    • Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis
    • 10.1093/emboj/17.14.3878
    • A Gross J Jennifer MC Wei SJ Korsmeyer 1998 Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis EMBO J 17 3878 3885 10.1093/emboj/17.14.3878
    • (1998) EMBO J , vol.17 , pp. 3878-3885
    • Gross, A.1    Jennifer, J.2    Wei, M.C.3    Korsmeyer, S.J.4
  • 44
    • 27844593740 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3 K/Akt/eNOS pathway
    • 3. 10.1016/j.cellsig.2005.05.009
    • FM Ho WW Lin BC Chen 2006 High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3 K/Akt/eNOS pathway Cell Signal 18 3 391 399 10.1016/j.cellsig.2005.05.009
    • (2006) Cell Signal , vol.18 , pp. 391-399
    • Ho, F.M.1    Lin, W.W.2    Chen, B.C.3
  • 45
    • 0036491629 scopus 로고    scopus 로고
    • 2+ homeostasis and store-operated channels in prostate cancer cells
    • 10.1016/S1535-6108(02)00034-X
    • 2+ homeostasis and store-operated channels in prostate cancer cells Cancer Cell 1 169 179 10.1016/S1535-6108(02)00034-X
    • (2002) Cancer Cell , vol.1 , pp. 169-179
    • Vanden Abeele, F.1    Skryma, R.2    Shuba, Y.3
  • 46
    • 14644395593 scopus 로고    scopus 로고
    • Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis
    • 3. 10.1161/01.ATV.0000154359.60886.33
    • C Vindis M Elbaz I Escargueil-Blanc 2005 Two distinct calcium-dependent mitochondrial pathways are involved in oxidized LDL-induced apoptosis Arterioscler Thromb Vasc Biol 5 3 639 645 10.1161/01.ATV.0000154359.60886.33
    • (2005) Arterioscler Thromb Vasc Biol , vol.5 , pp. 639-645
    • Vindis, C.1    Elbaz, M.2    Escargueil-Blanc, I.3
  • 47
    • 29444461333 scopus 로고    scopus 로고
    • High glucose-induced apoptosis through store-operated calcium entry and calcineurin in human umbilical vein endothelial cells
    • S Tamareille O Mignen T Capiod C Rucker-Martin D Feuvray 2006 High glucose-induced apoptosis through store-operated calcium entry and calcineurin in human umbilical vein endothelial cells Cell Calcium 39 47 55
    • (2006) Cell Calcium , vol.39 , pp. 47-55
    • Tamareille, S.1    Mignen, O.2    Capiod, T.3    Rucker-Martin, C.4    Feuvray, D.5
  • 48
    • 0026089929 scopus 로고
    • 2+ and von Willebrand factor release in human endothelial cells
    • 1
    • 2+ and von Willebrand factor release in human endothelial cells Am J Pathol 138 1 213 221
    • (1991) Am J Pathol , vol.138 , pp. 213-221
    • Brock, T.A.1    Dvorak, H.F.2    Senger, D.R.3
  • 49
    • 4644318740 scopus 로고    scopus 로고
    • Functional characterization of HUVEC-CS: Ca2+ signaling, ERK 1/2 activation, mitogenesis and vasodilator production
    • 3. 10.1677/joe.0.1820485
    • SM Gifford MA Grummer SA Pierre JL Austin J Zheng IM Bird 2004 Functional characterization of HUVEC-CS: Ca2+ signaling, ERK 1/2 activation, mitogenesis and vasodilator production J Endocrinol 182 3 485 499 10.1677/joe.0.1820485
    • (2004) J Endocrinol , vol.182 , pp. 485-499
    • Gifford, S.M.1    Grummer, M.A.2    Pierre, S.A.3    Austin, J.L.4    Zheng, J.5    Bird, I.M.6
  • 50
    • 0036831825 scopus 로고    scopus 로고
    • Essential role of calcium in vascular endothelial growth factor A-induced signaling: Mechanism of the antiangiogenic effect of carboxyamidotriazole
    • 13
    • M Faehling J Kroll KJ Fohr 2002 Essential role of calcium in vascular endothelial growth factor A-induced signaling: mechanism of the antiangiogenic effect of carboxyamidotriazole FASEB J 16 13 1805 1807
    • (2002) FASEB J , vol.16 , pp. 1805-1807
    • Faehling, M.1    Kroll, J.2    Fohr, K.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.