Vascular dysfunction in experimental diabetes is improved by pentaerithrityl tetranitrate but not isosorbide-5-mononitrate therapy

Diabetes

Volumn 60, Issue 10, 2011, Pages 2608-2616

  Schuhmacher, Swenja ^a   Oelze, Matthias ^a   Bollmann, Franziska ^a   Kleinert, Hartmut ^a   Otto, Christian ^a   Heeren, Tjebo ^a   Steven, Sebastian ^a   Hausding, Michael ^a   Knorr, Maike ^a   Pautz, Andrea ^a   Reifenberg, Kurt ^a   Schulz, Eberhard ^a   Gori, Tommaso ^a   Wenzel, Philip ^a   Münzel, Thomas ^a   Daiber, Andreas ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GUANOSINE TRIPHOSPHATE CYCLOHYDROLASE I; HEME OXYGENASE 1; ISOSORBIDE 5 NITRATE; PENTAERYTHRITYL TETRANITRATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; RNA; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENDOTHELIAL DYSFUNCTION; GLUCOSE BLOOD LEVEL; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STREPTOZOCIN DIABETES; UPREGULATION; VASCULAR DISEASE; WEIGHT GAIN; WESTERN BLOTTING;

ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; ENDOTHELIUM, VASCULAR; GENE SILENCING; GTP CYCLOHYDROLASE; HEME OXYGENASE-1; ISOSORBIDE DINITRATE; MALE; NADPH OXIDASE; OXIDATIVE STRESS; PENTAERYTHRITOL TETRANITRATE; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; VASOCONSTRICTION; VASODILATOR AGENTS; WEIGHT GAIN; XANTHINE OXIDASE;

EID: 80053425581     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-1395     Document Type: Article

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