Inhibitory effects of fenofibrate on apoptosis and cell proliferation in human endothelial cells in high glucose

Journal of Molecular Medicine

Volumn 86, Issue 2, 2008, Pages 185-195

  Zanetti, Michela ^a   Stocca, Alessia ^a   Dapas, Barbara ^a   Farra, Rossella ^a   Uxa, Laura ^b   Bosutti, Alessandra ^a   Barazzoni, Rocco ^a   Bossi, Fleur ^b   Giansante, Carlo ^a   Tedesco, Francesco ^b   Cattin, Luigi ^a   Guarnieri, Gianfranco ^a   Grassi, Gabriele ^a,c  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Apoptosis; Cell proliferation; Diabetes mellitus; Endothelium; Macrovascular disease

Indexed keywords

CYCLIN D1; CYCLOOXYGENASE 2; FENOFIBRATE; GLUCOSE; GLYCOPROTEIN E1; PROTEASOME; RETINOBLASTOMA PROTEIN; TRANSCRIPTION FACTOR E2F1;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; UMBILICAL VEIN;

ANTILIPEMIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CYCLIN A; CYCLIN E; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; E2F1 TRANSCRIPTION FACTOR; ENDOTHELIAL CELLS; GLUCOSE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ONCOGENE PROTEINS; PHOSPHORYLATION; PPAR ALPHA; PROCETOFEN; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-BCL-2; RETINOBLASTOMA PROTEIN; SUPEROXIDES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 38649101592     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-007-0257-3     Document Type: Article

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