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Volumn 10, Issue 4, 1999, Pages 241-256

Endothelial function and atherosclerosis

Author keywords

Atherosclerosis; Endothelium derived relaxing factor; Nitric oxide; Oxidative stress

Indexed keywords

2 OXO 4 THIAZOLIDINECARBOXYLIC ACID; ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; ARGININE; ASCORBIC ACID; BETA CAROTENE; COLESTYRAMINE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ESTROGEN; FOLIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEDROXYPROGESTERONE; MEVINOLIN; PROBUCOL; TETRAHYDROBIOPTERIN;

EID: 0032773364     PISSN: 09546928     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019501-199906000-00006     Document Type: Review
Times cited : (78)

References (223)
  • 1
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
    • Furchgott RF, Zawadski JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 1980; 288:373-376. A seminal animal study that demonstrated that exposure of isolated rabbit aorta to acetylcholine caused vasodilatation if the endothelium was intact, but vasoconstriction if the endothelium was removed. This landmark study established the field of EDRF/NO.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadski, J.V.2
  • 2
    • 0023505509 scopus 로고
    • Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
    • Ignarro LJ, Buga GM, Wood KS, Byrns RE, Chaudhuri G. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide. Proc Natl Acad Sci USA 1987; 84:9265-9269.
    • (1987) Proc Natl Acad Sci USA , vol.84 , pp. 9265-9269
    • Ignarro, L.J.1    Buga, G.M.2    Wood, K.S.3    Byrns, R.E.4    Chaudhuri, G.5
  • 3
    • 0027104253 scopus 로고
    • Biochemistry of nitric oxide and its redox-associated forms
    • Stamler JS, Singel DJ, Loscalzo J. Biochemistry of nitric oxide and its redox-associated forms. Science 1992; 258:1898-1902.
    • (1992) Science , vol.258 , pp. 1898-1902
    • Stamler, J.S.1    Singel, D.J.2    Loscalzo, J.3
  • 4
    • 0023912670 scopus 로고
    • Vascular endothelial cells synthesize nitric oxide from L-arginine
    • Palmer RMJ, Ashton DS, Moncada S. Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 1988; 333:664-666.
    • (1988) Nature , vol.333 , pp. 664-666
    • Palmer, R.M.J.1    Ashton, D.S.2    Moncada, S.3
  • 5
    • 0024208276 scopus 로고
    • Macrophage oxidation of L-arginine to nitrite and nitrate: Nitric oxide is an intermediate
    • Marletta MA, Yoon PS, Ihengar R, Leaf CK, Wishnok JS. Macrophage oxidation of L-arginine to nitrite and nitrate: nitric oxide is an intermediate. Biochemistry 1988; 27:8706-8711.
    • (1988) Biochemistry , vol.27 , pp. 8706-8711
    • Marletta, M.A.1    Yoon, P.S.2    Ihengar, R.3    Leaf, C.K.4    Wishnok, J.S.5
  • 6
    • 0021894599 scopus 로고
    • The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation
    • Ignarro LJ, Kadowitz PJ. The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation. Ann Rev Pharmacol Toxicol 1985; 25:171-191.
    • (1985) Ann Rev Pharmacol Toxicol , vol.25 , pp. 171-191
    • Ignarro, L.J.1    Kadowitz, P.J.2
  • 7
    • 0021064044 scopus 로고
    • Role of endothelium in responses of vascular smooth muscle
    • Furchgott RF. Role of endothelium in responses of vascular smooth muscle. Circ Res 1983; 53:557-573.
    • (1983) Circ Res , vol.53 , pp. 557-573
    • Furchgott, R.F.1
  • 8
    • 0022516979 scopus 로고
    • Flow-induced release of endothelium-derived relaxing factor
    • Rubanyi GM, Romero JC, Vanhoutte PM. Flow-induced release of endothelium-derived relaxing factor. Am J Physiol 1986; 250:H1145-H1149.
    • (1986) Am J Physiol , vol.250
    • Rubanyi, G.M.1    Romero, J.C.2    Vanhoutte, P.M.3
  • 9
    • 0025724919 scopus 로고
    • Flow activates an endothelial potassium channel to release endogenous nitrovasodilator
    • Cooke JP, Rossitch E Jr, Andon NA, Loscalzo J, Dzau VJ. Flow activates an endothelial potassium channel to release endogenous nitrovasodilator. J Clin Invest 1991; 88:1663-1671.
    • (1991) J Clin Invest , vol.88 , pp. 1663-1671
    • Cooke, J.P.1    Rossitch E., Jr.2    Andon, N.A.3    Loscalzo, J.4    Dzau, V.J.5
  • 11
    • 0024238725 scopus 로고
    • Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels
    • Chen G, Suzuki H, Weston AH. Acetylcholine releases endothelium-derived hyperpolarizing factor and EDRF from rat blood vessels. Br J Pharmacol 1988; 95:1165-1174.
    • (1988) Br J Pharmacol , vol.95 , pp. 1165-1174
    • Chen, G.1    Suzuki, H.2    Weston, A.H.3
  • 12
    • 0018722331 scopus 로고
    • Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides
    • Pearson JD, Gordon JL. Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides. Nature 1979; 281:384-386.
    • (1979) Nature , vol.281 , pp. 384-386
    • Pearson, J.D.1    Gordon, J.L.2
  • 13
    • 0027986532 scopus 로고
    • Thrombosis and inflammation as multicellular processes: Significance of cell-cell interactions
    • Marcus AJ. Thrombosis and inflammation as multicellular processes: significance of cell-cell interactions. Seminars Hematol 1994; 31:261-269.
    • (1994) Seminars Hematol , vol.31 , pp. 261-269
    • Marcus, A.J.1
  • 14
    • 0022052915 scopus 로고
    • Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase
    • Miller VM, Vanhouette PM. Endothelium-dependent contractions to arachidonic acid are mediated by products of cyclooxygenase. Am J Physiol 1985; 248:H432-H437.
    • (1985) Am J Physiol , vol.248
    • Miller, V.M.1    Vanhouette, P.M.2
  • 15
    • 0023859136 scopus 로고
    • A novel potent vasoconstrictor peptide produced by vascular endothelial cells
    • Yanagisawa M, Kurihara H, Klimura S, Tomobe Y, Kobayashi M, Mitsui Y, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332:411-415. In this article, the isolation of endothelin-1, a 21-amino-acid peptide, is described, and it is shown to be a potent vasoconstrictor.
    • (1988) Nature , vol.332 , pp. 411-415
    • Yanagisawa, M.1    Kurihara, H.2    Klimura, S.3    Tomobe, Y.4    Kobayashi, M.5    Mitsui, Y.6
  • 16
    • 0029116310 scopus 로고
    • Endothelins
    • Levin ER. Endothelins. N Engl J Med 1995; 333:356-363.
    • (1995) N Engl J Med , vol.333 , pp. 356-363
    • Levin, E.R.1
  • 17
    • 0025239666 scopus 로고
    • Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins
    • Luscher TF, Yang Z, Tschudi M, von Segesser L, Stulz P, Boulanger C, et al. Interaction between endothelin-1 and endothelium-derived relaxing factor in human arteries and veins. Circ Res 1990; 66:1088-1094.
    • (1990) Circ Res , vol.66 , pp. 1088-1094
    • Luscher, T.F.1    Yang, Z.2    Tschudi, M.3    Von Segesser, L.4    Stulz, P.5    Boulanger, C.6
  • 18
    • 0021676129 scopus 로고
    • Vascular wall renin angiotensin pathway in control of the circulation
    • Dzau VJ. Vascular wall renin angiotensin pathway in control of the circulation. Am J Med 1984; 77:31-36. This review describes the features of the vascular wall renin-angiotensin system and its role in cardiovascular homeostasis. The author postulates that abnormalities in the control of this system may result in local vasospasm or systemic hypertension.
    • (1984) Am J Med , vol.77 , pp. 31-36
    • Dzau, V.J.1
  • 19
    • 0023267525 scopus 로고
    • Endothelial renin-angiotensin pathway: Evidence for intracellular synthesis and secretion of angiotensins
    • Kifor I, Dzau VJ. Endothelial renin-angiotensin pathway: evidence for intracellular synthesis and secretion of angiotensins. Circ Res 1987; 60:422-428.
    • (1987) Circ Res , vol.60 , pp. 422-428
    • Kifor, I.1    Dzau, V.J.2
  • 20
    • 0017577412 scopus 로고
    • Metabolism of vasoactive peptides by human endothelial cells in culture. Angiotensin I converting enzyme (kininase III) and angiotensinase
    • Johnson AR, Erdos EG. Metabolism of vasoactive peptides by human endothelial cells in culture. Angiotensin I converting enzyme (kininase III) and angiotensinase. J Clin Invest 1977; 59:684-695.
    • (1977) J Clin Invest , vol.59 , pp. 684-695
    • Johnson, A.R.1    Erdos, E.G.2
  • 21
    • 0017785124 scopus 로고
    • Accentuated vascular and endocrine response to SQ20,881 in hypertension
    • Williams GH, Hollenberg NK. Accentuated vascular and endocrine response to SQ20,881 in hypertension. N Engl J Med 1977; 287:194-201.
    • (1977) N Engl J Med , vol.287 , pp. 194-201
    • Williams, G.H.1    Hollenberg, N.K.2
  • 22
    • 0022599662 scopus 로고
    • Endothelium-dependent inhibition of platelet aggregation
    • Ayuma H, Ishikawa M, Sakiyaki S. Endothelium-dependent inhibition of platelet aggregation. Br J Pharmacol 1986; 80:411-415.
    • (1986) Br J Pharmacol , vol.80 , pp. 411-415
    • Ayuma, H.1    Ishikawa, M.2    Sakiyaki, S.3
  • 23
    • 0023200487 scopus 로고
    • Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium
    • Radomski MW, Palmer RM, Moncada S. Endogenous nitric oxide inhibits human platelet adhesion to vascular endothelium. Lancet 1987;ii:1057-1058. The adhesion of human platelets to monolayers of bovine endothelial cells in culture was studied to determine the role of endothelium-derived nitric oxide in the regulation of adhesion of platelets. The results show that release of nitric oxide contributes to the nonadhesive properties of vascular endothelium.
    • (1987) Lancet , vol.2 , pp. 1057-1058
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 24
    • 0023446425 scopus 로고
    • The antiaggregating properties of vascular endothelium: Interactions between prostacyclin and nitric oxide
    • 2 as inhibitors of aggregation of platelets were examined.
    • (1987) Br J Pharmacol , vol.92 , pp. 639-646
    • Radomski, M.W.1    Palmer, R.M.2    Moncada, S.3
  • 25
    • 0017711349 scopus 로고    scopus 로고
    • Prostacyclin increases cyclic AMP levels and adenylate cyclase activity in platelets
    • Best LC, Martin TJ, Russell RG, Preston FE. Prostacyclin increases cyclic AMP levels and adenylate cyclase activity in platelets. Nature 1997; 267:850-852.
    • (1997) Nature , vol.267 , pp. 850-852
    • Best, L.C.1    Martin, T.J.2    Russell, R.G.3    Preston, F.E.4
  • 26
    • 0023878659 scopus 로고
    • Synergistic inhibition of platelet aggregation by endothelium-derived relaxing factor and prostacyclin
    • MacDonald PS, Read MA, Dusting GJ. Synergistic inhibition of platelet aggregation by endothelium-derived relaxing factor and prostacyclin. Thromb Res 1988; 49:181-187.
    • (1988) Thromb Res , vol.49 , pp. 181-187
    • Macdonald, P.S.1    Read, M.A.2    Dusting, G.J.3
  • 28
    • 0022559198 scopus 로고
    • Endothelial cell metabolism of biogenic amines
    • Shepro D, Dunham B. Endothelial cell metabolism of biogenic amines. Annu Rev Physiol 1986; 48:335-345.
    • (1986) Annu Rev Physiol , vol.48 , pp. 335-345
    • Shepro, D.1    Dunham, B.2
  • 30
    • 0022892749 scopus 로고
    • Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparan sulfate proteoglycan
    • Marcum JA, Atha DH, Fritze LMS, Nawroth P, Stern D, Rosenberg RD. Cloned bovine aortic endothelial cells synthesize anticoagulantly active heparan sulfate proteoglycan. J Biol Chem 1986;261:7505-7517.
    • (1986) J Biol Chem , vol.261 , pp. 7505-7517
    • Marcum, J.A.1    Atha, D.H.2    Fritze, L.M.S.3    Nawroth, P.4    Stern, D.5    Rosenberg, R.D.6
  • 31
    • 0021133167 scopus 로고
    • Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium
    • Marcum JA, McKenney, Rosenberg RD. Acceleration of thrombin-antithrombin complex formation in rat hindquarters via heparinlike molecules bound to the endothelium. J Clin Invest 1984; 74:341-350. The authors demonstrate that contact of the hemostatic components with the endothelium enhances the rate of formation of thrombin-antithrombin complex: Heparin-like molecules present on the vascular endothelium are responsible for the antithrombin-accelerating activity.
    • (1984) J Clin Invest , vol.74 , pp. 341-350
    • Marcum, J.A.1    McKenney2    Rosenberg, R.D.3
  • 32
    • 0020063793 scopus 로고
    • Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C
    • Esmon NL, Owen WG, Esmon CT. Isolation of a membrane-bound cofactor for thrombin-catalyzed activation of protein C. J Biol Chem 1982; 257:859-864.
    • (1982) J Biol Chem , vol.257 , pp. 859-864
    • Esmon, N.L.1    Owen, W.G.2    Esmon, C.T.3
  • 33
    • 0020404408 scopus 로고
    • Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation
    • Esmon CT, Esmon NL, Harris KW. Complex formation between thrombin and thrombomodulin inhibits both thrombin-catalyzed fibrin formation and factor V activation. J Biol Chem 1982; 257:7944-7947.
    • (1982) J Biol Chem , vol.257 , pp. 7944-7947
    • Esmon, C.T.1    Esmon, N.L.2    Harris, K.W.3
  • 34
    • 0000650903 scopus 로고
    • Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C
    • Esmon CT, Owen WG. Identification of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. Proc Natl Acad Sci USA 1982; 78:2249-2252.
    • (1982) Proc Natl Acad Sci USA , vol.78 , pp. 2249-2252
    • Esmon, C.T.1    Owen, W.G.2
  • 35
    • 0020072618 scopus 로고
    • Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme
    • Marlar RA, Kleiss AJ, Griffin JH. Mechanism of action of human activated protein C, a thrombin-dependent anticoagulant enzyme. Blood 1982; 59:1067-1072.
    • (1982) Blood , vol.59 , pp. 1067-1072
    • Marlar, R.A.1    Kleiss, A.J.2    Griffin, J.H.3
  • 36
    • 0019791930 scopus 로고
    • Generation of fibrinolytic activity by infusion of activated protein C into dogs
    • Comp PC, Esmon CT. Generation of fibrinolytic activity by infusion of activated protein C into dogs. J Clin Invest 1981; 68:1221-1228.
    • (1981) J Clin Invest , vol.68 , pp. 1221-1228
    • Comp, P.C.1    Esmon, C.T.2
  • 38
    • 0019849380 scopus 로고
    • Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation
    • Walker FJ. Regulation of activated protein C by protein S. The role of phospholipid in factor Va inactivation. J Biol Chem 1981; 256:11128-11131.
    • (1981) J Biol Chem , vol.256 , pp. 11128-11131
    • Walker, F.J.1
  • 39
    • 0022652605 scopus 로고
    • Human endothelial cells synthesize protein S
    • Fair DS, Marlar RA, Levin EG. Human endothelial cells synthesize protein S. Blood 1986; 67:1168-1171.
    • (1986) Blood , vol.67 , pp. 1168-1171
    • Fair, D.S.1    Marlar, R.A.2    Levin, E.G.3
  • 40
    • 0011694667 scopus 로고
    • Synthesis of von Willebrand factor by cultured human endothelial cells
    • Jaffe EA, Hoyer LW, Nachman RL. Synthesis of von Willebrand factor by cultured human endothelial cells. Proc Natl Acad Sci USA 1974; 71:1906-1909.
    • (1974) Proc Natl Acad Sci USA , vol.71 , pp. 1906-1909
    • Jaffe, E.A.1    Hoyer, L.W.2    Nachman, R.L.3
  • 41
    • 85047692049 scopus 로고
    • Role of von Willebrand factor in platelet adhesion to the subendothelium
    • Meyer D, Baumgartner HR. Role of von Willebrand factor in platelet adhesion to the subendothelium. Br J Haematol 1983; 54:1-9.
    • (1983) Br J Haematol , vol.54 , pp. 1-9
    • Meyer, D.1    Baumgartner, H.R.2
  • 42
    • 0021717485 scopus 로고
    • Platelet interaction with rabbit subendothelium in von Willebrand's disease: Altered thrombus formation distinct from defective platelet adhesion
    • Turitto VT, Weiss HJ, Baumgartner HR. Platelet interaction with rabbit subendothelium in von Willebrand's disease: altered thrombus formation distinct from defective platelet adhesion. J Clin Invest 1984; 74:1730-1741.
    • (1984) J Clin Invest , vol.74 , pp. 1730-1741
    • Turitto, V.T.1    Weiss, H.J.2    Baumgartner, H.R.3
  • 43
    • 0343759135 scopus 로고
    • Synthesis of a fibrinolytic activator and inhibitor by endothelial cells
    • Loskutoff DJ, Edgington TS. Synthesis of a fibrinolytic activator and inhibitor by endothelial cells. Proc Natl Acad Sci USA 1977; 74:3903-3907.
    • (1977) Proc Natl Acad Sci USA , vol.74 , pp. 3903-3907
    • Loskutoff, D.J.1    Edgington, T.S.2
  • 44
    • 0020472522 scopus 로고
    • Kinetics of the activation of plasminogen by human tissue plasminogen activator: The role of fibrin
    • Hoylaerts M, Dingeman CR, Lijnen HR, Collen D. Kinetics of the activation of plasminogen by human tissue plasminogen activator: the role of fibrin. J Biol Chem 1982; 257:2912-2919.
    • (1982) J Biol Chem , vol.257 , pp. 2912-2919
    • Hoylaerts, M.1    Dingeman, C.R.2    Lijnen, H.R.3    Collen, D.4
  • 45
    • 0025363927 scopus 로고
    • Identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase
    • Hajjar KA, Hamel NM. Identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase. J Biol Chem 1989; 265:2908-2916.
    • (1989) J Biol Chem , vol.265 , pp. 2908-2916
    • Hajjar, K.A.1    Hamel, N.M.2
  • 46
    • 0021736924 scopus 로고
    • Thrombin stimulates tissue plasminogen activator release from culture human endothelial cells
    • Levin EG, Marzec U, Anderson J, Harker LA. Thrombin stimulates tissue plasminogen activator release from culture human endothelial cells. J Clin Invest 1984; 74:1988-1995.
    • (1984) J Clin Invest , vol.74 , pp. 1988-1995
    • Levin, E.G.1    Marzec, U.2    Anderson, J.3    Harker, L.A.4
  • 47
    • 45949121083 scopus 로고
    • Secretion of tissue-type plasminogen activator and plasminogen activator inhibitor by cultured human endothelial cells: Modulation by thrombin, endotoxin, and histamine
    • Hanss M, Collen D. Secretion of tissue-type plasminogen activator and plasminogen activator inhibitor by cultured human endothelial cells:modulation by thrombin, endotoxin, and histamine. J Lab Clin Med 1987; 109:97-104. Endothelial cells in culture are shown to produce greater amounts of t-PA and PAI-1 in response to thrombin and other stimuli.
    • (1987) J Lab Clin Med , vol.109 , pp. 97-104
    • Hanss, M.1    Collen, D.2
  • 48
    • 0023890531 scopus 로고
    • Stimulation and desensitization of tissue plasminogen activator release from human endothelial cells
    • Levin EG, Santell L. Stimulation and desensitization of tissue plasminogen activator release from human endothelial cells. J Biol Chem 1988; 263:9360-9365.
    • (1988) J Biol Chem , vol.263 , pp. 9360-9365
    • Levin, E.G.1    Santell, L.2
  • 49
    • 0024522606 scopus 로고
    • Fluid flow stimulates tissue plasminogen activator secretion by cultured human endothelial cells
    • Diamond SL, Eskin SG, McIntire LV. Fluid flow stimulates tissue plasminogen activator secretion by cultured human endothelial cells. Science 1989; 243:1483-1485.
    • (1989) Science , vol.243 , pp. 1483-1485
    • Diamond, S.L.1    Eskin, S.G.2    McIntire, L.V.3
  • 50
    • 0022536999 scopus 로고
    • Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin-1
    • Bevilacqua MP, Schleef RR, Gimbrone MA, Loskutoff DJ. Regulation of the fibrinolytic system of cultured human vascular endothelium by interleukin-1. J Clin Invest 1986; 78:587-591.
    • (1986) J Clin Invest , vol.78 , pp. 587-591
    • Bevilacqua, M.P.1    Schleef, R.R.2    Gimbrone, M.A.3    Loskutoff, D.J.4
  • 51
    • 0023899499 scopus 로고
    • Alpha-tocopherol, a potent modulator of endothelial cell function
    • Huang N, Lineberger B, Steiner M. Alpha-tocopherol, a potent modulator of endothelial cell function. Thromb Res 1988; 50:547-557.
    • (1988) Thromb Res , vol.50 , pp. 547-557
    • Huang, N.1    Lineberger, B.2    Steiner, M.3
  • 52
    • 0020646834 scopus 로고
    • Plasminogen activator release during venous stasis and exercise as determined by a new specific assay
    • Wiman B, Mellbring G, Ranby M, Plasminogen activator release during venous stasis and exercise as determined by a new specific assay. Clin Chim Acta 1983; 127:279-288.
    • (1983) Clin Chim Acta , vol.127 , pp. 279-288
    • Wiman, B.1    Mellbring, G.2    Ranby, M.3
  • 53
    • 0020681974 scopus 로고
    • Measurement of human tissue-type plasminogen activator by a two-site immunoradiometric assay
    • Rijken DC, Juhan-Vague I, de Cock F, Collen D. Measurement of human tissue-type plasminogen activator by a two-site immunoradiometric assay. J Lab Clin Med 1983; 101:274-284.
    • (1983) J Lab Clin Med , vol.101 , pp. 274-284
    • Rijken, D.C.1    Juhan-Vague, I.2    De Cock, F.3    Collen, D.4
  • 54
    • 0021687079 scopus 로고
    • Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells
    • van Mourik JA, Lawrence DE, Loskutoff DJ. Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells. J Biol Chem 1984; 259:14914-14921.
    • (1984) J Biol Chem , vol.259 , pp. 14914-14921
    • Van Mourik, J.A.1    Lawrence, D.E.2    Loskutoff, D.J.3
  • 55
    • 0022599303 scopus 로고
    • Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells
    • Gelehrter TD, Sznycer-Laszuk R. Thrombin induction of plasminogen activator-inhibitor in cultured human endothelial cells. J Clin Invest 1986; 77:165-169.
    • (1986) J Clin Invest , vol.77 , pp. 165-169
    • Gelehrter, T.D.1    Sznycer-Laszuk, R.2
  • 56
    • 0021986774 scopus 로고
    • Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation
    • Colucci M, Paramo JA, Collen D. Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation. J Clin Invest 1984; 75:818-824.
    • (1984) J Clin Invest , vol.75 , pp. 818-824
    • Colucci, M.1    Paramo, J.A.2    Collen, D.3
  • 57
    • 0022910521 scopus 로고
    • Mechanism of protein C-dependent clot lysis: Role of plasminogen activator inhibitor
    • Sakata Y, Loskutoff DJ, Gladson CL, Hekman CM, Griffin JH. Mechanism of protein C-dependent clot lysis: role of plasminogen activator inhibitor. Blood 1986; 68:1218-1223.
    • (1986) Blood , vol.68 , pp. 1218-1223
    • Sakata, Y.1    Loskutoff, D.J.2    Gladson, C.L.3    Hekman, C.M.4    Griffin, J.H.5
  • 58
    • 0024553336 scopus 로고
    • Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells
    • Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromocyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest 1989; 83:1774-1777.
    • (1989) J Clin Invest , vol.83 , pp. 1774-1777
    • Garg, U.C.1    Hassid, A.2
  • 59
    • 0027729352 scopus 로고
    • Effects of beraprost sodium, a stable analogue of prostacyclin, on hyperplasia, hypertrophy and glycosaminoglycan synthesis of rat aortic smooth muscle cells
    • Koh E, Morimoto S, Jiang B, Inoue T, Nabata T, Kitano S, et al. Effects of beraprost sodium, a stable analogue of prostacyclin, on hyperplasia, hypertrophy and glycosaminoglycan synthesis of rat aortic smooth muscle cells. Artery 1993; 20:242-252.
    • (1993) Artery , vol.20 , pp. 242-252
    • Koh, E.1    Morimoto, S.2    Jiang, B.3    Inoue, T.4    Nabata, T.5    Kitano, S.6
  • 60
    • 0027441134 scopus 로고
    • Endothelial control of cell migration and proliferation
    • Graf H. Endothelial control of cell migration and proliferation. Eur Heart J 1993; 14:183-186. This article describes the inhibitory effect of prostacyclin on proliferation of smooth muscle cells.
    • (1993) Eur Heart J , vol.14 , pp. 183-186
    • Graf, H.1
  • 61
    • 0019829625 scopus 로고
    • Cultured endothelial cells produce a heparin-like inhibitor of smooth muscle cell growth
    • Castellot JJ Jr, Addonizio ML, Rosenberg R, Karnovsky M. Cultured endothelial cells produce a heparin-like inhibitor of smooth muscle cell growth. J Cell Biol 1981; 90:372-379.
    • (1981) J Cell Biol , vol.90 , pp. 372-379
    • Castellot J.J., Jr.1    Addonizio, M.L.2    Rosenberg, R.3    Karnovsky, M.4
  • 62
    • 0024520374 scopus 로고
    • Vasoactive effects of growth factors [commentary]
    • Berk BD, Alexander RW. Vasoactive effects of growth factors [commentary]. Biochem Pharmacol 1989; 38:219-225.
    • (1989) Biochem Pharmacol , vol.38 , pp. 219-225
    • Berk, B.D.1    Alexander, R.W.2
  • 63
    • 0028300301 scopus 로고
    • The emerging concept of vascular remodeling
    • Gibbons GH, Dzau VJ. The emerging concept of vascular remodeling. N Engl J Med 1994; 330:1431-1438.
    • (1994) N Engl J Med , vol.330 , pp. 1431-1438
    • Gibbons, G.H.1    Dzau, V.J.2
  • 64
    • 0026730899 scopus 로고
    • The participation of nitric oxide in cell free- And its restriction of macrophage-mediated oxidation of low-density lipoprotein
    • Jessup W, Mohr D, Gieseg SP, Dean RT, Stocker R. The participation of nitric oxide in cell free- and its restriction of macrophage-mediated oxidation of low-density lipoprotein. Biochim Biophys Acta 1992; 1180:73-82.
    • (1992) Biochim Biophys Acta , vol.1180 , pp. 73-82
    • Jessup, W.1    Mohr, D.2    Gieseg, S.P.3    Dean, R.T.4    Stocker, R.5
  • 66
    • 0028293434 scopus 로고
    • Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine
    • Tsao PS, McEvoy LM, Drexler H, Butcher EC, Cooke JP. Enhanced endothelial adhesiveness in hypercholesterolemia is attenuated by L-arginine. Circulation 1994; 89:2176-2182.
    • (1994) Circulation , vol.89 , pp. 2176-2182
    • Tsao, P.S.1    McEvoy, L.M.2    Drexler, H.3    Butcher, E.C.4    Cooke, J.P.5
  • 67
    • 0028261621 scopus 로고
    • Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits
    • Cayatte AJ, Palacino JJ, Horten K, Cohen RA. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler Thromb 1994; 14:753-759.
    • (1994) Arterioscler Thromb , vol.14 , pp. 753-759
    • Cayatte, A.J.1    Palacino, J.J.2    Horten, K.3    Cohen, R.A.4
  • 68
    • 0025896795 scopus 로고
    • Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis
    • Cybulsky MI, Gimbrone MA Jr. Endothelial expression of a mononuclear leukocyte adhesion molecule during atherogenesis. Science 1991; 251:788-791.
    • (1991) Science , vol.251 , pp. 788-791
    • Cybulsky, M.I.1    Gimbrone M.A., Jr.2
  • 69
    • 0028353961 scopus 로고
    • Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leukocyte-induced endothelial dysfunction in porcine coronary arteries
    • Sugiyama S, Kugiyama K, Ohgushi M, Fujumoto K, Yasue H. Lysophosphatidylcholine in oxidized low-density lipoprotein increases endothelial susceptibility to polymorphonuclear leukocyte-induced endothelial dysfunction in porcine coronary arteries. Role of protein kinase C. Circ Res 1994; 74:565-575.
    • (1994) Role of Protein Kinase C. Circ Res , vol.74 , pp. 565-575
    • Sugiyama, S.1    Kugiyama, K.2    Ohgushi, M.3    Fujumoto, K.4    Yasue, H.5
  • 70
    • 0025731835 scopus 로고
    • Nitric oxide: An endogenous modulator of leukocyte adhesion
    • Kubes P, Suzuki M, Granger DN. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc Natl Acad Sci USA 1991; 88:4651-4655.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4651-4655
    • Kubes, P.1    Suzuki, M.2    Granger, D.N.3
  • 72
    • 0028314523 scopus 로고
    • Relation between coronary artery stenosis assessed by visual, caliper, and computer methods and exercise capacity in patients with single vessel coronary artery disease
    • Folland ED, Vogel RA, Hartigan P, Bates ER, Beauman GJ, Fortin T, et al. Relation between coronary artery stenosis assessed by visual, caliper, and computer methods and exercise capacity in patients with single vessel coronary artery disease. Circulation 1994; 89:2005-2014. The authors demonstrate that severity of stenosis is not correlated to severity of chronic ischemia.
    • (1994) Circulation , vol.89 , pp. 2005-2014
    • Folland, E.D.1    Vogel, R.A.2    Hartigan, P.3    Bates, E.R.4    Beauman, G.J.5    Fortin, T.6
  • 73
    • 0024590132 scopus 로고
    • Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis
    • Shimokawa H, Vanhoutte P. Impaired endothelium-dependent relaxation to aggregating platelets and related vasoactive substances in porcine coronary arteries in hypercholesterolemia and atherosclerosis. Circ Res 1989; 64:900-914.
    • (1989) Circ Res , vol.64 , pp. 900-914
    • Shimokawa, H.1    Vanhoutte, P.2
  • 74
    • 0023876496 scopus 로고
    • Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries
    • Forstermann U, Mugge A, Alheid U, Haverich A, Frolich JC. Selective attenuation of endothelium-mediated vasodilation in atherosclerotic human coronary arteries. Circ Res 1988; 62:185-190.
    • (1988) Circ Res , vol.62 , pp. 185-190
    • Forstermann, U.1    Mugge, A.2    Alheid, U.3    Haverich, A.4    Frolich, J.C.5
  • 75
    • 0023028215 scopus 로고
    • Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries
    • Ludmer PL, Selwyn AP, Shook TL, Wayne RR, Mudge GH, Alexander RW, et al. Paradoxical vasoconstriction induced by acetylcholine in atherosclerotic coronary arteries. N Engl J Med 1986; 315:1046-1051. Authors of this study demonstrated that endothelial dysfunction is present in the coronary arteries of patients with coronary artery disease. Intracoronary infusion of acetylcholine induced paradoxical vasoconstriction in patients with moderate and severe coronary artery stenoses and vasodilatation in normal vessels.
    • (1986) N Engl J Med , vol.315 , pp. 1046-1051
    • Ludmer, P.L.1    Selwyn, A.P.2    Shook, T.L.3    Wayne, R.R.4    Mudge, G.H.5    Alexander, R.W.6
  • 76
    • 0025015143 scopus 로고
    • The coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease
    • Vita JA, Treasure CB, Nabel EG, McLenachan JM, Fish RD, Yeung AD, et al. The coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 1990; 81:491-497. A clinical study in which coronary endothelial vasomotor dysfunction in patients with angiographically smooth coronary arteries was correlated to coronary risk factors such as serum cholesterol level, male sex, family medical history, age, and total number of risk factors.
    • (1990) Circulation , vol.81 , pp. 491-497
    • Vita, J.A.1    Treasure, C.B.2    Nabel, E.G.3    McLenachan, J.M.4    Fish, R.D.5    Yeung, A.D.6
  • 77
    • 0024536929 scopus 로고
    • Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease
    • Werns SW, Walton JA, Hsia HH, Nabel EG, Sanz ML, Pitt B. Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease. Circulation 1989; 79:287-291.
    • (1989) Circulation , vol.79 , pp. 287-291
    • Werns, S.W.1    Walton, J.A.2    Hsia, H.H.3    Nabel, E.G.4    Sanz, M.L.5    Pitt, B.6
  • 78
    • 0027262648 scopus 로고
    • Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans
    • Lefroy DC, Crake T, Uren NG, Davies GJ, Maseri A. Effect of inhibition of nitric oxide synthesis on epicardial coronary artery caliber and coronary blood flow in humans. Circulation 1993; 88:43-45.
    • (1993) Circulation , vol.88 , pp. 43-45
    • Lefroy, D.C.1    Crake, T.2    Uren, N.G.3    Davies, G.J.4    Maseri, A.5
  • 80
    • 0026093083 scopus 로고
    • Divergent effects of serotonin on coronary artery dimensions and blood flow in patients with coronary atherosclerosis and control patients
    • Golino P, Piscione F, Willerson JT, Cappelli-Bigazzi M, Focaccio A, Villari B, et al. Divergent effects of serotonin on coronary artery dimensions and blood flow in patients with coronary atherosclerosis and control patients. N Engl J Med 1991; 324:641-648.
    • (1991) N Engl J Med , vol.324 , pp. 641-648
    • Golino, P.1    Piscione, F.2    Willerson, J.T.3    Cappelli-Bigazzi, M.4    Focaccio, A.5    Villari, B.6
  • 83
    • 0027381832 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus
    • Johnstone MT, Creager SJ, Scales KM, Cusco JA, Lee BK, Creager MA. Impaired endothelium-dependent vasodilation in patients with insulin-dependent diabetes mellitus. Circulation 1993; 88:2510-2516.
    • (1993) Circulation , vol.88 , pp. 2510-2516
    • Johnstone, M.T.1    Creager, S.J.2    Scales, K.M.3    Cusco, J.A.4    Lee, B.K.5    Creager, M.A.6
  • 84
    • 0025307354 scopus 로고
    • Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans
    • Creager MA, Cooke JP, Mendelsohn ME, Gallagher SJ, Coleman SM, Loscalzo J, et al. Impaired vasodilation of forearm resistance vessels in hypercholesterolemic humans. J Clin Invest 1990; 86:228-234. Forearm resistance vasodilator responses to methacholine and nitroprusside in 13 patients with hypercholesterolemia were blunted compared with those in 11 normal subjects. This shows that the effect of nitrovasodilators, including endothelium-derived relaxing factor, on the vascular smooth muscle of resistance vessels is less than normal in humans with hypercholesterolemia.
    • (1990) J Clin Invest , vol.86 , pp. 228-234
    • Creager, M.A.1    Cooke, J.P.2    Mendelsohn, M.E.3    Gallagher, S.J.4    Coleman, S.M.5    Loscalzo, J.6
  • 85
    • 0025283892 scopus 로고
    • Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
    • Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE. Abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. N Engl J Med 1990; 323:22-27.
    • (1990) N Engl J Med , vol.323 , pp. 22-27
    • Panza, J.A.1    Quyyumi, A.A.2    Brush J.E., Jr.3    Epstein, S.E.4
  • 86
    • 0027445135 scopus 로고
    • The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients
    • Casino PR, Kilcoyne CM, Quyyumi AA, Hoeg JM, Panza JA. The role of nitric oxide in endothelium-dependent vasodilation of hypercholesterolemic patients. Circulation 1993; 88:2541-2547.
    • (1993) Circulation , vol.88 , pp. 2541-2547
    • Casino, P.R.1    Kilcoyne, C.M.2    Quyyumi, A.A.3    Hoeg, J.M.4    Panza, J.A.5
  • 87
    • 0002427958 scopus 로고    scopus 로고
    • Ultrasound assessment of endothelial vasomotor function
    • Lanzer P, Lipton M (editors): Berlin: Springer
    • Vita JA, Keaney JF Jr. Ultrasound assessment of endothelial vasomotor function. In: Lanzer P, Lipton M (editors): Diagnostics of vascular diseases: principals and technology. Berlin: Springer; 1996. pp. 249-259. This chapter describes the noninvasive method used to measure flow-mediated vasodilatation of peripheral arteries.
    • (1996) Diagnostics of Vascular Diseases: Principals and Technology , pp. 249-259
    • Vita, J.A.1    Keaney J.F., Jr.2
  • 88
    • 0030330268 scopus 로고    scopus 로고
    • Flow-induced vasodilation of the human brachial artery is impaired in patients < 40 years of age with coronary artery disease
    • Lieberman EH, Gerhard MD, Uehata A, Selwyn AP, Ganz P, Yeung AC, et al. Flow-induced vasodilation of the human brachial artery is impaired in patients < 40 years of age with coronary artery disease. Am J Cardiol 1996; 78:1210-1214. Ultrasound was used to demonstrate that flow-mediated vasodilatation in young patients with coronary artery disease was abnormal. Intra-arterial administration of L-NMMA was used to determine that the flow-mediated vasodilatation was mediated by EDRF.
    • (1996) Am J Cardiol , vol.78 , pp. 1210-1214
    • Lieberman, E.H.1    Gerhard, M.D.2    Uehata, A.3    Selwyn, A.P.4    Ganz, P.5    Yeung, A.C.6
  • 89
    • 0028957394 scopus 로고
    • Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo
    • Joannides R, Haefeli WE, Linder L, Richard V, Bakkali EH, Thuillez C, et al. Nitric oxide is responsible for flow-dependent dilatation of human peripheral conduit arteries in vivo. Circulation 1995; 91:1314-1319.
    • (1995) Circulation , vol.91 , pp. 1314-1319
    • Joannides, R.1    Haefeli, W.E.2    Linder, L.3    Richard, V.4    Bakkali, E.H.5    Thuillez, C.6
  • 91
    • 0028076232 scopus 로고
    • Estrogen improves endothelium-dependent, flow-mediated vasodilation in postmenopausal women
    • Lieberman EH, Gerhard MD, Uehata A, Walsh BW, Selwyn AP, Ganz P, et al. Estrogen improves endothelium-dependent, flow-mediated vasodilation in postmenopausal women. Ann Intern Med 1994; 121:936-941.
    • (1994) Ann Intern Med , vol.121 , pp. 936-941
    • Lieberman, E.H.1    Gerhard, M.D.2    Uehata, A.3    Walsh, B.W.4    Selwyn, A.P.5    Ganz, P.6
  • 92
    • 0009614964 scopus 로고
    • Flow-mediated vasodilation is impaired in the brachial artery of patients with coronary disease or diabetes mellitus
    • Lieberman EH, Uehata A, Polak J, Ganz P, Selwyn AP, Creager MA, et al. Flow-mediated vasodilation is impaired in the brachial artery of patients with coronary disease or diabetes mellitus [abstract]. Clin Res 1993; 41:217A.
    • (1993) Clin Res , vol.41
    • Lieberman, E.H.1    Uehata, A.2    Polak, J.3    Ganz, P.4    Selwyn, A.P.5    Creager, M.A.6
  • 93
    • 0028057273 scopus 로고
    • Impairment of endothelium-dependent dilation is an early event in children with familial hypercholesterolemia and is related to the lipoprotein[a] level
    • Sorensen KE, Celermajer DS, Georgakopoulos D, Hatcher G, Betteridge DJ, Deanfield JE. Impairment of endothelium-dependent dilation is an early event in children with familial hypercholesterolemia and is related to the lipoprotein[a] level. J Clin Invest 1994; 93:50-55.
    • (1994) J Clin Invest , vol.93 , pp. 50-55
    • Sorensen, K.E.1    Celermajer, D.S.2    Georgakopoulos, D.3    Hatcher, G.4    Betteridge, D.J.5    Deanfield, J.E.6
  • 95
    • 0022598190 scopus 로고
    • Vasoconstriction of stenotic coronary arteries during dynamic exercise in patients with classic angina pectoris: Reversibility by nitroglycerin
    • Gage JE, Hess OM, Murakami T, Ritter M, Grimm J, Krayenbuehl HP. Vasoconstriction of stenotic coronary arteries during dynamic exercise in patients with classic angina pectoris: reversibility by nitroglycerin. Circulation 1986; 73:865-875.
    • (1986) Circulation , vol.73 , pp. 865-875
    • Gage, J.E.1    Hess, O.M.2    Murakami, T.3    Ritter, M.4    Grimm, J.5    Krayenbuehl, H.P.6
  • 96
    • 0024356126 scopus 로고
    • Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise
    • Gordon JB, Ganz P, Nabel EG, Fish RD, Zebede J, Mudge GH, et al. Atherosclerosis influences the vasomotor response of epicardial coronary arteries to exercise. J Clin Invest 1989; 83:1946-1952.
    • (1989) J Clin Invest , vol.83 , pp. 1946-1952
    • Gordon, J.B.1    Ganz, P.2    Nabel, E.G.3    Fish, R.D.4    Zebede, J.5    Mudge, G.H.6
  • 97
    • 0026600628 scopus 로고
    • Patients with evidence of endothelial dysfunction as assessed by acetylcholine infusion demonstrate a marked increase in sensitivity to the constrictor effects of catecholamines
    • Vita JA, Treasure CB, Yeung AD, Vekshtein VI, Fantasia GM, Fish RD, et al. Patients with evidence of endothelial dysfunction as assessed by acetylcholine infusion demonstrate a marked increase in sensitivity to the constrictor effects of catecholamines. Circulation 1992; 85:1390-1397.
    • (1992) Circulation , vol.85 , pp. 1390-1397
    • Vita, J.A.1    Treasure, C.B.2    Yeung, A.D.3    Vekshtein, V.I.4    Fantasia, G.M.5    Fish, R.D.6
  • 98
    • 0026541706 scopus 로고
    • The pathogenesis of coronary artery disease and the acute coronary syndromes
    • Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992; 326:310-318.
    • (1992) N Engl J Med , vol.326 , pp. 310-318
    • Fuster, V.1    Badimon, L.2    Badimon, J.J.3    Chesebro, J.H.4
  • 99
    • 0024571655 scopus 로고
    • Transcardiac serotonin concentration is increased in selected patients with limiting angina and complex coronary lesion morphology
    • van den Berg EK, Schmitz JM, Benedict CR, Malloy CR, Willerson MH, Dehmer GJ. Transcardiac serotonin concentration is increased in selected patients with limiting angina and complex coronary lesion morphology. Circulation 1989; 79:116-124.
    • (1989) Circulation , vol.79 , pp. 116-124
    • Van den Berg, E.K.1    Schmitz, J.M.2    Benedict, C.R.3    Malloy, C.R.4    Willerson, M.H.5    Dehmer, G.J.6
  • 100
    • 0024344935 scopus 로고
    • Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications
    • Willerson JT, Golino P, Eidt J, Campbell WB, Buja LM. Specific platelet mediators and unstable coronary artery lesions. Experimental evidence and potential clinical implications. Circulation 1989; 80:198-205.
    • (1989) Circulation , vol.80 , pp. 198-205
    • Willerson, J.T.1    Golino, P.2    Eidt, J.3    Campbell, W.B.4    Buja, L.M.5
  • 101
    • 0028227750 scopus 로고
    • Vasoreactivity of the culprit lesion in unstable angina
    • Bogaty P, Hackett D, Davies G, Maseri A. Vasoreactivity of the culprit lesion in unstable angina. Circulation 1994; 90:5-11.
    • (1994) Circulation , vol.90 , pp. 5-11
    • Bogaty, P.1    Hackett, D.2    Davies, G.3    Maseri, A.4
  • 102
    • 0026575878 scopus 로고
    • Effect of acetylcholine on the highly stenotic coronary artery: Difference between the constrictor response of the infarct-related coronary artery and that of the noninfarct-related artery
    • Okumura K, Yasue H, Matsuyama K, Ogawa H, Morikami Y, Obata K, et al. Effect of acetylcholine on the highly stenotic coronary artery: difference between the constrictor response of the infarct-related coronary artery and that of the noninfarct-related artery. J Am Coll Cardiol 1992; 19:752-758.
    • (1992) J Am Coll Cardiol , vol.19 , pp. 752-758
    • Okumura, K.1    Yasue, H.2    Matsuyama, K.3    Ogawa, H.4    Morikami, Y.5    Obata, K.6
  • 103
    • 0029153361 scopus 로고
    • Atherosclerosis, oxidative stress and antioxidant protection in EDRF action
    • Keaney JF Jr, Vita JA. Atherosclerosis, oxidative stress and antioxidant protection in EDRF action. Prog Cardiovasc Dis 1995; 38:129-154. The authors review the role played by oxidative stress in the function of the vascular endothelium and examine the effects of treatment with antioxidants.
    • (1995) Prog Cardiovasc Dis , vol.38 , pp. 129-154
    • Keaney J.F., Jr.1    Vita, J.A.2
  • 104
    • 0025614563 scopus 로고
    • L-Arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits
    • Girerd XJ, Hirsch AT, Cooke JP, Dzau VJ, Creager MA. L-Arginine augments endothelium-dependent vasodilation in cholesterol-fed rabbits. Circ Res 1990; 67:1301-1308.
    • (1990) Circ Res , vol.67 , pp. 1301-1308
    • Girerd, X.J.1    Hirsch, A.T.2    Cooke, J.P.3    Dzau, V.J.4    Creager, M.A.5
  • 106
    • 0026338964 scopus 로고
    • Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine
    • Drexler H, Zeiher AM, Meinzer K, Just H. Correction of endothelial dysfunction in coronary microcirculation of hypercholesterolaemic patients by L-arginine. Lancet 1991; 338:1546-1550. Authors of this clinical study examined the effect of intracoronary infusion of L-arginine on coronary endothelial vasomotion in patients with hypercholesterolemia and in age-matched control subjects.
    • (1991) Lancet , vol.338 , pp. 1546-1550
    • Drexler, H.1    Zeiher, A.M.2    Meinzer, K.3    Just, H.4
  • 107
    • 0026629902 scopus 로고
    • Nitric oxide as a secretory product of mammalian cells
    • Nathan C. Nitric oxide as a secretory product of mammalian cells. FASEB 1992; 6:3051-3064.
    • (1992) FASEB , vol.6 , pp. 3051-3064
    • Nathan, C.1
  • 108
    • 0029670349 scopus 로고    scopus 로고
    • Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits
    • Bode-Boger SM, Boger RH, Kienke S, Junker W, Frohlich JC. Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits. Biochem Biophys Res Commun 1996; 219:598-603.
    • (1996) Biochem Biophys Res Commun , vol.219 , pp. 598-603
    • Bode-Boger, S.M.1    Boger, R.H.2    Kienke, S.3    Junker, W.4    Frohlich, J.C.5
  • 109
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P, Leone A, Calver A, Collier J, Moncada S. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 1992; 339:572-575.
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1    Leone, A.2    Calver, A.3    Collier, J.4    Moncada, S.5
  • 110
    • 0000166417 scopus 로고
    • Detection of superoxide generated by endothelial cells
    • Rosen GM, Greeman BA. Detection of superoxide generated by endothelial cells. Proc Natl Acad Sci USA 1984; 81:7269-7273.
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 7269-7273
    • Rosen, G.M.1    Greeman, B.A.2
  • 111
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor
    • Gryglewski RL, Palmer RM, Moncada S. Superoxide anion is involved in the breakdown of endothelium-derived vascular relaxing factor. Nature 1986; 320:454-456.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.L.1    Palmer, R.M.2    Moncada, S.3
  • 112
    • 0026034681 scopus 로고
    • Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity
    • Mugge A, Elwell JH, Peterson TE, Harrison DG. Release of intact endothelium-derived relaxing factor depends on endothelial superoxide dismutase activity. Am J Physiol 1991; 260:C219-C225.
    • (1991) Am J Physiol , vol.260
    • Mugge, A.1    Elwell, J.H.2    Peterson, T.E.3    Harrison, D.G.4
  • 113
    • 0027242030 scopus 로고
    • Hypercholesterolemia increases endothelial superoxide anion production
    • Ohara Y, Peterson TE, Harrison DG. Hypercholesterolemia increases endothelial superoxide anion production. J Clin Invest 1993; 91:2546-2551.
    • (1993) J Clin Invest , vol.91 , pp. 2546-2551
    • Ohara, Y.1    Peterson, T.E.2    Harrison, D.G.3
  • 114
    • 0029056560 scopus 로고
    • Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide production
    • Keaney JF Jr, Xu A, Cunningham D, Jackson T, Frei B, Vita JA. Dietary probucol preserves endothelial function in cholesterol-fed rabbits by limiting vascular oxidative stress and superoxide production. J Clin Invest 1995; 95:2520-2529. In this experiment dietary treatment with probucol, a lipid-soluble antioxidant, was used to preserve action of EDRF in animals fed cholesterol.
    • (1995) J Clin Invest , vol.95 , pp. 2520-2529
    • Keaney J.F., Jr.1    Xu, A.2    Cunningham, D.3    Jackson, T.4    Frei, B.5    Vita, J.A.6
  • 115
    • 0025989760 scopus 로고
    • Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxation in cholesterol-fed rabbits
    • Mugge A, Elwell JK, Peterson TE, Hofmayer TG, Heistad DD, Harrison DG. Chronic treatment with polyethylene-glycolated superoxide dismutase partially restores endothelium-dependent vascular relaxation in cholesterol-fed rabbits. Circ Res 1991; 69:1293-1399.
    • (1991) Circ Res , vol.69 , pp. 1293-1399
    • Mugge, A.1    Elwell, J.K.2    Peterson, T.E.3    Hofmayer, T.G.4    Heistad, D.D.5    Harrison, D.G.6
  • 116
    • 0009596593 scopus 로고
    • Superoxide dismutase restores endothelial vasodilator function in human coronary arteries in vivo
    • Meredith IT, Anderson TJ, Young AC, Lieberman EH, Dyce MC, Gonenne A, et al. Superoxide dismutase restores endothelial vasodilator function in human coronary arteries in vivo [abstract]. Circulation 1993; 88:1467.
    • (1993) Circulation , vol.88 , pp. 1467
    • Meredith, I.T.1    Anderson, T.J.2    Young, A.C.3    Lieberman, E.H.4    Dyce, M.C.5    Gonenne, A.6
  • 117
    • 0029986355 scopus 로고    scopus 로고
    • Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease
    • Levine GN, Frei B, Koulouris SN, Gerhard MD, Keaney JF Jr, Vita JA. Ascorbic acid reverses endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 1996; 93:1-7. In this placebo-controlled study flow-mediated vasodilatation of brachial artery was examined before and after oral administration of ascorbic acid.
    • (1996) Circulation , vol.93 , pp. 1-7
    • Levine, G.N.1    Frei, B.2    Koulouris, S.N.3    Gerhard, M.D.4    Keaney J.F., Jr.5    Vita, J.A.6
  • 118
    • 0029133481 scopus 로고
    • Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion
    • Pritchard KA Jr, Groszek L, Smalley DM, Sessa WC, Wu M, Villalon P, et al. Native low-density lipoprotein increases endothelial cell nitric oxide synthase generation of superoxide anion. Circ Res 1995; 77:510-518.
    • (1995) Circ Res , vol.77 , pp. 510-518
    • Pritchard K.A., Jr.1    Groszek, L.2    Smalley, D.M.3    Sessa, W.C.4    Wu, M.5    Villalon, P.6
  • 120
    • 0009563798 scopus 로고
    • The superoxide generating system in rabbit aorta resembles NAD[P]H oxidase
    • Pagano PJ, Ito Y, Tornheim K, Gallop P, Cohen RA. The superoxide generating system in rabbit aorta resembles NAD[P]H oxidase [abstract]. Circulation 1993; 88:1467.
    • (1993) Circulation , vol.88 , pp. 1467
    • Pagano, P.J.1    Ito, Y.2    Tornheim, K.3    Gallop, P.4    Cohen, R.A.5
  • 121
    • 0028179535 scopus 로고
    • Lysophosphatidylcholine increases vascular superoxide anion production via protein kinase C activation
    • Ohara Y, Peterson TE, Zheng B, Kuo JF, Harrison DG. Lysophosphatidylcholine increases vascular superoxide anion production via protein kinase C activation. Arterioscler Thromb 1994; 14:1007-1013.
    • (1994) Arterioscler Thromb , vol.14 , pp. 1007-1013
    • Ohara, Y.1    Peterson, T.E.2    Zheng, B.3    Kuo, J.F.4    Harrison, D.G.5
  • 122
    • 0019389783 scopus 로고
    • Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells
    • Weiss SJ, Young J, LoBuglio AF, Slivka A, Nimeh NF. Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells. J Clin Invest 1981; 68;714-722.
    • (1981) J Clin Invest , vol.68 , pp. 714-722
    • Weiss, S.J.1    Young, J.2    Lobuglio, A.F.3    Slivka, A.4    Nimeh, N.F.5
  • 123
    • 0025194004 scopus 로고
    • 2O2 and endothelium-dependent cerebral arteriolar dilation: Implications for the identity of endothelium-derived relaxing factor generated by acetylcholine
    • 2O2 and endothelium-dependent cerebral arteriolar dilation: implications for the identity of endothelium-derived relaxing factor generated by acetylcholine. Hypertension 1990; 16:162-169.
    • (1990) Hypertension , vol.16 , pp. 162-169
    • Wei, E.P.1    Kantos, H.E.2
  • 124
    • 0026502725 scopus 로고
    • Effects of oxidant stress on endothelium-derived relaxing factor-induced and nitrovasodilator-induced cGMP accumulation in vascular cells in culture
    • Marczin N, Ryan US, Catravas JD. Effects of oxidant stress on endothelium-derived relaxing factor-induced and nitrovasodilator-induced cGMP accumulation in vascular cells in culture. Circ Res 1992; 70:326-340.
    • (1992) Circ Res , vol.70 , pp. 326-340
    • Marczin, N.1    Ryan, U.S.2    Catravas, J.D.3
  • 125
    • 0031557659 scopus 로고    scopus 로고
    • A novel nonenzymatic pathway for the generation of nitric oxide by the reaction of hydrogen peroxide and D- Or L-arginine
    • Nagase S, Takemura K, Ueda A, Hirayama A, Aoyagi K, Kondoh M, et al. A novel nonenzymatic pathway for the generation of nitric oxide by the reaction of hydrogen peroxide and D- or L-arginine. Biochem Biophys Res Commun 1997; 233:150-153.
    • (1997) Biochem Biophys Res Commun , vol.233 , pp. 150-153
    • Nagase, S.1    Takemura, K.2    Ueda, A.3    Hirayama, A.4    Aoyagi, K.5    Kondoh, M.6
  • 126
    • 0026649212 scopus 로고
    • Stimulation of lipid peroxidation and hydroxyl radical generation by the contents of human atherosclerotic lesions
    • Smith C, Mitchinson MJ, Aruoma OI, Halliwell B. Stimulation of lipid peroxidation and hydroxyl radical generation by the contents of human atherosclerotic lesions. Biochem J 1992; 286:901-905.
    • (1992) Biochem J , vol.286 , pp. 901-905
    • Smith, C.1    Mitchinson, M.J.2    Aruoma, O.I.3    Halliwell, B.4
  • 127
    • 0020319120 scopus 로고
    • Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions
    • Fantone JD, Ward PA. Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions. Am J Pathol 1982; 107:397-403.
    • (1982) Am J Pathol , vol.107 , pp. 397-403
    • Fantone, J.D.1    Ward, P.A.2
  • 129
    • 0026782383 scopus 로고
    • Inactivation of a-1-proteinase inhibitor by peroxynitrite
    • Moreno JJ, Pryor WA. Inactivation of a-1-proteinase inhibitor by peroxynitrite. Chem Res Toxicol 1992; 5:425-431.
    • (1992) Chem Res Toxicol , vol.5 , pp. 425-431
    • Moreno, J.J.1    Pryor, W.A.2
  • 130
    • 0024455055 scopus 로고
    • N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor
    • Stamler JS, Mendelsohn ME, Amarante P, Smick D, Andon N, Davies PF, et al. N-acetylcysteine potentiates platelet inhibition by endothelium-derived relaxing factor. Circ Res 1989; 65:789-795.
    • (1989) Circ Res , vol.65 , pp. 789-795
    • Stamler, J.S.1    Mendelsohn, M.E.2    Amarante, P.3    Smick, D.4    Andon, N.5    Davies, P.F.6
  • 131
    • 0027286545 scopus 로고
    • NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties
    • Keaney FJ Jr, Simon DI, Stamler JS, Jaraki O, Scharfstein J, Vita JA, et al. NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties. J Clin Invest 1993; 91:1582-1589.
    • (1993) J Clin Invest , vol.91 , pp. 1582-1589
    • Keaney F.J., Jr.1    Simon, D.I.2    Stamler, J.S.3    Jaraki, O.4    Scharfstein, J.5    Vita, J.A.6
  • 132
    • 0003080942 scopus 로고
    • Hydroperoxides and thiol oxidants in the study of oxidative stress in intact cells and organs
    • Sites H (editor): London: Academic
    • Sies H. Hydroperoxides and thiol oxidants in the study of oxidative stress in intact cells and organs. In Sites H (editor): Oxidative stress: oxidants and antioxidants. London: Academic; 1985. pp. 73-91.
    • (1985) Oxidative Stress: Oxidants and Antioxidants , pp. 73-91
    • Sies, H.1
  • 133
    • 0009627006 scopus 로고
    • Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
    • Goldstein JL, Ho YK, Basu SK, Brown MS. Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc Natl Acad Sci USA 1979; 76:333-337.
    • (1979) Proc Natl Acad Sci USA , vol.76 , pp. 333-337
    • Goldstein, J.L.1    Ho, Y.K.2    Basu, S.K.3    Brown, M.S.4
  • 134
    • 0027157403 scopus 로고
    • Protective effect of 17β-estradiol against the cytotoxicity of minimally oxidized LDL to cultured bovine aortic endothelial cells
    • Negre-Salvayre A, Pieraggi MT, Mabile L, Salvayre R. Protective effect of 17β-estradiol against the cytotoxicity of minimally oxidized LDL to cultured bovine aortic endothelial cells. Atherosclerosis 1993; 99:207-217.
    • (1993) Atherosclerosis , vol.99 , pp. 207-217
    • Negre-Salvayre, A.1    Pieraggi, M.T.2    Mabile, L.3    Salvayre, R.4
  • 135
    • 0026570225 scopus 로고
    • Inactivation of endothelium-derived relaxing factor by oxidized lipoproteins
    • Chin JH, Azhar S, Hoffman BB. Inactivation of endothelium-derived relaxing factor by oxidized lipoproteins. J Clin Invest 1992; 89:10-18.
    • (1992) J Clin Invest , vol.89 , pp. 10-18
    • Chin, J.H.1    Azhar, S.2    Hoffman, B.B.3
  • 136
    • 0025286558 scopus 로고
    • Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins
    • Kugiyama K, Kerns SA, Morrisett JD, Roberts R, Henry PD. Impairment of endothelium-dependent arterial relaxation by lysolecithin in modified low-density lipoproteins. Nature 1990; 344:160-162.
    • (1990) Nature , vol.344 , pp. 160-162
    • Kugiyama, K.1    Kerns, S.A.2    Morrisett, J.D.3    Roberts, R.4    Henry, P.D.5
  • 137
    • 0026457242 scopus 로고
    • Lysophosphatidylcholine inhibits bradykinin-induced phosphoinositide hydrolysis and calcium transients in cultured bovine aortic endothelial cells
    • Inoue N, Hirata K, Yamada M, Hamamori Y, Matsuda Y, Akita H, et al. Lysophosphatidylcholine inhibits bradykinin-induced phosphoinositide hydrolysis and calcium transients in cultured bovine aortic endothelial cells. Circ Res 1992; 71:1410-1421.
    • (1992) Circ Res , vol.71 , pp. 1410-1421
    • Inoue, N.1    Hirata, K.2    Yamada, M.3    Hamamori, Y.4    Matsuda, Y.5    Akita, H.6
  • 138
    • 0022258987 scopus 로고
    • Evidence that lysolecithin is an important causal agent in atherosclerosis
    • Vidaver GA, Ting A, Lee JW. Evidence that lysolecithin is an important causal agent in atherosclerosis. J Theor Biol 1985; 115:27-41.
    • (1985) J Theor Biol , vol.115 , pp. 27-41
    • Vidaver, G.A.1    Ting, A.2    Lee, J.W.3
  • 141
    • 0026534718 scopus 로고
    • Oxidized low density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium
    • Boulanger CM, Tanner FC, Bea ML, Hahn AW, Werner A, Luscher TF. Oxidized low density lipoproteins induce mRNA expression and release of endothelin from human and porcine endothelium. Circ Res 1992; 70:1191-1197.
    • (1992) Circ Res , vol.70 , pp. 1191-1197
    • Boulanger, C.M.1    Tanner, F.C.2    Bea, M.L.3    Hahn, A.W.4    Werner, A.5    Luscher, T.F.6
  • 143
    • 0025215946 scopus 로고
    • Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta
    • Tesfamariam B, Brown ML, Deykin D, Cohen RA. Elevated glucose promotes generation of endothelium-derived vasoconstrictor prostanoids in rabbit aorta. J Clin Invest 1990; 85:929-932.
    • (1990) J Clin Invest , vol.85 , pp. 929-932
    • Tesfamariam, B.1    Brown, M.L.2    Deykin, D.3    Cohen, R.A.4
  • 144
    • 0025959096 scopus 로고
    • Ischemic heart disease and platelet aggregation: The Caerphilly Collaborative Heart Disease Study
    • Elwood PD, Renaud S, Sharp DS, Beswick AD, O'Brien JR, Yarnell WG. Ischemic heart disease and platelet aggregation: the Caerphilly Collaborative Heart Disease Study. Circulation 1991; 83:38-44.
    • (1991) Circulation , vol.83 , pp. 38-44
    • Elwood, P.D.1    Renaud, S.2    Sharp, D.S.3    Beswick, A.D.4    O'Brien, J.R.5    Yarnell, W.G.6
  • 145
    • 0029028967 scopus 로고
    • Von Willebrand factor, soluble P-selectin, tissue plasminogen activator and plasminogen activator inhibitor in atherosclerosis
    • Blann AD, Dobrotova M, Kubisz P, McCollum CN. von Willebrand factor, soluble P-selectin, tissue plasminogen activator and plasminogen activator inhibitor in atherosclerosis. Thromb Haemost 1995; 74:626-630.
    • (1995) Thromb Haemost , vol.74 , pp. 626-630
    • Blann, A.D.1    Dobrotova, M.2    Kubisz, P.3    McCollum, C.N.4
  • 146
    • 0025851332 scopus 로고
    • Oxidized low-density lipoprotein increases cultured human endothelial cell tissue factor activity and reduces protein C activation
    • Weis JR, Pitas RE, Wilson BD, Rodgers GM. Oxidized low-density lipoprotein increases cultured human endothelial cell tissue factor activity and reduces protein C activation. FASEB 1991; 5:2459-2469.
    • (1991) FASEB , vol.5 , pp. 2459-2469
    • Weis, J.R.1    Pitas, R.E.2    Wilson, B.D.3    Rodgers, G.M.4
  • 147
    • 0027250615 scopus 로고
    • Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells
    • Fryer RH, Wilson BD, Gubler DB, Fitzgerald LA, Rodgers GM. Homocysteine, a risk factor for premature vascular disease and thrombosis, induces tissue factor activity in endothelial cells. Arterioscler Thromb 1993; 13:1327-1333.
    • (1993) Arterioscler Thromb , vol.13 , pp. 1327-1333
    • Fryer, R.H.1    Wilson, B.D.2    Gubler, D.B.3    Fitzgerald, L.A.4    Rodgers, G.M.5
  • 149
    • 0023119612 scopus 로고
    • Fibrinopeptide A and platelet factor levels in unstable angina pectoris
    • Théroux P, Latour JG, Léger-Gauthier C, De Lara J. Fibrinopeptide A and platelet factor levels in unstable angina pectoris. Circulation 1987; 75:156-162.
    • (1987) Circulation , vol.75 , pp. 156-162
    • Théroux, P.1    Latour, J.G.2    Léger-Gauthier, C.3    De Lara, J.4
  • 150
    • 0019498337 scopus 로고
    • Hyperlipoproteinemia and reduced fibrinolytic activity in healthy coronary high-risk men
    • Andersen P, Arnesen J, Hjermann I. Hyperlipoproteinemia and reduced fibrinolytic activity in healthy coronary high-risk men. Acta Med Scand 1981; 209:199-202.
    • (1981) Acta Med Scand , vol.209 , pp. 199-202
    • Andersen, P.1    Arnesen, J.2    Hjermann, I.3
  • 151
    • 0027274074 scopus 로고
    • Endogenous tissue-type plasminogen-activator and risk of myocardial infarction
    • Ridker PM, Vaughan DE, Stampfer MJ, Manson JE, Hennekens CH. Endogenous tissue-type plasminogen-activator and risk of myocardial infarction. Lancet 1993; 341:1165-1168.
    • (1993) Lancet , vol.341 , pp. 1165-1168
    • Ridker, P.M.1    Vaughan, D.E.2    Stampfer, M.J.3    Manson, J.E.4    Hennekens, C.H.5
  • 152
    • 0022354051 scopus 로고
    • Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction
    • Hamsten A, Wiman BB, de Faire U, Blomback M. Increased plasma levels of a rapid inhibitor of tissue plasminogen activator in young survivors of myocardial infarction. N Engl J Med 1985; 313:1557-1563.
    • (1985) N Engl J Med , vol.313 , pp. 1557-1563
    • Hamsten, A.1    Wiman, B.B.2    De Faire, U.3    Blomback, M.4
  • 153
    • 0023185776 scopus 로고
    • Plasminogen activator inhibitor in plasma: Risk factor for recurrent myocardial infarction
    • Hamsten A, deFaire U, Walldius G, Dahlen G, Szamosi A, Landou C, et al. Plasminogen activator inhibitor in plasma: risk factor for recurrent myocardial infarction. Lancet 1987; 2:3-9.
    • (1987) Lancet , vol.2 , pp. 3-9
    • Hamsten, A.1    Defaire, U.2    Walldius, G.3    Dahlen, G.4    Szamosi, A.5    Landou, C.6
  • 154
    • 0027291105 scopus 로고
    • Transferable lipids in oxidized low-density lipoprotein stimulate plasminogen activator inhibitor-1 and inhibit tissue-type plasminogen activator release from endothelial cells
    • Kugiyama K, Sakamoto T, Misumi I, Sugiyama S, Ohgushi M, Ogawa H, et al. Transferable lipids in oxidized low-density lipoprotein stimulate plasminogen activator inhibitor-1 and inhibit tissue-type plasminogen activator release from endothelial cells. Circ Res 1993; 73:335-343.
    • (1993) Circ Res , vol.73 , pp. 335-343
    • Kugiyama, K.1    Sakamoto, T.2    Misumi, I.3    Sugiyama, S.4    Ohgushi, M.5    Ogawa, H.6
  • 155
    • 0009614967 scopus 로고
    • Angiotensin II induces plasminogen activator inhibitor-1 [PAI-1] synthesis in vitro
    • Vaughan DE, Shen C, Lazos S. Angiotensin II induces plasminogen activator inhibitor-1 [PAI-1] synthesis in vitro [abstract]. Circulation 1992; 86 (suppl 1):1557.
    • (1992) Circulation , vol.86 , Issue.SUPPL. 1 , pp. 1557
    • Vaughan, D.E.1    Shen, C.2    Lazos, S.3
  • 156
    • 0027267328 scopus 로고
    • Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function
    • Ridker PM, Gavoury CL, Conlin PR, Seely EW, Williams GH, Vaughan DE. Stimulation of plasminogen activator inhibitor in vivo by infusion of angiotensin II. Evidence of a potential interaction between the renin-angiotensin system and fibrinolytic function. Circulation 1993; 87:1969-1973.
    • (1993) Circulation , vol.87 , pp. 1969-1973
    • Ridker, P.M.1    Gavoury, C.L.2    Conlin, P.R.3    Seely, E.W.4    Williams, G.H.5    Vaughan, D.E.6
  • 157
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: Results of the Survival and Ventricular Enlargement Trial
    • Pfeffer MA, Braunwald E, Moye LA, Basta L, Brown EJ, Cuddy TE, et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction: results of the Survival and Ventricular Enlargement Trial. N Engl J Med 1992; 327:669-677.
    • (1992) N Engl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3    Basta, L.4    Brown, E.J.5    Cuddy, T.E.6
  • 158
    • 0025794059 scopus 로고
    • Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension
    • Alderman MH, Madhaven S, Ooi WL, Cohen H, Sealey JH, Laragh JH. Association of the renin-sodium profile with the risk of myocardial infarction in patients with hypertension. N Engl J Med 1991; 324:1098-1104.
    • (1991) N Engl J Med , vol.324 , pp. 1098-1104
    • Alderman, M.H.1    Madhaven, S.2    Ooi, W.L.3    Cohen, H.4    Sealey, J.H.5    Laragh, J.H.6
  • 159
    • 0031023733 scopus 로고    scopus 로고
    • L-Arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice
    • Aji W, Ravalli S, Szabolcs M, Jiang X, Sciacca RR, Michler RE, et al. L-Arginine prevents xanthoma development and inhibits atherosclerosis in LDL receptor knockout mice. Circulation 1997; 95:430-437.
    • (1997) Circulation , vol.95 , pp. 430-437
    • Aji, W.1    Ravalli, S.2    Szabolcs, M.3    Jiang, X.4    Sciacca, R.R.5    Michler, R.E.6
  • 161
    • 0027193894 scopus 로고
    • Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion
    • Collins T. Endothelial nuclear factor-κB and the initiation of the atherosclerotic lesion. Lab Invest 1993; 68:499-508.
    • (1993) Lab Invest , vol.68 , pp. 499-508
    • Collins, T.1
  • 162
    • 0028349237 scopus 로고
    • Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells
    • Kume N, Gimbrone MA. Lysophosphatidylcholine transcriptionally induces growth factor gene expression in cultured human endothelial cells. J Clin Invest 1994; 93:907-911.
    • (1994) J Clin Invest , vol.93 , pp. 907-911
    • Kume, N.1    Gimbrone, M.A.2
  • 163
  • 164
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian Simvastatin Survival Study [4S]
    • Scandinavian Simvastatin Survival Study Group
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study [4S]. Lancet 1994; 344:1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 165
    • 0025183769 scopus 로고
    • Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B
    • Brown G, Albers JJ, Fisher LD, Schaefer SM, Lin JT, Kaplan C, et al. Regression of coronary artery disease as a result of intensive lipid-lowering therapy in men with high levels of apolipoprotein B. N Engl J Med 1990; 323:1289-1298.
    • (1990) N Engl J Med , vol.323 , pp. 1289-1298
    • Brown, G.1    Albers, J.J.2    Fisher, L.D.3    Schaefer, S.M.4    Lin, J.T.5    Kaplan, C.6
  • 166
    • 0025051359 scopus 로고
    • Regression of coronary atherosclerosis
    • Loscalzo J. Regression of coronary atherosclerosis. N Engl J Med 1990; 323:1337-1339.
    • (1990) N Engl J Med , vol.323 , pp. 1337-1339
    • Loscalzo, J.1
  • 167
    • 0029650740 scopus 로고
    • Cholesterol reduction in cardiovascular disease: Clinical benefits and possible mechanisms
    • Levine GN, Keaney JF Jr, Vita JA. Cholesterol reduction in cardiovascular disease: clinical benefits and possible mechanisms. N Engl J Med 1995;
    • (1995) N Engl J Med , vol.332 , pp. 512-521
    • Levine, G.N.1    Keaney J.F., Jr.2    Vita, J.A.3
  • 168
    • 0027191073 scopus 로고
    • Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolaemic patients
    • Leung WH, Lau CP, Waong CK. Beneficial effect of cholesterol-lowering therapy on coronary endothelium-dependent relaxation in hypercholesterolaemic patients. Lancet 1993; 341:1496-1500.
    • (1993) Lancet , vol.341 , pp. 1496-1500
    • Leung, W.H.1    Lau, C.P.2    Waong, C.K.3
  • 169
    • 0028910272 scopus 로고
    • Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease
    • Treasure CB, Klein JL, Weintraub WS, Talley JD, Stillabower ME, Kosinski AS, et al. Beneficial effects of cholesterol-lowering therapy on the coronary endothelium in patients with coronary artery disease. N Engl J Med 1995; 332:481-487. Authors of this placebo-controlled study investigated the effect of lipid-level-lowering therapy on endothelial function of coronary artery. Cholesterol-level lowering with lovastatin significantly improved endothelium-mediated responses in the coronary arteries of patients with atherosclerosis.
    • (1995) N Engl J Med , vol.332 , pp. 481-487
    • Treasure, C.B.1    Klein, J.L.2    Weintraub, W.S.3    Talley, J.D.4    Stillabower, M.E.5    Kosinski, A.S.6
  • 170
    • 0028939363 scopus 로고
    • The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion
    • Anderson TJ, Meredith IT, Yeung AC, Frei B, Selwyn AP, Ganz P. The effect of cholesterol-lowering and antioxidant therapy on endothelium-dependent coronary vasomotion. N Engl J Med 1995; 332:488-493. Authors of this randomized trial showed that addition of antioxidant therapy (probucol) to lipid-level-lowering therapy resulted in greater improvement in coronary endothelial vasomotor function.
    • (1995) N Engl J Med , vol.332 , pp. 488-493
    • Anderson, T.J.1    Meredith, I.T.2    Yeung, A.C.3    Frei, B.4    Selwyn, A.P.5    Ganz, P.6
  • 173
    • 0029925181 scopus 로고    scopus 로고
    • Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS)
    • Stephens NG, Parsons A, Schofield PM, Kelly F, Cheeseman K, Mitchinson MJ. Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS). Lancet 1996; 347:781-786. A randomized, placebo-controlled trial of vitamin E (400-800 1U/day) treatment of patients known to have coronary artery disease. Authors of this study found a 77% reduction in incidence of nonfatal myocardial infarction and a 47% reduction in numbers of deaths and nonfatal infarctions.
    • (1996) Lancet , vol.347 , pp. 781-786
    • Stephens, N.G.1    Parsons, A.2    Schofield, P.M.3    Kelly, F.4    Cheeseman, K.5    Mitchinson, M.J.6
  • 174
    • 0030916162 scopus 로고    scopus 로고
    • Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction
    • Rapola JM, Virtamo J, Ripatti S, Huttunen JK, Albanes D, Taylor PR, et al. Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence of major coronary events in men with previous myocardial infarction. Lancet 1997; 349:1715-1720. In this primary prevention trial male smokers were randomly allocated vitamin E, β-carotene, both, or placebo, and evaluated for the development of lung cancer, other cancers, and overall mortality according to causes of death.
    • (1997) Lancet , vol.349 , pp. 1715-1720
    • Rapola, J.M.1    Virtamo, J.2    Ripatti, S.3    Huttunen, J.K.4    Albanes, D.5    Taylor, P.R.6
  • 176
    • 0030036853 scopus 로고    scopus 로고
    • Vascular incorporation of alpha- Tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation
    • Keaney JF Jr, Guo Y, Cunningham D. Vascular incorporation of alpha- tocopherol prevents endothelial dysfunction due to oxidized LDL by inhibiting protein kinase C stimulation. J Clin Invest 1996; 98:386-394.
    • (1996) J Clin Invest , vol.98 , pp. 386-394
    • Keaney J.F., Jr.1    Guo, Y.2    Cunningham, D.3
  • 177
    • 0030034465 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin dependent diabetes mellitus
    • Ting HH, Timimi FK, Boles KS, Creager SJ, Ganz P, Creager MA. Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin dependent diabetes mellitus. J Clin Invest 1996; 97:22-28.
    • (1996) J Clin Invest , vol.97 , pp. 22-28
    • Ting, H.H.1    Timimi, F.K.2    Boles, K.S.3    Creager, S.J.4    Ganz, P.5    Creager, M.A.6
  • 178
    • 0030782969 scopus 로고    scopus 로고
    • Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients
    • Solzbach U, Hornig B, Jeserich M, Just H. Vitamin C improves endothelial dysfunction of epicardial coronary arteries in hypertensive patients. Circulation 1997; 96:1513-1519.
    • (1997) Circulation , vol.96 , pp. 1513-1519
    • Solzbach, U.1    Hornig, B.2    Jeserich, M.3    Just, H.4
  • 179
    • 84941081303 scopus 로고
    • Nonenzymatic antioxidant defense systems
    • Frei B (editor): San Diego: Academic Press
    • Briviba K, Sies H. Nonenzymatic antioxidant defense systems. In Frei B (editor): Natural antioxidants in human health and disease. San Diego: Academic Press; 1994. pp. 107-128.
    • (1994) Natural Antioxidants in Human Health and Disease , pp. 107-128
    • Briviba, K.1    Sies, H.2
  • 180
    • 0027508999 scopus 로고
    • Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- Rather than pro-oxidant activity of vitamin C in the presence of transition metal ions
    • Retsky KL, Freeman MW, Frei B. Ascorbic acid oxidation product(s) protect human low density lipoprotein against atherogenic modification. Anti- rather than pro-oxidant activity of vitamin C in the presence of transition metal ions. J Biol Chem 1993; 268:1304-1309.
    • (1993) J Biol Chem , vol.268 , pp. 1304-1309
    • Retsky, K.L.1    Freeman, M.W.2    Frei, B.3
  • 181
    • 0025325753 scopus 로고
    • Physiologic levels of ascorbate inhibit oxidative modification of low density lipoprotein
    • Jialal I, Vega GL, Grundy SM. Physiologic levels of ascorbate inhibit oxidative modification of low density lipoprotein. Atherosclerosis 1990; 82:185-191.
    • (1990) Atherosclerosis , vol.82 , pp. 185-191
    • Jialal, I.1    Vega, G.L.2    Grundy, S.M.3
  • 182
    • 0028263767 scopus 로고
    • Glutathione-ascorbic acid antioxidant system in animals
    • Meister A. Glutathione-ascorbic acid antioxidant system in animals. J Biol Chem 1994; 269:9397-9400.
    • (1994) J Biol Chem , vol.269 , pp. 9397-9400
    • Meister, A.1
  • 183
    • 0027660945 scopus 로고
    • Nitric oxide synthesis is impaired in glutathione-depleted human umbilical vein endothelial cells
    • Ghigo D, Alessio P, Foco A, Bussolino F, Costamagna C, Heller R, et al. Nitric oxide synthesis is impaired in glutathione-depleted human umbilical vein endothelial cells. Am J Physiol 1993; 265:C728-C732.
    • (1993) Am J Physiol , vol.265
    • Ghigo, D.1    Alessio, P.2    Foco, A.3    Bussolino, F.4    Costamagna, C.5    Heller, R.6
  • 184
    • 0028926830 scopus 로고
    • The role of thiols in the apparent activation of rat brain nitric oxide synthase (NOS)
    • Komori Y, Hyun J, Chiang K, Fukuto JM. The role of thiols in the apparent activation of rat brain nitric oxide synthase (NOS). J Biochem 1995; 117:923-927.
    • (1995) J Biochem , vol.117 , pp. 923-927
    • Komori, Y.1    Hyun, J.2    Chiang, K.3    Fukuto, J.M.4
  • 185
    • 0032521146 scopus 로고    scopus 로고
    • L-2-oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary disease
    • Vita JA, Frei B, Holbrook M, Gokce N, Leaf C, Keaney JF. L-2-oxothiazolidine-4-carboxylic acid reverses endothelial dysfunction in patients with coronary disease. J Clin Invest 1998; 101:1408-1414.
    • (1998) J Clin Invest , vol.101 , pp. 1408-1414
    • Vita, J.A.1    Frei, B.2    Holbrook, M.3    Gokce, N.4    Leaf, C.5    Keaney, J.F.6
  • 186
    • 0031017903 scopus 로고    scopus 로고
    • N-acetylcysteine does not influence the activity of endothelium-derived relaxing factor in vivo
    • Creager MA, Roddy MA, Boles K, Stamler JS. N-acetylcysteine does not influence the activity of endothelium-derived relaxing factor in vivo. Hypertension 1997; 29:668-672.
    • (1997) Hypertension , vol.29 , pp. 668-672
    • Creager, M.A.1    Roddy, M.A.2    Boles, K.3    Stamler, J.S.4
  • 187
    • 0025755590 scopus 로고
    • Estrogen and coronary heart disease in women
    • Barrett-Connor E, Bush TL. Estrogen and coronary heart disease in women. JAMA 1991; 265:1861-1867.
    • (1991) JAMA , vol.265 , pp. 1861-1867
    • Barrett-Connor, E.1    Bush, T.L.2
  • 188
    • 0025940856 scopus 로고
    • Post-menopausal estrogen therapy and cardiovascular disease: Ten-year follow-up from the Nurses' Health Study
    • Stampfer MJ, Colditz GA, Willett WC, Manson JE, Rosner B, Speizer FE, et al. Post-menopausal estrogen therapy and cardiovascular disease: ten-year follow-up from the Nurses' Health Study. N Engl J Med 1991; 325:756-762.
    • (1991) N Engl J Med , vol.325 , pp. 756-762
    • Stampfer, M.J.1    Colditz, G.A.2    Willett, W.C.3    Manson, J.E.4    Rosner, B.5    Speizer, F.E.6
  • 190
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women
    • Heart and Estrogen/Progestin Replacement Study (HERS) Research Group
    • Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/Progestin Replacement Study (HERS) Research Group. J Am Med Assoc 1998; 280:605-613.
    • (1998) J Am Med Assoc , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3    Furberg, C.4    Herrington, D.5    Riggs, B.6
  • 191
    • 0023265766 scopus 로고
    • Cardiovascular mortality and noncontraceptive use of estrogen in women: Results from the Lipid Research Clinics Program Follow-up Study
    • Bush TL, Barrett-Connor E, Cowan LD, Criqui MH, Wallace RB, Suchindran CM, et al. Cardiovascular mortality and noncontraceptive use of estrogen in women: results from the Lipid Research Clinics Program Follow-up Study. Circulation 1987; 75:1102-1109.
    • (1987) Circulation , vol.75 , pp. 1102-1109
    • Bush, T.L.1    Barrett-Connor, E.2    Cowan, L.D.3    Criqui, M.H.4    Wallace, R.B.5    Suchindran, C.M.6
  • 192
    • 0028176129 scopus 로고
    • 17β-estradiol preserves endothelial vasodilator function and limits LDL oxidation in hypercholesterolemic swine
    • Keaney JF Jr, Shwaery GT, Xu A, Nicolosi RJ, Loscalzo J, Foxall TL, et al. 17β-Estradiol preserves endothelial vasodilator function and limits LDL oxidation in hypercholesterolemic swine. Circulation 1994; 89:2251-2259.
    • (1994) Circulation , vol.89 , pp. 2251-2259
    • Keaney J.F., Jr.1    Shwaery, G.T.2    Xu, A.3    Nicolosi, R.J.4    Loscalzo, J.5    Foxall, T.L.6
  • 193
    • 0345662351 scopus 로고    scopus 로고
    • Long-term estradiol therapy with or without progesterone improves endothelium dependent vasodilatation in post-menopausal women
    • Gerhard MD, Tawakol A, Halley EA. Long-term estradiol therapy with or without progesterone improves endothelium dependent vasodilatation in post-menopausal women [abstract]. Circulation 1996; 94 (suppl 1):1279.
    • (1996) Circulation , vol.94 , Issue.SUPPL. 1 , pp. 1279
    • Gerhard, M.D.1    Tawakol, A.2    Halley, E.A.3
  • 194
    • 0028154102 scopus 로고
    • Ethinyl estradiol acutely attenuates abnormal coronary vasomotor responses to acetylcholine in post-menopausal women
    • Reis SE, Gloth ST, Blumenthal RS, Resar JR, Zacur HA, Gerstenblith G, et al. Ethinyl estradiol acutely attenuates abnormal coronary vasomotor responses to acetylcholine in post-menopausal women. Circulation 1994; 89:52-60.
    • (1994) Circulation , vol.89 , pp. 52-60
    • Reis, S.E.1    Gloth, S.T.2    Blumenthal, R.S.3    Resar, J.R.4    Zacur, H.A.5    Gerstenblith, G.6
  • 195
    • 0026774098 scopus 로고
    • Acute effect of 17β-estradiol on rabbit coronary artery contractile responses to endothelin-1
    • Jiang C, Sarrel PM, Poole-Wilson PA, Collins P. Acute effect of 17β-estradiol on rabbit coronary artery contractile responses to endothelin-1. Am J Pnysiol 1992; 263:H271-H275.
    • (1992) Am J Pnysiol , vol.263
    • Jiang, C.1    Sarrel, P.M.2    Poole-Wilson, P.A.3    Collins, P.4
  • 196
    • 0027475199 scopus 로고
    • The association of changes in physical-activity level and other lifestyle characteristics with mortality among men
    • Paffenbarger RS, Hyde RT, Wing AL, Lee IM, Jung D, Kampert JB. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med 1993; 328:538-545.
    • (1993) N Engl J Med , vol.328 , pp. 538-545
    • Paffenbarger, R.S.1    Hyde, R.T.2    Wing, A.L.3    Lee, I.M.4    Jung, D.5    Kampert, J.B.6
  • 198
    • 0028922064 scopus 로고
    • Changes in physical fitness and all-cause mortality: A prospective study of healthy and unhealthy men
    • Blair SN, Kohn HW III, Barlow CE, Paffenbarger RS, Gibbons LW, Macera CA. Changes in physical fitness and all-cause mortality: a prospective study of healthy and unhealthy men. JAMA 1995; 273:1093-1098.
    • (1995) JAMA , vol.273 , pp. 1093-1098
    • Blair, S.N.1    Kohn H.W. III2    Barlow, C.E.3    Paffenbarger, R.S.4    Gibbons, L.W.5    Macera, C.A.6
  • 199
    • 0027491127 scopus 로고
    • Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs
    • Wang J, Wolin MS, Hintze TH. Chronic exercise enhances endothelium-mediated dilation of epicardial coronary artery in conscious dogs. Circ Res 1993; 73:829-838.
    • (1993) Circ Res , vol.73 , pp. 829-838
    • Wang, J.1    Wolin, M.S.2    Hintze, T.H.3
  • 200
    • 0028274298 scopus 로고
    • Vasodilator responses of coronary resistance arteries of exercise-trained pigs
    • Muller JM, Meyers PR, Laughlin H. Vasodilator responses of coronary resistance arteries of exercise-trained pigs. Circulation 1994; 89:2308-2314.
    • (1994) Circulation , vol.89 , pp. 2308-2314
    • Muller, J.M.1    Meyers, P.R.2    Laughlin, H.3
  • 201
    • 0001639938 scopus 로고    scopus 로고
    • Exercise training enhances endothelial function in young men
    • Clarkson P, Montgomery H, Donald A, Powe A, Bull T, Dollery C, et al. Exercise training enhances endothelial function in young men [abstract]. J Am Coll Cardiol 1996; 27 (suppl A):288A. A brachial artery ultrasound technique is used to measure endothelium-dependent flow in young healthy men as a function of physical training. Results of this study showed that training enhanced endothelial function in young men of average fitness, even in the presence of cardiac risk factors.
    • (1996) J Am Coll Cardiol , vol.27 , Issue.SUPPL. A
    • Clarkson, P.1    Montgomery, H.2    Donald, A.3    Powe, A.4    Bull, T.5    Dollery, C.6
  • 202
    • 0028138817 scopus 로고
    • Ischemia, hyperemia, exercise, and nitric oxide: Complex physiology and complex molecular adaptations
    • Loscalzo J, Vita JA. Ischemia, hyperemia, exercise, and nitric oxide: complex physiology and complex molecular adaptations. Circulation 1994; 90:2285-2290.
    • (1994) Circulation , vol.90 , pp. 2285-2290
    • Loscalzo, J.1    Vita, J.A.2
  • 203
    • 9444280103 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease
    • Mancini GB, Henry GC, Macaya C, O'Neill BJ, Pucillo AL, Carere RG, et al. Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. Circulation 1996; 94:258-265.
    • (1996) Circulation , vol.94 , pp. 258-265
    • Mancini, G.B.1    Henry, G.C.2    Macaya, C.3    O'Neill, B.J.4    Pucillo, A.L.5    Carere, R.G.6
  • 204
    • 0028955316 scopus 로고
    • Characterization and functional analysis of the rat endothelin-1 promoter
    • Paul M, Zintz M, Bocker W, Dyer M. Characterization and functional analysis of the rat endothelin-1 promoter. Hypertension 1995; 25:683-693.
    • (1995) Hypertension , vol.25 , pp. 683-693
    • Paul, M.1    Zintz, M.2    Bocker, W.3    Dyer, M.4
  • 205
    • 0006862091 scopus 로고    scopus 로고
    • Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans
    • Horning B, Kohler C, Drexler H. Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans. Circulation 1997; 95:1115-1118
    • (1997) Circulation , vol.95 , pp. 1115-1118
    • Horning, B.1    Kohler, C.2    Drexler, H.3
  • 206
    • 0026016241 scopus 로고
    • Reversal of hypercholesterolemia-induced endothelial dysfunction by L-arginine
    • Rubanyi GM. Reversal of hypercholesterolemia-induced endothelial dysfunction by L-arginine. Circulation 1991; 83:1118-1120.
    • (1991) Circulation , vol.83 , pp. 1118-1120
    • Rubanyi, G.M.1
  • 207
    • 15844389652 scopus 로고
    • Oral L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans
    • Clarkson P, Adams MR, Powe AJ. Oral L-arginine improves endothelium-dependent vasodilation in hypercholesterolemic humans. J Clin Invest 1994; 67:1989-1994.
    • (1994) J Clin Invest , vol.67 , pp. 1989-1994
    • Clarkson, P.1    Adams, M.R.2    Powe, A.J.3
  • 208
    • 0031018333 scopus 로고    scopus 로고
    • Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans
    • Tawakol A, Omland T, Gerhard M, Wu J, Creager MA. Hyperhomocyst(e)inemia is associated with impaired endothelium-dependent vasodilation in humans. Circulation 1997; 95:1119-1121.
    • (1997) Circulation , vol.95 , pp. 1119-1121
    • Tawakol, A.1    Omland, T.2    Gerhard, M.3    Wu, J.4    Creager, M.A.5
  • 211
    • 0022995989 scopus 로고
    • Vitamin C increases the prostacyclin production and decreases the vascular lesions in experimental atherosclerosis in rabbits
    • Beetens JR, Coene MC, Beheyen A, Zonnekenyn L, Herman AG. Vitamin C increases the prostacyclin production and decreases the vascular lesions in experimental atherosclerosis in rabbits. Prostaglandins 1986; 32:334-352.
    • (1986) Prostaglandins , vol.32 , pp. 334-352
    • Beetens, J.R.1    Coene, M.C.2    Beheyen, A.3    Zonnekenyn, L.4    Herman, A.G.5
  • 212
    • 0029846809 scopus 로고    scopus 로고
    • Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism
    • Freedman JE, Farhat JH, Lock JM, Loscalzo J, Keaney JF Jr. Alpha-tocopherol inhibits aggregation of human platelets by a protein kinase C-dependent mechanism. Circulation 1996; 94:2434-2440.
    • (1996) Circulation , vol.94 , pp. 2434-2440
    • Freedman, J.E.1    Farhat, J.H.2    Lock, J.M.3    Loscalzo, J.4    Keaney J.F., Jr.5
  • 213
    • 0022969424 scopus 로고
    • Inhibition of platelet aggregability by moderate-intensity physical exercise; A randomized clinical trial in overweight men
    • Rauramaa R, Salonen JT, Seppanen K, Salonen R, Venalainen JM, Ihanainen M, et al. Inhibition of platelet aggregability by moderate-intensity physical exercise; a randomized clinical trial in overweight men. Circulation 1986; 74:939-944.
    • (1986) Circulation , vol.74 , pp. 939-944
    • Rauramaa, R.1    Salonen, J.T.2    Seppanen, K.3    Salonen, R.4    Venalainen, J.M.5    Ihanainen, M.6
  • 214
    • 0026667957 scopus 로고
    • Effects on platelet aggregation and fibrinolytic activity during upright posture and exercise in healthy men
    • Winther K, Hillegass W, Tofler GH, Jimenez A, Brezinski DA, Schafer AI, et al. Effects on platelet aggregation and fibrinolytic activity during upright posture and exercise in healthy men. Am J Cardiol 1992; 70:1051-1055.
    • (1992) Am J Cardiol , vol.70 , pp. 1051-1055
    • Winther, K.1    Hillegass, W.2    Tofler, G.H.3    Jimenez, A.4    Brezinski, D.A.5    Schafer, A.I.6
  • 215
    • 0031051122 scopus 로고    scopus 로고
    • Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans
    • Wolf A, Zalpour C, Theilmeier G, Wang B, Ma A, Anderson B, et al. Dietary L-arginine supplementation normalizes platelet aggregation in hypercholesterolemic humans. J Am Coll Cardiol 1997; 29:479-485.
    • (1997) J Am Coll Cardiol , vol.29 , pp. 479-485
    • Wolf, A.1    Zalpour, C.2    Theilmeier, G.3    Wang, B.4    Ma, A.5    Anderson, B.6
  • 216
    • 0009060192 scopus 로고    scopus 로고
    • Effects of hormone-replacement therapy on fibrinolysis in postmenopausal women
    • Koh KK, Mincenoyer R, Bui MN, Csako G, Pucino F, Guetta V, et al. Effects of hormone-replacement therapy on fibrinolysis in postmenopausal women. N Engl J Med 1997; 336:683-690.
    • (1997) N Engl J Med , vol.336 , pp. 683-690
    • Koh, K.K.1    Mincenoyer, R.2    Bui, M.N.3    Csako, G.4    Pucino, F.5    Guetta, V.6
  • 217
    • 0025810225 scopus 로고
    • Effects of physical conditioning on fibrinolytic variables in young and old healthy adults
    • Stratton JR, Chandler WL, Schwartz RS, Cerqueira MD, Levy WC, Kahn SE, et al. Effects of physical conditioning on fibrinolytic variables in young and old healthy adults. Circulation 1991; 83:1692-1697. Strenuous exercise for 6 months improved fibrinolytic parameters in healthy old subjects.
    • (1991) Circulation , vol.83 , pp. 1692-1697
    • Stratton, J.R.1    Chandler, W.L.2    Schwartz, R.S.3    Cerqueira, M.D.4    Levy, W.C.5    Kahn, S.E.6
  • 218
    • 0028167636 scopus 로고
    • Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells
    • Faruqi R, De La Motte C, Dicorleto PE. Alpha-tocopherol inhibits agonist-induced monocytic cell adhesion to cultured human endothelial cells. J Clin Invest 1994; 94:592-600.
    • (1994) J Clin Invest , vol.94 , pp. 592-600
    • Faruqi, R.1    De La Motte, C.2    Dicorleto, P.E.3
  • 219
    • 0025817765 scopus 로고
    • Alpha-tocopherol (vitamin E) regulates vascular smooth muscle cell proliferation and protein kinase C activity
    • Boscoboinik D, Szewczyk A, Azzi A. Alpha-tocopherol (vitamin E) regulates vascular smooth muscle cell proliferation and protein kinase C activity. Arch Biochem Biophys 1991; 286:264-269.
    • (1991) Arch Biochem Biophys , vol.286 , pp. 264-269
    • Boscoboinik, D.1    Szewczyk, A.2    Azzi, A.3
  • 220
    • 0029995285 scopus 로고    scopus 로고
    • Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers
    • Weber C, Erl W, Weber K, Weber P. Increased adhesiveness of isolated monocytes to endothelium is prevented by vitamin C intake in smokers. Circulation 1996; 93:1488-1492.
    • (1996) Circulation , vol.93 , pp. 1488-1492
    • Weber, C.1    Erl, W.2    Weber, K.3    Weber, P.4
  • 221
    • 0027365599 scopus 로고
    • Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
    • Marui N, Offermann MK, Swerlick R, Kunsch C, Rosen C, Ahmad M, et al. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest 1993; 92:1866-1874.
    • (1993) J Clin Invest , vol.92 , pp. 1866-1874
    • Marui, N.1    Offermann, M.K.2    Swerlick, R.3    Kunsch, C.4    Rosen, C.5    Ahmad, M.6
  • 222
    • 0029666339 scopus 로고    scopus 로고
    • Effects of 17β-estradiol on cytokine-induced endothelial cell adhesion molecule expression
    • Caulin-Glaser T, Watson CA, Pari R, Bender JR. Effects of 17β-estradiol on cytokine-induced endothelial cell adhesion molecule expression. J Clin Invest 1996; 98:36-42.
    • (1996) J Clin Invest , vol.98 , pp. 36-42
    • Caulin-Glaser, T.1    Watson, C.A.2    Pari, R.3    Bender, J.R.4
  • 223
    • 0030950540 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-κB activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis
    • Hernández-Presa M, Bustos C, Ortego M, Tuǹon J, Renedo G, Ruiz-Ortega M, et al. Angiotensin-converting enzyme inhibition prevents arterial nuclear factor-κB activation, monocyte chemoattractant protein-1 expression, and macrophage infiltration in a rabbit model of early accelerated atherosclerosis. Circulation 1997; 95:1532-1541.
    • (1997) Circulation , vol.95 , pp. 1532-1541
    • Hernández-Presa, M.1    Bustos, C.2    Ortego, M.3    Tuǹon, J.4    Renedo, G.5    Ruiz-Ortega, M.6


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