Mangiferin inhibits endoplasmic reticulum stress-associated thioredoxin-interacting protein/NLRP3 inflammasome activation with regulation of AMPK in endothelial cells

Metabolism: Clinical and Experimental

Volumn 64, Issue 3, 2015, Pages 428-437

  Song, Junna ^a   Li, Jia ^b,c   Hou, Fangjie ^a   Wang, Xiaona ^a   Liu, Baolin ^b,c  

^a HEBEI UNIVERSITY OF CHINESE MEDICINE   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

AMPK; Endoplasmic reticulum stress; Endothelial dysfunction; Mangiferin

Indexed keywords

CASPASE 3; CRYOPYRIN; ENDOTHELIN 1; GLUCOSE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MANGIFERIN; NITRIC OXIDE; PROTEIN IRE1; PROTEIN IRE1ALPHA; REACTIVE OXYGEN METABOLITE; THIOREDOXIN INTERACTING PROTEIN; UNCLASSIFIED DRUG; ANTIDIABETIC AGENT; CARRIER PROTEIN; CYTOKINE; ERN1 PROTEIN, HUMAN; NLRP3 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE; TXNIP PROTEIN, HUMAN; XANTHONE DERIVATIVE;

ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE RELEASE; DRUG MECHANISM; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GLUCOTOXICITY; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING; DRUG EFFECTS; ENZYMOLOGY; INFLAMMATION; METABOLISM; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL;

APOPTOSIS; CARRIER PROTEINS; CYTOKINES; ENDOPLASMIC RETICULUM STRESS; ENDORIBONUCLEASES; ENDOTHELIAL CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOGLYCEMIC AGENTS; INFLAMMATION; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIAL, MITOCHONDRIAL; NITRIC OXIDE; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; XANTHONES;

EID: 84921733825     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2014.11.008     Document Type: Article

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