-
1
-
-
0348048874
-
Diabetic retinopathy
-
Frank R.N. Diabetic retinopathy. New Engl. J. Med. 350 (2004) 48-58
-
(2004)
New Engl. J. Med.
, vol.350
, pp. 48-58
-
-
Frank, R.N.1
-
2
-
-
41149099068
-
Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy
-
Kern T.S. Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. Exp. Diabetes Res. 2007 (2007) 95103
-
(2007)
Exp. Diabetes Res.
, vol.2007
, pp. 95103
-
-
Kern, T.S.1
-
3
-
-
0036095059
-
Suppression of diabetic retinopathy with angiopoietin-1
-
(comment)
-
Joussen A.M., et al. Suppression of diabetic retinopathy with angiopoietin-1. Am. J. Pathol. 160 (2002) 1683-1693 (comment)
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 1683-1693
-
-
Joussen, A.M.1
-
4
-
-
33644893607
-
Pigment epithelium-derived factor (PEDF) is an endogenous anti-inflammatory factor
-
Zhang S.X., Wang J.J., Gao G., Shao C., Mott R., and Ma J.-X. Pigment epithelium-derived factor (PEDF) is an endogenous anti-inflammatory factor. FASEB J. 20 (2006) 323-325
-
(2006)
FASEB J.
, vol.20
, pp. 323-325
-
-
Zhang, S.X.1
Wang, J.J.2
Gao, G.3
Shao, C.4
Mott, R.5
Ma, J.-X.6
-
5
-
-
0035656024
-
Monocyte chemotactic protein-1 in the vitreous of patients with proliferative diabetic retinopathy
-
Mitamura Y., Takeuchi S., Matsuda A., Tagawa Y., Mizue Y., and Nishihira J. Monocyte chemotactic protein-1 in the vitreous of patients with proliferative diabetic retinopathy. Ophthalmologica 215 (2001) 415-418
-
(2001)
Ophthalmologica
, vol.215
, pp. 415-418
-
-
Mitamura, Y.1
Takeuchi, S.2
Matsuda, A.3
Tagawa, Y.4
Mizue, Y.5
Nishihira, J.6
-
6
-
-
0036742063
-
Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy
-
Ogata N., Nishikawa M., Nishimura T., Mitsuma Y., and Matsumura M. Unbalanced vitreous levels of pigment epithelium-derived factor and vascular endothelial growth factor in diabetic retinopathy. Am. J. Ophthalmol. 134 (2002) 348-353
-
(2002)
Am. J. Ophthalmol.
, vol.134
, pp. 348-353
-
-
Ogata, N.1
Nishikawa, M.2
Nishimura, T.3
Mitsuma, Y.4
Matsumura, M.5
-
7
-
-
0036517850
-
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression
-
Joussen A.M., Poulaki V., Mitsiades N., Kirchhof B., Koizumi K., Dohmen S., and Adamis A.P. Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression. FASEB J. 16 (2002) 438-440
-
(2002)
FASEB J.
, vol.16
, pp. 438-440
-
-
Joussen, A.M.1
Poulaki, V.2
Mitsiades, N.3
Kirchhof, B.4
Koizumi, K.5
Dohmen, S.6
Adamis, A.P.7
-
8
-
-
0037407757
-
VEGF164 is proinflammatory in the diabetic retina
-
Ishida S., et al. VEGF164 is proinflammatory in the diabetic retina. Invest. Ophthalmol. Vis. Sci. 44 (2003) 2155-2162
-
(2003)
Invest. Ophthalmol. Vis. Sci.
, vol.44
, pp. 2155-2162
-
-
Ishida, S.1
-
9
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Ozcan U., et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306 (2004) 457-461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Ozcan, U.1
-
10
-
-
33748069813
-
Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
-
Ozcan U., Yilmaz E., Ozcan L., Furuhashi M., Vaillancourt E., Smith R.O., Görgün C.Z., and Hotamisligil G.S. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313 (2006) 1137-1140
-
(2006)
Science
, vol.313
, pp. 1137-1140
-
-
Ozcan, U.1
Yilmaz, E.2
Ozcan, L.3
Furuhashi, M.4
Vaillancourt, E.5
Smith, R.O.6
Görgün, C.Z.7
Hotamisligil, G.S.8
-
11
-
-
55849096988
-
Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes
-
Song B., Scheuner D., Ron D., Pennathur S., and Kaufman R.J. Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J. Clin. Invest. 118 (2008) 3378-3389
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 3378-3389
-
-
Song, B.1
Scheuner, D.2
Ron, D.3
Pennathur, S.4
Kaufman, R.J.5
-
12
-
-
33750221963
-
The unfolded protein response is an important regulator of inflammatory genes in endothelial cells
-
Gargalovic P.S., et al. The unfolded protein response is an important regulator of inflammatory genes in endothelial cells. Arterioscler. Thromb. Vasc. Biol. 26 (2006) 2490-2496
-
(2006)
Arterioscler. Thromb. Vasc. Biol.
, vol.26
, pp. 2490-2496
-
-
Gargalovic, P.S.1
-
13
-
-
33645815074
-
Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression
-
Hu P., Han Z., Couvillon A.D., Kaufman R.J., and Exton J.H. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression. Mol. Cell Biol. 26 (2006) 3071-3084
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 3071-3084
-
-
Hu, P.1
Han, Z.2
Couvillon, A.D.3
Kaufman, R.J.4
Exton, J.H.5
-
14
-
-
47949099916
-
From endoplasmic-reticulum stress to the inflammatory response
-
Zhang K., and Kaufman R.J. From endoplasmic-reticulum stress to the inflammatory response. Nature 454 (2008) 455-462
-
(2008)
Nature
, vol.454
, pp. 455-462
-
-
Zhang, K.1
Kaufman, R.J.2
-
15
-
-
33748048164
-
Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids
-
Gargalovic P.S., et al. Identification of inflammatory gene modules based on variations of human endothelial cell responses to oxidized lipids. Proc. Natl. Acad. Sci. USA 103 (2006) 12741-12746
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 12741-12746
-
-
Gargalovic, P.S.1
-
16
-
-
2442572249
-
Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4
-
Roybal C.N., Yang S., Sun C.W., Hurtado D., Vander Jagt D.L., Townes T.M., and Abcouwer S.F. Homocysteine increases the expression of vascular endothelial growth factor by a mechanism involving endoplasmic reticulum stress and transcription factor ATF4. J. Biol. Chem. 279 (2004) 14844-14852
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14844-14852
-
-
Roybal, C.N.1
Yang, S.2
Sun, C.W.3
Hurtado, D.4
Vander Jagt, D.L.5
Townes, T.M.6
Abcouwer, S.F.7
-
17
-
-
20144378800
-
The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism
-
Roybal C.N., Hunsaker L.A., Barbash O., Vander Jagt D.L., and Abcouwer S.F. The oxidative stressor arsenite activates vascular endothelial growth factor mRNA transcription by an ATF4-dependent mechanism. J. Biol. Chem. 280 (2005) 20331-20339
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20331-20339
-
-
Roybal, C.N.1
Hunsaker, L.A.2
Barbash, O.3
Vander Jagt, D.L.4
Abcouwer, S.F.5
-
18
-
-
50949121779
-
Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury
-
Malabanan K.P., Kanellakis P., Bobik A., and Khachigian L.M. Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury. Circ. Res. 103 (2008) 378-387
-
(2008)
Circ. Res.
, vol.103
, pp. 378-387
-
-
Malabanan, K.P.1
Kanellakis, P.2
Bobik, A.3
Khachigian, L.M.4
-
19
-
-
0027982899
-
Oxygen-induced retinopathy in the mouse
-
Smith L.E., Wesolowski E., McLellan A., Kostyk S.K., D'Amato R., Sullivan R., and D'Amore P.A. Oxygen-induced retinopathy in the mouse. Invest. Ophthalmol. Vis. Sci. 35 (1994) 101-111
-
(1994)
Invest. Ophthalmol. Vis. Sci.
, vol.35
, pp. 101-111
-
-
Smith, L.E.1
Wesolowski, E.2
McLellan, A.3
Kostyk, S.K.4
D'Amato, R.5
Sullivan, R.6
D'Amore, P.A.7
-
20
-
-
24944589995
-
Systemic and periocular deliveries of plasminogen kringle 5 reduce vascular leakage in rat models of oxygen-induced retinopathy and diabetes
-
Zhang S.X., Sima J., Wang J.J., Shao C., Fant J., and Ma J.X. Systemic and periocular deliveries of plasminogen kringle 5 reduce vascular leakage in rat models of oxygen-induced retinopathy and diabetes. Curr. Eye Res. 30 (2005) 681-689
-
(2005)
Curr. Eye Res.
, vol.30
, pp. 681-689
-
-
Zhang, S.X.1
Sima, J.2
Wang, J.J.3
Shao, C.4
Fant, J.5
Ma, J.X.6
-
21
-
-
0942279561
-
Plasminogen kringle 5 reduces vascular leakage in the retina of rat model of the oxygen-induced retinopathy and diabetes
-
Zhang S.X., Sima J., Shao C., Fant J., Chen Y., Rohrer B., Gao G., and Ma J.-X. Plasminogen kringle 5 reduces vascular leakage in the retina of rat model of the oxygen-induced retinopathy and diabetes. Diabetologia 47 (2004) 124-131
-
(2004)
Diabetologia
, vol.47
, pp. 124-131
-
-
Zhang, S.X.1
Sima, J.2
Shao, C.3
Fant, J.4
Chen, Y.5
Rohrer, B.6
Gao, G.7
Ma, J.-X.8
-
22
-
-
33646824929
-
Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response
-
Tirosh B., Iwakoshi N.N., Glimcher L.H., and Ploegh H.L. Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response. J. Biol. Chem. 281 (2006) 5852-5860
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 5852-5860
-
-
Tirosh, B.1
Iwakoshi, N.N.2
Glimcher, L.H.3
Ploegh, H.L.4
-
23
-
-
33747893515
-
Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy
-
Zhang S.X., Wang J.J., Gao G., Parke K., and Ma J.X. Pigment epithelium-derived factor downregulates vascular endothelial growth factor (VEGF) expression and inhibits VEGF-VEGF receptor 2 binding in diabetic retinopathy. J. Mol. Endocrinol. 37 (2006) 1-12
-
(2006)
J. Mol. Endocrinol.
, vol.37
, pp. 1-12
-
-
Zhang, S.X.1
Wang, J.J.2
Gao, G.3
Parke, K.4
Ma, J.X.5
-
24
-
-
22144457454
-
The Ins2Akita mouse as a model of early retinal complications in diabetes
-
Barber A.J., et al. The Ins2Akita mouse as a model of early retinal complications in diabetes. Invest. Ophthalmol. Vis. Sci. 46 (2005) 2210-2218
-
(2005)
Invest. Ophthalmol. Vis. Sci.
, vol.46
, pp. 2210-2218
-
-
Barber, A.J.1
-
25
-
-
34250899722
-
Signal integration in the endoplasmic reticulum unfolded protein response
-
Ron D., and Walter P. Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8 (2007) 519-529
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 519-529
-
-
Ron, D.1
Walter, P.2
-
26
-
-
33947308503
-
Retinopathy of prematurity
-
Chen J., and Smith L.E. Retinopathy of prematurity. Angiogenesis 10 (2007) 133-140
-
(2007)
Angiogenesis
, vol.10
, pp. 133-140
-
-
Chen, J.1
Smith, L.E.2
-
27
-
-
11144236527
-
Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygen-induced retinopathy
-
Zhang S.X., Ma J.-X., Sima J., Chen Y., Hu M.S., Ottlecz A., and Lambrou G.N. Genetic difference in susceptibility to the blood-retina barrier breakdown in diabetes and oxygen-induced retinopathy. Am. J. Pathol. 166 (2005) 313-321
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 313-321
-
-
Zhang, S.X.1
Ma, J.-X.2
Sima, J.3
Chen, Y.4
Hu, M.S.5
Ottlecz, A.6
Lambrou, G.N.7
-
28
-
-
34248215127
-
Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration
-
de Gooyer T.E., Stevenson K.A., Humphries P., Simpson D.A., Gardiner T.A., and Stitt A.W. Retinopathy is reduced during experimental diabetes in a mouse model of outer retinal degeneration. Invest. Ophthalmol. Vis. Sci. 47 (2006) 5561-5568
-
(2006)
Invest. Ophthalmol. Vis. Sci.
, vol.47
, pp. 5561-5568
-
-
de Gooyer, T.E.1
Stevenson, K.A.2
Humphries, P.3
Simpson, D.A.4
Gardiner, T.A.5
Stitt, A.W.6
-
29
-
-
67349242577
-
Oxidized low-density lipoprotein triggers endoplasmic reticulum stress in vascular Cells
-
Circ Res, Epub ahead of print
-
Sanson, M., et al. (2008) Oxidized low-density lipoprotein triggers endoplasmic reticulum stress in vascular Cells. Prevention by oxygen-regulated protein 150 expression. Circ Res. (Epub ahead of print).
-
(2008)
Prevention by oxygen-regulated protein 150 expression
-
-
Sanson, M.1
-
30
-
-
0031877633
-
Retinal hypoxia in long-term diabetic cats
-
Linsenmeier R.A., Braun R.D., McRipley M.A., Padnick L.B., Ahmed J., Hatchell D.L., McLeod D.S., and Lutty G.A. Retinal hypoxia in long-term diabetic cats. Invest. Ophthalmol. Vis. Sci. 39 (1998) 1647-1657
-
(1998)
Invest. Ophthalmol. Vis. Sci.
, vol.39
, pp. 1647-1657
-
-
Linsenmeier, R.A.1
Braun, R.D.2
McRipley, M.A.3
Padnick, L.B.4
Ahmed, J.5
Hatchell, D.L.6
McLeod, D.S.7
Lutty, G.A.8
-
31
-
-
0942265576
-
Supplemental oxygen improves diabetic macular edema: a pilot study
-
Nguyen Q.D., Shah S.M., Van Anden E., Sung J.U., Vitale S., and Campochiaro P.A. Supplemental oxygen improves diabetic macular edema: a pilot study. Invest. Ophthalmol. Vis. Sci. 45 (2004) 617-624
-
(2004)
Invest. Ophthalmol. Vis. Sci.
, vol.45
, pp. 617-624
-
-
Nguyen, Q.D.1
Shah, S.M.2
Van Anden, E.3
Sung, J.U.4
Vitale, S.5
Campochiaro, P.A.6
-
32
-
-
33845536782
-
Ocular neovascularization: implication of endogenous angiogenic inhibitors and potential therapy
-
Zhang S.X., and Ma J.X. Ocular neovascularization: implication of endogenous angiogenic inhibitors and potential therapy. Prog. Retin. Eye Res. 26 (2007) 1-37
-
(2007)
Prog. Retin. Eye Res.
, vol.26
, pp. 1-37
-
-
Zhang, S.X.1
Ma, J.X.2
-
33
-
-
0035850826
-
The regulation of the induction of vascular endothelial growth factor at the onset of diabetes in spontaneously diabetic rats
-
Braun L., Kardon T., Reisz-Porszasz Z.S., Banhegyi G., and Mandl J. The regulation of the induction of vascular endothelial growth factor at the onset of diabetes in spontaneously diabetic rats. Life Sci. 69 (2001) 2533-2542
-
(2001)
Life Sci.
, vol.69
, pp. 2533-2542
-
-
Braun, L.1
Kardon, T.2
Reisz-Porszasz, Z.S.3
Banhegyi, G.4
Mandl, J.5
-
34
-
-
57949110908
-
Association of vitreous inflammatory factors with diabetic macular edema
-
Funatsu H., Noma H., Mimura T., Eguchi S., and Hori S. Association of vitreous inflammatory factors with diabetic macular edema. Ophthalmology 116 (2009) 73-79
-
(2009)
Ophthalmology
, vol.116
, pp. 73-79
-
-
Funatsu, H.1
Noma, H.2
Mimura, T.3
Eguchi, S.4
Hori, S.5
-
35
-
-
34247394257
-
Oxidative stress and diabetic retinopathy
-
Kowluru R.A., and Chan P.S. Oxidative stress and diabetic retinopathy. Exp. Diabetes Res. (2007) 43603
-
(2007)
Exp. Diabetes Res.
, pp. 43603
-
-
Kowluru, R.A.1
Chan, P.S.2
-
36
-
-
33644790277
-
Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis
-
Dickhout J.G., Hossain G.S., Pozza L.M., Zhou J., Lhoták S., and Austin R.C. Peroxynitrite causes endoplasmic reticulum stress and apoptosis in human vascular endothelium: implications in atherogenesis. Arterioscler. Thromb. Vasc. Biol. 25 (2005) 2623-2629
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 2623-2629
-
-
Dickhout, J.G.1
Hossain, G.S.2
Pozza, L.M.3
Zhou, J.4
Lhoták, S.5
Austin, R.C.6
-
37
-
-
43549125786
-
ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo
-
Lange P.S., Chavez J.C., Pinto J.T., Coppola G., Sun C.W., Townes T.M., Geschwind D.H., and Ratan R.R. ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo. J. Exp. Med. 205 (2008) 1227-1242
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1227-1242
-
-
Lange, P.S.1
Chavez, J.C.2
Pinto, J.T.3
Coppola, G.4
Sun, C.W.5
Townes, T.M.6
Geschwind, D.H.7
Ratan, R.R.8
-
38
-
-
57449092891
-
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion
-
Malhotra J.D., Miao H., Zhang K., Wolfson A., Pennathur S., Pipe S.W., and Kaufman R.J. Antioxidants reduce endoplasmic reticulum stress and improve protein secretion. Proc. Natl. Acad. Sci. USA 105 (2008) 18525-18530
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18525-18530
-
-
Malhotra, J.D.1
Miao, H.2
Zhang, K.3
Wolfson, A.4
Pennathur, S.5
Pipe, S.W.6
Kaufman, R.J.7
-
39
-
-
34250660448
-
Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity
-
Saito Y., Geisen P., Uppal A., and Hartnett M.E. Inhibition of NAD(P)H oxidase reduces apoptosis and avascular retina in an animal model of retinopathy of prematurity. Mol. Vis. 13 (2007) 840-853
-
(2007)
Mol. Vis.
, vol.13
, pp. 840-853
-
-
Saito, Y.1
Geisen, P.2
Uppal, A.3
Hartnett, M.E.4
-
40
-
-
45549090431
-
Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model
-
Saito Y., Uppal A., Byfield G., Budd S., Geisen P., and Hartnett M.E. Activated NAD(P)H oxidase from supplemental oxygen induces neovascularization independent of VEGF in retinopathy of prematurity model. Invest. Ophthalmol. Vis. Sci. 49 (2008) 1591-1598
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 1591-1598
-
-
Saito, Y.1
Uppal, A.2
Byfield, G.3
Budd, S.4
Geisen, P.5
Hartnett, M.E.6
|