A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 29, 2011, Pages 11756-11765

  Reiling, Jan H ^a   Clish, Clary B ^b   Carette, Jan E ^a,c   Varadarajan, Malini ^a   Brummelkamp, Thijn R ^a,d   Sabatini, David M ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

Cancer; Dolichyl phosphate (UDP N acetylglucosamine) acetylglucosaminephosphotransferase 1 (DPAGT1); Gene trap; KBM7; Melibiose permease

Indexed keywords

MAJOR FACILITATOR DOMAIN CONTAINING 2A PROTEIN; MEMBRANE PROTEIN; TUNICAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRESS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG UPTAKE; ENDOPLASMIC RETICULUM; GENE MUTATION; GENETIC SCREENING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY;

BLOTTING, WESTERN; CELL LINE; CELL SURVIVAL; ENDOPLASMIC RETICULUM; GLYCOSYLATION; HUMANS; IMMUNOPRECIPITATION; MEMBRANE TRANSPORT PROTEINS; MICROSCOPY, CONFOCAL; PROTEIN FOLDING; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; TUNICAMYCIN;

EUKARYOTA;

EID: 79961054838     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018098108     Document Type: Article

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